Year |
Citation |
Score |
2014 |
Lathuilière A, Cosson S, Lutolf MP, Schneider BL, Aebischer P. A high-capacity cell macroencapsulation system supporting the long-term survival of genetically engineered allogeneic cells. Biomaterials. 35: 779-91. PMID 24103654 DOI: 10.1016/j.biomaterials.2013.09.071 |
0.318 |
|
2013 |
Kunze A, Lengacher S, Dirren E, Aebischer P, Magistretti PJ, Renaud P. Astrocyte-neuron co-culture on microchips based on the model of SOD mutation to mimic ALS. Integrative Biology : Quantitative Biosciences From Nano to Macro. 5: 964-75. PMID 23695230 DOI: 10.1039/C3Ib40022K |
0.672 |
|
2007 |
Consiglio A, Martino S, Dolcetta D, Cusella G, Conese M, Marchesini S, Benaglia G, Wrabetz L, Orlacchio A, Déglon N, Aebischer P, Severini GM, Bordignon C. Metabolic correction in oligodendrocytes derived from metachromatic leukodystrophy mouse model by using encapsulated recombinant myoblasts. Journal of the Neurological Sciences. 255: 7-16. PMID 17341424 DOI: 10.1016/J.Jns.2007.01.010 |
0.388 |
|
2006 |
Behrstock S, Ebert A, McHugh J, Vosberg S, Moore J, Schneider B, Capowski E, Hei D, Kordower J, Aebischer P, Svendsen CN. Human neural progenitors deliver glial cell line-derived neurotrophic factor to parkinsonian rodents and aged primates. Gene Therapy. 13: 379-88. PMID 16355116 DOI: 10.1038/Sj.Gt.3302679 |
0.393 |
|
2006 |
Aebischer P, Wahlberg L, Tresco PA, Winn SR. Macroencapsulation of dopamine-secreting cells by coextrusion with an organic polymer solution1 The Biomaterials: Silver Jubilee Compendium. 61-67. DOI: 10.1016/B978-008045154-1.50009-5 |
0.639 |
|
2005 |
Ahn YH, Bensadoun JC, Aebischer P, Zurn AD, Seiger A, Björklund A, Lindvall O, Wahlberg L, Brundin P, Kaminski Schierle GS. Increased fiber outgrowth from xeno-transplanted human embryonic dopaminergic neurons with co-implants of polymer-encapsulated genetically modified cells releasing glial cell line-derived neurotrophic factor. Brain Research Bulletin. 66: 135-42. PMID 15982530 DOI: 10.1016/J.Brainresbull.2005.04.009 |
0.36 |
|
2005 |
Sajadi A, Bauer M, Thöny B, Aebischer P. Long-term glial cell line-derived neurotrophic factor overexpression in the intact nigrostriatal system in rats leads to a decrease of dopamine and increase of tetrahydrobiopterin production. Journal of Neurochemistry. 93: 1482-6. PMID 15935064 DOI: 10.1111/j.1471-4159.2005.03139.x |
0.309 |
|
2004 |
Bloch J, Bachoud-Lévi AC, Déglon N, Lefaucheur JP, Winkel L, Palfi S, Nguyen JP, Bourdet C, Gaura V, Remy P, Brugières P, Boisse MF, Baudic S, Cesaro P, Hantraye P, ... Aebischer P, et al. Neuroprotective gene therapy for Huntington's disease, using polymer-encapsulated cells engineered to secrete human ciliary neurotrophic factor: results of a phase I study. Human Gene Therapy. 15: 968-75. PMID 15585112 DOI: 10.1089/Hum.2004.15.968 |
0.309 |
|
2004 |
Schwenter F, Schneider BL, Pralong WF, Déglon N, Aebischer P. Survival of encapsulated human primary fibroblasts and erythropoietin expression under xenogeneic conditions. Human Gene Therapy. 15: 669-80. PMID 15242527 DOI: 10.1089/1043034041361172 |
0.324 |
|
2003 |
Bjerkvig R, Read TA, Vajkoczy P, Aebischer P, Pralong W, Platt S, Melvik JE, Hagen A, Dornish M. Cell therapy using encapsulated cells producing endostatin. Acta Neurochirurgica. Supplement. 88: 137-41. PMID 14531571 DOI: 10.1007/978-3-7091-6090-9_19 |
0.333 |
|
2003 |
Schneider BL, Schwenter F, Pralong WF, Aebischer P. Prevention of the initial host immuno-inflammatory response determines the long-term survival of encapsulated myoblasts genetically engineered for erythropoietin delivery. Molecular Therapy : the Journal of the American Society of Gene Therapy. 7: 506-14. PMID 12727114 DOI: 10.1016/S1525-0016(03)00055-8 |
0.316 |
|
2003 |
Bensadoun JC, Pereira de Almeida L, Fine EG, Tseng JL, Déglon N, Aebischer P. Comparative study of GDNF delivery systems for the CNS: polymer rods, encapsulated cells, and lentiviral vectors. Journal of Controlled Release : Official Journal of the Controlled Release Society. 87: 107-15. PMID 12618027 DOI: 10.1016/S0168-3659(02)00353-X |
0.404 |
|
2002 |
Ostenfeld T, Tai YT, Martin P, Déglon N, Aebischer P, Svendsen CN. Neurospheres modified to produce glial cell line-derived neurotrophic factor increase the survival of transplanted dopamine neurons. Journal of Neuroscience Research. 69: 955-65. PMID 12205689 DOI: 10.1002/jnr.10396 |
0.352 |
|
2000 |
Peduto G, Rinsch C, Schneider BL, Rolland E, Aebischer P. Long-term host unresponsiveness to encapsulated xenogeneic myoblasts after transient immunosuppression. Transplantation. 70: 78-85. PMID 10919579 |
0.336 |
|
1999 |
Boison D, Scheurer L, Tseng JL, Aebischer P, Mohler H. Seizure suppression in kindled rats by intraventricular grafting of an adenosine releasing synthetic polymer Experimental Neurology. 160: 164-174. PMID 10630201 DOI: 10.1006/Exnr.1999.7209 |
0.308 |
|
1999 |
Lysaght MJ, Aebischer P. Encapsulated cells as therapy. Scientific American. 280: 76-82. PMID 10201119 DOI: 10.1038/Scientificamerican0499-76 |
0.305 |
|
1998 |
Décosterd I, Buchser E, Gilliard N, Saydoff J, Zurn AD, Aebischer P. Intrathecal implants of bovine chromaffin cells alleviate mechanical allodynia in a rat model of neuropathic pain Pain. 76: 159-166. PMID 9696469 DOI: 10.1016/S0304-3959(98)00044-X |
0.303 |
|
1998 |
Tseng JL, Bruhn SL, Zurn AD, Aebischer P. Neurturin protects dopaminergic neurons following medial forebrain bundle axotomy. Neuroreport. 9: 1817-22. PMID 9665607 |
0.385 |
|
1998 |
Sautter J, Tseng JL, Braguglia D, Aebischer P, Spenger C, Seiler RW, Widmer HR, Zurn AD. Implants of polymer-encapsulated genetically modified cells releasing glial cell line-derived neurotrophic factor improve survival, growth, and function of fetal dopaminergic grafts Experimental Neurology. 149: 230-236. PMID 9454632 DOI: 10.1006/exnr.1997.6718 |
0.395 |
|
1997 |
Tseng JL, Baetge EE, Zurn AD, Aebischer P. GDNF reduces drug-induced rotational behavior after medial forebrain bundle transection by a mechanism not involving striatal dopamine Journal of Neuroscience. 17: 325-333. PMID 8987758 |
0.354 |
|
1997 |
Déglon N, Heyd B, Tan SA, Joseph JM, Zurn AD, Aebischer P. Central nervous system delivery of recombinant ciliary neurotrophic factor by polymer encapsulated differentiated C2C12 myoblasts. Human Gene Therapy. 7: 2135-46. PMID 8934227 DOI: 10.1089/hum.1996.7.17-2135 |
0.391 |
|
1997 |
Aebischer P, Pochon NA, Heyd B, Deglon N, Joseph JM, Zurn AD, Baetge EE, Hammang JP, Goddard M, Lysaght M, Kaplan F, Kato AC, Schluep M, Hirt L, Regli F, et al. Gene therapy for amyotrophic lateral sclerosis (ALS) using a polymer encapsulated xenogenic cell line engineered to secrete hCNTF. Human Gene Therapy. 7: 851-60. PMID 8860837 DOI: 10.1089/hum.1996.7.7-851 |
0.354 |
|
1996 |
Aebischer P, Schluep M, Déglon N, Joseph JM, Hirt L, Heyd B, Goddard M, Hammang JP, Zurn AD, Kato AC, Regli F, Baetge EE. Intrathecal delivery of CNTF using encapsulated genetically modified xenogeneic cells in amyotrophic lateral sclerosis patients. Nature Medicine. 2: 696-9. PMID 8640564 DOI: 10.1038/nm0696-696 |
0.313 |
|
1996 |
Tan S, Déglon N, Zurn A, Baetge E, Bamber B, Kato A, Aebischer P. Rescue of Motoneurons from Axotomy-Induced Cell Death by Polymer Encapsulated Cells Genetically Engineered to Release CNTF Cell Transplantation. 5: 577-587. DOI: 10.1177/096368979600500507 |
0.34 |
|
1996 |
Joseph JM, Degion N, Schluep M, Hirt L, Martinet O, Baetge E, Goddard M, Zurn A, Regli F, Aebischer P. Transplantation of an encapsulated genetically engineered cell line releasing ciliary neurotrophic factor in LOU gehrig disease Cell Transplantation. 5: 80. DOI: 10.1016/0963-6897(96)82323-2 |
0.376 |
|
1995 |
Aebischer P, Kato AC. Treatment of amyotrophic lateral sclerosis using a gene therapy approach. European Neurology. 35: 65-8. PMID 7796839 DOI: 10.1159/000117095 |
0.337 |
|
1995 |
Zurn AD, Baetge EE, Hammang JP, Tan SA, Aebischer P. Glial cell line-derived neurotrophic factor (GDNF), a new neurotrophic factor for motoneurones. Neuroreport. 6: 113-8. PMID 7703397 DOI: 10.1097/00001756-199412300-00030 |
0.353 |
|
1995 |
Vargo TG, Bekos EJ, Kim YS, Ranieri JP, Bellamkonda R, Aebischer P, Margevich DE, Thompson PM, Bright FV, Gardella JA. Synthesis and characterization of fluoropolymeric substrata with immobilized minimal peptide sequences for cell adhesion studies. I. Journal of Biomedical Materials Research. 29: 767-78. PMID 7593014 DOI: 10.1002/Jbm.820290613 |
0.556 |
|
1995 |
Sagot Y, Tan SA, Baetge E, Schmalbruch H, Kato AC, Aebischer P. Polymer encapsulated cell lines genetically engineered to release ciliary neurotrophic factor can slow down progressive motor neuronopathy in the mouse. The European Journal of Neuroscience. 7: 1313-22. PMID 7582105 DOI: 10.1111/j.1460-9568.1995.tb01122.x |
0.395 |
|
1994 |
Guénard V, Aebischer P, Bunge RP. The astrocyte inhibition of peripheral nerve regeneration is reversed by Schwann cells. Experimental Neurology. 126: 44-60. PMID 8157126 DOI: 10.1006/exnr.1994.1041 |
0.323 |
|
1994 |
Aebischer P, Goddard M, Signore AP, Timpson RL. Functional Recovery in Hemiparkinsonian Primates Transplanted with Polymer-Encapsulated PC12 Cells Experimental Neurology. 126: 151-158. PMID 7925816 DOI: 10.1006/Exnr.1994.1053 |
0.543 |
|
1994 |
Zielinski BA, Aebischer P. Chitosan as a matrix for mammalian cell encapsulation. Biomaterials. 15: 1049-56. PMID 7888575 DOI: 10.1016/0142-9612(94)90090-6 |
0.499 |
|
1993 |
Hoffman D, Breakefield XO, Short MP, Aebischer P. Transplantation of a polymer-encapsulated cell line genetically engineered to release NGF. Experimental Neurology. 122: 100-6. PMID 8339781 DOI: 10.1006/exnr.1993.1111 |
0.427 |
|
1993 |
