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Nadine S. Jahchan, Ph.D. - Publications

Affiliations: 
2010 Molecular & Cell Biology University of California, Berkeley, Berkeley, CA, United States 
Area:
Signal transduction pathways mediated by receptors and the mechanisms controlling the activity of the receptor kinases
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29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Juric V, Mayes E, Binnewies M, Lee T, Canaday P, Pollack JL, Rudolph J, Du X, Liu VM, Dash S, Palmer R, Jahchan NS, Ramoth ÅJ, Lacayo S, Mankikar S, et al. TREM1 activation of myeloid cells promotes antitumor immunity. Science Translational Medicine. 15: eadd9990. PMID 37647386 DOI: 10.1126/scitranslmed.add9990  0.344
2021 Binnewies M, Pollack JL, Rudolph J, Dash S, Abushawish M, Lee T, Jahchan NS, Canaday P, Lu E, Norng M, Mankikar S, Liu VM, Du X, Chen A, Mehta R, et al. Targeting TREM2 on tumor-associated macrophages enhances immunotherapy. Cell Reports. 37: 109844. PMID 34686340 DOI: 10.1016/j.celrep.2021.109844  0.309
2020 Riess JW, Jahchan NS, Das M, Zach Koontz M, Kunz PL, Wakelee HA, Schatzberg A, Sage J, Neal JW. A PHASE IIA STUDY REPOSITIONING DESIPRAMINE IN SMALL CELL LUNG CANCER AND OTHER HIGH-GRADE NEUROENDOCRINE TUMORS. Cancer Treatment and Research Communications. 23: 100174. PMID 32413603 DOI: 10.1016/J.Ctarc.2020.100174  0.428
2019 Yang D, Qu F, Cai H, Chuang CH, Lim JS, Jahchan N, Grüner BM, S Kuo C, Kong C, Oudin MJ, Winslow MM, Sage J. Axon-like protrusions promote small cell lung cancer migration and metastasis. Elife. 8. PMID 31833833 DOI: 10.7554/Elife.50616  0.376
2019 Jahchan NS, Mujal AM, Pollack JL, Binnewies M, Sriram V, Reyno L, Krummel MF. Tuning the Tumor Myeloid Microenvironment to Fight Cancer. Frontiers in Immunology. 10: 1611. PMID 31402908 DOI: 10.3389/Fimmu.2019.01611  0.415
2019 Yang D, Qu F, Cai H, Chuang C, Lim JS, Jahchan N, Grüner BM, Kuo CS, Kong C, Oudin MJ, Winslow MM, Sage J. Author response: Axon-like protrusions promote small cell lung cancer migration and metastasis Elife. DOI: 10.7554/Elife.50616.Sa2  0.344
2019 Binnewies M, Abushawish M, Lee T, Le T, Pollack JL, Lu E, Chen A, Mehta R, Jahchan N, Huang V, Du X, Dash S, Norng M, Pal A, Baker KP, et al. Abstract C104: Therapeutic targeting of TREM2+ tumor-associated macrophages as a means of overcoming checkpoint inhibitor resistance Molecular Cancer Therapeutics. 18. DOI: 10.1158/1535-7163.Targ-19-C104  0.425
2018 Yang D, Denny SK, Greenside PG, Chaikovsky AC, Brady JJ, Ouadah Y, Granja JM, Jahchan NS, Lim JS, Kwok S, Kong CS, Berghoff AS, Schmitt A, Reinhardt HC, Park KS, et al. Intertumoral Heterogeneity in SCLC Is Influenced by the Cell Type of Origin. Cancer Discovery. PMID 30228179 DOI: 10.1158/2159-8290.Cd-17-0987  0.431
2018 Rew Y, Du X, Eksterowicz J, Zhou H, Jahchan N, Zhu L, Yan X, Kawai H, McGee LR, Medina JC, Huang T, Chen C, Zavorotinskaya T, Sutimantanapi D, Waszczuk J, et al. Discovery of a Potent and Selective Steroidal Glucocorticoid Receptor Antagonist (ORIC-101). Journal of Medicinal Chemistry. PMID 30091920 DOI: 10.1021/Acs.Jmedchem.8B00743  0.339
2018 Sunshine JC, Jahchan NS, Sage J, Choi J. Are there multiple cells of origin of Merkel cell carcinoma? Oncogene. PMID 29321666 DOI: 10.1038/S41388-017-0073-3  0.39
2018 Jahchan N, Zhou H, Kong W, Weeney DM, Tracy T, Stice J, Sutimantanapi D, Chen C, Huang T, Rew Y, Du X, Zavorotinskaya T, Sun D, Ye Q, Jackson E, et al. Abstract 1968: A novel glucocorticoid receptor (GR) antagonist overcomes GR-mediated chemoresistance in triple-negative breast cancer Cancer Research. 78: 1968-1968. DOI: 10.1158/1538-7445.Am2018-1968  0.402
2018 Jahchan N, Zhou H, Stice J, Kong W, McWeeney D, Sun D, Rew Y, Du X, Zhu L, Ye Q, Jackson EL, Fantin V. Abstract A133: Development of murine models to evaluate the impact of glucocorticoid receptor (GR) inhibition on chemotherapy response Molecular Cancer Therapeutics. 17. DOI: 10.1158/1535-7163.Targ-17-A133  0.423
2017 Lim JS, Ibaseta A, Fischer MM, Cancilla B, O'Young G, Cristea S, Luca VC, Yang D, Jahchan NS, Hamard C, Antoine M, Wislez M, Kong C, Cain J, Liu YW, et al. Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer. Nature. PMID 28489825 DOI: 10.1038/Nature22323  0.463
