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Rudolph J. Castellani, MD - Publications

Affiliations: 
Pathology University of Maryland School of Medicine, Baltimore, MD, United States 
Area:
Neuropathology
Website:
http://www.umm.edu/doctors/rudolph__castellani.html

177 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Iverson GL, Keene CD, Perry G, Castellani RJ. The Need to Separate Chronic Traumatic Encephalopathy Neuropathology from Clinical Features. Journal of Alzheimer's Disease : Jad. PMID 29103039 DOI: 10.3233/JAD-170654  1
2017 Manley GT, Gardner AJ, Schneider KJ, Guskiewicz KM, Bailes J, Cantu RC, Castellani RJ, Turner M, Jordan BD, Randolph C, Dvořák J, Hayden KA, Tator CH, McCrory P, Iverson GL. A systematic review of potential long-term effects of sport-related concussion. British Journal of Sports Medicine. PMID 28455362 DOI: 10.1136/bjsports-2017-097791  0.52
2016 Kelley AR, Perry G, Bethea C, Castellani RJ, Bach SB. Molecular Mapping Alzheimer's Disease: MALDI Imaging of Formalin-fixed, Paraffin-embedded Human Hippocampal Tissue. The Open Neurology Journal. 10: 88-98. PMID 27843502 DOI: 10.2174/1874205X01610010088  1
2015 Kelley AR, Perry G, Castellani RJ, Bach SB. Laser-Induced In-Source Decay Applied to the Determination of Amyloid-Beta in Alzheimer's Brains. Acs Chemical Neuroscience. PMID 26720297 DOI: 10.1021/acschemneuro.5b00295  1
2015 Iverson GL, Gardner AJ, McCrory P, Zafonte R, Castellani RJ. A critical review of chronic traumatic encephalopathy. Neuroscience and Biobehavioral Reviews. 56: 276-293. PMID 26183075 DOI: 10.1016/j.neubiorev.2015.05.008  0.52
2015 Mehta RI, Tosun C, Ivanova S, Tsymbalyuk N, Famakin BM, Kwon MS, Castellani RJ, Gerzanich V, Simard JM. Sur1-Trpm4 Cation Channel Expression in Human Cerebral Infarcts. Journal of Neuropathology and Experimental Neurology. 74: 835-49. PMID 26172285 DOI: 10.1097/NEN.0000000000000223  1
2015 Castellani RJ, Perry G, Iverson GL. Chronic effects of mild neurotrauma: putting the cart before the horse? Journal of Neuropathology and Experimental Neurology. 74: 493-9. PMID 25933385 DOI: 10.1097/NEN.0000000000000193  1
2015 Pelcovits A, Marriotti R, Heath J, Perry G, Castellani RJ. Simultaneous onset of Alzheimer's disease in a husband and wife in their mid-fifties: what do we really know about environmental factors? The Open Neurology Journal. 9: 1-3. PMID 25932054 DOI: 10.2174/1874205X01509010001  1
2015 Castellani RJ. Chronic traumatic encephalopathy: A paradigm in search of evidence? Laboratory Investigation; a Journal of Technical Methods and Pathology. 95: 576-84. PMID 25867769 DOI: 10.1038/labinvest.2015.54  1
2015 Carvalho C, Correia SC, Perry G, Castellani RJ, Moreira PI. Cerebrovascular and mitochondrial abnormalities in Alzheimer's disease: a brief overview. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 25608860 DOI: 10.1007/s00702-015-1367-7  1
2015 Surampalli A, Gold BT, Smith C, Castellani RJ, Khare M, Yu H, Nguyen C, Lan M, Wencel M, Wigal S, Caiozzo V, Kimonis V. A case report comparing clinical, imaging and neuropsychological assessment findings in twins discordant for the VCP p.R155C mutation. Neuromuscular Disorders : Nmd. 25: 177-83. PMID 25582679 DOI: 10.1016/j.nmd.2014.10.003  1
2015 Mehta RI, Mehta RI, Choi JM, Mukherjee A, Castellani RJ. Hydrophilic polymer embolism and associated vasculopathy of the lung: prevalence in a retrospective autopsy study. Human Pathology. 46: 191-201. PMID 25543660 DOI: 10.1016/j.humpath.2014.09.011  1
2015 Solomon G, Collins MW, Pearce KL. Comments Neurosurgery. 76: 655-656. DOI: 10.1227/NEU.0000000000000722  1
2015 Shamirian S, Nalbandian A, Khare M, Castellani R, Kim R, Kimonis VE. Early-onset Alzheimers and cortical vision impairment in a woman with valosin-containing protein disease associated with 2 APOE e4/APOE e4 genotype Alzheimer Disease and Associated Disorders. 29: 90-93. DOI: 10.1097/WAD.0b013e318298e54f  1
2015 Iverson GL, Gardner AJ, McCrory P, Zafonte R, Castellani RJ. A critical review of chronic traumatic encephalopathy Neuroscience and Biobehavioral Reviews. 56: 276-293. DOI: 10.1016/j.neubiorev.2015.05.008  0.52
2015 Pelcovits A, Marriotti R, Heath J, Perry G, Castellani RJ. Simultaneous Onset of Alzheimer’s Disease in a Husband and Wife in their Mid-Fifties: What do we Really know about Environmental Factors? Open Neurology Journal. 9: 1-3.  1
2014 Fornicola W, Pelcovits A, Li BX, Heath J, Perry G, Castellani RJ. Alzheimer Disease Pathology in Middle Age Reveals a Spatial-Temporal Disconnect Between Amyloid-β and Phosphorylated Tau. The Open Neurology Journal. 8: 22-6. PMID 25628768 DOI: 10.2174/1874205X01408010022  1
2014 Choi J, Ravipati A, Nimmagadda V, Schubert M, Castellani RJ, Russell JW. Potential roles of PINK1 for increased PGC-1α-mediated mitochondrial fatty acid oxidation and their associations with Alzheimer disease and diabetes. Mitochondrion. 18: 41-8. PMID 25260493 DOI: 10.1016/j.mito.2014.09.005  1
2014 Palm R, Chang J, Blair J, Garcia-Mesa Y, Lee HG, Castellani RJ, Smith MA, Zhu X, Casadesus G. Down-regulation of serum gonadotropins but not estrogen replacement improves cognition in aged-ovariectomized 3xTg AD female mice. Journal of Neurochemistry. 130: 115-25. PMID 24601954 DOI: 10.1111/jnc.12706  1
2014 Blair JA, Siedlak SL, Wolfram JA, Nunomura A, Castellani RJ, Ferreira ST, Klein WL, Wang Y, Casadesus G, Smith MA, Perry G, Zhu X, Lee HG. Accumulation of intraneuronal amyloid-β is common in normal brain. Current Alzheimer Research. 11: 317-24. PMID 24597504 DOI: 10.2174/1567205011666140302200902  1
