| Year |
Citation |
Score |
| 2023 |
Smith ED, Vo Q, Giasson BI, Borchelt DR, Prokop S, Chakrabarty P. Human tauopathy strains defined by phosphorylation in R1-R2 repeat domains of tau. Acta Neuropathologica Communications. 11: 172. PMID 37891635 DOI: 10.1186/s40478-023-01664-0 |
0.335 |
|
| 2023 |
Williams T, Bathe T, Vo Q, Sacilotto P, McFarland K, Ruiz AJ, Hery GP, Sullivan P, Borchelt DR, Prokop S, Chakrabarty P. Humanized APOE genotypes influence lifespan independently of tau aggregation in the P301S mouse model of tauopathy. Acta Neuropathologica Communications. 11: 99. PMID 37337279 DOI: 10.1186/s40478-023-01581-2 |
0.443 |
|
| 2022 |
Ibanez KR, McFarland KN, Phillips J, Allen M, Lessard CB, Zobel L, De La Cruz EG, Shah S, Vo Q, Wang X, Quicksall Z, Ryu D, Funk C, Ertekin-Taner N, Prokop S, ... ... Chakrabarty P, et al. Deletion of Abi3/Gngt2 influences age-progressive amyloid β and tau pathologies in distinctive ways. Alzheimer's Research & Therapy. 14: 104. PMID 35897046 DOI: 10.1186/s13195-022-01044-1 |
0.384 |
|
| 2022 |
Williams T, Ruiz AJ, Ruiz AM, Vo Q, Tsering W, Xu G, McFarland K, Giasson BI, Sullivan P, Borchelt DR, Chakrabarty P. Impact of APOE genotype on prion-type propagation of tauopathy. Acta Neuropathologica Communications. 10: 57. PMID 35440098 DOI: 10.1186/s40478-022-01359-y |
0.432 |
|
| 2022 |
McFarland KN, Chakrabarty P. Microglia in Alzheimer's Disease: a Key Player in the Transition Between Homeostasis and Pathogenesis. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 19: 186-208. PMID 35286658 DOI: 10.1007/s13311-021-01179-3 |
0.33 |
|
| 2022 |
McFarland KN, Chakrabarty P. Microglia in Alzheimer's Disease: a Key Player in the Transition Between Homeostasis and Pathogenesis. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 19: 186-208. PMID 35286658 DOI: 10.1007/s13311-021-01179-3 |
0.33 |
|
| 2022 |
McFarland KN, Chakrabarty P. Microglia in Alzheimer's Disease: a Key Player in the Transition Between Homeostasis and Pathogenesis. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 19: 186-208. PMID 35286658 DOI: 10.1007/s13311-021-01179-3 |
0.33 |
|
| 2021 |
Koller EJ, Ibanez KR, Vo Q, McFarland KN, Gonzalez De La Cruz E, Zobel L, Williams T, Xu G, Ryu D, Patel P, Giasson BI, Prokop S, Chakrabarty P. Combinatorial model of amyloid β and tau reveals synergy between amyloid deposits and tangle formation. Neuropathology and Applied Neurobiology. PMID 34825397 DOI: 10.1111/nan.12779 |
0.79 |
|
| 2021 |
Chakrabarty P, Borchelt DR. Astrocytic apoE4 and tau: Deadly combination for neurons. Cell Reports. Medicine. 2: 100316. PMID 34195681 DOI: 10.1016/j.xcrm.2021.100316 |
0.368 |
|
| 2021 |
McFarland KN, Ceballos C, Rosario A, Ladd T, Moore B, Golde G, Wang X, Allen M, Ertekin-Taner N, Funk CC, Robinson M, Baloni P, Rappaport N, Chakrabarty P, Golde TE. Microglia show differential transcriptomic response to Aβ peptide aggregates ex vivo and in vivo. Life Science Alliance. 4. PMID 34127518 DOI: 10.26508/lsa.202101108 |
0.334 |
|
| 2021 |
