| Year |
Citation |
Score |
| 2020 |
Xie F, Martin-Acosta P, Li BX, Xiao X. Mechanistic Insights into the Activation of Ester Prodrugs of 666-15. Bioorganic & Medicinal Chemistry Letters. 127455. PMID 32730943 DOI: 10.1016/J.Bmcl.2020.127455 |
0.389 |
|
| 2018 |
Meng Q, Li BX, Xiao X. Toward Developing Chemical Modulators of Hsp60 as Potential Therapeutics. Frontiers in Molecular Biosciences. 5: 35. PMID 29732373 DOI: 10.3389/Fmolb.2018.00035 |
0.302 |
|
| 2018 |
Li BX, Chen J, Chao B, David LL, Xiao X. Anticancer pyrroloquinazoline LBL1 targets nuclear lamins. Acs Chemical Biology. PMID 29648791 DOI: 10.1021/Acschembio.8B00266 |
0.331 |
|
| 2015 |
Xie F, Li BX, Kassenbrock A, Xue C, Wang X, Qian DZ, Sears RC, Xiao X. Identification of a Potent Inhibitor of CREB-Mediated Gene Transcription with Efficacious in Vivo Anticancer Activity. Journal of Medicinal Chemistry. 58: 5075-87. PMID 26023867 DOI: 10.1021/Acs.Jmedchem.5B00468 |
0.397 |
|
| 2015 |
Chao B, Li BX, Xiao X. The chemistry and pharmacology of privileged pyrroloquinazolines. Medchemcomm. 6: 510-520. PMID 25937878 DOI: 10.1039/C4Md00485J |
0.306 |
|
| 2014 |
Li BX, Xie F, Fan Q, Barnhart KM, Moore CE, Rheingold AL, Xiao X. Novel Type of Prodrug Activation through a Long-Range O,N-Acyl Transfer: A Case of Water-Soluble CREB Inhibitor. Acs Medicinal Chemistry Letters. 5: 1104-9. PMID 25313320 DOI: 10.1021/Ml500330N |
0.354 |
|
| 2013 |
Chen J, Kassenbrock A, Li BX, Xiao X. Discovery of a Potent Anti-tumor Agent through Regioselective Mono-N-acylation of 7H-Pyrrolo[3,2-f]quinazoline-1,3-diamine. Medchemcomm. 4: 1275-1282. PMID 24163729 DOI: 10.1039/C3Md00134B |
0.312 |
|
| 2013 |
Xie F, Li BX, Broussard C, Xiao X. Identification, synthesis and evaluation of substituted benzofurazans as inhibitors of CREB-mediated gene transcription. Bioorganic & Medicinal Chemistry Letters. 23: 5371-5. PMID 23953193 DOI: 10.1016/J.Bmcl.2013.07.053 |
0.386 |
|
| 2013 |
Mitton B, Dutta R, Hsu Y, Ochoa R, Landaw E, Xiao X, Sakamoto K. The pp90rsk-CREB Signaling Pathway Regulates Apoptosis In Acute Myelogenous Leukemia Blood. 122: 3801-3801. DOI: 10.1182/Blood.V122.21.3801.3801 |
0.323 |
|
| 2013 |
Xiao X, Li B, Xie F, Fan Q, Xue C, Qian D. Abstract P4-15-08: Discovery of a potent inhibitor of CREB-mediated gene transcription that completely suppresses the growth of triple-negative breast cancer cells Cancer Research. 73. DOI: 10.1158/0008-5472.Sabcs13-P4-15-08 |
0.391 |
|
| 2012 |
Li BX, Yamanaka K, Xiao X. Structure-activity relationship studies of naphthol AS-E and its derivatives as anticancer agents by inhibiting CREB-mediated gene transcription. Bioorganic & Medicinal Chemistry. 20: 6811-20. PMID 23102993 DOI: 10.1016/J.Bmc.2012.09.056 |
0.372 |
|
| 2012 |
Jiang M, Li BX, Xie F, Delaney F, Xiao X. Design, synthesis, and biological evaluation of conformationally constrained analogues of naphthol AS-E as inhibitors of CREB-mediated gene transcription. Journal of Medicinal Chemistry. 55: 4020-4. PMID 22458559 DOI: 10.1021/Jm300043C |
