Mark Tuszynski - Publications

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
plasticity, Alzheimer's, regeneration

221 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Biane JS, Takashima Y, Conner JM, Scanziani M, Tuszynski MH. Reorganization of Recurrent Layer 5 Corticospinal Networks Following Adult Motor Training. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30948479 DOI: 10.1523/JNEUROSCI.3442-17.2019  0.44
2019 Kumamaru H, Lu P, Rosenzweig ES, Kadoya K, Tuszynski MH. Regenerating Corticospinal Axons Innervate Phenotypically Appropriate Neurons within Neural Stem Cell Grafts. Cell Reports. 26: 2329-2339.e4. PMID 30811984 DOI: 10.1016/j.celrep.2019.01.099  0.48
2019 Lien BV, Tuszynski MH, Lu P. Astrocytes migrate from human neural stem cell grafts and functionally integrate into the injured rat spinal cord. Experimental Neurology. PMID 30653967 DOI: 10.1016/j.expneurol.2019.01.006  0.32
2019 Koffler J, Zhu W, Qu X, Platoshyn O, Dulin JN, Brock J, Graham L, Lu P, Sakamoto J, Marsala M, Chen S, Tuszynski MH. Biomimetic 3D-printed scaffolds for spinal cord injury repair. Nature Medicine. PMID 30643285 DOI: 10.1038/s41591-018-0296-z  0.56
2018 Kumamaru H, Lu P, Rosenzweig ES, Tuszynski MH. Activation of Intrinsic Growth State Enhances Host Axonal Regeneration into Neural Progenitor Cell Grafts. Stem Cell Reports. PMID 30197116 DOI: 10.1016/j.stemcr.2018.08.009  0.48
2018 Kumamaru H, Kadoya K, Adler AF, Takashima Y, Graham L, Coppola G, Tuszynski MH. Generation and post-injury integration of human spinal cord neural stem cells. Nature Methods. PMID 30082899 DOI: 10.1038/s41592-018-0074-3  0.56
2018 Poplawski GHD, Lie R, Hunt M, Kumamaru H, Kawaguchi R, Lu P, Schäfer MKE, Woodruff G, Robinson J, Canete P, Dulin JN, Geoffroy CG, Menzel L, Zheng B, Coppola G, ... Tuszynski MH, et al. Adult rat myelin enhances axonal outgrowth from neural stem cells. Science Translational Medicine. 10. PMID 29794059 DOI: 10.1126/scitranslmed.aal2563  0.32
2018 Rosenzweig ES, Brock JH, Lu P, Kumamaru H, Salegio EA, Kadoya K, Weber JL, Liang JJ, Moseanko R, Hawbecker S, Huie JR, Havton LA, Nout-Lomas YS, Ferguson AR, Beattie MS, ... ... Tuszynski MH, et al. Restorative effects of human neural stem cell grafts on the primate spinal cord. Nature Medicine. PMID 29480894 DOI: 10.1038/nm.4502  0.56
2018 Pawelec K, Koffler J, Shahriari D, Galvan AR, Tuszynski M, Sakamoto J. Microstructure and in vivo characterization of multi-channel nerve guidance scaffolds. Biomedical Materials (Bristol, England). PMID 29411711 DOI: 10.1088/1748-605X/aaad85  0.56
2018 Dulin JN, Adler AF, Kumamaru H, Poplawski GHD, Lee-Kubli C, Strobl H, Gibbs D, Kadoya K, Fawcett JW, Lu P, Tuszynski MH. Injured adult motor and sensory axons regenerate into appropriate organotypic domains of neural progenitor grafts. Nature Communications. 9: 84. PMID 29311559 DOI: 10.1038/s41467-017-02613-x  0.32
2017 Brock JH, Graham L, Staufenberg E, Im S, Tuszynski MH. Rodent Neural Progenitor Cells Support Functional Recovery After Cervical Spinal Cord Contusion. Journal of Neurotrauma. PMID 29279015 DOI: 10.1089/neu.2017.5244  0.56
2017 Lu P, Ceto S, Wang Y, Graham L, Wu D, Kumamaru H, Staufenberg E, Tuszynski MH. Prolonged human neural stem cell maturation supports recovery in injured rodent CNS. The Journal of Clinical Investigation. PMID 28825600 DOI: 10.1172/JCI92955  0.56
2017 Shahriari D, Shibayama M, Lynam D, Wolf K, Kubota G, Koffler J, Tuszynski M, Campana W, Sakamoto J. Peripheral Nerve Growth within a Hydrogel Microchannel Scaffold Supported by a Kink-Resistant Conduit. Journal of Biomedical Materials Research. Part A. PMID 28804998 DOI: 10.1002/jbm.a.36186  0.56
2017 Hunt M, Lu P, Tuszynski MH. Myelination of axons emerging from neural progenitor grafts after spinal cord injury. Experimental Neurology. PMID 28698030 DOI: 10.1016/j.expneurol.2017.07.005  0.32
2017 Lu P, Tuszynski MH. Introduction to Neuroscience Letters Special Issue: "Plasticity and Regeneration After Spinal Cord Injury". Neuroscience Letters. PMID 28432027 DOI: 10.1016/j.neulet.2017.04.029  0.32
2016 Gao M, Lu P, Lynam D, Bednark B, Campana WM, Sakamoto J, Tuszynski M. BDNF gene delivery within and beyond templated agarose multi-channel guidance scaffolds enhances peripheral nerve regeneration. Journal of Neural Engineering. 13: 066011. PMID 27762235 DOI: 10.1088/1741-2560/13/6/066011  0.32
2016 Cai DJ, Aharoni D, Shuman T, Shobe J, Biane J, Song W, Wei B, Veshkini M, La-Vu M, Lou J, Flores SE, Kim I, Sano Y, Zhou M, Baumgaertel K, ... ... Tuszynski M, et al. A shared neural ensemble links distinct contextual memories encoded close in time. Nature. 534: 115-8. PMID 27251287 DOI: 10.1038/nature17955  0.32
2016 Kadoya K, Lu P, Nguyen K, Lee-Kubli C, Kumamaru H, Yao L, Knackert J, Poplawski G, Dulin JN, Strobl H, Takashima Y, Biane J, Conner J, Zhang SC, Tuszynski MH. Spinal cord reconstitution with homologous neural grafts enables robust corticospinal regeneration. Nature Medicine. PMID 27019328 DOI: 10.1038/nm.4066  0.44
2016 Biane JS, Takashima Y, Scanziani M, Conner JM, Tuszynski MH. Thalamocortical Projections onto Behaviorally Relevant Neurons Exhibit Plasticity during Adult Motor Learning. Neuron. PMID 26948893 DOI: 10.1016/j.neuron.2016.02.001  1
2016 Wang L, Conner JM, Nagahara AH, Tuszynski MH. Rehabilitation drives enhancement of neuronal structure in functionally relevant neuronal subsets. Proceedings of the National Academy of Sciences of the United States of America. PMID 26903653 DOI: 10.1073/pnas.1514682113  1
2016 Chandran V, Coppola G, Nawabi H, Omura T, Versano R, Huebner EA, Zhang A, Costigan M, Yekkirala A, Barrett L, Blesch A, Michaelevski I, Davis-Turak J, Gao F, Langfelder P, ... ... Tuszynski M, et al. A Systems-Level Analysis of the Peripheral Nerve Intrinsic Axonal Growth Program. Neuron. PMID 26898779 DOI: 10.1016/j.neuron.2016.01.034  0.32
2016 Lee-Kubli CA, Ingves M, Henry KW, Shiao R, Collyer E, Tuszynski MH, Campana WM. Analysis of the behavioral, cellular and molecular characteristics of pain in severe rodent spinal cord injury. Experimental Neurology. PMID 26808661 DOI: 10.1016/j.expneurol.2016.01.009  0.32
2016 Salegio EA, Bresnahan JC, Sparrey CJ, Camisa W, Fischer J, Leasure J, Buckley J, Nout-Lomas YS, Rosenzweig ES, Moseanko R, Strand S, Hawbecker S, Lemoy MJ, Haefeli J, Ma X, ... ... Tuszynski MH, et al. A Unilateral Cervical Spinal Cord Contusion Injury Model in Non-Human Primates (Macaca mulatta). Journal of Neurotrauma. PMID 26788611 DOI: 10.1089/neu.2015.3956  0.32
2015 van Niekerk EA, Tuszynski MH, Lu P, Dulin JN. Molecular and Cellular Mechanisms of Axonal Regeneration After Spinal Cord Injury. Molecular & Cellular Proteomics : McP. PMID 26695766 DOI: 10.1074/mcp.R115.053751  0.32
2015 Shahriari D, Koffler J, Lynam DA, Tuszynski MH, Sakamoto JS. Characterizing the Degradation of Alginate Hydrogel for Use in Multilumen Scaffolds for Spinal Cord Repair. Journal of Biomedical Materials Research. Part A. PMID 26488452 DOI: 10.1002/jbm.a.35600  0.56
