Geoffrey D. Girnun, Ph.D. - Publications

Affiliations: 
2000 University of Iowa, Iowa City, IA 
Area:
radiation oncology

28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Bott AJ, Peng IC, Fan Y, Faubert B, Zhao L, Li J, Neidler S, Sun Y, Jaber N, Krokowski D, Lu W, Pan JA, Powers S, Rabinowitz J, Hatzoglou M, ... ... Girnun G, et al. Oncogenic Myc Induces Expression of Glutamine Synthetase through Promoter Demethylation. Cell Metabolism. PMID 26603296 DOI: 10.1016/j.cmet.2015.09.025  0.32
2015 Montal ED, Dewi R, Bhalla K, Ou L, Hwang BJ, Ropell AE, Gordon C, Liu WJ, DeBerardinis RJ, Sudderth J, Twaddel W, Boros LG, Shroyer KR, Duraisamy S, Drapkin R, ... ... Girnun GD, et al. PEPCK Coordinates the Regulation of Central Carbon Metabolism to Promote Cancer Cell Growth. Molecular Cell. PMID 26481663 DOI: 10.1016/j.molcel.2015.09.025  0.32
2015 Choe M, Brusgard JL, Chumsri S, Bhandary L, Zhao XF, Lu S, Goloubeva OG, Polster BM, Fiskum GM, Girnun GD, Kim MS, Passaniti A. The RUNX2 Transcription Factor Negatively Regulates SIRT6 Expression to Alter Glucose Metabolism in Breast Cancer Cells. Journal of Cellular Biochemistry. PMID 25808624 DOI: 10.1002/jcb.25171  0.32
2015 Choe M, Brusgard JL, Chumsri S, Bhandary L, Zhao XF, Lu S, Goloubeva OG, Polster BM, Fiskum GM, Girnun GD, Kim MS, Passaniti A. The RUNX2 Transcription Factor Negatively Regulates SIRT6 Expression to Alter Glucose Metabolism in Breast Cancer Cells Journal of Cellular Biochemistry. 116: v. DOI: 10.1002/jcb.25299  0.32
2014 Bhalla K, Liu WJ, Thompson K, Anders L, Devarakonda S, Dewi R, Buckley S, Hwang BJ, Polster B, Dorsey SG, Sun Y, Sicinski P, Girnun GD. Cyclin D1 represses gluconeogenesis via inhibition of the transcriptional coactivator PGC1α. Diabetes. 63: 3266-78. PMID 24947365 DOI: 10.2337/db13-1283  0.32
2013 Singh A, Happel C, Manna SK, Acquaah-Mensah G, Carrerero J, Kumar S, Nasipuri P, Krausz KW, Wakabayashi N, Dewi R, Boros LG, Gonzalez FJ, Gabrielson E, Wong KK, Girnun G, et al. Transcription factor NRF2 regulates miR-1 and miR-206 to drive tumorigenesis. The Journal of Clinical Investigation. 123: 2921-34. PMID 23921124 DOI: 10.1172/JCI66353  0.32
2013 Vazquez F, Lim JH, Chim H, Bhalla K, Girnun G, Pierce K, Clish CB, Granter SR, Widlund HR, Spiegelman BM, Puigserver P. PGC1α expression defines a subset of human melanoma tumors with increased mitochondrial capacity and resistance to oxidative stress. Cancer Cell. 23: 287-301. PMID 23416000 DOI: 10.1016/j.ccr.2012.11.020  0.32
2012 Clerc P, Carey GB, Mehrabian Z, Wei M, Hwang H, Girnun GD, Chen H, Martin SS, Polster BM. Rapid detection of an ABT-737-sensitive primed for death state in cells using microplate-based respirometry. Plos One. 7: e42487. PMID 22880001 DOI: 10.1371/journal.pone.0042487  0.32
2012 Bhalla K, Hwang BJ, Dewi RE, Twaddel W, Goloubeva OG, Wong KK, Saxena NK, Biswal S, Girnun GD. Metformin prevents liver tumorigenesis by inhibiting pathways driving hepatic lipogenesis. Cancer Prevention Research (Philadelphia, Pa.). 5: 544-52. PMID 22467080 DOI: 10.1158/1940-6207.CAPR-11-0228  0.32
2012 Girnun GD. The diverse role of the PPARγ coactivator 1 family of transcriptional coactivators in cancer. Seminars in Cell & Developmental Biology. 23: 381-8. PMID 22285815 DOI: 10.1016/j.semcdb.2012.01.007  0.32
2011 Bhalla K, Hwang BJ, Choi JH, Dewi R, Ou L, Mclenithan J, Twaddel W, Pozharski E, Stock J, Girnun GD. N-Acetylfarnesylcysteine is a novel class of peroxisome proliferator-activated receptor γ ligand with partial and full agonist activity in vitro and in vivo. The Journal of Biological Chemistry. 286: 41626-35. PMID 21979952 DOI: 10.1074/jbc.M111.257915  0.32
2011 Bhalla K, Hwang BJ, Dewi RE, Ou L, Twaddel W, Fang HB, Vafai SB, Vazquez F, Puigserver P, Boros L, Girnun GD. PGC1α promotes tumor growth by inducing gene expression programs supporting lipogenesis. Cancer Research. 71: 6888-98. PMID 21914785 DOI: 10.1158/0008-5472.CAN-11-1011  0.32
2010 Solazzo SA, Ahmed M, Schor-Bardach R, Yang W, Girnun GD, Rahmanuddin S, Levchenko T, Signoretti S, Spitz DR, Torchilin V, Goldberg SN. Liposomal doxorubicin increases radiofrequency ablation-induced tumor destruction by increasing cellular oxidative and nitrative stress and accelerating apoptotic pathways. Radiology. 255: 62-74. PMID 20160000 DOI: 10.1148/radiol.09091196  0.32
