Year |
Citation |
Score |
2020 |
Foliaki ST, Groveman BR, Yuan J, Walters R, Zhang S, Tesar P, Zou W, Haigh CL. Pathogenic Prion Protein Isoforms Are Not Present in Cerebral Organoids Generated from Asymptomatic Donors Carrying the E200K Mutation Associated with Familial Prion Disease. Pathogens (Basel, Switzerland). 9. PMID 32570796 DOI: 10.3390/Pathogens9060482 |
0.371 |
|
2020 |
Carroll JA, Groveman BR, Williams K, Moore R, Race B, Haigh CL. Prion protein N1 cleavage peptides stimulate microglial interaction with surrounding cells. Scientific Reports. 10: 6654. PMID 32313035 DOI: 10.1038/s41598-020-63472-z |
0.354 |
|
2020 |
Groveman BR, Walters R, Haigh CL. Using our mini-brains: cerebral organoids as an improved cellular model for human prion disease. Neural Regeneration Research. 15: 1019-1020. PMID 31823872 DOI: 10.4103/1673-5374.270300 |
0.319 |
|
2019 |
Groveman BR, Foliaki ST, Orru CD, Zanusso G, Carroll JA, Race B, Haigh CL. Sporadic Creutzfeldt-Jakob disease prion infection of human cerebral organoids. Acta Neuropathologica Communications. 7: 12. PMID 31196223 DOI: 10.1186/s40478-019-0742-2 |
0.393 |
|
2019 |
Haigh C. Doubling-down on prion protein function in Alzheimer’s disease Science Translational Medicine. 11: eaay3567. DOI: 10.1126/scitranslmed.aay3567 |
0.406 |
|
2018 |
Collins SJ, Tumpach C, Groveman BR, Drew SC, Haigh CL. Prion protein cleavage fragments regulate adult neural stem cell quiescence through redox modulation of mitochondrial fission and SOD2 expression. Cellular and Molecular Life Sciences : Cmls. PMID 29574582 DOI: 10.1007/s00018-018-2790-3 |
0.38 |
|
2017 |
Haigh CL. Cellular Analysis of Adult Neural Stem Cells for Investigating Prion Biology. Methods in Molecular Biology (Clifton, N.J.). 1658: 133-145. PMID 28861788 DOI: 10.1007/978-1-4939-7244-9_11 |
0.319 |
|
2016 |
Collins SJ, Haigh CL. Simplified Murine 3D Neuronal Cultures for Investigating Neuronal Activity and Neurodegeneration. Cell Biochemistry and Biophysics. PMID 27796787 DOI: 10.1007/s12013-016-0768-z |
0.325 |
|
2016 |
Haigh CL, Tumpach C, Collins SJ, Drew SC. A 2-Substituted 8-Hydroxyquinoline Stimulates Neural Stem Cell Proliferation by Modulating ROS Signalling. Cell Biochemistry and Biophysics. PMID 27329646 DOI: 10.1007/s12013-016-0747-4 |
0.316 |
|
2016 |
Haigh CL, Collins SJ. Endoproteolytic cleavage as a molecular switch regulating and diversifying prion protein function. Neural Regeneration Research. 11: 238-9. PMID 27073372 DOI: 10.4103/1673-5374.177726 |
0.379 |
|
2015 |
Haigh CL, Tumpach C, Drew SC, Collins SJ. The Prion Protein N1 and N2 Cleavage Fragments Bind to Phosphatidylserine and Phosphatidic Acid; Relevance to Stress-Protection Responses. Plos One. 10: e0134680. PMID 26252007 DOI: 10.1371/journal.pone.0134680 |
0.326 |
|
2015 |
Mital M, Wezynfeld NE, Frączyk T, Wiloch MZ, Wawrzyniak UE, Bonna A, Tumpach C, Barnham KJ, Haigh CL, Bal W, Drew SC. A Functional Role for Aβ in Metal Homeostasis? N-Truncation and High-Affinity Copper Binding. Angewandte Chemie (International Ed. in English). 54: 10460-4. PMID 26178596 DOI: 10.1002/anie.201502644 |
