David H. Rowitch - Publications

Affiliations: 
2006-2016 Department of Neonatology University of California, San Francisco, San Francisco, CA 
 2016- Department of Pediatrics University of Cambridge, Cambridge, England, United Kingdom 
Area:
oligodendrocyte, glioblastoma, stem cells
Website:
http://paediatrics.medschl.cam.ac.uk/about-us/people/senior-academic-staff/professor-david-h-rowitch/

165 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Huang W, Bhaduri A, Velmeshev D, Wang S, Wang L, Rottkamp CA, Alvarez-Buylla A, Rowitch DH, Kriegstein AR. Origins and Proliferative States of Human Oligodendrocyte Precursor Cells. Cell. PMID 32679030 DOI: 10.1016/j.cell.2020.06.027  0.395
2020 Bayraktar OA, Bartels T, Holmqvist S, Kleshchevnikov V, Martirosyan A, Polioudakis D, Ben Haim L, Young AMH, Batiuk MY, Prakash K, Brown A, Roberts K, Paredes MF, Kawaguchi R, Stockley JH, ... ... Rowitch DH, et al. Astrocyte layers in the mammalian cerebral cortex revealed by a single-cell in situ transcriptomic map. Nature Neuroscience. PMID 32203496 DOI: 10.1038/S41593-020-0602-1  0.766
2020 Kullmann JA, Trivedi N, Howell D, Laumonnerie C, Nguyen V, Banerjee SS, Stabley DR, Shirinifard A, Rowitch DH, Solecki DJ. Oxygen Tension and the VHL-Hif1α Pathway Determine Onset of Neuronal Polarization and Cerebellar Germinal Zone Exit. Neuron. PMID 32183943 DOI: 10.1016/J.Neuron.2020.02.025  0.36
2020 de Majo M, Koontz M, Rowitch D, Ullian EM. An update on human astrocytes and their role in development and disease. Glia. PMID 31926040 DOI: 10.1002/glia.23771  0.412
2020 Smith HL, Freeman OJ, Butcher AJ, Holmqvist S, Humoud I, Schätzl T, Hughes DT, Verity NC, Swinden DP, Hayes J, de Weerd L, Rowitch DH, Franklin RJM, Mallucci GR. Astrocyte Unfolded Protein Response Induces a Specific Reactivity State that Causes Non-Cell-Autonomous Neuronal Degeneration. Neuron. PMID 31924446 DOI: 10.1016/J.Neuron.2019.12.014  0.737
2019 Van Steenwinckel J, Schang AL, Krishnan ML, Degos V, Delahaye-Duriez A, Bokobza C, Csaba Z, Verdonk F, Montané A, Sigaut S, Hennebert O, Lebon S, Schwendimann L, Le Charpentier T, Hassan-Abdi R, ... ... Rowitch D, et al. Decreased microglial Wnt/β-catenin signalling drives microglial pro-inflammatory activation in the developing brain. Brain : a Journal of Neurology. PMID 31665242 DOI: 10.1093/brain/awz319  0.356
2019 Nobuta H, Yang N, Ng YH, Marro SG, Sabeur K, Chavali M, Stockley JH, Killilea DW, Walter PB, Zhao C, Huie P, Goldman SA, Kriegstein AR, Franklin RJM, Rowitch DH, et al. Oligodendrocyte Death in Pelizaeus-Merzbacher Disease Is Rescued by Iron Chelation. Cell Stem Cell. 25: 531-541.e6. PMID 31585094 DOI: 10.1016/J.Stem.2019.09.003  0.342
2019 Segel M, Neumann B, Hill MFE, Weber IP, Viscomi C, Zhao C, Young A, Agley CC, Thompson AJ, Gonzalez GA, Sharma A, Holmqvist S, Rowitch DH, Franze K, Franklin RJM, et al. Author Correction: Niche stiffness underlies the ageing of central nervous system progenitor cells. Nature. PMID 31462780 DOI: 10.1038/S41586-019-1552-1  0.711
2019 Segel M, Neumann B, Hill MFE, Weber IP, Viscomi C, Zhao C, Young A, Agley CC, Thompson AJ, Gonzalez GA, Sharma A, Holmqvist S, Rowitch DH, Franze K, Franklin RJM, et al. Niche stiffness underlies the ageing of central nervous system progenitor cells. Nature. PMID 31413369 DOI: 10.1038/S41586-019-1484-9  0.739
2019 Gupta N, Henry RG, Kang SM, Strober J, Lim DA, Ryan T, Perry R, Farrell J, Ulman M, Rajalingam R, Gage A, Huhn SL, Barkovich AJ, Rowitch DH. Long-Term Safety, Immunologic Response, and Imaging Outcomes following Neural Stem Cell Transplantation for Pelizaeus-Merzbacher Disease. Stem Cell Reports. PMID 31378671 DOI: 10.1016/J.Stemcr.2019.07.002  0.303
2019 Schirmer L, Velmeshev D, Holmqvist S, Kaufmann M, Werneburg S, Jung D, Vistnes S, Stockley JH, Young A, Steindel M, Tung B, Goyal N, Bhaduri A, Mayer S, Engler JB, ... ... Rowitch DH, et al. Neuronal vulnerability and multilineage diversity in multiple sclerosis. Nature. PMID 31316211 DOI: 10.1038/S41586-019-1404-Z  0.793
2019 Velmeshev D, Schirmer L, Jung D, Haeussler M, Perez Y, Mayer S, Bhaduri A, Goyal N, Rowitch DH, Kriegstein AR. Single-cell genomics identifies cell type-specific molecular changes in autism. Science (New York, N.Y.). 364: 685-689. PMID 31097668 DOI: 10.1126/Science.Aav8130  0.681
2019 Ellis JK, Sorrells SF, Mikhailova S, Chavali SM, Chang S, Sabeur K, McQuillen P, Rowitch DH. Ferret brain possesses young interneuron collections equivalent to human postnatal migratory streams. The Journal of Comparative Neurology. PMID 31050805 DOI: 10.1002/Cne.24711  0.362
2019 French CE, Delon I, Dolling H, Sanchis-Juan A, Shamardina O, Mégy K, Abbs S, Austin T, Bowdin S, Branco RG, Firth H, Rowitch DH, Raymond FL. Whole genome sequencing reveals that genetic conditions are frequent in intensively ill children. Intensive Care Medicine. PMID 30847515 DOI: 10.1007/S00134-019-05552-X  0.601
2019 Raymond L, French C, Delon I, Dolling H, Sanchis-Juan A, Austin T, Branco RG, Rowitch D. 803 Critical Care Medicine. 47: 380. DOI: 10.1097/01.Ccm.0000551552.66879.26  0.615
2019 Finlay J, Hallou C, Dewari P, Pollard S, Pathania M, Bulstrode H, Rowitch D. Characterising a SOX2+ OLIG2+ glioma stem cell using Crispr-engineered fluorescent reporters in primary patient-derived GBM and DIPG cells. Neuro-Oncology. 21: iv9-iv9. DOI: 10.1093/neuonc/noz167.039  0.383
2019 Seano G, Griveau A, Shelton S, Krishnan S, Wang N, Kloepper J, Huillard E, Batchelor T, Stemmer-Rachamimov A, Aghi M, Jain R, Rowitch D. OS12.4 In vivo dynamics and targeting of vessel co-option in glioma Neuro-Oncology. 21: iii23-iii23. DOI: 10.1093/Neuonc/Noz126.076  0.757
2018 Vento-Tormo R, Efremova M, Botting RA, Turco MY, Vento-Tormo M, Meyer KB, Park JE, Stephenson E, Polański K, Goncalves A, Gardner L, Holmqvist S, Henriksson J, Zou A, Sharkey AM, ... ... Rowitch DH, et al. Single-cell reconstruction of the early maternal-fetal interface in humans. Nature. 563: 347-353. PMID 30429548 DOI: 10.1038/S41586-018-0698-6  0.707
