Cecilia Canessa - Publications

Affiliations: 
Yale University School of Medicine, New Haven, CT 
Area:
ASIC channels
Website:
http://www.med.yale.edu/cmphysiol/faculty/facultypages/canessa.html

80 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 González-Fernández R, Ávila J, Arteaga MF, Canessa CM, Martín-Vasallo P. The neuronal-specific SGK1.1 (SGK1_v2) kinase as a transcriptional modulator of BAG4, Brox, and PPP1CB genes expression. International Journal of Molecular Sciences. 16: 7462-77. PMID 25849655 DOI: 10.3390/ijms16047462  1
2014 Li T, Yang Y, Canessa CM. A method for activation of endogenous acid-sensing ion channel 1a (ASIC1a) in the nervous system with high spatial and temporal precision. The Journal of Biological Chemistry. 289: 15441-8. PMID 24727474 DOI: 10.1074/jbc.M114.550012  1
2013 Hernández-Díaz I, Giraldez T, Morales S, Hernandez G, Salido E, Canessa CM, Alvarez de la Rosa D. Heterogeneous nuclear ribonucleoprotein A2/B1 is a tissue-specific aldosterone target gene with prominent induction in the rat distal colon. American Journal of Physiology. Gastrointestinal and Liver Physiology. 304: G122-31. PMID 23139218 DOI: 10.1152/ajpgi.00130.2012  1
2012 Li T, Yang Y, Canessa CM. Impact of recovery from desensitization on acid-sensing ion channel-1a (ASIC1a) current and response to high frequency stimulation. The Journal of Biological Chemistry. 287: 40680-9. PMID 23048040 DOI: 10.1074/jbc.M112.418400  1
2011 Li T, Yang Y, Canessa CM. Outlines of the pore in open and closed conformations describe the gating mechanism of ASIC1. Nature Communications. 2: 399. PMID 21772270 DOI: 10.1038/ncomms1409  1
2011 Li T, Yang Y, Canessa CM. Asp433 in the closing gate of ASIC1 determines stability of the open state without changing properties of the selectivity filter or Ca2+ block. The Journal of General Physiology. 137: 289-97. PMID 21357733 DOI: 10.1085/jgp.201010576  1
2010 Li T, Yang Y, Canessa CM. Asn415 in the beta11-beta12 linker decreases proton-dependent desensitization of ASIC1. The Journal of Biological Chemistry. 285: 31285-91. PMID 20675379 DOI: 10.1074/jbc.M110.160382  1
2010 Li T, Yang Y, Canessa CM. Leu85 in the beta1-beta2 linker of ASIC1 slows activation and decreases the apparent proton affinity by stabilizing a closed conformation. The Journal of Biological Chemistry. 285: 22706-12. PMID 20479002 DOI: 10.1074/jbc.M110.134114  1
2010 Li T, Yang Y, Canessa CM. Two residues in the extracellular domain convert a nonfunctional ASIC1 into a proton-activated channel. American Journal of Physiology. Cell Physiology. 299: C66-73. PMID 20427715 DOI: 10.1152/ajpcell.00100.2010  1
2009 Li T, Yang Y, Canessa CM. Interaction of the aromatics Tyr-72/Trp-288 in the interface of the extracellular and transmembrane domains is essential for proton gating of acid-sensing ion channels. The Journal of Biological Chemistry. 284: 4689-94. PMID 19074149 DOI: 10.1074/jbc.M805302200  1
2009 Mobasheri A, Cathro HP, German A, Marples D, Martín-vasallo P, Canessa CM. Applications of Tissue Microarrays in Renal Physiology and Pathology Renal and Urinary Proteomics: Methods and Protocols. 97-118. DOI: 10.1002/9783527628612.ch8  1
2008 Arteaga MF, Coric T, Straub C, Canessa CM. A brain-specific SGK1 splice isoform regulates expression of ASIC1 in neurons. Proceedings of the National Academy of Sciences of the United States of America. 105: 4459-64. PMID 18334630 DOI: 10.1073/pnas.0800958105  1
