Judes Poirier - Publications

Affiliations: 
McGill University, Montreal, QC, Canada 

111 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Miron J, Picard C, Frappier J, Dea D, Théroux L, Poirier J. TLR4 Gene Expression and Pro-Inflammatory Cytokines in Alzheimer's Disease and in Response to Hippocampal Deafferentation in Rodents. Journal of Alzheimer's Disease : Jad. PMID 29782315 DOI: 10.3233/JAD-171160  0.52
2018 Paquette M, Saavedra YGL, Poirier J, Théroux L, Dea D, Baass A, Dufour R. Loss-of-Function PCSK9 Mutations Are Not Associated With Alzheimer Disease. Journal of Geriatric Psychiatry and Neurology. 891988718764330. PMID 29562810 DOI: 10.1177/0891988718764330  0.52
2018 Picard C, Julien C, Frappier J, Miron J, Théroux L, Dea D, Breitner JCS, Poirier J. Alterations in cholesterol metabolism-related genes in sporadic Alzheimer's disease. Neurobiology of Aging. PMID 29503034 DOI: 10.1016/j.neurobiolaging.2018.01.018  0.52
2018 Pelleieux S, Picard C, Lamarre-Théroux L, Dea D, Leduc V, Tsantrizos YS, Poirier J. Isoprenoids and tau pathology in sporadic Alzheimer's disease. Neurobiology of Aging. 65: 132-139. PMID 29476987 DOI: 10.1016/j.neurobiolaging.2018.01.012  0.52
2018 Miron J, Picard C, Nilsson N, Frappier J, Dea D, Théroux L, Poirier J. CDK5RAP2 gene and tau pathophysiology in late-onset sporadic Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29360470 DOI: 10.1016/j.jalz.2017.12.004  0.52
2018 Nyarko JNK, Quartey MO, Pennington PR, Heistad RM, Dea D, Poirier J, Baker GB, Mousseau DD. Profiles of β-amyloid peptides and key secretases in brain autopsy samples differ with sex and APOE ε4 status: impact for risk and progression of Alzheimer disease. Neuroscience. PMID 29331531 DOI: 10.1016/j.neuroscience.2018.01.005  0.52
2017 Parent MJ, Zimmer ER, Shin M, Kang MS, Fonov VS, Mathieu A, Aliaga A, Kostikov A, Do Carmo S, Dea D, Poirier J, Soucy JP, Gauthier S, Cuello AC, Rosa-Neto P. Multimodal imaging in rat model recapitulates Alzheimer's Disease biomarkers abnormalities. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29097597 DOI: 10.1523/JNEUROSCI.1346-17.2017  0.52
2016 De Beaumont L, Pelleieux S, Lamarre-Théroux L, Dea D, Poirier J. Butyrylcholinesterase K and Apolipoprotein E-ɛ4 Reduce the Age of Onset of Alzheimer's Disease, Accelerate Cognitive Decline, and Modulate Donepezil Response in Mild Cognitively Impaired Subjects. Journal of Alzheimer's Disease : Jad. PMID 27567841 DOI: 10.3233/JAD-160373  0.52
2016 Gosselin N, De Beaumont L, Gagnon K, Baril AA, Mongrain V, Blais H, Montplaisir J, Gagnon JF, Pelleieux S, Poirier J, Carrier J. BDNF Val66Met Polymorphism Interacts with Sleep Consolidation to Predict Ability to Create New Declarative Memories. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 8390-8. PMID 27511011 DOI: 10.1523/JNEUROSCI.4432-15.2016  0.52
2016 Schoemaker D, Poirier J, Escobar S, Gauthier S, Pruessner J. Selective familiarity deficits in otherwise cognitively intact aging individuals with genetic risk for Alzheimer's disease. Alzheimer's & Dementia (Amsterdam, Netherlands). 2: 132-9. PMID 27239534 DOI: 10.1016/j.dadm.2015.11.007  0.52
2016 Leduc V, Bourque L, Poirier J, Dufour R. Role of rs3846662 and HMGCR alternative splicing in statin efficacy and baseline lipid levels in familial hypercholesterolemia. Pharmacogenetics and Genomics. 26: 1-11. PMID 26466344 DOI: 10.1097/FPC.0000000000000178  0.52
2015 Benedet AL, Labbe A, Lemay P, Zimmer ER, Pascoal TA, Leuzy A, Mathotaarachchi S, Mohades S, Shin M, Dionne-Laporte A, Beaudry T, Picard C, Gauthier S, Poirier J, Rouleau G, et al. Epistasis analysis links immune cascades and cerebral amyloidosis. Journal of Neuroinflammation. 12: 227. PMID 26626881 DOI: 10.1186/s12974-015-0436-z  0.52