Levites Y, Funk C, Wang X, Chakrabarty P, McFarland KN, Bramblett B, O'Neal V, Liu X, Ladd T, Robinson M, Allen M, Carrasquillo MM, Dickson D, Cruz P, Ryu D, et al. Modulating innate immune activation states impacts the efficacy of specific Aβ immunotherapy. Molecular Neurodegeneration. 16: 32. PMID 33957936 DOI: 10.1186/s13024-021-00453-4 |
0.359 |
|
| 2021 |
Cockey SG, McFarland KN, Koller EJ, Brooks MMT, Gonzalez De La Cruz E, Cruz PE, Ceballos-Diaz C, Rosario AM, Levites YR, Borchelt DR, Golde TE, Giasson BI, Chakrabarty P. Il-10 signaling reduces survival in mouse models of synucleinopathy. Npj Parkinson's Disease. 7: 30. PMID 33741985 DOI: 10.1038/s41531-021-00169-8 |
0.758 |
|
| 2021 |
Beckman D, Chakrabarty P, Ott S, Dao A, Zhou E, Janssen WG, Donis-Cox K, Muller S, Kordower JH, Morrison JH. A novel tau-based rhesus monkey model of Alzheimer's pathogenesis. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33734581 DOI: 10.1002/alz.12318 |
0.349 |
|
| 2021 |
Li HD, Funk CC, McFarland K, Dammer EB, Allen M, Carrasquillo MM, Levties Y, Chakrabarty P, Burgess JD, Wang X, Dickson D, Seyfried NT, Duong DM, Lah JJ, Younkin SG, et al. Integrative functional genomic analysis of intron retention in human and mouse brain with Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33480174 DOI: 10.1002/alz.12254 |
0.344 |
|
| 2020 |
Williams T, Sorrentino Z, Weinrich M, Giasson BI, Chakrabarty P. Differential cross-seeding properties of tau and α-synuclein in mouse models of tauopathy and synucleinopathy. Brain Communications. 2: fcaa090. PMID 33094280 DOI: 10.1093/braincomms/fcaa090 |
0.378 |
|
| 2020 |
Koller EJ, Chakrabarty P. Tau-Mediated Dysregulation of Neuroplasticity and Glial Plasticity Frontiers in Molecular Neuroscience. 13. PMID 32973446 DOI: 10.3389/Fnmol.2020.00151 |
0.762 |
|
| 2020 |
Zu T, Guo S, Bardhi O, Ryskamp DA, Li J, Khoramian Tusi S, Engelbrecht A, Klippel K, Chakrabarty P, Nguyen L, Golde TE, Sonenberg N, Ranum LPW. Metformin inhibits RAN translation through PKR pathway and mitigates disease in ALS/FTD mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 32690681 DOI: 10.1073/Pnas.2005748117 |
0.36 |
|
| 2020 |
Chu WT, DeSimone JC, Riffe CJ, Liu H, Chakrabarty P, Giasson BI, Vedam-Mai V, Vaillancourt DE. Alpha-synuclein induces progressive changes in brain microstructure and sensory-evoked brain function that precedes locomotor decline. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32669353 DOI: 10.1523/Jneurosci.0189-20.2020 |
0.395 |
|
| 2020 |
Wan YW, Al-Ouran R, Mangleburg CG, Perumal TM, Lee TV, Allison K, Swarup V, Funk CC, Gaiteri C, Allen M, Wang M, Neuner SM, Kaczorowski CC, Philip VM, Howell GR, ... ... Chakrabarty P, et al. Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models. Cell Reports. 32: 107908. PMID 32668255 DOI: 10.1016/J.Celrep.2020.107908 |
0.479 |
|
| 2020 |
Xia Y, Prokop S, Gorion KM, Kim JD, Sorrentino ZA, Bell BM, Manaois AN, Chakrabarty P, Davies P, Giasson BI. Tau Ser208 phosphorylation promotes aggregation and reveals neuropathologic diversity in Alzheimer's disease and other tauopathies. Acta Neuropathologica Communications. 8: 88. PMID 32571418 DOI: 10.1186/S40478-020-00967-W |