2015 Dulin JN, Antunes-Martins A, Chandran V, Costigan M, Lerch JK, Willis DE, Tuszynski MH. Transcriptomic Approaches to Neural Repair. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 13860-7. PMID 26468186 DOI: 10.1523/JNEUROSCI.2599-15.2015  0.32
2015 Brock JH, Graham L, Staufenberg E, Collyer E, Koffler Y, Tuszynski MH. Bone Marrow Stromal Cell Intraspinal Transplants Fail to Improve Motor Outcomes in a Severe Model of Spinal Cord Injury. Journal of Neurotrauma. PMID 26414795 DOI: 10.1089/neu.2015.4009  1
2015 Friedli L, Rosenzweig ES, Barraud Q, Schubert M, Dominici N, Awai L, Nielson JL, Musienko P, Nout-Lomas Y, Zhong H, Zdunowski S, Roy RR, Strand SC, van den Brand R, Havton LA, ... ... Tuszynski MH, et al. Pronounced species divergence in corticospinal tract reorganization and functional recovery after lateralized spinal cord injury favors primates. Science Translational Medicine. 7: 302ra134. PMID 26311729 DOI: 10.1126/scitranslmed.aac5811  0.32
2015 Tuszynski MH, Yang JH, Barba D, U HS, Bakay RA, Pay MM, Masliah E, Conner JM, Kobalka P, Roy S, Nagahara AH. Nerve Growth Factor Gene Therapy: Activation of Neuronal Responses in Alzheimer Disease. Jama Neurology. PMID 26302439 DOI: 10.1001/jamaneurol.2015.1807  1
2015 Biane JS, Scanziani M, Tuszynski MH, Conner JM. Motor cortex maturation is associated with reductions in recurrent connectivity among functional subpopulations and increases in intrinsic excitability. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 4719-28. PMID 25788688 DOI: 10.1523/JNEUROSCI.2792-14.2015  1
2015 Lynam DA, Shahriari D, Wolf KJ, Angart PA, Koffler J, Tuszynski MH, Chan C, Walton P, Sakamoto J. Brain derived neurotrophic factor release from layer-by-layer coated agarose nerve guidance scaffolds. Acta Biomaterialia. 18: 128-31. PMID 25712385 DOI: 10.1016/j.actbio.2015.02.014  1
2015 Ramanathan DS, Conner JM, Anilkumar AA, Tuszynski MH. Cholinergic systems are essential for late-stage maturation and refinement of motor cortical circuits. Journal of Neurophysiology. 113: 1585-97. PMID 25505106 DOI: 10.1152/jn.00408.2014  1
2014 Nielson JL, Haefeli J, Salegio EA, Liu AW, Guandique CF, Stück ED, Hawbecker S, Moseanko R, Strand SC, Zdunowski S, Brock JH, Roy RR, Rosenzweig ES, Nout-Lomas YS, Courtine G, ... ... Tuszynski MH, et al. Leveraging biomedical informatics for assessing plasticity and repair in primate spinal cord injury. Brain Research. PMID 25451131 DOI: 10.1016/j.brainres.2014.10.048  0.32
2014 Biane J, Conner JM, Tuszynski MH. Nerve growth factor is primarily produced by GABAergic neurons of the adult rat cortex. Frontiers in Cellular Neuroscience. 8: 220. PMID 25147503 DOI: 10.3389/fncel.2014.00220  1
2014 Lu P, Graham L, Wang Y, Wu D, Tuszynski M. Promotion of survival and differentiation of neural stem cells with fibrin and growth factor cocktails after severe spinal cord injury. Journal of Visualized Experiments : Jove. e50641. PMID 25145787 DOI: 10.3791/50641  1
2014 Lu P, Woodruff G, Wang Y, Graham L, Hunt M, Wu D, Boehle E, Ahmad R, Poplawski G, Brock J, Goldstein LS, Tuszynski MH. Long-distance axonal growth from human induced pluripotent stem cells after spinal cord injury. Neuron. 83: 789-96. PMID 25123310 DOI: 10.1016/j.neuron.2014.07.014  1
2014 Tuszynski MH, Wang Y, Graham L, McHale K, Gao M, Wu D, Brock J, Blesch A, Rosenzweig ES, Havton LA, Zheng B, Conner JM, Marsala M, Lu P. Neural stem cells in models of spinal cord injury. Experimental Neurology. 261: 494-500. PMID 25079369 DOI: 10.1016/j.expneurol.2014.07.011  1
2014 Nielson JL, Guandique CF, Liu AW, Burke DA, Lash AT, Moseanko R, Hawbecker S, Strand SC, Zdunowski S, Irvine KA, Brock JH, Nout-Lomas YS, Gensel JC, Anderson KD, Segal MR, ... ... Tuszynski MH, et al. Development of a database for translational spinal cord injury research. Journal of Neurotrauma. 31: 1789-99. PMID 25077610 DOI: 10.1089/neu.2014.3399  1
2014 Lu P, Kadoya K, Tuszynski MH. Axonal growth and connectivity from neural stem cell grafts in models of spinal cord injury. Current Opinion in Neurobiology. 27: 103-9. PMID 24709371 DOI: 10.1016/j.conb.2014.03.010  1
2014 Tuszynski MH, Wang Y, Graham L, Gao M, Wu D, Brock J, Blesch A, Rosenzweig ES, Havton LA, Zheng B, Conner JM, Marsala M, Lu P. Neural stem cell dissemination after grafting to CNS injury sites. Cell. 156: 388-9. PMID 24485445 DOI: 10.1016/j.cell.2014.01.016  1
2013 Ommaya AK, Adams KM, Allman RM, Collins EG, Cooper RA, Dixon CE, Fishman PS, Henry JA, Kardon R, Kerns RD, Kupersmith J, Lo A, Macko R, McArdle R, McGlinchey RE, ... ... Tuszynski MH, et al. Guest editorial: Opportunities in rehabilitation research. Journal of Rehabilitation Research and Development. 50: vii-xxxii. PMID 24203548 DOI: 10.1682/JRRD.2012.09.0167  1
2013 Nagahara AH, Mateling M, Kovacs I, Wang L, Eggert S, Rockenstein E, Koo EH, Masliah E, Tuszynski MH. Early BDNF treatment ameliorates cell loss in the entorhinal cortex of APP transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 15596-602. PMID 24068826 DOI: 10.1523/JNEUROSCI.5195-12.2013  1
2013 Do JL, Bonni A, Tuszynski MH. SnoN facilitates axonal regeneration after spinal cord injury. Plos One. 8: e71906. PMID 23936531 DOI: 10.1371/journal.pone.0071906  1
2013 Yoon C, Van Niekerk EA, Henry K, Ishikawa T, Orita S, Tuszynski MH, Campana WM. Low-density lipoprotein receptor-related protein 1 (LRP1)-dependent cell signaling promotes axonal regeneration. The Journal of Biological Chemistry. 288: 26557-68. PMID 23867460 DOI: 10.1074/jbc.M113.478552  1
2013 Gao M, Lu P, Bednark B, Lynam D, Conner JM, Sakamoto J, Tuszynski MH. Templated agarose scaffolds for the support of motor axon regeneration into sites of complete spinal cord transection. Biomaterials. 34: 1529-36. PMID 23182350 DOI: 10.1016/j.biomaterials.2012.10.070  1
2012 Yoon C, Tuszynski MH. Frontiers of spinal cord and spine repair: experimental approaches for repair of spinal cord injury. Advances in Experimental Medicine and Biology. 760: 1-15. PMID 23281510  1
2012 Blesch A, Fischer I, Tuszynski MH. Gene therapy, neurotrophic factors and spinal cord regeneration. Handbook of Clinical Neurology. 109: 563-74. PMID 23098737 DOI: 10.1016/B978-0-444-52137-8.00035-8  1
2012 Lu P, Wang Y, Graham L, McHale K, Gao M, Wu D, Brock J, Blesch A, Rosenzweig ES, Havton LA, Zheng B, Conner JM, Marsala M, Tuszynski MH. Long-distance growth and connectivity of neural stem cells after severe spinal cord injury. Cell. 150: 1264-73. PMID 22980985 DOI: 10.1016/j.cell.2012.08.020  1
2012 Yoon SO, Park DJ, Ryu JC, Ozer HG, Tep C, Shin YJ, Lim TH, Pastorino L, Kunwar AJ, Walton JC, Nagahara AH, Lu KP, Nelson RJ, Tuszynski MH, Huang K. JNK3 perpetuates metabolic stress induced by Aβ peptides. Neuron. 75: 824-37. PMID 22958823 DOI: 10.1016/j.neuron.2012.06.024  1
2012 Lu P, Blesch A, Graham L, Wang Y, Samara R, Banos K, Haringer V, Havton L, Weishaupt N, Bennett D, Fouad K, Tuszynski MH. Motor axonal regeneration after partial and complete spinal cord transection. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 8208-18. PMID 22699902 DOI: 10.1523/JNEUROSCI.0308-12.2012  1