2014 Perry G, Castellani R. Plaques and tangles: Birthmarks of the aging soul Biochemical Pharmacology. 88: 423-425. PMID 24486570 DOI: 10.1016/j.bcp.2014.01.028  1
2014 Castellani RJ, Perry G. The complexities of the pathology-pathogenesis relationship in Alzheimer disease. Biochemical Pharmacology. 88: 671-6. PMID 24447936 DOI: 10.1016/j.bcp.2014.01.009  1
2014 Lin JM, Heath JE, Twaddell WS, Castellani RJ. Undifferentiated sarcoma of the liver: a case study of an erythropoietin-secreting tumor. International Journal of Surgical Pathology. 22: 555-8. PMID 24038117 DOI: 10.1177/1066896913503490  1
2014 Castellani RJ, Zhu X, Perry G, Moreira PI. Alzheimer's Disease: An Overview Reference Module in Biomedical Research. DOI: 10.1016/B978-0-12-801238-3.04491-3  1
2014 Castellani RJ, Moreira PI, Zhu X, Perry G. Alzheimer's Disease: Pathology and Pathogenesis Reference Module in Biomedical Research. DOI: 10.1016/B978-0-12-801238-3.00160-4  1
2014 Fornicola W, Pelcovits A, Li BX, Heath J, Perry G, Castellani RJ. Alzheimer Disease Pathology in Middle Age Reveals a Spatial-Temporal Disconnect Between Amyloid-β and Phosphorylated Tau Open Neurology Journal. 8: 22-26.  1
2013 Fujioka H, Phelix CF, Friedland RP, Zhu X, Perry EA, Castellani RJ, Perry G. Apolipoprotein E4 prevents growth of malaria at the intraerythrocyte stage: implications for differences in racial susceptibility to Alzheimer's disease. Journal of Health Care For the Poor and Underserved. 24: 70-8. PMID 24241262 DOI: 10.1353/hpu.2014.0009  1
2013 Williams WM, Torres S, Siedlak SL, Castellani RJ, Perry G, Smith MA, Zhu X. Antimicrobial peptide β-defensin-1 expression is upregulated in Alzheimer's brain. Journal of Neuroinflammation. 10: 127. PMID 24139179 DOI: 10.1186/1742-2094-10-127  1
2013 Tosun C, Kurland DB, Mehta R, Castellani RJ, deJong JL, Kwon MS, Woo SK, Gerzanich V, Simard JM. Inhibition of the Sur1-Trpm4 channel reduces neuroinflammation and cognitive impairment in subarachnoid hemorrhage. Stroke; a Journal of Cerebral Circulation. 44: 3522-8. PMID 24114458 DOI: 10.1161/STROKEAHA.113.002904  1
2013 Correia SC, Perry G, Castellani R, Moreira PI. Is exercise-in-a-bottle likely to proffer new insights into Alzheimer's disease? Journal of Neurochemistry. 127: 4-6. PMID 24074055 DOI: 10.1111/jnc.12406  1
2013 Mehta RI, Ivanova S, Tosun C, Castellani RJ, Gerzanich V, Simard JM. Sulfonylurea receptor 1 expression in human cerebral infarcts. Journal of Neuropathology and Experimental Neurology. 72: 871-83. PMID 23965746 DOI: 10.1097/NEN.0b013e3182a32e40  1
2013 Choi J, Batchu VV, Schubert M, Castellani RJ, Russell JW. A novel PGC-1α isoform in brain localizes to mitochondria and associates with PINK1 and VDAC. Biochemical and Biophysical Research Communications. 435: 671-7. PMID 23688429 DOI: 10.1016/j.bbrc.2013.05.041  1
2013 Perry EA, Castellani RJ, Moreira PI, Nunomura A, Lui Q, Harris PL, Sayre LM, Szweda PA, Szweda LI, Zhu X, Smith MA, Perry G. Neurofilaments are the major neuronal target of hydroxynonenal-mediated protein cross-links. Free Radical Research. 47: 507-10. PMID 23566300 DOI: 10.3109/10715762.2013.794265  1
2013 Tannous O, Stall AC, Griffith C, Donaldson CT, Castellani RJ, Pellegrini VD. Heterotopic bone formation about the hip undergoes endochondral ossification: a rabbit model. Clinical Orthopaedics and Related Research. 471: 1584-92. PMID 23361932 DOI: 10.1007/s11999-013-2801-5  1
2013 Santos RX, Correia SC, Zhu X, Smith MA, Moreira PI, Castellani RJ, Nunomura A, Perry G. Mitochondrial DNA oxidative damage and repair in aging and Alzheimer's disease. Antioxidants & Redox Signaling. 18: 2444-57. PMID 23216311 DOI: 10.1089/ars.2012.5039  1
2013 Balan IS, Saladino AJ, Aarabi B, Castellani RJ, Wade C, Stein DM, Eisenberg HM, Chen HH, Fiskum G. Cellular alterations in human traumatic brain injury: changes in mitochondrial morphology reflect regional levels of injury severity. Journal of Neurotrauma. 30: 367-81. PMID 23131111 DOI: 10.1089/neu.2012.2339  1
2013 Hersh DS, Mehta RI, Woodworth GF, Castellani RJ. The molecular pathology of primary brain tumors Pathology Case Reviews. 18: 210-220. DOI: 10.1097/PCR.0b013e3182a9ac4b  1
2013 Huebner TA, Kligerman S, Castellani RJ, Burke A. Nonspecific interstitial pneumonia associated with dermatomyositis with and without anti-jo-1 autoantibodies Pathology Case Reviews. 18: 127-131. DOI: 10.1097/PCR.0b013e31829205e4  1
2013 Choi J, Peterson E, Kligerman S, Drachenberg C, Castellani R, Burke A. Hermansky-Pudlak syndrome-associated interstitial pneumonia: Pathologic and imaging findings Pathology Case Reviews. 18: 111-114. DOI: 10.1097/PCR.0b013e3182920481  1
2013 Castellani RJ. Diagnostic challenges in surgical neuropathology Pathology Case Reviews. 18: 243. DOI: 10.1097/PCR.0000000000000012  1
2013 Castellani RJ. Challenging issues in brain tumor pathology Pathology Case Reviews. 18: 209. DOI: 10.1097/PCR.0000000000000007  1
2013 Bonda DJ, Castellani RJ, Lee HG, Tabaton M, Casadesus G, Perry G, Zhu X, Smith MA. Down syndrome and Alzheimer disease: A "multi-hit" hypothesis based on multiple contributing factors resulting in pleotrophic consequences Alzheimer's Disease Research Compendium. 183-193.  1
2012 Kunte H, Busch MA, Trostdorf K, Vollnberg B, Harms L, Mehta RI, Castellani RJ, Mandava P, Kent TA, Simard JM. Hemorrhagic transformation of ischemic stroke in diabetics on sulfonylureas. Annals of Neurology. 72: 799-806. PMID 23280795 DOI: 10.1002/ana.23680  1
2012 Castellani RJ, Perry G. Pathogenesis and disease-modifying therapy in Alzheimer's disease: the flat line of progress. Archives of Medical Research. 43: 694-8. PMID 23085451 DOI: 10.1016/j.arcmed.2012.09.009  1
