Heath D. Schmidt - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Addiction, Depression, Neural Circuitry, Dopamine, Glutamate, Epigenetics

49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Wimmer ME, Vassoler FM, White SL, Schmidt HD, Sidoli S, Han Y, Garica BA, Pierce RC. Impaired cocaine-induced behavioral plasticity in the male offspring of cocaine-experienced sires. The European Journal of Neuroscience. PMID 30565761 DOI: 10.1111/ejn.14310  1
2018 Hernandez NS, Ige KY, Mietlicki-Baase EG, Molina-Castro GC, Turner CA, Hayes MR, Schmidt HD. Glucagon-like peptide-1 receptor activation in the ventral tegmental area attenuates cocaine seeking in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29497166 DOI: 10.1038/s41386-018-0010-3  0.52
2017 Guercio LA, Hofmann ME, Swinford-Jackson SE, Sigman JS, Wimmer ME, Dell'Acqua ML, Schmidt HD, Pierce RC. A-Kinase Anchoring Protein 150 (AKAP150) Promotes Cocaine Reinstatement by Increasing AMPA Receptor Transmission in the Accumbens Shell. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29317777 DOI: 10.1038/npp.2017.297  1
2017 Hernandez NS, O'Donovan B, Ortinski PI, Schmidt HD. Activation of glucagon-like peptide-1 receptors in the nucleus accumbens attenuates cocaine seeking in rats. Addiction Biology. PMID 29226617 DOI: 10.1111/adb.12583  0.52
2017 Mietlicki-Baase EG, McGrath LE, Koch-Laskowski K, Krawczyk J, Reiner DJ, Pham T, Nguyen CTN, Turner CA, Olivos DR, Wimmer ME, Schmidt HD, Hayes MR. Amylin receptor activation in the ventral tegmental area reduces motivated ingestive behavior. Neuropharmacology. PMID 28552704 DOI: 10.1016/j.neuropharm.2017.05.024  0.52
2016 Van Nest D, Hernandez NS, Kranzler HR, Pierce RC, Schmidt HD. Effects of LY466195, a selective kainate receptor antagonist, on ethanol preference and drinking in rats. Neuroscience Letters. PMID 28013091 DOI: 10.1016/j.neulet.2016.12.050  1
2015 Schmidt HD, Mietlicki-Baase EG, Ige KY, Maurer JJ, Reiner DJ, Zimmer DJ, Van Nest DS, Guercio LA, Wimmer ME, Olivos DR, De Jonghe BC, Hayes MR. Glucagon-Like Peptide-1 Receptor Activation in the Ventral Tegmental Area Decreases the Reinforcing Efficacy of Cocaine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26675243 DOI: 10.1038/npp.2015.362  1
2015 White SL, Ortinski PI, Friedman SH, Zhang L, Neve RL, Kalb RG, Schmidt HD, Pierce RC. A Critical Role for the GluA1 Accessory Protein, SAP97, in Cocaine Seeking. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26149358 DOI: 10.1038/npp.2015.199  1
2015 White SL, Vassoler FM, Schmidt HD, Pierce RC, Wimmer ME. Enhanced anxiety in the male offspring of sires that self-administered cocaine. Addiction Biology. PMID 25923597 DOI: 10.1111/adb.12258  1
2015 Ortinski PI, Briand LA, Pierce RC, Schmidt HD. Cocaine-seeking is associated with PKC-dependent reduction of excitatory signaling in accumbens shell D2 dopamine receptor-expressing neurons. Neuropharmacology. 92: 80-9. PMID 25596492 DOI: 10.1016/j.neuropharm.2015.01.002  1
2015 Guercio LA, Schmidt HD, Pierce RC. Deep brain stimulation of the nucleus accumbens shell attenuates cue-induced reinstatement of both cocaine and sucrose seeking in rats. Behavioural Brain Research. 281: 125-30. PMID 25529183 DOI: 10.1016/j.bbr.2014.12.025  1
2015 Schmidt HD, Kimmey BA, Arreola AC, Pierce RC. Group I metabotropic glutamate receptor-mediated activation of PKC gamma in the nucleus accumbens core promotes the reinstatement of cocaine seeking. Addiction Biology. 20: 285-96. PMID 24506432 DOI: 10.1111/adb.12122  1