2012 Tuszynski MH, Steward O. Concepts and methods for the study of axonal regeneration in the CNS. Neuron. 74: 777-91. PMID 22681683 DOI: 10.1016/j.neuron.2012.05.006  1
2012 Nout YS, Rosenzweig ES, Brock JH, Strand SC, Moseanko R, Hawbecker S, Zdunowski S, Nielson JL, Roy RR, Courtine G, Ferguson AR, Edgerton VR, Beattie MS, Bresnahan JC, Tuszynski MH. Animal models of neurologic disorders: a nonhuman primate model of spinal cord injury. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 9: 380-92. PMID 22427157 DOI: 10.1007/s13311-012-0114-0  1
2012 Nout YS, Ferguson AR, Strand SC, Moseanko R, Hawbecker S, Zdunowski S, Nielson JL, Roy RR, Zhong H, Rosenzweig ES, Brock JH, Courtine G, Edgerton VR, Tuszynski MH, Beattie MS, et al. Methods for functional assessment after C7 spinal cord hemisection in the rhesus monkey. Neurorehabilitation and Neural Repair. 26: 556-69. PMID 22331214 DOI: 10.1177/1545968311421934  1
2012 Blesch A, Lu P, Tsukada S, Alto LT, Roet K, Coppola G, Geschwind D, Tuszynski MH. Conditioning lesions before or after spinal cord injury recruit broad genetic mechanisms that sustain axonal regeneration: superiority to camp-mediated effects. Experimental Neurology. 235: 162-73. PMID 22227059 DOI: 10.1016/j.expneurol.2011.12.037  1
2012 Mehrotra S, Lynam D, Liu C, Shahriari D, Lee I, Tuszynski M, Sakamoto J, Chan C. Time controlled release of arabinofuranosylcytosine (Ara-C) from agarose hydrogels using layer-by-layer assembly: an in vitro study. Journal of Biomaterials Science. Polymer Edition. 23: 439-63. PMID 21294967 DOI: 10.1163/092050610X552221  1
2011 Hollis ER, Tuszynski MH. Neurotrophins: potential therapeutic tools for the treatment of spinal cord injury. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 8: 694-703. PMID 21904786 DOI: 10.1007/s13311-011-0074-9  1
2011 Nagahara AH, Tuszynski MH. Potential therapeutic uses of BDNF in neurological and psychiatric disorders. Nature Reviews. Drug Discovery. 10: 209-19. PMID 21358740 DOI: 10.1038/nrd3366  1
2011 Wang L, Conner JM, Rickert J, Tuszynski MH. Structural plasticity within highly specific neuronal populations identifies a unique parcellation of motor learning in the adult brain. Proceedings of the National Academy of Sciences of the United States of America. 108: 2545-50. PMID 21257908 DOI: 10.1073/pnas.1014335108  1
2011 Jindrich DL, Courtine G, Liu JJ, McKay HL, Moseanko R, Bernot TJ, Roy RR, Zhong H, Tuszynski MH, Reggie Edgerton V. Unconstrained three-dimensional reaching in rhesus monkeys. Experimental Brain Research. 209: 35-50. PMID 21170707 DOI: 10.1007/s00221-010-2514-x  1
2011 Merrill DA, Masliah E, Roberts JA, McKay H, Kordower JH, Mufson EJ, Tuszynski MH. Association of early experience with neurodegeneration in aged primates. Neurobiology of Aging. 32: 151-6. PMID 19321231 DOI: 10.1016/j.neurobiolaging.2009.01.014  1
2010 Rosenzweig ES, Courtine G, Jindrich DL, Brock JH, Ferguson AR, Strand SC, Nout YS, Roy RR, Miller DM, Beattie MS, Havton LA, Bresnahan JC, Edgerton VR, Tuszynski MH. Extensive spontaneous plasticity of corticospinal projections after primate spinal cord injury. Nature Neuroscience. 13: 1505-10. PMID 21076427 DOI: 10.1038/nn.2691  1
2010 Brock JH, Rosenzweig ES, Blesch A, Moseanko R, Havton LA, Edgerton VR, Tuszynski MH. Local and remote growth factor effects after primate spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 9728-37. PMID 20660255 DOI: 10.1523/JNEUROSCI.1924-10.2010  1
2010 Gros T, Sakamoto JS, Blesch A, Havton LA, Tuszynski MH. Regeneration of long-tract axons through sites of spinal cord injury using templated agarose scaffolds. Biomaterials. 31: 6719-29. PMID 20619785 DOI: 10.1016/j.biomaterials.2010.04.035  1
2010 Giger RJ, Hollis ER, Tuszynski MH. Guidance molecules in axon regeneration. Cold Spring Harbor Perspectives in Biology. 2: a001867. PMID 20519341 DOI: 10.1101/cshperspect.a001867  1
2010 Hollis ER, Jamshidi P, Lorenzana AO, Lee JK, Gray SJ, Samulski RJ, Zheng B, Tuszynski MH. Transient demyelination increases the efficiency of retrograde AAV transduction. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1496-500. PMID 20502445 DOI: 10.1038/mt.2010.97  1
2010 Mehrotra S, Lynam D, Maloney R, Pawelec KM, Tuszynski MH, Lee I, Chan C, Sakamoto J. Time Controlled Protein Release from Layer-by-Layer Assembled Multilayer Functionalized Agarose Hydrogels. Advanced Functional Materials. 20: 247-258. PMID 20200599 DOI: 10.1002/adfm.200901172  1
2010 Löw K, Blesch A, Herrmann J, Tuszynski MH. A dual promoter lentiviral vector for the in vivo evaluation of gene therapeutic approaches to axon regeneration after spinal cord injury. Gene Therapy. 17: 577-91. PMID 20200564 DOI: 10.1038/gt.2010.14  1
2010 Conner JM, Kulczycki M, Tuszynski MH. Unique contributions of distinct cholinergic projections to motor cortical plasticity and learning. Cerebral Cortex (New York, N.Y. : 1991). 20: 2739-48. PMID 20181623 DOI: 10.1093/cercor/bhq022  1
2010 Nagahara AH, Bernot T, Tuszynski MH. Age-related cognitive deficits in rhesus monkeys mirror human deficits on an automated test battery. Neurobiology of Aging. 31: 1020-31. PMID 18760505 DOI: 10.1016/j.neurobiolaging.2008.07.007  1
2010 Conner JM, Tuszynski MH. Neurotrophins: Physiology and Pharmacology Encyclopedia of Neuroscience. 1101-1106. DOI: 10.1016/B978-008045046-9.00520-9  1
2010 von dem Bussche M, Tuszynski MH. Growth Factors: Neuronal Atrophy Encyclopedia of Neuroscience. 987-992. DOI: 10.1016/B978-008045046-9.00143-1  1
2010 Blesch A, Tuszynski MH. Neurotrophic Factor Therapy: NGF, BDNF and NT-3 Encyclopedia of Neuroscience. 1093-1100. DOI: 10.1016/B978-008045046-9.00030-9  1
2009 Kadoya K, Tsukada S, Lu P, Coppola G, Geschwind D, Filbin MT, Blesch A, Tuszynski MH. Combined intrinsic and extrinsic neuronal mechanisms facilitate bridging axonal regeneration one year after spinal cord injury. Neuron. 64: 165-72. PMID 19874785 DOI: 10.1016/j.neuron.2009.09.016  1
2009 Conner JM, Franks KM, Titterness AK, Russell K, Merrill DA, Christie BR, Sejnowski TJ, Tuszynski MH. NGF is essential for hippocampal plasticity and learning. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 10883-9. PMID 19726646 DOI: 10.1523/JNEUROSCI.2594-09.2009  1
2009 Alto LT, Havton LA, Conner JM, Hollis ER, Blesch A, Tuszynski MH. Chemotropic guidance facilitates axonal regeneration and synapse formation after spinal cord injury. Nature Neuroscience. 12: 1106-13. PMID 19648914 DOI: 10.1038/nn.2365  1
2009 Ramanathan D, Tuszynski MH, Conner JM. The basal forebrain cholinergic system is required specifically for behaviorally mediated cortical map plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 5992-6000. PMID 19420265 DOI: 10.1523/JNEUROSCI.0230-09.2009  1