2018 Schirmer L, Möbius W, Zhao C, Cruz-Herranz A, Ben Haim L, Cordano C, Shiow LR, Kelley KW, Sadowski B, Timmons G, Pröbstel AK, Wright JN, Sin JH, Devereux M, Morrison DE, ... ... Rowitch DH, et al. Oligodendrocyte-encoded Kir4.1 function is required for axonal integrity. Elife. 7. PMID 30204081 DOI: 10.7554/Elife.36428  0.684
2018 Griveau A, Seano G, Shelton SJ, Kupp R, Jahangiri A, Obernier K, Krishnan S, Lindberg OR, Yuen TJ, Tien AC, Sabo JK, Wang N, Chen I, Kloepper J, Larrouquere L, ... ... Rowitch DH, et al. A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment. Cancer Cell. PMID 29681511 DOI: 10.1016/J.Ccell.2018.03.020  0.762
2018 Kelley KW, Ben Haim L, Schirmer L, Tyzack GE, Tolman M, Miller JG, Tsai HH, Chang SM, Molofsky AV, Yang Y, Patani R, Lakatos A, Ullian EM, Rowitch DH. Kir4.1-Dependent Astrocyte-Fast Motor Neuron Interactions Are Required for Peak Strength. Neuron. PMID 29606582 DOI: 10.1016/J.Neuron.2018.03.010  0.801
2018 Schirmer L, Möbius W, Zhao C, Cruz-Herranz A, Haim LB, Cordano C, Shiow LR, Kelley KW, Sadowski B, Timmons G, Pröbstel A, Wright JN, Sin JH, Devereux M, Morrison DE, ... ... Rowitch DH, et al. Author response: Oligodendrocyte-encoded Kir4.1 function is required for axonal integrity Elife. DOI: 10.7554/Elife.36428.020  0.66
2017 Krencik R, Seo K, van Asperen JV, Basu N, Cvetkovic C, Barlas S, Chen R, Ludwig C, Wang C, Ward ME, Gan L, Horner PJ, Rowitch DH, Ullian EM. Systematic Three-Dimensional Coculture Rapidly Recapitulates Interactions between Human Neurons and Astrocytes. Stem Cell Reports. 9: 1745-1753. PMID 29198827 DOI: 10.1016/J.Stemcr.2017.10.026  0.384
2017 Nguyen V, Sabeur K, Maltepe E, Ameri K, Bayraktar O, Rowitch DH. Sonic Hedgehog Agonist Protects Against Complex Neonatal Cerebellar Injury. Cerebellum (London, England). PMID 29134361 DOI: 10.1007/S12311-017-0895-0  0.654
2017 Petersen MA, Ryu JK, Chang KJ, Etxeberria A, Bardehle S, Mendiola AS, Kamau-Devers W, Fancy SPJ, Thor A, Bushong EA, Baeza-Raja B, Syme CA, Wu MD, Rios Coronado PE, Meyer-Franke A, ... ... Rowitch DH, et al. Fibrinogen Activates BMP Signaling in Oligodendrocyte Progenitor Cells and Inhibits Remyelination after Vascular Damage. Neuron. PMID 29103804 DOI: 10.1016/J.Neuron.2017.10.008  0.418
2017 Pla R, Stanco A, Howard MA, Rubin AN, Vogt D, Mortimer N, Cobos I, Potter GB, Lindtner S, Price JD, Nord AS, Visel A, Schreiner CE, Baraban SC, Rowitch DH, et al. Dlx1 and Dlx2 Promote Interneuron GABA Synthesis, Synaptogenesis, and Dendritogenesis. Cerebral Cortex (New York, N.Y. : 1991). 1-19. PMID 29028947 DOI: 10.1093/Cercor/Bhx241  0.725
2017 Shiow LR, Favrais G, Schirmer L, Schang AL, Cipriani S, Andres C, Wright JN, Nobuta H, Fleiss B, Gressens P, Rowitch DH. Reactive astrocyte COX2-PGE2 production inhibits oligodendrocyte maturation in neonatal white matter injury. Glia. PMID 28856805 DOI: 10.1002/Glia.23212  0.698
2017 Dawes WJ, Zhang X, Fancy SP, Rowitch D, Marino S. Moderate-Grade Germinal Matrix Haemorrhage Activates Cell Division in the Neonatal Mouse Subventricular Zone. Developmental Neuroscience. PMID 28343214 DOI: 10.1159/000455839  0.751
2017 Sabo JK, Heine V, Silbereis JC, Schirmer L, Levison SW, Rowitch DH. Olig1 is required for Noggin-induced neonatal myelin repair. Annals of Neurology. PMID 28253550 DOI: 10.1002/Ana.24907  0.704
2017 Liddelow SA, Guttenplan KA, Clarke LE, Bennett FC, Bohlen CJ, Schirmer L, Bennett ML, Münch AE, Chung WS, Peterson TC, Wilton DK, Frouin A, Napier BA, Panicker N, Kumar M, ... ... Rowitch DH, et al. Neurotoxic reactive astrocytes are induced by activated microglia. Nature. PMID 28099414 DOI: 10.1038/Nature21029  0.681
2017 Schirmer L, Liesche F, Barz M, Bette S, Wiestler B, Srivastava R, Zimmer C, Ringel F, Rowitch D, Meyer B, Hemmer B, Schlegel J, Gempt J. TMIC-49. POTASSIUM CHANNEL KIR4.1 AND GLUTAMINE SYNTHETASE ARE DYSREGULATED IN GLIOMA Neuro-Oncology. 19: vi253-vi254. DOI: 10.1093/NEUONC/NOX168.1037  0.611
2016 Jablonska B, Gierdalski M, Chew LJ, Hawley T, Catron M, Lichauco A, Cabrera-Luque J, Yuen T, Rowitch D, Gallo V. Sirt1 regulates glial progenitor proliferation and regeneration in white matter after neonatal brain injury. Nature Communications. 7: 13866. PMID 27991597 DOI: 10.1038/ncomms13866  0.419
2016 Osorio MJ, Rowitch DH, Tesar P, Wernig M, Windrem MS, Goldman SA. Concise Review: Stem Cell-Based Treatment of Pelizaeus-Merzbacher Disease. Stem Cells (Dayton, Ohio). PMID 27882623 DOI: 10.1002/Stem.2530  0.384
2016 Paredes MF, James D, Gil-Perotin S, Kim H, Cotter JA, Ng C, Sandoval K, Rowitch DH, Xu D, McQuillen PS, Garcia-Verdugo JM, Huang EJ, Alvarez-Buylla A. Extensive migration of young neurons into the infant human frontal lobe. Science (New York, N.Y.). 354. PMID 27846470 DOI: 10.1126/Science.Aaf7073  0.36
2016 Kupp R, Shtayer L, Tien AC, Szeto E, Sanai N, Rowitch DH, Mehta S. Lineage-Restricted OLIG2-RTK Signaling Governs the Molecular Subtype of Glioma Stem-like Cells. Cell Reports. 16: 2838-2845. PMID 27626655 DOI: 10.1016/J.Celrep.2016.08.040  0.344
2016 Mei F, Mayoral SR, Nobuta H, Wang F, Desponts C, Lorrain DS, Xiao L, Green AJ, Rowitch D, Whistler J, Chan JR. Identification of the Kappa-Opioid Receptor as a Therapeutic Target for Oligodendrocyte Remyelination. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 7925-35. PMID 27466337 DOI: 10.1523/Jneurosci.1493-16.2016  0.359
2016 Lindquist RA, Guinto CD, Rodas-Rodriguez JL, Fuentealba LC, Tate MC, Rowitch DH, Alvarez-Buylla A. Identification of proliferative progenitors associated with prominent postnatal growth of the pons. Nature Communications. 7: 11628. PMID 27188978 DOI: 10.1038/Ncomms11628  0.352
2016 Kelley KW, Rowitch DH. Astrocytes: The Final Frontier…. Neuron. 89: 1-2. PMID 26748083 DOI: 10.1016/j.neuron.2015.12.030  0.308
