| Year |
Citation |
Score |
| 2016 |
Lindenmaier LB, Philbrick KA, Branscum AJ, Kalra SP, Turner RT, Iwaniec UT. Hypothalamic Leptin Gene Therapy Reduces Bone Marrow Adiposity in ob/ob Mice Fed Regular and High-Fat Diets. Frontiers in Endocrinology. 7: 110. PMID 27579023 DOI: 10.3389/Fendo.2016.00110 |
0.305 |
|
| 2015 |
Turner RT, Dube M, Branscum AJ, Wong CP, Olson DA, Zhong X, Kweh MF, Larkin IV, Wronski TJ, Rosen CJ, Kalra SP, Iwaniec UT. Hypothalamic leptin gene therapy reduces body weight without accelerating age-related bone loss. The Journal of Endocrinology. 227: 129-41. PMID 26487675 DOI: 10.1530/Joe-15-0280 |
0.316 |
|
| 2011 |
Iwaniec UT, Boghossian S, Trevisiol CH, Wronski TJ, Turner RT, Kalra SP. Hypothalamic leptin gene therapy prevents weight gain without long-term detrimental effects on bone in growing and skeletally mature female rats. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 1506-16. PMID 21328617 DOI: 10.1002/jbmr.365 |
0.304 |
|
| 2010 |
Fetissov SO, Laviano A, Kalra S, Inui A. Update on ghrelin. International Journal of Peptides. 2010. PMID 20798849 DOI: 10.1155/2010/963501 |
0.382 |
|
| 2010 |
Kalra SP, Kalra PS. Neuroendocrine control of energy homeostasis: update on new insights. Progress in Brain Research. 181: 17-33. PMID 20478430 DOI: 10.1016/S0079-6123(08)81002-3 |
0.632 |
|
| 2009 |
Kalra SP. Central leptin gene therapy ameliorates diabetes type 1 and 2 through two independent hypothalamic relays; a benefit beyond weight and appetite regulation. Peptides. 30: 1957-63. PMID 19647774 DOI: 10.1016/j.peptides.2009.07.021 |
0.377 |
|
| 2009 |
Kalra SP, Dube MG, Iwaniec UT. Leptin increases osteoblast-specific osteocalcin release through a hypothalamic relay. Peptides. 30: 967-73. PMID 19428775 DOI: 10.1016/j.peptides.2009.01.020 |
0.398 |
|
| 2009 |
Kojima S, Asakawa A, Amitani H, Sakoguchi T, Ueno N, Inui A, Kalra SP. Central leptin gene therapy, a substitute for insulin therapy to ameliorate hyperglycemia and hyperphagia, and promote survival in insulin-deficient diabetic mice. Peptides. 30: 962-6. PMID 19428774 DOI: 10.1016/j.peptides.2009.01.007 |
0.347 |
|
| 2008 |
Kalra SP. Disruption in the leptin-NPY link underlies the pandemic of diabetes and metabolic syndrome: new therapeutic approaches. Nutrition (Burbank, Los Angeles County, Calif.). 24: 820-6. PMID 18725078 DOI: 10.1016/j.nut.2008.06.023 |
0.365 |
|
| 2008 |
Dube MG, Torto R, Kalra SP. Increased leptin expression selectively in the hypothalamus suppresses inflammatory markers CRP and IL-6 in leptin-deficient diabetic obese mice. Peptides. 29: 593-8. PMID 18325632 DOI: 10.1016/j.peptides.2008.01.001 |
0.4 |
|
| 2008 |
Kalra SP. Central leptin insufficiency syndrome: an interactive etiology for obesity, metabolic and neural diseases and for designing new therapeutic interventions. Peptides. 29: 127-38. PMID 18053615 DOI: 10.1016/j.peptides.2007.10.017 |
0.398 |
|
| 2007 |
Kalra SP. Global life-long health benefits of repression of hypothalamic NPY system by central leptin gene therapy. Current Topics in Medicinal Chemistry. 7: 1675-81. PMID 17979776 DOI: 10.2174/156802607782340993 |
0.457 |
|
| 2007 |