2009 Blight A, Curt A, Ditunno JF, Dobkin B, Ellaway P, Fawcett J, Fehlings M, Grossman RG, Lammertse DP, Privat A, Steeves J, Tuszynski M, Kalichman M, Guest JD. Position statement on the sale of unproven cellular therapies for spinal cord injury: the international campaign for cures of spinal cord injury paralysis. Spinal Cord. 47: 713-4. PMID 19417762 DOI: 10.1038/sc.2008.179  1
2009 Alfa RW, Tuszynski MH, Blesch A. A novel inducible tyrosine kinase receptor to regulate signal transduction and neurite outgrowth. Journal of Neuroscience Research. 87: 2624-31. PMID 19405107 DOI: 10.1002/jnr.22101  1
2009 Hollis ER, Jamshidi P, Löw K, Blesch A, Tuszynski MH. Induction of corticospinal regeneration by lentiviral trkB-induced Erk activation. Proceedings of the National Academy of Sciences of the United States of America. 106: 7215-20. PMID 19359495 DOI: 10.1073/pnas.0810624106  1
2009 Nagahara AH, Merrill DA, Coppola G, Tsukada S, Schroeder BE, Shaked GM, Wang L, Blesch A, Kim A, Conner JM, Rockenstein E, Chao MV, Koo EH, Geschwind D, Masliah E, ... ... Tuszynski MH, et al. Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease. Nature Medicine. 15: 331-7. PMID 19198615 DOI: 10.1038/nm.1912  1
2009 Rosenzweig ES, Brock JH, Culbertson MD, Lu P, Moseanko R, Edgerton VR, Havton LA, Tuszynski MH. Extensive spinal decussation and bilateral termination of cervical corticospinal projections in rhesus monkeys. The Journal of Comparative Neurology. 513: 151-63. PMID 19125408 DOI: 10.1002/cne.21940  1
2009 Nagahara AH, Bernot T, Moseanko R, Brignolo L, Blesch A, Conner JM, Ramirez A, Gasmi M, Tuszynski MH. Long-term reversal of cholinergic neuronal decline in aged non-human primates by lentiviral NGF gene delivery. Experimental Neurology. 215: 153-9. PMID 19013154 DOI: 10.1016/j.expneurol.2008.10.004  1
2009 Blesch A, Tuszynski MH. Spinal cord injury: plasticity, regeneration and the challenge of translational drug development. Trends in Neurosciences. 32: 41-7. PMID 18977039 DOI: 10.1016/j.tins.2008.09.008  1
2009 Hollis ER, Lu P, Blesch A, Tuszynski MH. IGF-I gene delivery promotes corticospinal neuronal survival but not regeneration after adult CNS injury. Experimental Neurology. 215: 53-9. PMID 18938163 DOI: 10.1016/j.expneurol.2008.09.014  1
2008 Herzog CD, Dass B, Gasmi M, Bakay R, Stansell JE, Tuszynski M, Bankiewicz K, Chen EY, Chu Y, Bishop K, Kordower JH, Bartus RT. Transgene expression, bioactivity, and safety of CERE-120 (AAV2-neurturin) following delivery to the monkey striatum. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1737-44. PMID 18728639 DOI: 10.1038/mt.2008.170  1
2008 Khachaturian ZS, Petersen RC, Gauthier S, Buckholtz N, Corey-Bloom JP, Evans B, Fillit H, Foster N, Greenberg B, Grundman M, Sano M, Simpkins J, Schneider LS, Weiner MW, Galasko D, ... ... Tuszynski MH, et al. A roadmap for the prevention of dementia: the inaugural Leon Thal Symposium. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 4: 156-63. PMID 18631960 DOI: 10.1016/j.jalz.2008.03.005  1
2008 Bishop KM, Hofer EK, Mehta A, Ramirez A, Sun L, Tuszynski M, Bartus RT. Therapeutic potential of CERE-110 (AAV2-NGF): targeted, stable, and sustained NGF delivery and trophic activity on rodent basal forebrain cholinergic neurons. Experimental Neurology. 211: 574-84. PMID 18439998 DOI: 10.1016/j.expneurol.2008.03.004  1
2008 Löw K, Culbertson M, Bradke F, Tessier-Lavigne M, Tuszynski MH. Netrin-1 is a novel myelin-associated inhibitor to axon growth. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1099-108. PMID 18234888 DOI: 10.1523/JNEUROSCI.4906-07.2008  1
2008 Hollis ER, Kadoya K, Hirsch M, Samulski RJ, Tuszynski MH. Efficient retrograde neuronal transduction utilizing self-complementary AAV1. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 296-301. PMID 18223548 DOI: 10.1038/sj.mt.6300367  1
2008 Lu P, Tuszynski MH. Growth factors and combinatorial therapies for CNS regeneration. Experimental Neurology. 209: 313-20. PMID 17927983 DOI: 10.1016/j.expneurol.2007.08.004  1
2008 Tuszynski MH, Lu P. Axonal plasticity and regeneration in the injured spinal cord Cns Regeneration. 319-335. DOI: 10.1016/B978-012373994-0.50015-4  1
2008 Blesch A, Tuszynski MH. Neurotrophic factors in alzheimer's disease Cns Regeneration. 201-221. DOI: 10.1016/B978-012373994-0.50010-5  1
2008 Kordower JH, Tuszynski MH. CNS Regeneration Cns Regeneration 1
2007 Bartus RT, Herzog CD, Bishop K, Ostrove JM, Tuszynski M, Kordower JH, Gasmi M. Issues regarding gene therapy products for Parkinson's disease: the development of CERE-120 (AAV-NTN) as one reference point. Parkinsonism & Related Disorders. 13: S469-77. PMID 18267286 DOI: 10.1016/S1353-8020(08)70052-X  1
2007 Alton E, Ferrari S, Griesenbach U, Aiuti A, Bachoud-Lévi AC, Blesch A, Brenner MK, Cattaneo F, Chiocca EA, Gao G, High KA, Leen AM, Lemoine NR, McNeish IA, Meneguzzi G, ... ... Tuszynski MH, et al. Progress and prospects: gene therapy clinical trials (part 2). Gene Therapy. 14: 1555-63. PMID 17984995 DOI: 10.1038/sj.gt.3303033  0.48
2007 Blesch A, Tuszynski MH. Transient growth factor delivery sustains regenerated axons after spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 10535-45. PMID 17898225 DOI: 10.1523/JNEUROSCI.1903-07.2007  1
2007 Tuszynski MH. Rebuilding the brain: resurgence of fetal grafting. Nature Neuroscience. 10: 1229-30. PMID 17893715 DOI: 10.1038/nn1007-1229  1
2007 Tuszynski MH. Nerve growth factor gene therapy in Alzheimer disease. Alzheimer Disease and Associated Disorders. 21: 179-89. PMID 17545746 DOI: 10.1097/WAD.0b013e318068d6d2  1
2007 Tuszynski MH. Nerve growth factor gene delivery: animal models to clinical trials. Developmental Neurobiology. 67: 1204-15. PMID 17514712 DOI: 10.1002/dneu.20510  1
2007 Herzog CD, Dass B, Holden JE, Stansell J, Gasmi M, Tuszynski MH, Bartus RT, Kordower JH. Striatal delivery of CERE-120, an AAV2 vector encoding human neurturin, enhances activity of the dopaminergic nigrostriatal system in aged monkeys. Movement Disorders : Official Journal of the Movement Disorder Society. 22: 1124-32. PMID 17443702 DOI: 10.1002/mds.21503  1
2007 Fawcett JW, Curt A, Steeves JD, Coleman WP, Tuszynski MH, Lammertse D, Bartlett PF, Blight AR, Dietz V, Ditunno J, Dobkin BH, Havton LA, Ellaway PH, Fehlings MG, Privat A, et al. Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP panel: spontaneous recovery after spinal cord injury and statistical power needed for therapeutic clinical trials. Spinal Cord. 45: 190-205. PMID 17179973 DOI: 10.1038/sj.sc.3102007  1
2007 Steeves JD, Lammertse D, Curt A, Fawcett JW, Tuszynski MH, Ditunno JF, Ellaway PH, Fehlings MG, Guest JD, Kleitman N, Bartlett PF, Blight AR, Dietz V, Dobkin BH, Grossman R, et al. Guidelines for the conduct of clinical trials for spinal cord injury (SCI) as developed by the ICCP panel: clinical trial outcome measures. Spinal Cord. 45: 206-21. PMID 17179972 DOI: 10.1038/sj.sc.3102008  1
2007 Tuszynski MH, Steeves JD, Fawcett JW, Lammertse D, Kalichman M, Rask C, Curt A, Ditunno JF, Fehlings MG, Guest JD, Ellaway PH, Kleitman N, Bartlett PF, Blight AR, Dietz V, et al. Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP Panel: clinical trial inclusion/exclusion criteria and ethics. Spinal Cord. 45: 222-31. PMID 17179971 DOI: 10.1038/sj.sc.3102009  1