Sagen J, Wang H, Tresco PA, Aebischer P. Transplants of immunologically isolated xenogeneic chromaffin cells provide a long-term source of pain-reducing neuroactive substances. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 2415-23. PMID 7684773 DOI: 10.1523/Jneurosci.13-06-02415.1993 |
0.651 |
|
1993 |
Sanberg PR, Emerich DF, Aebischer P, Amisetti SM, Ouellette W, Koutouzis TK, Cahill DW, Norman AB. Substance P containing polymer implants protect against striatal excitotoxicity. Brain Research. 628: 327-9. PMID 7508810 DOI: 10.1016/0006-8993(93)90974-R |
0.374 |
|
1992 |
Tresco PA, Winn SR, Tan S, Jaeger CB, Greene LA, Aebischer P. POLYMER-ENCAPSULATED PC12 CELLS: LONG-TERM SURVIVAL AND ASSOCIATED REDUCTION IN LESION-INDUCED ROTATIONAL BEHAVIOR. Cell Transplantation. 1: 255-264. PMID 28153072 |
0.701 |
|
1992 |
Valentini RF, Vargo TG, Gardella JA, Aebischer P. Electrically charged polymeric substrates enhance nerve fibre outgrowth In vitro Biomaterials. 13: 183-190. PMID 1567943 DOI: 10.1016/0142-9612(92)90069-Z |
0.362 |
|
1992 |
Winn SR, Tresco PA, Zielinski B, Sagen J, Aebischer P. Microencapsulated bovine chromaffin cells in vitro: effect of density and coseeding with a NGF-releasing cell line. Journal of Neural Transplantation & Plasticity. 3: 115-24. PMID 1515479 DOI: 10.1155/Np.1992.115 |
0.712 |
|
1992 |
Jaeger CB, Aebischer P, Tresco PA, Winn SR, Greene LA. Growth of tumour cell lines in polymer capsules: ultrastructure of encapsulated PC12 cells. Journal of Neurocytology. 21: 469-80. PMID 1500946 DOI: 10.1007/Bf01186951 |
0.73 |
|
1992 |
Tresco PA, Winn SR, Aebischer P. Polymer encapsulated neurotransmitter secreting cells. Potential treatment for Parkinson's disease. Asaio Journal (American Society For Artificial Internal Organs : 1992). 38: 17-23. PMID 1348191 DOI: 10.1097/00002480-199201000-00006 |
0.716 |
|
1992 |
Tresco PA, Winn SR, Tan S, Jaeger CB, Greene LA, Aebischer P. Polymer-encapsulated PC12 cells: long-term survival and associated reduction in lesion-induced rotational behavior. Cell Transplantation. 1: 255-64. PMID 1344297 DOI: 10.1177/0963689792001002-307 |
0.723 |
|
1992 |
Guenard V, Kleitman N, Morrissey T, Bunge R, Aebischer P. Syngeneic Schwann cells derived from adult nerves seeded in semipermeable guidance channels enhance peripheral nerve regeneration The Journal of Neuroscience. 12: 3310-3320. DOI: 10.1523/Jneurosci.12-09-03310.1992 |
0.356 |
|
1991 |
Aebischer P, Lacy PE, Gerasimidi-Vazeou A, Hauptfeld V. Production of Marked Prolongation of Islet Xenograft Survival (Rat to Mouse) by Local Release of Mouse and Rat Antilymphocyte Sera at Transplant Site Diabetes. 40: 482-485. PMID 2010049 DOI: 10.2337/Diab.40.4.482 |
0.367 |
|
1991 |
Aebischer P, Wahlberg L, Tresco PA, Winn SR. Macroencapsulation of dopamine-secreting cells by coextrusion with an organic polymer solution. Biomaterials. 12: 50-6. PMID 2009346 DOI: 10.1016/0142-9612(91)90132-T |
0.7 |
|
1991 |
Aebischer P, Tresco PA, Winn SR, Greene LA, Jaeger CB. Long-term cross-species brain transplantation of a polymer-encapsulated dopamine-secreting cell line. Experimental Neurology. 111: 269-75. PMID 1999230 DOI: 10.1016/0014-4886(91)90093-R |
0.73 |
|
1991 |
Winn SR, Tresco PA, Zielinski B, Greene LA, Jaeger CB, Aebischer P. Behavioral recovery following intrastriatal implantation of microencapsulated PC12 cells. Experimental Neurology. 113: 322-9. PMID 1915723 DOI: 10.1016/0014-4886(91)90022-5 |
0.727 |
|
1991 |
Jaeger CB, Winn SR, Tresco PA, Aebischer P. Repair of the blood-brain barrier following implantation of polymer capsules. Brain Research. 551: 163-70. PMID 1913150 DOI: 10.1016/0006-8993(91)90929-P |
0.634 |
|
1991 |
Guénard V, Valentini RF, Aebischer P. Influence of surface texture of polymeric sheets on peripheral nerve regeneration in a two-compartment guidance system Biomaterials. 12: 259-263. PMID 1878462 DOI: 10.1016/0142-9612(91)90210-2 |
0.345 |
|
1991 |
Aebischer P, Winn SR, Tresco PA, Jaeger CB, Greene LA. Transplantation of polymer encapsulated neurotransmitter secreting cells: effect of the encapsulation technique. Journal of Biomechanical Engineering. 113: 178-83. PMID 1875690 DOI: 10.1115/1.2891231 |
0.718 |
|
1991 |
Guénard V, Dinarello CA, Weston PJ, Aebischer P. Peripheral nerve regeneration is impeded by interleukin-1 receptor antagonist released from a polymeric guidance channel. Journal of Neuroscience Research. 29: 396-400. PMID 1833560 DOI: 10.1002/Jnr.490290315 |
0.308 |
|
1991 |
Fine EG, Valentini RF, Bellamkonda R, Aebischer P. Improved nerve regeneration through piezoelectric vinylidenefluoride-trifluoroethylene copolymer guidance channels Biomaterials. 12: 775-780. PMID 1799653 DOI: 10.1016/0142-9612(91)90029-A |
0.551 |
|
1991 |
Christenson L, Wahlberg L, Aebischer P. Mast cells and tissue reaction to intraperitoneally implanted polymer capsules Journal of Biomedical Materials Research. 25: 1119-1131. PMID 1778997 DOI: 10.1002/Jbm.820250906 |
0.424 |
|
1991 |
Aebischer P, Tresco PA, Sagen J, Winn SR. Transplantation of microencapsulated bovine chromaffin cells reduces lesion-induced rotational asymmetry in rats. Brain Research. 560: 43-9. PMID 1760745 DOI: 10.1016/0006-8993(91)91212-J |
0.735 |
|
1990 |
Ip TK, Galletti PM, Aebischer P. Effects of attachment substrates on the growth and differentiation of LLC-PK1 cells. In Vitro Cellular & Developmental Biology : Journal of the Tissue Culture Association. 26: 162-8. PMID 2312499 DOI: 10.1007/Bf02624108 |
0.35 |
|
1990 |
Jaeger CB, Greene LA, Tresco PA, Winn SR, Aebischer P. Polymer encapsulated dopaminergic cell lines as "alternative neural grafts". Progress in Brain Research. 82: 41-6. PMID 2290954 |
0.676 |
|
1990 |
Hoffman D, Wahlberg L, Aebischer P. NGF released from a polymer matrix prevents loss of ChAT expression in basal forebrain neurons following a fimbria-fornix lesion. Experimental Neurology. 110: 39-44. PMID 2209780 DOI: 10.1016/0014-4886(90)90049-X |
0.441 |
|
1990 |
Jaeger CB, Greene LA, Tresco PA, Winn SR, Aebischer P. Polymer encapsulated dopaminergic cell lines as 'alternative neural grafts' Progress in Brain Research. 82: 41-46. DOI: 10.1016/S0079-6123(08)62588-1 |
0.715 |
|
1989 |
Aebischer P, Salessiotis AN, Winn SR. Basic fibroblast growth factor released from synthetic guidance channels facilitates peripheral nerve regeneration across long nerve gaps. Journal of Neuroscience Research. 23: 282-289. PMID 2769793 DOI: 10.1002/Jnr.490230306 |
0.366 |
|
1989 |
Christenson L, Aebischer P, McMillan P, Galletti PM. Tissue reaction to intraperitoneal polymer implants: species difference and effects of corticoid and doxorubicin. Journal of Biomedical Materials Research. 23: 705-18. PMID 2661559 DOI: 10.1002/Jbm.820230704 |
0.366 |
|
1989 |
Winn SR, Wahlberg L, Tresco PA, Aebischer P. An encapsulated dopamine-releasing polymer alleviates experimental parkinsonism in rats. Experimental Neurology. 105: 244-50. PMID 2504616 DOI: 10.1016/0014-4886(89)90126-X |
0.668 |
|
1989 |
Winn SR, Aebischer P, Galletti PM. Brain tissue reaction to permselective polymer capsules. Journal of Biomedical Materials Research. 23: 31-44. PMID 2468675 DOI: 10.1002/Jbm.820230104 |
0.427 |
|
1989 |
Aebischer P, Guenard V, Brace S. Peripheral nerve regeneration through blind-ended semipermeable guidance channels: effect of the molecular weight cutoff The Journal of Neuroscience. 9: 3590-3595. DOI: 10.1523/Jneurosci.09-10-03590.1989 |
0.318 |
|
1988 |
Aebischer P, Winn SR, Galletti PM. Transplantation of neural tissue in polymer capsules. Brain Research. 448: 364-8. PMID 3378159 DOI: 10.1016/0006-8993(88)91278-4 |
0.384 |
|
1988 |
Aebischer P, Goddard MB, Sasken HF, Hunter TJ, Galletti PM. Tissue reaction to fabrics coated with turbostratic carbon: subcutaneous versus vascular implants. Biomaterials. 9: 80-85. PMID 2964876 DOI: 10.1016/0142-9612(88)90075-0 |
0.334 |
|
1988 |
Galletti PM, Aebischer P, Sasken HF, Goddard MB, Chiu T. Experience with fully bioresorbable aortic grafts in the dog. Surgery. 103: 231-241. DOI: 10.5555/Uri:Pii:0039606088902279 |
0.386 |
|
Low-probability matches (unlikely to be authored by this person) |
1998 |
Régulier E, Schneider BL, Déglon N, Beuzard Y, Aebischer P. Continuous delivery of human and mouse erythropoietin in mice by genetically engineered polymer encapsulated myoblasts Gene Therapy. 5: 1014-1022. PMID 10326023 |
0.298 |
|
1988 |
Aebischer P, Valentini RF, Winn SR, Galletti PM. The use of a semi-permeable tube as a guidance channel for a transected rabbit optic nerve Progress in Brain Research. 78: 599-603. PMID 3247455 DOI: 10.1016/S0079-6123(08)60336-2 |
0.297 |
|
1989 |
Valentini RF, Sabatini AM, Dario P, Aebischer P. Polymer electret guidance channels enhance peripheral nerve regeneration in mice. Brain Research. 480: 300-4. PMID 2713656 DOI: 10.1016/0006-8993(89)90196-0 |
0.296 |
|
2006 |
Sajadi A, Bensadoun JC, Schneider BL, Lo Bianco C, Aebischer P. Transient striatal delivery of GDNF via encapsulated cells leads to sustained behavioral improvement in a bilateral model of Parkinson disease. Neurobiology of Disease. 22: 119-29. PMID 16300956 DOI: 10.1016/j.nbd.2005.10.006 |
0.295 |
|
1988 |
Aebischer P, Guénard V, Winn SR, Valentini RF, Galletti PM. Blind-ended semipermeable guidance channels support peripheral nerve regeneration in the absence of a distal nerve stump Brain Research. 454: 179-187. PMID 3409002 DOI: 10.1016/0006-8993(88)90817-7 |
0.294 |
|
1987 |
Valentini RF, Aebischer P, Winn SR, Galletti PM. Collagen- and laminin-containing gels impede peripheral nerve regeneration through semipermeable nerve guidance channels Experimental Neurology. 98: 350-356. PMID 3666083 DOI: 10.1016/0014-4886(87)90247-0 |
0.293 |
|
1996 |
Buchser E, Goddard M, Heyd B, Joseph JM, Favre J, de Tribolet N, Lysaght M, Aebischer P. Immunoisolated xenogenic chromaffin cell therapy for chronic pain. Initial clinical experience. Anesthesiology. 85: 1005-12; discussion . PMID 8916816 DOI: 10.1097/00000542-199611000-00007 |