2015 Nobuta H, Cilio MR, Danhaive O, Tsai HH, Tupal S, Chang SM, Murnen A, Kreitzer F, Bravo V, Czeisler C, Gokozan HN, Gygli P, Bush S, Weese-Mayer DE, Conklin B, ... ... Rowitch D, et al. Dysregulation of locus coeruleus development in congenital central hypoventilation syndrome. Acta Neuropathologica. 130: 171-83. PMID 25975378 DOI: 10.1007/S00401-015-1441-0  0.66
2015 Krencik R, Hokanson KC, Narayan AR, Dvornik J, Rooney GE, Rauen KA, Weiss LA, Rowitch DH, Ullian EM. Dysregulation of astrocyte extracellular signaling in Costello syndrome. Science Translational Medicine. 7: 286ra66. PMID 25947161 DOI: 10.1126/Scitranslmed.Aaa5645  0.412
2015 Helman G, Van Haren K, Bonkowsky JL, Bernard G, Pizzino A, Braverman N, Suhr D, Patterson MC, Ali Fatemi S, Leonard J, van der Knaap MS, Back SA, Damiani S, Goldman SA, Takanohashi A, ... ... Rowitch D, et al. Disease specific therapies in leukodystrophies and leukoencephalopathies. Molecular Genetics and Metabolism. 114: 527-36. PMID 25684057 DOI: 10.1016/J.Ymgme.2015.01.014  0.761
2015 Bayraktar OA, Fuentealba LC, Alvarez-Buylla A, Rowitch DH. Astrocyte development and heterogeneity. Cold Spring Harbor Perspectives in Biology. 7: a020362. PMID 25414368 DOI: 10.1101/Cshperspect.A020362  0.697
2015 Tate MC, Lindquist RA, Nguyen T, Sanai N, Barkovich AJ, Huang EJ, Rowitch DH, Alvarez-Buylla A. Postnatal growth of the human pons: a morphometric and immunohistochemical analysis. The Journal of Comparative Neurology. 523: 449-62. PMID 25307966 DOI: 10.1002/Cne.23690  0.386
2015 Griveau A, Shelton S, Tien A, Seano G, Yuen T, Sabo J, Lau J, Jahangiri A, Huillard E, Phillips J, Persson A, Oldham M, Weiss W, Aghi M, Stiles C, ... ... Rowitch D, et al. ANGI-04Olig2 REGULATES Wnt7b EXPRESSION AND VASCULATURE CHARACTERISTICS IN GLIOMA Neuro-Oncology. 17: v41.4-v41. DOI: 10.1093/Neuonc/Nov207.04  0.758
2014 Yuen TJ, Silbereis JC, Griveau A, Chang SM, Daneman R, Fancy SP, Zahed H, Maltepe E, Rowitch DH. Oligodendrocyte-encoded HIF function couples postnatal myelination and white matter angiogenesis. Cell. 158: 383-96. PMID 25018103 DOI: 10.1016/J.Cell.2014.04.052  0.762
2014 Meijer DH, Sun Y, Liu T, Kane MF, Alberta JA, Adelmant G, Kupp R, Marto JA, Rowitch DH, Nakatani Y, Stiles CD, Mehta S. An amino terminal phosphorylation motif regulates intranuclear compartmentalization of Olig2 in neural progenitor cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 8507-18. PMID 24948806 DOI: 10.1523/Jneurosci.0309-14.2014  0.402
2014 Molofsky AV, Kelley KW, Tsai HH, Redmond SA, Chang SM, Madireddy L, Chan JR, Baranzini SE, Ullian EM, Rowitch DH. Astrocyte-encoded positional cues maintain sensorimotor circuit integrity. Nature. 509: 189-94. PMID 24776795 DOI: 10.1038/Nature13161  0.742
2014 Fancy SP, Harrington EP, Baranzini SE, Silbereis JC, Shiow LR, Yuen TJ, Huang EJ, Lomvardas S, Rowitch DH. Parallel states of pathological Wnt signaling in neonatal brain injury and colon cancer. Nature Neuroscience. 17: 506-12. PMID 24609463 DOI: 10.1038/Nn.3676  0.802
2014 Silbereis JC, Nobuta H, Tsai HH, Heine VM, McKinsey GL, Meijer DH, Howard MA, Petryniak MA, Potter GB, Alberta JA, Baraban SC, Stiles CD, Rubenstein JL, Rowitch DH. Olig1 function is required to repress dlx1/2 and interneuron production in Mammalian brain. Neuron. 81: 574-87. PMID 24507192 DOI: 10.1016/J.Neuron.2013.11.024  0.79
2014 Otero JJ, Kalaszczynska I, Michowski W, Wong M, Gygli PE, Gokozan HN, Griveau A, Odajima J, Czeisler C, Catacutan FP, Murnen A, Schüller U, Sicinski P, Rowitch D. Cerebellar cortical lamination and foliation require cyclin A2. Developmental Biology. 385: 328-39. PMID 24184637 DOI: 10.1016/J.Ydbio.2013.10.019  0.617
2014 Lerner RG, Ihara Y, Lewis K, Griveau A, Reichhold B, Qu D, McMahon M, Rowitch D, James CD, Petritsch C. Abstract 1944: Divergent effects of BRAF activation in neural stem and progenitor-like glioblastoma cells Cancer Research. 74: 1944-1944. DOI: 10.1158/1538-7445.Am2014-1944  0.376
2014 Fancy SPJ, Harrington EP, Baranzini SE, Silbereis JC, Shiow LR, Yuen TJ, Huang EJ, Lomvardas S, Rowitch DH. Erratum: Corrigendum: Parallel states of pathological Wnt signaling in neonatal brain injury and colon cancer Nature Neuroscience. 17: 1841-1841. DOI: 10.1038/Nn1214-1841A  0.596
2013 Achim K, Peltopuro P, Lahti L, Tsai HH, Zachariah A, Astrand M, Salminen M, Rowitch D, Partanen J. The role of Tal2 and Tal1 in the differentiation of midbrain GABAergic neuron precursors. Biology Open. 2: 990-7. PMID 24167708 DOI: 10.1242/Bio.20135041  0.371
2013 Stephan AH, Madison DV, Mateos JM, Fraser DA, Lovelett EA, Coutellier L, Kim L, Tsai HH, Huang EJ, Rowitch DH, Berns DS, Tenner AJ, Shamloo M, Barres BA. A dramatic increase of C1q protein in the CNS during normal aging. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 13460-74. PMID 23946404 DOI: 10.1523/Jneurosci.1333-13.2013  0.31
2013 Molofsky AV, Glasgow SM, Chaboub LS, Tsai HH, Murnen AT, Kelley KW, Fancy SP, Yuen TJ, Madireddy L, Baranzini S, Deneen B, Rowitch DH, Oldham MC. Expression profiling of Aldh1l1-precursors in the developing spinal cord reveals glial lineage-specific genes and direct Sox9-Nfe2l1 interactions. Glia. 61: 1518-32. PMID 23840004 DOI: 10.1002/Glia.22538  0.812
2013 Potter GB, Santos M, Davisson MT, Rowitch DH, Marks DL, Bongarzone ER, Petryniak MA. Missense mutation in mouse GALC mimics human gene defect and offers new insights into Krabbe disease. Human Molecular Genetics. 22: 3397-414. PMID 23620143 DOI: 10.1093/Hmg/Ddt190  0.783
2013 Molofsky AV, Hochstim C, Deneen B, Rowitch D. Mechanisms of Astrocyte Development Comprehensive Developmental Neuroscience: Patterning and Cell Type Specification in the Developing Cns and Pns. 723-742. DOI: 10.1016/B978-0-12-397265-1.00080-0  0.693
2012 Meijer DH, Kane MF, Mehta S, Liu H, Harrington E, Taylor CM, Stiles CD, Rowitch DH. Separated at birth? The functional and molecular divergence of OLIG1 and OLIG2. Nature Reviews. Neuroscience. 13: 819-31. PMID 23165259 DOI: 10.1038/Nrn3386  0.682