2014 Schmidt HD, McFarland KN, Darnell SB, Huizenga MN, Sangrey GR, Cha JH, Pierce RC, Sadri-Vakili G. ADAR2-dependent GluA2 editing regulates cocaine seeking. Molecular Psychiatry. PMID 25349168 DOI: 10.1038/mp.2014.134  1
2014 Lee AM, Arreola AC, Kimmey BA, Schmidt HD. Administration of the nicotinic acetylcholine receptor agonists ABT-089 and ABT-107 attenuates the reinstatement of nicotine-seeking behavior in rats. Behavioural Brain Research. 274: 168-75. PMID 25128791 DOI: 10.1016/j.bbr.2014.08.016  1
2014 Rasakham K, Schmidt HD, Kay K, Huizenga MN, Calcagno N, Pierce RC, Spires-Jones TL, Sadri-Vakili G. Synapse density and dendritic complexity are reduced in the prefrontal cortex following seven days of forced abstinence from cocaine self-administration. Plos One. 9: e102524. PMID 25072653 DOI: 10.1371/journal.pone.0102524  1
2014 Ashare RL, Schmidt HD. Optimizing treatments for nicotine dependence by increasing cognitive performance during withdrawal. Expert Opinion On Drug Discovery. 9: 579-94. PMID 24707983 DOI: 10.1517/17460441.2014.908180  1
2014 Kimmey BA, Rupprecht LE, Hayes MR, Schmidt HD. Donepezil, an acetylcholinesterase inhibitor, attenuates nicotine self-administration and reinstatement of nicotine seeking in rats. Addiction Biology. 19: 539-51. PMID 23231479 DOI: 10.1111/adb.12014  1
2013 Vassoler FM, White SL, Hopkins TJ, Guercio LA, Espallergues J, Berton O, Schmidt HD, Pierce RC. Deep brain stimulation of the nucleus accumbens shell attenuates cocaine reinstatement through local and antidromic activation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 14446-54. PMID 24005296 DOI: 10.1523/JNEUROSCI.4804-12.2013  1
2013 Schmidt HD, Schassburger RL, Guercio LA, Pierce RC. Stimulation of mGluR5 in the accumbens shell promotes cocaine seeking by activating PKC gamma. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 14160-9. PMID 23986250 DOI: 10.1523/JNEUROSCI.2284-13.2013  1
2013 Mietlicki-Baase EG, Rupprecht LE, Olivos DR, Zimmer DJ, Alter MD, Pierce RC, Schmidt HD, Hayes MR. Amylin receptor signaling in the ventral tegmental area is physiologically relevant for the control of food intake. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 1685-97. PMID 23474592 DOI: 10.1038/npp.2013.66  1
2013 Schmidt HD, McGinty JF, West AE, Sadri-Vakili G. Epigenetics and psychostimulant addiction. Cold Spring Harbor Perspectives in Medicine. 3: a012047. PMID 23359110 DOI: 10.1101/cshperspect.a012047  1
2013 White SL, Schmidt HD, Vassoler FM, Pierce RC. Acute cocaine increases phosphorylation of CaMKII and GluA1 in the dorsolateral striatum of drug naïve rats, but not cocaine-experienced rats. Neuroscience Letters. 537: 71-6. PMID 23352852 DOI: 10.1016/j.neulet.2013.01.017  1
2013 Vassoler FM, White SL, Schmidt HD, Sadri-Vakili G, Pierce RC. Epigenetic inheritance of a cocaine-resistance phenotype. Nature Neuroscience. 16: 42-7. PMID 23242310 DOI: 10.1038/nn.3280  1
2013 Schmidt HD, Pierce RC. The Role of Glutamate Receptors in Addiction Biological Research On Addiction. 241-250. DOI: 10.1016/B978-0-12-398335-0.00025-X  1
2012 Hopkins TJ, Rupprecht LE, Hayes MR, Blendy JA, Schmidt HD. Galantamine, an acetylcholinesterase inhibitor and positive allosteric modulator of nicotinic acetylcholine receptors, attenuates nicotine taking and seeking in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 2310-21. PMID 22669169 DOI: 10.1038/npp.2012.83  1