2008 Coric T, Passamaneck YJ, Zhang P, Di Gregorio A, Canessa CM. Simple chordates exhibit a proton-independent function of acid-sensing ion channels. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 1914-23. PMID 18211956 DOI: 10.1096/fj.07-100313  1
2007 Canessa CM. Structural biology: unexpected opening. Nature. 449: 293-4. PMID 17882209 DOI: 10.1038/449293a  1
2007 Arteaga MF, Alvarez de la Rosa D, Alvarez JA, Canessa CM. Multiple translational isoforms give functional specificity to serum- and glucocorticoid-induced kinase 1. Molecular Biology of the Cell. 18: 2072-80. PMID 17377066 DOI: 10.1091/mbc.E06-10-0968  1
2006 Arteaga MF, Wang L, Ravid T, Hochstrasser M, Canessa CM. An amphipathic helix targets serum and glucocorticoid-induced kinase 1 to the endoplasmic reticulum-associated ubiquitin-conjugation machinery. Proceedings of the National Academy of Sciences of the United States of America. 103: 11178-83. PMID 16847254 DOI: 10.1073/pnas.0604816103  1
2006 Zhang P, Sigworth FJ, Canessa CM. Gating of acid-sensitive ion channel-1: release of Ca2+ block vs. allosteric mechanism. The Journal of General Physiology. 127: 109-17. PMID 16418400 DOI: 10.1085/jgp.200509396  1
2006 Leng Q, Kahle KT, Rinehart J, MacGregor GG, Wilson FH, Canessa CM, Lifton RP, Hebert SC. WNK3, a kinase related to genes mutated in hereditary hypertension with hyperkalaemia, regulates the K+ channel ROMK1 (Kir1.1). The Journal of Physiology. 571: 275-86. PMID 16357011 DOI: 10.1113/jphysiol.2005.102202  1
2006 Alvarez de la Rosa D, Gimenez I, Forbush B, Canessa CM. SGK1 activates Na+-K+-ATPase in amphibian renal epithelial cells. American Journal of Physiology. Cell Physiology. 290: C492-8. PMID 16192298 DOI: 10.1152/ajpcell.00556.2004  1
2005 Todorović N, Corić T, Zhang P, Canessa C. Effects of extracellular calcium on fASIC1 currents. Annals of the New York Academy of Sciences. 1048: 331-6. PMID 16154945 DOI: 10.1196/annals.1342.030  1
2005 Coric T, Zheng D, Gerstein M, Canessa CM. Proton sensitivity of ASIC1 appeared with the rise of fishes by changes of residues in the region that follows TM1 in the ectodomain of the channel. The Journal of Physiology. 568: 725-35. PMID 16002453 DOI: 10.1113/jphysiol.2005.087734  1
2005 Arteaga MF, Canessa CM. Functional specificity of Sgk1 and Akt1 on ENaC activity. American Journal of Physiology. Renal Physiology. 289: F90-6. PMID 15951481 DOI: 10.1152/ajprenal.00390.2004  1
2005 Roux J, Kawakatsu H, Gartland B, Pespeni M, Sheppard D, Matthay MA, Canessa CM, Pittet JF. Interleukin-1beta decreases expression of the epithelial sodium channel alpha-subunit in alveolar epithelial cells via a p38 MAPK-dependent signaling pathway. The Journal of Biological Chemistry. 280: 18579-89. PMID 15755725 DOI: 10.1074/jbc.M410561200  1
2005 Zhang YH, Alvarez de la Rosa D, Canessa CM, Hayslett JP. Insulin-induced phosphorylation of ENaC correlates with increased sodium channel function in A6 cells. American Journal of Physiology. Cell Physiology. 288: C141-7. PMID 15355850 DOI: 10.1152/ajpcell.00343.2004  1
2004 Alvarez de la Rosa D, Paunescu TG, Els WJ, Helman SI, Canessa CM. Mechanisms of regulation of epithelial sodium channel by SGK1 in A6 cells. The Journal of General Physiology. 124: 395-407. PMID 15452200 DOI: 10.1085/jgp.200409120  1