2012 Jablonska B, Scafidi J, Aguirre A, Vaccarino F, Nguyen V, Borok E, Horvath TL, Rowitch DH, Gallo V. Oligodendrocyte regeneration after neonatal hypoxia requires FoxO1-mediated p27Kip1 expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 14775-93. PMID 23077062 DOI: 10.1523/Jneurosci.2060-12.2012  0.386
2012 Gupta N, Henry RG, Strober J, Kang SM, Lim DA, Bucci M, Caverzasi E, Gaetano L, Mandelli ML, Ryan T, Perry R, Farrell J, Jeremy RJ, Ulman M, Huhn SL, ... ... Rowitch DH, et al. Neural stem cell engraftment and myelination in the human brain. Science Translational Medicine. 4: 155ra137. PMID 23052294 DOI: 10.1126/Scitranslmed.3004373  0.349
2012 Nobuta H, Ghiani CA, Paez PM, Spreuer V, Dong H, Korsak RA, Manukyan A, Li J, Vinters HV, Huang EJ, Rowitch DH, Sofroniew MV, Campagnoni AT, de Vellis J, Waschek JA. STAT3-mediated astrogliosis protects myelin development in neonatal brain injury. Annals of Neurology. 72: 750-65. PMID 22941903 DOI: 10.1002/Ana.23670  0.422
2012 Huang X, Dubuc AM, Hashizume R, Berg J, He Y, Wang J, Chiang C, Cooper MK, Northcott PA, Taylor MD, Barnes MJ, Tihan T, Chen J, Hackett CS, Weiss WA, ... ... Rowitch DH, et al. Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics. Genes & Development. 26: 1780-96. PMID 22855790 DOI: 10.1101/Gad.193789.112  0.324
2012 Fancy SP, Glasgow SM, Finley M, Rowitch DH, Deneen B. Evidence that nuclear factor IA inhibits repair after white matter injury. Annals of Neurology. 72: 224-33. PMID 22807310 DOI: 10.1002/Ana.23590  0.778
2012 Tsai HH, Li H, Fuentealba LC, Molofsky AV, Taveira-Marques R, Zhuang H, Tenney A, Murnen AT, Fancy SP, Merkle F, Kessaris N, Alvarez-Buylla A, Richardson WD, Rowitch DH. Regional astrocyte allocation regulates CNS synaptogenesis and repair. Science (New York, N.Y.). 337: 358-62. PMID 22745251 DOI: 10.1126/Science.1222381  0.801
2012 Tien AC, Tsai HH, Molofsky AV, McMahon M, Foo LC, Kaul A, Dougherty JD, Heintz N, Gutmann DH, Barres BA, Rowitch DH. Regulated temporal-spatial astrocyte precursor cell proliferation involves BRAF signalling in mammalian spinal cord. Development (Cambridge, England). 139: 2477-87. PMID 22675209 DOI: 10.1242/Jcs.116657  0.748
2012 Huillard E, Hashizume R, Phillips JJ, Griveau A, Ihrie RA, Aoki Y, Nicolaides T, Perry A, Waldman T, McMahon M, Weiss WA, Petritsch C, James CD, Rowitch DH. Cooperative interactions of BRAFV600E kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy. Proceedings of the National Academy of Sciences of the United States of America. 109: 8710-5. PMID 22586120 DOI: 10.1073/Pnas.1117255109  0.729
2012 Kwan KY, Lam MM, Johnson MB, Dube U, Shim S, RaÅ¡in MR, Sousa AM, Fertuzinhos S, Chen JG, Arellano JI, Chan DW, Pletikos M, Vasung L, Rowitch DH, Huang EJ, et al. Species-dependent posttranscriptional regulation of NOS1 by FMRP in the developing cerebral cortex. Cell. 149: 899-911. PMID 22579290 DOI: 10.1016/J.Cell.2012.02.060  0.359
2012 Molofsky AV, Krencik R, Krenick R, Ullian EM, Ullian E, Tsai HH, Deneen B, Richardson WD, Barres BA, Rowitch DH. Astrocytes and disease: a neurodevelopmental perspective. Genes & Development. 26: 891-907. PMID 22549954 DOI: 10.1101/Gad.188326.112  0.731
2012 Yu J, Valerius MT, Duah M, Staser K, Hansard JK, Guo JJ, McMahon J, Vaughan J, Faria D, Georgas K, Rumballe B, Ren Q, Krautzberger AM, Junker JP, Thiagarajan RD, ... ... Rowitch DH, et al. Identification of molecular compartments and genetic circuitry in the developing mammalian kidney. Development (Cambridge, England). 139: 1863-73. PMID 22510988 DOI: 10.1242/Dev.074005  0.559
2012 Whitman LM, Blanc CA, Schaumburg CS, Rowitch DH, Lane TE. Olig1 function is required for remyelination potential of transplanted neural progenitor cells in a model of viral-induced demyelination Experimental Neurology. 235: 380-387. PMID 22449475 DOI: 10.1016/j.expneurol.2012.03.003  0.416
2012 Phillips JJ, Huillard E, Robinson AE, Ward A, Lum DH, Polley MY, Rosen SD, Rowitch DH, Werb Z. Heparan sulfate sulfatase SULF2 regulates PDGFRα signaling and growth in human and mouse malignant glioma. The Journal of Clinical Investigation. 122: 911-22. PMID 22293178 DOI: 10.1172/Jci58215  0.744
2012 Chong SY, Rosenberg SS, Fancy SP, Zhao C, Shen YA, Hahn AT, McGee AW, Xu X, Zheng B, Zhang LI, Rowitch DH, Franklin RJ, Lu QR, Chan JR. Neurite outgrowth inhibitor Nogo-A establishes spatial segregation and extent of oligodendrocyte myelination. Proceedings of the National Academy of Sciences of the United States of America. 109: 1299-304. PMID 22160722 DOI: 10.1073/Pnas.1113540109  0.75
2012 Papagiannakopoulos T, Friedmann-Morvinski D, Neveu P, Dugas JC, Gill RM, Huillard E, Liu C, Zong H, Rowitch DH, Barres BA, Verma IM, Kosik KS. Pro-neural miR-128 is a glioma tumor suppressor that targets mitogenic kinases. Oncogene. 31: 1884-95. PMID 21874051 DOI: 10.1038/Onc.2011.380  0.722
2012 Tien AC, Tsai HH, Molofsky AV, McMahon M, Foo LC, Kaul A, Dougherty JD, Heintz N, Gutmann DH, Barres BA, Rowitch DH. Regulated temporal-spatial astrocyte precursor cell proliferation involves BRAF signalling in mammalian spinal cord Journal of Cell Science. 125: 2477-2487.  0.695
2011 Nicolaides TP, Li H, Solomon DA, Hariono S, Hashizume R, Barkovich K, Baker SJ, Paugh BS, Jones C, Forshew T, Hindley GF, Hodgson JG, Kim JS, Rowitch DH, Weiss WA, et al. Targeted therapy for BRAFV600E malignant astrocytoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 7595-604. PMID 22038996 DOI: 10.1158/1078-0432.Ccr-11-1456  0.311
2011 Heine VM, Griveau A, Chapin C, Ballard PL, Chen JK, Rowitch DH. A small-molecule smoothened agonist prevents glucocorticoid-induced neonatal cerebellar injury. Science Translational Medicine. 3: 105ra104. PMID 22013124 DOI: 10.1126/Scitranslmed.3002731  0.332
2011 Sanai N, Nguyen T, Ihrie RA, Mirzadeh Z, Tsai HH, Wong M, Gupta N, Berger MS, Huang E, Garcia-Verdugo JM, Rowitch DH, Alvarez-Buylla A. Corridors of migrating neurons in the human brain and their decline during infancy. Nature. 478: 382-6. PMID 21964341 DOI: 10.1038/Nature10487  0.368