2012 Schmidt HD, Sangrey GR, Darnell SB, Schassburger RL, Cha JH, Pierce RC, Sadri-Vakili G. Increased brain-derived neurotrophic factor (BDNF) expression in the ventral tegmental area during cocaine abstinence is associated with increased histone acetylation at BDNF exon I-containing promoters. Journal of Neurochemistry. 120: 202-9. PMID 22043863 DOI: 10.1111/j.1471-4159.2011.07571.x  1
2011 Chen YI, Famous K, Xu H, Choi JK, Mandeville JB, Schmidt HD, Pierce RC, Jenkins BG. Cocaine self-administration leads to alterations in temporal responses to cocaine challenge in limbic and motor circuitry. The European Journal of Neuroscience. 34: 800-15. PMID 21896062 DOI: 10.1111/j.1460-9568.2011.07806.x  1
2011 Schmidt HD, Shelton RC, Duman RS. Functional biomarkers of depression: diagnosis, treatment, and pathophysiology. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 2375-94. PMID 21814182 DOI: 10.1038/npp.2011.151  1
2011 Yee J, Famous KR, Hopkins TJ, McMullen MC, Pierce RC, Schmidt HD. Muscarinic acetylcholine receptors in the nucleus accumbens core and shell contribute to cocaine priming-induced reinstatement of drug seeking. European Journal of Pharmacology. 650: 596-604. PMID 21034738 DOI: 10.1016/j.ejphar.2010.10.045  1
2010 Duric V, Banasr M, Licznerski P, Schmidt HD, Stockmeier CA, Simen AA, Newton SS, Duman RS. A negative regulator of MAP kinase causes depressive behavior. Nature Medicine. 16: 1328-32. PMID 20953200 DOI: 10.1038/nm.2219  1
2010 Sadri-Vakili G, Kumaresan V, Schmidt HD, Famous KR, Chawla P, Vassoler FM, Overland RP, Xia E, Bass CE, Terwilliger EF, Pierce RC, Cha JH. Cocaine-induced chromatin remodeling increases brain-derived neurotrophic factor transcription in the rat medial prefrontal cortex, which alters the reinforcing efficacy of cocaine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 11735-44. PMID 20810894 DOI: 10.1523/JNEUROSCI.2328-10.2010  1
2010 Schmidt HD, Duman RS. Peripheral BDNF produces antidepressant-like effects in cellular and behavioral models. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 2378-91. PMID 20686454 DOI: 10.1038/npp.2010.114  1
2010 Schmidt HD, Pierce RC. Cocaine-induced neuroadaptations in glutamate transmission: potential therapeutic targets for craving and addiction. Annals of the New York Academy of Sciences. 1187: 35-75. PMID 20201846 DOI: 10.1111/j.1749-6632.2009.05144.x  1
2009 Schmidt HD, Famous KR, Pierce RC. The limbic circuitry underlying cocaine seeking encompasses the PPTg/LDT. The European Journal of Neuroscience. 30: 1358-69. PMID 19788581 DOI: 10.1111/j.1460-9568.2009.06904.x  1
2009 Kumaresan V, Yuan M, Yee J, Famous KR, Anderson SM, Schmidt HD, Pierce RC. Metabotropic glutamate receptor 5 (mGluR5) antagonists attenuate cocaine priming- and cue-induced reinstatement of cocaine seeking. Behavioural Brain Research. 202: 238-44. PMID 19463707 DOI: 10.1016/j.bbr.2009.03.039  1
2008 Schmidt HD, Banasr M, Duman RS. Future Antidepressant Targets: Neurotrophic Factors and Related Signaling Cascades. Drug Discovery Today. Therapeutic Strategies. 5: 151-156. PMID 19802372 DOI: 10.1016/j.ddstr.2008.10.003  1
2008 Famous KR, Kumaresan V, Sadri-Vakili G, Schmidt HD, Mierke DF, Cha JH, Pierce RC. Phosphorylation-dependent trafficking of GluR2-containing AMPA receptors in the nucleus accumbens plays a critical role in the reinstatement of cocaine seeking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 11061-70. PMID 18945913 DOI: 10.1523/JNEUROSCI.1221-08.2008  1