2012 Sharma HS, Castellani RJ, Smith MA, Sharma A. The blood-brain barrier in Alzheimer's disease: novel therapeutic targets and nanodrug delivery. International Review of Neurobiology. 102: 47-90. PMID 22748826 DOI: 10.1016/B978-0-12-386986-9.00003-X  1
2012 Nunomura A, Moreira PI, Castellani RJ, Lee HG, Zhu X, Smith MA, Perry G. Oxidative damage to RNA in aging and neurodegenerative disorders. Neurotoxicity Research. 22: 231-48. PMID 22669748 DOI: 10.1007/s12640-012-9331-x  1
2012 Williams WM, Castellani RJ, Weinberg A, Perry G, Smith MA. Do β-defensins and other antimicrobial peptides play a role in neuroimmune function and neurodegeneration? Thescientificworldjournal. 2012: 905785. PMID 22606066 DOI: 10.1100/2012/905785  1
2012 Nelson PT, Alafuzoff I, Bigio EH, Bouras C, Braak H, Cairns NJ, Castellani RJ, Crain BJ, Davies P, Del Tredici K, Duyckaerts C, Frosch MP, Haroutunian V, Hof PR, Hulette CM, et al. Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature. Journal of Neuropathology and Experimental Neurology. 71: 362-81. PMID 22487856 DOI: 10.1097/NEN.0b013e31825018f7  1
2012 Castellani RJ, Moreira PI, Perry G, Zhu X. The role of iron as a mediator of oxidative stress in Alzheimer disease. Biofactors (Oxford, England). 38: 133-8. PMID 22447715 DOI: 10.1002/biof.1010  1
2012 Wang X, Snape M, Klann E, Stone JG, Singh A, Petersen RB, Castellani RJ, Casadesus G, Smith MA, Zhu X. Activation of the extracellular signal-regulated kinase pathway contributes to the behavioral deficit of fragile x-syndrome. Journal of Neurochemistry. 121: 672-9. PMID 22393900 DOI: 10.1111/j.1471-4159.2012.07722.x  1
2012 Perry G, Phelix CF, Nunomura A, Colom LV, Castellani RJ, Petersen RB, Lee HG, Zhu X. Untangling the vascular web from Alzheimer disease and oxidative stress. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 39: 4. PMID 22384486  1
2012 Zhu X, Castellani RJ, Ziats NP, Petersen RB, Gon Lee H, Perry G. Mark A. Smith: neurocytochemistry innovator. Journal of Neurochemistry. 120: 1139-40. PMID 22268813 DOI: 10.1111/j.1471-4159.2012.07656.x  1
2012 Zhu X, Castellani RJ, Moreira PI, Aliev G, Shenk JC, Siedlak SL, Harris PL, Fujioka H, Sayre LM, Szweda PA, Szweda LI, Smith MA, Perry G. Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover. Free Radical Biology & Medicine. 52: 699-704. PMID 22137893 DOI: 10.1016/j.freeradbiomed.2011.11.004  1
2011 Koltz MT, Tosun C, Kurland DB, Coksaygan T, Castellani RJ, Ivanova S, Gerzanich V, Simard JM. Tandem insults of prenatal ischemia plus postnatal raised intrathoracic pressure in a novel rat model of encephalopathy of prematurity. Journal of Neurosurgery. Pediatrics. 8: 628-39. PMID 22132923 DOI: 10.3171/2011.9.PEDS11174  1
2011 Ziats NP, Petersen RB, Lee HG, Castellani RJ, Perry G, Zhu X. Mark A. Smith, 1965-2010: consummate student of pathogenesis. International Journal of Clinical and Experimental Pathology. 4: 731-2. PMID 22076176  1
2011 Castellani RJ, Gupta Y, Sheng B, Siedlak SL, Harris PL, Coller JM, Perry G, Lee HG, Tabaton M, Smith MA, Wang X, Zhu X. A novel origin for granulovacuolar degeneration in aging and Alzheimer's disease: parallels to stress granules. Laboratory Investigation; a Journal of Technical Methods and Pathology. 91: 1777-86. PMID 21968813 DOI: 10.1038/labinvest.2011.149  1
2011 Castellani RJ, Petersen RB, Lee HG, Zhu X, Perry G. Mark A. Smith: the scientist, the man. International Journal of Experimental Pathology. 92: 297-8. PMID 21917030 DOI: 10.1111/j.1365-2613.2011.00785.x  1
2011 Stone JG, Casadesus G, Gustaw-Rothenberg K, Siedlak SL, Wang X, Zhu X, Perry G, Castellani RJ, Smith MA. Frontiers in Alzheimer's disease therapeutics. Therapeutic Advances in Chronic Disease. 2: 9-23. PMID 21743833 DOI: 10.1177/2040622310382817  1
2011 Stone JG, Siedlak SL, Tabaton M, Hirano A, Castellani RJ, Santocanale C, Perry G, Smith MA, Zhu X, Lee HG. The cell cycle regulator phosphorylated retinoblastoma protein is associated with tau pathology in several tauopathies. Journal of Neuropathology and Experimental Neurology. 70: 578-87. PMID 21666500 DOI: 10.1097/NEN.0b013e3182204414  1
2011 Wang X, Su B, Liu W, He X, Gao Y, Castellani RJ, Perry G, Smith MA, Zhu X. DLP1-dependent mitochondrial fragmentation mediates 1-methyl-4-phenylpyridinium toxicity in neurons: implications for Parkinson's disease. Aging Cell. 10: 807-23. PMID 21615675 DOI: 10.1111/j.1474-9726.2011.00721.x  1
2011 Bonda DJ, Castellani RJ, Zhu X, Nunomura A, Lee HG, Perry G, Smith MA. A novel perspective on tau in Alzheimer's disease. Current Alzheimer Research. 8: 639-42. PMID 21605042 DOI: 10.2174/156720511796717131  1
2011 Xu DS, Dirks MS, Quezado MM, Lubensky IA, Zhuang Z, Lonser RR, Asthagiri AR. A von Hippel-Lindau disease-associated microcystic adenoma of the ethmoid sinus: case report. Neurosurgery. 69: E1017-21; discussion. PMID 21572360 DOI: 10.1227/NEU.0b013e318223b7a7  1
2011 Castellani RJ, Smith MA. Compounding artefacts with uncertainty, and an amyloid cascade hypothesis that is 'too big to fail'. The Journal of Pathology. 224: 147-52. PMID 21557219 DOI: 10.1002/path.2885  1
2011 Castellani RJ. Obituary: Mark A Smith. Expert Review of Neurotherapeutics. 11: 463-4. PMID 21375451 DOI: 10.1586/ern.11.17  1
2011 Hoffman WH, Siedlak SL, Wang Y, Castellani RJ, Smith MA. Oxidative damage is present in the fatal brain edema of diabetic ketoacidosis. Brain Research. 1369: 194-202. PMID 21040714 DOI: 10.1016/j.brainres.2010.10.085  1
2011 Castellani RJ, Nugent SL, Morrison AL, Zhu X, Lee HG, Harris PL, Bajić V, Sharma HS, Chen SG, Oettgen P, Perry G, Smith MA. CD3 in Lewy pathology: does the abnormal recall of neurodevelopmental processes underlie Parkinson's disease. Journal of Neural Transmission (Vienna, Austria : 1996). 118: 23-6. PMID 20972807 DOI: 10.1007/s00702-010-0485-5  1
