David L. Sulzer - Publications

Affiliations: 
Columbia University College of Physicians and Surgeons, New York, NY, United States 
Area:
synaptic physiology and cell biology of the basal ganglia in health and disease
Website:
http://www.sulzerlab.org

174 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Cassidy CM, Zucca FA, Girgis RR, Baker SC, Weinstein JJ, Sharp ME, Bellei C, Valmadre A, Vanegas N, Kegeles LS, Brucato G, Jung Kang U, Sulzer D, Zecca L, Abi-Dargham A, et al. Neuromelanin-sensitive MRI as a noninvasive proxy measure of dopamine function in the human brain. Proceedings of the National Academy of Sciences of the United States of America. PMID 30796187 DOI: 10.1073/pnas.1807983116  0.76
2019 Fahn S, Sulzer D, Kang UJ, Bressman S. In memoriam: Robert E. Burke, MD, 1949-2018. Movement Disorders : Official Journal of the Movement Disorder Society. 34: 35-40. PMID 30653722 DOI: 10.1002/mds.27612  0.32
2018 Meszaros J, Cheung T, Erler MM, Kang UJ, Sames D, Kellendonk C, Sulzer D. Evoked transients of pH-sensitive fluorescent false neurotransmitter reveal dopamine hot spots in the globus pallidus. Elife. 7. PMID 30566076 DOI: 10.7554/eLife.42383  0.32
2018 Monzani E, Nicolis S, Dell'Acqua S, Capucciati A, Bacchella C, Zucca F, Mosharov E, Sulzer D, Zecca L, Casella L. Dopamine, oxidative stress and protein-quinone modifications in Parkinson's and other neurodegenerative diseases. Angewandte Chemie (International Ed. in English). PMID 30536578 DOI: 10.1002/anie.201811122  0.76
2018 Hoffman BU, Baba Y, Griffith TN, Mosharov EV, Woo SH, Roybal DD, Karsenty G, Patapoutian A, Sulzer D, Lumpkin EA. Merkel Cells Activate Sensory Neural Pathways through Adrenergic Synapses. Neuron. PMID 30415995 DOI: 10.1016/j.neuron.2018.10.034  0.44
2018 Lieberman OJ, McGuirt AF, Mosharov EV, Pigulevskiy I, Hobson BD, Choi S, Frier MD, Santini E, Borgkvist A, Sulzer D. Dopamine Triggers the Maturation of Striatal Spiny Projection Neuron Excitability during a Critical Period. Neuron. PMID 30057204 DOI: 10.1016/j.neuron.2018.06.044  0.44
2018 Dunn M, Henke A, Clark S, Kovalyova Y, Kempadoo KA, Karpowicz RJ, Kandel ER, Sulzer D, Sames D. Designing a norepinephrine optical tracer for imaging individual noradrenergic synapses and their activity in vivo. Nature Communications. 9: 2838. PMID 30026491 DOI: 10.1038/s41467-018-05075-x  0.36
2018 Zucca FA, Vanna R, Cupaioli FA, Bellei C, De Palma A, Di Silvestre D, Mauri P, Grassi S, Prinetti A, Casella L, Sulzer D, Zecca L. Neuromelanin organelles are specialized autolysosomes that accumulate undegraded proteins and lipids in aging human brain and are likely involved in Parkinson's disease. Npj Parkinson's Disease. 4: 17. PMID 29900402 DOI: 10.1038/s41531-018-0050-8  0.76
2018 Sulzer D, Cassidy C, Horga G, Kang UJ, Fahn S, Casella L, Pezzoli G, Langley J, Hu XP, Zucca FA, Isaias IU, Zecca L. Neuromelanin detection by magnetic resonance imaging (MRI) and its promise as a biomarker for Parkinson's disease. Npj Parkinson's Disease. 4: 11. PMID 29644335 DOI: 10.1038/s41531-018-0047-3  0.76
2018 Lautenschläger J, Mosharov EV, Kanter E, Sulzer D, Kaminski Schierle GS. An Easy-to-Implement Protocol for Preparing Postnatal Ventral Mesencephalic Cultures. Frontiers in Cellular Neuroscience. 12: 44. PMID 29556177 DOI: 10.3389/fncel.2018.00044  0.44
2018 Fischer KD, Houston ACW, Desai RI, Doyle MR, Bergman J, Mian M, Mannix R, Sulzer DL, Choi SJ, Mosharov EV, Hodgson NW, Bechtholt A, Miczek KA, Rosenberg PA. Behavioral phenotyping and dopamine dynamics in mice with conditional deletion of the glutamate transporter GLT-1 in neurons: resistance to the acute locomotor effects of amphetamine. Psychopharmacology. PMID 29468294 DOI: 10.1007/s00213-018-4848-1  0.44
2018 Bamford NS, Wightman RM, Sulzer D. Dopamine's Effects on Corticostriatal Synapses during Reward-Based Behaviors. Neuron. 97: 494-510. PMID 29420932 DOI: 10.1016/j.neuron.2018.01.006  0.44
2017 Henke A, Kovalyova Y, Dunn M, Dreier D, Gubernator NG, Dincheva I, Hwu C, Sebej P, Ansorge MS, Sulzer D, Sames D. Toward Serotonin Fluorescent False Neurotransmitters: Development of Fluorescent Dual Serotonin and Vesicular Monoamine Transporter Substrates for Visualizing Serotonin Neurons. Acs Chemical Neuroscience. PMID 29281252 DOI: 10.1021/acschemneuro.7b00320  0.32
2017 Dunn M, Boltaev U, Beskow A, Pampou S, Realubit R, Meira T, Silva JV, Reeb R, Karan C, Jockusch S, Sulzer D, Chang YT, Sames D, Waites C. Identification of fluorescent small molecule compounds for synaptic labeling by image-based, high-content screening. Acs Chemical Neuroscience. PMID 29215865 DOI: 10.1021/acschemneuro.7b00263  0.32
2017 Lieberman OJ, Choi SJ, Kanter E, Saverchenko A, Frier MD, Fiore GM, Wu M, Kondapalli J, Zampese E, Surmeier DJ, Sulzer D, Mosharov EV. α-Synuclein-Dependent Calcium Entry Underlies Differential Sensitivity of Cultured SN and VTA Dopaminergic Neurons to a Parkinsonian Neurotoxin. Eneuro. 4. PMID 29177188 DOI: 10.1523/ENEURO.0167-17.2017  0.44
2017 Borgkvist A, Lieberman OJ, Sulzer D. Synaptic plasticity may underlie l-DOPA induced dyskinesia. Current Opinion in Neurobiology. 48: 71-78. PMID 29125979 DOI: 10.1016/j.conb.2017.10.021  0.44
2017 Francardo V, Schmitz Y, Sulzer D, Angela Cenci M. Neuroprotection and neurorestoration as experimental therapeutics for Parkinson's disease. Experimental Neurology. PMID 28988910 DOI: 10.1016/j.expneurol.2017.10.001  0.36
2017 Aguilar JI, Dunn M, Mingote S, Karam CS, Farino ZJ, Sonders MS, Choi SJ, Grygoruk A, Zhang Y, Cela C, Choi BJ, Flores J, Freyberg RJ, McCabe BD, Mosharov EV, ... ... Sulzer D, et al. Neuronal Depolarization Drives Increased Dopamine Synaptic Vesicle Loading via VGLUT. Neuron. PMID 28823729 DOI: 10.1016/j.neuron.2017.07.038  0.48