2015 Leduc V, Théroux L, Dea D, Dufour R, Poirier J. Effects of rs3846662 Variants on HMGCR mRNA and Protein Levels and on Markers of Alzheimer's Disease Pathology. Journal of Molecular Neuroscience : Mn. PMID 26541602 DOI: 10.1007/s12031-015-0666-7  0.52
2015 Larson-Dupuis C, Chamard É, Falardeau V, Frasnelli J, Beaulieu C, Poirier J, Carrier J, Lassonde M, Théoret H, Bacon BA, De Beaumont L. Impact of BDNF Val66Met polymorphism on olfactory functions of female concussed athletes. Brain Injury. 1-8. PMID 25950261 DOI: 10.3109/02699052.2015.1016452  0.52
2015 Leduc V, De Beaumont L, Théroux L, Dea D, Aisen P, Petersen RC, Dufour R, Poirier J. HMGCR is a genetic modifier for risk, age of onset and MCI conversion to Alzheimer's disease in a three cohorts study. Molecular Psychiatry. 20: 867-73. PMID 25023145 DOI: 10.1038/mp.2014.81  0.52
2014 Poirier J, Miron J, Picard C, Gormley P, Théroux L, Breitner J, Dea D. Apolipoprotein E and lipid homeostasis in the etiology and treatment of sporadic Alzheimer's disease. Neurobiology of Aging. 35: S3-10. PMID 24973118 DOI: 10.1016/j.neurobiolaging.2014.03.037  0.52
2014 De Schutter JW, Park J, Leung CY, Gormley P, Lin YS, Hu Z, Berghuis AM, Poirier J, Tsantrizos YS. Multistage screening reveals chameleon ligands of the human farnesyl pyrophosphate synthase: implications to drug discovery for neurodegenerative diseases. Journal of Medicinal Chemistry. 57: 5764-76. PMID 24911527 DOI: 10.1021/jm500629e  0.52
2014 Jasmin SB, Pearson V, Lalonde D, Domenger D, Théroux L, Poirier J. Differential regulation of ABCA1 and ABCG1 gene expressions in the remodeling mouse hippocampus after entorhinal cortex lesion and liver-X receptor agonist treatment. Brain Research. 1562: 39-51. PMID 24661912 DOI: 10.1016/j.brainres.2014.03.016  0.52
2014 Poirier J, Miron J, Picard C. Pharmacogenomic Approaches to the Treatment of Sporadic Alzheimer Disease using Cholinomimetic Agents Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease: Fifth Edition. 51-62. DOI: 10.1016/B978-0-12-410529-4.00004-8  0.52
2013 De Beaumont L, Tremblay S, Henry LC, Poirier J, Lassonde M, Théoret H. Motor system alterations in retired former athletes: the role of aging and concussion history. Bmc Neurology. 13: 109. PMID 23972282 DOI: 10.1186/1471-2377-13-109  0.52
2013 De Beaumont L, Fiocco AJ, Quesnel G, Lupien S, Poirier J. Altered declarative memory in introverted middle-aged adults carrying the BDNF val66met allele. Behavioural Brain Research. 253: 152-6. PMID 23835043 DOI: 10.1016/j.bbr.2013.07.002  0.52
2013 Tremblay S, De Beaumont L, Henry LC, Boulanger Y, Evans AC, Bourgouin P, Poirier J, Théoret H, Lassonde M. Sports concussions and aging: a neuroimaging investigation. Cerebral Cortex (New York, N.Y. : 1991). 23: 1159-66. PMID 22581847 DOI: 10.1093/cercor/bhs102  0.52
2012 Domenger D, Dea D, Theroux L, Moquin L, Gratton A, Poirier J. The MPTP neurotoxic lesion model of Parkinson's disease activates the apolipoprotein E cascade in the mouse brain. Experimental Neurology. 233: 513-22. PMID 22155743 DOI: 10.1016/j.expneurol.2011.11.031  0.52
2012 De Beaumont L, Tremblay S, Poirier J, Lassonde M, Théoret H. Altered bidirectional plasticity and reduced implicit motor learning in concussed athletes. Cerebral Cortex (New York, N.Y. : 1991). 22: 112-21. PMID 21572090 DOI: 10.1093/cercor/bhr096  0.52
2011 Henderson ST, Poirier J. Pharmacogenetic analysis of the effects of polymorphisms in APOE, IDE and IL1B on a ketone body based therapeutic on cognition in mild to moderate Alzheimer's disease; a randomized, double-blind, placebo-controlled study. Bmc Medical Genetics. 12: 137. PMID 21992747 DOI: 10.1186/1471-2350-12-137  0.52