2011 Castellani RJ, Lee HG, Petersen RB, Zhu X, Perry G. Pathological phenotype in familial neurodegenerative disease: Implications for families and therapeutic constructs Therapy. 8: 475-479. DOI: 10.2217/thy.11.62  1
2011 Castellani RJ, Zhu X, Perry G. Alzheimer's disease therapy: A moving target Therapy. 8: 457-458. DOI: 10.2217/thy.11.56  1
2010 Clark TA, Lee HP, Rolston RK, Zhu X, Marlatt MW, Castellani RJ, Nunomura A, Casadesus G, Smith MA, Lee HG, Perry G. Oxidative Stress and its Implications for Future Treatments and Management of Alzheimer Disease. International Journal of Biomedical Science : Ijbs. 6: 225-227. PMID 21765811  1
2010 Castellani RJ, Rolston RK, Smith MA. Alzheimer disease. Disease-a-Month : Dm. 56: 484-546. PMID 20831921 DOI: 10.1016/j.disamonth.2010.06.001  1
2010 Shah RS, Shin RK, Castellani RJ. Granulocytic sarcoma mimicking HSV encephalitis. The Neurologist. 16: 319-21. PMID 20827123 DOI: 10.1097/NRL.0b013e3181b0be8d  1
2010 Zou WQ, Puoti G, Xiao X, Yuan J, Qing L, Cali I, Shimoji M, Langeveld JP, Castellani R, Notari S, Crain B, Schmidt RE, Geschwind M, Dearmond SJ, Cairns NJ, et al. Variably protease-sensitive prionopathy: a new sporadic disease of the prion protein. Annals of Neurology. 68: 162-72. PMID 20695009 DOI: 10.1002/ana.22094  1
2010 Bonda DJ, Mailankot M, Stone JG, Garrett MR, Staniszewska M, Castellani RJ, Siedlak SL, Zhu X, Lee HG, Perry G, Nagaraj RH, Smith MA. Indoleamine 2,3-dioxygenase and 3-hydroxykynurenine modifications are found in the neuropathology of Alzheimer's disease. Redox Report : Communications in Free Radical Research. 15: 161-8. PMID 20663292 DOI: 10.1179/174329210X12650506623645  1
2010 Fyfe JC, Al-Tamimi RA, Castellani RJ, Rosenstein D, Goldowitz D, Henthorn PS. Inherited neuroaxonal dystrophy in dogs causing lethal, fetal-onset motor system dysfunction and cerebellar hypoplasia. The Journal of Comparative Neurology. 518: 3771-84. PMID 20653033 DOI: 10.1002/cne.22423  1
2010 Lee HP, Zhu X, Casadesus G, Castellani RJ, Nunomura A, Smith MA, Lee HG, Perry G. Antioxidant approaches for the treatment of Alzheimer's disease. Expert Review of Neurotherapeutics. 10: 1201-8. PMID 20586698 DOI: 10.1586/ern.10.74  1
2010 Moh CF, Siedlak SL, Tabaton M, Perry G, Castellani RJ, Smith MA. Paraffin-embedded tissue (PET) blot method: application to Alzheimer disease. Journal of Neuroscience Methods. 190: 244-7. PMID 20580647 DOI: 10.1016/j.jneumeth.2010.05.010  1
2010 Shvartsbeyn M, Phillips DG, Markey MA, Morrison A, DeJong JL, Castellani RJ. Cocaine-induced intracerebral hemorrhage in a patient with cerebral amyloid angiopathy. Journal of Forensic Sciences. 55: 1389-92. PMID 20456585 DOI: 10.1111/j.1556-4029.2010.01410.x  1
2010 Mondragón-Rodríguez S, Basurto-Islas G, Lee HG, Perry G, Zhu X, Castellani RJ, Smith MA. Causes versus effects: the increasing complexities of Alzheimer's disease pathogenesis. Expert Review of Neurotherapeutics. 10: 683-91. PMID 20420489 DOI: 10.1586/ern.10.27  1
2010 Heath JE, Siedlak SL, Zhu X, Lee HG, Thakur A, Yan R, Perry G, Smith MA, Castellani RJ. Widespread distribution of reticulon-3 in various neurodegenerative diseases. Neuropathology : Official Journal of the Japanese Society of Neuropathology. 30: 574-9. PMID 20374499 DOI: 10.1111/j.1440-1789.2010.01107.x  1
2010 Rodrigues R, Bonda DJ, Perry G, Castellani RJ, Casadesus G, Lee HG, Lee HP, Wang X, Zhu X, Petersen RB, Smith MA. Oxidative stress and neurodegeneration: An inevitable consequence of aging? Implications for therapy Brain Protection in Schizophrenia, Mood and Cognitive Disorders. 305-323. DOI: 10.1007/978-90-481-8553-5_10  1
2009 Rolston RK, Perry G, Zhu X, Castellani RJ, Dwyer BE, Lee HG, Petersen RB, Smith MA. Iron: A Pathological Mediator of Alzheimer Disease? Agro Food Industry Hi-Tech. 19: 33-36. PMID 21544251  1
2009 Friedlich AL, Rolston RK, Zhu X, Marlatt MW, Castellani RJ, Nunomura A, Lee HG, Casadesus G, Perry G, Smith MA. Treatment advances in Alzheimer's disease based on the oxidative stress model. F1000 Medicine Reports. 1. PMID 20948726 DOI: 10.3410/M1-54  1
2009 Bonda DJ, Evans TA, Santocanale C, Llosá JC, Viña J, Bajic V, Castellani RJ, Siedlak SL, Perry G, Smith MA, Lee HG. Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease. Aging. 1: 382-8. PMID 19946466  1
2009 Lee HG, Chen Q, Wolfram JA, Richardson SL, Liner A, Siedlak SL, Zhu X, Ziats NP, Fujioka H, Felsher DW, Castellani RJ, Valencik ML, McDonald JA, Hoit BD, Lesnefsky EJ, et al. Cell cycle re-entry and mitochondrial defects in myc-mediated hypertrophic cardiomyopathy and heart failure. Plos One. 4: e7172. PMID 19779629 DOI: 10.1371/journal.pone.0007172  1
2009 Cali I, Castellani R, Alshekhlee A, Cohen Y, Blevins J, Yuan J, Langeveld JP, Parchi P, Safar JG, Zou WQ, Gambetti P. Co-existence of scrapie prion protein types 1 and 2 in sporadic Creutzfeldt-Jakob disease: its effect on the phenotype and prion-type characteristics. Brain : a Journal of Neurology. 132: 2643-58. PMID 19734292 DOI: 10.1093/brain/awp196  1
2009 Su B, Liu H, Wang X, Chen SG, Siedlak SL, Kondo E, Choi R, Takeda A, Castellani RJ, Perry G, Smith MA, Zhu X, Lee HG. Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease. Molecular Neurodegeneration. 4: 32. PMID 19627592 DOI: 10.1186/1750-1326-4-32  1
2009 Castellani RJ, Lee HG, Siedlak SL, Nunomura A, Hayashi T, Nakamura M, Zhu X, Perry G, Smith MA. Reexamining Alzheimer's disease: evidence for a protective role for amyloid-beta protein precursor and amyloid-beta. Journal of Alzheimer's Disease : Jad. 18: 447-52. PMID 19584435 DOI: 10.3233/JAD-2009-1151  1