2011 Huang JK, Fancy SP, Zhao C, Rowitch DH, Ffrench-Constant C, Franklin RJ. Myelin regeneration in multiple sclerosis: targeting endogenous stem cells. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 8: 650-8. PMID 21904791 DOI: 10.1007/S13311-011-0065-X  0.746
2011 Fancy SP, Harrington EP, Yuen TJ, Silbereis JC, Zhao C, Baranzini SE, Bruce CC, Otero JJ, Huang EJ, Nusse R, Franklin RJ, Rowitch DH. Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination. Nature Neuroscience. 14: 1009-16. PMID 21706018 DOI: 10.1038/Nn.2855  0.811
2011 Fancy SP, Chan JR, Baranzini SE, Franklin RJ, Rowitch DH. Myelin regeneration: a recapitulation of development? Annual Review of Neuroscience. 34: 21-43. PMID 21692657 DOI: 10.1146/Annurev-Neuro-061010-113629  0.747
2011 Potter GB, Rowitch DH, Petryniak MA. Myelin restoration: progress and prospects for human cell replacement therapies. Archivum Immunologiae Et Therapiae Experimentalis. 59: 179-93. PMID 21461592 DOI: 10.1007/S00005-011-0120-7  0.8
2011 Mehta S, Huillard E, Kesari S, Maire CL, Golebiowski D, Harrington EP, Alberta JA, Kane MF, Theisen M, Ligon KL, Rowitch DH, Stiles CD. The central nervous system-restricted transcription factor Olig2 opposes p53 responses to genotoxic damage in neural progenitors and malignant glioma. Cancer Cell. 19: 359-71. PMID 21397859 DOI: 10.1016/J.Ccr.2011.01.035  0.78
2011 Sun Y, Meijer DH, Alberta JA, Mehta S, Kane MF, Tien AC, Fu H, Petryniak MA, Potter GB, Liu Z, Powers JF, Runquist IS, Rowitch DH, Stiles CD. Phosphorylation state of Olig2 regulates proliferation of neural progenitors. Neuron. 69: 906-17. PMID 21382551 DOI: 10.1016/J.Neuron.2011.02.005  0.805
2011 Monje M, Mitra SS, Freret ME, Raveh TB, Kim J, Masek M, Attema JL, Li G, Haddix T, Edwards MS, Fisher PG, Weissman IL, Rowitch DH, Vogel H, Wong AJ, et al. Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma. Proceedings of the National Academy of Sciences of the United States of America. 108: 4453-8. PMID 21368213 DOI: 10.1073/Pnas.1101657108  0.358
2011 Otero JJ, Rowitch D, Vandenberg S. OLIG2 is differentially expressed in pediatric astrocytic and in ependymal neoplasms. Journal of Neuro-Oncology. 104: 423-38. PMID 21193945 DOI: 10.1007/S11060-010-0509-X  0.611
2011 Biran V, Heine VM, Verney C, Sheldon RA, Spadafora R, Vexler ZS, Rowitch DH, Ferriero DM. Cerebellar abnormalities following hypoxia alone compared to hypoxic-ischemic forebrain injury in the developing rat brain. Neurobiology of Disease. 41: 138-46. PMID 20843479 DOI: 10.1016/j.nbd.2010.09.001  0.301
2010 Rowitch DH, Kriegstein AR. Developmental genetics of vertebrate glial-cell specification. Nature. 468: 214-22. PMID 21068830 DOI: 10.1038/nature09611  0.433
2010 Harrington EP, Zhao C, Fancy SP, Kaing S, Franklin RJ, Rowitch DH. Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination. Annals of Neurology. 68: 703-16. PMID 20853437 DOI: 10.1002/Ana.22090  0.804
2010 Maunakea AK, Nagarajan RP, Bilenky M, Ballinger TJ, D'Souza C, Fouse SD, Johnson BE, Hong C, Nielsen C, Zhao Y, Turecki G, Delaney A, Varhol R, Thiessen N, Shchors K, ... ... Rowitch DH, et al. Conserved role of intragenic DNA methylation in regulating alternative promoters. Nature. 466: 253-7. PMID 20613842 DOI: 10.1038/Nature09165  0.305
2010 Zawadzka M, Rivers LE, Fancy SP, Zhao C, Tripathi R, Jamen F, Young K, Goncharevich A, Pohl H, Rizzi M, Rowitch DH, Kessaris N, Suter U, Richardson WD, Franklin RJ. CNS-resident glial progenitor/stem cells produce Schwann cells as well as oligodendrocytes during repair of CNS demyelination. Cell Stem Cell. 6: 578-90. PMID 20569695 DOI: 10.1016/J.Stem.2010.04.002  0.778
2010 de la Torre-Ubieta L, Gaudillière B, Yang Y, Ikeuchi Y, Yamada T, DiBacco S, Stegmüller J, Schüller U, Salih DA, Rowitch D, Brunet A, Bonni A. A FOXO-Pak1 transcriptional pathway controls neuronal polarity. Genes & Development. 24: 799-813. PMID 20395366 DOI: 10.1101/Gad.1880510  0.35
2010 Fancy SP, Kotter MR, Harrington EP, Huang JK, Zhao C, Rowitch DH, Franklin RJ. Overcoming remyelination failure in multiple sclerosis and other myelin disorders. Experimental Neurology. 225: 18-23. PMID 20044992 DOI: 10.1016/J.Expneurol.2009.12.020  0.802
2010 Ihrie RA, Huillard E, Petritsch C, James D, McMahon M, Gutmann DH, Rowitch DH, Alvarez-Buylla A. Abstract 4186: Development of a novel, genetically faithful model of pediatric glioblastoma Cancer Research. 70: 4186-4186. DOI: 10.1158/1538-7445.Am10-4186  0.711
2009 Zhang Y, Argaw AT, Gurfein BT, Zameer A, Snyder BJ, Ge C, Lu QR, Rowitch DH, Raine CS, Brosnan CF, John GR. Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination. Proceedings of the National Academy of Sciences of the United States of America. 106: 19162-7. PMID 19855010 DOI: 10.1073/Pnas.0902834106  0.413
2009 Fu H, Cai J, Clevers H, Fast E, Gray S, Greenberg R, Jain MK, Ma Q, Qiu M, Rowitch DH, Taylor CM, Stiles CD. A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 11399-408. PMID 19741146 DOI: 10.1523/Jneurosci.0160-09.2009  0.39
2009 Hyman JM, Firestone AJ, Heine VM, Zhao Y, Ocasio CA, Han K, Sun M, Rack PG, Sinha S, Wu JJ, Solow-Cordero DE, Jiang J, Rowitch DH, Chen JK. Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade. Proceedings of the National Academy of Sciences of the United States of America. 106: 14132-7. PMID 19666565 DOI: 10.1073/Pnas.0907134106  0.339
2009 Emery B, Agalliu D, Cahoy JD, Watkins TA, Dugas JC, Mulinyawe SB, Ibrahim A, Ligon KL, Rowitch DH, Barres BA. Myelin gene regulatory factor is a critical transcriptional regulator required for CNS myelination. Cell. 138: 172-85. PMID 19596243 DOI: 10.1016/J.Cell.2009.04.031  0.425
2009 Fancy SP, Baranzini SE, Zhao C, Yuk DI, Irvine KA, Kaing S, Sanai N, Franklin RJ, Rowitch DH. Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS. Genes & Development. 23: 1571-85. PMID 19515974 DOI: 10.1101/Gad.1806309  0.761
2009 Kim AH, Puram SV, Bilimoria PM, Ikeuchi Y, Keough S, Wong M, Rowitch D, Bonni A. A centrosomal Cdc20-APC pathway controls dendrite morphogenesis in postmitotic neurons. Cell. 136: 322-36. PMID 19167333 DOI: 10.1016/J.Cell.2008.11.050  0.358