2016 Jahchan NS, Lim JS, Bola B, Morris K, Seitz G, Tran KQ, Xu L, Trapani F, Morrow CJ, Cristea S, Coles GL, Yang D, Vaka D, Kareta MS, George J, et al. Identification and Targeting of Long-Term Tumor-Propagating Cells in Small Cell Lung Cancer. Cell Reports. PMID 27373157 DOI: 10.1016/J.Celrep.2016.06.021  0.449
2016 Weiskopf K, Jahchan NS, Schnorr PJ, Cristea S, Ring AM, Maute RL, Volkmer AK, Volkmer JP, Liu J, Lim JS, Yang D, Seitz G, Nguyen T, Wu D, Jude K, et al. CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer. The Journal of Clinical Investigation. PMID 27294525 DOI: 10.1172/Jci81603  0.35
2016 Zhu Q, Le Scolan E, Jahchan N, Ji X, Xu A, Luo K. SnoN Antagonizes the Hippo Kinase Complex to Promote TAZ Signaling during Breast Carcinogenesis. Developmental Cell. PMID 27237790 DOI: 10.1016/J.Devcel.2016.05.002  0.594
2016 Krampitz GW, George BM, Willingham SB, Volkmer JP, Weiskopf K, Jahchan N, Newman AM, Sahoo D, Zemek AJ, Yanovsky RL, Nguyen JK, Schnorr PJ, Mazur PK, Sage J, Longacre TA, et al. Identification of tumorigenic cells and therapeutic targets in pancreatic neuroendocrine tumors. Proceedings of the National Academy of Sciences of the United States of America. PMID 27035983 DOI: 10.1073/Pnas.1600007113  0.461
2016 Lim JS, Ibaseta A, Yang D, Jahchan NS, Sage J. Abstract A37: Tumor heterogeneity in SCLC: A role for endogenous Notch signaling Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Devbiolca15-A37  0.511
2015 George J, Lim JS, Jang SJ, Cun Y, Ozretić L, Kong G, Leenders F, Lu X, Fernández-Cuesta L, Bosco G, Müller C, Dahmen I, Jahchan NS, Park KS, Yang D, et al. Comprehensive genomic profiles of small cell lung cancer. Nature. 524: 47-53. PMID 26168399 DOI: 10.1038/Nature14664  0.391
2015 Xu L, Hazard FK, Zmoos AF, Jahchan N, Chaib H, Garfin PM, Rangaswami A, Snyder MP, Sage J. Genomic analysis of fibrolamellar hepatocellular carcinoma. Human Molecular Genetics. 24: 50-63. PMID 25122662 DOI: 10.1093/Hmg/Ddu418  0.374
2014 Jahchan NS, Dudley JT, Mazur PK, Flores N, Yang D, Palmerton A, Zmoos A, Vaka D, Tran KQt, Zhou M, Krasinska K, Riess JW, Neal JW, Khatri P, Park KS, et al. Abstract 4610: A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors Cancer Research. 74: 4610-4610. DOI: 10.1158/1538-7445.Am2014-4610  0.459
2014 Weiskopf K, Schnorr PJ, Jahchan N, Ring AM, Maute RL, Volkmer AK, Volkmer J, Garcia KC, Sage J, Weissman IL. Abstract 3629: Overcoming macrophage immunosuppression in small cell lung cancer with high-affinity SIRPa variants Cancer Research. 74: 3629-3629. DOI: 10.1158/1538-7445.Am2014-3629  0.388
2013 Jahchan NS, Dudley JT, Mazur PK, Flores N, Yang D, Palmerton A, Zmoos AF, Vaka D, Tran KQ, Zhou M, Krasinska K, Riess JW, Neal JW, Khatri P, Park KS, et al. A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors. Cancer Discovery. 3: 1364-77. PMID 24078773 DOI: 10.1158/2159-8290.Cd-13-0183  0.445
2013 Jahchan NS, Ouyang G, Luo K. Expression profiles of SnoN in normal and cancerous human tissues support its tumor suppressor role in human cancer. Plos One. 8: e55794. PMID 23418461 DOI: 10.1371/Journal.Pone.0055794  0.617
2012 Jahchan NS, Wang D, Bissell MJ, Luo K. SnoN regulates mammary gland alveologenesis and onset of lactation by promoting prolactin/Stat5 signaling. Development (Cambridge, England). 139: 3147-56. PMID 22833129 DOI: 10.1242/Dev.079616  0.57
2010 Jahchan NS, Luo K. SnoN in mammalian development, function and diseases. Current Opinion in Pharmacology. 10: 670-5. PMID 20822955 DOI: 10.1016/J.Coph.2010.08.006  0.585
2010 Jahchan NS, You YH, Muller WJ, Luo K. Transforming growth factor-beta regulator SnoN modulates mammary gland branching morphogenesis, postlactational involution, and mammary tumorigenesis. Cancer Research. 70: 4204-13. PMID 20460516 DOI: 10.1158/0008-5472.Can-10-0135  0.577
2008 He N, Jahchan NS, Hong E, Li Q, Bayfield MA, Maraia RJ, Luo K, Zhou Q. A La-related protein modulates 7SK snRNP integrity to suppress P-TEFb-dependent transcriptional elongation and tumorigenesis. Molecular Cell. 29: 588-99. PMID 18249148 DOI: 10.1016/J.Molcel.2008.01.003  0.537
2006 Zegzouti H, Anthony RG, Jahchan N, Bögre L, Christensen SK. Phosphorylation and activation of PINOID by the phospholipid signaling kinase 3-phosphoinositide-dependent protein kinase 1 (PDK1) in Arabidopsis Proceedings of the National Academy of Sciences of the United States of America. 103: 6404-6409. PMID 16601102 DOI: 10.1073/Pnas.0510283103  0.319
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