2009 Castellani RJ, Zhu X, Lee HG, Smith MA, Perry G. Molecular pathogenesis of Alzheimer's disease: reductionist versus expansionist approaches. International Journal of Molecular Sciences. 10: 1386-406. PMID 19399255 DOI: 10.3390/ijms10031386  1
2009 Nunomura A, Hofer T, Moreira PI, Castellani RJ, Smith MA, Perry G. RNA oxidation in Alzheimer disease and related neurodegenerative disorders. Acta Neuropathologica. 118: 151-66. PMID 19271225 DOI: 10.1007/s00401-009-0508-1  1
2009 Gonzalez-Cuyar LF, Tavora F, Shaw K, Castellani RJ, Dejong JL. Sudden unexpected death in lymphocytic hypophysitis. The American Journal of Forensic Medicine and Pathology. 30: 61-3. PMID 19237858 DOI: 10.1097/PAF.0b013e3181873851  1
2009 Lee HG, Casadesus G, Nunomura A, Zhu X, Castellani RJ, Richardson SL, Perry G, Felsher DW, Petersen RB, Smith MA. The neuronal expression of MYC causes a neurodegenerative phenotype in a novel transgenic mouse. The American Journal of Pathology. 174: 891-7. PMID 19164506 DOI: 10.2353/ajpath.2009.080583  1
2009 Lee HG, Casadesus G, Zhu X, Castellani RJ, McShea A, Perry G, Petersen RB, Bajic V, Smith MA. Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease. Neurochemistry International. 54: 84-8. PMID 19114068 DOI: 10.1016/j.neuint.2008.10.013  1
2009 Stone JG, Rolston RK, Ueda M, Lee HG, Richardson SL, Castellani RJ, Perry G, Smith MA. Evidence for the novel expression of human kallikrein-related peptidase 3, prostate-specific antigen, in the brain. International Journal of Clinical and Experimental Pathology. 2: 267-74. PMID 19079621  1
2009 Castellani RJ, Perry G, Smith MA. Is Alzheimer's disease a myth? When is disease a disease? Current Alzheimer Research. 6: 82. DOI: 10.2174/156720509787313925  1
2009 Gonzalez-Cuyar LF, Tavora F, Caminha I, Perry G, Smith MA, Castellani RJ. Cellular respiration and tumor suppressor genes Cellular Respiration and Carcinogenesis. 131-144. DOI: 10.1007/978-1-59745-435-3_10  1
2009 Nunomura A, Takeda A, Moreira PI, Castellani RJ, Lee HG, Zhu X, Smith MA, Perry G. Neurofibrillary tangle formation as a protective response to oxidative stress in Alzheimer's disease Current Hypotheses and Research Milestones in Alzheimer's Disease. 103-113. DOI: 10.1007/978-0-387-87995-6_9  1
2009 Marlatt MW, Moreira PI, Lee Hg, Casadesus G, Castellani RJ, Takeda A, Nunomura A, Zhu X, Perry G, Smith MA. Therapeutic opportunities in Alzheimer disease: Current concepts Frontiers in Medicinal Chemistry. 4: 767-788.  1
2008 Myung NH, Zhu X, Kruman II, Castellani RJ, Petersen RB, Siedlak SL, Perry G, Smith MA, Lee HG. Evidence of DNA damage in Alzheimer disease: phosphorylation of histone H2AX in astrocytes. Age (Dordrecht, Netherlands). 30: 209-15. PMID 19424844 DOI: 10.1007/s11357-008-9050-7  1
2008 Castellani RJ, Nunomura A, Rolston RK, Moreira PI, Takeda A, Perry G, Smith MA. Sublethal RNA oxidation as a mechanism for neurodegenerative disease. International Journal of Molecular Sciences. 9: 789-806. PMID 19325784 DOI: 10.3390/ijms9050789  1
2008 Bryan KJ, Zhu X, Harris PL, Perry G, Castellani RJ, Smith MA, Casadesus G. Expression of CD74 is increased in neurofibrillary tangles in Alzheimer's disease. Molecular Neurodegeneration. 3: 13. PMID 18786268 DOI: 10.1186/1750-1326-3-13  1
2008 Perry G, Castellani RJ, Moreira PI, Lee HG, Zhu X, Smith MA. Pathology's new role: defining disease process and protective responses. International Journal of Clinical and Experimental Pathology. 1: 1-4. PMID 18784818  1
2008 Castellani RJ, Nunomura A, Lee HG, Perry G, Smith MA. Phosphorylated tau: toxic, protective, or none of the above. Journal of Alzheimer's Disease : Jad. 14: 377-83. PMID 18688087  1
2008 Simard JM, Castellani RJ, Ivanova S, Koltz MT, Gerzanich V. Sulfonylurea receptor 1 in the germinal matrix of premature infants. Pediatric Research. 64: 648-52. PMID 18679166 DOI: 10.1203/PDR.0b013e318186e5a9  1
2008 Gambetti P, Dong Z, Yuan J, Xiao X, Zheng M, Alshekhlee A, Castellani R, Cohen M, Barria MA, Gonzalez-Romero D, Belay ED, Schonberger LB, Marder K, Harris C, Burke JR, et al. A novel human disease with abnormal prion protein sensitive to protease. Annals of Neurology. 63: 697-708. PMID 18571782 DOI: 10.1002/ana.21420  1
2008 Castellani RJ, Lee HG, Zhu X, Perry G, Smith MA. Alzheimer disease pathology as a host response. Journal of Neuropathology and Experimental Neurology. 67: 523-31. PMID 18520771 DOI: 10.1097/NEN.0b013e318177eaf4  1
2008 Gustaw KA, Garrett MR, Lee HG, Castellani RJ, Zagorski MG, Prakasam A, Siedlak SL, Zhu X, Perry G, Petersen RB, Friedland RP, Smith MA. Antigen-antibody dissociation in Alzheimer disease: a novel approach to diagnosis. Journal of Neurochemistry. 106: 1350-6. PMID 18485104 DOI: 10.1111/j.1471-4159.2008.05477.x  1
2008 Shah RS, Lee HG, Xiongwei Z, Perry G, Smith MA, Castellani RJ. Current approaches in the treatment of Alzheimer's disease. Biomedicine & Pharmacotherapy = BioméDecine & PharmacothéRapie. 62: 199-207. PMID 18407457 DOI: 10.1016/j.biopha.2008.02.005  1
2008 Gonzalez-Cuyar LF, Lam-Himlin D, Tavora F, Burke A, Castellani RJ. Bilateral internal carotid absence: a case report of a rare congenital anomaly. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 17: 113-6. PMID 18329557 DOI: 10.1016/j.carpath.2007.04.009  1
2008 Gonzalez-Cuyar LF, Perry G, Miyajima H, Atwood CS, Riveros-Angel M, Lyons PF, Siedlak SL, Smith MA, Castellani RJ. Redox active iron accumulation in aceruloplasminemia. Neuropathology : Official Journal of the Japanese Society of Neuropathology. 28: 466-71. PMID 18282164 DOI: 10.1111/j.1440-1789.2008.00901.x  1