0.291 |
|
2000 |
Zurn AD, Henry H, Schluep M, Aubert V, Winkel L, Eilers B, Bachmann C, Aebischer P. Evaluation of an intrathecal immune response in amyotrophic lateral sclerosis patients implanted with encapsulated genetically engineered xenogeneic cells Cell Transplantation. 9: 471-484. PMID 11038064 |
0.29 |
|
1999 |
Dalle B, Payen E, Regulier E, Deglon N, Rouyer-Fessard P, Beuzard Y, Aebischer P. Improvement of mouse β-thalassemia upon erythropoietin delivery by encapsulated myoblasts Gene Therapy. 6: 157-161. PMID 10435099 DOI: 10.1038/sj.gt.3300812 |
0.287 |
|
1998 |
Borkenhagen M, Stoll RC, Neuenschwander P, Suter UW, Aebischer P. In vivo performance of a new biodegradable polyester urethane system used as a nerve guidance channel. Biomaterials. 19: 2155-65. PMID 9884056 DOI: 10.1016/S0142-9612(98)00122-7 |
0.285 |
|
2000 |
Hottinger AF, Azzouz M, Deglon N, Aebischer P, Zurn AD. Complete and long-term rescue of lesioned adult motoneurons by lentiviral-mediated expression of glial cell line-derived neurotrophic factor in the facial nucleus Journal of Neuroscience. 20: 5587-5593. PMID 10908595 |
0.285 |
|
1987 |
Aebischer P, Valentini RF, Dario P, Domenici C, Galletti PM. Piezoelectric guidance channels enhance regeneration in the mouse sciatic nerve after axotomy. Brain Research. 436: 165-8. PMID 3690349 DOI: 10.1016/0006-8993(87)91570-8 |
0.284 |
|
2000 |
Bachoud-Lévi AC, Déglon N, Nguyen JP, Bloch J, Bourdet C, Winkel L, Rémy P, Goddard M, Lefaucheur JP, Brugières P, Baudic S, Cesaro P, Peschanski M, Aebischer P. Neuroprotective gene therapy for Huntington's disease using a polymer encapsulated BHK cell line engineered to secrete human CNTF. Human Gene Therapy. 11: 1723-9. PMID 10954906 DOI: 10.1089/10430340050111377 |
0.283 |
|
1993 |
Makohliso SA, Valentini RF, Aebischer P. Magnitude and polarity of a fluoroethylene propylene electret substrate charge influences neurite outgrowth in vitro Journal of Biomedical Materials Research. 27: 1075-1085. PMID 8408120 DOI: 10.1002/Jbm.820270813 |
0.282 |
|
1998 |
Vejsada R, Tseng JL, Lindsay RM, Acheson A, Aebischer P, Kato AC. Synergistic but transient rescue effects of BDNF and GDNF on axotomized neonatal motoneurons. Neuroscience. 84: 129-39. PMID 9522368 DOI: 10.1016/S0306-4522(97)00497-1 |
0.278 |
|
2005 |
Klein SM, Behrstock S, McHugh J, Hoffmann K, Wallace K, Suzuki M, Aebischer P, Svendsen CN. GDNF delivery using human neural progenitor cells in a rat model of ALS. Human Gene Therapy. 16: 509-21. PMID 15871682 DOI: 10.1089/Hum.2005.16.509 |
0.276 |
|
2001 |
Zurn AD, Widmer HR, Aebischer P. Sustained delivery of GDNF: Towards a treatment for Parkinson's disease Brain Research Reviews. 36: 222-229. PMID 11690619 DOI: 10.1016/S0165-0173(01)00098-4 |
0.275 |
|
2002 |
Palfi S, Leventhal L, Chu Y, Ma SY, Emborg M, Bakay R, Déglon N, Hantraye P, Aebischer P, Kordower JH. Lentivirally delivered glial cell line-derived neurotrophic factor increases the number of striatal dopaminergic neurons in primate models of nigrostriatal degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 4942-54. PMID 12077191 DOI: 10.1523/Jneurosci.22-12-04942.2002 |
0.275 |
|
1989 |
Ip TK, Aebischer P. Renal epithelial-cell-controlled solute transport across permeable membranes as the foundation for a bioartificial kidney. Artificial Organs. 13: 58-65. PMID 2653286 DOI: 10.1111/J.1525-1594.1989.Tb02833.X |
0.273 |
|
1996 |
Zum AD, Tseng J, Aebischer P. Symptomatic cell therapies cells as biological minipumps European Neurology. 36: 405-408. |
0.272 |
|
1994 |
Kokaia M, Aebischer P, Elmér E, Bengzon J, Kalén P, Kokaia Z, Lindvall O. Seizure suppression in kindling epilepsy by intracerebral implants of GABA- but not by noradrenaline-releasing polymer matrices. Experimental Brain Research. 100: 385-94. PMID 7813677 DOI: 10.1007/Bf02738399 |
0.266 |
|
2001 |
Schneider BL, Peduto G, Aebischer P. A self-immunomodulating myoblast cell line for erythropoietin delivery. Gene Therapy. 8: 58-66. PMID 11402302 DOI: 10.1038/sj.gt.3301356 |
0.264 |
|
1990 |
Aebischer P, Guénard V, Valentini RF. The morphology of regenerating peripheral nerves is modulated by the surface microgeometry of polymeric guidance channels Brain Research. 531: 211-218. PMID 2289122 DOI: 10.1016/0006-8993(90)90776-8 |
0.264 |
|
2012 |
Aebischer P, Tan SA, Déglon N, Heyd B, Zurn A, Baetge E, Sagot Y, Kato A. Encapsulation of neurotrophic factor-releasing cells for the treatment of neurodegenerative diseases. Restorative Neurology and Neuroscience. 8: 65-6. PMID 21551809 DOI: 10.3233/RNN-1995-81215 |
0.264 |
|
2009 |
Redmond DE, Elsworth JD, Roth RH, Leranth C, Collier TJ, Blanchard B, Bjugstad KB, Samulski RJ, Aebischer P, Sladek JR. Embryonic substantia nigra grafts in the mesencephalon send neurites to the host striatum in non-human primate after overexpression of GDNF. The Journal of Comparative Neurology. 515: 31-40. PMID 19399891 DOI: 10.1002/Cne.22028 |
0.263 |
|
1987 |
VALENTINI RF, AEBISCHER P, WINN SR, PANOL G, GALLETTI PM. Bridging a Transected Rat Optic Nerve with a Semipermeable Guidance Channel Annals of the New York Academy of Sciences. 495: 800-803. DOI: 10.1111/J.1749-6632.1987.Tb23743.X |
0.26 |
|
2008 |
Emborg ME, Ebert AD, Moirano J, Peng S, Suzuki M, Capowski E, Joers V, Roitberg BZ, Aebischer P, Svendsen CN. GDNF-secreting human neural progenitor cells increase tyrosine hydroxylase and VMAT2 expression in MPTP-treated cynomolgus monkeys. Cell Transplantation. 17: 383-95. PMID 18522241 DOI: 10.3727/096368908784423300 |
0.26 |
|
2004 |
Kishima H, Poyot T, Bloch J, Dauguet J, Condé F, Dollé F, Hinnen F, Pralong W, Palfi S, Déglon N, Aebischer P, Hantraye P. Encapsulated GDNF-producing C2C12 cells for Parkinson's disease: a pre-clinical study in chronic MPTP-treated baboons. Neurobiology of Disease. 16: 428-39. PMID 15193299 DOI: 10.1016/J.Nbd.2004.03.012 |
0.259 |
|
2000 |
Ridet JL, Déglon N, Aebischer P. Gene transfer techniques for the delivery of GDNF in Parkinson's disease Novartis Foundation Symposium. 231: 202-215. PMID 11131539 |
0.257 |
|
2012 |
Gaugler MN, Genc O, Bobela W, Mohanna S, Ardah MT, El-Agnaf OM, Cantoni M, Bensadoun JC, Schneggenburger R, Knott GW, Aebischer P, Schneider BL. Nigrostriatal overabundance of α-synuclein leads to decreased vesicle density and deficits in dopamine release that correlate with reduced motor activity. Acta Neuropathologica. 123: 653-69. PMID 22361813 DOI: 10.1007/s00401-012-0963-y |
0.254 |
|
1996 |
Makohliso SA, Aebischer P, Giovangrandi L, Buhlmann HJ, Dutoit M. Biomimetic materials approach towards the development of a neural cell-based biosensor Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 81-82. |
0.249 |
|
2007 |
Capowski EE, Schneider BL, Ebert AD, Seehus CR, Szulc J, Zufferey R, Aebischer P, Svendsen CN. Lentiviral vector-mediated genetic modification of human neural progenitor cells for ex vivo gene therapy. Journal of Neuroscience Methods. 163: 338-49. PMID 17397931 DOI: 10.1016/J.Jneumeth.2007.02.022 |
0.248 |
|
2001 |
Rinsch C, Peduto G, Schneider BL, Aebischer P. Inducing host acceptance to encapsulated xenogeneic myoblasts. Transplantation. 71: 345-51. PMID 11233892 |
0.248 |
|
1996 |
Zurn AD, Tseng J, Aebischer P. Treatment of Parkinson's disease. Symptomatic cell therapies: cells as biological minipumps European Neurology. 36: 405-408. PMID 8954314 |
0.246 |
|
2004 |
Schwenter F, Bouche N, Pralong WF, Aebischer P. In vivo calcium deposition on polyvinyl alcohol matrix used in hollow fiber cell macroencapsulation devices. Biomaterials. 25: 3861-8. PMID 15020162 DOI: 10.1016/j.biomaterials.2003.10.030 |
0.243 |
|
2002 |
Aszmann OC, Korak KJ, Kropf N, Fine E, Aebischer P, Frey M. Simultaneous GDNF and BDNF application leads to increased motoneuron survival and improved functional outcome in an experimental model for obstetric brachial plexus lesions. Plastic and Reconstructive Surgery. 110: 1066-72. PMID 12198419 DOI: 10.1097/01.PRS.0000020990.82332.43 |
0.24 |
|
2003 |
Déglon N, Aubert V, Spertini F, Winkel L, Aebischer P. Presence of Gal-alpha1,3Gal epitope on xenogeneic lines: implications for cellular gene therapy based on the encapsulation technology. Xenotransplantation. 10: 204-13. PMID 12694540 DOI: 10.1034/j.1399-3089.2003.00110.x |
0.24 |
|
1996 |
Tan SA, Aebischer P. The problems of delivering neuroactive molecules to the CNS Ciba Foundation Symposia. 211-239. PMID 8866136 |
0.239 |
|
2012 |
Tseng JL, Aebischer P. Encapsulated cell implants as a novel treatment for Parkinson's disease. Methods in Molecular Medicine. 62: 279-88. PMID 21318783 DOI: 10.1385/1-59259-142-6:279 |
0.236 |
|
1995 |
Rensing-Ehl A, Frei K, Flury R, Matiba B, Mariani SM, Weller M, Aebischer P, Krammer PH, Fontana A. Local Fas/APO-1 (CD95) ligand-mediated tumor cell killing in vivo. European Journal of Immunology. 25: 2253-8. PMID 7545115 DOI: 10.1002/eji.1830250821 |
0.233 |
|
2002 |
Sommer B, Rinsch C, Payen E, Dalle B, Schneider B, Déglon N, Henri A, Beuzard Y, Aebischer P. Long-term doxycycline-regulated secretion of erythropoietin by encapsulated myoblasts Molecular Therapy. 6: 155-161. PMID 12161181 DOI: 10.1006/mthe.2002.0646 |
0.231 |
|
1999 |
Rinsch C, Schneider BL, Aebischer P. Highlights of the cell transplantation meeting at Montreux, March 1999. Cell Transplantation. 8: 571-6. PMID 10701484 DOI: 10.1177/096368979900800601 |
0.23 |
|
1984 |
Aebischer P, Schultz W. The activity of pars compacta neurons of the monkey substantia nigra is depressed by apomorphine. Neuroscience Letters. 50: 25-9. PMID 6493628 DOI: 10.1016/0304-3940(84)90456-7 |
0.229 |
|
2014 |