2007 Lammertse D, Tuszynski MH, Steeves JD, Curt A, Fawcett JW, Rask C, Ditunno JF, Fehlings MG, Guest JD, Ellaway PH, Kleitman N, Blight AR, Dobkin BH, Grossman R, Katoh H, et al. Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP panel: clinical trial design. Spinal Cord. 45: 232-42. PMID 17179970 DOI: 10.1038/sj.sc.3102010  1
2007 Lu P, Jones LL, Tuszynski MH. Axon regeneration through scars and into sites of chronic spinal cord injury. Experimental Neurology. 203: 8-21. PMID 17014846 DOI: 10.1016/j.expneurol.2006.07.030  1
2007 Nagahara AH, Tuszynski MH. Growth factors in alzheimer's disease Alzheimer's Disease: Advances in Genetics, Molecular and Cellular Biology. 257-277. DOI: 10.1007/978-0-387-35135-3_15  1
2006 Stokols S, Sakamoto J, Breckon C, Holt T, Weiss J, Tuszynski MH. Templated agarose scaffolds support linear axonal regeneration. Tissue Engineering. 12: 2777-87. PMID 17518647 DOI: 10.1089/ten.2006.12.2777  1
2006 Tuszynski M. Challenges to the report of Nogo antibody effects in primates. Nature Medicine. 12: 1231-2; author reply. PMID 17088880 DOI: 10.1038/nm1106-1231c  1
2006 Lu P, Yang H, Culbertson M, Graham L, Roskams AJ, Tuszynski MH. Olfactory ensheathing cells do not exhibit unique migratory or axonal growth-promoting properties after spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 11120-30. PMID 17065452 DOI: 10.1523/JNEUROSCI.3264-06.2006  1
2006 Blurton-Jones M, Tuszynski MH. Estradiol-induced modulation of estrogen receptor-beta and GABA within the adult neocortex: a potential transsynaptic mechanism for estrogen modulation of BDNF. The Journal of Comparative Neurology. 499: 603-12. PMID 17029253 DOI: 10.1002/cne.21122  1
2006 Taylor L, Jones L, Tuszynski MH, Blesch A. Neurotrophin-3 gradients established by lentiviral gene delivery promote short-distance axonal bridging beyond cellular grafts in the injured spinal cord. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 9713-21. PMID 16988042 DOI: 10.1523/JNEUROSCI.0734-06.2006  1
2006 Ramanathan D, Conner JM, Tuszynski MH. A form of motor cortical plasticity that correlates with recovery of function after brain injury. Proceedings of the National Academy of Sciences of the United States of America. 103: 11370-5. PMID 16837575 DOI: 10.1073/pnas.0601065103  1
2006 Blight AR, Tuszynski MH. Clinical trials in spinal cord injury. Journal of Neurotrauma. 23: 586-93. PMID 16629639 DOI: 10.1089/neu.2006.23.586  1
2006 Yang H, Lu P, McKay HM, Bernot T, Keirstead H, Steward O, Gage FH, Edgerton VR, Tuszynski MH. Endogenous neurogenesis replaces oligodendrocytes and astrocytes after primate spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 2157-66. PMID 16495442 DOI: 10.1523/JNEUROSCI.4070-05.2005  1
2006 Stokols S, Tuszynski MH. Freeze-dried agarose scaffolds with uniaxial channels stimulate and guide linear axonal growth following spinal cord injury. Biomaterials. 27: 443-51. PMID 16099032 DOI: 10.1016/j.biomaterials.2005.06.039  1
2005 Tuszynski MH. New strategies for CNS repair. Ernst Schering Research Foundation Workshop. 1-10. PMID 16315605  1
2005 Courtine G, Roy RR, Raven J, Hodgson J, McKay H, Yang H, Zhong H, Tuszynski MH, Edgerton VR. Performance of locomotion and foot grasping following a unilateral thoracic corticospinal tract lesion in monkeys (Macaca mulatta). Brain : a Journal of Neurology. 128: 2338-58. PMID 16049043 DOI: 10.1093/brain/awh604  1
2005 Blesch A, Conner J, Pfeifer A, Gasmi M, Ramirez A, Britton W, Alfa R, Verma I, Tuszynski MH. Regulated lentiviral NGF gene transfer controls rescue of medial septal cholinergic neurons. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 916-25. PMID 15922962 DOI: 10.1016/j.ymthe.2005.01.007  1
2005 Lu P, Tuszynski MH. Can bone marrow-derived stem cells differentiate into functional neurons? Experimental Neurology. 193: 273-8. PMID 15869931 DOI: 10.1016/j.expneurol.2005.01.031  1
2005 Tuszynski MH, Thal L, Pay M, Salmon DP, U HS, Bakay R, Patel P, Blesch A, Vahlsing HL, Ho G, Tong G, Potkin SG, Fallon J, Hansen L, Mufson EJ, et al. A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease. Nature Medicine. 11: 551-5. PMID 15852017 DOI: 10.1038/nm1239  1
2005 Conner JM, Chiba AA, Tuszynski MH. The basal forebrain cholinergic system is essential for cortical plasticity and functional recovery following brain injury. Neuron. 46: 173-9. PMID 15848797 DOI: 10.1016/j.neuron.2005.03.003  1
2005 Anderson DK, Beattie M, Blesch A, Bresnahan J, Bunge M, Dietrich D, Dietz V, Dobkin B, Fawcett J, Fehlings M, Fischer I, Grossman R, Guest J, Hagg T, Hall ED, ... ... Tuszynski MH, et al. Recommended guidelines for studies of human subjects with spinal cord injury. Spinal Cord. 43: 453-8. PMID 15824756 DOI: 10.1038/sj.sc.3101746  1
2005 Lu P, Jones LL, Tuszynski MH. BDNF-expressing marrow stromal cells support extensive axonal growth at sites of spinal cord injury. Experimental Neurology. 191: 344-60. PMID 15649491 DOI: 10.1016/j.expneurol.2004.09.018  1
2005 Courtine G, Roy RR, Hodgson J, McKay H, Raven J, Zhong H, Yang H, Tuszynski MH, Edgerton VR. Kinematic and EMG determinants in quadrupedal locomotion of a non-human primate (Rhesus). Journal of Neurophysiology. 93: 3127-45. PMID 15647397 DOI: 10.1152/jn.01073.2004  1
2005 Tuszynski MH. Prospects for Gene Therapy for Central Nervous System Disease From Neuroscience to Neurology. 267-283. DOI: 10.1016/B978-012738903-5/50016-3  1
2004 Steeves J, Fawcett J, Tuszynski M. Report of international clinical trials workshop on spinal cord injury February 20-21, 2004, Vancouver, Canada. Spinal Cord. 42: 591-7. PMID 15303119 DOI: 10.1038/sj.sc.3101669  1
2004 Imitola J, Park KI, Teng YD, Nisim S, Lachyankar M, Ourednik J, Mueller FJ, Yiou R, Atala A, Sidman RL, Tuszynski M, Khoury SJ, Snyder EY. Stem cells: cross-talk and developmental programs. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 359: 823-37. PMID 15293810 DOI: 10.1098/rstb.2004.1474  1
2004 Lu P, Yang H, Jones LL, Filbin MT, Tuszynski MH. Combinatorial therapy with neurotrophins and cAMP promotes axonal regeneration beyond sites of spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 6402-9. PMID 15254096 DOI: 10.1523/JNEUROSCI.1492-04.2004  1
2004 Blesch A, Tuszynski MH. Gene therapy and cell transplantation for Alzheimer's disease and spinal cord injury. Yonsei Medical Journal. 45: 28-31. PMID 15250047  1
2004 Lu P, Blesch A, Tuszynski MH. Induction of bone marrow stromal cells to neurons: differentiation, transdifferentiation, or artifact? Journal of Neuroscience Research. 77: 174-91. PMID 15211585 DOI: 10.1002/jnr.20148  1
2004 Stokols S, Tuszynski MH. The fabrication and characterization of linearly oriented nerve guidance scaffolds for spinal cord injury. Biomaterials. 25: 5839-46. PMID 15172496 DOI: 10.1016/j.biomaterials.2004.01.041  1