2011 Poirier J, Semple H, Davies J, Lapointe R, Dziwenka M, Hiltz M, Mujibi D. Double-blind, vehicle-controlled randomized twelve-month neurodevelopmental toxicity study of common aluminum salts in the rat. Neuroscience. 193: 338-62. PMID 21699960 DOI: 10.1016/j.neuroscience.2011.05.008  0.52
2011 Leduc V, Legault V, Dea D, Poirier J. Normalization of gene expression using SYBR green qPCR: a case for paraoxonase 1 and 2 in Alzheimer's disease brains. Journal of Neuroscience Methods. 200: 14-9. PMID 21672555 DOI: 10.1016/j.jneumeth.2011.05.026  0.52
2011 Leduc V, Domenger D, De Beaumont L, Lalonde D, Bélanger-Jasmin S, Poirier J. Function and comorbidities of apolipoprotein e in Alzheimer's disease. International Journal of Alzheimer's Disease. 2011: 974361. PMID 21559182 DOI: 10.4061/2011/974361  0.52
2010 Leduc V, Jasmin-Bélanger S, Poirier J. APOE and cholesterol homeostasis in Alzheimer's disease. Trends in Molecular Medicine. 16: 469-77. PMID 20817608 DOI: 10.1016/j.molmed.2010.07.008  0.52
2009 Leduc V, Théroux L, Dea D, Robitaille Y, Poirier J. Involvement of paraoxonase 1 genetic variants in Alzheimer's disease neuropathology. The European Journal of Neuroscience. 30: 1823-30. PMID 19863653 DOI: 10.1111/j.1460-9568.2009.06983.x  0.52
2009 Gauthier S, Poirier J. Commentary on "A roadmap for the prevention of dementia II. Leon Thal Symposium 2008." Who may benefit from disease-modifying studies in Alzheimer's disease? Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 5: 147-8. PMID 19328447 DOI: 10.1016/j.jalz.2009.01.007  0.52
2009 Freemantle E, Vandal M, Tremblay-Mercier J, Plourde M, Poirier J, Cunnane SC. Metabolic response to a ketogenic breakfast in the healthy elderly Journal of Nutrition, Health and Aging. 13: 293-298. PMID 19300863 DOI: 10.1007/s12603-009-0026-9  0.52
2009 Rajah MN, Bastianetto S, Bromley-Brits K, Cools R, D'Esposito M, Grady CL, Poirier J, Quirion R, Raz N, Rogaeva E, Song W, Pruessner J. Biological changes associated with healthy versus pathological aging: a symposium review. Ageing Research Reviews. 8: 140-6. PMID 19274854 DOI: 10.1016/j.arr.2009.01.003  0.52
2009 Fiocco AJ, Nair NPV, Schwartz G, Ng Ying Kin F, Joober R, Poirier J, Lupien SJ. Influence of genetic polymorphisms in the apolipoprotein (APOE) and the butyrylcholinesterase (BCHE) gene on stress markers in older adults: A 3-year study Neurobiology of Aging. 30: 1001-1005. PMID 17996334 DOI: 10.1016/j.neurobiolaging.2007.09.008  0.52
2008 Poirier J. Apolipoprotein E represents a potent gene-based therapeutic target for the treatment of sporadic Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 4: S91-7. PMID 18632009 DOI: 10.1016/j.jalz.2007.11.012  0.52
2008 Gauthier S, Poirier J. Current and future management of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 4: S48-50. PMID 18632000 DOI: 10.1016/j.jalz.2007.11.010  0.52
2008 Khachaturian ZS, Petersen RC, Gauthier S, Buckholtz N, Corey-Bloom JP, Evans B, Fillit H, Foster N, Greenberg B, Grundman M, Sano M, Simpkins J, Schneider LS, Weiner MW, Galasko D, ... ... Poirier J, et al. A roadmap for the prevention of dementia: the inaugural Leon Thal Symposium. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 4: 156-63. PMID 18631960 DOI: 10.1016/j.jalz.2008.03.005  0.52
2008 Fiocco AJ, Poirier J, Joober R, Nair NP, Lupien SJ. Acute and long-term associations between ApoE genetic polymorphism, cortisol levels, and declarative memory performance in older adults. Psychoneuroendocrinology. 33: 625-33. PMID 18374494 DOI: 10.1016/j.psyneuen.2008.02.002  0.52
2008 Leduc V, Poirier J. Polymorphisms at the paraoxonase 1 L55M and Q192R loci affect the pathophysiology of Alzheimer's disease: emphasis on the cholinergic system and beta-amyloid levels. Neuro-Degenerative Diseases. 5: 225-7. PMID 18322397 DOI: 10.1159/000113709  0.52