Lathuilière A, Bohrmann B, Kopetzki E, Schweitzer C, Jacobsen H, Moniatte M, Aebischer P, Schneider BL. Genetic engineering of cell lines using lentiviral vectors to achieve antibody secretion following encapsulated implantation. Biomaterials. 35: 792-802. PMID 24344356 DOI: 10.1016/j.biomaterials.2013.10.026 |
0.229 |
|
2011 |
Marroquin Belaunzaran O, Cordero MI, Setola V, Bianchi S, Galli C, Bouche N, Mlynarik V, Gruetter R, Sandi C, Bensadoun JC, Molinari M, Aebischer P. Chronic delivery of antibody fragments using immunoisolated cell implants as a passive vaccination tool. Plos One. 6: e18268. PMID 21533130 DOI: 10.1371/Journal.Pone.0018268 |
0.228 |
|
2015 |
Sotelo-Hitschfeld T, Niemeyer MI, Mächler P, Ruminot I, Lerchundi R, Wyss MT, Stobart J, Fernández-Moncada I, Valdebenito R, Garrido-Gerter P, Contreras-Baeza Y, Schneider BL, Aebischer P, Lengacher S, San Martín A, et al. Channel-mediated lactate release by K⁺-stimulated astrocytes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 4168-78. PMID 25762664 DOI: 10.1523/Jneurosci.5036-14.2015 |
0.228 |
|
1999 |
Hottinger AF, Aebischer P. Treatment of diseases of the central nervous system using encapsulated cells Advances and Technical Standards in Neurosurgery. 25: 3-20. PMID 10370715 |
0.226 |
|
2007 |
Suzuki M, McHugh J, Tork C, Shelley B, Klein SM, Aebischer P, Svendsen CN. GDNF secreting human neural progenitor cells protect dying motor neurons, but not their projection to muscle, in a rat model of familial ALS. Plos One. 2: e689. PMID 17668067 DOI: 10.1371/Journal.Pone.0000689 |
0.225 |
|
2000 |
Bensadoun JC, Déglon N, Tseng JL, Ridet JL, Zurn AD, Aebischer P. Lentiviral vectors as a gene delivery system in the mouse midbrain: Cellular and behavioral improvements in a 6-OHDA model of Parkinson's disease using GDNF Experimental Neurology. 164: 15-24. PMID 10877911 DOI: 10.1006/exnr.2000.7409 |
0.223 |
|
1997 |
Rinsch C, Régulier E, Déglon N, Dalle B, Beuzard Y, Aebischer P. A gene therapy approach to regulated delivery of erythropoietin as a function of oxygen tension Human Gene Therapy. 8: 1881-1889. PMID 9382954 |
0.222 |
|
2004 |
Sajadi A, Schneider BL, Aebischer P. Wlds-mediated protection of dopaminergic fibers in an animal model of Parkinson disease. Current Biology : Cb. 14: 326-30. PMID 14972684 DOI: 10.1016/j.cub.2004.01.053 |
0.221 |
|
1998 |
Borkenhagen M, Clémence JF, Sigrist H, Aebischer P. Three-dimensional extracellular matrix engineering in the nervous system Journal of Biomedical Materials Research. 40: 392-400. PMID 9570070 DOI: 10.1002/(SICI)1097-4636(19980603)40:3<392::AID-JBM8>3.0.CO;2-C |
0.221 |
|
2001 |
Huber A, Padrun V, Déglon N, Aebischer P, Möhler H, Boison D. Grafts of adenosine-releasing cells suppress seizures in kindling epilepsy Proceedings of the National Academy of Sciences of the United States of America. 98: 7611-7616. PMID 11404469 DOI: 10.1073/Pnas.131102898 |
0.22 |
|
2002 |
Pericin M, Althage A, Freigang S, Hengartner H, Rolland E, Dupraz P, Thorens B, Aebischer P, Zinkernagel RM. Allogeneic beta-islet cells correct diabetes and resist immune rejection. Proceedings of the National Academy of Sciences of the United States of America. 99: 8203-6. PMID 12060765 DOI: 10.1073/pnas.122241299 |
0.219 |
|
2006 |
Ridet JL, Bensadoun JC, Déglon N, Aebischer P, Zurn AD. Lentivirus-mediated expression of glutathione peroxidase: neuroprotection in murine models of Parkinson's disease. Neurobiology of Disease. 21: 29-34. PMID 16023352 DOI: 10.1016/j.nbd.2005.06.003 |
0.214 |
|
1994 |
Aebischer P, Buchser E, Joseph JM, Favre J, de Tribolet N, Lysaght M, Rudnick S, Goddard M. TRANSPLANTATION IN HUMANS OF ENCAPSULATED XENOGENEIC CELLS WITHOUT IMMUNOSUPPRESSION Transplantation. 58: 1275-1277. DOI: 10.1097/00007890-199412150-00025 |
0.213 |
|
1994 |
Levi A, Guenard V, Aebischer P, Bunge R. The functional characteristics of Schwann cells cultured from human peripheral nerve after transplantation into a gap within the rat sciatic nerve The Journal of Neuroscience. 14: 1309-1319. DOI: 10.1523/JNEUROSCI.14-03-01309.1994 |
0.213 |
|
1999 |
Aebischer P, Kato A. The Cell Transplant Society Fourth International Congress: Welcome Address Cell Transplantation. 8: 1-1. DOI: 10.1177/096368979900800201 |
0.213 |
|
2000 |
Aebischer P. The contribution of encapsulation to cell therapy European Cytokine Network. 11: 327-328. |
0.212 |
|
2002 |
Barras FM, Pasche P, Bouche N, Aebischer P, Zurn AD. Glial cell line-derived neurotrophic factor released by synthetic guidance channels promotes facial nerve regeneration in the rat. Journal of Neuroscience Research. 70: 746-55. PMID 12444596 DOI: 10.1002/jnr.10434 |
0.21 |
|
2008 |
Suzuki M, McHugh J, Tork C, Shelley B, Hayes A, Bellantuono I, Aebischer P, Svendsen CN. Direct muscle delivery of GDNF with human mesenchymal stem cells improves motor neuron survival and function in a rat model of familial ALS. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 2002-10. PMID 18797452 DOI: 10.1038/Mt.2008.197 |
0.208 |
|
2002 |
de Almeida LP, Ross CA, Zala D, Aebischer P, Déglon N. Lentiviral-mediated delivery of mutant huntingtin in the striatum of rats induces a selective neuropathology modulated by polyglutamine repeat size, huntingtin expression levels, and protein length. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 3473-83. PMID 11978824 DOI: 10.1523/Jneurosci.22-09-03473.2002 |
0.205 |
|
2006 |
Emborg ME, Roitberg BZ, Moirano J, Zufferey R, Ebert AD, Joers V, Holden J, Converse AK, Koprich JB, Kordower JH, Aebischer P. Lentiviral Delivery of Glial Cell Line-derived Neurotrophic Factor in Aged 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated Rhesus Monkeys 883. Neurosurgery. 59: 481-482. PMID 28180727 DOI: 10.1227/00006123-200608000-00121 |
0.204 |
|
2006 |
Aebischer P, Goddard M, Galletti PM, Lysaght M. Biomaterials and Artificial Organs Materials Science and Technology. DOI: 10.1002/9783527603978.Mst0163 |
0.201 |
|
1997 |
Pochon NAM, Menoud A, Tseng JL, Zurn AD, Aebischer P. Neuronal GDNF expression in the adult rat nervous system identified by in situ hybridization European Journal of Neuroscience. 9: 463-471. PMID 9104588 DOI: 10.1111/j.1460-9568.1997.tb01623.x |
0.198 |
|
2000 |
Kordower JH, Emborg ME, Bloch J, Ma SY, Chu Y, Leventhal L, McBride J, Chen EY, Palfi S, Roitberg BZ, Brown WD, Holden JE, Pyzalski R, Taylor MD, Carvey P, ... ... Aebischer P, et al. Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease. Science (New York, N.Y.). 290: 767-73. PMID 11052933 DOI: 10.1126/Science.290.5492.767 |
0.197 |
|
2002 |
Fine EG, Decosterd I, Papaloïzos M, Zurn AD, Aebischer P. GDNF and NGF released by synthetic guidance channels support sciatic nerve regeneration across a long gap. The European Journal of Neuroscience. 15: 589-601. PMID 11886440 DOI: 10.1046/j.1460-9568.2002.01892.x |
0.197 |
|
2005 |
Zala D, Benchoua A, Brouillet E, Perrin V, Gaillard MC, Zurn AD, Aebischer P, Déglon N. Progressive and selective striatal degeneration in primary neuronal cultures using lentiviral vector coding for a mutant huntingtin fragment. Neurobiology of Disease. 20: 785-98. PMID 16006135 DOI: 10.1016/J.Nbd.2005.05.017 |
0.195 |
|
2001 |
De Almeida LP, Zala D, Aebischer P, Déglon N. Neuroprotective effect of a CNTF-expressing lentiviral vector in the quinolinic acid rat model of Huntington's disease Neurobiology of Disease. 8: 433-446. PMID 11442352 DOI: 10.1006/nbdi.2001.0388 |
0.194 |
|
1994 |
Kokaia M, Aebischer P, Elm�r E, Bengzon J, Kal�n P, Kokaia Z, Lindvall O. Seizure suppression in kindling epilepsy by intracerebral implants of GABA- but not by noradrenaline-releasing polymer matrices Experimental Brain Research. 79. DOI: 10.1007/BF00229179 |
0.191 |
|
2009 |
Ulusoy A, Sahin G, Björklund T, Aebischer P, Kirik D. Dose optimization for long-term rAAV-mediated RNA interference in the nigrostriatal projection neurons. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 1574-84. PMID 19584816 DOI: 10.1038/Mt.2009.142 |
0.19 |
|
1999 |
Kordower JH, Bloch J, Ma SY, Chu Y, Palfi S, Roitberg BZ, Emborg M, Hantraye P, Déglon N, Aebischer P. Lentiviral gene transfer to the nonhuman primate brain. Experimental Neurology. 160: 1-16. PMID 10630186 DOI: 10.1006/Exnr.1999.7178 |
0.189 |
|
2000 |
Déglon N, Tseng JL, Bensadoun JC, Zurn AD, Arsenijevic Y, De Almeida LP, Zufferey R, Trono D, Aebischer P. Self-inactivating lentiviral vectors with enhanced transgene expression as potential gene transfer system in Parkinson's disease Human Gene Therapy. 11: 179-190. PMID 10646649 DOI: 10.1089/10430340050016256 |
0.188 |
|
2013 |
Krakora D, Mulcrone P, Meyer M, Lewis C, Bernau K, Gowing G, Zimprich C, Aebischer P, Svendsen CN, Suzuki M. Synergistic effects of GDNF and VEGF on lifespan and disease progression in a familial ALS rat model. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 1602-10. PMID 23712039 DOI: 10.1038/Mt.2013.108 |
0.188 |
|
2003 |
Schneider BL, Aebischer P. Cellular implants: pioneers in xenotransplantation? Xenotransplantation. 10: 96-7. PMID 12588642 DOI: 10.1034/j.1399-3089.2003.02086.x |
0.187 |
|
2006 |
Blanco-Bose WE, Schneider BL, Aebischer P. Inducing tolerance to a soluble foreign antigen by encapsulated cell transplants. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 447-56. PMID 16209937 DOI: 10.1016/J.Ymthe.2005.08.010 |
0.186 |
|
1992 |
McCormack ML, Goddard M, Guénard V, Aebischer P. Comparison of dorsal and ventral spinal root regeneration through semipermeable guidance channels. The Journal of Comparative Neurology. 313: 449-56. PMID 1770168 DOI: 10.1002/cne.903130305 |
0.186 |
|
2002 |
Régulier E, Pereira de Almeida L, Sommer B, Aebischer P, Déglon N. Dose-dependent neuroprotective effect of ciliary neurotrophic factor delivered via tetracycline-regulated lentiviral vectors in the quinolinic acid rat model of Huntington's disease. Human Gene Therapy. 13: 1981-90. PMID 12427308 DOI: 10.1089/10430340260355383 |