2004 Nagahara A, Tuszynski MH. The ageless question--what accounts for age-related cognitive decline? Science of Aging Knowledge Environment : Sage Ke. 2004: pe20. PMID 15141075 DOI: 10.1126/sageke.2004.19.pe20  1
2004 Smith DE, Rapp PR, McKay HM, Roberts JA, Tuszynski MH. Memory impairment in aged primates is associated with focal death of cortical neurons and atrophy of subcortical neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4373-81. PMID 15128851 DOI: 10.1523/JNEUROSCI.4289-03.2004  1
2004 Lacroix S, Havton LA, McKay H, Yang H, Brant A, Roberts J, Tuszynski MH. Bilateral corticospinal projections arise from each motor cortex in the macaque monkey: a quantitative study. The Journal of Comparative Neurology. 473: 147-61. PMID 15101086 DOI: 10.1002/cne.20051  1
2004 Blesch A, Tuszynski MH. Nucleus hears axon's pain. Nature Medicine. 10: 236-7. PMID 14991043 DOI: 10.1038/nm0304-236  1
2004 Tuszynski MH, Blesch A. Nerve growth factor: from animal models of cholinergic neuronal degeneration to gene therapy in Alzheimer's disease. Progress in Brain Research. 146: 441-9. PMID 14699979  1
2004 Blurton-Jones M, Kuan PN, Tuszynski MH. Anatomical evidence for transsynaptic influences of estrogen on brain-derived neurotrophic factor expression. The Journal of Comparative Neurology. 468: 347-60. PMID 14681930 DOI: 10.1002/cne.10989  1
2003 Tobias CA, Shumsky JS, Shibata M, Tuszynski MH, Fischer I, Tessler A, Murray M. Delayed grafting of BDNF and NT-3 producing fibroblasts into the injured spinal cord stimulates sprouting, partially rescues axotomized red nucleus neurons from loss and atrophy, and provides limited regeneration. Experimental Neurology. 184: 97-113. PMID 14637084 DOI: 10.1016/S0014-4886(03)00394-7  1
2003 Blesch A, Tuszynski MH. Cellular GDNF delivery promotes growth of motor and dorsal column sensory axons after partial and complete spinal cord transections and induces remyelination. The Journal of Comparative Neurology. 467: 403-17. PMID 14608602 DOI: 10.1002/cne.10934  1
2003 Jones LL, Sajed D, Tuszynski MH. Axonal regeneration through regions of chondroitin sulfate proteoglycan deposition after spinal cord injury: a balance of permissiveness and inhibition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9276-88. PMID 14561854  1
2003 Jones LL, Margolis RU, Tuszynski MH. The chondroitin sulfate proteoglycans neurocan, brevican, phosphacan, and versican are differentially regulated following spinal cord injury. Experimental Neurology. 182: 399-411. PMID 12895450 DOI: 10.1016/S0014-4886(03)00087-6  1
2003 Tuszynski MH. Gene therapy for neurological disease. Expert Opinion On Biological Therapy. 3: 815-28. PMID 12880381 DOI: 10.1517/14712598.3.5.815  1
2003 Conner JM, Culberson A, Packowski C, Chiba AA, Tuszynski MH. Lesions of the Basal forebrain cholinergic system impair task acquisition and abolish cortical plasticity associated with motor skill learning. Neuron. 38: 819-29. PMID 12797965 DOI: 10.1016/S0896-6273(03)00288-5  1
2003 Lu P, Jones LL, Snyder EY, Tuszynski MH. Neural stem cells constitutively secrete neurotrophic factors and promote extensive host axonal growth after spinal cord injury. Experimental Neurology. 181: 115-29. PMID 12781986 DOI: 10.1016/S0014-4886(03)00037-2  1
2003 Tuszynski MH, Grill R, Jones LL, Brant A, Blesch A, Löw K, Lacroix S, Lu P. NT-3 gene delivery elicits growth of chronically injured corticospinal axons and modestly improves functional deficits after chronic scar resection. Experimental Neurology. 181: 47-56. PMID 12710933 DOI: 10.1016/S0014-4886(02)00055-9  1
2003 Merrill DA, Karim R, Darraq M, Chiba AA, Tuszynski MH. Hippocampal cell genesis does not correlate with spatial learning ability in aged rats. The Journal of Comparative Neurology. 459: 201-7. PMID 12640670 DOI: 10.1002/cne.10616  1
2002 Merrill DA, Blesch A, Tuszynski MH. Therapeutic potential of nervous system growth factors for neurodegenerative disease. Expert Review of Neurotherapeutics. 2: 89-96. PMID 19811018 DOI: 10.1586/14737175.2.1.89  1
2002 Tuszynski MH. Growth-factor gene therapy for neurodegenerative disorders. The Lancet. Neurology. 1: 51-7. PMID 12849545 DOI: 10.1016/S1474-4422(02)00006-6  1
2002 Lacroix S, Chang L, Rose-John S, Tuszynski MH. Delivery of hyper-interleukin-6 to the injured spinal cord increases neutrophil and macrophage infiltration and inhibits axonal growth. The Journal of Comparative Neurology. 454: 213-28. PMID 12442313 DOI: 10.1002/cne.10407  1
2002 Blesch A, Tuszynski MH. Spontaneous and neurotrophin-induced axonal plasticity after spinal cord injury. Progress in Brain Research. 137: 415-23. PMID 12440384 DOI: 10.1016/S0079-6123(02)37033-X  1
2002 Tuszynski MH, Conner J, Blesch A, Smith D, Merrill DA, Vahlsing HL. New strategies in neural repair. Progress in Brain Research. 138: 401-9. PMID 12432780 DOI: 10.1016/S0079-6123(02)38089-0  1
2002 Blurton-Jones M, Tuszynski MH. Estrogen receptor-beta colocalizes extensively with parvalbumin-labeled inhibitory neurons in the cortex, amygdala, basal forebrain, and hippocampal formation of intact and ovariectomized adult rats. The Journal of Comparative Neurology. 452: 276-87. PMID 12353223 DOI: 10.1002/cne.10393  1
2002 Tuszynski MH, Thal L, U HS, Pay MM, Blesch A, Conner J, Vahlsing HL. Nerve growth factor gene therapy for Alzheimer's disease. Journal of Molecular Neuroscience : Mn. 19: 207. PMID 12212782  1
2002 Tuszynski MH, Grill R, Jones LL, McKay HM, Blesch A. Spontaneous and augmented growth of axons in the primate spinal cord: effects of local injury and nerve growth factor-secreting cell grafts. The Journal of Comparative Neurology. 449: 88-101. PMID 12115695 DOI: 10.1002/cne.10266  1
2002 Jones LL, Tuszynski MH. Spinal cord injury elicits expression of keratan sulfate proteoglycans by macrophages, reactive microglia, and oligodendrocyte progenitors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 4611-24. PMID 12040068  1
2002 Blesch A, Lu P, Tuszynski MH. Neurotrophic factors, gene therapy, and neural stem cells for spinal cord repair. Brain Research Bulletin. 57: 833-8. PMID 12031281 DOI: 10.1016/B978-012373994-0.50006-3  1
2002 Jones LL, Yamaguchi Y, Stallcup WB, Tuszynski MH. NG2 is a major chondroitin sulfate proteoglycan produced after spinal cord injury and is expressed by macrophages and oligodendrocyte progenitors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 2792-803. PMID 11923444  1
2002 Weidner N, Tuszynski MH. Spontaneous plasticity in the injured spinal cord-implications for repair strategies. Molecular Psychiatry. 7: 9-11. PMID 11803438 DOI: 10.1038/sj.mp.4001983  1
2001 Merrill DA, Chiba AA, Tuszynski MH. Conservation of neuronal number and size in the entorhinal cortex of behaviorally characterized aged rats. The Journal of Comparative Neurology. 438: 445-56. PMID 11559900 DOI: 10.1002/cne.1327  1
2001 Jones LL, Tuszynski MH. Chronic intrathecal infusions after spinal cord injury cause scarring and compression. Microscopy Research and Technique. 54: 317-24. PMID 11514988 DOI: 10.1002/jemt.1144  1
