| Year |
Citation |
Score |
| 2014 |
Dorsch MP, Nemerovski CW, Ellingrod VL, Cowger JA, Dyke DB, Koelling TM, Wu AH, Aaronson KD, Simpson RU, Bleske BE. Vitamin D receptor genetics on extracellular matrix biomarkers and hemodynamics in systolic heart failure. Journal of Cardiovascular Pharmacology and Therapeutics. 19: 439-45. PMID 24500905 DOI: 10.1177/1074248413517747 |
0.525 |
|
| 2012 |
Kim SH, Chen G, King AN, Jeon CK, Christensen PJ, Zhao L, Simpson RU, Thomas DG, Giordano TJ, Brenner DE, Hollis B, Beer DG, Ramnath N. Characterization of vitamin D receptor (VDR) in lung adenocarcinoma. Lung Cancer (Amsterdam, Netherlands). 77: 265-71. PMID 22564539 DOI: 10.1016/J.Lungcan.2012.04.010 |
0.502 |
|
| 2012 |
Johnson LA, Sauder KL, Rodansky ES, Simpson RU, Higgins PD. CARD-024, a vitamin D analog, attenuates the pro-fibrotic response to substrate stiffness in colonic myofibroblasts. Experimental and Molecular Pathology. 93: 91-8. PMID 22542712 DOI: 10.1016/j.yexmp.2012.04.014 |
0.434 |
|
| 2012 |
Johnson L, Sauder K, Rodansky E, Simpson R. P060 CARD-024, a vitamin D analog, attenuates the pro-fibrotic response to TGFβ or substrate stiffness in colonic myofibroblasts Journal of Crohn's and Colitis. 6: S34-S35. DOI: 10.1016/S1873-9946(12)60081-6 |
0.353 |
|
| 2011 |
Simpson RU. Selective knockout of the vitamin d receptor in the heart results in cardiac hypertrophy: is the heart a drugable target for vitamin D receptor agonists? Circulation. 124: 1808-10. PMID 22025636 DOI: 10.1161/CIRCULATIONAHA.111.061234 |
0.555 |
|
| 2011 |
Chen G, Kim SH, King AN, Zhao L, Simpson RU, Christensen PJ, Wang Z, Thomas DG, Giordano TJ, Lin L, Brenner DE, Beer DG, Ramnath N. CYP24A1 is an independent prognostic marker of survival in patients with lung adenocarcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 817-26. PMID 21169243 DOI: 10.1158/1078-0432.Ccr-10-1789 |
0.37 |
|
| 2011 |
Ceglia L, Simpson RU. Vitamin D and skeletal muscle function Vitamin D. 2023-2041. DOI: 10.1016/B978-0-12-381978-9.10104-0 |
0.316 |
|
| 2010 |
Zhao G, Simpson RU. Interaction between vitamin D receptor with caveolin-3 and regulation by 1,25-dihydroxyvitamin D3 in adult rat cardiomyocytes. The Journal of Steroid Biochemistry and Molecular Biology. 121: 159-63. PMID 20304057 DOI: 10.1016/j.jsbmb.2010.03.055 |
0.55 |
|
| 2010 |
King AN, Beer DG, Christensen PJ, Simpson RU, Ramnath N. The vitamin D/CYP24A1 story in cancer. Anti-Cancer Agents in Medicinal Chemistry. 10: 213-24. PMID 20184548 DOI: 10.2174/1871520611009030213 |
0.482 |
|
| 2010 |
Scragg RK, Camargo CA, Simpson RU. Relation of serum 25-hydroxyvitamin D to heart rate and cardiac work (from the National Health and Nutrition Examination Surveys). The American Journal of Cardiology. 105: 122-8. PMID 20102903 DOI: 10.1016/j.amjcard.2009.08.661 |
0.474 |
|
| 2010 |
Zhao G, Simpson RU. Membrane localization, Caveolin-3 association and rapid actions of vitamin D receptor in cardiac myocytes. Steroids. 75: 555-9. PMID 20015453 DOI: 10.1016/j.steroids.2009.12.001 |
0.539 |
|
| 2010 |
Przybylski R, McCune S, Hollis B, Simpson RU. Vitamin D deficiency in the spontaneously hypertensive heart failure [SHHF] prone rat. Nutrition, Metabolism, and Cardiovascular Diseases : Nmcd. 20: 641-6. PMID 19836216 DOI: 10.1016/j.numecd.2009.07.009 |