2017 Mingote S, Chuhma N, Kalmbach A, Thomsen GM, Wang Y, Mihali A, Sferrazza CE, Zucker-Scharff I, Siena AC, Welch MG, Lizardi-Ortiz J, Sulzer D, Moore H, Gaisler-Salomon I, Rayport S. Dopamine neuron dependent behaviorsmediated by glutamate cotransmission. Elife. 6. PMID 28703706 DOI: 10.7554/eLife.27566  0.48
2016 Kempadoo KA, Mosharov EV, Choi SJ, Sulzer D, Kandel ER. Dopamine release from the locus coeruleus to the dorsal hippocampus promotes spatial learning and memory. Proceedings of the National Academy of Sciences of the United States of America. PMID 27930324 DOI: 10.1073/pnas.1616515114  0.44
2016 Chung SY, Kishinevsky S, Mazzulli JR, Graziotto J, Mrejeru A, Mosharov EV, Puspita L, Valiulahi P, Sulzer D, Milner TA, Taldone T, Krainc D, Studer L, Shim JW. Parkin and PINK1 Patient iPSC-Derived Midbrain Dopamine Neurons Exhibit Mitochondrial Dysfunction and α-Synuclein Accumulation. Stem Cell Reports. PMID 27641647 DOI: 10.1016/j.stemcr.2016.08.012  0.92
2016 Avegno EM, Salling MC, Borgkvist A, Mrejeru A, Whitebirch AC, Margolis EB, Sulzer D, Harrison NL. Voluntary adolescent drinking enhances excitation by low levels of alcohol in a subset of dopaminergic neurons in the ventral tegmental area. Neuropharmacology. PMID 27475082 DOI: 10.1016/j.neuropharm.2016.07.031  0.92
2016 Kharkwal G, Brami-Cherrier K, Lizardi-Ortiz JE, Nelson AB, Ramos M, Del Barrio D, Sulzer D, Kreitzer AC, Borrelli E. Parkinsonism Driven by Antipsychotics Originates from Dopaminergic Control of Striatal Cholinergic Interneurons. Neuron. 91: 67-78. PMID 27387649 DOI: 10.1016/j.neuron.2016.06.014  0.32
2016 Pereira DB, Schmitz Y, Mészáros J, Merchant P, Hu G, Li S, Henke A, Lizardi-Ortiz JE, Karpowicz RJ, Morgenstern TJ, Sonders MS, Kanter E, Rodriguez PC, Mosharov EV, Sames D, ... Sulzer D, et al. Fluorescent false neurotransmitter reveals functionally silent dopamine vesicle clusters in the striatum. Nature Neuroscience. PMID 26900925 DOI: 10.1038/nn.4252  0.92
2016 Freyberg Z, Sonders MS, Aguilar JI, Hiranita T, Karam CS, Flores J, Pizzo AB, Zhang Y, Farino ZJ, Chen A, Martin CA, Kopajtic TA, Fei H, Hu G, Lin YY, ... ... Sulzer D, et al. Mechanisms of amphetamine action illuminated through optical monitoring of dopamine synaptic vesicles in Drosophila brain. Nature Communications. 7: 10652. PMID 26879809 DOI: 10.1038/ncomms10652  0.92
2015 Divito CB, Steece-Collier K, Case DT, Williams SP, Stancati JA, Zhi L, Rubio ME, Sortwell CE, Collier TJ, Sulzer D, Edwards RH, Zhang H, Seal RP. Loss of VGLUT3 Produces Circadian-Dependent Hyperdopaminergia and Ameliorates Motor Dysfunction and l-Dopa-Mediated Dyskinesias in a Model of Parkinson's Disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 14983-99. PMID 26558771 DOI: 10.1523/JNEUROSCI.2124-15.2015  0.92
2015 Zucca FA, Segura-Aguilar J, Ferrari E, Muñoz P, Paris I, Sulzer D, Sarna T, Casella L, Zecca L. Interactions of iron, dopamine and neuromelanin pathways in brain aging and Parkinson's disease. Progress in Neurobiology. PMID 26455458 DOI: 10.1016/j.pneurobio.2015.09.012  0.92
2015 Borgkvist A, Avegno EM, Wong MY, Kheirbek MA, Sonders MS, Hen R, Sulzer D. Loss of Striatonigral GABAergic Presynaptic Inhibition Enables Motor Sensitization in Parkinsonian Mice. Neuron. 87: 976-88. PMID 26335644 DOI: 10.1016/j.neuron.2015.08.022  0.92
2015 Merchant P, Sulzer D, Sames D. Synaptic optical imaging platforms: Examining pharmacological modulation of neurotransmitter release at discrete synapses. Neuropharmacology. PMID 25837712 DOI: 10.1016/j.neuropharm.2015.03.013  0.92
2015 Mrejeru A, Martí-Prats L, Avegno EM, Harrison NL, Sulzer D. A subset of ventral tegmental area dopamine neurons responds to acute ethanol. Neuroscience. 290: 649-58. PMID 25660505 DOI: 10.1016/j.neuroscience.2014.12.081  0.92
2015 Wong MY, Borgkvist A, Choi SJ, Mosharov EV, Bamford NS, Sulzer D. Dopamine-dependent corticostriatal synaptic filtering regulates sensorimotor behavior. Neuroscience. 290: 594-607. PMID 25637802 DOI: 10.1016/j.neuroscience.2015.01.022  0.92
2015 Choi SJ, Panhelainen A, Schmitz Y, Larsen KE, Kanter E, Wu M, Sulzer D, Mosharov EV. Changes in neuronal dopamine homeostasis following 1-methyl-4-phenylpyridinium (MPP+) exposure. The Journal of Biological Chemistry. 290: 6799-809. PMID 25596531 DOI: 10.1074/jbc.M114.631556  0.92
2015 Steinbeck JA, Choi SJ, Mrejeru A, Ganat Y, Deisseroth K, Sulzer D, Mosharov EV, Studer L. Optogenetics enables functional analysis of human embryonic stem cell-derived grafts in a Parkinson's disease model. Nature Biotechnology. 33: 204-9. PMID 25580598 DOI: 10.1038/nbt.3124  0.92
2015 Er JC, Leong C, Teoh CL, Yuan Q, Merchant P, Dunn M, Sulzer D, Sames D, Bhinge A, Kim D, Kim SM, Yoon MH, Stanton LW, Je SH, Yun SW, et al. NeuO: a fluorescent chemical probe for live neuron labeling. Angewandte Chemie (International Ed. in English). 54: 2442-6. PMID 25565332 DOI: 10.1002/anie.201408614  0.92
2015 Mosharov EV, Borgkvist A, Sulzer D. Presynaptic effects of levodopa and their possible role in dyskinesia. Movement Disorders : Official Journal of the Movement Disorder Society. 30: 45-53. PMID 25450307 DOI: 10.1002/mds.26103  0.92
2015 Cebrián C, Loike JD, Sulzer D. Neuroinflammation in Parkinson's disease animal models: a cell stress response or a step in neurodegeneration? Current Topics in Behavioral Neurosciences. 22: 237-70. PMID 25293443 DOI: 10.1007/7854_2014_356  0.92
2015 Borgkvist A, Avegno EM, Wong MY, Kheirbek MA, Sonders MS, Hen R, Sulzer D. Loss of Striatonigral GABAergic Presynaptic Inhibition Enables Motor Sensitization in Parkinsonian Mice Neuron. 87: 976-988. DOI: 10.1016/j.neuron.2015.08.022  0.92