0.496 |
|
| 2020 |
Xu G, Fromholt SE, Chakrabarty P, Zhu F, Liu X, Pace MC, Koh J, Golde TE, Levites Y, Lewis J, Borchelt DR. Diversity in Aβ deposit morphology and secondary proteome insolubility across models of Alzheimer-type amyloidosis. Acta Neuropathologica Communications. 8: 43. PMID 32252825 DOI: 10.1186/S40478-020-00911-Y |
0.505 |
|
| 2020 |
Williams T, Borchelt DR, Chakrabarty P. Therapeutic approaches targeting Apolipoprotein E function in Alzheimer's disease. Molecular Neurodegeneration. 15: 8. PMID 32005122 DOI: 10.1186/S13024-020-0358-9 |
0.43 |
|
| 2020 |
Koller EJ, Gonzalez De La Cruz E, Weinrich M, Williams T, Cruz PE, Ryu D, Golde TE, Sullivan PM, Lewis J, Borchelt DR, Chakrabarty P. Intracerebral Expression of AAV-APOE4 Is Not Sufficient to Alter Tau Burden in Two Distinct Models of Tauopathy. Molecular Neurobiology. PMID 31903524 DOI: 10.1007/S12035-019-01859-4 |
0.798 |
|
| 2020 |
Febo M, Perez PD, Ceballos-Diaz C, Colon-Perez LM, Zeng H, Ofori E, Golde TE, Vaillancourt DE, Chakrabarty P. Diffusion magnetic resonance imaging-derived free water detects neurodegenerative pattern induced by interferon-γ. Brain Structure & Function. PMID 31894407 DOI: 10.1007/S00429-019-02017-1 |
0.378 |
|
| 2019 |
Colon-Perez LM, Ibanez KR, Suarez M, Torroella K, Acuna K, Ofori E, Levites Y, Vaillancourt DE, Golde TE, Chakrabarty P, Febo M. Neurite orientation dispersion and density imaging reveals white matter and hippocampal microstructure changes produced by Interleukin-6 in the TgCRND8 mouse model of amyloidosis. Neuroimage. 202: 116138. PMID 31472250 DOI: 10.1016/J.Neuroimage.2019.116138 |
0.43 |
|
| 2019 |
Ofori E, DeKosky ST, Febo M, Colon-Perez L, Chakrabarty P, Duara R, Adjouadi M, Golde TE, Vaillancourt DE. Free-water imaging of the hippocampus is a sensitive marker of Alzheimer's disease. Neuroimage. Clinical. 24: 101985. PMID 31470214 DOI: 10.1016/J.Nicl.2019.101985 |
0.339 |
|
| 2019 |
Koller EJ, De La Cruz EG, Machula T, Ibanez KR, Lin WL, Williams T, Riffe CJ, Ryu D, Strang KH, Liu X, Janus C, Golde TE, Dickson D, Giasson BI, Chakrabarty P. Combining P301L and S320F tau variants produces a novel accelerated model of tauopathy. Human Molecular Genetics. PMID 31261380 DOI: 10.1093/Hmg/Ddz151 |
0.786 |
|
| 2019 |
Deyts C, Clutter M, Pierce N, Chakrabarty P, Ladd TB, Goddi A, Rosario AM, Cruz P, Vetrivel K, Wagner SL, Thinakaran G, Golde TE, Parent AT. APP-Mediated Signaling Prevents Memory Decline in Alzheimer's Disease Mouse Model. Cell Reports. 27: 1345-1355.e6. PMID 31042463 DOI: 10.1016/J.Celrep.2019.03.087 |
0.464 |
|
| 2019 |
Sorrentino ZA, Giasson BI, Chakrabarty P. α-Synuclein and astrocytes: tracing the pathways from homeostasis to neurodegeneration in Lewy body disease. Acta Neuropathologica. PMID 30798354 DOI: 10.1007/S00401-019-01977-2 |
0.375 |
|
| 2019 |