2008 Zhu X, Siedlak SL, Wang Y, Perry G, Castellani RJ, Cohen ML, Smith MA. Neuronal binucleation in Alzheimer disease hippocampus. Neuropathology and Applied Neurobiology. 34: 457-65. PMID 17995921 DOI: 10.1111/j.1365-2990.2007.00908.x  1
2008 Gonzalez-Cuyar LF, Morrison AL, Perry G, DeJong JJ, Smith MA, Castellani RJ. Cerebrotendinous xanthomatosis: A critical update Future Neurology. 3: 491-501. DOI: 10.2217/14796708.3.4.491  1
2008 Bryan K, Lee HG, Perry G, Castellani RJ, Smith MA, Casadesus G. Nonestrogen-based hormonal therapies for Alzheimer's disease Future Neurology. 3: 399-407. DOI: 10.2217/14796708.3.4.399  1
2008 Rolston RK, Perry G, Zhu X, Castellani RJ, Dwyer BE, Lee HG, Petersen RB, Smith MA. Iron A pathological mediator of Alzheimer disease? Agro Food Industry Hi-Tech. 19: 33-36.  1
2008 Evans TA, Siedlak SL, Lu L, Fu X, Wang Z, McGinnis WR, Fakhoury E, Castellani RJ, Hazen SL, Walsh WJ, Lewis AT, Salomon RG, Smith MA, Perry G, Zhu X. The autistic phenotype exhibits a remarkably localized modification of brain protein by products of free radical-induced lipid oxidation American Journal of Biochemistry and Biotechnology. 4: 61-72.  1
2007 Castellani RJ. Vascular dementia and Alzheimer's disease: a waning dichotomy. Journal of Alzheimer's Disease : Jad. 12: 343-4. PMID 18290307  1
2007 Nunomura A, Moreira PI, Lee HG, Zhu X, Castellani RJ, Smith MA, Perry G. Neuronal death and survival under oxidative stress in Alzheimer and Parkinson diseases. Cns & Neurological Disorders Drug Targets. 6: 411-23. PMID 18220780 DOI: 10.2174/187152707783399201  1
2007 Castellani RJ, Perry G, Smith MA. The role of novel chitin-like polysaccharides in Alzheimer disease. Neurotoxicity Research. 12: 269-74. PMID 18201954 DOI: 10.1007/BF03033910  1
2007 Gonzalez-Cuyar LF, Hunter B, Harris PL, Perry G, Smith MA, Castellani RJ. Cerebrotendinous xanthomatosis: case report with evidence of oxidative stress. Redox Report : Communications in Free Radical Research. 12: 119-24. PMID 17623518 DOI: 10.1179/135100007X200173  1
2007 Castellani RJ, Moreira PI, Liu G, Dobson J, Perry G, Smith MA, Zhu X. Iron: the Redox-active center of oxidative stress in Alzheimer disease. Neurochemical Research. 32: 1640-5. PMID 17508283 DOI: 10.1007/s11064-007-9360-7  1
2007 Castellani RJ, Zhu X, Lee HG, Moreira PI, Perry G, Smith MA. Neuropathology and treatment of Alzheimer disease: did we lose the forest for the trees? Expert Review of Neurotherapeutics. 7: 473-85. PMID 17492899 DOI: 10.1586/14737175.7.5.473  1
2007 Lee HG, Zhu X, Castellani RJ, Nunomura A, Perry G, Smith MA. Amyloid-beta in Alzheimer disease: the null versus the alternate hypotheses. The Journal of Pharmacology and Experimental Therapeutics. 321: 823-9. PMID 17229880 DOI: 10.1124/jpet.106.114009  1
2007 Previll LA, Crosby ME, Castellani RJ, Bowser R, Perry G, Smith MA, Zhu X. Increased expression of p130 in Alzheimer disease. Neurochemical Research. 32: 639-44. PMID 17006760 DOI: 10.1007/s11064-006-9146-3  1
2007 Castellani RJ, Lee HG, Zhu X, Nunomura A, Perry G, Smith MA. Alzheimer's disease: Pathology vs etiology International Journal of Neuroprotection and Neuroregeneration. 4: 36-40.  1
2006 Smith MA, Zhu X, Lee HG, Harris PL, Fortino AE, Perry G, Castellani RJ. Sequestration of p27 within the cytoplasm of cardiac myocytes in chronic ischemic heart disease: pathogenic implications for ischemic cardiomyopathy. Age (Dordrecht, Netherlands). 28: 85-91. PMID 23598681 DOI: 10.1007/s11357-006-9001-0  1
2006 Lam-Himlin D, Espey MG, Perry G, Smith MA, Castellani RJ. Malignant glioma progression and nitric oxide. Neurochemistry International. 49: 764-8. PMID 16971023 DOI: 10.1016/j.neuint.2006.07.001  1
2006 Nunomura A, Castellani RJ, Zhu X, Moreira PI, Perry G, Smith MA. Involvement of oxidative stress in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 65: 631-41. PMID 16825950 DOI: 10.1097/01.jnen.0000228136.58062.bf  1
2006 Castellani RJ, Lee HG, Zhu X, Nunomura A, Perry G, Smith MA. Neuropathology of Alzheimer disease: pathognomonic but not pathogenic. Acta Neuropathologica. 111: 503-9. PMID 16718346 DOI: 10.1007/s00401-006-0071-y  1
2006 Nunomura A, Castellani RJ, Lee HG, Moreira PI, Zhu X, Perry G, Smith MA. Neuropathology in Alzheimer's disease: awaking from a hundred-year-old dream. Science of Aging Knowledge Environment : Sage Ke. 2006: pe10. PMID 16672726 DOI: 10.1126/sageke.2006.8.pe10  1
2006 Castellani RJ, Lee HG, Perry G, Smith MA. Antioxidant protection and neurodegenerative disease: the role of amyloid-beta and tau. American Journal of Alzheimer's Disease and Other Dementias. 21: 126-30. PMID 16634469 DOI: 10.1177/153331750602100213  1
2006 Castellani RJ, Zhu X, Lee HG, Perry G, Smith MA, Casadesus G. Neurogenesis in human hippocampus: Implications for Alzheimer disease pathogenesis Neuroembryology and Aging. 4: 175-182. DOI: 10.1159/000118927  1
2005 Castellani RJ, Siedlak SL, Fortino AE, Perry G, Ghetti B, Smith MA. Chitin-like polysaccharides in Alzheimer's disease brains. Current Alzheimer Research. 2: 419-23. PMID 16248847 DOI: 10.2174/156720505774330555  1
2005 Petersen RB, Siedlak SL, Lee HG, Kim YS, Nunomura A, Tagliavini F, Ghetti B, Cras P, Moreira PI, Castellani RJ, Guentchev M, Budka H, Ironside JW, Gambetti P, Smith MA, et al. Redox metals and oxidative abnormalities in human prion diseases. Acta Neuropathologica. 110: 232-8. PMID 16096758 DOI: 10.1007/s00401-005-1034-4  1