0.543 |
|
| 2009 |
Wilke RA, Simpson RU, Mukesh BN, Bhupathi SV, Dart RA, Ghebranious NR, McCarty CA. Genetic variation in CYP27B1 is associated with congestive heart failure in patients with hypertension. Pharmacogenomics. 10: 1789-97. PMID 19891555 DOI: 10.2217/pgs.09.101 |
0.364 |
|
| 2009 |
Nemerovski CW, Dorsch MP, Simpson RU, Bone HG, Aaronson KD, Bleske BE. Vitamin D and cardiovascular disease. Pharmacotherapy. 29: 691-708. PMID 19476421 DOI: 10.1592/phco.29.6.691 |
0.532 |
|
| 2009 |
Weber KT, Weglicki WB, Simpson RU. Macro- and micronutrient dyshomeostasis in the adverse structural remodelling of myocardium. Cardiovascular Research. 81: 500-8. PMID 18835843 DOI: 10.1093/cvr/cvn261 |
0.366 |
|
| 2008 |
Mancuso P, Rahman A, Hershey SD, Dandu L, Nibbelink KA, Simpson RU. 1,25-Dihydroxyvitamin-D3 treatment reduces cardiac hypertrophy and left ventricular diameter in spontaneously hypertensive heart failure-prone (cp/+) rats independent of changes in serum leptin. Journal of Cardiovascular Pharmacology. 51: 559-64. PMID 18496147 DOI: 10.1097/Fjc.0B013E3181761906 |
0.531 |
|
| 2008 |
Weber KT, Simpson RU, Carbone LD. Vitamin D and calcium dyshomoeostasis-associated heart failure. Heart (British Cardiac Society). 94: 540-1. PMID 18413299 DOI: 10.1136/hrt.2007.126359 |
0.431 |
|
| 2008 |
Tishkoff DX, Nibbelink KA, Holmberg KH, Dandu L, Simpson RU. Functional vitamin D receptor (VDR) in the t-tubules of cardiac myocytes: VDR knockout cardiomyocyte contractility. Endocrinology. 149: 558-64. PMID 17974622 DOI: 10.1210/en.2007-0805 |
0.641 |
|
| 2007 |
Nibbelink KA, Tishkoff DX, Hershey SD, Rahman A, Simpson RU. 1,25(OH)2-vitamin D3 actions on cell proliferation, size, gene expression, and receptor localization, in the HL-1 cardiac myocyte. The Journal of Steroid Biochemistry and Molecular Biology. 103: 533-7. PMID 17276054 DOI: 10.1016/j.jsbmb.2006.12.099 |
0.571 |
|
| 2007 |
Simpson RU, Hershey SH, Nibbelink KA. Characterization of heart size and blood pressure in the vitamin D receptor knockout mouse. The Journal of Steroid Biochemistry and Molecular Biology. 103: 521-4. PMID 17275289 DOI: 10.1016/j.jsbmb.2006.12.098 |
0.389 |
|
| 2007 |
Rahman A, Hershey S, Ahmed S, Nibbelink K, Simpson RU. Heart extracellular matrix gene expression profile in the vitamin D receptor knockout mice. The Journal of Steroid Biochemistry and Molecular Biology. 103: 416-9. PMID 17275288 DOI: 10.1016/j.jsbmb.2006.12.081 |
0.446 |
|
| 2006 |
Green JJ, Robinson DA, Wilson GE, Simpson RU, Westfall MV. Calcitriol modulation of cardiac contractile performance via protein kinase C. Journal of Molecular and Cellular Cardiology. 41: 350-9. PMID 16815434 DOI: 10.1016/j.yjmcc.2006.05.019 |
0.398 |
|
| 2001 |
Pan Q, Simpson RU. Antisense knockout of HOXB4 blocks 1,25-dihydroxyvitamin D3 inhibition of c-myc expression. The Journal of Endocrinology. 169: 153-9. PMID 11250656 DOI: 10.1677/joe.0.1690153 |
0.474 |
|
| 1999 |
Pan Q, Simpson RU. c-myc intron element-binding proteins are required for 1, 25-dihydroxyvitamin D3 regulation of c-myc during HL-60 cell differentiation and the involvement of HOXB4. The Journal of Biological Chemistry. 274: 8437-44. PMID 10085075 DOI: 10.1074/jbc.274.13.8437 |