2008 Burgess BL, Parkinson PF, Racke MM, Hirsch-Reinshagen V, Fan J, Wong C, Stukas S, Theroux L, Chan JY, Donkin J, Wilkinson A, Balik D, Christie B, Poirier J, Lütjohann D, et al. ABCG1 influences the brain cholesterol biosynthetic pathway but does not affect amyloid precursor protein or apolipoprotein E metabolism in vivo. Journal of Lipid Research. 49: 1254-67. PMID 18314463 DOI: 10.1194/jlr.M700481-JLR200  0.52
2008 Aleong R, Blain JF, Poirier J. Pro-inflammatory cytokines modulate glial apolipoprotein E secretion. Current Alzheimer Research. 5: 33-7. PMID 18288929 DOI: 10.2174/156720508783884666  0.52
2008 Poirier J, Gauthier S. Pharmacogenomics and the treatment of sporadic Alzheimer's disease: A decade of progress Current Pharmacogenomics and Personalized Medicine. 6: 63-76. DOI: 10.2174/187569208784017494  0.52
2007 Fiocco AJ, Joober R, Poirier J, Lupien S. Polymorphism of the 5-HT(2A) receptor gene: association with stress-related indices in healthy middle-aged adults. Frontiers in Behavioral Neuroscience. 1: 3. PMID 18958185 DOI: 10.3389/neuro.08.003.2007  0.52
2007 Petit-Turcotte C, Aumont N, Blain JF, Poirier J. Apolipoprotein E receptors and amyloid expression are modulated in an apolipoprotein E-dependent fashion in response to hippocampal deafferentation in rodent. Neuroscience. 150: 58-63. PMID 17935896 DOI: 10.1016/j.neuroscience.2007.05.021  0.52
2007 Poirier J. Apolipoprotein E: A potent gene-based therapeutic target for the treatment of sporadic Alzheimer's disease Pharmacological Mechanisms in Alzheimer's Therapeutics. 212-222. DOI: 10.1007/978-0-387-71522-3_13  0.52
2006 Blain JF, Aumont N, Théroux L, Dea D, Poirier J. A polymorphism in lipoprotein lipase affects the severity of Alzheimer's disease pathophysiology. The European Journal of Neuroscience. 24: 1245-51. PMID 16965549 DOI: 10.1111/j.1460-9568.2006.05007.x  0.52
2006 Kar S, Poirier J, Guevara J, Dea D, Hawkes C, Robitaille Y, Quirion R. Cellular distribution of insulin-like growth factor-II/mannose-6-phosphate receptor in normal human brain and its alteration in Alzheimer's disease pathology. Neurobiology of Aging. 27: 199-210. PMID 16399207 DOI: 10.1016/j.neurobiolaging.2005.03.005  0.52
2006 Blain JF, Sullivan PM, Poirier J. A deficit in astroglial organization causes the impaired reactive sprouting in human apolipoprotein E4 targeted replacement mice. Neurobiology of Disease. 21: 505-14. PMID 16171999 DOI: 10.1016/j.nbd.2005.08.010  0.52
2005 Hirsch-Reinshagen V, Maia LF, Burgess BL, Blain JF, Naus KE, McIsaac SA, Parkinson PF, Chan JY, Tansley GH, Hayden MR, Poirier J, Van Nostrand W, Wellington CL. The absence of ABCA1 decreases soluble ApoE levels but does not diminish amyloid deposition in two murine models of Alzheimer disease. The Journal of Biological Chemistry. 280: 43243-56. PMID 16207707 DOI: 10.1074/jbc.M508781200  0.52
2005 Champagne D, Rochford J, Poirier J. Effect of apolipoprotein E deficiency on reactive sprouting in the dentate gyrus of the hippocampus following entorhinal cortex lesion: role of the astroglial response. Experimental Neurology. 194: 31-42. PMID 15899241 DOI: 10.1016/j.expneurol.2005.01.016  0.52
2005 Gaudreault SB, Blain JF, Gratton JP, Poirier J. A role for caveolin-1 in post-injury reactive neuronal plasticity. Journal of Neurochemistry. 92: 831-9. PMID 15686485 DOI: 10.1111/j.1471-4159.2004.02917.x  0.52
2005 Poirier J. Apolipoprotein E, cholesterol transport and synthesis in sporadic Alzheimer's disease. Neurobiology of Aging. 26: 355-61. PMID 15639314 DOI: 10.1016/j.neurobiolaging.2004.09.003  0.52