2004 Mobasheri A, Critchlow K, Clegg PD, Carter SD, Canessa CM. Chronic equine laminitis is characterised by loss of GLUT1, GLUT4 and ENaC positive laminar keratinocytes. Equine Veterinary Journal. 36: 248-54. PMID 15147133  1
2004 Coric T, Hernandez N, Alvarez de la Rosa D, Shao D, Wang T, Canessa CM. Expression of ENaC and serum- and glucocorticoid-induced kinase 1 in the rat intestinal epithelium. American Journal of Physiology. Gastrointestinal and Liver Physiology. 286: G663-70. PMID 14630642 DOI: 10.1152/ajpgi.00364.2003  1
2003 Coric T, Zhang P, Todorovic N, Canessa CM. The extracellular domain determines the kinetics of desensitization in acid-sensitive ion channel 1. The Journal of Biological Chemistry. 278: 45240-7. PMID 12947112 DOI: 10.1074/jbc.M304441200  1
2003 Frank J, Roux J, Kawakatsu H, Su G, Dagenais A, Berthiaume Y, Howard M, Canessa CM, Fang X, Sheppard D, Matthay MA, Pittet JF. Transforming growth factor-beta1 decreases expression of the epithelial sodium channel alphaENaC and alveolar epithelial vectorial sodium and fluid transport via an ERK1/2-dependent mechanism. The Journal of Biological Chemistry. 278: 43939-50. PMID 12930837 DOI: 10.1074/jbc.M304882200  1
2003 Alvarez de la Rosa D, Coric T, Todorovic N, Shao D, Wang T, Canessa CM. Distribution and regulation of expression of serum- and glucocorticoid-induced kinase-1 in the rat kidney. The Journal of Physiology. 551: 455-66. PMID 12816971 DOI: 10.1113/jphysiol.2003.042903  1
2003 Alvarez de la Rosa D, Krueger SR, Kolar A, Shao D, Fitzsimonds RM, Canessa CM. Distribution, subcellular localization and ontogeny of ASIC1 in the mammalian central nervous system. The Journal of Physiology. 546: 77-87. PMID 12509480 DOI: 10.1113/jphysiol.2002.030692  1
2003 Alvarez de la Rosa D, Canessa CM. Role of SGK in hormonal regulation of epithelial sodium channel in A6 cells. American Journal of Physiology. Cell Physiology. 284: C404-14. PMID 12388075 DOI: 10.1152/ajpcell.00398.2002  1
2002 Zhang P, Canessa CM. Single channel properties of rat acid-sensitive ion channel-1alpha, -2a, and -3 expressed in Xenopus oocytes. The Journal of General Physiology. 120: 553-66. PMID 12356856 DOI: 10.1085/jgp.20028574  1
2002 Alvarez de la Rosa D, Li H, Canessa CM. Effects of aldosterone on biosynthesis, traffic, and functional expression of epithelial sodium channels in A6 cells. The Journal of General Physiology. 119: 427-42. PMID 11981022 DOI: 10.1085/jgp.20028559  1
2002 Alvarez de la Rosa D, Zhang P, Shao D, White F, Canessa CM. Functional implications of the localization and activity of acid-sensitive channels in rat peripheral nervous system. Proceedings of the National Academy of Sciences of the United States of America. 99: 2326-31. PMID 11842212 DOI: 10.1073/pnas.042688199  1
2001 Zhang P, Canessa CM. Single-channel properties of recombinant acid-sensitive ion channels formed by the subunits ASIC2 and ASIC3 from dorsal root ganglion neurons expressed in Xenopus oocytes. The Journal of General Physiology. 117: 563-72. PMID 11382806 DOI: 10.1085/jgp.117.6.563  1
2000 Gupta SS, Canessa CM. Heterologous expression of a mammalian epithelial sodium channel in yeast. Febs Letters. 481: 77-80. PMID 10984619 DOI: 10.1016/S0014-5793(00)01977-3  1
2000 Alvarez de la Rosa D, Canessa CM, Fyfe GK, Zhang P. Structure and regulation of amiloride-sensitive sodium channels. Annual Review of Physiology. 62: 573-94. PMID 10845103 DOI: 10.1146/annurev.physiol.62.1.573  1