2014 Woodard CM, Campos BA, Kuo SH, Nirenberg MJ, Nestor MW, Zimmer M, Mosharov EV, Sulzer D, Zhou H, Paull D, Clark L, Schadt EE, Sardi SP, Rubin L, Eggan K, et al. iPSC-derived dopamine neurons reveal differences between monozygotic twins discordant for Parkinson's disease. Cell Reports. 9: 1173-82. PMID 25456120 DOI: 10.1016/j.celrep.2014.10.023  0.92
2014 Cebrián C, Loike JD, Sulzer D. Neuronal MHC-I expression and its implications in synaptic function, axonal regeneration and Parkinson's and other brain diseases. Frontiers in Neuroanatomy. 8: 114. PMID 25352786 DOI: 10.3389/fnana.2014.00114  0.92
2014 Tang G, Gudsnuk K, Kuo SH, Cotrina ML, Rosoklija G, Sosunov A, Sonders MS, Kanter E, Castagna C, Yamamoto A, Yue Z, Arancio O, Peterson BS, Champagne F, Dwork AJ, ... ... Sulzer D, et al. Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits. Neuron. 83: 1131-43. PMID 25155956 DOI: 10.1016/j.neuron.2014.07.040  0.92
2014 Caraveo G, Auluck PK, Whitesell L, Chung CY, Baru V, Mosharov EV, Yan X, Ben-Johny M, Soste M, Picotti P, Kim H, Caldwell KA, Caldwell GA, Sulzer D, Yue DT, et al. Calcineurin determines toxic versus beneficial responses to α-synuclein. Proceedings of the National Academy of Sciences of the United States of America. 111: E3544-52. PMID 25122673 DOI: 10.1073/pnas.1413201111  0.92
2014 Gil-Pisa I, Cebrián C, Ortega JE, Meana JJ, Sulzer D. Cytokine pathway disruption in a mouse model of schizophrenia induced by Munc18-1a overexpression in the brain. Journal of Neuroinflammation. 11: 128. PMID 25069615 DOI: 10.1186/1742-2094-11-128  0.92
2014 Borgkvist A, Mosharov EV, Sulzer D. Calcium currents regulate dopamine autoreceptors. Brain : a Journal of Neurology. 137: 2113-5. PMID 25057130 DOI: 10.1093/brain/awu150  0.92
2014 Trudeau LE, Hnasko TS, Wallén-Mackenzie A, Morales M, Rayport S, Sulzer D. The multilingual nature of dopamine neurons. Progress in Brain Research. 211: 141-64. PMID 24968779 DOI: 10.1016/B978-0-444-63425-2.00006-4  0.92
2014 Cebrián C, Zucca FA, Mauri P, Steinbeck JA, Studer L, Scherzer CR, Kanter E, Budhu S, Mandelbaum J, Vonsattel JP, Zecca L, Loike JD, Sulzer D. MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration. Nature Communications. 5: 3633. PMID 24736453 DOI: 10.1038/ncomms4633  0.92
2014 Foster DJ, Gentry PR, Lizardi-Ortiz JE, Bridges TM, Wood MR, Niswender CM, Sulzer D, Lindsley CW, Xiang Z, Conn PJ. M5 receptor activation produces opposing physiological outcomes in dopamine neurons depending on the receptor's location. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 3253-62. PMID 24573284 DOI: 10.1523/JNEUROSCI.4896-13.2014  0.92
2014 Federici M, Latagliata EC, Ledonne A, Rizzo FR, Feligioni M, Sulzer D, Dunn M, Sames D, Gu H, Nisticò R, Puglisi-Allegra S, Mercuri NB. Paradoxical abatement of striatal dopaminergic transmission by cocaine and methylphenidate. The Journal of Biological Chemistry. 289: 264-74. PMID 24280216 DOI: 10.1074/jbc.M113.495499  0.92
2014 Zucca FA, Basso E, Cupaioli FA, Ferrari E, Sulzer D, Casella L, Zecca L. Neuromelanin of the human substantia nigra: an update. Neurotoxicity Research. 25: 13-23. PMID 24155156 DOI: 10.1007/s12640-013-9435-y  0.92
2014 Tang G, Gudsnuk K, Kuo SH, Cotrina ML, Rosoklija G, Sosunov A, Sonders MS, Kanter E, Castagna C, Yamamoto A, Yue Z, Arancio O, Peterson BS, Champagne F, Dwork AJ, ... ... Sulzer D, et al. Erratam to Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits[Neuron, 83, (2014), 1131-1143] Neuron. 83: 1482. DOI: 10.1016/j.neuron.2014.09.001  0.92
2014 Tang G, Sulzer D. Cargo Recognition Failure Underlies Macroautophagy Defects in Huntington's Disease Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging. 3: 147-162. DOI: 10.1016/B978-0-12-405529-2.00010-X  0.92
2013 Schmitz Y, Castagna C, Mrejeru A, Lizardi-Ortiz JE, Klein Z, Lindsley CW, Sulzer D. Glycine transporter-1 inhibition promotes striatal axon sprouting via NMDA receptors in dopamine neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 16778-89. PMID 24133278 DOI: 10.1523/JNEUROSCI.3041-12.2013  0.92
2013 Sames D, Dunn M, Karpowicz RJ, Sulzer D. Visualizing neurotransmitter secretion at individual synapses. Acs Chemical Neuroscience. 4: 648-51. PMID 23862751 DOI: 10.1021/cn4000956  0.92
2013 Hu G, Henke A, Karpowicz RJ, Sonders MS, Farrimond F, Edwards R, Sulzer D, Sames D. New fluorescent substrate enables quantitative and high-throughput examination of vesicular monoamine transporter 2 (VMAT2). Acs Chemical Biology. 8: 1947-54. PMID 23859623 DOI: 10.1021/cb400259n  0.92
2013 Karpowicz RJ, Dunn M, Sulzer D, Sames D. APP+, a fluorescent analogue of the neurotoxin MPP+, is a marker of catecholamine neurons in brain tissue, but not a fluorescent false neurotransmitter. Acs Chemical Neuroscience. 4: 858-69. PMID 23647019 DOI: 10.1021/cn400038u  0.92
2013 Sulzer D, Surmeier DJ. Neuronal vulnerability, pathogenesis, and Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 28: 715-24. PMID 23589357 DOI: 10.1002/mds.25187  0.92
2013 Kuo SH, Tang G, Louis ED, Ma K, Babji R, Balatbat M, Cortes E, Vonsattel JP, Yamamoto A, Sulzer D, Faust PL. Lingo-1 expression is increased in essential tremor cerebellum and is present in the basket cell pinceau. Acta Neuropathologica. 125: 879-89. PMID 23543187 DOI: 10.1007/s00401-013-1108-7  0.92
2013 Orenstein SJ, Kuo SH, Tasset I, Arias E, Koga H, Fernandez-Carasa I, Cortes E, Honig LS, Dauer W, Consiglio A, Raya A, Sulzer D, Cuervo AM. Interplay of LRRK2 with chaperone-mediated autophagy. Nature Neuroscience. 16: 394-406. PMID 23455607 DOI: 10.1038/nn.3350  0.92
2013 Sun X, Liu J, Crary JF, Malagelada C, Sulzer D, Greene LA, Levy OA. ATF4 protects against neuronal death in cellular Parkinson's disease models by maintaining levels of parkin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 2398-407. PMID 23392669 DOI: 10.1523/JNEUROSCI.2292-12.2013  0.92