Dube MG, Kalra SP, Kalra PS. Low abundance of NPY in the hypothalamus can produce hyperphagia and obesity. Peptides. 28: 475-9. PMID 17222946 DOI: 10.1016/J.Peptides.2006.10.017 |
0.621 |
|
| 2007 |
Kalra SP, Kalra PS. To subjugate NPY is to improve the quality of life and live longer. Peptides. 28: 413-8. PMID 17215061 DOI: 10.1016/J.Peptides.2006.08.039 |
0.581 |
|
| 2007 |
Boghossian S, Ueno N, Dube MG, Kalra P, Kalra S. Leptin gene transfer in the hypothalamus enhances longevity in adult monogenic mutant mice in the absence of circulating leptin. Neurobiology of Aging. 28: 1594-604. PMID 17011078 DOI: 10.1016/J.Neurobiolaging.2006.08.010 |
0.661 |
|
| 2006 |
Torto R, Boghossian S, Dube MG, Kalra PS, Kalra SP. Central leptin gene therapy blocks ovariectomy-induced adiposity. Obesity (Silver Spring, Md.). 14: 1312-9. PMID 16988073 DOI: 10.1038/Oby.2006.149 |
0.676 |
|
| 2006 |
Boghossian S, Dube MG, Torto R, Kalra PS, Kalra SP. Hypothalamic clamp on insulin release by leptin-transgene expression. Peptides. 27: 3245-54. PMID 16962683 DOI: 10.1016/J.Peptides.2006.07.022 |
0.631 |
|
| 2006 |
Boghossian S, Lecklin A, Dube MG, Kalra PS, Kalra SP. Increased leptin expression in the dorsal vagal complex suppresses adiposity without affecting energy intake and metabolic hormones. Obesity (Silver Spring, Md.). 14: 1003-9. PMID 16861605 DOI: 10.1038/Oby.2006.115 |
0.692 |
|
| 2006 |
Dube MG, Kalra SP, Kalra PS. The hypothalamic paraventricular nucleus is not essential for orexigenic NPY or anorexigenic melanocortin action. Peptides. 27: 2239-48. PMID 16759748 DOI: 10.1016/J.Peptides.2006.04.005 |
0.544 |
|
| 2006 |
Ueno N, Inui A, Kalra PS, Kalra SP. Leptin transgene expression in the hypothalamus enforces euglycemia in diabetic, insulin-deficient nonobese Akita mice and leptin-deficient obese ob/ob mice. Peptides. 27: 2332-42. PMID 16621153 DOI: 10.1016/J.Peptides.2006.03.006 |
0.607 |
|
| 2006 |
Kalra SP, Kalra PS. Subjugation of hypothalamic NPY and cohorts with central leptin gene therapy alleviates dyslipidemia, insulin resistance, and obesity for life-time. Exs. 157-69. PMID 16383005 |
0.641 |
|
| 2006 |
Kennedy L, Bittel DC, Kibiryeva N, Kalra SP, Torto R, Butler MG. Circulating adiponectin levels, body composition and obesity-related variables in Prader-Willi syndrome: Comparison with obese subjects International Journal of Obesity. 30: 382-387. PMID 16231029 DOI: 10.1038/sj.ijo.0803115 |
0.345 |
|
| 2005 |
Kalra SP, Kalra PS. Gene-transfer technology: a preventive neurotherapy to curb obesity, ameliorate metabolic syndrome and extend life expectancy. Trends in Pharmacological Sciences. 26: 488-95. PMID 16125798 DOI: 10.1016/J.Tips.2005.08.008 |
0.599 |
|
| 2005 |
Boghossian S, Lecklin A, Torto R, Kalra PS, Kalra SP. Suppression of fat deposition for the life time with gene therapy. Peptides. 26: 1512-9. PMID 16042991 DOI: 10.1016/J.Peptides.2005.03.039 |
0.648 |
|
| 2005 |
Keen-Rhinehart E, Kalra SP, Kalra PS. AAV-mediated leptin receptor installation improves energy balance and the reproductive status of obese female Koletsky rats. Peptides. 26: 2567-78. PMID 16024137 DOI: 10.1016/J.Peptides.2005.05.027 |