0.32 |
|
2015 |
Haigh CL, Drew SC. Cavitation during the protein misfolding cyclic amplification (PMCA) method--The trigger for de novo prion generation? Biochemical and Biophysical Research Communications. 461: 494-500. PMID 25892519 DOI: 10.1016/j.bbrc.2015.04.048 |
0.367 |
|
2015 |
Collins SJ, Tumpach C, Li QX, Lewis V, Ryan TM, Roberts B, Drew SC, Lawson VA, Haigh CL. The prion protein regulates beta-amyloid-mediated self-renewal of neural stem cells in vitro. Stem Cell Research & Therapy. 6: 60. PMID 25884827 DOI: 10.1186/s13287-015-0067-4 |
0.356 |
|
2015 |
Haigh CL, McGlade AR, Collins SJ. MEK1 transduces the prion protein N2 fragment antioxidant effects. Cellular and Molecular Life Sciences : Cmls. 72: 1613-29. PMID 25391659 DOI: 10.1007/s00018-014-1777-y |
0.434 |
|
2014 |
Le Brun AP, Haigh CL, Drew SC, James M, Boland MP, Collins SJ. Neutron reflectometry studies define prion protein N-terminal peptide membrane binding. Biophysical Journal. 107: 2313-24. PMID 25418300 DOI: 10.1016/j.bpj.2014.09.027 |
0.306 |
|
2014 |
Haigh CL, Lawson VA, Drew SC. Blood vessel cell death during prion disease: implications for disease management and infection control. Experimental Hematology. 42: 939-40. PMID 25038450 DOI: 10.1016/j.exphem.2014.06.009 |
0.336 |
|
2014 |
Haigh C, Collins S. Oxidative Modulation of Neural Stem Cell Growth by Prion Protein Cleavage Fragments Free Radical Biology and Medicine. 76: S24. DOI: 10.1016/J.FREERADBIOMED.2014.10.476 |
0.336 |
|
2013 |
Sinclair L, Lewis V, Collins SJ, Haigh CL. Cytosolic caspases mediate mislocalised SOD2 depletion in an in vitro model of chronic prion infection. Disease Models & Mechanisms. 6: 952-63. PMID 23580200 DOI: 10.1242/dmm.010678 |
0.382 |
|
2012 |
Lewis V, Haigh CL, Masters CL, Hill AF, Lawson VA, Collins SJ. Prion subcellular fractionation reveals infectivity spectrum, with a high titre-low PrPres level disparity. Molecular Neurodegeneration. 7: 18. PMID 22534096 DOI: 10.1186/1750-1326-7-18 |
0.358 |
|
2012 |
Karas JA, Boland M, Haigh C, Johanssen V, Hill A, Barnham K, Collins S, Scanlon D. Microwave synthesis of prion protein fragments up to 111 amino acids in length generates biologically active peptides International Journal of Peptide Research and Therapeutics. 18: 21-29. DOI: 10.1007/s10989-011-9275-7 |
0.31 |
|
2011 |
Haigh CL, McGlade AR, Lewis V, Masters CL, Lawson VA, Collins SJ. Acute exposure to prion infection induces transient oxidative stress progressing to be cumulatively deleterious with chronic propagation in vitro. Free Radical Biology & Medicine. 51: 594-608. PMID 21466851 DOI: 10.1016/J.Freeradbiomed.2011.03.035 |
0.422 |
|
2011 |
Drew SC, Haigh CL, Klemm HM, Masters CL, Collins SJ, Barnham KJ, Lawson VA. Optical imaging detects apoptosis in the brain and peripheral organs of prion-infected mice. Journal of Neuropathology and Experimental Neurology. 70: 143-50. PMID 21343883 DOI: 10.1097/Nen.0B013E3182084A8C |
0.37 |
|
2010 |