2005 Petit-Turcotte C, Aumont N, Beffert U, Dea D, Herz J, Poirier J. The apoE receptor apoER2 is involved in the maintenance of efficient synaptic plasticity. Neurobiology of Aging. 26: 195-206. PMID 15582748 DOI: 10.1016/j.neurobiolaging.2004.04.007  0.52
2004 Blain JF, Poirier J. Cholesterol homeostasis and the pathophysiology of Alzheimer's disease. Expert Review of Neurotherapeutics. 4: 823-9. PMID 15853509 DOI: 10.1586/14737175.4.5.823  0.52
2004 Blain JF, Poirier J. Could lipoprotein lipase play a role in Alzheimer's disease? Thescientificworldjournal. 4: 531-5. PMID 15311328 DOI: 10.1100/tsw.2004.111  0.52
2004 Gaudreault SB, Dea D, Poirier J. Increased caveolin-1 expression in Alzheimer's disease brain. Neurobiology of Aging. 25: 753-9. PMID 15165700 DOI: 10.1016/j.neurobiolaging.2003.07.004  0.52
2004 Evans RM, Hui S, Perkins A, Lahiri DK, Poirier J, Farlow MR. Cholesterol and APOE genotype interact to influence Alzheimer disease progression. Neurology. 62: 1869-71. PMID 15159498  0.52
2004 Blain JF, Paradis E, Gaudreault SB, Champagne D, Richard D, Poirier J. A role for lipoprotein lipase during synaptic remodeling in the adult mouse brain. Neurobiology of Disease. 15: 510-9. PMID 15056458 DOI: 10.1016/j.nbd.2003.12.001  0.52
2004 Gaudreault SB, Chabot C, Gratton JP, Poirier J. The caveolin scaffolding domain modifies 2-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor binding properties by inhibiting phospholipase A2 activity. The Journal of Biological Chemistry. 279: 356-62. PMID 14561756 DOI: 10.1074/jbc.M304777200  0.52
2003 Aleong R, Aumont N, Dea D, Poirier J. Non-steroidal anti-inflammatory drugs mediate increased in vitro glial expression of apolipoprotein E protein. The European Journal of Neuroscience. 18: 1428-38. PMID 14511323 DOI: 10.1046/j.1460-9568.2003.02869.x  0.52
2003 Champagne D, Pearson D, Dea D, Rochford J, Poirier J. The cholesterol-lowering drug probucol increases apolipoprotein E production in the hippocampus of aged rats: implications for Alzheimer's disease. Neuroscience. 121: 99-110. PMID 12946703 DOI: 10.1016/S0306-4522(03)00361-0  0.52
2003 Poirier J. Apolipoprotein E and cholesterol metabolism in the pathogenesis and treatment of Alzheimer's disease. Trends in Molecular Medicine. 9: 94-101. PMID 12657430 DOI: 10.1016/S1471-4914(03)00007-8  0.52
2002 de Leon MJ, Segal S, Tarshish CY, DeSanti S, Zinkowski R, Mehta PD, Convit A, Caraos C, Rusinek H, Tsui W, Saint Louis LA, DeBernardis J, Kerkman D, Qadri F, Gary A, ... ... Poirier J, et al. Longitudinal cerebrospinal fluid tau load increases in mild cognitive impairment. Neuroscience Letters. 333: 183-6. PMID 12429378 DOI: 10.1016/S0304-3940(02)01038-8  0.52
2002 Champagne D, Dupuy JB, Rochford J, Poirier J. Apolipoprotein E knockout mice display procedural deficits in the Morris water maze: analysis of learning strategies in three versions of the task. Neuroscience. 114: 641-54. PMID 12220566 DOI: 10.1016/S0306-4522(02)00313-5  0.52
2002 Poirier J. Evidence that the clinical effects of cholinesterase inhibitors are related to potency and targeting of action International Journal of Clinical Practice, Supplement. 6-19. PMID 12139368  0.52
2002 Zetterberg H, Palmér M, Ricksten A, Poirier J, Palmqvist L, Rymo L, Zafiropoulos A, Arvanitis DA, Spandidos DA, Blennow K. Influence of the apolipoprotein E epsilon4 allele on human embryonic development. Neuroscience Letters. 324: 189-92. PMID 12009520 DOI: 10.1016/S0304-3940(02)00198-2  0.52
2002 Danik M, Poirier J. Chapter 4 Apolipoprotein E and lipid mobilization in neuronal membrane remodeling and its relevance to Alzheimer's disease New Comprehensive Biochemistry. 35: 53-66.  0.52
2001 Petit-Turcotte C, Stohl SM, Beffert U, Cohn JS, Aumont N, Tremblay M, Dea D, Yang L, Poirier J, Shachter NS. Apolipoprotein C-I expression in the brain in Alzheimer's disease. Neurobiology of Disease. 8: 953-63. PMID 11741391 DOI: 10.1006/nbdi.2001.0441  0.52