2008 Yang ZJ, Ellis T, Markant SL, Read TA, Kessler JD, Bourboulas M, Schüller U, Machold R, Fishell G, Rowitch DH, Wainwright BJ, Wechsler-Reya RJ. Medulloblastoma can be initiated by deletion of Patched in lineage-restricted progenitors or stem cells. Cancer Cell. 14: 135-45. PMID 18691548 DOI: 10.1016/J.Ccr.2008.07.003  0.385
2008 Schüller U, Heine VM, Mao J, Kho AT, Dillon AK, Han YG, Huillard E, Sun T, Ligon AH, Qian Y, Ma Q, Alvarez-Buylla A, McMahon AP, Rowitch DH, Ligon KL. Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma. Cancer Cell. 14: 123-34. PMID 18691547 DOI: 10.1016/J.Ccr.2008.07.005  0.812
2008 Hafler BP, Choi MY, Shivdasani RA, Rowitch DH. Expression and function of Nkx6.3 in vertebrate hindbrain Brain Research. 1222: 42-50. PMID 18586225 DOI: 10.1016/J.Brainres.2008.04.072  0.796
2008 Stiles CD, Rowitch DH. Glioma stem cells: a midterm exam. Neuron. 58: 832-46. PMID 18579075 DOI: 10.1016/j.neuron.2008.05.031  0.334
2008 Billiards SS, Haynes RL, Folkerth RD, Borenstein NS, Trachtenberg FL, Rowitch DH, Ligon KL, Volpe JJ, Kinney HC. Myelin abnormalities without oligodendrocyte loss in periventricular leukomalacia. Brain Pathology (Zurich, Switzerland). 18: 153-63. PMID 18177464 DOI: 10.1111/J.1750-3639.2007.00107.X  0.386
2007 Schüller U, Zhao Q, Godinho SA, Heine VM, Medema RH, Pellman D, Rowitch DH. Forkhead transcription factor FoxM1 regulates mitotic entry and prevents spindle defects in cerebellar granule neuron precursors. Molecular and Cellular Biology. 27: 8259-70. PMID 17893320 DOI: 10.1128/Mcb.00707-07  0.4
2007 Del Barrio MG, Taveira-Marques R, Muroyama Y, Yuk DI, Li S, Wines-Samuelson M, Shen J, Smith HK, Xiang M, Rowitch D, Richardson WD. A regulatory network involving Foxn4, Mash1 and delta-like 4/Notch1 generates V2a and V2b spinal interneurons from a common progenitor pool. Development (Cambridge, England). 134: 3427-36. PMID 17728344 DOI: 10.1242/Dev.005868  0.412
2007 Petryniak MA, Potter GB, Rowitch DH, Rubenstein JL. Dlx1 and Dlx2 control neuronal versus oligodendroglial cell fate acquisition in the developing forebrain. Neuron. 55: 417-33. PMID 17678855 DOI: 10.1016/J.Neuron.2007.06.036  0.808
2007 Parras CM, Hunt C, Sugimori M, Nakafuku M, Rowitch D, Guillemot F. The proneural gene Mash1 specifies an early population of telencephalic oligodendrocytes Journal of Neuroscience. 27: 4233-4242. PMID 17442807 DOI: 10.1523/JNEUROSCI.0126-07.2007  0.429
2007 Ligon KL, Huillard E, Mehta S, Kesari S, Liu H, Alberta JA, Bachoo RM, Kane M, Louis DN, Depinho RA, Anderson DJ, Stiles CD, Rowitch DH. Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma. Neuron. 53: 503-17. PMID 17296553 DOI: 10.1016/J.Neuron.2007.01.009  0.773
2007 Zeger M, Popken G, Zhang J, Xuan S, Lu QR, Schwab MH, Nave KA, Rowitch D, D'Ercole AJ, Ye P. Insulin-like growth factor type 1 receptor signaling in the cells of oligodendrocyte lineage is required for normal in vivo oligodendrocyte development and myelination. Glia. 55: 400-11. PMID 17186502 DOI: 10.1002/glia.20469  0.388
2006 Rousseau A, Nutt CL, Betensky RA, Iafrate AJ, Han M, Ligon KL, Rowitch DH, Louis DN. Expression of oligodendroglial and astrocytic lineage markers in diffuse gliomas: use of YKL-40, ApoE, ASCL1, and NKX2-2. Journal of Neuropathology and Experimental Neurology. 65: 1149-56. PMID 17146289 DOI: 10.1097/01.Jnen.0000248543.90304.2B  0.359
2006 Mao J, Ligon KL, Rakhlin EY, Thayer SP, Bronson RT, Rowitch D, McMahon AP. A novel somatic mouse model to survey tumorigenic potential applied to the Hedgehog pathway. Cancer Research. 66: 10171-8. PMID 17047082 DOI: 10.1158/0008-5472.Can-06-0657  0.52
2006 Schüller U, Kho AT, Zhao Q, Ma Q, Rowitch DH. Cerebellar 'transcriptome' reveals cell-type and stage-specific expression during postnatal development and tumorigenesis Molecular and Cellular Neuroscience. 33: 247-259. PMID 16962790 DOI: 10.1016/J.Mcn.2006.07.010  0.434
2006 Hatton BA, Knoepfler PS, Kenney AM, Rowitch DH, de Alborán IM, Olson JM, Eisenman RN. N-myc is an essential downstream effector of Shh signaling during both normal and neoplastic cerebellar growth. Cancer Research. 66: 8655-61. PMID 16951180 DOI: 10.1158/0008-5472.Can-06-1621  0.328
2006 Menn B, Garcia-Verdugo JM, Yaschine C, Gonzalez-Perez O, Rowitch D, Alvarez-Buylla A. Origin of oligodendrocytes in the subventricular zone of the adult brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 7907-18. PMID 16870736 DOI: 10.1523/JNEUROSCI.1299-06.2006  0.445
2006 Ligon KL, Kesari S, Kitada M, Sun T, Arnett HA, Alberta JA, Anderson DJ, Stiles CD, Rowitch DH. Development of NG2 neural progenitor cells requires Olig gene function. Proceedings of the National Academy of Sciences of the United States of America. 103: 7853-8. PMID 16682644 DOI: 10.1073/Pnas.0511001103  0.442
2006 Ligon KL, Fancy SP, Franklin RJ, Rowitch DH. Olig gene function in CNS development and disease. Glia. 54: 1-10. PMID 16652341 DOI: 10.1002/Glia.20273  0.786
2006 Sun T, Hafler BP, Kaing S, Kitada M, Ligon KL, Widlund HR, Yuk DI, Stiles CD, Rowitch DH. Evidence for motoneuron lineage-specific regulation of Olig2 in the vertebrate neural tube. Developmental Biology. 292: 152-64. PMID 16469306 DOI: 10.1016/J.Ydbio.2005.12.047  0.797
2005 Buffo A, Vosko MR, Ertürk D, Hamann GF, Jucker M, Rowitch D, Götz M. Expression pattern of the transcription factor Olig2 in response to brain injuries: Implications for neuronal repair Proceedings of the National Academy of Sciences of the United States of America. 102: 18183-18188. PMID 16330768 DOI: 10.1073/Pnas.0506535102  0.39
2005 Muroyama Y, Fujiwara Y, Orkin SH, Rowitch DH. Specification of astrocytes by bHLH protein SCL in a restricted region of the neural tube Nature. 438: 360-363. PMID 16292311 DOI: 10.1038/Nature04139  0.466
