Julian Knight - Publications

University of Oxford, Oxford, United Kingdom 
HLA, Genetics of inflammation

61 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Berlanga-Taylor AJ, Plant K, Dahl A, Lau E, Hill M, Sims D, Heger A, Emberson J, Armitage J, Clarke R, Knight JC. Genomic Response to Vitamin D Supplementation in the Setting of a Randomized, Placebo-Controlled Trial. Ebiomedicine. PMID 29685792 DOI: 10.1016/j.ebiom.2018.04.010  0.4
2018 Gilchrist JJ, Rautanen A, Fairfax BP, Mills TC, Naranbhai V, Trochet H, Pirinen M, Muthumbi E, Mwarumba S, Njuguna P, Mturi N, Msefula CL, Gondwe EN, MacLennan JM, Chapman SJ, ... ... Knight JC, et al. Risk of nontyphoidal Salmonella bacteraemia in African children is modified by STAT4. Nature Communications. 9: 1014. PMID 29523850 DOI: 10.1038/s41467-017-02398-z  0.52
2018 Lee W, Plant K, Humburg P, Knight JC. AltHapAlignR: improved accuracy of RNA-seq analyses through the use of alternative haplotypes. Bioinformatics (Oxford, England). PMID 29514179 DOI: 10.1093/bioinformatics/bty125  0.4
2017 Kasela S, Kisand K, Tserel L, Kaleviste E, Remm A, Fischer K, Esko T, Westra HJ, Fairfax BP, Makino S, Knight JC, Franke L, Metspalu A, Peterson P, Milani L. Pathogenic implications for autoimmune mechanisms derived by comparative eQTL analysis of CD4+ versus CD8+ T cells. Plos Genetics. 13: e1006643. PMID 28248954 DOI: 10.1371/journal.pgen.1006643  0.52
2017 Kumar D, Puan KJ, Andiappan AK, Lee B, Westerlaken GH, Haase D, Melchiotti R, Li Z, Yusof N, Lum J, Koh G, Foo S, Yeong J, Alves AC, Pekkanen J, ... ... Knight JC, et al. A functional SNP associated with atopic dermatitis controls cell type-specific methylation of the VSTM1 gene locus. Genome Medicine. 9: 18. PMID 28219444 DOI: 10.1186/s13073-017-0404-6  0.52
2016 Burnham KL, Davenport EE, Radhakrishnan J, Humburg P, Gordon AC, Hutton P, Svoren-Jabalera E, Garrard C, Hill AV, Hinds CJ, Knight JC. Shared and Distinct Aspects of the Sepsis Transcriptomic Response to Fecal Peritonitis and Pneumonia. American Journal of Respiratory and Critical Care Medicine. PMID 28036233 DOI: 10.1164/rccm.201608-1685OC  0.4
2016 Vince N, Li H, Ramsuran V, Naranbhai V, Duh FM, Fairfax BP, Saleh B, Knight JC, Anderson SK, Carrington M. HLA-C Level Is Regulated by a Polymorphic Oct1 Binding Site in the HLA-C Promoter Region. American Journal of Human Genetics. PMID 27817866 DOI: 10.1016/j.ajhg.2016.09.023  0.52
2016 Davenport EE, Burnham KL, Radhakrishnan J, Humburg P, Hutton P, Mills TC, Rautanen A, Gordon AC, Garrard C, Hill AV, Hinds CJ, Knight JC. Genomic landscape of the individual host response and outcomes in sepsis: a prospective cohort study. The Lancet. Respiratory Medicine. PMID 26917434 DOI: 10.1016/S2213-2600(16)00046-1  0.52
2015 Naranbhai V, Fletcher HA, Tanner R, O'Shea MK, McShane H, Fairfax BP, Knight JC, Hill AVS. Distinct Transcriptional and Anti-Mycobacterial Profiles of Peripheral Blood Monocytes Dependent on the Ratio of Monocytes: Lymphocytes. Ebiomedicine. 2: 1619-1626. PMID 28958495 DOI: 10.1016/j.ebiom.2015.09.027  0.52
2015 Naranbhai V, Fletcher HA, Tanner R, O'Shea MK, McShane H, Fairfax BP, Knight JC, Hill AV. Distinct Transcriptional and Anti-Mycobacterial Profiles of Peripheral Blood Monocytes Dependent on the Ratio of Monocytes: Lymphocytes. Ebiomedicine. 2: 1619-1626. PMID 26870787 DOI: 10.1016/j.ebiom.2015.09.027  0.52