0.675 |
|
| 2005 |
Otukonyong EE, Dube MG, Torto R, Kalra PS, Kalra SP. High-fat diet-induced ultradian leptin and insulin hypersecretion are absent in obesity-resistant rats. Obesity Research. 13: 991-9. PMID 15976141 DOI: 10.1038/Oby.2005.116 |
0.655 |
|
| 2005 |
Lecklin A, Dube MG, Torto RN, Kalra PS, Kalra SP. Perigestational suppression of weight gain with central leptin gene therapy results in lower weight F1 generation. Peptides. 26: 1176-87. PMID 15949636 DOI: 10.1016/J.Peptides.2005.01.021 |
0.629 |
|
| 2005 |
Otukonyong EE, Dube MG, Torto R, Kalra PS, Kalra SP. Central leptin differentially modulates ultradian secretory patterns of insulin, leptin and ghrelin independent of effects on food intake and body weight. Peptides. 26: 2559-66. PMID 15936848 DOI: 10.1016/J.Peptides.2005.04.015 |
0.699 |
|
| 2005 |
Kalra SP, Ueno N, Kalra PS. Stimulation of appetite by ghrelin is regulated by leptin restraint: peripheral and central sites of action. The Journal of Nutrition. 135: 1331-5. PMID 15867335 DOI: 10.1093/Jn/135.5.1331 |
0.644 |
|
| 2004 |
Kalra SP, Kalra PS. Overlapping and interactive pathways regulating appetite and craving. Journal of Addictive Diseases. 23: 5-21. PMID 15256341 DOI: 10.1300/J069V23N03_02 |
0.576 |
|
| 2004 |
Ueno N, Dube MG, Inui A, Kalra PS, Kalra SP. Leptin modulates orexigenic effects of ghrelin and attenuates adiponectin and insulin levels and selectively the dark-phase feeding as revealed by central leptin gene therapy. Endocrinology. 145: 4176-84. PMID 15155574 DOI: 10.1210/En.2004-0262 |
0.657 |
|
| 2004 |
Kalra SP, Kalra PS. NPY--an endearing journey in search of a neurochemical on/off switch for appetite, sex and reproduction. Peptides. 25: 465-71. PMID 15134867 DOI: 10.1016/J.Peptides.2004.03.001 |
0.521 |
|
| 2004 |
Keen Rhinehart E, Kalra SP, Kalra PS. Neuropeptidergic characterization of the leptin receptor mutated obese Koletsky rat. Regulatory Peptides. 119: 3-10. PMID 15093691 DOI: 10.1016/J.Regpep.2003.12.016 |
0.65 |
|
| 2004 |
Keen-Rhinehart E, Kalra SP, Kalra PS. Leptin-receptor gene transfer into the arcuate nucleus of female Fatty zucker rats using recombinant adeno-associated viral vectors stimulates the hypothalamo-pituitary-gonadal axis. Biology of Reproduction. 71: 266-72. PMID 14998906 DOI: 10.1095/Biolreprod.103.025858 |
0.59 |
|
| 2003 |
Bagnasco M, Dube MG, Katz A, Kalra PS, Kalra SP. Leptin expression in hypothalamic PVN reverses dietary obesity and hyperinsulinemia but stimulates ghrelin. Obesity Research. 11: 1463-70. PMID 14694210 DOI: 10.1038/Oby.2003.196 |
0.682 |
|
| 2003 |
Kalra SP, Kalra PS. Neuropeptide Y: a physiological orexigen modulated by the feedback action of ghrelin and leptin. Endocrine. 22: 49-56. PMID 14610298 DOI: 10.1385/Endo:22:1:49 |
0.626 |
|
| 2003 |
Kalra SP, Bagnasco M, Otukonyong EE, Dube MG, Kalra PS. Rhythmic, reciprocal ghrelin and leptin signaling: new insight in the development of obesity. Regulatory Peptides. 111: 1-11. PMID 12609743 DOI: 10.1016/S0167-0115(02)00305-1 |
0.648 |
|
| 2003 |
Kalra SP, Kalra PS. Keeping obesity and metabolic syndrome at bay with central leptin and cytokine gene therapy Current Medicinal Chemistry - Central Nervous System Agents. 3: 189-199. DOI: 10.2174/1568015033477703 |