1999 Alvarez de la Rosa D, Zhang P, Náray-Fejes-Tóth A, Fejes-Tóth G, Canessa CM. The serum and glucocorticoid kinase sgk increases the abundance of epithelial sodium channels in the plasma membrane of Xenopus oocytes. The Journal of Biological Chemistry. 274: 37834-9. PMID 10608847 DOI: 10.1074/jbc.274.53.37834  1
1999 Fyfe GK, Zhang P, Canessa CM. The second hydrophobic domain contributes to the kinetic properties of epithelial sodium channels. The Journal of Biological Chemistry. 274: 36415-21. PMID 10593937 DOI: 10.1074/jbc.274.51.36415  1
1999 Zhang P, Fyfe GK, Grichtchenko II, Canessa CM. Inhibition of alphabeta epithelial sodium channels by external protons indicates that the second hydrophobic domain contains structural elements for closing the pore. Biophysical Journal. 77: 3043-51. PMID 10585926 DOI: 10.1016/S0006-3495(99)77135-3  0.4
1999 Gabús R, Magariños A, Zamora M, De Lisa E, Landoni AI, Martínez G, Canessa C, Giordano H, Bodega E. Evaluation of hematopoietic progenitors in hematopoietic progenitor cell transplants. CD34+ dose effect in marrow recovery. Retrospective analysis in 38 patients. Hematology and Cell Therapy. 41: 171-7. PMID 10543373 DOI: 10.1007/s00282-999-0171-y  1
1999 Trujillo E, Alvarez de la Rosa D, Mobasheri A, González T, Canessa CM, Martín-Vasallo P. Sodium transport systems in human chondrocytes. II. Expression of ENaC, Na+/K+/2Cl- cotransporter and Na+/H+ exchangers in healthy and arthritic chondrocytes. Histology and Histopathology. 14: 1023-31. PMID 10506918  1
1999 Náray-Fejes-Tóth A, Canessa C, Cleaveland ES, Aldrich G, Fejes-Tóth G. sgk is an aldosterone-induced kinase in the renal collecting duct. Effects on epithelial na+ channels. The Journal of Biological Chemistry. 274: 16973-8. PMID 10358046 DOI: 10.1074/jbc.274.24.16973  1
1999 Zhang P, Fyfe GK, Grichtchenko II, Canessa CM. Inhibition of αβ epithelial sodium channels by external protons indicates that the second hydrophobic domain contains structural elements for closing the pore Biophysical Journal. 77: 3043-3051.  1
1998 Valentijn JA, Fyfe GK, Canessa CM. Biosynthesis and processing of epithelial sodium channels in Xenopus oocytes. The Journal of Biological Chemistry. 273: 30344-51. PMID 9804797 DOI: 10.1074/jbc.273.46.30344  1
1998 Fyfe GK, Canessa CM. Subunit composition determines the single channel kinetics of the epithelial sodium channel. The Journal of General Physiology. 112: 423-32. PMID 9758861 DOI: 10.1085/jgp.112.4.423  1
1998 Fyfe GK, Quinn A, Canessa CM. Structure and function of the Mec-ENaC family of ion channels. Seminars in Nephrology. 18: 138-51. PMID 9541269  1
1998 Shimkets RA, Lifton R, Canessa CM. In vivo phosphorylation of the epithelial sodium channel. Proceedings of the National Academy of Sciences of the United States of America. 95: 3301-5. PMID 9501257 DOI: 10.1073/pnas.95.6.3301  1
1997 Shimkets RA, Lifton RP, Canessa CM. The activity of the epithelial sodium channel is regulated by clathrin-mediated endocytosis. The Journal of Biological Chemistry. 272: 25537-41. PMID 9325269 DOI: 10.1074/jbc.272.41.25537  1
1997 McNicholas CM, Canessa CM. Diversity of channels generated by different combinations of epithelial sodium channel subunits. The Journal of General Physiology. 109: 681-92. PMID 9222895 DOI: 10.1085/jgp.109.6.681  1