Croft CL, Cruz PE, Ryu DH, Ceballos-Diaz C, Strang KH, Woody BM, Lin WL, Deture M, Rodríguez-Lebrón E, Dickson DW, Chakrabarty P, Levites Y, Giasson BI, Golde TE. rAAV-based brain slice culture models of Alzheimer's and Parkinson's disease inclusion pathologies. The Journal of Experimental Medicine. PMID 30770411 DOI: 10.1084/Jem.20182184 |
0.494 |
|
| 2019 |
Magno L, Lessard CB, Martins M, Lang V, Cruz P, Asi Y, Katan M, Bilsland J, Lashley T, Chakrabarty P, Golde TE, Whiting PJ. Alzheimer's disease phospholipase C-gamma-2 (PLCG2) protective variant is a functional hypermorph. Alzheimer's Research & Therapy. 11: 16. PMID 30711010 DOI: 10.1186/S13195-019-0469-0 |
0.365 |
|
| 2018 |
Audrain M, Haure-Mirande JV, Wang M, Kim SH, Fanutza T, Chakrabarty P, Fraser P, St George-Hyslop PH, Golde TE, Blitzer RD, Schadt EE, Zhang B, Ehrlich ME, Gandy S. Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in a tauopathy mouse model reduces C1q and normalizes clinical phenotype while increasing spread and state of phosphorylation of tau. Molecular Psychiatry. PMID 30283031 DOI: 10.1038/S41380-018-0258-3 |
0.492 |
|
| 2018 |
Sorrentino ZA, Xia Y, Funk C, Riffe CJ, Rutherford NJ, Diaz CC, Sacino AN, Price ND, Golde TE, Giasson BI, Chakrabarty P. Motor neuron loss and neuroinflammation in a model of α-synuclein-induced neurodegeneration. Neurobiology of Disease. PMID 30195075 DOI: 10.1016/J.Nbd.2018.09.005 |
0.43 |
|
| 2018 |
Chakrabarty P, Li A, Ladd TB, Strickland MR, Koller EJ, Burgess JD, Funk CC, Cruz PE, Allen M, Yaroshenko M, Wang X, Younkin C, Reddy J, Lohrer B, Mehrke L, et al. TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer's disease. The Journal of Experimental Medicine. PMID 30158114 DOI: 10.1084/Jem.20180484 |
0.773 |
|
| 2018 |
Croft CL, Moore BD, Ran Y, Chakrabarty P, Levites Y, Golde TE, Giasson BI. Novel monoclonal antibodies targeting the microtubule-binding domain of human tau. Plos One. 13: e0195211. PMID 29608591 DOI: 10.1371/Journal.Pone.0195211 |
0.48 |
|
| 2018 |
Koller EJ, Cruz EGDL, Gaines KD, Machula TA, Strang KH, Liu X, Riffe CJ, Ryu D, Janus C, Golde TE, Giasson BI, Chakrabarty P. P3-091: Modeling Tauopathy Using Aav-Mediated Somatic Brain Transgenesis Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1447 |
0.303 |
|
| 2017 |
Strang KH, Croft CL, Sorrentino ZA, Chakrabarty P, Golde TE, Giasson BI. Distinct differences in prion-like seeding and aggregation between tau protein variants provide mechanistic insights into tauopathies. The Journal of Biological Chemistry. PMID 29259137 DOI: 10.1074/Jbc.M117.815357 |
0.49 |
|
| 2017 |
Strickland MR, Koller EJ, Deng DZ, Ceballos-Diaz C, Golde TE, Chakrabarty P. Ifngr1 and Stat1 mediated canonical Ifn-γ signaling drives nigrostriatal degeneration. Neurobiology of Disease. 110: 133-141. PMID 29196213 DOI: 10.1016/J.Nbd.2017.11.007 |
0.758 |
|
| 2017 |
Allen M, Wang X, Burgess JD, Watzlawik J, Serie DJ, Younkin CS, Nguyen T, Malphrus KG, Lincoln S, Carrasquillo MM, Ho C, Chakrabarty P, Strickland S, Murray ME, Swarup V, et al. Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29107053 DOI: 10.1016/J.Jalz.2017.09.012 |
0.446 |
|
| 2017 |