0.185 |
|
1999 |
Bensadoun JC, Mirochnitchenko O, Inouye M, Aebischer P, Zurn AD. Attenuation of 6-OHDA-induced neurotoxicity in glutathione peroxidase transgenic mice. The European Journal of Neuroscience. 10: 3231-6. PMID 9786216 DOI: 10.1046/j.1460-9568.1998.00345.x |
0.183 |
|
1996 |
Borkenhagen M, Aebischer P. Tissue-Engineering Approaches for Central and Peripheral Nervous-System Regeneration Mrs Bulletin. 21: 59-61. DOI: 10.1557/S0883769400031869 |
0.179 |
|
2009 |
Dusonchet J, Bensadoun JC, Schneider BL, Aebischer P. Targeted overexpression of the parkin substrate Pael-R in the nigrostriatal system of adult rats to model Parkinson's disease. Neurobiology of Disease. 35: 32-41. PMID 19348945 DOI: 10.1016/j.nbd.2009.03.013 |
0.178 |
|
2000 |
Mittoux V, Joseph JM, Conde F, Palfi S, Dautry C, Poyot T, Bloch J, Deglon N, Ouary S, Nimchinsky EA, Brouillet E, Hof PR, Peschanski M, Aebischer P, Hantraye P. Restoration of cognitive and motor functions by ciliary neurotrophic factor in a primate model of Huntington's disease. Human Gene Therapy. 11: 1177-87. PMID 10834619 DOI: 10.1089/10430340050015220 |
0.178 |
|
2008 |
Bauer M, Szulc J, Meyer M, Jensen CH, Terki TA, Meixner A, Kinkl N, Gasser T, Aebischer P, Ueffing M. Delta-like 1 participates in the specification of ventral midbrain progenitor derived dopaminergic neurons. Journal of Neurochemistry. 104: 1101-15. PMID 17986227 DOI: 10.1111/j.1471-4159.2007.05037.x |
0.175 |
|
2001 |
Rinsch C, Quinodoz P, Pittet B, Alizadeh N, Baetens D, Montandon D, Aebischer P, Pepper MS. Delivery of FGF-2 but not VEGF by encapsulated genetically engineered myoblasts improves survival and vascularization in a model of acute skin flap ischemia Gene Therapy. 8: 523-533. PMID 11319619 DOI: 10.1038/sj.gt.3301436 |
0.174 |
|
1996 |
Borkenhagen M, Clemence JF, Aebischer P. Development of a bioartificial synthetic extracellular matrix-equivalent for nerve regeneration Transactions of the Annual Meeting of the Society For Biomaterials in Conjunction With the International Biomaterials Symposium. 2: 229. |
0.172 |
|
2000 |
Cisterni C, Henderson CE, Aebischer P, Pettmann B, Déglon N. Efficient gene transfer and expression of biologically active glial cell line-derived neurotrophic factor in rat motoneurons transduced wit lentiviral vectors. Journal of Neurochemistry. 74: 1820-8. PMID 10800924 DOI: 10.1046/j.1471-4159.2000.0741820.x |
0.171 |
|
1996 |
Zurn AD, Winkel L, Menoud A, Djabali K, Aebischer P. Combined effects of GDNF, BDNF, and CNTF on motoneuron differentiation in vitro. Journal of Neuroscience Research. 44: 133-41. PMID 8723221 DOI: 10.1002/(SICI)1097-4547(19960415)44:2<133::AID-JNR5>3.0.CO;2-E |
0.171 |
|
2004 |
Zala D, Bensadoun JC, Pereira de Almeida L, Leavitt BR, Gutekunst CA, Aebischer P, Hayden MR, Déglon N. Long-term lentiviral-mediated expression of ciliary neurotrophic factor in the striatum of Huntington's disease transgenic mice. Experimental Neurology. 185: 26-35. PMID 14697316 DOI: 10.1016/J.Expneurol.2003.09.002 |
0.171 |
|
2007 |
Schneider BL, Seehus CR, Capowski EE, Aebischer P, Zhang SC, Svendsen CN. Over-expression of alpha-synuclein in human neural progenitors leads to specific changes in fate and differentiation. Human Molecular Genetics. 16: 651-66. PMID 17309880 DOI: 10.1093/Hmg/Ddm008 |
0.17 |
|
2004 |
Lo Bianco C, Schneider BL, Bauer M, Sajadi A, Brice A, Iwatsubo T, Aebischer P. Lentiviral vector delivery of parkin prevents dopaminergic degeneration in an alpha-synuclein rat model of Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 101: 17510-5. PMID 15576511 DOI: 10.1073/pnas.0405313101 |
0.17 |
|
2003 |
Schwenter F, Déglon N, Aebischer P. Optimization of human erythropoietin secretion from MLV-infected human primary fibroblasts used for encapsulated cell therapy. The Journal of Gene Medicine. 5: 246-57. PMID 12666190 DOI: 10.1002/jgm.338 |
0.17 |
|
1995 |
Xu XM, Guénard V, Kleitman N, Aebischer P, Bunge MB. A combination of BDNF and NT-3 promotes supraspinal axonal regeneration into Schwann cell grafts in adult rat thoracic spinal cord. Experimental Neurology. 134: 261-72. PMID 7556546 DOI: 10.1006/Exnr.1995.1056 |
0.17 |
|
1999 |
Bamber NI, Li H, Aebischer P, Xu XM. Fetal spinal cord tissue in mini-guidance channels promotes longitudinal axonal growth after grafting into hemisected adult rat spinal cords Neural Plasticity. 6: 103-121. DOI: 10.1155/NP.1999.103 |
0.169 |
|
2004 |
Lo Bianco C, Déglon N, Pralong W, Aebischer P. Lentiviral nigral delivery of GDNF does not prevent neurodegeneration in a genetic rat model of Parkinson's disease. Neurobiology of Disease. 17: 283-9. PMID 15474365 DOI: 10.1016/j.nbd.2004.06.008 |
0.169 |
|
2016 |
Lathuilière A, Laversenne V, Astolfo A, Kopetzki E, Jacobsen H, Stampanoni M, Bohrmann B, Schneider BL, Aebischer P. A subcutaneous cellular implant for passive immunization against amyloid-β reduces brain amyloid and tau pathologies. Brain : a Journal of Neurology. PMID 26956423 DOI: 10.1093/brain/aww036 |
0.169 |
|
2013 |
Löw K, Aebischer P, Schneider BL. Direct and retrograde transduction of nigral neurons with AAV6, 8, and 9 and intraneuronal persistence of viral particles. Human Gene Therapy. 24: 613-29. PMID 23600720 DOI: 10.1089/hum.2012.174 |
0.168 |
|
2001 |
Arsenijevic Y, Weiss S, Schneider B, Aebischer P. Insulin-like growth factor-1 is necessary for neural stem cell proliferation and demonstrates distinct actions of epidermal growth factor and fibroblast growth factor-2 Journal of Neuroscience. 21: 7194-7202. PMID 11549730 |
0.167 |
|
2009 |
Emborg ME, Moirano J, Raschke J, Bondarenko V, Zufferey R, Peng S, Ebert AD, Joers V, Roitberg B, Holden JE, Koprich J, Lipton J, Kordower JH, Aebischer P. Response of aged parkinsonian monkeys to in vivo gene transfer of GDNF. Neurobiology of Disease. 36: 303-11. PMID 19660547 DOI: 10.1016/J.Nbd.2009.07.022 |
0.165 |
|
2003 |
Régulier E, Trottier Y, Perrin V, Aebischer P, Déglon N. Early and reversible neuropathology induced by tetracycline-regulated lentiviral overexpression of mutant huntingtin in rat striatum. Human Molecular Genetics. 12: 2827-36. PMID 12952868 DOI: 10.1093/hmg/ddg305 |
0.164 |
|
2006 |
Pardo R, Colin E, Régulier E, Aebischer P, Déglon N, Humbert S, Saudou F. Inhibition of calcineurin by FK506 protects against polyglutamine-huntingtin toxicity through an increase of huntingtin phosphorylation at S421. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1635-45. PMID 16452687 DOI: 10.1523/Jneurosci.3706-05.2006 |
0.163 |
|
1997 |
Pizzorusso T, Porciatti V, Tseng JL, Aebischer P, Maffei L. Transplant of polymer-encapsulated cells genetically engineered to release nerve growth factor allows a normal functional development of the visual cortex in dark-reared rats. Neuroscience. 80: 307-11. PMID 9284336 DOI: 10.1016/S0306-4522(97)00182-6 |
0.161 |
|
2006 |
Szulc J, Wiznerowicz M, Sauvain MO, Trono D, Aebischer P. A versatile tool for conditional gene expression and knockdown. Nature Methods. 3: 109-16. PMID 16432520 DOI: 10.1016/J.Ymthe.2006.08.383 |
0.16 |
|
2012 |
Fauvet B, Mbefo MK, Fares MB, Desobry C, Michael S, Ardah MT, Tsika E, Coune P, Prudent M, Lion N, Eliezer D, Moore DJ, Schneider B, Aebischer P, El-Agnaf OM, et al. α-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer. The Journal of Biological Chemistry. 287: 15345-64. PMID 22315227 DOI: 10.1074/Jbc.M111.318949 |
0.157 |
|
2001 |
Bloch J, Fine EG, Bouche N, Zurn AD, Aebischer P. Nerve growth factor- and neurotrophin-3-releasing guidance channels promote regeneration of the transected rat dorsal root Experimental Neurology. 172: 425-432. PMID 11716566 DOI: 10.1006/exnr.2001.7778 |
0.155 |
|
2008 |
Runne H, Régulier E, Kuhn A, Zala D, Gokce O, Perrin V, Sick B, Aebischer P, Déglon N, Luthi-Carter R. Dysregulation of gene expression in primary neuron models of Huntington's disease shows that polyglutamine-related effects on the striatal transcriptome may not be dependent on brain circuitry. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 9723-31. PMID 18815258 DOI: 10.1523/Jneurosci.3044-08.2008 |
0.153 |
|
1998 |
Makohliso SA, Giovangrandi L, Léonard D, Mathieu HJ, Ilegems M, Aebischer P. Application of Teflon-AF® thin films for bio-patterning of neural cell adhesion Biosensors and Bioelectronics. 13: 1227-1235. PMID 9871978 DOI: 10.1016/S0956-5663(98)00036-0 |
0.151 |
|
2006 |
Arango M, Holbert S, Zala D, Brouillet E, Pearson J, Régulier E, Thakur AK, Aebischer P, Wetzel R, Déglon N, Néri C. CA150 expression delays striatal cell death in overexpression and knock-in conditions for mutant huntingtin neurotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 4649-59. PMID 16641246 DOI: 10.1523/Jneurosci.5409-05.2006 |
0.15 |
|
1995 |
Sagot Y, Dubois-Dauphin M, Tan S, de Bilbao F, Aebischer P, Martinou J, Kato A. Bcl-2 overexpression prevents motoneuron cell body loss but not axonal degeneration in a mouse model of a neurodegenerative disease The Journal of Neuroscience. 15: 7727-7733. DOI: 10.1523/jneurosci.15-11-07727.1995 |
0.149 |
|
2014 |
Dirren E, Towne CL, Setola V, Redmond DE, Schneider BL, Aebischer P. Intracerebroventricular injection of adeno-associated virus 6 and 9 vectors for cell type-specific transgene expression in the spinal cord. Human Gene Therapy. 25: 109-20. PMID 24191919 DOI: 10.1089/hum.2013.021 |
0.148 |
|
2011 |
Towne C, Setola V, Schneider BL, Aebischer P. Neuroprotection by gene therapy targeting mutant SOD1 in individual pools of motor neurons does not translate into therapeutic benefit in fALS mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 274-83. PMID 21102563 DOI: 10.1038/mt.2010.260 |
0.147 |
|
1999 |