0.478 |
|
| 1998 |
Simpson RU, O'Connell TD, Pan Q, Newhouse J, Somerman MJ. Antisense oligonucleotides targeted against protein kinase Cbeta and CbetaII block 1,25-(OH)2D3-induced differentiation. The Journal of Biological Chemistry. 273: 19587-91. PMID 9677384 DOI: 10.1074/Jbc.273.31.19587 |
0.517 |
|
| 1997 |
Pan Q, Granger J, O'Connell TD, Somerman MJ, Simpson RU. Promotion of HL-60 cell differentiation by 1,25-dihydroxyvitamin D3 regulation of protein kinase C levels and activity. Biochemical Pharmacology. 54: 909-15. PMID 9354591 DOI: 10.1016/S0006-2952(97)00286-4 |
0.493 |
|
| 1997 |
Atkins KB, Simpson RU, Somerman MJ. Stimulation of osteopontin mRNA expression in HL-60 cells is independent of differentiation. Archives of Biochemistry and Biophysics. 343: 157-63. PMID 9224725 DOI: 10.1006/Abbi.1997.0151 |
0.306 |
|
| 1997 |
O'Connell TD, Berry JE, Jarvis AK, Somerman MJ, Simpson RU. 1,25-Dihydroxyvitamin D3 regulation of cardiac myocyte proliferation and hypertrophy. The American Journal of Physiology. 272: H1751-8. PMID 9139959 DOI: 10.1152/Ajpheart.1997.272.4.H1751 |
0.559 |
|
| 1997 |
O'Connell TD, Berry JE, Jarvis AK, Somerman MJ, Simpson RU. 1, 25-Dihydroxyvitamin D3 regulation of cardiac myocyte proliferation and hypertrophy American Journal of Physiology. 272: H1759-H1769. |
0.385 |
|
| 1996 |
O'Connell TD, Simpson RU. Immunochemical identification of the 1,25-dihydroxyvitamin D3 receptor protein in human heart. Cell Biology International. 20: 621-4. PMID 8948124 DOI: 10.1006/cbir.1996.0081 |
0.531 |
|
| 1996 |
Pan Q, Martell RE, O'Connell TD, Simpson RU. 1,25-Dihydroxyvitamin D3-regulated binding of nuclear proteins to a c-myc intron element. Endocrinology. 137: 4154-60. PMID 8828471 DOI: 10.1210/endo.137.10.8828471 |
0.44 |
|
| 1995 |
Somerman MJ, Berry JE, Khalkhali-Ellis Z, Osdoby P, Simpson RU. Enhanced expression of alpha v integrin subunit and osteopontin during differentiation of HL-60 cells along the monocytic pathway. Experimental Cell Research. 216: 335-41. PMID 7843278 DOI: 10.1006/Excr.1995.1042 |
0.307 |
|
| 1995 |
O'Connell TD, Giacherio DA, Jarvis AK, Simpson RU. Inhibition of cardiac myocyte maturation by 1,25-dihydroxyvitamin D3. Endocrinology. 136: 482-8. PMID 7835280 DOI: 10.1210/endo.136.2.7835280 |
0.538 |
|
| 1995 |
O'Connell TD, Simpson RU. 1,25-Dihydroxyvitamin D3 regulation of myocardial growth and c-myc levels in the rat heart. Biochemical and Biophysical Research Communications. 213: 59-65. PMID 7639762 DOI: 10.1006/bbrc.1995.2098 |
0.545 |
|
| 1994 |
O'Connell TD, Weishaar RE, Simpson RU. Regulation of myosin isozyme expression by vitamin D3 deficiency and 1,25-dihydroxyvitamin D3 in the rat heart. Endocrinology. 134: 899-905. PMID 8299585 DOI: 10.1210/endo.134.2.8299585 |
0.534 |
|
| 1994 |
Coffey MJ, Wilcoxen SE, Phare SM, Simpson RU, Gyetko MR, Peters-Golden M. Reduced 5-lipoxygenase metabolism of arachidonic acid in macrophages rrom 1,25-dihydroxyvitamin D3-deficient rats. Prostaglandins. 48: 313-29. PMID 7855310 DOI: 10.1016/0090-6980(94)90031-0 |
0.505 |
|
| 1991 |