Verbeeck C, Carrano A, Chakrabarty P, Jankowsky JL, Das P. Combination of Aβ Suppression and Innate Immune Activation in the Brain Significantly Attenuates Amyloid Plaque Deposition. The American Journal of Pathology. PMID 28919107 DOI: 10.1016/J.Ajpath.2017.08.010 |
0.739 |
|
| 2017 |
Dhillon JS, Riffe C, Moore BD, Ran Y, Chakrabarty P, Golde TE, Giasson BI. A novel panel of α-synuclein antibodies reveal distinctive staining profiles in synucleinopathies. Plos One. 12: e0184731. PMID 28910367 DOI: 10.1371/Journal.Pone.0184731 |
0.376 |
|
| 2017 |
Strang KH, Goodwin MS, Riffe C, Moore BD, Chakrabarty P, Levites Y, Golde TE, Giasson BI. Generation and characterization of new monoclonal antibodies targeting the PHF1 and AT8 epitopes on human tau. Acta Neuropathologica Communications. 5: 58. PMID 28760159 DOI: 10.1186/S40478-017-0458-0 |
0.479 |
|
| 2017 |
Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, ... ... Chakrabarty P, et al. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nature Genetics. PMID 28714976 DOI: 10.1038/Ng.3916 |
0.363 |
|
| 2017 |
Prasad T, Zhu P, Verma A, Chakrabarty P, Rosario AM, Golde TE, Li Q. Amyloid β peptides overexpression in retinal pigment epithelial cells via AAV-mediated gene transfer mimics AMD-like pathology in mice. Scientific Reports. 7: 3222. PMID 28607377 DOI: 10.1038/S41598-017-03397-2 |
0.483 |
|
| 2017 |
Sorrentino ZA, Brooks MMT, Hudson V, Rutherford NJ, Golde TE, Giasson BI, Chakrabarty P. Intrastriatal injection of α-synuclein can lead to widespread synucleinopathy independent of neuroanatomic connectivity. Molecular Neurodegeneration. 12: 40. PMID 28552073 DOI: 10.1186/S13024-017-0182-Z |
0.364 |
|
| 2017 |
Koller EJ, Brooks MM, Golde TE, Giasson BI, Chakrabarty P. Inflammatory pre-conditioning restricts the seeded induction of α-synuclein pathology in wild type mice. Molecular Neurodegeneration. 12: 1. PMID 28049533 DOI: 10.1186/S13024-016-0142-Z |
0.759 |
|
| 2017 |
Croft CL, Cruz PE, Goodwin MS, Ceballos-Diaz C, Strang K, Chakrabarty P, Levites Y, Giasson BI, Golde TE. [P4-094]: TARGETING TAU AGGREGATION IN BRAIN SLICE CULTURE MODELS OF TAUOPATHIES Alzheimer's & Dementia. 13: P1294-P1294. DOI: 10.1016/J.Jalz.2017.06.1959 |
0.363 |
|
| 2016 |
Sacino AN, Brooks MM, Chakrabarty P, Saha K, Khoshbouei H, Golde TE, Giasson BI. Proteolysis of α-Synuclein Fibrils in the Lysosomal Pathway Limits Induction of Inclusion Pathology. Journal of Neurochemistry. PMID 27424880 DOI: 10.1111/Jnc.13743 |
0.367 |
|
| 2016 |
Rosario AM, Cruz PE, Ceballos-Diaz C, Strickland MR, Siemienski Z, Pardo M, Schob KL, Li A, Aslanidi GV, Srivastava A, Golde TE, Chakrabarty P. Microglia-specific targeting by novel capsid-modified AAV6 vectors. Molecular Therapy. Methods & Clinical Development. 3: 16026. PMID 27308302 DOI: 10.1038/Mtm.2016.26 |
0.411 |
|
| 2015 |
Sacino AN, Ayers JI, Brooks MM, Chakrabarty P, Hudson VJ, Howard JK, Golde TE, Giasson BI, Borchelt DR. Non-prion-type transmission in A53T α-synuclein transgenic mice: a normal component of spinal homogenates from naïve non-transgenic mice induces robust α-synuclein pathology. Acta Neuropathologica. PMID 26541429 DOI: 10.1007/S00401-015-1505-1 |