2001 Lu P, Blesch A, Tuszynski MH. Neurotrophism without neurotropism: BDNF promotes survival but not growth of lesioned corticospinal neurons. The Journal of Comparative Neurology. 436: 456-70. PMID 11447589 DOI: 10.1002/cne.1080  1
2001 Blesch A, Tuszynski MH. GDNF gene delivery to injured adult CNS motor neurons promotes axonal growth, expression of the trophic neuropeptide CGRP, and cellular protection. The Journal of Comparative Neurology. 436: 399-410. PMID 11447585 DOI: 10.1002/cne.1076  1
2001 Blesch A, Conner JM, Tuszynski MH. Modulation of neuronal survival and axonal growth in vivo by tetracycline-regulated neurotrophin expression. Gene Therapy. 8: 954-60. PMID 11426336 DOI: 10.1038/sj.gt.3301480  1
2001 Jones LL, Oudega M, Bunge MB, Tuszynski MH. Neurotrophic factors, cellular bridges and gene therapy for spinal cord injury. The Journal of Physiology. 533: 83-9. PMID 11351016 DOI: 10.1111/j.1469-7793.2001.0083b.x  1
2001 Blurton-Jones M, Tuszynski MH. Reactive astrocytes express estrogen receptors in the injured primate brain. The Journal of Comparative Neurology. 433: 115-23. PMID 11283953 DOI: 10.1002/cne.1129  1
2001 Weidner N, Ner A, Salimi N, Tuszynski MH. Spontaneous corticospinal axonal plasticity and functional recovery after adult central nervous system injury. Proceedings of the National Academy of Sciences of the United States of America. 98: 3513-8. PMID 11248109 DOI: 10.1073/pnas.051626798  1
2001 Conner JM, Darracq MA, Roberts J, Tuszynski MH. Nontropic actions of neurotrophins: subcortical nerve growth factor gene delivery reverses age-related degeneration of primate cortical cholinergic innervation. Proceedings of the National Academy of Sciences of the United States of America. 98: 1941-6. PMID 11172055 DOI: 10.1073/pnas.98.4.1941  1
2000 Lacroix S, Tuszynski MH. Neurotrophic factors and gene therapy in spinal cord injury. Neurorehabilitation and Neural Repair. 14: 265-75. PMID 11402877  1
2000 Tuszynski MH. Intraparenchymal NGF infusions rescue degenerating cholinergic neurons. Cell Transplantation. 9: 629-36. PMID 11144960  1
2000 Bowes M, Tuszynski MH, Conner J, Zivin JA. Continuous intrathecal fluid infusions elevate nerve growth factor levels and prevent functional deficits after spinal cord ischemia. Brain Research. 883: 178-83. PMID 11074046 DOI: 10.1016/S0006-8993(00)02779-7  1
2000 Merrill DA, Roberts JA, Tuszynski MH. Conservation of neuron number and size in entorhinal cortex layers II, III, and V/VI of aged primates. The Journal of Comparative Neurology. 422: 396-401. PMID 10861515 DOI: 10.1002/1096-9861(20000703)422:3<396::AID-CNE6>3.0.CO;2-R  1
2000 Blesch A, Uy HS, Diergardt N, Tuszynski MH. Neurite outgrowth can be modulated in vitro using a tetracycline-repressible gene therapy vector expressing human nerve growth factor. Journal of Neuroscience Research. 59: 402-9. PMID 10679776 DOI: 10.1002/(SICI)1097-4547(20000201)59:3<402::AID-JNR14>3.0.CO;2-Q  1
2000 Tuszynski MH. Proceedings of the meeting of the American Society for Neural Transplantation and Repair (ASNTR), 1999 Cell Transplantation. 9: 565-566.  1
2000 Tuszynski MH. Spinal Cord Injury Regeneration Research: Foreword Topics in Spinal Cord Injury Rehabilitation. 6: vii-x.  1
1999 Tuszynski M, Edgerton R, Dobkin B. Recovery of locomotion after experimental spinal cord injury: axonal regeneration or modulation of intrinsic spinal cord walking circuitry? The Journal of Spinal Cord Medicine. 22: 143. PMID 10826273  1
1999 Weidner N, Grill RJ, Tuszynski MH. Elimination of basal lamina and the collagen "scar" after spinal cord injury fails to augment corticospinal tract regeneration. Experimental Neurology. 160: 40-50. PMID 10630189 DOI: 10.1006/exnr.1999.7200  1
1999 Weidner N, Blesch A, Grill RJ, Tuszynski MH. Nerve growth factor-hypersecreting Schwann cell grafts augment and guide spinal cord axonal growth and remyelinate central nervous system axons in a phenotypically appropriate manner that correlates with expression of L1. The Journal of Comparative Neurology. 413: 495-506. PMID 10495438 DOI: 10.1002/(SICI)1096-9861(19991101)413:4<495::AID-CNE1>3.0.CO;2-Z  1
1999 Smith DE, Roberts J, Gage FH, Tuszynski MH. Age-associated neuronal atrophy occurs in the primate brain and is reversible by growth factor gene therapy. Proceedings of the National Academy of Sciences of the United States of America. 96: 10893-8. PMID 10485922 DOI: 10.1073/pnas.96.19.10893  1
1999 Tuszynski MH, Gabriel K, Gerhardt K, Szollar S. Human spinal cord retains substantial structural mass in chronic stages after injury. Journal of Neurotrauma. 16: 523-31. PMID 10391368  1
1999 Blesch A, Uy HS, Grill RJ, Cheng JG, Patterson PH, Tuszynski MH. Leukemia inhibitory factor augments neurotrophin expression and corticospinal axon growth after adult CNS injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 3556-66. PMID 10212315  1
1999 Blurton-Jones MM, Roberts JA, Tuszynski MH. Estrogen receptor immunoreactivity in the adult primate brain: neuronal distribution and association with p75, trkA, and choline acetyltransferase. The Journal of Comparative Neurology. 405: 529-42. PMID 10098943 DOI: 10.1002/(SICI)1096-9861(19990322)405:4<529::AID-CNE6>3.0.CO;2-Y  1
1998 Blesch A, Grill RJ, Tuszynski MH. Neurotrophin gene therapy in CNS models of trauma and degeneration. Progress in Brain Research. 117: 473-84. PMID 9932426  1
1998 Tuszynski MH, Smith DE, Roberts J, McKay H, Mufson E. Targeted intraparenchymal delivery of human NGF by gene transfer to the primate basal forebrain for 3 months does not accelerate beta-amyloid plaque deposition. Experimental Neurology. 154: 573-82. PMID 9878192 DOI: 10.1006/exnr.1998.6956  1
1998 Tuszynski MH, Weidner N, McCormack M, Miller I, Powell H, Conner J. Grafts of genetically modified Schwann cells to the spinal cord: survival, axon growth, and myelination. Cell Transplantation. 7: 187-96. PMID 9588600 DOI: 10.1016/S0963-6897(97)00166-8  1
1998 Conner JM, Tuszynski MH. Growth factor therapy Mental Retardation and Developmental Disabilities Research Reviews. 4: 212-222. DOI: 10.1002/(SICI)1098-2779(1998)4:3<212::AID-MRDD9>3.0.CO;2-P  1
1998 Tuszynski MH. Gene therapy: Applications to the neurosciences and to neurological disease Neuroscientist. 4: 398-407.  1
1997 Tuszynski MH. Frontiers of Neurology: A Symposium in Honor of Fred Plum, Cornell University Medical College, New York, October 5 1996: Gene therapy for nervous system disease Annals of the New York Academy of Sciences. 835: 1-11. PMID 9634449 DOI: 10.1111/j.1749-6632.1997.tb48613.x  1
1997 Tuszynski MH. Gene therapy for nervous system disease. Annals of the New York Academy of Sciences. 835: 1-11. PMID 9616757  1
1997 Grill RJ, Blesch A, Tuszynski MH. Robust growth of chronically injured spinal cord axons induced by grafts of genetically modified NGF-secreting cells. Experimental Neurology. 148: 444-52. PMID 9417824 DOI: 10.1006/exnr.1997.6704  1