Kole KL, Gyetko MR, Simpson RU, Sitrin RG. Calcitriol-mediated modulation of urokinase-type plasminogen activator and plasminogen activator inhibitor-2. Biochemical Pharmacology. 41: 585-91. PMID 1900005 DOI: 10.1016/0006-2952(91)90631-E |
0.31 |
|
| 1990 |
Weishaar RE, Kim SN, Saunders DE, Simpson RU. Involvement of vitamin D3 with cardiovascular function. III. Effects on physical and morphological properties. The American Journal of Physiology. 258: E134-42. PMID 2154115 |
0.451 |
|
| 1989 |
Strawn LM, Martell RE, Simpson RU, Leach KL, Counsell RE. Synthesis and evaluation of iodinated analogues of diacylglycerols as potential probes for protein kinase C. Journal of Medicinal Chemistry. 32: 643-8. PMID 2918512 DOI: 10.1021/Jm00123A024 |
0.305 |
|
| 1989 |
Patel S, Simpson RU, Hsu CH. Effect of vitamin D metabolites on calcitriol metabolism in experimental renal failure. Kidney International. 36: 234-9. PMID 2789310 DOI: 10.1038/Ki.1989.185 |
0.382 |
|
| 1989 |
Simpson RU, Hsu T, Wendt MD, Taylor JM. 1,25-Dihydroxyvitamin D3 regulation of c-myc protooncogene transcription. Possible involvement of protein kinase C. The Journal of Biological Chemistry. 264: 19710-5. PMID 2684961 |
0.425 |
|
| 1989 |
Weishaar RE, Simpson RU. The involvement of the endocrine system in regulating cardiovascular function: emphasis on vitamin D3. Endocrine Reviews. 10: 351-65. PMID 2550215 DOI: 10.1210/edrv-10-3-351 |
0.476 |
|
| 1988 |
Martell RE, Simpson RU, Hsu T. Effects of protein kinase inhibitors 1(5-isoquinolinesulfonyl)-2-methylpiperazine dihydrochloride (H-7) and N-[2-guanidinoethyl]-5-isoquinolinesulfonamide hydrochloride (HA1004) on calcitriol-induced differentiation of HL-60 cells. Biochemical Pharmacology. 37: 635-40. PMID 3422561 DOI: 10.1016/0006-2952(88)90136-0 |
0.32 |
|
| 1988 |
Simpson RU, Weishaar RE. Involvement of 1,25-dihydroxyvitamin D3 in regulating myocardial calcium metabolism: physiological and pathological actions. Cell Calcium. 9: 285-92. PMID 3066493 DOI: 10.1016/0143-4160(88)90009-7 |
0.552 |
|
| 1987 |
Martell RE, Simpson RU, Taylor JM. 1,25-Dihydroxyvitamin D3 regulation of phorbol ester receptors in HL-60 leukemia cells. The Journal of Biological Chemistry. 262: 5570-5. PMID 3471756 |
0.318 |
|
| 1987 |
Zile MH, Cullum ME, Simpson RU, Barua AB, Swartz DA. Induction of differentiation of human promyelocytic leukemia cell line HL-60 by retinoyl glucuronide, a biologically active metabolite of vitamin A. Proceedings of the National Academy of Sciences of the United States of America. 84: 2208-12. PMID 3470785 DOI: 10.1073/pnas.84.8.2208 |
0.318 |
|
| 1987 |
Weishaar RE, Simpson RU. Vitamin D3 and cardiovascular function in rats. The Journal of Clinical Investigation. 79: 1706-12. PMID 3034981 DOI: 10.1172/JCI113010 |
0.436 |
|
| 1987 |
Weishaar RE, Simpson RU. Involvement of vitamin D3 with cardiovascular function. II. Direct and indirect effects. The American Journal of Physiology. 253: E675-83. PMID 2827502 |
0.445 |
|
| 1986 |
Simpson RU, Arnold AJ. Calcium antagonizes 1,25-dihydroxyvitamin D3 inhibition of breast cancer cell proliferation. Endocrinology. 119: 2284-9. PMID 3464413 DOI: 10.1210/endo-119-5-2284 |
0.392 |
|
| 1986 |