2001 De Leon MJ, Convit A, Wolf OT, Tarshish CY, DeSanti S, Rusinek H, Tsui W, Kandil E, Scherer AJ, Roche A, Imossi A, Thorn E, Bobinski M, Caraos C, Lesbre P, ... ... Poirier J, et al. Prediction of cognitive decline in normal elderly subjects with 2-[18F]fluoro-2-deoxy-D-glucose/positron-emission tomography (FDG/PET) Proceedings of the National Academy of Sciences of the United States of America. 98: 10966-10971. PMID 11526211 DOI: 10.1073/pnas.191044198  0.52
2001 Vaucher E, Aumont N, Pearson D, Rowe W, Poirier J, Kar S. Amyloid beta peptide levels and its effects on hippocampal acetylcholine release in aged, cognitively-impaired and -unimpaired rats. Journal of Chemical Neuroanatomy. 21: 323-9. PMID 11429273 DOI: 10.1016/S0891-0618(01)00120-X  0.52
2001 Ramassamy C, Krzywkowski P, Averill D, Lussier-Cacan S, Theroux L, Christen Y, Davignon J, Poirier J. Impact of apoE deficiency on oxidative insults and antioxidant levels in the brain Molecular Brain Research. 86: 76-83. PMID 11165374 DOI: 10.1016/S0169-328X(00)00268-0  0.52
2001 Lehmann DJ, Wiebusch H, Marshall SE, Johnston C, Warden DR, Morgan K, Schappert K, Poirier J, Xuereb J, Kalsheker N, Welsh KI, Smith AD. HLA class I, II & III genes in confirmed late-onset Alzheimer's disease. Neurobiology of Aging. 22: 71-7. PMID 11164278 DOI: 10.1016/S0197-4580(00)00180-9  0.52
2001 Valastro B, Ghribi O, Poirier J, Krzywkowski P, Massicotte G. AMPA receptor regulation and LTP in the hippocampus of young and aged apolipoprotein E-deficient mice. Neurobiology of Aging. 22: 9-15. PMID 11164271 DOI: 10.1016/S0197-4580(00)00177-9  0.52
2001 Poirier J. High blood pressure and apolipoprotein E4: A true synergistic effect on late-life cognitive function Stroke. 32: 2888-2889.  0.52
2000 Poirier J. Apolipoprotein E and Alzheimer's disease a role in amyloid catabolism Annals of the New York Academy of Sciences. 924: 81-90. PMID 11193807  0.52
2000 Patrick CB, Krzywkowski P, Ramassamy C, Poirier J, Rapoport SI, Murphy EJ. Phospholipase A2 activity is decreased selectively in the hippocampus of aged apolipoprotein E deficient mice. Neuroscience Letters. 288: 211-4. PMID 10889345 DOI: 10.1016/S0304-3940(00)01240-4  0.52
2000 Bastianetto S, Ramassamy C, Doré S, Christen Y, Poirier J, Quirion R. The Ginkgo biloba extract (EGb 761) protects hippocampal neurons against cell death induced by beta-amyloid. The European Journal of Neuroscience. 12: 1882-90. PMID 10886329 DOI: 10.1046/j.1460-9568.2000.00069.x  0.52
2000 Poirier JL, Čapek R, De Koninck Y. Differential progression of Dark Neuron and Fluoro-Jade labelling in the rat hippocampus following pilocarpine-induced status epilepticus Neuroscience. 97: 59-68. PMID 10771339 DOI: 10.1016/S0306-4522(00)00026-9  0.52
2000 Ramassamy C, Averill D, Beffert U, Theroux L, Lussier-Cacan S, Cohn JS, Christen Y, Schoofs A, Davignon J, Poirier J. Oxidative insults are associated with apolipoprotein E genotype in Alzheimer's disease brain. Neurobiology of Disease. 7: 23-37. PMID 10671320 DOI: 10.1006/nbdi.1999.0273  0.52
1999 Danik M, Champagne D, Petit-Turcotte C, Beffert U, Poirier J. Brain lipoprotein metabolism and its relation to neurodegenerative disease. Critical Reviews in Neurobiology. 13: 357-407. PMID 11028681  0.52
1999 Poirier J. Apolipoprotein E: A pharmacogenetic target for the treatment of Alzheimer's disease Molecular Diagnosis. 4: 335-341. PMID 10671644 DOI: 10.1016/S1084-8592(99)80010-1  0.52
1999 Bretsky PM, Buckwalter JG, Seeman TE, Miller CA, Poirier J, Schellenberg GD, Finch CE, Henderson VW. Evidence for an interaction between apolipoprotein E genotype, gender, and Alzheimer disease. Alzheimer Disease and Associated Disorders. 13: 216-21. PMID 10609670  0.52