0.403 |
|
| 2015 |
Zhao Y, Tseng IC, Heyser CJ, Rockenstein E, Mante M, Adame A, Zheng Q, Huang T, Wang X, Arslan PE, Chakrabarty P, Wu C, Bu G, Mobley WC, Zhang YW, et al. Appoptosin-Mediated Caspase Cleavage of Tau Contributes to Progressive Supranuclear Palsy Pathogenesis. Neuron. 87: 963-75. PMID 26335643 DOI: 10.1016/J.Neuron.2015.08.020 |
0.465 |
|
| 2015 |
Li A, Ceballos-Diaz C, DiNunno N, Levites Y, Cruz PE, Lewis J, Golde TE, Chakrabarty P. IFN-γ promotes τ phosphorylation without affecting mature tangles. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26156074 DOI: 10.1096/Fj.15-275834 |
0.423 |
|
| 2015 |
Ceballos-Diaz C, Rosario AM, Park HJ, Chakrabarty P, Sacino A, Cruz PE, Siemienski Z, Lara N, Moran C, Ravelo N, Golde TE, McFarland NR. Viral expression of ALS-linked ubiquilin-2 mutants causes inclusion pathology and behavioral deficits in mice. Molecular Neurodegeneration. 10: 25. PMID 26152284 DOI: 10.1186/S13024-015-0026-7 |
0.409 |
|
| 2015 |
Chakrabarty P, Hudson Iii VJ, Sacino AN, Brooks MM, D'Alton S, Lewis J, Golde TE, Giasson BI. Inefficient induction and spread of seeded tau pathology in P301L mouse model of tauopathy suggests inherent physiological barriers to transmission. Acta Neuropathologica. 130: 303-5. PMID 25982997 DOI: 10.1007/S00401-015-1444-X |
0.483 |
|
| 2015 |
Chakrabarty P, Li A, Ceballos-Diaz C, Eddy JA, Funk CC, Moore B, DiNunno N, Rosario AM, Cruz PE, Verbeeck C, Sacino A, Nix S, Janus C, Price ND, Das P, et al. IL-10 alters immunoproteostasis in APP mice, increasing plaque burden and worsening cognitive behavior. Neuron. 85: 519-33. PMID 25619653 DOI: 10.1016/J.Neuron.2014.11.020 |
0.46 |
|
| 2015 |
Prasad T, Zhu P, Verma A, Chakrabarty P, Rosario AM, Golde TE, Li Q. 391. Increased Levels of Amyloid β Peptides in RPE via AAV-Mediated Gene Transfer Mimics AMD-Like Pathology in Mice Molecular Therapy. 23: S155. DOI: 10.1016/S1525-0016(16)34000-X |
0.473 |
|
| 2015 |
Chakrabarty P, Brooks M, Hudson V, Levites Y, Giasson BI, Golde T. O2-05-01: IL-10 modifies disease progression and pathology in a mouse model of alpha synucleinopathy Alzheimer's & Dementia. 11: P182-P183. DOI: 10.1016/J.Jalz.2015.07.154 |
0.325 |
|
| 2015 |
Golde T, Levites Y, Cruz PE, Rosario AM, Chakrabarty P, Moran C, Liu X, Ceballos-Diaz C, Moore B, Price ND, Funk C. O1-11-03: Modulating chemokine signaling in preclinical Alzheimer's disease models Alzheimer's & Dementia. 11: P157-P157. DOI: 10.1016/J.Jalz.2015.07.089 |
0.358 |
|
| 2014 |
Chakrabarty P, Tianbai L, Moore B, Rosario A, Cruz P, Ladd T, Ceballos-Diaz C, Golde T. P1-095: MODULATING INNATE IMMUNITY IN ALZHEIMER'S DISEASE Alzheimer's & Dementia. 10: P336-P337. DOI: 10.1016/J.Jalz.2014.05.331 |
0.376 |
|
| 2013 |
Chakrabarty P, Rosario A, Cruz P, Siemienski Z, Ceballos-Diaz C, Crosby K, Jansen K, Borchelt DR, Kim JY, Jankowsky JL, Golde TE, Levites Y. Capsid serotype and timing of injection determines AAV transduction in the neonatal mice brain. Plos One. 8: e67680. PMID 23825679 DOI: 10.1371/Journal.Pone.0067680 |