2013 Tang G, Gutierrez Rios P, Kuo SH, Akman HO, Rosoklija G, Tanji K, Dwork A, Schon EA, Dimauro S, Goldman J, Sulzer D. Mitochondrial abnormalities in temporal lobe of autistic brain. Neurobiology of Disease. 54: 349-61. PMID 23333625 DOI: 10.1016/j.nbd.2013.01.006  0.92
2013 Surmeier DJ, Sulzer D. The pathology roadmap in Parkinson disease. Prion. 7: 85-91. PMID 23324593 DOI: 10.4161/pri.23582  0.92
2013 Rodriguez PC, Pereira DB, Borgkvist A, Wong MY, Barnard C, Sonders MS, Zhang H, Sames D, Sulzer D. Fluorescent dopamine tracer resolves individual dopaminergic synapses and their activity in the brain. Proceedings of the National Academy of Sciences of the United States of America. 110: 870-5. PMID 23277566 DOI: 10.1073/pnas.1213569110  0.92
2013 Sulzer D, Surmeier DJ. Neuronal vulnerability, pathogenesis, and Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 28: 41-50. PMID 22791686 DOI: 10.1002/mds.25095  0.92
2013 Mosharov E, Kanter E, Wu M, Cuervo AM, Sulzer D. Role of Multiple Factors in Susceptibility of Neurons in Parkinson's Disease Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 138. DOI: 10.1016/B978-0-12-800044-1.00122-7  0.92
2013 Cebrián C, Zucca FA, Zecca L, Loike JD, Sulzer D. A Role For Neuronal MHC-I Display in Parkinson's Disease? Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 136. DOI: 10.1016/B978-0-12-800044-1.00120-3  0.92
2012 Kuo SH, Tang G, Ma K, Babij R, Cortes E, Vonsattel JP, Faust PL, Sulzer D, Louis ED. Macroautophagy abnormality in essential tremor. Plos One. 7: e53040. PMID 23300858 DOI: 10.1371/journal.pone.0053040  0.92
2012 Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Sulzer D, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490  0.36
2012 Torres CA, Sulzer D. Macroautophagy can press a brake on presynaptic neurotransmission. Autophagy. 8: 1540-1. PMID 22767262 DOI: 10.4161/auto.21330  0.92
2012 Anzalone A, Lizardi-Ortiz JE, Ramos M, De Mei C, Hopf FW, Iaccarino C, Halbout B, Jacobsen J, Kinoshita C, Welter M, Caron MG, Bonci A, Sulzer D, Borrelli E. Dual control of dopamine synthesis and release by presynaptic and postsynaptic dopamine D2 receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9023-34. PMID 22745501 DOI: 10.1523/JNEUROSCI.0918-12.2012  0.92
2012 Zhang H, Sulzer D. Regulation of striatal dopamine release by presynaptic auto- and heteroreceptors. Basal Ganglia. 2: 5-13. PMID 22712055 DOI: 10.1016/j.baga.2011.11.004  0.92
2012 Pereira DB, Sulzer D. Mechanisms of dopamine quantal size regulation. Frontiers in Bioscience (Landmark Edition). 17: 2740-67. PMID 22652810 DOI: 10.2741/4083  0.92
2012 Hernandez D, Torres CA, Setlik W, Cebrián C, Mosharov EV, Tang G, Cheng HC, Kholodilov N, Yarygina O, Burke RE, Gershon M, Sulzer D. Regulation of presynaptic neurotransmission by macroautophagy. Neuron. 74: 277-84. PMID 22542182 DOI: 10.1016/j.neuron.2012.02.020  0.92
2011 Koga H, Martinez-Vicente M, Arias E, Kaushik S, Sulzer D, Cuervo AM. Constitutive upregulation of chaperone-mediated autophagy in Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 18492-505. PMID 22171050 DOI: 10.1523/JNEUROSCI.3219-11.2011  0.92
2011 Wong MY, Sulzer D, Bamford NS. Imaging presynaptic exocytosis in corticostriatal slices. Methods in Molecular Biology (Clifton, N.J.). 793: 363-76. PMID 21913113 DOI: 10.1007/978-1-61779-328-8_24  0.92
2011 Borgkvist A, Mrejeru A, Sulzer D. Multiple personalities in the ventral tegmental area. Neuron. 70: 803-5. PMID 21658574 DOI: 10.1016/j.neuron.2011.05.024  0.92
2011 Sulzer D. How addictive drugs disrupt presynaptic dopamine neurotransmission. Neuron. 69: 628-49. PMID 21338876 DOI: 10.1016/j.neuron.2011.02.010  0.92
2011 Zhang W, Phillips K, Wielgus AR, Liu J, Albertini A, Zucca FA, Faust R, Qian SY, Miller DS, Chignell CF, Wilson B, Jackson-Lewis V, Przedborski S, Joset D, Loike J, ... ... Sulzer D, et al. Neuromelanin activates microglia and induces degeneration of dopaminergic neurons: implications for progression of Parkinson's disease. Neurotoxicity Research. 19: 63-72. PMID 19957214 DOI: 10.1007/s12640-009-9140-z  0.92
2011 Lyon GJ, Abi-Dargham A, Moore H, Lieberman JA, Javitch JA, Sulzer D. Presynaptic regulation of dopamine transmission in schizophrenia. Schizophrenia Bulletin. 37: 108-17. PMID 19525353 DOI: 10.1093/schbul/sbp010  0.92
2010 Bendor J, Lizardi-Ortiz JE, Westphalen RI, Brandstetter M, Hemmings HC, Sulzer D, Flajolet M, Greengard P. AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release. The Embo Journal. 29: 2813-26. PMID 20664521 DOI: 10.1038/emboj.2010.154  0.92
2010 Lee M, Gubernator NG, Sulzer D, Sames D. Development of pH-responsive fluorescent false neurotransmitters. Journal of the American Chemical Society. 132: 8828-30. PMID 20540519 DOI: 10.1021/ja101740k  0.92
2010 Martinez-Vicente M, Talloczy Z, Wong E, Tang G, Koga H, Kaushik S, de Vries R, Arias E, Harris S, Sulzer D, Cuervo AM. Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease. Nature Neuroscience. 13: 567-76. PMID 20383138 DOI: 10.1038/nn.2528  0.92
2010 Hnasko TS, Chuhma N, Zhang H, Goh GY, Sulzer D, Palmiter RD, Rayport S, Edwards RH. Vesicular glutamate transport promotes dopamine storage and glutamate corelease in vivo. Neuron. 65: 643-56. PMID 20223200 DOI: 10.1016/j.neuron.2010.02.012  0.92
2010 Sulzer D. Clues to how alpha-synuclein damages neurons in Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 25: S27-31. PMID 20187229 DOI: 10.1002/mds.22639  0.92
2009 Schmitz Y, Luccarelli J, Kim M, Wang M, Sulzer D. Glutamate controls growth rate and branching of dopaminergic axons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 11973-81. PMID 19776283 DOI: 10.1523/JNEUROSCI.2927-09.2009  0.92