0.582 |
|
| 2002 |
Kalra PS, Kalra SP. Obesity and metabolic syndrome: long-term benefits of central leptin gene therapy. Drugs of Today (Barcelona, Spain : 1998). 38: 745-57. PMID 12582458 DOI: 10.1358/Dot.2002.38.11.740201 |
0.694 |
|
| 2002 |
Beretta E, Dube MG, Kalra PS, Kalra SP. Long-term suppression of weight gain, adiposity, and serum insulin by central leptin gene therapy in prepubertal rats: effects on serum ghrelin and appetite-regulating genes. Pediatric Research. 52: 189-98. PMID 12149495 DOI: 10.1203/00006450-200208000-00010 |
0.661 |
|
| 2002 |
Beretta E, Dhillon H, Kalra PS, Kalra SP. Central LIF gene therapy suppresses food intake, body weight, serum leptin and insulin for extended periods. Peptides. 23: 975-84. PMID 12084530 DOI: 10.1016/S0196-9781(02)00021-9 |
0.657 |
|
| 2002 |
Dube MG, Beretta E, Dhillon H, Ueno N, Kalra PS, Kalra SP. Central leptin gene therapy blocks high-fat diet-induced weight gain, hyperleptinemia, and hyperinsulinemia: increase in serum ghrelin levels. Diabetes. 51: 1729-36. PMID 12031959 DOI: 10.2337/Diabetes.51.6.1729 |
0.642 |
|
| 2002 |
Bagnasco M, Kalra PS, Kalra SP. Plasma leptin levels are pulsatile in adult rats: effects of gonadectomy. Neuroendocrinology. 75: 257-63. PMID 11979056 DOI: 10.1159/000054717 |
0.57 |
|
| 2002 |
Bagnasco M, Kalra PS, Kalra SP. Ghrelin and leptin pulse discharge in fed and fasted rats. Endocrinology. 143: 726-9. PMID 11796530 DOI: 10.1210/Endo.143.2.8743 |
0.602 |
|
| 1999 |
Jain MR, Pu S, Kalra PS, Kalra SP. Evidence that Stimulation of Two Modalities of Pituitary Luteinizing Hormone Release in Ovarian Steroid-Primed Ovariectomized Rats May Involve Neuropeptide Y Y1 and Y4 Receptors1. Endocrinology. 140: 5171-5177. PMID 28204274 DOI: 10.1210/endo.140.11.7107 |
0.538 |
|
| 1999 |
Yokosuka M, Kalra PS, Kalra SP. Inhibition of Neuropeptide Y (NPY)-Induced Feeding and c-Fos Response in Magnocellular Paraventricular Nucleus by a NPY Receptor Antagonist: A Site of NPY Action1. Endocrinology. 140: 4494-4500. PMID 28200639 DOI: 10.1210/endo.140.10.7058 |
0.513 |
|
| 1999 |
Pu S, Jain MR, Horvath TL, Diano S, Kalra PS, Kalra SP. Interactions between Neuropeptide Y and γ -Aminobutyric Acid in Stimulation of Feeding: A Morphological and Pharmacological Analysis. Endocrinology. 140: 933-940. PMID 28200619 DOI: 10.1210/endo.140.2.6495 |
0.46 |
|
| 1998 |
Kaibara A, Moshyedi A, Auffenberg T, Abouhamze A, Copeland EM, Kalra S, Moldawer LL. Leptin produces anorexia and weight loss without inducing an acute phase response or protein wasting. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 274: R1518-R1525. PMID 29586666 DOI: 10.1152/ajpregu.1998.274.6.R1518 |
0.364 |
|
| 1998 |
Kaibara A, Moshyedi A, Auffenberg T, Abouhamze A, Copeland EM, Kalra S, Moldawer LL. Leptin produces anorexia and weight loss without inducing an acute phase response or protein wasting. The American Journal of Physiology. 274: R1518-25. PMID 9608004 DOI: 10.1152/Ajpregu.1998.274.6.R1518 |
0.461 |
|
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