0.645 |
|
| 2013 |
Golde TE, Streit WJ, Chakrabarty P. Alzheimer's disease risk alleles in TREM2 illuminate innate immunity in Alzheimer's disease. Alzheimer's Research & Therapy. 5: 24. PMID 23692967 DOI: 10.1186/Alzrt178 |
0.46 |
|
| 2013 |
Clippinger AK, D'Alton S, Lin WL, Gendron TF, Howard J, Borchelt DR, Cannon A, Carlomagno Y, Chakrabarty P, Cook C, Golde TE, Levites Y, Ranum L, Schultheis PJ, Xu G, et al. Robust cytoplasmic accumulation of phosphorylated TDP-43 in transgenic models of tauopathy. Acta Neuropathologica. 126: 39-50. PMID 23666556 DOI: 10.1007/S00401-013-1123-8 |
0.534 |
|
| 2013 |
Kim J, Chakrabarty P, Hanna A, March A, Dickson DW, Borchelt DR, Golde T, Janus C. Normal cognition in transgenic BRI2-Aβ mice. Molecular Neurodegeneration. 8: 15. PMID 23663320 DOI: 10.1186/1750-1326-8-15 |
0.456 |
|
| 2013 |
Golde TE, Felsenstein K, Chakrabarty P, Li A, Moore B, In JJ, Cruz P, Price A, Borchelt D, Janus C, Cebballos-Diaz C, Rosario A. Harnessing endogenous pathways and metabolites to treat or prevent neurodegenerative disease Molecular Neurodegeneration. 8. DOI: 10.1186/1750-1326-8-S1-O36 |
0.451 |
|
| 2012 |
Das P, Verbeeck C, Minter L, Chakrabarty P, Felsenstein K, Kukar T, Maharvi G, Fauq A, Osborne BA, Golde TE. Transient pharmacologic lowering of Aβ production prior to deposition results in sustained reduction of amyloid plaque pathology. Molecular Neurodegeneration. 7: 39. PMID 22892055 DOI: 10.1186/1750-1326-7-39 |
0.38 |
|
| 2012 |
Chakrabarty P, Tianbai L, Herring A, Ceballos-Diaz C, Das P, Golde TE. Hippocampal expression of murine IL-4 results in exacerbation of amyloid deposition. Molecular Neurodegeneration. 7: 36. PMID 22838967 DOI: 10.1186/1750-1326-7-36 |
0.528 |
|
| 2012 |
Moore BD, Chakrabarty P, Levites Y, Kukar TL, Baine AM, Moroni T, Ladd TB, Das P, Dickson DW, Golde TE. Overlapping profiles of Aβ peptides in the Alzheimer's disease and pathological aging brains. Alzheimer's Research & Therapy. 4: 18. PMID 22621179 DOI: 10.1186/Alzrt121 |
0.407 |
|
| 2011 |
Chakrabarty P, Ceballos-Diaz C, Lin WL, Beccard A, Jansen-West K, McFarland NR, Janus C, Dickson D, Das P, Golde TE. Interferon-γ induces progressive nigrostriatal degeneration and basal ganglia calcification. Nature Neuroscience. 14: 694-6. PMID 21572432 DOI: 10.1038/Nn.2829 |
0.335 |
|
| 2011 |
Chakrabarty P, Herring A, Ceballos-Diaz C, Das P, Golde TE. Hippocampal expression of murine TNFα results in attenuation of amyloid deposition in vivo. Molecular Neurodegeneration. 6: 16. PMID 21324189 DOI: 10.1186/1750-1326-6-16 |
0.516 |
|
| 2011 |
Chakrabarty P, Ceballos-Diaz C, Beccard A, Cruz P, Dickson D, Das P, Golde T. P2-326: Towards a comprehensive analysis of the role of inflammatory mediators on Alzheimer's like pathology in pre-clinical mouse models Alzheimer's & Dementia. 7: S413-S414. DOI: 10.1016/J.Jalz.2011.05.1202 |
0.397 |
|
| 2010 |