2015 Bentham J, Morris DL, Cunninghame Graham DS, Pinder CL, Tombleson P, Behrens TW, Martín J, Fairfax BP, Knight JC, Chen L, Replogle J, Syvänen AC, Rönnblom L, Graham RR, Wither JE, et al. Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus. Nature Genetics. PMID 26502338 DOI: 10.1038/ng.3434  0.52
2015 Vecellio M, Roberts AR, Cohen CJ, Cortes A, Knight JC, Bowness P, Wordsworth BP. The genetic association of RUNX3 with ankylosing spondylitis can be explained by allele-specific effects on IRF4 recruitment that alter gene expression. Annals of the Rheumatic Diseases. PMID 26452539 DOI: 10.1136/annrheumdis-2015-207490  0.52
2015 Gilchrist JJ, Mills TC, Naranbhai V, Chapman SJ, Fairfax BP, Knight JC, Williams TN, Scott JA, MacLennan CA, Rautanen A, Hill AV. Genetic variants associated with non-typhoidal Salmonella bacteraemia in African children. Lancet (London, England). 385: S13. PMID 26312835 DOI: 10.1016/S0140-6736(15)60328-2  0.52
2015 Naranbhai V, Fairfax BP, Makino S, Humburg P, Wong D, Ng E, Hill AV, Knight JC. Genomic modulators of gene expression in human neutrophils. Nature Communications. 6: 7545. PMID 26151758 DOI: 10.1038/ncomms8545  0.52
2015 van Schouwenburg PA, Davenport EE, Kienzler AK, Marwah I, Wright B, Lucas M, Malinauskas T, Martin HC, Lockstone HE, Cazier JB, Chapel HM, Knight JC, Patel SY. Application of whole genome and RNA sequencing to investigate the genomic landscape of common variable immunodeficiency. Clinical Immunology (Orlando, Fla.). PMID 26122175 DOI: 10.1016/j.clim.2015.05.020  0.52
2015 Taylor JC, Martin HC, Lise S, Broxholme J, Cazier JB, Rimmer A, Kanapin A, Lunter G, Fiddy S, Allan C, Aricescu AR, Attar M, Babbs C, Becq J, Beeson D, ... ... Knight JC, et al. Factors influencing success of clinical genome sequencing across a broad spectrum of disorders. Nature Genetics. 47: 717-26. PMID 25985138 DOI: 10.1038/ng.3304  0.52
2015 Westra HJ, Arends D, Esko T, Peters MJ, Schurmann C, Schramm K, Kettunen J, Yaghootkar H, Fairfax BP, Andiappan AK, Li Y, Fu J, Karjalainen J, Platteel M, Visschedijk M, ... ... Knight JC, et al. Cell Specific eQTL Analysis without Sorting Cells. Plos Genetics. 11: e1005223. PMID 25955312 DOI: 10.1371/journal.pgen.1005223  0.52
2015 Edwards AM, Arrowsmith CH, Bountra C, Bunnage ME, Feldmann M, Knight JC, Patel DD, Prinos P, Taylor MD, Sundström M. Preclinical target validation using patient-derived cells. Nature Reviews. Drug Discovery. 14: 149-50. PMID 25722227 DOI: 10.1038/nrd4565  0.52
2015 Simpson NH, Ceroni F, Reader RH, Covill LE, Knight JC, Hennessy ER, Bolton PF, Conti-Ramsden G, O'Hare A, Baird G, Fisher SE, Newbury DF. Genome-wide analysis identifies a role for common copy number variants in specific language impairment. European Journal of Human Genetics : Ejhg. PMID 25585696 DOI: 10.1038/ejhg.2014.296  0.52
2015 Rautanen A, Mills TC, Gordon AC, Hutton P, Steffens M, Nuamah R, Chiche JD, Parks T, Chapman SJ, Davenport EE, Elliott KS, Bion J, Lichtner P, Meitinger T, Wienker TF, ... ... Knight JC, et al. Genome-wide association study of survival from sepsis due to pneumonia: an observational cohort study. The Lancet. Respiratory Medicine. 3: 53-60. PMID 25533491 DOI: 10.1016/S2213-2600(14)70290-5  0.52
2015 Davenport EE, Antrobus RD, Lillie PJ, Gilbert S, Knight JC. Transcriptomic profiling facilitates classification of response to influenza challenge. Journal of Molecular Medicine (Berlin, Germany). 93: 105-14. PMID 25345603 DOI: 10.1007/s00109-014-1212-8  0.52
2014 Knight JC. Approaches for establishing the function of regulatory genetic variants involved in disease. Genome Medicine. 6: 92. PMID 25473428 DOI: 10.1186/s13073-014-0092-4  0.52