2005 Moreira PI, Smith MA, Zhu X, Nunomura A, Castellani RJ, Perry G. Oxidative stress and neurodegeneration. Annals of the New York Academy of Sciences. 1043: 545-52. PMID 16037277 DOI: 10.1196/annals.1333.062  1
2005 Lee HG, Castellani RJ, Zhu X, Perry G, Smith MA. Amyloid-beta in Alzheimer's disease: the horse or the cart? Pathogenic or protective? International Journal of Experimental Pathology. 86: 133-8. PMID 15910547 DOI: 10.1111/j.0959-9673.2005.00429.x  1
2005 He Q, Lowrie C, Shelton GD, Castellani RJ, Menotti-Raymond M, Murphy W, O'Brien SJ, Swanson WF, Fyfe JC. Inherited motor neuron disease in domestic cats: a model of spinal muscular atrophy. Pediatric Research. 57: 324-30. PMID 15635053 DOI: 10.1203/01.PDR.0000153625.46892.6F  1
2004 Aliev G, Castellani RJ, Petersen RB, Burnstock G, Perry G, Smith MA. Pathobiology of familial hypercholesterolemic atherosclerosis. Journal of Submicroscopic Cytology and Pathology. 36: 225-40. PMID 15906597  1
2004 Castellani RJ, Colucci M, Xie Z, Zou W, Li C, Parchi P, Capellari S, Pastore M, Rahbar MH, Chen SG, Gambetti P. Sensitivity of 14-3-3 protein test varies in subtypes of sporadic Creutzfeldt-Jakob disease. Neurology. 63: 436-42. PMID 15304573  1
2004 Castellani RJ, Honda K, Zhu X, Cash AD, Nunomura A, Perry G, Smith MA. Contribution of redox-active iron and copper to oxidative damage in Alzheimer disease. Ageing Research Reviews. 3: 319-26. PMID 15231239 DOI: 10.1016/j.arr.2004.01.002  1
2004 Castellani RJ, Perry G, Smith MA. Prion disease and Alzheimer's disease: pathogenic overlap. Acta Neurobiologiae Experimentalis. 64: 11-7. PMID 15190676  1
2004 Castellani RJ, Smith MA, Perry G, Friedland RP. Cerebral amyloid angiopathy: major contributor or decorative response to Alzheimer's disease pathogenesis. Neurobiology of Aging. 25: 599-602; discussion . PMID 15172735 DOI: 10.1016/j.neurobiolaging.2003.12.019  1
2004 Zhu X, McShea A, Harris PL, Raina AK, Castellani RJ, Funk JO, Shah S, Atwood C, Bowen R, Bowser R, Morelli L, Perry G, Smith MA. Elevated expression of a regulator of the G2/M phase of the cell cycle, neuronal CIP-1-associated regulator of cyclin B, in Alzheimer's disease. Journal of Neuroscience Research. 75: 698-703. PMID 14991845 DOI: 10.1002/jnr.20028  1
2004 Ghanbari HA, Ghanbari K, Harris PL, Jones PK, Kubat Z, Castellani RJ, Wolozin BL, Smith MA, Perry G. Oxidative damage in cultured human olfactory neurons from Alzheimer's disease patients. Aging Cell. 3: 41-4. PMID 14965355 DOI: 10.1111/j.1474-9728.2004.00083.x  1
2004 Lee HG, Ogawa O, Zhu X, O'Neill MJ, Petersen RB, Castellani RJ, Ghanbari H, Perry G, Smith MA. Aberrant expression of metabotropic glutamate receptor 2 in the vulnerable neurons of Alzheimer's disease. Acta Neuropathologica. 107: 365-71. PMID 14872255 DOI: 10.1007/s00401-004-0820-8  1
2003 Perry G, Castellani RJ, Smith MA, Harris PL, Kubat Z, Ghanbari K, Jones PK, Cordone G, Tabaton M, Wolozin B, Ghanbari H. Oxidative damage in the olfactory system in Alzheimer's disease. Acta Neuropathologica. 106: 552-6. PMID 12955399 DOI: 10.1007/s00401-003-0761-7  1
2003 Ogawa O, Lee HG, Zhu X, Raina A, Harris PL, Castellani RJ, Perry G, Smith MA. Increased p27, an essential component of cell cycle control, in Alzheimer's disease. Aging Cell. 2: 105-10. PMID 12882323  1
2003 Krefft TA, Graff-Radford NR, Dickson DW, Baker M, Castellani RJ. Familial primary progressive aphasia. Alzheimer Disease and Associated Disorders. 17: 106-12. PMID 12794388 DOI: 10.1097/00002093-200304000-00009  1
2003 Cash AD, Aliev G, Siedlak SL, Nunomura A, Fujioka H, Zhu X, Raina AK, Vinters HV, Tabaton M, Johnson AB, Paula-Barbosa M, Avíla J, Jones PK, Castellani RJ, Smith MA, et al. Microtubule reduction in Alzheimer's disease and aging is independent of tau filament formation. The American Journal of Pathology. 162: 1623-7. PMID 12707046  1
2003 Ogawa O, Zhu X, Lee HG, Raina A, Obrenovich ME, Bowser R, Ghanbari HA, Castellani RJ, Perry G, Smith MA. Ectopic localization of phosphorylated histone H3 in Alzheimer's disease: a mitotic catastrophe? Acta Neuropathologica. 105: 524-8. PMID 12677454 DOI: 10.1007/s00401-003-0684-3  1
2003 Perry G, Taddeo MA, Petersen RB, Castellani RJ, Harris PL, Siedlak SL, Cash AD, Liu Q, Nunomura A, Atwood CS, Smith MA. Adventiously-bound redox active iron and copper are at the center of oxidative damage in Alzheimer disease. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 16: 77-81. PMID 12572666 DOI: 10.1023/A:1020731021276  1
2002 Perry G, Taddeo MA, Nunomura A, Zhu X, Zenteno-Savin T, Drew KL, Shimohama S, Avila J, Castellani RJ, Smith MA. Comparative biology and pathology of oxidative stress in Alzheimer and other neurodegenerative diseases: beyond damage and response. Comparative Biochemistry and Physiology. Toxicology & Pharmacology : Cbp. 133: 507-13. PMID 12458179 DOI: 10.1016/S1532-0456(02)00119-9  1
2002 Perry G, Nunomura A, Hirai K, Zhu X, Pérez M, Avila J, Castellani RJ, Atwood CS, Aliev G, Sayre LM, Takeda A, Smith MA. Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases? Free Radical Biology & Medicine. 33: 1475-9. PMID 12446204 DOI: 10.1016/S0891-5849(02)01113-9  1
2002 Nunomura A, Chiba S, Kosaka K, Takeda A, Castellani RJ, Smith MA, Perry G. Neuronal RNA oxidation is a prominent feature of dementia with Lewy bodies. Neuroreport. 13: 2035-9. PMID 12438921 DOI: 10.1097/00001756-200211150-00009  1
2002 Hartzler AW, Zhu X, Siedlak SL, Castellani RJ, Avilá J, Perry G, Smith MA. The p38 pathway is activated in Pick disease and progressive supranuclear palsy: a mechanistic link between mitogenic pathways, oxidative stress, and tau. Neurobiology of Aging. 23: 855-9. PMID 12392790 DOI: 10.1016/S0197-4580(02)00029-5  1