1999 Beffert U, Cohn JS, Petit-Turcotte C, Tremblay M, Aumont N, Ramassamy C, Davignon J, Poirier J. Apolipoprotein E and beta-amyloid levels in the hippocampus and frontal cortex of Alzheimer's disease subjects are disease-related and apolipoprotein E genotype dependent. Brain Research. 843: 87-94. PMID 10528114 DOI: 10.1016/S0006-8993(99)01894-6  0.52
1999 Ramassamy C, Averill D, Beffert U, Bastianetto S, Theroux L, Lussier-Cacan S, Cohn JS, Christen Y, Davignon J, Quirion R, Poirier J. Oxidative damage and protection by antioxidants in the frontal cortex of Alzheimer's disease is related to the apolipoprotein E genotype. Free Radical Biology & Medicine. 27: 544-53. PMID 10490274 DOI: 10.1016/S0891-5849(99)00102-1  0.52
1999 Krzywkowski P, Ghribi O, Gagné J, Chabot C, Kar S, Rochford J, Massicotte G, Poirier J. Cholinergic systems and long-term potentiation in memory-impaired apolipoprotein E-deficient mice. Neuroscience. 92: 1273-86. PMID 10426483 DOI: 10.1016/S0306-4522(99)00061-5  0.52
1999 Terrisse L, Séguin D, Bertrand P, Poirier J, Milne R, Rassart E. Modulation of apolipoprotein D and apolipoprotein E expression in rat hippocampus after entorhinal cortex lesion. Brain Research. Molecular Brain Research. 70: 26-35. PMID 10381540 DOI: 10.1016/S0169-328X(99)00123-0  0.52
1999 Beffert U, Aumont N, Dea D, Lussier-Cacan S, Davignon J, Poirier J. Apolipoprotein E isoform-specific reduction of extracellular amyloid in neuronal cultures. Brain Research. Molecular Brain Research. 68: 181-5. PMID 10320795 DOI: 10.1016/S0169-328X(99)00073-X  0.52
1999 Poirier J. Apolipoprotein E4, cholinergic integrity and the pharmacogenetics of Alzheimer's disease Journal of Psychiatry and Neuroscience. 24: 147-153. PMID 10212558  0.52
1999 Wiebusch H, Poirier J, Sévigny P, Schappert K. Further evidence for a synergistic association between APOE ε4 and BCHE-K in confirmed Alzheimer's disease Human Genetics. 104: 158-163. PMID 10190327 DOI: 10.1007/s004390050929  0.52
1999 Bastianetto S, Ramassamy C, Poirier J, Quirion R. Dehydroepiandrosterone (DHEA) protects hippocampal cells from oxidative stress-induced damage. Brain Research. Molecular Brain Research. 66: 35-41. PMID 10095075 DOI: 10.1016/S0169-328X(99)00002-9  0.52
1999 Beffert U, Arguin C, Poirier J. The polymorphism in exon 3 of the low density lipoprotein receptor-related protein gene is weakly associated with Alzheimer's disease. Neuroscience Letters. 259: 29-32. PMID 10027548 DOI: 10.1016/S0304-3940(98)00888-X  0.52
1998 Beffert U, Poirier J. ApoE associated with lipid has a reduced capacity to inhibit beta-amyloid fibril formation. Neuroreport. 9: 3321-3. PMID 9831470  0.52
1998 Terrisse L, Poirier J, Bertrand P, Merched A, Visvikis S, Siest G, Milne R, Rassart E. Increased levels of apolipoprotein D in cerebrospinal fluid and hippocampus of Alzheimer's patients. Journal of Neurochemistry. 71: 1643-50. PMID 9751198  0.52
1998 Lambert JC, Berr C, Pasquier F, Delacourte A, Frigard B, Cottel D, Pérez-Tur J, Mouroux V, Mohr M, Cécyre D, Galasko D, Lendon C, Poirier J, Hardy J, Mann D, et al. Pronounced impact of Th1/E47cs mutation compared with -491 AT mutation on neural APOE gene expression and risk of developing Alzheimer's disease. Human Molecular Genetics. 7: 1511-6. PMID 9700208 DOI: 10.1093/hmg/7.9.1511  0.52
1998 Itzhaki RF, Lin WR, Wilcock GK, Faragher B. HSV-1 and risk of Alzheimer's disease. Lancet. 352: 238. PMID 9683242 DOI: 10.1016/S0140-6736(05)77844-2  0.52
1998 Danik M, Poirier J. Apolipoprotein E and neuronal plasticity following experimental de-afferentation and in Alzheimer's disease Biochemical Society Transactions. 26: 262-266. PMID 9649759  0.52