2014 Wong D, Lee W, Humburg P, Makino S, Lau E, Naranbhai V, Fairfax BP, Chan K, Plant K, Knight JC. Genomic mapping of the MHC transactivator CIITA using an integrated ChIP-seq and genetical genomics approach. Genome Biology. 15: 494. PMID 25366989 DOI: 10.1186/s13059-014-0494-z  0.52
2014 Fairfax BP, Knight JC. Genetics of gene expression in immunity to infection. Current Opinion in Immunology. 30: 63-71. PMID 25078545 DOI: 10.1016/j.coi.2014.07.001  0.52
2014 Fairfax BP, Humburg P, Makino S, Naranbhai V, Wong D, Lau E, Jostins L, Plant K, Andrews R, McGee C, Knight JC. Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression. Science (New York, N.Y.). 343: 1246949. PMID 24604202 DOI: 10.1126/science.1246949  0.52
2014 Berlanga-Taylor AJ, Knight JC. An integrated approach to defining genetic and environmental determinants for major clinical outcomes involving vitamin D. Molecular Diagnosis & Therapy. 18: 261-72. PMID 24557774 DOI: 10.1007/s40291-014-0087-2  0.52
2014 Nudel R, Simpson NH, Baird G, O'Hare A, Conti-Ramsden G, Bolton PF, Hennessy ER, Monaco AP, Knight JC, Winney B, Fisher SE, Newbury DF. Associations of HLA alleles with specific language impairment. Journal of Neurodevelopmental Disorders. 6: 1. PMID 24433325 DOI: 10.1186/1866-1955-6-1  0.52
2014 Plant K, Fairfax BP, Makino S, Vandiedonck C, Radhakrishnan J, Knight JC. Fine mapping genetic determinants of the highly variably expressed MHC gene ZFP57. European Journal of Human Genetics : Ejhg. 22: 568-71. PMID 24193346 DOI: 10.1038/ejhg.2013.244  0.52
2014 Simpson NH, Addis L, Brandler WM, Slonims V, Clark A, Watson J, Scerri TS, Hennessy ER, Bolton PF, Conti-Ramsden G, Fairfax BP, Knight JC, Stein J, Talcott JB, O'Hare A, et al. Increased prevalence of sex chromosome aneuploidies in specific language impairment and dyslexia. Developmental Medicine and Child Neurology. 56: 346-53. PMID 24117048 DOI: 10.1111/dmcn.12294  0.52
2013 Westra HJ, Peters MJ, Esko T, Yaghootkar H, Schurmann C, Kettunen J, Christiansen MW, Fairfax BP, Schramm K, Powell JE, Zhernakova A, Zhernakova DV, Veldink JH, Van den Berg LH, Karjalainen J, ... ... Knight JC, et al. Systematic identification of trans eQTLs as putative drivers of known disease associations. Nature Genetics. 45: 1238-43. PMID 24013639 DOI: 10.1038/ng.2756  0.52
2013 Trowsdale J, Knight JC. Major histocompatibility complex genomics and human disease. Annual Review of Genomics and Human Genetics. 14: 301-23. PMID 23875801 DOI: 10.1146/annurev-genom-091212-153455  0.52
2013 Knight JC. Genomic modulators of the immune response. Trends in Genetics : Tig. 29: 74-83. PMID 23122694 DOI: 10.1016/j.tig.2012.10.006  0.52
2012 Simpson PD, Moysi E, Wicks K, Sudan K, Rowland-Jones SL, McMichael AJ, Knight J, Gillespie GM. Functional differences exist between TNFα promoters encoding the common -237G SNP and the rarer HLA-B*5701-linked A variant. Plos One. 7: e40100. PMID 22808100 DOI: 10.1371/journal.pone.0040100  0.52
2012 Fairfax BP, Makino S, Radhakrishnan J, Plant K, Leslie S, Dilthey A, Ellis P, Langford C, Vannberg FO, Knight JC. Genetics of gene expression in primary immune cells identifies cell type-specific master regulators and roles of HLA alleles. Nature Genetics. 44: 502-10. PMID 22446964 DOI: 10.1038/ng.2205  0.52
2011 Vandiedonck C, Taylor MS, Lockstone HE, Plant K, Taylor JM, Durrant C, Broxholme J, Fairfax BP, Knight JC. Pervasive haplotypic variation in the spliceo-transcriptome of the human major histocompatibility complex. Genome Research. 21: 1042-54. PMID 21628452 DOI: 10.1101/gr.116681.110  0.52