2009 Zhang H, Gubernator NG, Yue M, Staal RG, Mosharov EV, Pereira D, Balsanek V, Vadola PA, Mukherjee B, Edwards RH, Sulzer D, Sames D. Dopamine release at individual presynaptic terminals visualized with FFNs. Journal of Visualized Experiments : Jove. PMID 19721412 DOI: 10.3791/1562  0.92
2009 Gubernator NG, Zhang H, Staal RG, Mosharov EV, Pereira DB, Yue M, Balsanek V, Vadola PA, Mukherjee B, Edwards RH, Sulzer D, Sames D. Fluorescent false neurotransmitters visualize dopamine release from individual presynaptic terminals. Science (New York, N.Y.). 324: 1441-4. PMID 19423778 DOI: 10.1126/science.1172278  0.92
2009 Mosharov EV, Larsen KE, Kanter E, Phillips KA, Wilson K, Schmitz Y, Krantz DE, Kobayashi K, Edwards RH, Sulzer D. Interplay between cytosolic dopamine, calcium, and alpha-synuclein causes selective death of substantia nigra neurons. Neuron. 62: 218-29. PMID 19409267 DOI: 10.1016/j.neuron.2009.01.033  0.92
2009 Lu XH, Fleming SM, Meurers B, Ackerson LC, Mortazavi F, Lo V, Hernandez D, Sulzer D, Jackson GR, Maidment NT, Chesselet MF, Yang XW. Bacterial artificial chromosome transgenic mice expressing a truncated mutant parkin exhibit age-dependent hypokinetic motor deficits, dopaminergic neuron degeneration, and accumulation of proteinase K-resistant alpha-synuclein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1962-76. PMID 19228951 DOI: 10.1523/JNEUROSCI.5351-08.2009  0.92
2009 Mosharov EV, Sulzer D. Convergence of multiple hits that could underlie Parkinson's disease Future Neurology. 4: 525-529. DOI: 10.2217/fnl.09.40  0.92
2008 Markov D, Mosharov EV, Setlik W, Gershon MD, Sulzer D. Secretory vesicle rebound hyperacidification and increased quantal size resulting from prolonged methamphetamine exposure. Journal of Neurochemistry. 107: 1709-21. PMID 19014382 DOI: 10.1111/j.1471-4159.2008.05737.x  0.92
2008 Bamford NS, Zhang H, Joyce JA, Scarlis CA, Hanan W, Wu NP, André VM, Cohen R, Cepeda C, Levine MS, Harleton E, Sulzer D. Repeated exposure to methamphetamine causes long-lasting presynaptic corticostriatal depression that is renormalized with drug readministration. Neuron. 58: 89-103. PMID 18400166 DOI: 10.1016/j.neuron.2008.01.033  0.92
2008 Sulzer D, Mosharov E, Talloczy Z, Zucca FA, Simon JD, Zecca L. Neuronal pigmented autophagic vacuoles: lipofuscin, neuromelanin, and ceroid as macroautophagic responses during aging and disease. Journal of Neurochemistry. 106: 24-36. PMID 18384642 DOI: 10.1111/j.1471-4159.2008.05385.x  0.92
2008 Tallóczy Z, Martinez J, Joset D, Ray Y, Gácser A, Toussi S, Mizushima N, Nosanchuk JD, Nosanchuk J, Goldstein H, Loike J, Sulzer D, Santambrogio L. Methamphetamine inhibits antigen processing, presentation, and phagocytosis. Plos Pathogens. 4: e28. PMID 18282092 DOI: 10.1371/journal.ppat.0040028  0.92
2008 Tang G, Yue Z, Talloczy Z, Hagemann T, Cho W, Messing A, Sulzer DL, Goldman JE. Autophagy induced by Alexander disease-mutant GFAP accumulation is regulated by p38/MAPK and mTOR signaling pathways. Human Molecular Genetics. 17: 1540-55. PMID 18276609 DOI: 10.1093/hmg/ddn042  0.92
2008 Staal RG, Hananiya A, Sulzer D. PKC theta activity maintains normal quantal size in chromaffin cells. Journal of Neurochemistry. 105: 1635-41. PMID 18248621 DOI: 10.1111/j.1471-4159.2008.05264.x  0.92
2008 Martinez-Vicente M, Talloczy Z, Kaushik S, Massey AC, Mazzulli J, Mosharov EV, Hodara R, Fredenburg R, Wu DC, Follenzi A, Dauer W, Przedborski S, Ischiropoulos H, Lansbury PT, Sulzer D, et al. Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy. The Journal of Clinical Investigation. 118: 777-88. PMID 18172548 DOI: 10.1172/JCI32806  0.92
2008 Sulzer D, Trudeau LE, Rayport S. Postnatally Derived Ventral Midbrain Dopamine Neuron Cultures as a Model System for Studying Neurotoxicity and Parkinson's Disease Parkinson's Disease. 491-504. DOI: 10.1016/B978-0-12-374028-1.00037-3  0.92
2007 Sulzer D, Schmitz Y. Parkinson's disease: return of an old prime suspect. Neuron. 55: 8-10. PMID 17610813 DOI: 10.1016/j.neuron.2007.06.023  0.92
2007 Sulzer D. Multiple hit hypotheses for dopamine neuron loss in Parkinson's disease. Trends in Neurosciences. 30: 244-50. PMID 17418429 DOI: 10.1016/j.tins.2007.03.009  0.92
2006 Larsen KE, Schmitz Y, Troyer MD, Mosharov E, Dietrich P, Quazi AZ, Savalle M, Nemani V, Chaudhry FA, Edwards RH, Stefanis L, Sulzer D. Alpha-synuclein overexpression in PC12 and chromaffin cells impairs catecholamine release by interfering with a late step in exocytosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 11915-22. PMID 17108165 DOI: 10.1523/JNEUROSCI.3821-06.2006  0.92
2006 Larsen KE, Benn SC, Ay I, Chian RJ, Celia SA, Remington MP, Bejarano M, Liu M, Ross J, Carmillo P, Sah D, Phillips KA, Sulzer D, Pepinsky RB, Fishman PS, et al. A glial cell line-derived neurotrophic factor (GDNF):tetanus toxin fragment C protein conjugate improves delivery of GDNF to spinal cord motor neurons in mice. Brain Research. 1120: 1-12. PMID 17020749 DOI: 10.1016/j.brainres.2006.08.079  0.92
2006 Mosharov EV, Staal RG, Bové J, Prou D, Hananiya A, Markov D, Poulsen N, Larsen KE, Moore CM, Troyer MD, Edwards RH, Przedborski S, Sulzer D. Alpha-synuclein overexpression increases cytosolic catecholamine concentration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 9304-11. PMID 16957086 DOI: 10.1523/JNEUROSCI.0519-06.2006  0.92
2005 Li H, Waites CL, Staal RG, Dobryy Y, Park J, Sulzer DL, Edwards RH. Sorting of vesicular monoamine transporter 2 to the regulated secretory pathway confers the somatodendritic exocytosis of monoamines. Neuron. 48: 619-33. PMID 16301178 DOI: 10.1016/j.neuron.2005.09.033  0.32
2005 Paterlini M, Zakharenko SS, Lai WS, Qin J, Zhang H, Mukai J, Westphal KG, Olivier B, Sulzer D, Pavlidis P, Siegelbaum SA, Karayiorgou M, Gogos JA. Transcriptional and behavioral interaction between 22q11.2 orthologs modulates schizophrenia-related phenotypes in mice. Nature Neuroscience. 8: 1586-94. PMID 16234811 DOI: 10.1038/nn1562  0.92