1997 Farman N, Talbot CR, Boucher R, Fay M, Canessa C, Rossier B, Bonvalet JP. Noncoordinated expression of alpha-, beta-, and gamma-subunit mRNAs of epithelial Na+ channel along rat respiratory tract. The American Journal of Physiology. 272: C131-41. PMID 9038819  1
1996 Canessa CM. What is new about the structure of the epithelial Na+ channel? News in Physiological Sciences. 11: 195-201.  1
1995 Shimkets RA, Warnock DG, Bositis CM, Nelson-Willia C, Hansson JH, Schambelan M, Gill JR, Ulick S, Milora RV, Findling JW, Canessa CM, Rossier BC, Lifton RP, Corvol P. Liddle’s syndrome: Heritable human hypertension caused by mutations in the ß subnit of the epithelial sodium channel Journal of Endocrinological Investigation. 18: 592-594. PMID 9221280 DOI: 10.1007/BF03349775  1
1995 Letz B, Ackermann A, Canessa CM, Rossier BC, Korbmacher C. Amiloride-sensitive sodium channels in confluent M-1 mouse cortical collecting duct cells. The Journal of Membrane Biology. 148: 127-41. PMID 8606362 DOI: 10.1007/BF00207269  1
1995 Canessa CM, Horisberger JD, Schild L, Rossier BC. Expression cloning of the epithelial sodium channel. Kidney International. 48: 950-5. PMID 8569104  1
1995 Schild L, Canessa CM, Shimkets RA, Gautschi I, Lifton RP, Rossier BC. A mutation in the epithelial sodium channel causing Liddle disease increases channel activity in the Xenopus laevis oocyte expression system. Proceedings of the National Academy of Sciences of the United States of America. 92: 5699-703. PMID 7777572 DOI: 10.1073/pnas.92.12.5699  1
1995 Burch LH, Talbot CR, Knowles MR, Canessa CM, Rossier BC, Boucher RC. Relative expression of the human epithelial Na+ channel subunits in normal and cystic fibrosis airways. The American Journal of Physiology. 269: C511-8. PMID 7653534  1
1995 Puoti A, May A, Canessa CM, Horisberger JD, Schild L, Rossier BC. The highly selective low-conductance epithelial Na channel of Xenopus laevis A6 kidney cells. The American Journal of Physiology. 269: C188-97. PMID 7631745  1
1995 Antolovic R, Schoner W, Geering K, Canessa C, Rossier BC, Horisberger JD. Labeling of a cysteine in the cardiotonic glycoside binding site by the steroid derivative HDMA. Febs Letters. 368: 169-72. PMID 7615075 DOI: 10.1016/0014-5793(95)00637-O  1
1995 Tchepichev S, Ueda J, Canessa C, Rossier BC, O'Brodovich H. Lung epithelial Na channel subunits are differentially regulated during development and by steroids. The American Journal of Physiology. 269: C805-12. PMID 7573414  1
1995 Fuller CM, Awayda MS, Arrate MP, Bradford AL, Morris RG, Canessa CM, Rossier BC, Benos DJ. Cloning of a bovine renal epithelial Na+ channel subunit. The American Journal of Physiology. 269: C641-54. PMID 7573394  1
1995 Hansson JH, Nelson-Williams C, Suzuki H, Schild L, Shimkets R, Lu Y, Canessa C, Iwasaki T, Rossier B, Lifton RP. Hypertension caused by a truncated epithelial sodium channel gamma subunit: genetic heterogeneity of Liddle syndrome. Nature Genetics. 11: 76-82. PMID 7550319 DOI: 10.1038/ng0995-76  1
1995 Stutts MJ, Canessa CM, Olsen JC, Hamrick M, Cohn JA, Rossier BC, Boucher RC. CFTR as a cAMP-dependent regulator of sodium channels. Science (New York, N.Y.). 269: 847-50. PMID 7543698  1
1994 Canessa CM, Schild L, Buell G, Thorens B, Gautschi I, Horisberger JD, Rossier BC. Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits. Nature. 367: 463-7. PMID 8107805 DOI: 10.1038/367463a0  1