2011 Holt RJ, Zhang Y, Binia A, Dixon AL, Vandiedonck C, Cookson WO, Knight JC, Moffatt MF. Allele-specific transcription of the asthma-associated PHD finger protein 11 gene (PHF11) modulated by octamer-binding transcription factor 1 (Oct-1). The Journal of Allergy and Clinical Immunology. 127: 1054-62.e1-2. PMID 21320718 DOI: 10.1016/j.jaci.2010.12.015  0.52
2011 Fairfax BP, Davenport EE, Makino S, Hill AV, Vannberg FO, Knight JC. A common haplotype of the TNF receptor 2 gene modulates endotoxin tolerance. Journal of Immunology (Baltimore, Md. : 1950). 186: 3058-65. PMID 21282507 DOI: 10.4049/jimmunol.1001791  0.52
2011 Andraos C, Koorsen G, Knight JC, Bornman L. Vitamin D receptor gene methylation is associated with ethnicity, tuberculosis, and TaqI polymorphism. Human Immunology. 72: 262-8. PMID 21168462 DOI: 10.1016/j.humimm.2010.12.010  0.52
2010 Paracchini S, Monaco AP, Knight JC. An allele-specific gene expression assay to test the functional basis of genetic associations. Journal of Visualized Experiments : Jove. PMID 21085102 DOI: 10.3791/2279  0.52
2010 Maugeri N, Radhakrishnan J, Knight JC. Genetic determinants of HSP70 gene expression following heat shock. Human Molecular Genetics. 19: 4939-47. PMID 20876613 DOI: 10.1093/hmg/ddq418  0.52
2010 Ramagopalan SV, Heger A, Berlanga AJ, Maugeri NJ, Lincoln MR, Burrell A, Handunnetthi L, Handel AE, Disanto G, Orton SM, Watson CT, Morahan JM, Giovannoni G, Ponting CP, Ebers GC, ... Knight JC, et al. A ChIP-seq defined genome-wide map of vitamin D receptor binding: associations with disease and evolution. Genome Research. 20: 1352-60. PMID 20736230 DOI: 10.1101/gr.107920.110  0.52
2010 Knight JC. Understanding human genetic variation in the era of high-throughput sequencing. Embo Reports. 11: 650-2. PMID 20725090 DOI: 10.1038/embor.2010.126  0.52
2010 Wong SH, Gochhait S, Malhotra D, Pettersson FH, Teo YY, Khor CC, Rautanen A, Chapman SJ, Mills TC, Srivastava A, Rudko A, Freidin MB, Puzyrev VP, Ali S, Aggarwal S, ... ... Knight JC, et al. Leprosy and the adaptation of human toll-like receptor 1. Plos Pathogens. 6: e1000979. PMID 20617178 DOI: 10.1371/journal.ppat.1000979  0.52
2010 Fairfax BP, Vannberg FO, Radhakrishnan J, Hakonarson H, Keating BJ, Hill AV, Knight JC. An integrated expression phenotype mapping approach defines common variants in LEP, ALOX15 and CAPNS1 associated with induction of IL-6. Human Molecular Genetics. 19: 720-30. PMID 19942621 DOI: 10.1093/hmg/ddp530  0.52
2009 Knight JC. Insights into the nature and consequences of our variable genome. Briefings in Functional Genomics & Proteomics. 8: 343-4. PMID 19808931 DOI: 10.1093/bfgp/elp039  0.52
2009 Vandiedonck C, Knight JC. The human Major Histocompatibility Complex as a paradigm in genomics research. Briefings in Functional Genomics & Proteomics. 8: 379-94. PMID 19468039 DOI: 10.1093/bfgp/elp010  0.52
2009 Gasperíková D, Tribble ND, Staník J, Hucková M, Misovicová N, van de Bunt M, Valentínová L, Barrow BA, Barák L, Dobránsky R, Bereczková E, Michálek J, Wicks K, Colclough K, Knight JC, et al. Identification of a novel beta-cell glucokinase (GCK) promoter mutation (-71G>C) that modulates GCK gene expression through loss of allele-specific Sp1 binding causing mild fasting hyperglycemia in humans. Diabetes. 58: 1929-35. PMID 19411616 DOI: 10.2337/db09-0070  0.52
2009 Ramagopalan SV, Knight JC, Ebers GC. Multiple sclerosis and the major histocompatibility complex. Current Opinion in Neurology. 22: 219-25. PMID 19387341 DOI: 10.1097/WCO.0b013e32832b5417  0.52