Xu XM, Zhang SX, Li H, Aebischer P, Bunge MB. Regrowth of axons into the distal spinal cord through a Schwann-cell-seeded mini-channel implanted into hemisected adult rat spinal cord. The European Journal of Neuroscience. 11: 1723-40. PMID 10215926 DOI: 10.1046/J.1460-9568.1999.00591.X |
0.147 |
|
2013 |
Coune PG, Craveiro M, Gaugler MN, Mlynárik V, Schneider BL, Aebischer P, Gruetter R. An in vivo ultrahigh field 14.1 T (1) H-MRS study on 6-OHDA and α-synuclein-based rat models of Parkinson's disease: GABA as an early disease marker. Nmr in Biomedicine. 26: 43-50. PMID 22711560 DOI: 10.1002/Nbm.2817 |
0.144 |
|
2001 |
Emborg ME, Deglon N, Leventhal L, Aebischer P, Kordower JH. Viral vector-mediated gene therapy for Parkinson's disease Clinical Neuroscience Research. 1: 496-506. DOI: 10.1016/S1566-2772(01)00027-5 |
0.143 |
|
2010 |
Duplan L, Bernard N, Casseron W, Dudley K, Thouvenot E, Honnorat J, Rogemond V, De Bovis B, Aebischer P, Marin P, Raoul C, Henderson CE, Pettmann B. Collapsin response mediator protein 4a (CRMP4a) is upregulated in motoneurons of mutant SOD1 mice and can trigger motoneuron axonal degeneration and cell death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 785-96. PMID 20071543 DOI: 10.1523/Jneurosci.5411-09.2010 |
0.142 |
|
1997 |
Kato AC, Aebischer P. Gene therapies fob the central nervous system | Thérapies géniques pour le système nerveux central Medecine Et Hygiene. 55: 1536-1538. |
0.142 |
|
2012 |
Ciron C, Lengacher S, Dusonchet J, Aebischer P, Schneider BL. Sustained expression of PGC-1α in the rat nigrostriatal system selectively impairs dopaminergic function. Human Molecular Genetics. 21: 1861-76. PMID 22246294 DOI: 10.1093/hmg/ddr618 |
0.141 |
|
2011 |
Coune PG, Bensadoun JC, Aebischer P, Schneider BL. Rab1A over-expression prevents Golgi apparatus fragmentation and partially corrects motor deficits in an alpha-synuclein based rat model of Parkinson's disease. Journal of Parkinson's Disease. 1: 373-87. PMID 23939344 DOI: 10.3233/JPD-2011-11058 |
0.14 |
|
2003 |
Kostic C, Chiodini F, Salmon P, Wiznerowicz M, Deglon N, Hornfeld D, Trono D, Aebischer P, Schorderet DF, Munier FL, Arsenijevic Y. Activity analysis of housekeeping promoters using self-inactivating lentiviral vector delivery into the mouse retina. Gene Therapy. 10: 818-21. PMID 12704422 DOI: 10.1038/Sj.Gt.3301948 |
0.14 |
|
2012 |
Oueslati A, Paleologou KE, Schneider BL, Aebischer P, Lashuel HA. Mimicking phosphorylation at serine 87 inhibits the aggregation of human α-synuclein and protects against its toxicity in a rat model of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 1536-44. PMID 22302797 DOI: 10.1523/Jneurosci.3784-11.2012 |
0.139 |
|
2002 |
Lo Bianco C, Ridet JL, Schneider BL, Deglon N, Aebischer P. alpha -Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 99: 10813-8. PMID 12122208 DOI: 10.1073/pnas.152339799 |
0.136 |
|
2008 |
Szulc J, Aebischer P. Conditional gene expression and knockdown using lentivirus vectors encoding shRNA. Methods in Molecular Biology (Clifton, N.J.). 434: 291-309. PMID 18470652 DOI: 10.1007/978-1-60327-248-3_18 |
0.136 |
|
2005 |
Colin E, Régulier E, Perrin V, Dürr A, Brice A, Aebischer P, Déglon N, Humbert S, Saudou F. Akt is altered in an animal model of Huntington's disease and in patients. The European Journal of Neuroscience. 21: 1478-88. PMID 15845076 DOI: 10.1111/J.1460-9568.2005.03985.X |
0.135 |
|
2016 |
Andrews MR, Soleman S, Cheah M, Tumbarello DA, Mason MR, Moloney E, Verhaagen J, Bensadoun JC, Schneider B, Aebischer P, Fawcett JW. Axonal Localization of Integrins in the CNS Is Neuronal Type and Age Dependent. Eneuro. 3. PMID 27570822 DOI: 10.1523/ENEURO.0029-16.2016 |
0.132 |
|
2004 |
Guillot S, Azzouz M, Déglon N, Zurn A, Aebischer P. Local GDNF expression mediated by lentiviral vector protects facial nerve motoneurons but not spinal motoneurons in SOD1(G93A) transgenic mice. Neurobiology of Disease. 16: 139-49. PMID 15207271 DOI: 10.1016/j.nbd.2004.01.017 |
0.13 |
|
2015 |
Mächler P, Wyss MT, Elsayed M, Stobart J, Gutierrez R, von Faber-Castell A, Kaelin V, Zuend M, San Martín A, Romero-Gómez I, Baeza-Lehnert F, Lengacher S, Schneider BL, Aebischer P, Magistretti PJ, et al. In Vivo Evidence for a Lactate Gradient from Astrocytes to Neurons. Cell Metabolism. PMID 26698914 DOI: 10.1016/J.Cmet.2015.10.010 |
0.13 |
|
2009 |
Chu Y, Dodiya H, Aebischer P, Olanow CW, Kordower JH. Alterations in lysosomal and proteasomal markers in Parkinson's disease: relationship to alpha-synuclein inclusions. Neurobiology of Disease. 35: 385-98. PMID 19505575 DOI: 10.1016/J.Nbd.2009.05.023 |
0.128 |
|
2008 |
Schneider B, Zufferey R, Aebischer P. Viral vectors, animal models and new therapies for Parkinson's disease. Parkinsonism & Related Disorders. 14: S169-71. PMID 18585946 DOI: 10.1016/j.parkreldis.2008.04.024 |
0.128 |
|
1991 |
Aebischer P, Goddard M, Bergman H, Wichmann T, DeLong MR. Treating Parkinson's disease with lesions of the subthalamic nucleus Science. 252: 133-134. PMID 2011750 DOI: 10.1126/science.2011750 |
0.127 |
|
2016 |
Brys I, Bobela W, Schneider BL, Aebischer P, Fuentes R. Spinal cord stimulation improves forelimb use in an alpha-synuclein animal model of Parkinson's disease. The International Journal of Neuroscience. 1-9. PMID 26856727 DOI: 10.3109/00207454.2016.1138296 |
0.127 |
|
2001 |
Arsenijevic Y, Villemure JG, Brunet JF, Bloch JJ, Déglon N, Kostic C, Zurn A, Aebischer P. Isolation of multipotent neural precursors residing in the cortex of the adult human brain. Experimental Neurology. 170: 48-62. PMID 11421583 DOI: 10.1006/exnr.2001.7691 |
0.126 |
|
2000 |
Schense JC, Bloch J, Aebischer P, Hubbell JA. Enzymatic incorporation of bioactive peptides into fibrin matrices enhances neurite extension Nature Biotechnology. 18: 415-419. PMID 10748522 DOI: 10.1038/74473 |
0.125 |
|
1986 |
AEBISCHER P, VALENTINI RF, WINN SR, KUNZ S, SASKEN H, GALLETTI PM. Regeneration of Transected Sciatic Nerves Through Semi-Permeable Nerve Guidance Channels Asaio Transactions. 32: 474-477. DOI: 10.1097/00002216-198609000-00017 |
0.122 |
|
2014 |
Aebischer P. Forword Industrial Scale Suspension Culture of Living Cells. v-vi. |
0.12 |
|
2015 |
Lathuiliere A, Laversenne V, Astolfo A, Stampanoni M, Bohrmann B, Schneider BL, Aebischer P. O1-05-03: Preventive anti-Aß passive immunization using a subcutaneous cellular implant lowers brain amyloid burden and tau pathology Alzheimer's & Dementia. 11: P136-P136. DOI: 10.1016/j.jalz.2015.07.053 |
0.119 |
|
1983 |
Schultz W, Ruffieux A, Aebischer P. The activity of pars compacta neurons of the monkey substantia nigra in relation to motor activation Experimental Brain Research. 51. DOI: 10.1007/BF00237874 |
0.118 |
|
2010 |
Towne C, Schneider BL, Kieran D, Redmond DE, Aebischer P. Efficient transduction of non-human primate motor neurons after intramuscular delivery of recombinant AAV serotype 6. Gene Therapy. 17: 141-6. PMID 19727139 DOI: 10.1038/gt.2009.119 |
0.118 |
|
2011 |
Dusonchet J, Kochubey O, Stafa K, Young SM, Zufferey R, Moore DJ, Schneider BL, Aebischer P. A rat model of progressive nigral neurodegeneration induced by the Parkinson's disease-associated G2019S mutation in LRRK2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 907-12. PMID 21248115 DOI: 10.1523/Jneurosci.5092-10.2011 |
0.117 |
|
2009 |
Perrin V, Dufour N, Raoul C, Hassig R, Brouillet E, Aebischer P, Luthi-Carter R, Déglon N. Implication of the JNK pathway in a rat model of Huntington's disease. Experimental Neurology. 215: 191-200. PMID 19022249 DOI: 10.1016/J.Expneurol.2008.10.008 |
0.115 |
|
2000 |
Tseng JL, Aebischer P. Encapsulated neural transplants Progress in Brain Research. 127: 189-202. PMID 11142028 DOI: 10.1016/S0079-6123(00)27010-6 |
0.115 |
|
2001 |
Bamber NI, Li H, Lu X, Oudega M, Aebischer P, Xu XM. Neurotrophins BDNF and NT-3 promote axonal re-entry into the distal host spinal cord through Schwann cell-seeded mini-channels European Journal of Neuroscience. 13: 257-268. PMID 11168530 DOI: 10.1111/j.1460-9568.2001.01387.x |
0.108 |
|
2007 |
Perrin V, Régulier E, Abbas-Terki T, Hassig R, Brouillet E, Aebischer P, Luthi-Carter R, Déglon N. Neuroprotection by Hsp104 and Hsp27 in lentiviral-based rat models of Huntington's disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 903-11. PMID 17375066 DOI: 10.1038/mt.sj.6300141 |
0.108 |
|
2006 |
Raoul C, Buhler E, Sadeghi C, Jacquier A, Aebischer P, Pettmann B, Henderson CE, Haase G. Chronic activation in presymptomatic amyotrophic lateral sclerosis (ALS) mice of a feedback loop involving Fas, Daxx, and FasL. Proceedings of the National Academy of Sciences of the United States of America. 103: 6007-12. PMID 16581901 DOI: 10.1073/pnas.0508774103 |
0.108 |
|
2008 |
Towne C, Raoul C, Schneider BL, Aebischer P. Systemic AAV6 delivery mediating RNA interference against SOD1: neuromuscular transduction does not alter disease progression in fALS mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1018-25. PMID 18414477 DOI: 10.1038/mt.2008.73 |
0.106 |
|
2009 |
Mastroeni R, Bensadoun JC, Charvin D, Aebischer P, Pujol A, Raoul C. Insulin-like growth factor-1 and neurotrophin-3 gene therapy prevents motor decline in an X-linked adrenoleukodystrophy mouse model. Annals of Neurology. 66: 117-22. PMID 19670442 DOI: 10.1002/ana.21677 |
0.105 |
|
2015 |
Bobela W, Aebischer P, Schneider BL. Αlpha-Synuclein as a Mediator in the Interplay between Aging and Parkinson's Disease. Biomolecules. 5: 2675-700. PMID 26501339 DOI: 10.3390/biom5042675 |
0.105 |
|
2000 |
Azzouz M, Hottinger A, Paterna JC, Zurn AD, Aebischer P, Büeler H. Increased motoneuron survival and improved neuromuscular function in transgenic ALS mice after intraspinal injection of an adeno-associated virus encoding Bcl-2 Human Molecular Genetics. 9: 803-811. PMID 10749988 |
0.104 |
|
2001 |