2008 Vassoler FM, Schmidt HD, Gerard ME, Famous KR, Ciraulo DA, Kornetsky C, Knapp CM, Pierce RC. Deep brain stimulation of the nucleus accumbens shell attenuates cocaine priming-induced reinstatement of drug seeking in rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 8735-9. PMID 18753374 DOI: 10.1523/JNEUROSCI.5277-07.2008  1
2008 Anderson SM, Famous KR, Sadri-Vakili G, Kumaresan V, Schmidt HD, Bass CE, Terwilliger EF, Cha JH, Pierce RC. CaMKII: a biochemical bridge linking accumbens dopamine and glutamate systems in cocaine seeking. Nature Neuroscience. 11: 344-53. PMID 18278040 DOI: 10.1038/nn2054  1
2008 Anderson SM, Famous KR, Sadri-Vakili G, Kumaresan V, Schmidt HD, Bass CE, Terwilliger EF, Cha JHJ, Pierce RC. CaMKII: A biochemical bridge linking accumbens dopamine and glutamate systems in cocaine seeking (Nature Neuroscience (2008) 11, 344-353) Nature Neuroscience. 11: 617. DOI: 10.1038/nn0508-617  1
2007 Schmidt HD, Duman RS. The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior. Behavioural Pharmacology. 18: 391-418. PMID 17762509 DOI: 10.1097/FBP.0b013e3282ee2aa8  1
2007 Famous KR, Schmidt HD, Pierce RC. When administered into the nucleus accumbens core or shell, the NMDA receptor antagonist AP-5 reinstates cocaine-seeking behavior in the rat. Neuroscience Letters. 420: 169-73. PMID 17513051 DOI: 10.1016/j.neulet.2007.04.063  1
2006 Schmidt HD, Pierce RC. Systemic administration of a dopamine, but not a serotonin or norepinephrine, transporter inhibitor reinstates cocaine seeking in the rat. Behavioural Brain Research. 175: 189-94. PMID 16978714 DOI: 10.1016/j.bbr.2006.08.009  1
2006 Schmidt HD, Pierce RC. Cooperative activation of D1-like and D2-like dopamine receptors in the nucleus accumbens shell is required for the reinstatement of cocaine-seeking behavior in the rat. Neuroscience. 142: 451-61. PMID 16844308 DOI: 10.1016/j.neuroscience.2006.06.004  1
2006 Howe ML, Mehmud ZF, Saha S, Buratovich M, Stutius EA, Schmidt HD, Lenon AL, Reddicks C, Ivanov GS, Przyborski SA, Ozer JS. Transcription Factor IIA tau is associated with undifferentiated cells and its gene expression is repressed in primary neurons at the chromatin level in vivo. Stem Cells and Development. 15: 175-90. PMID 16646664 DOI: 10.1089/scd.2006.15.175  1
2006 Schmidt HD, Anderson SM, Pierce RC. Stimulation of D1-like or D2 dopamine receptors in the shell, but not the core, of the nucleus accumbens reinstates cocaine-seeking behaviour in the rat. The European Journal of Neuroscience. 23: 219-28. PMID 16420431 DOI: 10.1111/j.1460-9568.2005.04524.x  1
2006 Anderson SM, Schmidt HD, Pierce RC. Administration of the D2 dopamine receptor antagonist sulpiride into the shell, but not the core, of the nucleus accumbens attenuates cocaine priming-induced reinstatement of drug seeking. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 1452-61. PMID 16205775 DOI: 10.1038/sj.npp.1300922  1
2005 Schmidt HD, Anderson SM, Famous KR, Kumaresan V, Pierce RC. Anatomy and pharmacology of cocaine priming-induced reinstatement of drug seeking. European Journal of Pharmacology. 526: 65-76. PMID 16321382 DOI: 10.1016/j.ejphar.2005.09.068  1
2004 Licata SC, Schmidt HD, Pierce RC. Suppressing calcium/calmodulin-dependent protein kinase II activity in the ventral tegmental area enhances the acute behavioural response to cocaine but attenuates the initiation of cocaine-induced behavioural sensitization in rats. The European Journal of Neuroscience. 19: 405-14. PMID 14725635 DOI: 10.1111/j.0953-816X.2003.03110.x  1
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