2009 Dennis MY, Paracchini S, Scerri TS, Prokunina-Olsson L, Knight JC, Wade-Martins R, Coggill P, Beck S, Green ED, Monaco AP. A common variant associated with dyslexia reduces expression of the KIAA0319 gene. Plos Genetics. 5: e1000436. PMID 19325871 DOI: 10.1371/journal.pgen.1000436  0.52
2009 Ramagopalan SV, Maugeri NJ, Handunnetthi L, Lincoln MR, Orton SM, Dyment DA, Deluca GC, Herrera BM, Chao MJ, Sadovnick AD, Ebers GC, Knight JC. Expression of the multiple sclerosis-associated MHC class II Allele HLA-DRB1*1501 is regulated by vitamin D. Plos Genetics. 5: e1000369. PMID 19197344 DOI: 10.1371/journal.pgen.1000369  0.52
2008 Chao MJ, Barnardo MC, Lincoln MR, Ramagopalan SV, Herrera BM, Dyment DA, Montpetit A, Sadovnick AD, Knight JC, Ebers GC. HLA class I alleles tag HLA-DRB1*1501 haplotypes for differential risk in multiple sclerosis susceptibility. Proceedings of the National Academy of Sciences of the United States of America. 105: 13069-74. PMID 18765817 DOI: 10.1073/pnas.0801042105  0.52
2008 Taylor JM, Wicks K, Vandiedonck C, Knight JC. Chromatin profiling across the human tumour necrosis factor gene locus reveals a complex, cell type-specific landscape with novel regulatory elements. Nucleic Acids Research. 36: 4845-62. PMID 18653526 DOI: 10.1093/nar/gkn444  0.52
2008 Gordon A, Knight JC, Hinds CJ. Genes and sepsis: how tight is the fit? Critical Care Medicine. 36: 1652-4. PMID 18448923 DOI: 10.1097/CCM.0b013e318170f358  0.52
2007 Ramagopalan SV, Knight M, Ebers GC, Knight JC. Origins of magic: review of genetic and epigenetic effects. Bmj (Clinical Research Ed.). 335: 1299-301. PMID 18156238 DOI: 10.1136/bmj.39414.582639.BE  0.52
2007 Hull J, Campino S, Rowlands K, Chan MS, Copley RR, Taylor MS, Rockett K, Elvidge G, Keating B, Knight J, Kwiatkowski D. Identification of common genetic variation that modulates alternative splicing. Plos Genetics. 3: e99. PMID 17571926 DOI: 10.1371/journal.pgen.0030099  0.52
2006 Knight JC. Analysis of allele-specific gene expression. Methods in Molecular Biology (Clifton, N.J.). 338: 153-65. PMID 16888357 DOI: 10.1385/1-59745-097-9:153  0.52
2006 Paracchini S, Thomas A, Castro S, Lai C, Paramasivam M, Wang Y, Keating BJ, Taylor JM, Hacking DF, Scerri T, Francks C, Richardson AJ, Wade-Martins R, Stein JF, Knight JC, et al. The chromosome 6p22 haplotype associated with dyslexia reduces the expression of KIAA0319, a novel gene involved in neuronal migration. Human Molecular Genetics. 15: 1659-66. PMID 16600991 DOI: 10.1093/hmg/ddl089  0.52
2005 Knight JC. Regulatory polymorphisms underlying complex disease traits. Journal of Molecular Medicine (Berlin, Germany). 83: 97-109. PMID 15592805 DOI: 10.1007/s00109-004-0603-7  0.52
2004 Knight JC, Keating BJ, Kwiatkowski DP. Allele-specific repression of lymphotoxin-alpha by activated B cell factor-1. Nature Genetics. 36: 394-9. PMID 15052269 DOI: 10.1038/ng1331  0.52
2003 Knight JC, Keating BJ, Rockett KA, Kwiatkowski DP. In vivo characterization of regulatory polymorphisms by allele-specific quantification of RNA polymerase loading. Nature Genetics. 33: 469-75. PMID 12627232 DOI: 10.1038/ng1124  0.52
2003 Knight JC. Functional implications of genetic variation in non-coding DNA for disease susceptibility and gene regulation. Clinical Science (London, England : 1979). 104: 493-501. PMID 12513691 DOI: 10.1042/CS20020304  0.52
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