2005 Mosharov EV, Sulzer D. Analysis of exocytotic events recorded by amperometry. Nature Methods. 2: 651-8. PMID 16118635 DOI: 10.1038/nmeth782  0.92
2005 Son JH, Kawamata H, Yoo MS, Kim DJ, Lee YK, Kim S, Dawson TM, Zhang H, Sulzer D, Yang L, Beal MF, Degiorgio LA, Chun HS, Baker H, Peng C. Neurotoxicity and behavioral deficits associated with Septin 5 accumulation in dopaminergic neurons. Journal of Neurochemistry. 94: 1040-53. PMID 16092945 DOI: 10.1111/j.1471-4159.2005.03257.x  0.92
2005 Giraudo CG, Hu C, You D, Slovic AM, Mosharov EV, Sulzer D, Melia TJ, Rothman JE. SNAREs can promote complete fusion and hemifusion as alternative outcomes. The Journal of Cell Biology. 170: 249-60. PMID 16027221 DOI: 10.1083/jcb.200501093  0.44
2005 Sulzer D, Sonders MS, Poulsen NW, Galli A. Mechanisms of neurotransmitter release by amphetamines: a review. Progress in Neurobiology. 75: 406-33. PMID 15955613 DOI: 10.1016/j.pneurobio.2005.04.003  0.92
2005 Sulzer D, Edwards RH. Antidepressants and the monoamine masquerade. Neuron. 46: 1-2. PMID 15820686 DOI: 10.1016/j.neuron.2005.03.013  0.32
2005 Sulzer D. The complex regulation of dopamine output: A review of current themes Clinical Neuroscience Research. 5: 117-121. DOI: 10.1016/j.cnr.2005.08.007  0.92
2004 Fahn S, Sulzer D. Neurodegeneration and neuroprotection in Parkinson disease. Neurorx : the Journal of the American Society For Experimental Neurotherapeutics. 1: 139-54. PMID 15717014 DOI: 10.1602/neurorx.1.1.139  0.92
2004 Zucca FA, Giaveri G, Gallorini M, Albertini A, Toscani M, Pezzoli G, Lucius R, Wilms H, Sulzer D, Ito S, Wakamatsu K, Zecca L. The neuromelanin of human substantia nigra: physiological and pathogenic aspects. Pigment Cell Research / Sponsored by the European Society For Pigment Cell Research and the International Pigment Cell Society. 17: 610-7. PMID 15541018 DOI: 10.1111/j.1600-0749.2004.00201.x  0.92
2004 Cuervo AM, Stefanis L, Fredenburg R, Lansbury PT, Sulzer D. Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy. Science (New York, N.Y.). 305: 1292-5. PMID 15333840 DOI: 10.1126/science.1101738  0.92
2004 Bamford NS, Zhang H, Schmitz Y, Wu NP, Cepeda C, Levine MS, Schmauss C, Zakharenko SS, Zablow L, Sulzer D. Heterosynaptic dopamine neurotransmission selects sets of corticostriatal terminals. Neuron. 42: 653-63. PMID 15157425 DOI: 10.1016/S0896-6273(04)00265-X  0.92
2004 Zhang H, Sulzer D. Frequency-dependent modulation of dopamine release by nicotine. Nature Neuroscience. 7: 581-2. PMID 15146187 DOI: 10.1038/nn1243  0.92
2004 Kholodilov N, Yarygina O, Oo TF, Zhang H, Sulzer D, Dauer W, Burke RE. Regulation of the development of mesencephalic dopaminergic systems by the selective expression of glial cell line-derived neurotrophic factor in their targets. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3136-46. PMID 15044553 DOI: 10.1523/JNEUROSCI.4506-03.2004  0.92
2004 Staal RG, Mosharov EV, Sulzer D. Dopamine neurons release transmitter via a flickering fusion pore. Nature Neuroscience. 7: 341-6. PMID 14990933 DOI: 10.1038/nn1205  0.92
2004 Chuhma N, Zhang H, Masson J, Zhuang X, Sulzer D, Hen R, Rayport S. Dopamine neurons mediate a fast excitatory signal via their glutamatergic synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 972-81. PMID 14749442 DOI: 10.1523/JNEUROSCI.4317-03.2004  0.48
2003 Zhang H, Sulzer D. Glutamate spillover in the striatum depresses dopaminergic transmission by activating group I metabotropic glutamate receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 10585-92. PMID 14627643  0.92
2003 Venton BJ, Zhang H, Garris PA, Phillips PE, Sulzer D, Wightman RM. Real-time decoding of dopamine concentration changes in the caudate-putamen during tonic and phasic firing. Journal of Neurochemistry. 87: 1284-95. PMID 14622108 DOI: 10.1046/j.1471-4159.2003.02109.x  0.92
2003 Zecca L, Zucca FA, Wilms H, Sulzer D. Neuromelanin of the substantia nigra: a neuronal black hole with protective and toxic characteristics. Trends in Neurosciences. 26: 578-80. PMID 14585596 DOI: 10.1016/j.tins.2003.08.009  0.92
2003 Schmitz Y, Benoit-Marand M, Gonon F, Sulzer D. Presynaptic regulation of dopaminergic neurotransmission. Journal of Neurochemistry. 87: 273-89. PMID 14511105 DOI: 10.1046/j.1471-4159.2003.02050.x  0.92
2003 Zecca L, Zucca FA, Costi P, Tampellini D, Gatti A, Gerlach M, Riederer P, Fariello RG, Ito S, Gallorini M, Sulzer D. The neuromelanin of human substantia nigra: structure, synthesis and molecular behaviour. Journal of Neural Transmission. Supplementum. 145-55. PMID 12946053  0.92
2003 Mosharov EV, Gong LW, Khanna B, Sulzer D, Lindau M. Intracellular patch electrochemistry: regulation of cytosolic catecholamines in chromaffin cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 5835-45. PMID 12843288  0.92
2003 Davila V, Yan Z, Craciun LC, Logothetis D, Sulzer D. D3 dopamine autoreceptors do not activate G-protein-gated inwardly rectifying potassium channel currents in substantia nigra dopamine neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 5693-7. PMID 12843272  0.92
2003 Sulzer D, Galli A. Dopamine transport currents are promoted from curiosity to physiology. Trends in Neurosciences. 26: 173-6. PMID 12689764 DOI: 10.1016/S0166-2236(03)00063-8  0.92
2002 Staal RG, Mosharov E, Sulzer D. Calmodulin inhibitors block quantal catecholamine release and increase acidification of neurosecretory granules in rat adrenal chromaffin cells. Annals of the New York Academy of Sciences. 971: 269-72. PMID 12438131  0.44