2002 Bowen RL, Smith MA, Harris PL, Kubat Z, Martins RN, Castellani RJ, Perry G, Atwood CS. Elevated luteinizing hormone expression colocalizes with neurons vulnerable to Alzheimer's disease pathology. Journal of Neuroscience Research. 70: 514-8. PMID 12391612 DOI: 10.1002/jnr.10452  1
2002 Zhou F, Braddock JF, Hu Y, Zhu X, Castellani RJ, Smith MA, Drew KL. Microbial origin of glutamate, hibernation and tissue trauma: an in vivo microdialysis study. Journal of Neuroscience Methods. 119: 121-8. PMID 12323415 DOI: 10.1016/S0165-0270(02)00177-2  1
2002 Perry G, Sayre LM, Atwood CS, Castellani RJ, Cash AD, Rottkamp CA, Smith MA. The role of iron and copper in the aetiology of neurodegenerative disorders: therapeutic implications. Cns Drugs. 16: 339-52. PMID 11994023  1
2002 Guentchev M, Siedlak SL, Jarius C, Tagliavini F, Castellani RJ, Perry G, Smith MA, Budka H. Oxidative damage to nucleic acids in human prion disease. Neurobiology of Disease. 9: 275-81. PMID 11950273 DOI: 10.1006/nbdi.2002.0477  1
2002 Kikuchi A, Takeda A, Onodera H, Kimpara T, Hisanaga K, Sato N, Nunomura A, Castellani RJ, Perry G, Smith MA, Itoyama Y. Systemic increase of oxidative nucleic acid damage in Parkinson's disease and multiple system atrophy. Neurobiology of Disease. 9: 244-8. PMID 11895375 DOI: 10.1006/nbdi.2002.0466  1
2002 Castellani RJ, Perry G, Siedlak SL, Nunomura A, Shimohama S, Zhang J, Montine T, Sayre LM, Smith MA. Hydroxynonenal adducts indicate a role for lipid peroxidation in neocortical and brainstem Lewy bodies in humans. Neuroscience Letters. 319: 25-8. PMID 11814645 DOI: 10.1016/S0304-3940(01)02514-9  1
2001 Zhu X, Castellani RJ, Takeda A, Nunomura A, Atwood CS, Perry G, Smith MA. Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: the 'two hit' hypothesis. Mechanisms of Ageing and Development. 123: 39-46. PMID 11640950 DOI: 10.1016/S0047-6374(01)00342-6  1
2001 Castellani RJ, Harris PL, Sayre LM, Fujii J, Taniguchi N, Vitek MP, Founds H, Atwood CS, Perry G, Smith MA. Active glycation in neurofibrillary pathology of Alzheimer disease: N(epsilon)-(carboxymethyl) lysine and hexitol-lysine. Free Radical Biology & Medicine. 31: 175-80. PMID 11440829 DOI: 10.1016/S0891-5849(01)00570-6  1
2001 Zhou F, Zhu X, Castellani RJ, Stimmelmayr R, Perry G, Smith MA, Drew KL. Hibernation, a model of neuroprotection. The American Journal of Pathology. 158: 2145-51. PMID 11395392 DOI: 10.1016/S0002-9440(10)64686-X  1
2001 Raina AK, Hochman A, Zhu X, Rottkamp CA, Nunomura A, Siedlak SL, Boux H, Castellani RJ, Perry G, Smith MA. Abortive apoptosis in Alzheimer's disease. Acta Neuropathologica. 101: 305-10. PMID 11355301  1
2000 Castellani RJ, Harris PL, Lecroisey A, Izadi-Pruneyre N, Wandersman C, Perry G, Smith MA. Evidence for a novel heme-binding protein, HasAh, in Alzheimer disease. Antioxidants & Redox Signaling. 2: 137-42. PMID 11232594  1
2000 Castellani RJ, Siedlak SL, Perry G, Smith MA. Sequestration of iron by Lewy bodies in Parkinson's disease. Acta Neuropathologica. 100: 111-4. PMID 10963356  1
2000 Rastegar DA, Castellani RJ. A 78-year-old woman with leg pain and weakness. The American Journal of the Medical Sciences. 319: 404-10. PMID 10875298  1
1999 Castellani RJ, Perry G, Brenner DS, Smith MA. Alexander disease: Alzheimer disease of the developing brain? Alzheimer Disease and Associated Disorders. 13: 232-5. PMID 10609673  1
1999 Castellani RJ, Smith MA, Nunomura A, Harris PL, Perry G. Is increased redox-active iron in Alzheimer disease a failure of the copper-binding protein ceruloplasmin? Free Radical Biology & Medicine. 26: 1508-12. PMID 10401616 DOI: 10.1016/S0891-5849(99)00016-7  1
1999 Brat DJ, James CD, Jedlicka AE, Connolly DC, Chang E, Castellani RJ, Schmid M, Schiller M, Carson DA, Burger PC. Molecular genetic alterations in radiation-induced astrocytomas. The American Journal of Pathology. 154: 1431-8. PMID 10329596 DOI: 10.1016/S0002-9440(10)65397-7  1
1998 Perry G, Castellani RJ, Hirai K, Smith MA. Reactive Oxygen Species Mediate Cellular Damage in Alzheimer Disease. Journal of Alzheimer's Disease : Jad. 1: 45-55. PMID 12214011  1
1998 Smith MA, Vasák M, Knipp M, Castellani RJ, Perry G. Dimethylargininase, a nitric oxide regulatory protein, in Alzheimer disease. Free Radical Biology & Medicine. 25: 898-902. PMID 9840734 DOI: 10.1016/S0891-5849(98)00119-1  1
1998 Zagardo MT, Castellani RJ, Rees JH, Rothman MI, Zoarski GH. Radiologic and pathologic findings of intracerebral schwannoma. Ajnr. American Journal of Neuroradiology. 19: 1290-3. PMID 9726470  1
1998 Castellani RJ, Perry G, Harris PL, Cohen ML, Sayre LM, Salomon RG, Smith MA. Advanced lipid peroxidation end-products in Alexander's disease. Brain Research. 787: 15-8. PMID 9518535 DOI: 10.1016/S0006-8993(97)01224-9  1
1997 Drachenberg CB, Ioffe OB, Castellani RJ, Papadimitriou JC. Nuclear bcl-2 staining in tumors. American Journal of Clinical Pathology. 108: 479. PMID 9322602  1
1997 Castellani RJ, Perry G, Harris PL, Monnier VM, Cohen ML, Smith MA. Advanced glycation modification of Rosenthal fibers in patients with Alexander disease. Neuroscience Letters. 231: 79-82. PMID 9291145 DOI: 10.1016/S0304-3940(97)00521-1  1
1997 Zagardo MT, Castellani RJ, Zoarski GH, Bauserman SC. Granulomatous amebic encephalitis caused by leptomyxid amebae in an HIV-infected patient. Ajnr. American Journal of Neuroradiology. 18: 903-8. PMID 9159368  1
1997 Castellani RJ, Parchi P, Madoff L, Gambetti P, McKeever P. Biopsy diagnosis of Creutzfeldt-Jakob disease by western blot: a case report. Human Pathology. 28: 623-6. PMID 9158712 DOI: 10.1016/S0046-8177(97)90086-1  1
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