0.385 |
|
| 2011 |
Aldana-Masangkay GI, Mitton B, Ikeda AK, Yamada K, Li B, Fan Q, Landaw E, Xiao X, Sakamoto KM. A Small Molecule Inhibitor Targeting CREB and CBP Inhibits Proliferation of AML Cells In Vitro and In Vivo, Blood. 118: 3607-3607. DOI: 10.1182/Blood.V118.21.3607.3607 |
0.333 |
|
| 2010 |
Xiao X, Li BX, Mitton B, Ikeda A, Sakamoto KM. Targeting CREB for cancer therapy: friend or foe. Current Cancer Drug Targets. 10: 384-91. PMID 20370681 DOI: 10.2174/156800910791208535 |
0.357 |
|
| 2010 |
Mitton B, Ikeda A, Yamada K, Li B, Fan Q, Landaw E, Xiao X, Sakamoto KM. Inhibitor of the CREB Proto-Oncogene Suppresses AML Cell Proliferation and Induces Apoptosis In Vitro and In Vivo Blood. 116: 3270-3270. DOI: 10.1182/Blood.V116.21.3270.3270 |
0.316 |
|
| 2007 |
Xiao X, Yu P, Lim HS, Sikder D, Kodadek T. Design and synthesis of a cell-permeable synthetic transcription factor mimic Journal of Combinatorial Chemistry. 9: 592-600. PMID 17530904 DOI: 10.1021/Cc070023A |
0.38 |
|
| 2006 |
Alluri P, Liu B, Yu P, Xiao X, Kodadek T. Isolation and characterization of coactivator-binding peptoids from a combinatorial library Molecular Biosystems. 2: 568-579. PMID 17216038 DOI: 10.1039/B608924K |
0.344 |
|
| 2006 |
Xiao X, Antony S, Pommier Y, Cushman M. Total synthesis and biological evaluation of 22-hydroxyacuminatine Journal of Medicinal Chemistry. 49: 1408-1412. PMID 16480276 DOI: 10.1021/Jm051116E |
0.314 |
|
| 2005 |
Xiao X, Miao ZH, Antony S, Pommier Y, Cushman M. Dihydroindenoisoquinolines function as prodrugs of indenoisoquinolines Bioorganic and Medicinal Chemistry Letters. 15: 2795-2798. PMID 15911256 DOI: 10.1016/J.Bmcl.2005.03.101 |
0.34 |
|
| 2004 |
Xiao X, Antony S, Kohlhagen G, Pommier Y, Cushman M. Novel autoxidative cleavage reaction of 9-fluoredenes discovered during synthesis of a potential DNA-threading indenoisoquinoline Journal of Organic Chemistry. 69: 7495-7501. PMID 15497974 DOI: 10.1021/Jo048808F |
0.349 |
|
| 2004 |
Xiao X, Antony S, Kohlhagen G, Pommier Y, Cushman M. Design, synthesis, and biological evaluation of cytotoxic 11-aminoalkenylindenoisoquinoline and 11-diaminoalkenylindenoisoquinoline topoisomerase I inhibitors Bioorganic and Medicinal Chemistry. 12: 5147-5160. PMID 15351398 DOI: 10.1016/J.Bmc.2004.07.027 |
0.353 |
|
| 2003 |
Nagarajan M, Xiao X, Antony S, Kohlhagen G, Pommier Y, Cushman M. Design, Synthesis, and Biological Evaluation of Indenoisoquinoline Topoisomerase I Inhibitors Featuring Polyamine Side Chains on the Lactam Nitrogen Journal of Medicinal Chemistry. 46: 5712-5724. PMID 14667224 DOI: 10.1021/Jm030313F |
0.381 |
|
| 2003 |
Fox BM, Xiao X, Antony S, Kohlhagen G, Pommier Y, Staker BL, Stewart L, Cushman M. Design, synthesis, and biological evaluation of cytotoxic 11-alkenylindenoisoquinoline topoisomerase I inhibitors and indenoisoquinoline-camptothecin hybrids. Journal of Medicinal Chemistry. 46: 3275-82. PMID 12852757 DOI: 10.1021/Jm0300476 |
0.38 |
|
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