1997 Eberling JL, Roberts JA, Rapp PR, Tuszynski MH, Jagust WJ. Cerebral glucose metabolism and memory in aged rhesus macaques. Neurobiology of Aging. 18: 437-43. PMID 9330976 DOI: 10.1016/S0197-4580(97)00040-7  1
1997 Grill R, Murai K, Blesch A, Gage FH, Tuszynski MH. Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 5560-72. PMID 9204937  1
1997 Tuszynski MH, Murai K, Blesch A, Grill R, Miller I. Functional characterization of NGF-secreting cell grafts to the acutely injured spinal cord. Cell Transplantation. 6: 361-8. PMID 9171168 DOI: 10.1016/S0963-6897(97)00021-3  1
1997 Winkler J, Ramirez GA, Kuhn HG, Peterson DA, Day-Lollini PA, Stewart GR, Tuszynski MH, Gage FH, Thal LJ. Reversible Schwann cell hyperplasia and sprouting of sensory and sympathetic neurites after intraventricular administration of nerve growth factor. Annals of Neurology. 41: 82-93. PMID 9005869 DOI: 10.1002/ana.410410114  1
1996 Tuszynski MH, Mafong E, Meyer S. Central infusions of brain-derived neurotrophic factor and neurotrophin-4/5, but not nerve growth factor and neurotrophin-3, prevent loss of the cholinergic phenotype in injured adult motor neurons. Neuroscience. 71: 761-71. PMID 8867048 DOI: 10.1016/0306-4522(95)00440-8  1
1996 Tuszynski MH, Gage FH. Somatic gene therapy for nervous system disease. Ciba Foundation Symposium. 196: 85-94; discussion 94. PMID 8866129  1
1996 Thal LJ, Carta A, Clarke WR, Ferris SH, Friedland RP, Petersen RC, Pettegrew JW, Pfeiffer E, Raskind MA, Sano M, Tuszynski MH, Woolson RF. A 1-year multicenter placebo-controlled study of acetyl-L-carnitine in patients with Alzheimer's disease. Neurology. 47: 705-11. PMID 8797468  1
1996 Tuszynski MH, Roberts J, Senut MC, U HS, Gage FH. Gene therapy in the adult primate brain: intraparenchymal grafts of cells genetically modified to produce nerve growth factor prevent cholinergic neuronal degeneration. Gene Therapy. 3: 305-14. PMID 8732162  1
1996 Nakahara Y, Gage FH, Tuszynski MH. Grafts of fibroblasts genetically modified to secrete NGF, BDNF, NT-3, or basic FGF elicit differential responses in the adult spinal cord. Cell Transplantation. 5: 191-204. PMID 8689031 DOI: 10.1016/0963-6897(95)02028-4  1
1996 Tuszynski MH, Gabriel K, Gage FH, Suhr S, Meyer S, Rosetti A. Nerve growth factor delivery by gene transfer induces differential outgrowth of sensory, motor, and noradrenergic neurites after adult spinal cord injury. Experimental Neurology. 137: 157-73. PMID 8566208 DOI: 10.1006/exnr.1996.0016  1
1995 Blesch A, Tuszynski M. Ex vivo gene therapy for Alzheimer's disease and spinal cord injury. Clinical Neuroscience (New York, N.Y.). 3: 268-74. PMID 8914793  0.48
1995 Tuszynski MH, Gage FH. Bridging grafts and transient nerve growth factor infusions promote long-term central nervous system neuronal rescue and partial functional recovery. Proceedings of the National Academy of Sciences of the United States of America. 92: 4621-5. PMID 7753852  1
1995 Tuszynski MH, Gage FH. Maintaining the neuronal phenotype after injury in the adult CNS. Neurotrophic factors, axonal growth substrates, and gene therapy. Molecular Neurobiology. 10: 151-67. PMID 7576305 DOI: 10.1007/BF02740673  1
1995 Senut MC, Tuszynski MH, Raymon HK, Suhr ST, Liou NH, Jones KR, Reichardt LF, Gage FH. Regional differences in responsiveness of adult CNS axons to grafts of cells expressing human neurotrophin 3. Experimental Neurology. 135: 36-55. PMID 7556552 DOI: 10.1006/exnr.1995.1064  1
1994 Tuszynski MH, Senut MC, Ray J, Roberts J. Somatic gene transfer to the adult primate central nervous system: in vitro and in vivo characterization of cells genetically modified to secrete nerve growth factor. Neurobiology of Disease. 1: 67-78. PMID 9216988  1
1994 Tuszynski MH, Gage FH. Neurotrophic factors and diseases of the nervous system. Annals of Neurology. 35: S9-12. PMID 8185304 DOI: 10.1002/ana.410350705  1
1994 Tuszynski MH, Peterson DA, Ray J, Baird A, Nakahara Y, Gage FH. Fibroblasts genetically modified to produce nerve growth factor induce robust neuritic ingrowth after grafting to the spinal cord. Experimental Neurology. 126: 1-14. PMID 8157119 DOI: 10.1006/exnr.1994.1037  1
1993 Hainline B, Posner JB, Tuszynski MH. Re: Spinal cord ataxia Neurology. 43: 1623. PMID 8240525  1
1992 Hainline B, Tuszynski MH, Posner JB. Ataxia in epidural spinal cord compression. Neurology. 42: 2193-5. PMID 1436534  1
1991 Gage FH, Tuszynski MH, Chen KS, Fagan AM, Higgins GA. Nerve growth factor function in the central nervous system. Current Topics in Microbiology and Immunology. 165: 71-93. PMID 2032465  1
1991 Tuszynski MH, Gage FH. In vivo assay of neuron-specific effects of nerve growth factor. Methods in Enzymology. 198: 35-48. PMID 1857228 DOI: 10.1016/0076-6879(91)98006-R  1
1991 Tuszynski MH, Sang H, Yoshida K, Gage FH. Recombinant human nerve growth factor infusions prevent cholinergic neuronal degeneration in the adult primate brain. Annals of Neurology. 30: 625-36. PMID 1763889 DOI: 10.1002/ana.410300502  1
1990 Tuszynski MH, Armstrong DM, Gage FH. Basal forebrain cell loss following fimbria/fornix transection. Brain Research. 508: 241-8. PMID 2306615 DOI: 10.1016/0006-8993(90)90402-W  1
1990 Tuszynski MH, U HS, Amaral DG, Gage FH. Nerve growth factor infusion in the primate brain reduces lesion-induced cholinergic neuronal degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 3604-14. PMID 2230949  1
1990 TuszyÅ„ski MH, Gage FH. Potential use of neurotrophic agents in the treatment of neurodegenerative disorders. Acta Neurobiologiae Experimentalis. 50: 311-22. PMID 2130651  1
1990 Gage FH, Rosenberg MB, Tuszynski MH, Yoshida K, Armstrong DM, Hayes RC, Friedmann T. Gene therapy in the CNS: intracerebral grafting of genetically modified cells. Progress in Brain Research. 86: 205-17. PMID 2087558  1
1990 Gage FH, Fisher LJ, Jinnah HA, Rosenberg MB, Tuszynski MH, Friedmann T. Grafting genetically modified cells to the brain: conceptual and technical issues. Progress in Brain Research. 82: 1-10. PMID 1981271  0.4
1990 Tuszynski MH, Buzsaki G, Gage FH. Nerve growth factor infusions combined with fetal hippocampal grafts enhance reconstruction of the lesioned septohippocampal projection. Neuroscience. 36: 33-44. PMID 1699159 DOI: 10.1016/0306-4522(90)90349-9  1
1989 Tuszynski MH, Jinnah HA, Gage FH. Delivery of neuroactive compounds to the brain: potential utility of genetically modified cells. Neurobiology of Aging. 10: 644-5; discussion 64. PMID 2812247  0.4
1989 Chen KS, Tuszynski MH, Gage FH. Role of neurotrophic factors in Alzheimer's disease. Neurobiology of Aging. 10: 545-6; discussion 55. PMID 2812224  0.4
1989 Gage FH, Tuszynski MH, Chen KS, Armstrong D, Buzsáki G. Survival, growth and function of damaged cholinergic neurons. Exs. 57: 259-74. PMID 2533097  0.4
1988 Rosenberg MB, Friedmann T, Robertson RC, Tuszynski M, Wolff JA, Breakefield XO, Gage FH. Grafting genetically modified cells to the damaged brain: restorative effects of NGF expression. Science (New York, N.Y.). 242: 1575-8. PMID 3201248  0.4
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