2005 Matei V, Pauley S, Kaing S, Rowitch D, Beisel KW, Morris K, Feng F, Jones K, Lee J, Fritzsch B. Smaller inner ear sensory epithelia in Neurog 1 null mice are related to earlier hair cell cycle exit. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 234: 633-50. PMID 16145671 DOI: 10.1002/Dvdy.20551  0.379
2004 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, ... ... Rowitch DH, et al. Mouse brain organization revealed through direct genome-scale TF expression analysis. Science (New York, N.Y.). 306: 2255-7. PMID 15618518 DOI: 10.1126/Science.1104935  0.789
2004 Arnett HA, Fancy SP, Alberta JA, Zhao C, Plant SR, Kaing S, Raine CS, Rowitch DH, Franklin RJ, Stiles CD. bHLH transcription factor Olig1 is required to repair demyelinated lesions in the CNS. Science (New York, N.Y.). 306: 2111-5. PMID 15604411 DOI: 10.1126/Science.1103709  0.774
2004 Ligon KL, Alberta JA, Kho AT, Weiss J, Kwaan MR, Nutt CL, Louis DN, Stiles CD, Rowitch DH. The oligodendroglial lineage marker OLIG2 is universally expressed in diffuse gliomas. Journal of Neuropathology and Experimental Neurology. 63: 499-509. PMID 15198128 DOI: 10.1093/Jnen/63.5.499  0.368
2004 Bachoo RM, Kim RS, Ligon KL, Maher EA, Brennan C, Billings N, Chan S, Li C, Rowitch DH, Wong WH, DePinho RA. Molecular diversity of astrocytes with implications for neurological disorders. Proceedings of the National Academy of Sciences of the United States of America. 101: 8384-9. PMID 15155908 DOI: 10.1073/Pnas.0402140101  0.799
2004 Akiyama H, Chaboissier MC, Behringer RR, Rowitch DH, Schedl A, Epstein JA, De Crombrugghe B. Essential role of Sox9 in the pathway that controls formation of cardiac valves and septa Proceedings of the National Academy of Sciences of the United States of America. 101: 6502-6507. PMID 15096597 DOI: 10.1073/Pnas.0401711101  0.337
2004 Kho AT, Zhao Q, Cai Z, Butte AJ, Kim JY, Pomeroy SL, Rowitch DH, Kohane IS. Conserved mechanisms across development and tumorigenesis revealed by a mouse development perspective of human cancers. Genes & Development. 18: 629-40. PMID 15075291 DOI: 10.1101/Gad.1182504  0.307
2004 Kenney AM, Widlund HR, Rowitch DH. Hedgehog and PI-3 kinase signaling converge on Nmyc1 to promote cell cycle progression in cerebellar neuronal precursors Development. 131: 217-228. PMID 14660435 DOI: 10.1242/dev.00891  0.362
2003 Sun T, Dong H, Wu L, Kane M, Rowitch DH, Stiles CD. Cross-repressive interaction of the Olig2 and Nkx2.2 transcription factors in developing neural tube associated with formation of a specific physical complex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9547-56. PMID 14573534 DOI: 10.1523/Jneurosci.23-29-09547.2003  0.325
2003 Kim JY, Nelson AL, Algon SA, Graves O, Sturla LM, Goumnerova LC, Rowitch DH, Segal RA, Pomeroy SL. Medulloblastoma tumorigenesis diverges from cerebellar granule cell differentiation in patched heterozygous mice. Developmental Biology. 263: 50-66. PMID 14568546 DOI: 10.1016/S0012-1606(03)00434-2  0.399
2003 Mori-Akiyama Y, Akiyama H, Rowitch DH, De Crombrugghe B. Sox9 is required for determination of the chondrogenic cell lineage in the cranial neural crest Proceedings of the National Academy of Sciences of the United States of America. 100: 9360-9365. PMID 12878728 DOI: 10.1073/Pnas.1631288100  0.369
2003 Ligon KL, Echelard Y, Assimacopoulos S, Danielian PS, Kaing S, Grove EA, McMahon AP, Rowitch DH. Loss of Emx2 function leads to ectopic expression of Wnt1 in the developing telencephalon and cortical dysplasia. Development (Cambridge, England). 130: 2275-87. PMID 12668639 DOI: 10.1242/Dev.00421  0.596
2003 Kenney AM, Cole MD, Rowitch DH. Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors. Development (Cambridge, England). 130: 15-28. PMID 12441288 DOI: 10.1242/dev.00182  0.417
2002 Rowitch DH, Lu QR, Kessaris N, Richardson WD. An 'oligarchy' rules neural development. Trends in Neurosciences. 25: 417-22. PMID 12127759 DOI: 10.1016/S0166-2236(02)02201-4  0.41
2002 Bachoo RM, Maher EA, Ligon KL, Sharpless NE, Chan SS, You MJ, Tang Y, DeFrances J, Stover E, Weissleder R, Rowitch DH, Louis DN, DePinho RA. Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis. Cancer Cell. 1: 269-77. PMID 12086863 DOI: 10.1016/S1535-6108(02)00046-6  0.356
2002 Zhao Q, Kho A, Kenney AM, Yuk DI, Kohane I, Rowitch DH. Identification of genes expressed with temporal-spatial restriction to developing cerebellar neuron precursors by a functional genomic approach Proceedings of the National Academy of Sciences of the United States of America. 99: 5704-5709. PMID 11960025 DOI: 10.1073/Pnas.082092399  0.384
2002 Lu QR, Sun T, Zhu Z, Ma N, Garcia M, Stiles CD, Rowitch DH. Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection. Cell. 109: 75-86. PMID 11955448 DOI: 10.1016/S0092-8674(02)00678-5  0.453
2002 Heanue TA, Davis RJ, Rowitch DH, Kispert A, McMahon AP, Mardon G, Tabin CJ. Dach1, a vertebrate homologue of Drosophila dachshund, is expressed in the developing eye and ear of both chick and mouse and is regulated independently of Pax and Eya genes. Mechanisms of Development. 111: 75-87. PMID 11804780 DOI: 10.1016/S0925-4773(01)00611-6  0.52
2001 Alberta JA, Park SK, Mora J, Yuk D, Pawlitzky I, Iannarelli P, Vartanian T, Stiles CD, Rowitch DH. Sonic hedgehog is required during an early phase of oligodendrocyte development in mammalian brain. Molecular and Cellular Neurosciences. 18: 434-41. PMID 11640898 DOI: 10.1006/mcne.2001.1026  0.422
2001 Lu QR, Cai L, Rowitch D, Cepko CL, Stiles CD. Ectopic expression of Olig1 promotes oligodendrocyte formation and reduces neuronal survival in developing mouse cortex. Nature Neuroscience. 4: 973-4. PMID 11574831 DOI: 10.1038/nn718  0.415
2001 Sun T, Echelard Y, Lu R, Yuk DI, Kaing S, Stiles CD, Rowitch DH. Olig bHLH proteins interact with homeodomain proteins to regulate cell fate acquisition in progenitors of the ventral neural tube. Current Biology : Cb. 11: 1413-20. PMID 11566099 DOI: 10.1016/S0960-9822(01)00441-9  0.361