Aebischer P, Ridet JL. Recombinant proteins for neurodegenerative diseases: The delivery issue Trends in Neurosciences. 24: 533-540. PMID 11506887 DOI: 10.1016/S0166-2236(00)01899-3 |
0.104 |
|
2015 |
Askew C, Rochat C, Pan B, Asai Y, Ahmed H, Child E, Schneider BL, Aebischer P, Holt JR. Tmc gene therapy restores auditory function in deaf mice. Science Translational Medicine. 7: 295ra108. PMID 26157030 DOI: 10.1126/Scitranslmed.Aab1996 |
0.102 |
|
2002 |
Abbas-Terki T, Blanco-Bose W, Déglon N, Pralong W, Aebischer P. Lentiviral-mediated RNA interference. Human Gene Therapy. 13: 2197-201. PMID 12542850 DOI: 10.1089/104303402320987888 |
0.102 |
|
2002 |
Rinsch C, Dupraz P, Schneider BL, Déglon N, Maxwell PH, Ratcliffe PJ, Aebischer P. Delivery of erythropoietin by encapsulated myoblasts in a genetic model of severe anemia. Kidney International. 62: 1395-401. PMID 12234311 DOI: 10.1111/J.1523-1755.2002.Kid574.X |
0.101 |
|
2002 |
Boison D, Huber A, Padrun V, Déglon N, Aebischer P, Möhler H. Seizure suppression by adenosine-releasing cells is independent of seizure frequency. Epilepsia. 43: 788-96. PMID 12180995 DOI: 10.1046/J.1528-1157.2002.33001.X |
0.1 |
|
1997 |
Hottinger AF, Fine EG, Gurney ME, Zurn AD, Aebischer P. The copper chelator d-penicillamine delays onset of disease and extends survival in a transgenic mouse model of familial amyotrophic lateral sclerosis. The European Journal of Neuroscience. 9: 1548-51. PMID 9240414 DOI: 10.1111/j.1460-9568.1997.tb01511.x |
0.1 |
|
2009 |
Towne C, Aebischer P. Lentiviral and adeno-associated vector-based therapy for motor neuron disease through RNAi. Methods in Molecular Biology (Clifton, N.J.). 555: 87-108. PMID 19495690 DOI: 10.1007/978-1-60327-295-7_7 |
0.096 |
|
2009 |
Azeredo da Silveira S, Schneider BL, Cifuentes-Diaz C, Sage D, Abbas-Terki T, Iwatsubo T, Unser M, Aebischer P. Phosphorylation does not prompt, nor prevent, the formation of alpha-synuclein toxic species in a rat model of Parkinson's disease. Human Molecular Genetics. 18: 872-87. PMID 19074459 DOI: 10.1093/Hmg/Ddn417 |
0.095 |
|
2014 |
Kaplan A, Spiller KJ, Towne C, Kanning KC, Choe GT, Geber A, Akay T, Aebischer P, Henderson CE. Neuronal matrix metalloproteinase-9 is a determinant of selective neurodegeneration. Neuron. 81: 333-48. PMID 24462097 DOI: 10.1016/J.Neuron.2013.12.009 |
0.095 |
|
2013 |
Oueslati A, Schneider BL, Aebischer P, Lashuel HA. Polo-like kinase 2 regulates selective autophagic α-synuclein clearance and suppresses its toxicity in vivo. Proceedings of the National Academy of Sciences of the United States of America. 110: E3945-54. PMID 23983262 DOI: 10.1073/Pnas.1309991110 |
0.094 |
|
2007 |
Palfi S, Brouillet E, Jarraya B, Bloch J, Jan C, Shin M, Condé F, Li XJ, Aebischer P, Hantraye P, Déglon N. Expression of mutated huntingtin fragment in the putamen is sufficient to produce abnormal movement in non-human primates. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 1444-51. PMID 17505477 DOI: 10.1038/Sj.Mt.6300185 |
0.094 |
|
2001 |
Bensadoun JC, Pereira de Almeida L, Dréano M, Aebischer P, Déglon N. Neuroprotective effect of interleukin-6 and IL6/IL6R chimera in the quinolinic acid rat model of Huntington's syndrome European Journal of Neuroscience. 14: 1753-1761. PMID 11860469 DOI: 10.1046/j.0953-816X.2001.01802.x |
0.093 |
|
2012 |
Coune PG, Schneider BL, Aebischer P. Parkinson's disease: gene therapies. Cold Spring Harbor Perspectives in Medicine. 2: a009431. PMID 22474617 DOI: 10.1101/cshperspect.a009431 |
0.092 |
|
2013 |
Dassie E, Andrews MR, Bensadoun JC, Cacquevel M, Schneider BL, Aebischer P, Wouters FS, Richardson JC, Hussain I, Howlett DR, Spillantini MG, Fawcett JW. Focal expression of adeno-associated viral-mutant tau induces widespread impairment in an APP mouse model. Neurobiology of Aging. 34: 1355-68. PMID 23273572 DOI: 10.1016/J.Neurobiolaging.2012.11.011 |
0.092 |
|
2022 |
Rochat C, Bernard-Marissal N, Källstig E, Pradervand S, Perrin FE, Aebischer P, Raoul C, Schneider BL. Astrocyte-targeting RNA interference against mutated superoxide dismutase 1 induces motoneuron plasticity and protects fast-fatigable motor units in a mouse model of amyotrophic lateral sclerosis. Glia. PMID 34978340 DOI: 10.1002/glia.24140 |
0.091 |
|
2018 |
Lei H, Dirren E, Poitry-Yamate C, Schneider BL, Gruetter R, Aebischer P. Evolution of the neurochemical profiles in the G93A-SOD1 mouse model of amyotrophic lateral sclerosis. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X18756499. PMID 29400109 DOI: 10.1177/0271678X18756499 |
0.091 |
|
2009 |
McDonald A, Marone F, Hintermüller C, J-C Bensadoun, Aebischer P, Stampanoni M. High-throughput, high-resolution X-ray phase contrast tomographic microscopy for visualisation of soft tissue Journal of Physics: Conference Series. 186. DOI: 10.1088/1742-6596/186/1/012043 |
0.091 |
|
1999 |
Makohliso SA, Léonard D, Giovangrandi L, Mathieu HJ, Ilegems M, Aebischer P. Surface characterization of a biochip prototype for cell-based biosensor applications Langmuir. 15: 2940-2946. DOI: 10.1021/la980688h |
0.09 |
|
2006 |
Bensadoun JC, Aebischer P. Viral vectors as a tool to model and treat Parkinson's disease. Wiener Klinische Wochenschrift. 118: 568-70. PMID 17136329 DOI: 10.1007/s00508-006-0736-5 |
0.089 |
|
1999 |
Aebischer P, Hottinger AF, Deglon N. Cellular xenotransplantation [1] Nature Medicine. 5: 852. PMID 10426290 DOI: 10.1038/11271 |
0.089 |
|
2005 |
Raoul C, Abbas-Terki T, Bensadoun JC, Guillot S, Haase G, Szulc J, Henderson CE, Aebischer P. Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS. Nature Medicine. 11: 423-8. PMID 15768028 DOI: 10.1038/nm1207 |
0.088 |
|
2006 |
Raoul C, Barker SD, Aebischer P. Viral-based modelling and correction of neurodegenerative diseases by RNA interference. Gene Therapy. 13: 487-95. PMID 16319945 DOI: 10.1038/sj.gt.3302690 |
0.088 |
|
2004 |
Régulier E, Zala D, Aebischer P, Déglon N. Lentiviral-mediated gene transfer to model triplet repeat disorders. Methods in Molecular Biology (Clifton, N.J.). 277: 199-213. PMID 15201458 DOI: 10.1385/1-59259-804-8:199 |
0.085 |
|
2009 |
Blockeel C, Mock P, Verheyen G, Bouche N, Le Goff P, Heyman Y, Wrenzycki C, Höffmann K, Niemann H, Haentjens P, de Los Santos MJ, Fernandez-Sanchez M, Velasco M, Aebischer P, Devroey P, et al. An in vivo culture system for human embryos using an encapsulation technology: a pilot study. Human Reproduction (Oxford, England). 24: 790-6. PMID 19273881 DOI: 10.1093/humrep/dep005 |
0.083 |
|
2007 |
Wiznerowicz M, Jakobsson J, Szulc J, Liao S, Quazzola A, Beermann F, Aebischer P, Trono D. The Kruppel-associated box repressor domain can trigger de novo promoter methylation during mouse early embryogenesis. The Journal of Biological Chemistry. 282: 34535-41. PMID 17893143 DOI: 10.1074/Jbc.M705898200 |
0.082 |
|
2017 |
Zheng L, Bernard-Marissal N, Moullan N, D'Amico D, Auwerx J, Moore DJ, Knott G, Aebischer P, Schneider BL. Parkin functionally interacts with PGC-1α to preserve mitochondria and protect dopaminergic neurons. Human Molecular Genetics. PMID 28053050 DOI: 10.1093/hmg/ddw418 |
0.082 |
|
2012 |
Löw K, Aebischer P. Use of viral vectors to create animal models for Parkinson's disease. Neurobiology of Disease. 48: 189-201. PMID 22227451 DOI: 10.1016/j.nbd.2011.12.038 |
0.082 |
|
2010 |
Langou K, Moumen A, Pellegrino C, Aebischer J, Medina I, Aebischer P, Raoul C. AAV-mediated expression of wild-type and ALS-linked mutant VAPB selectively triggers death of motoneurons through a Ca2+-dependent ER-associated pathway. Journal of Neurochemistry. 114: 795-809. PMID 20477942 DOI: 10.1111/j.1471-4159.2010.06806.x |
0.082 |
|
2002 |
Déglon N, Aebischer P. Lentiviruses as vectors for CNS diseases Current Topics in Microbiology and Immunology. 261: 191-209. PMID 11892248 |
0.08 |
|
2008 |
Lo Bianco C, Shorter J, Régulier E, Lashuel H, Iwatsubo T, Lindquist S, Aebischer P. Hsp104 antagonizes alpha-synuclein aggregation and reduces dopaminergic degeneration in a rat model of Parkinson disease. The Journal of Clinical Investigation. 118: 3087-97. PMID 18704197 DOI: 10.1172/Jci35781 |
0.079 |
|
2010 |
Paleologou KE, Oueslati A, Shakked G, Rospigliosi CC, Kim HY, Lamberto GR, Fernandez CO, Schmid A, Chegini F, Gai WP, Chiappe D, Moniatte M, Schneider BL, Aebischer P, Eliezer D, et al. Phosphorylation at S87 is enhanced in synucleinopathies, inhibits alpha-synuclein oligomerization, and influences synuclein-membrane interactions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 3184-98. PMID 20203178 DOI: 10.1523/Jneurosci.5922-09.2010 |
0.079 |
|
2009 |
Towne C, Pertin M, Beggah AT, Aebischer P, Decosterd I. Recombinant adeno-associated virus serotype 6 (rAAV2/6)-mediated gene transfer to nociceptive neurons through different routes of delivery. Molecular Pain. 5: 52. PMID 19737386 DOI: 10.1186/1744-8069-5-52 |
0.078 |
|
2014 |
Dusonchet J, Li H, Guillily M, Liu M, Stafa K, Derada Troletti C, Boon JY, Saha S, Glauser L, Mamais A, Citro A, Youmans KL, Liu L, Schneider BL, Aebischer P, et al. A Parkinson's disease gene regulatory network identifies the signaling protein RGS2 as a modulator of LRRK2 activity and neuronal toxicity. Human Molecular Genetics. 23: 4887-905. PMID 24794857 DOI: 10.1093/Hmg/Ddu202 |
0.078 |
|
2015 |
Yang S, Cacquevel M, Saksida LM, Bussey TJ, Schneider BL, Aebischer P, Melani R, Pizzorusso T, Fawcett JW, Spillantini MG. Perineuronal net digestion with chondroitinase restores memory in mice with tau pathology. Experimental Neurology. 265: 48-58. PMID 25483398 DOI: 10.1016/J.Expneurol.2014.11.013 |
0.078 |
|
2009 |
Pertin M, Towne C, Beggah A, Aebischer P, Decosterd I. 229 EFFICACY AND SPECIFICITY OF RECOMBINANT ADENO-ASSOCIATED VIRUS SEROTYPE 6 MEDIATED GENE TRANSFER TO DRG NEURONS THROUGH DIFFERENT ROUTES OF DELIVERY European Journal of Pain. 13: S74. DOI: 10.1016/S1090-3801(09)60232-9 |