1998 Beffert U, Bertrand P, Champagne D, Gauthier S, Poirier J. HSV-1 in brain and risk of Alzheimer's disease. Lancet. 351: 1330-1. PMID 9643802 DOI: 10.1016/S0140-6736(05)79057-7  0.52
1998 Beffert U, Danik M, Krzywkowski P, Ramassamy C, Berrada F, Poirier J. The neurobiology of apolipoproteins and their receptors in the CNS and Alzheimer's disease. Brain Research. Brain Research Reviews. 27: 119-42. PMID 9622609 DOI: 10.1016/S0165-0173(98)00008-3  0.52
1998 Beffert U, Aumont N, Dea D, Lussier-Cacan S, Davignon J, Poirier J. Beta-amyloid peptides increase the binding and internalization of apolipoprotein E to hippocampal neurons. Journal of Neurochemistry. 70: 1458-66. PMID 9523562  0.52
1998 Farlow MR, Lahiri DK, Poirier J, Davignon J, Schneider L, Hui SL. Treatment outcome of tacrine therapy depends on apolipoprotein genotype and gender of the subjects with Alzheimer's disease. Neurology. 50: 669-77. PMID 9521254  0.52
1998 Thiffault C, Quirion R, Poirier J. Effect of the MAO-B inhibitor, MDL72974, on superoxide dismutase activity and lipid peroxidation levels in the mouse brain. Synapse (New York, N.Y.). 28: 208-11. PMID 9488505 DOI: 10.1002/(SICI)1098-2396(199803)28:3<208::AID-SYN3>3.0.CO;2-E  0.52
1997 Thiffault C, Quirion R, Poirier J. The effect of L-deprenyl, D-deprenyl and MDL72974 on mitochondrial respiration: a possible mechanism leading to an adaptive increase in superoxide dismutase activity. Brain Research. Molecular Brain Research. 49: 127-36. PMID 9387872 DOI: 10.1016/S0169-328X(97)00135-6  0.52
1997 Gauthier S, Panisset M, Nalbantoglu J, Poirier J. Alzheimer's disease: Current knowledge, management and research Cmaj. 157: 1047-1052. PMID 9347775  0.52
1997 Nalbantoglu J, Tirado-Santiago G, Lahsaïni A, Poirier J, Goncalves O, Verge G, Momoli F, Welner SA, Massicotte G, Julien JP, Shapiro ML. Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein. Nature. 387: 500-5. PMID 9168112 DOI: 10.1038/387500a0  0.52
1997 Thiffault C, Lamarre-Théroux L, Quirion R, Poirier J. L-Deprenyl and MDL72974 do not improve the recovery of dopaminergic cells following systemic administration of MPTP in mouse. Brain Research. Molecular Brain Research. 44: 238-44. PMID 9073165 DOI: 10.1016/S0169-328X(96)00203-3  0.52
1996 Farlow MR, Lahiri DK, Poirier J, Davignon J, Hui S. Apolipoprotein E genotype and gender influence response to tacrine therapy. Annals of the New York Academy of Sciences. 802: 101-10. PMID 8993489 DOI: 10.1111/j.1749-6632.1996.tb32603.x  0.52
1996 Gauthier S, Montplaisir J, Petit D, Joanette Y, Feldman H, Mohr E, Nair NP, Poirier J. Outcome variables in presymptomatic individuals at higher risk of developing Alzheimer disease. Alzheimer Disease and Associated Disorders. 10: 19-21. PMID 8876784  0.52
1996 Poirier J. Apolipoprotein E in the brain and its role in alzheimer's disease Journal of Psychiatry and Neuroscience. 21: 128-134. PMID 8820179  0.52
1996 Guillaume D, Bertrand P, Dea D, Davignon J, Poirier J. Apolipoprotein E and low-density lipoprotein binding and internalization in primary cultures of rat astrocytes: Isoform-specific alterations Journal of Neurochemistry. 66: 2410-2418. PMID 8632164  0.52
1996 Beffert U, Poirier J. Apolipoprotein E, plaques, tangles and cholinergic dysfunction in Alzheimer's disease. Annals of the New York Academy of Sciences. 777: 166-74. PMID 8624080  0.52
1995 Poirier J, Beffert U, Dea D, Alonso R, O'Donnell D, Boksa P. Increased levels of statin, a marker of cell cycle arrest, in response to hippocampal neuronal injury. Brain Research. Molecular Brain Research. 34: 57-64. PMID 8750861 DOI: 10.1016/0169-328X(95)00134-E  0.52
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