Chakrabarty P, Ceballos-Diaz C, Beccard A, Janus C, Dickson D, Golde TE, Das P. IFN-gamma promotes complement expression and attenuates amyloid plaque deposition in amyloid beta precursor protein transgenic mice. Journal of Immunology (Baltimore, Md. : 1950). 184: 5333-43. PMID 20368278 DOI: 10.4049/Jimmunol.0903382 |
0.471 |
|
| 2010 |
Chakrabarty P, Jansen-West K, Beccard A, Ceballos-Diaz C, Levites Y, Verbeeck C, Zubair AC, Dickson D, Golde TE, Das P. Massive gliosis induced by interleukin-6 suppresses Abeta deposition in vivo: evidence against inflammation as a driving force for amyloid deposition. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 548-59. PMID 19825975 DOI: 10.1096/Fj.09-141754 |
0.457 |
|
| 2010 |
Chakrabarty P, Beccard A, Cellallos-Diaz C, Golde T, Das P. P1-320: AAV-mediated expression of anti-inflammatory cytokines IL-10 and IL-4 significantly exacerbate amyloid pathology in the brains of APP TgCRND8 mice Alzheimer's & Dementia. 6: S266-S266. DOI: 10.1016/J.Jalz.2010.05.873 |
0.387 |
|
| 2008 |
Chakrabarty P, Nimcheski K, Golde TE, Jansen K, Verbeeck C, Das P. P3-354: Role of IL-6-mediated chronic neuroinflammation on amyloid pathology Alzheimer's & Dementia. 4: T625-T625. DOI: 10.1016/J.Jalz.2008.05.1924 |
0.351 |
|
| 2007 |
Park KH, Hallows JL, Chakrabarty P, Davies P, Vincent I. Conditional neuronal simian virus 40 T antigen expression induces Alzheimer-like tau and amyloid pathology in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 2969-78. PMID 17360920 DOI: 10.1523/Jneurosci.0186-07.2007 |
0.537 |
|
| 2006 |
Das P, Smithson LA, Price RW, Holloway VM, Levites Y, Chakrabarty P, Golde TE. Interleukin-1 receptor 1 knockout has no effect on amyloid deposition in Tg2576 mice and does not alter efficacy following Abeta immunotherapy. Journal of Neuroinflammation. 3: 17. PMID 16872492 DOI: 10.1186/1742-2094-3-17 |
0.404 |
|
| 2006 |
Funk CC, Richards MA, Shannon P, Donovan-Maiye R, Rappaport N, Robinson M, Allen M, Carrasquillo MM, Chakrabarty P, McFarland K, Jung SC, Rodriguez A, Ertekin-Taner N, Golde TE, Hood L, et al. O3-03-01: MECHANISTIC AND DIRECTIONAL TRANSCRIPTIONAL REGULATORY NETWORKS IN ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P1014-P1015. DOI: 10.1016/J.Jalz.2018.06.2782 |
0.319 |
|
| 2006 |
Golde TE, Jansen KR, Nyborg AC, Das P, Chakrabarty P, Smithson LA, Kim J, Levties Y. P1-005: RAAV vectors to rapidly modify and model AD pathology in mice, rats, and guinea pigs Alzheimer's & Dementia. 2: S95-S95. DOI: 10.1016/J.Jalz.2006.05.380 |
0.406 |
|
| 2004 |
Zhang M, Li J, Chakrabarty P, Bu B, Vincent I. Cyclin-dependent kinase inhibitors attenuate protein hyperphosphorylation, cytoskeletal lesion formation, and motor defects in Niemann-Pick Type C mice. The American Journal of Pathology. 165: 843-53. PMID 15331409 DOI: 10.1016/S0002-9440(10)63347-0 |
0.426 |
|
| 2004 |
Vincent I, Zhang M, Li J, Chakrabarty P, Park K, Hallows J. S1-04-01 Cdk5: a hierarchical and negative, but not direct and positive, effector of tau phosphorylation Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80022-8 |
0.33 |
|
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