| Year |
Citation |
Score |
| 2015 |
Parsons WH, Calvo RR, Cheung W, Lee YK, Patel S, Liu J, Youngman MA, Dax SL, Stone D, Qin N, Hutchinson T, Lubin ML, Zhang SP, Finley M, Liu Y, et al. Benzo[d]imidazole Transient Receptor Potential Vanilloid 1 Antagonists for the Treatment of Pain: Discovery of trans-2-(2-{2-[2-(4-Trifluoromethyl-phenyl)-vinyl]-1H-benzimidazol-5-yl}-phenyl)-propan-2-ol (Mavatrep). Journal of Medicinal Chemistry. 58: 3859-74. PMID 25850459 DOI: 10.1021/acs.jmedchem.5b00132 |
0.542 |
|
| 2014 |
Liu Y. Electrophysiological Studies of Voltage-Gated Sodium Channels Using QPatch HT, an Automated Patch-Clamp System. Current Protocols in Pharmacology. 65: 11.14.1-45. PMID 24934605 DOI: 10.1002/0471141755.ph1114s65 |
0.305 |
|
| 2014 |
Winters MP, Subasinghe N, Wall M, Beck E, Brandt MR, Finley MF, Liu Y, Lubin ML, Neeper MP, Qin N, Flores CM, Sui Z. Discovery and SAR of a novel series of 2,4,5,6-tetrahydrocyclopenta[c]pyrazoles as N-type calcium channel inhibitors. Bioorganic & Medicinal Chemistry Letters. 24: 2057-61. PMID 24726803 DOI: 10.1016/j.bmcl.2014.03.063 |
0.604 |
|
| 2014 |
Winters MP, Subasinghe N, Wall M, Beck E, Brandt MR, Finley MF, Liu Y, Lubin ML, Neeper MP, Qin N, Flores CM, Sui Z. Discovery and SAR of novel tetrahydropyrrolo[3,4-c]pyrazoles as inhibitors of the N-type calcium channel. Bioorganic & Medicinal Chemistry Letters. 24: 2053-6. PMID 24726802 DOI: 10.1016/j.bmcl.2014.03.062 |
0.613 |
|
| 2013 |
McComsey DF, Smith-Swintosky VL, Parker MH, Brenneman DE, Malatynska E, White HS, Klein BD, Wilcox KS, Milewski ME, Herb M, Finley MF, Liu Y, Lubin ML, Qin N, Reitz AB, et al. Novel, broad-spectrum anticonvulsants containing a sulfamide group: pharmacological properties of (S)-N-[(6-chloro-2,3-dihydrobenzo[1,4]dioxin-2-yl)methyl]sulfamide (JNJ-26489112). Journal of Medicinal Chemistry. 56: 9019-30. PMID 24205976 DOI: 10.1021/Jm400894U |
0.576 |
|
| 2012 |
Xu XH, Sun HY, Zhang YH, Wu W, Chen KH, Liu Y, Deng CY, Yu XY, Jin MW, Li GR. Allitridi inhibits multiple cardiac potassium channels expressed in HEK 293 cells. Plos One. 7: e51550. PMID 23272117 DOI: 10.1371/Journal.Pone.0051550 |
0.316 |
|
| 2011 |
Liu Y, Beck EJ, Flores CM. Validation of a patch clamp screening protocol that simultaneously measures compound activity in multiple states of the voltage-gated sodium channel Nav1.2. Assay and Drug Development Technologies. 9: 628-34. PMID 21675872 DOI: 10.1089/adt.2011.0375 |
0.326 |
|
| 2010 |
Finley MF, Lubin ML, Neeper MP, Beck E, Liu Y, Flores CM, Qin N. An integrated multiassay approach to the discovery of small-molecule N-type voltage-gated calcium channel antagonists. Assay and Drug Development Technologies. 8: 685-94. PMID 21050074 DOI: 10.1089/adt.2010.0311 |
0.612 |
|
| 2009 |
Parker MH, Smith-Swintosky VL, McComsey DF, Huang Y, Brenneman D, Klein B, Malatynska E, White HS, Milewski ME, Herb M, Finley MF, Liu Y, Lubin ML, Qin N, Iannucci R, et al. Novel, broad-spectrum anticonvulsants containing a sulfamide group: advancement of N-((benzo[b]thien-3-yl)methyl)sulfamide (JNJ-26990990) into human clinical studies. Journal of Medicinal Chemistry. 52: 7528-36. PMID 19388676 DOI: 10.1021/Jm801432R |
0.561 |
|
| 2009 |
Mathes C, Friis S, Finley M, Liu Y. QPatch: the missing link between HTS and ion channel drug discovery. Combinatorial Chemistry & High Throughput Screening. 12: 78-95. PMID 19149494 DOI: 10.2174/138620709787047948 |
0.632 |
|
| 2007 |
Krafte DS, Chapman M, Marron B, Atkinson R, Liu Y, Ye F, Curran M, Kort M, Jarvis MF. Block of Nav1.8 by small molecules. Channels (Austin, Tex.). 1: 152-3. PMID 18690030 DOI: 10.4161/chan.4760 |
0.311 |
|
| 1994 |
Dilger JP, Vidal AM, Mody HI, Liu Y. Evidence for direct actions of general anesthetics on an ion channel protein. A new look at a unified mechanism of action. Anesthesiology. 81: 431-42. PMID 7519836 DOI: 10.1097/00000542-199408000-00022 |
0.703 |
|
| 1993 |
Liu Y, Dilger JP. Application of the one- and two-dimensional Ising models to studies of cooperativity between ion channels. Biophysical Journal. 64: 26-35. PMID 7679298 DOI: 10.1016/S0006-3495(93)81337-7 |
0.637 |
|
| 1993 |
Liu Y, Dilger JP. Decamethonium is a partial agonist at the nicotinic acetylcholine receptor. Synapse (New York, N.Y.). 13: 57-62. PMID 7678947 DOI: 10.1002/syn.890130108 |
0.654 |
|
| 1992 |
Dilger JP, Liu Y. Desensitization of acetylcholine receptors in BC3H-1 cells. Pflã¼Gers Archiv : European Journal of Physiology. 420: 479-85. PMID 1614820 DOI: 10.1007/BF00374622 |
0.681 |
|
| 1991 |
Dilger JP, Brett RS, Poppers DM, Liu Y. The temperature dependence of some kinetic and conductance properties of acetylcholine receptor channels. Biochimica Et Biophysica Acta. 1063: 253-8. PMID 2012822 DOI: 10.1016/0005-2736(91)90379-M |
0.662 |
|
| 1991 |
Liu Y, Dilger JP. Opening rate of acetylcholine receptor channels. Biophysical Journal. 60: 424-32. PMID 1717017 DOI: 10.1016/S0006-3495(91)82068-9 |
0.704 |
|
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