Lawson VA, Haigh CL, Roberts B, Kenche VB, Klemm HM, Masters CL, Collins SJ, Barnham KJ, Drew SC. Near-infrared fluorescence imaging of apoptotic neuronal cell death in a live animal model of prion disease. Acs Chemical Neuroscience. 1: 720-7. PMID 22778809 DOI: 10.1021/Cn100068X |
0.356 |
|
2010 |
Boland MP, Hatty CR, Separovic F, Hill AF, Tew DJ, Barnham KJ, Haigh CL, James M, Masters CL, Collins SJ. Anionic phospholipid interactions of the prion protein N terminus are minimally perturbing and not driven solely by the octapeptide repeat domain. The Journal of Biological Chemistry. 285: 32282-92. PMID 20679345 DOI: 10.1074/Jbc.M110.123398 |
0.335 |
|
2010 |
Haigh CL, Marom SY, Collins SJ. Copper, endoproteolytic processing of the prion protein and cell signalling. Frontiers in Bioscience (Landmark Edition). 15: 1086-104. PMID 20515743 DOI: 10.2741/3662 |
0.389 |
|
2009 |
Lewis V, Hill AF, Haigh CL, Klug GM, Masters CL, Lawson VA, Collins SJ. Increased proportions of C1 truncated prion protein protect against cellular M1000 prion infection. Journal of Neuropathology and Experimental Neurology. 68: 1125-35. PMID 19918124 DOI: 10.1097/Nen.0B013E3181B96981 |
0.437 |
|
2009 |
Haigh CL, Lewis VA, Vella LJ, Masters CL, Hill AF, Lawson VA, Collins SJ. PrPC-related signal transduction is influenced by copper, membrane integrity and the alpha cleavage site. Cell Research. 19: 1062-78. PMID 19597535 DOI: 10.1038/Cr.2009.86 |
0.324 |
|
2009 |
Haigh CL, Drew SC, Boland MP, Masters CL, Barnham KJ, Lawson VA, Collins SJ. Dominant roles of the polybasic proline motif and copper in the PrP23-89-mediated stress protection response. Journal of Cell Science. 122: 1518-28. PMID 19383722 DOI: 10.1242/Jcs.043604 |
0.384 |
|
2008 |
Haigh CL, Brown DR. Investigation of PrPC metabolism and function in live cells : methods for studying individual cells and cell populations. Methods in Molecular Biology (Clifton, N.J.). 459: 21-34. PMID 18576145 DOI: 10.1007/978-1-59745-234-2_2 |
0.482 |
|
2007 |
Haigh CL, Wright JA, Brown DR. Regulation of prion protein expression by noncoding regions of the Prnp gene. Journal of Molecular Biology. 368: 915-27. PMID 17376480 DOI: 10.1016/j.jmb.2007.02.086 |
0.578 |
|
2006 |
Haigh CL, Brown DR. Regulation of prion protein expression: a potential site for therapeutic intervention in the transmissible spongiform encephalopathies. International Journal of Biomedical Science : Ijbs. 2: 315-23. PMID 23674999 |
0.448 |
|
2006 |
Cheng F, Lindqvist J, Haigh CL, Brown DR, Mani K. Copper-dependent co-internalization of the prion protein and glypican-1. Journal of Neurochemistry. 98: 1445-57. PMID 16923158 DOI: 10.1111/j.1471-4159.2006.03981.x |
0.502 |
|
2006 |
Haigh CL, Brown DR. Prion protein reduces both oxidative and non-oxidative copper toxicity. Journal of Neurochemistry. 98: 677-89. PMID 16787422 DOI: 10.1111/j.1471-4159.2006.03906.x |
0.513 |
|
2005 |
Haigh CL, Edwards K, Brown DR. Copper binding is the governing determinant of prion protein turnover. Molecular and Cellular Neurosciences. 30: 186-96. PMID 16084105 DOI: 10.1016/j.mcn.2005.07.001 |
0.449 |
|
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