1994 Shimkets RA, Warnock DG, Bositis CM, Nelson-Williams C, Hansson JH, Schambelan M, Gill JR, Ulick S, Milora RV, Findling JW, Canessa CM, Rossier BC, Lifton RP. Liddle's syndrome: Heritable human hypertension caused by mutations in the β subunit of the epithelial sodium channel Cell. 79: 407-414. PMID 7954808 DOI: 10.1016/0092-8674(94)90250-X  1
1994 Rotin D, Bar-Sagi D, O'Brodovich H, Merilainen J, Lehto VP, Canessa CM, Rossier BC, Downey GP. An SH3 binding region in the epithelial Na+ channel (alpha rENaC) mediates its localization at the apical membrane. The Embo Journal. 13: 4440-50. PMID 7925286  1
1994 Meisler MH, Barrow LL, Canessa CM, Rossier BC. SCNN1, an epithelial cell sodium channel gene in the conserved linkage group on mouse chromosome 6 and human chromosome 12. Genomics. 24: 185-6. PMID 7896277 DOI: 10.1006/geno.1994.1599  1
1994 Canessa CM, Merillat AM, Rossier BC. Membrane topology of the epithelial sodium channel in intact cells. The American Journal of Physiology. 267: C1682-90. PMID 7810611  1
1994 Duc C, Farman N, Canessa CM, Bonvalet JP, Rossier BC. Cell-specific expression of epithelial sodium channel alpha, beta, and gamma subunits in aldosterone-responsive epithelia from the rat: localization by in situ hybridization and immunocytochemistry. The Journal of Cell Biology. 127: 1907-21. PMID 7806569 DOI: 10.1083/jcb.127.6.1907  1
1994 Rossier BC, Canessa CM, Schild L, Horisberger JD. Epithelial sodium channels. Current Opinion in Nephrology and Hypertension. 3: 487-96. PMID 7804746  1
1994 Horisberger JD, Puoti A, Canessa C, Rossier BC. The amiloride receptor. The Clinical Investigator. 72: 695-7. PMID 7531520 DOI: 10.1007/BF00212992  1
1994 Canessa C, Jaisser F, Horisberger JD, Rossier BC. Structure-function relationship of Na,K-ATPase: The digitalis receptor Current Topics in Membranes. 41: 71-85. DOI: 10.1016/S0070-2161(08)60454-2  1
1993 Canessa CM, Horisberger JD, Rossier BC. Mutation of a tyrosine in the H3-H4 ectodomain of Na,K-ATPase alpha subunit confers ouabain resistance. The Journal of Biological Chemistry. 268: 17722-6. PMID 8394348  1
1993 Canessa CM, Horisberger JD, Rossier BC. Epithelial sodium channel related to proteins involved in neurodegeneration. Nature. 361: 467-70. PMID 8381523 DOI: 10.1038/361467a0  1
1993 O'Brodovich H, Canessa C, Ueda J, Rafii B, Rossier BC, Edelson J. Expression of the epithelial Na+ channel in the developing rat lung. The American Journal of Physiology. 265: C491-6. PMID 7690185  1
1993 Horisberger JD, Canessa C, Rossier BC. The epithelial sodium channel: Recent developments Cellular Physiology and Biochemistry. 3: 283-294. DOI: 10.1159/000154694  1
1992 Canessa CM, Schafer JA. AVP stimulates Na+ transport in primary cultures of rabbit cortical collecting duct cells. The American Journal of Physiology. 262: F454-61. PMID 1558162  1
1992 Jaisser F, Canessa CM, Horisberger JD, Rossier BC. Primary sequence and functional expression of a novel ouabain-resistant Na,K-ATPase. The beta subunit modulates potassium activation of the Na,K-pump. The Journal of Biological Chemistry. 267: 16895-903. PMID 1380956  1
1992 Canessa CM, Horisberger JD, Louvard D, Rossier BC. Mutation of a cysteine in the first transmembrane segment of Na,K-ATPase alpha subunit confers ouabain resistance. The Embo Journal. 11: 1681-7. PMID 1316269  1
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