2002 Fremeau RT, Burman J, Qureshi T, Tran CH, Proctor J, Johnson J, Zhang H, Sulzer D, Copenhagen DR, Storm-Mathisen J, Reimer RJ, Chaudhry FA, Edwards RH. The identification of vesicular glutamate transporter 3 suggests novel modes of signaling by glutamate. Proceedings of the National Academy of Sciences of the United States of America. 99: 14488-93. PMID 12388773 DOI: 10.1073/pnas.222546799  0.92
2002 Larsen KE, Fon EA, Hastings TG, Edwards RH, Sulzer D. Methamphetamine-induced degeneration of dopaminergic neurons involves autophagy and upregulation of dopamine synthesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 8951-60. PMID 12388602  0.92
2002 Dauer W, Kholodilov N, Vila M, Trillat AC, Goodchild R, Larsen KE, Staal R, Tieu K, Schmitz Y, Yuan CA, Rocha M, Jackson-Lewis V, Hersch S, Sulzer D, Przedborski S, et al. Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP. Proceedings of the National Academy of Sciences of the United States of America. 99: 14524-9. PMID 12376616 DOI: 10.1073/pnas.172514599  0.4
2002 Schmitz Y, Schmauss C, Sulzer D. Altered dopamine release and uptake kinetics in mice lacking D2 receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 8002-9. PMID 12223553  0.92
2002 Larsen KE, Sulzer D. Autophagy in neurons: a review. Histology and Histopathology. 17: 897-908. PMID 12168801  0.92
2002 Pothos EN, Mosharov E, Liu KP, Setlik W, Haburcak M, Baldini G, Gershon MD, Tamir H, Sulzer D. Stimulation-dependent regulation of the pH, volume and quantal size of bovine and rodent secretory vesicles. The Journal of Physiology. 542: 453-76. PMID 12122145 DOI: 10.1113/jphysiol.2002.018630  0.92
2002 Zecca L, Tampellini D, Gatti A, Crippa R, Eisner M, Sulzer D, Ito S, Fariello R, Gallorini M. The neuromelanin of human substantia nigra and its interaction with metals. Journal of Neural Transmission (Vienna, Austria : 1996). 109: 663-72. PMID 12111458 DOI: 10.1007/s007020200055  0.92
2002 Przedborski S, Jackson-Lewis V, Sulzer D, Naini A, Romero N, Chen C, Arias J. Transgenic superoxide dismutase overproducer: murine. Methods in Enzymology. 349: 180-90. PMID 11912908 DOI: 10.1016/S0076-6879(02)49334-2  0.92
2002 Zecca L, Fariello R, Riederer P, Sulzer D, Gatti A, Tampellini D. The absolute concentration of nigral neuromelanin, assayed by a new sensitive method, increases throughout the life and is dramatically decreased in Parkinson's disease. Febs Letters. 510: 216-20. PMID 11801257 DOI: 10.1016/S0014-5793(01)03269-0  0.92
2001 Stefanis L, Larsen KE, Rideout HJ, Sulzer D, Greene LA. Expression of A53T mutant but not wild-type alpha-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 9549-60. PMID 11739566  0.92
2001 Sulzer D. alpha-synuclein and cytosolic dopamine: stabilizing a bad situation. Nature Medicine. 7: 1280-2. PMID 11726961 DOI: 10.1038/nm1201-1280  0.32
2001 Zecca L, Tampellini D, Gerlach M, Riederer P, Fariello RG, Sulzer D. Substantia nigra neuromelanin: structure, synthesis, and molecular behaviour. Molecular Pathology : Mp. 54: 414-8. PMID 11724917  0.92
2001 Petersén A, Hansson O, Puschban Z, Sapp E, Romero N, Castilho RF, Sulzer D, Rice M, DiFiglia M, Przedborski S, Brundin P. Mice transgenic for exon 1 of the Huntington's disease gene display reduced striatal sensitivity to neurotoxicity induced by dopamine and 6-hydroxydopamine. The European Journal of Neuroscience. 14: 1425-35. PMID 11722604 DOI: 10.1046/j.0953-816X.2001.01765.x  0.92
2001 Petersén A A, Larsen KE, Behr GG, Romero N, Przedborski S, Brundin P, Sulzer D. Brain-derived neurotrophic factor inhibits apoptosis and dopamine-induced free radical production in striatal neurons but does not prevent cell death. Brain Research Bulletin. 56: 331-5. PMID 11719268 DOI: 10.1016/S0361-9230(01)00580-9  0.92
2001 Rideout HJ, Larsen KE, Sulzer D, Stefanis L. Proteasomal inhibition leads to formation of ubiquitin/alpha-synuclein-immunoreactive inclusions in PC12 cells. Journal of Neurochemistry. 78: 899-908. PMID 11520910 DOI: 10.1046/j.1471-4159.2001.00474.x  0.92
2001 Schmitz Y, Lee CJ, Schmauss C, Gonon F, Sulzer D. Amphetamine distorts stimulation-dependent dopamine overflow: effects on D2 autoreceptors, transporters, and synaptic vesicle stores. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 5916-24. PMID 11487614  0.92
2001 Petersén A, Larsen KE, Behr GG, Romero N, Przedborski S, Brundin P, Sulzer D. Expanded CAG repeats in exon 1 of the Huntington's disease gene stimulate dopamine-mediated striatal neuron autophagy and degeneration. Human Molecular Genetics. 10: 1243-54. PMID 11406606  0.92
2000 Sulzer D, Zecca L. Intraneuronal dopamine-quinone synthesis: a review. Neurotoxicity Research. 1: 181-95. PMID 12835101  0.76
2000 Sulzer D, Bogulavsky J, Larsen KE, Behr G, Karatekin E, Kleinman MH, Turro N, Krantz D, Edwards RH, Greene LA, Zecca L. Neuromelanin biosynthesis is driven by excess cytosolic catecholamines not accumulated by synaptic vesicles. Proceedings of the National Academy of Sciences of the United States of America. 97: 11869-74. PMID 11050221 DOI: 10.1073/pnas.97.22.11869  0.92
2000 Sulzer D, Rayport S. Dale's principle and glutamate corelease from ventral midbrain dopamine neurons. Amino Acids. 19: 45-52. PMID 11026472 DOI: 10.1007/s007260070032  0.92
2000 Pothos EN, Larsen KE, Krantz DE, Liu Y, Haycock JW, Setlik W, Gershon MD, Edwards RH, Sulzer D. Synaptic vesicle transporter expression regulates vesicle phenotype and quantal size. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 7297-306. PMID 11007887  0.92
2000 Sulzer D, Pothos EN. Regulation of quantal size by presynaptic mechanisms. Reviews in the Neurosciences. 11: 159-212. PMID 10718152  0.92
2000 Abeliovich A, Schmitz Y, Fariñas I, Choi-Lundberg D, Ho WH, Castillo PE, Shinsky N, Verdugo JM, Armanini M, Ryan A, Hynes M, Phillips H, Sulzer D, Rosenthal A. Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system. Neuron. 25: 239-52. PMID 10707987  0.92