2001 Lu QR, Park JK, Noll E, Chan JA, Alberta J, Yuk D, Alzamora MG, Louis DN, Stiles CD, Rowitch DH, Black PM. Oligodendrocyte lineage genes (OLIG) as molecular markers for human glial brain tumors. Proceedings of the National Academy of Sciences of the United States of America. 98: 10851-6. PMID 11526205 DOI: 10.1073/Pnas.181340798  0.471
2001 Lagutin O, Zhu CC, Furuta Y, Rowitch DH, McMahon AP, Oliver G. Six3 promotes the formation of ectopic optic vesicle-like structures in mouse embryos. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 221: 342-9. PMID 11458394 DOI: 10.1002/Dvdy.1148  0.518
2001 Woodruff RH, Tekki-Kessaris N, Stiles CD, Rowitch DH, Richardson WD. Oligodendrocyte development in the spinal cord and telencephalon: common themes and new perspectives. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 19: 379-85. PMID 11378298 DOI: 10.1016/S0736-5748(00)00083-6  0.378
2001 Brault V, Moore R, Kutsch S, Ishibashi M, Rowitch DH, McMahon AP, Sommer L, Boussadia O, Kemler R. Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development. Development (Cambridge, England). 128: 1253-64. PMID 11262227  0.404
2001 Kuschert S, Rowitch DH, Haenig B, McMahon AP, Kispert A. Characterization of Pax-2 regulatory sequences that direct transgene expression in the Wolffian duct and its derivatives. Developmental Biology. 229: 128-40. PMID 11133159 DOI: 10.1006/Dbio.2000.9971  0.535
2000 Chai Y, Jiang X, Ito Y, Bringas P, Han J, Rowitch DH, Soriano P, McMahon AP, Sucov HM. Fate of the mammalian cranial neural crest during tooth and mandibular morphogenesis. Development (Cambridge, England). 127: 1671-9. PMID 10725243  0.503
2000 Jiang X, Rowitch DH, Soriano P, McMahon AP, Sucov HM. Fate of the mammalian cardiac neural crest. Development (Cambridge, England). 127: 1607-16. PMID 10725237  0.45
2000 Lu QR, Yuk D, Alberta JA, Zhu Z, Pawlitzky I, Chan J, McMahon AP, Stiles CD, Rowitch DH. Sonic hedgehog--regulated oligodendrocyte lineage genes encoding bHLH proteins in the mammalian central nervous system. Neuron. 25: 317-29. PMID 10719888 DOI: 10.1016/S0896-6273(00)80897-1  0.607
1999 Rowitch DH, Kispert A, McMahon AP. Pax-2 regulatory sequences that direct transgene expression in the developing neural plate and external granule cell layer of the cerebellum. Brain Research. Developmental Brain Research. 117: 99-108. PMID 10536237 DOI: 10.1016/S0165-3806(99)00104-2  0.567
1999 Rowitch DH, S-Jacques B, Lee SM, Flax JD, Snyder EY, McMahon AP. Sonic hedgehog regulates proliferation and inhibits differentiation of CNS precursor cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 8954-65. PMID 10516314 DOI: 10.1523/Jneurosci.19-20-08954.1999  0.587
1999 Rowitch DH, Danielian PS, McMahon AP, Zec N. Cystic malformation of the posterior cerebellar vermis in transgenic mice that ectopically express Engrailed-1, a homeodomain transcription factor. Teratology. 60: 22-8. PMID 10413335 DOI: 10.1002/(Sici)1096-9926(199907)60:1<22::Aid-Tera7>3.0.Co;2-6  0.555
1998 Danielian PS, Muccino D, Rowitch DH, Michael SK, McMahon AP. Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase. Current Biology : Cb. 8: 1323-6. PMID 9843687 DOI: 10.1016/S0960-9822(07)00562-3  0.524
1998 Rowitch DH, Echelard Y, Danielian PS, Gellner K, Brenner S, McMahon AP. Identification of an evolutionarily conserved 110 base-pair cis-acting regulatory sequence that governs Wnt-1 expression in the murine neural plate. Development (Cambridge, England). 125: 2735-46. PMID 9636087  0.404
1998 Rowitch DH, Danielian PS, McMahon AP, Zec N. Dandy-Walker Malformation in Transgenic Mice That Ectopically Express Engrailed-1, A Homeodomain Transcription Factor, in the Embryonic Brain • 302 Pediatric Research. 43: 54-54. DOI: 10.1203/00006450-199804001-00323  0.548
1997 Rowitch DH, Danielian PS, Lee SM, Echelard Y, McMahon AP. Cell interactions in patterning the mammalian midbrain. Cold Spring Harbor Symposia On Quantitative Biology. 62: 535-44. PMID 9598387 DOI: 10.1101/Sqb.1997.062.01.060  0.478
1997 Pepicelli CV, Kispert A, Rowitch DH, McMahon AP. GDNF induces branching and increased cell proliferation in the ureter of the mouse. Developmental Biology. 192: 193-8. PMID 9405108 DOI: 10.1006/Dbio.1997.8745  0.534
1996 Kispert A, Vainio S, Shen L, Rowitch DH, McMahon AP. Proteoglycans are required for maintenance of Wnt-11 expression in the ureter tips. Development (Cambridge, England). 122: 3627-37. PMID 8951078  0.471
1995 Iler N, Rowitch DH, Echelard Y, McMahon AP, Abate-Shen C. A single homeodomain binding site restricts spatial expression of Wnt-1 in the developing brain. Mechanisms of Development. 53: 87-96. PMID 8555114 DOI: 10.1016/0925-4773(95)00427-0  0.535
1995 Rowitch DH, McMahon AP. Pax-2 expression in the murine neural plate precedes and encompasses the expression domains of Wnt-1 and En-1. Mechanisms of Development. 52: 3-8. PMID 7577673 DOI: 10.1016/0925-4773(95)00380-J  0.541
1992 Molina-Garcia AD, Harding SE, Diaz FG, de la Torre JG, Rowitch D, Perham RN. Effect of coat protein mutations in bacteriophage fd studied by sedimentation analysis. Biophysical Journal. 63: 1293-8. PMID 19431854 DOI: 10.1016/S0006-3495(92)81725-3  0.504
1988 Rowitch DH, Hunter GJ, Perham RN. Variable electrostatic interaction between DNA and coat protein in filamentous bacteriophage assembly. Journal of Molecular Biology. 204: 663-74. PMID 3066910 DOI: 10.1016/0022-2836(88)90363-4  0.504
1987 Rowitch DH, Perham RN. Cloning and expression of the filamentous bacteriophage Pf1 major coat protein gene in Escherichia coli. Membrane protein processing and virus assembly. Journal of Molecular Biology. 195: 873-84. PMID 3309343 DOI: 10.1016/0022-2836(87)90491-8  0.504
1987 Hunter GJ, Rowitch DH, Perham RN. Interactions between DNA and coat protein in the structure and assembly of filamentous bacteriophage fd. Nature. 327: 252-4. PMID 3106834 DOI: 10.1038/327252a0  0.504
1986 Rowitch DH, Hunter GJ, Perham RN. DNA-protein interactions and DNA packaging in filamentous bacteriophages Biochemical Society Transactions. 14: 1168-1169. DOI: 10.1042/Bst0141168A  0.504
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