0.072 |
|
2011 |
Cacquevel M, Schneider B, Aebischer P, Aebi A, Colin P, Padrun V, Pidoux F. P1-035: Modelling Alzheimer's disease through Adeno-Associated Virus (AAV) vector gene delivery in the mouse brain Alzheimer's & Dementia. 7: S121-S122. DOI: 10.1016/j.jalz.2011.05.315 |
0.071 |
|
2013 |
Lathuilière A, Papin S, Cacquevel M, Paganetti P, Muhs A, Knott G, Schneider B, Aebischer P. Deciphering the role of tau in neurodegeneration using Adeno-Associated Viral (AAV) vectors to express human tau in the mouse forebrain Molecular Neurodegeneration. 8. DOI: 10.1186/1750-1326-8-S1-P27 |
0.071 |
|
2012 |
Mlynárik V, Cacquevel M, Sun-Reimer L, Janssens S, Cudalbu C, Lei H, Schneider BL, Aebischer P, Gruetter R. Proton and phosphorus magnetic resonance spectroscopy of a mouse model of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 31: S87-99. PMID 22451319 DOI: 10.3233/Jad-2012-112072 |
0.071 |
|
2008 |
Schneider BL, Gaugler MN, Aebischer P. Viral Vectors. A Potent Approach to Generate Genetic Models of Parkinson's Disease Parkinson's Disease. 269-284. DOI: 10.1016/B978-0-12-374028-1.00020-8 |
0.071 |
|
1998 |
Zurn AD, Tseng JL, Déglon N, Joseph JM, Aebischer P. A gene therapy approach for the treatment of amyotrophic lateral sclerosis and Parkinson's disease Advances in Pharmacology (San Diego, Calif.). 42: 929-931. PMID 9328050 DOI: 10.1016/S1054-3589(08)60899-6 |
0.068 |
|
2001 |
Kordower JH, Aebischer P. Gene therapy to the rescue in Parkinson's disease: Response from Kordower and Aebischer Trends in Pharmacological Sciences. 22: 105-106. PMID 11239562 DOI: 10.1016/S0165-6147(00)01637-0 |
0.068 |
|
2016 |
Ryu D, Mouchiroud L, Andreux PA, Katsyuba E, Moullan N, Nicolet-Dit-Félix AA, Williams EG, Jha P, Lo Sasso G, Huzard D, Aebischer P, Sandi C, Rinsch C, Auwerx J. Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents. Nature Medicine. PMID 27400265 DOI: 10.1038/Nm.4132 |
0.063 |
|
2003 |
Aebischer P, Pralong W. Gene therapy approaches for Parkinson's disease Journal of Neurochemistry. 85: 8-8. DOI: 10.1046/j.1471-4159.85.s2.8_3.x |
0.062 |
|
2011 |
Aebischer P. Marlowe in the movies Christopher Marlowe in Context. 316-324. DOI: 10.1017/CBO9781139060882.034 |
0.057 |
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2017 |
Bobela W, Nazeeruddin S, Knott G, Aebischer P, Schneider BL. Modulating the catalytic activity of AMPK has neuroprotective effects against α-synuclein toxicity. Molecular Neurodegeneration. 12: 80. PMID 29100525 DOI: 10.1186/s13024-017-0220-x |
0.056 |
|
2012 |
Pinzer BR, Cacquevel M, Modregger P, McDonald SA, Bensadoun JC, Thuering T, Aebischer P, Stampanoni M. Imaging brain amyloid deposition using grating-based differential phase contrast tomography. Neuroimage. 61: 1336-46. PMID 22450300 DOI: 10.1016/j.neuroimage.2012.03.029 |
0.056 |
|
1996 |
Sagot Y, Tan S, Hammang J, Aebischer P, Kato A. GDNF slows loss of motoneurons but not axonal degeneration or premature death of pmn/pmn mice The Journal of Neuroscience. 16: 2335-2341. DOI: 10.1523/jneurosci.16-07-02335.1996 |
0.056 |
|
1999 |
Fitting JW, Paillex R, Hirt L, Aebischer P, Schluep M. Sniff nasal pressure: A sensitive respiratory test to assess progression of amyotrophic lateral sclerosis Annals of Neurology. 46: 887-893. PMID 10589541 DOI: 10.1002/1531-8249(199912)46:6<887::AID-ANA11>3.0.CO;2-L |
0.054 |
|
2018 |
Singh A, Andreux P, Blanco-Bose W, Aebischer P, Auwerx J, Rinsch C. TRANSLATING UROLITHIN A BENEFITS ON MUSCLE MITOCHONDRIA TO HUMANS Innovation in Aging. 2: 92-93. DOI: 10.1093/Geroni/Igy023.351 |
0.053 |
|
2015 |
Dirren E, Aebischer J, Rochat C, Towne C, Schneider BL, Aebischer P. SOD1 silencing in motoneurons or glia rescues neuromuscular function in ALS mice. Annals of Clinical and Translational Neurology. 2: 167-84. PMID 25750921 DOI: 10.1002/acn3.162 |
0.05 |
|
2007 |
Aebischer P. Growing up with Shakespeare: The terry family memoirs Shakespeare and Childhood. 169-183. DOI: 10.1017/CBO9780511483493.011 |
0.049 |
|
2016 |
Bobela-Aebischer J, Rochat C, Bernard-Marissal N, Aebischer P, Schneider BL. 606. Use of a Bicistronic Vector to Silence SOD1 in Motoneurons and Astrocytes for the Treatment of Familial Amyotrophic Lateral Sclerosis Molecular Therapy. 24: S240. DOI: 10.1016/S1525-0016(16)33414-1 |
0.048 |
|
2015 |
Aebischer P. Shakespeare with a Difference: Dismembering and Remembering Titus Andronicus in Heiner Müller's and Brigitte Maria Mayer's Anatomie Titus A Concise Companion to the Study of Manuscripts, Printed Books, and the Production of Early Modern Texts: a Festschrift For Gordon Campbell. 322-345. DOI: 10.1002/9781118635261.ch16 |
0.048 |
|
2007 |
Aebischer P, Kato AC. Playng defense against Lou Gehrig's disease. Scientific American. 297: 86-93. PMID 17990828 |
0.045 |
|
2011 |
Aebischer P. Screening early modern drama: Beyond Shakespeare Screening Early Modern Drama: Beyond Shakespeare. 1-274. DOI: 10.1017/CBO9781139176194 |
0.045 |
|
1999 |
Aebischer P. GENE TRANSFER APPROACHES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES Biochemical Society Transactions. 27: A138-A138. DOI: 10.1042/bst027a138a |
0.043 |
|
2012 |
Lathuilière A, Cacquevel M, Schneider B, Aebischer P. P3-002: Overexpression of tau in the mouse forebrain using adeno-associated virus (AAV) leads to tau hyperphosphorylation, formation of neurofibrillary tangles and neurodegeneration Alzheimer's & Dementia. 8: P457-P457. DOI: 10.1016/j.jalz.2012.05.1220 |
0.043 |
|
2019 |
Andreux PA, Blanco-Bose W, Ryu D, Burdet F, Ibberson M, Aebischer P, Auwerx J, Singh A, Rinsch C. The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans. Nature Metabolism. 1: 595-603. PMID 32694802 DOI: 10.1038/s42255-019-0073-4 |
0.04 |
|
2004 |
Raoul C, Aebischer P. ALS, IGF-1 and gene therapy: 'It's never too late to mend' Gene Therapy. 11: 429-430. DOI: 10.1038/sj.gt.3302204 |
0.04 |
|
2015 |
Askew C, Rochat C, Pan B, Asai Y, Ahmed H, Child E, Schneider BL, Aebischer P, Holt JR. Tmc gene therapy restores auditory function in deaf mice Science Translational Medicine. 7. DOI: 10.1126/scitranslmed.aab1996 |
0.04 |
|
2011 |
Cacquevel M, Aebischer P, Aebi A, Colin P, Padrun V, Pidoux F, Schneider B. P1-036: Behavioral and neuropathological characterization of a viral-based model of amyloid pathology Alzheimer's & Dementia. 7: S122-S122. DOI: 10.1016/j.jalz.2011.05.316 |
0.039 |
|
2009 |
Barde I, Laurenti E, Verp S, Groner AC, Towne C, Padrun V, Aebischer P, Trumpp A, Trono D. Regulation of episomal gene expression by KRAB/KAP1-mediated histone modifications. Journal of Virology. 83: 5574-80. PMID 19279087 DOI: 10.1128/Jvi.00001-09 |
0.034 |
|
2021 |
Singh A, D'Amico D, Andreux PA, Dunngalvin G, Kern T, Blanco-Bose W, Auwerx J, Aebischer P, Rinsch C. Direct supplementation with Urolithin A overcomes limitations of dietary exposure and gut microbiome variability in healthy adults to achieve consistent levels across the population. European Journal of Clinical Nutrition. PMID 34117375 DOI: 10.1038/s41430-021-00950-1 |
0.031 |
|
2017 |
Singh A, Andreux P, Blanco-Bose W, Ryu D, Aebischer P, Auwerx J, Rinsch C. ORALLY ADMINISTERED UROLITHIN A IS SAFE AND MODULATES MUSCLE AND MITOCHONDRIAL BIOMARKERS IN ELDERLY Innovation in Aging. 1: 1223-1224. DOI: 10.1093/Geroni/Igx004.4446 |
0.03 |
|
2022 |
Singh A, D'Amico D, Andreux PA, Fouassier AM, Blanco-Bose W, Evans M, Aebischer P, Auwerx J, Rinsch C. Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults. Cell Reports. Medicine. 3: 100633. PMID 35584623 DOI: 10.1016/j.xcrm.2022.100633 |
0.029 |
|
2014 |
Escher G, Noukakis D, Aebischer P. Boosting higher education in Africa through shared massive open online courses (MOOCs) Education, Learning, Training: Critical Issues For Development. 195-215. DOI: 10.1163/9789004281158_011 |
0.029 |
|
2022 |
Liu S, D'Amico D, Shankland E, Bhayana S, Garcia JM, Aebischer P, Rinsch C, Singh A, Marcinek DJ. Effect of Urolithin A Supplementation on Muscle Endurance and Mitochondrial Health in Older Adults: A Randomized Clinical Trial. Jama Network Open. 5: e2144279. PMID 35050355 DOI: 10.1001/jamanetworkopen.2021.44279 |
0.025 |
|
2019 |
Andreux PA, Blanco-Bose W, Ryu D, Burdet F, Ibberson M, Aebischer P, Auwerx J, Singh A, Rinsch C. The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans Nature Metabolism. 1: 595-603. DOI: 10.1038/s42255-019-0073-4 |
0.025 |
|
2003 |
Aebischer P. Creative disability/disabled creativity in Henry Green's blindness (1926) Studies in the Novel. 35. |
0.024 |
|
2009 |
Aebischer P, Prince K. Performing early modern drama today Performing Early Modern Drama Today. 1-247. DOI: 10.1017/CBO9781139047975 |
0.024 |
|
2004 |
Zufferey R, Aebischer P. Salivary glands and gene therapy: the mouth waters. Gene Therapy. 11: 1425-6. PMID 15269715 DOI: 10.1038/sj.gt.3302321 |
0.022 |
|
1996 |
Heyd D, Aebischer P. Les facteurs neurotrophiques et leurs applications thérapeutiques potentielles MéDecine/Sciences. 12: 299. DOI: 10.4267/10608/732 |
0.022 |
|
2010 |
Aebischer P. Renaissance tragedy on film: Defying mainstream Shakespeare The Cambridge Companion to: English Renaissance Tragedy. 116-131. DOI: 10.1017/CCOL9780521519373.009 |
0.018 |
|
2012 |
Aebischer P. Philanthropy: The price of charity. Nature. 481: 260. PMID 22258589 DOI: 10.1038/481260a |
0.01 |
|
2009 |
Aebischer P. Shakespearean heritage and the preposterous "Contemporary Jacobean" film: Mike Figgis's hotel Shakespeare Quarterly. 60: 279-303. DOI: 10.1353/shq.0.0088 |
0.01 |
|
2008 |
Aebischer P. Gender Studies: Shakespeare, Sex, and Violence: Negotiating Masculinities in Branagh 's Henry V and Taymor's Titus A Concise Companion to Shakespeare On Screen. 112-132. DOI: 10.1002/9780470757659.ch6 |
0.01 |
|
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