2000 Colliver TL, Hess EJ, Pothos EN, Sulzer D, Ewing AG. Quantitative and statistical analysis of the shape of amperometric spikes recorded from two populations of cells. Journal of Neurochemistry. 74: 1086-97. PMID 10693940  0.92
1999 Kholodilov NG, Neystat M, Oo TF, Lo SE, Larsen KE, Sulzer D, Burke RE. Increased expression of rat synuclein in the substantia nigra pars compacta identified by mRNA differential display in a model of developmental target injury. Journal of Neurochemistry. 73: 2586-99. PMID 10582622 DOI: 10.1046/j.1471-4159.1999.0732586.x  0.92
1998 Kozminski KD, Gutman DA, Davila V, Sulzer D, Ewing AG. Voltammetric and pharmacological characterization of dopamine release from single exocytotic events at rat pheochromocytoma (PC12) cells. Analytical Chemistry. 70: 3123-30. PMID 11013717 DOI: 10.1021/ac980129f  0.92
1998 Pothos EN, Sulzer D, Hoebel BG. Plasticity of quantal size in ventral midbrain dopamine neurons: possible implications for the neurochemistry of feeding and reward. Appetite. 31: 405. PMID 9920693 DOI: 10.1006/appe.1998.0210  0.92
1998 Anderson BB, Ewing AG, Sulzer D. Electrochemical detection of reverse transport from Planorbis giant dopamine neuron. Methods in Enzymology. 296: 675-89. PMID 9779482 DOI: 10.1016/S0076-6879(98)96048-7  0.92
1998 Mena MA, Davila V, Bogaluvsky J, Sulzer D. A synergistic neurotrophic response to l-dihydroxyphenylalanine and nerve growth factor. Molecular Pharmacology. 54: 678-86. PMID 9765511  0.92
1998 Burke RE, Antonelli M, Sulzer D. Glial cell line-derived neurotrophic growth factor inhibits apoptotic death of postnatal substantia nigra dopamine neurons in primary culture. Journal of Neurochemistry. 71: 517-25. PMID 9681441  0.92
1998 Pothos EN, Przedborski S, Davila V, Schmitz Y, Sulzer D. D2-Like dopamine autoreceptor activation reduces quantal size in PC12 cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 5575-85. PMID 9671649  0.92
1998 Sulzer D, Joyce MP, Lin L, Geldwert D, Haber SN, Hattori T, Rayport S. Dopamine neurons make glutamatergic synapses in vitro. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 4588-602. PMID 9614234  0.92
1998 Pothos EN, Davila V, Sulzer D. Presynaptic recording of quanta from midbrain dopamine neurons and modulation of the quantal size. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 4106-18. PMID 9592091  0.92
1998 Pothos EN, Sulzer D. Modulation of quantal dopamine release by psychostimulants. Advances in Pharmacology (San Diego, Calif.). 42: 198-202. PMID 9327878  0.92
1997 Fon EA, Pothos EN, Sun BC, Killeen N, Sulzer D, Edwards RH. Vesicular transport regulates monoamine storage and release but is not essential for amphetamine action. Neuron. 19: 1271-83. PMID 9427250 DOI: 10.1016/S0896-6273(00)80418-3  0.32
1997 Mena MA, Davila V, Sulzer D. Neurotrophic effects of L-DOPA in postnatal midbrain dopamine neuron/cortical astrocyte cocultures. Journal of Neurochemistry. 69: 1398-408. PMID 9326268  0.92
1997 Mena MA, Khan U, Togasaki DM, Sulzer D, Epstein CJ, Przedborski S. Effects of wild-type and mutated copper/zinc superoxide dismutase on neuronal survival and L-DOPA-induced toxicity in postnatal midbrain culture. Journal of Neurochemistry. 69: 21-33. PMID 9202290  0.92
1996 Przedborski S, Khan U, Kostic V, Carlson E, Epstein CJ, Sulzer D. Increased superoxide dismutase activity improves survival of cultured postnatal midbrain neurons. Journal of Neurochemistry. 67: 1383-92. PMID 8858919  0.92
1996 Sulzer D, St Remy C, Rayport S. Reserpine inhibits amphetamine action in ventral midbrain culture. Molecular Pharmacology. 49: 338-42. PMID 8632767  0.92
1996 Pothos E, Desmond M, Sulzer D. L-3,4-dihydroxyphenylalanine increases the quantal size of exocytotic dopamine release in vitro. Journal of Neurochemistry. 66: 629-36. PMID 8592133  0.92
1995 Sulzer D, Chen TK, Lau YY, Kristensen H, Rayport S, Ewing A. Amphetamine redistributes dopamine from synaptic vesicles to the cytosol and promotes reverse transport. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 4102-8. PMID 7751968  0.92
1995 Rayport S, Sulzer D. Visualization of antipsychotic drug binding to living mesolimbic neurons reveals D2 receptor, acidotropic, and lipophilic components. Journal of Neurochemistry. 65: 691-703. PMID 7616225  0.92
1994 Cubells JF, Rayport S, Rajendran G, Sulzer D. Methamphetamine neurotoxicity involves vacuolation of endocytic organelles and dopamine-dependent intracellular oxidative stress. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 2260-71. PMID 8158268  0.92
1993 Sulzer D, Maidment NT, Rayport S. Amphetamine and other weak bases act to promote reverse transport of dopamine in ventral midbrain neurons. Journal of Neurochemistry. 60: 527-35. PMID 8419534  0.92
1992 Sulzer D, Pothos E, Sung HM, Maidment NT, Hoebel BG, Rayport S. Weak base model of amphetamine action. Annals of the New York Academy of Sciences. 654: 525-8. PMID 1632618  0.92
1992 Rayport S, Sulzer D, Shi WX, Sawasdikosol S, Monaco J, Batson D, Rajendran G. Identified postnatal mesolimbic dopamine neurons in culture: morphology and electrophysiology. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 4264-80. PMID 1359033  0.92
1990 Sulzer D, Rayport S. Amphetamine and other psychostimulants reduce pH gradients in midbrain dopaminergic neurons and chromaffin granules: a mechanism of action. Neuron. 5: 797-808. PMID 2268433 DOI: 10.1016/0896-6273(90)90339-H  0.92
1990 Augenbraun E, Sulzer D, Rayport S, Setlik W, Holtzman E. Experiments on the use of DAMP to study retina and cultured neurons. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 38: 1927-31. PMID 1701464  0.92
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