Simpson RU, Weishaar R. Newly discovered activities for calcitriol (1,25-dihydroxyvitamin D3): implications for future pharmacological use. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 4: 65-70. PMID 3024636 DOI: 10.1002/bies.950040206 |
0.435 |
|
| 1986 |
Thomas GA, Simpson RU. High performance liquid chromatography analysis of 1,25-dihydroxyvitamin D3 receptor in malignant cells. Correlation of effects on cell proliferation and receptor concentration. Cancer Biochemistry Biophysics. 8: 221-34. PMID 3017543 |
0.389 |
|
| 1985 |
Simpson RU, Thomas GA, Arnold AJ. Identification of 1,25-dihydroxyvitamin D3 receptors and activities in muscle. The Journal of Biological Chemistry. 260: 8882-91. PMID 2991224 |
0.425 |
|
| 1984 |
Simpson RU, Wichmann JK, Paaren HE, Schnoes HK, DeLuca HF. Metabolism of 25-hydroxyvitamin D3 by rat kidney cells in culture: isolation and identification of cis- and trans-19-nor-10-oxo-25-hydroxyvitamin D3. Archives of Biochemistry and Biophysics. 230: 21-9. PMID 6712232 DOI: 10.1016/0003-9861(84)90082-1 |
0.407 |
|
| 1984 |
Simpson RU, Thomas GA, Diard L. 1,25-Dihydroxyvitamin D3 (1,25(OH)2D3) receptors in human leukemia cells Federation Proceedings. 43: no. 1177. |
0.403 |
|
| 1983 |
Massaro ER, Simpson RU, DeLuca HF. Quantitation of endogenously occupied and unoccupied binding sites for 1,25-dihydroxyvitamin D3 in rat intestine. Proceedings of the National Academy of Sciences of the United States of America. 80: 2549-53. PMID 6302695 DOI: 10.1073/Pnas.80.9.2549 |
0.388 |
|
| 1983 |
Massaro ER, Simpson RU, DeLuca HF. Glucocorticoids and appearance of 1,25-dihydroxyvitamin D3 receptor in rat intestine. The American Journal of Physiology. 244: E230-5. PMID 6299113 DOI: 10.1152/Ajpendo.1983.244.3.E230 |
0.368 |
|
| 1982 |
Simpson RU, Wichmann JK, Paaren HE. Metabolism of 25-hydroxyvitamin D. by rat kidney cells in culture: Isolation and identification of 19-nor-10-oxo-25-hydroxyvitamin D3 Federation Proceedings. 41: 6937. |
0.373 |
|
| 1982 |
Massaro ER, Simpson RU, DeLuca HF. Quantitation of endogenously occupied and unoccupied receptors for 1,25-(OH)2D3 in rat duodenum Federation Proceedings. 41: 7729. |
0.346 |
|
| 1981 |
Franceschi RT, Simpson RU, DeLuca HF. Binding proteins for vitamin D metabolites: serum carriers and intracellular receptors. Archives of Biochemistry and Biophysics. 210: 1-13. PMID 6271063 DOI: 10.1016/0003-9861(81)90157-0 |
0.373 |
|
| 1980 |
Simpson RU, DeLuca HF. Characterization of a receptor-like protein for 1,25-dihydroxyvitamin D3 in rat skin. Proceedings of the National Academy of Sciences of the United States of America. 77: 5822-6. PMID 6255467 DOI: 10.1073/Pnas.77.10.5822 |
0.401 |
|
| 1980 |
Simpson RU, Franceschi RT, DeLuca HF. Characterization of a specific, high affinity binding macromolecule for 1 alpha, 25-dihydroxyvitamin D3 in cultured chick kidney cells. The Journal of Biological Chemistry. 255: 10160-6. PMID 6253464 |
0.426 |
|
| 1980 |
Simpson RU, Franceschi RT, DeLuca HF. Characterization of specific cytosol 1,25-dihydroxyvitamin D3 binding protein from chick kidney cells in culture Federation Proceedings. 39: 3578. |
0.324 |
|
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