2009 Girnun G. PPARG: A New Independent Marker for Colorectal Cancer Survival Gastroenterology. 136: 1157-1160. PMID 19236969 DOI: 10.1053/j.gastro.2009.02.022  0.32
2008 Girnun GD, Howe LR, Manne S, Mao JT, Reid ME, Szabo E. Meeting report: Sixth Annual AACR International Conference on Frontiers in Cancer Prevention Research. Cancer Prevention Research (Philadelphia, Pa.). 1: 146-9. PMID 19138947 DOI: 10.1158/1940-6207.CAPR-08-0023  0.32
2008 Girnun GD, Chen L, Silvaggi J, Drapkin R, Chirieac LR, Padera RF, Upadhyay R, Vafai SB, Weissleder R, Mahmood U, Naseri E, Buckley S, Li D, Force J, McNamara K, et al. Regression of drug-resistant lung cancer by the combination of rosiglitazone and carboplatin. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 6478-86. PMID 18927287 DOI: 10.1158/1078-0432.CCR-08-1128  0.32
2008 Arany Z, Foo SY, Ma Y, Ruas JL, Bommi-Reddy A, Girnun G, Cooper M, Laznik D, Chinsomboon J, Rangwala SM, Baek KH, Rosenzweig A, Spiegelman BM. HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1alpha. Nature. 451: 1008-12. PMID 18288196 DOI: 10.1038/nature06613  0.32
2007 Girnun GD, Naseri E, Vafai SB, Qu L, Szwaya JD, Bronson R, Alberta JA, Spiegelman BM. Synergy between PPARgamma ligands and platinum-based drugs in cancer. Cancer Cell. 11: 395-406. PMID 17482130 DOI: 10.1016/j.ccr.2007.02.025  0.32
2005 Drori S, Girnun GD, Tou L, Szwaya JD, Mueller E, Xia K, Kia X, Shivdasani RA, Spiegelman BM. Hic-5 regulates an epithelial program mediated by PPARgamma. Genes & Development. 19: 362-75. PMID 15687259 DOI: 10.1101/gad.1240705  0.32
2003 Ahmed M, Monsky WE, Girnun G, Lukyanov A, D'Ippolito G, Kruskal JB, Stuart KE, Torchilin VP, Goldberg SN. Radiofrequency thermal ablation sharply increases intratumoral liposomal doxorubicin accumulation and tumor coagulation Cancer Research. 63: 6327-6333. PMID 14559820  0.32
2003 D'Ippolito G, Ahmed M, Girnun GD, Stuart KE, Kruskal JB, Halpern EF, Goldberg SN. Percutaneous tumor ablation: reduced tumor growth with combined radio-frequency ablation and liposomal doxorubicin in a rat breast tumor model. Radiology. 228: 112-8. PMID 12808127 DOI: 10.1148/radiol.2281020358  0.32
2003 Girnun GD, Spiegelman BM. PPARgamma ligands: taking Ppart in chemoprevention. Gastroenterology. 124: 564-7. PMID 12557160 DOI: 10.1053/gast.2003.50070  0.32
2003 Nambiar PR, Girnun G, Lillo NA, Guda K, Whiteley HE, Rosenberg DW. Preliminary analysis of azoxymethane induced colon tumors in inbred mice commonly used as transgenic/knockout progenitors. International Journal of Oncology. 22: 145-50. PMID 12469197  0.32
2002 Girnun GD, Domann FE, Moore SA, Robbins ME. Identification of a functional peroxisome proliferator-activated receptor response element in the rat catalase promoter. Molecular Endocrinology (Baltimore, Md.). 16: 2793-801. PMID 12456800 DOI: 10.1210/me.2002-0020  0.32
2002 Girnun GD, Smith WM, Drori S, Sarraf P, Mueller E, Eng C, Nambiar P, Rosenberg DW, Bronson RT, Edelmann W, Kucherlapati R, Gonzalez FJ, Spiegelman BM. APC-dependent suppression of colon carcinogenesis by PPARgamma. Proceedings of the National Academy of Sciences of the United States of America. 99: 13771-6. PMID 12370429 DOI: 10.1073/pnas.162480299  0.32
2002 Monsky WL, Kruskal JB, Lukyanov AN, Girnun GD, Ahmed M, Gazelle GS, Huertas JC, Stuart KE, Torchilin VP, Goldberg SN. Radio-frequency ablation increases intratumoral liposomal doxorubicin accumulation in a rat breast tumor model. Radiology. 224: 823-9. PMID 12202721 DOI: 10.1148/radiol.2243011421  0.32
2000 Preuss M, Girnun GD, Darby CJ, Khoo N, Spector AA, Robbins ME. Role of antioxidant enzyme expression in the selective cytotoxic response of glioma cells to gamma-linolenic acid supplementation. Free Radical Biology & Medicine. 28: 1143-56. PMID 10832077 DOI: 10.1016/S0891-5849(00)00210-0  0.32
1999 Girnun GD, Oberley LW, Moore SA, Robbins ME. Eicosapentaenoic acid alters manganese superoxide dismutase immunoreactive protein levels in normal but not malignant central nervous system derived cells. Advances in Experimental Medicine and Biology. 469: 647-53. PMID 10667394  0.32
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