Ashley Lepack - Publications

Affiliations: 
2015- Pharmacology & Systems Therapeutics Icahn School of Medicine at Mount Sinai, New York, NY, United States 

18 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Banasr M, Codeluppi S, Xu M, Bansal Y, Lepack A, Duric V, Chow M, Muir J, Bagot R, Licznerski P, Wilber S, Sanacora G, Sibille E, Duman R, Pittenger C. Prefrontal Cortex Astroglia Modulate Anhedonia-like Behavior. Research Square. PMID 37461693 DOI: 10.21203/rs.3.rs-3093428/v1  0.301
2023 Al-Kachak A, Fulton SL, Farrelly LA, Lepack AE, Bastle RM, Kong L, Cathomas F, Newman EL, Menard C, Ramakrishnan A, Chan JC, Safovich P, Lyu Y, Covington HE, Shen L, et al. Histone H3 serotonylation dynamics in dorsal raphe nucleus contribute to stress-induced gene expression and behavior. Biorxiv : the Preprint Server For Biology. PMID 37205414 DOI: 10.1101/2023.05.04.539464  0.707
2023 Fulton SL, Bendl J, Gameiro-Ros I, Fullard JF, Al-Kachak A, Lepack AE, Stewart AF, Singh S, Poller WC, Bastle RM, Hauberg ME, Fakira AK, Chen M, Cuttoli RD, Cathomas F, et al. ZBTB7A regulates MDD-specific chromatin signatures and astrocyte-mediated stress vulnerability in orbitofrontal cortex. Biorxiv : the Preprint Server For Biology. PMID 37205394 DOI: 10.1101/2023.05.04.539425  0.745
2023 Finkin-Groner E, Al-Kachak A, Agustinus A, Bastle R, Lepack A, Lyu Y, Maze I, David Y. Flexible and site-specific manipulation of histones in live animals. Biorxiv : the Preprint Server For Biology. PMID 36993231 DOI: 10.1101/2023.03.19.533378  0.717
2023 Stewart AF, Lepack AL, Fulton SL, Safovich P, Maze I. Histone H3 dopaminylation in nucleus accumbens, but not medial prefrontal cortex, contributes to cocaine-seeking following prolonged abstinence. Molecular and Cellular Neurosciences. 125: 103824. PMID 36842545 DOI: 10.1016/j.mcn.2023.103824  0.667
2022 Fulton SL, Wenderski W, Lepack AE, Eagle AL, Fanutza T, Bastle RM, Ramakrishnan A, Hays EC, Neal A, Bendl J, Farrelly LA, Al-Kachak A, Lyu Y, Cetin B, Chan JC, et al. Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome. Nature Communications. 13: 6384. PMID 36289231 DOI: 10.1038/s41467-022-34200-0  0.68
2022 Fulton SL, Mitra S, Lepack AE, Martin JA, Stewart AF, Converse J, Hochstetler M, Dietz DM, Maze I. Histone H3 dopaminylation in ventral tegmental area underlies heroin-induced transcriptional and behavioral plasticity in male rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 35094023 DOI: 10.1038/s41386-022-01279-4  0.716
2020 Lepack AE, Werner CT, Stewart AF, Fulton SL, Zhong P, Farrelly LA, Smith ACW, Ramakrishnan A, Lyu Y, Bastle RM, Martin JA, Mitra S, O'Connor RM, Wang ZJ, Molina H, et al. Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking. Science (New York, N.Y.). 368: 197-201. PMID 32273471 DOI: 10.1126/Science.Aaw8806  0.746
2019 Werner CT, Mitra S, Martin JA, Stewart AF, Lepack AE, Ramakrishnan A, Gobira PH, Wang ZJ, Neve RL, Gancarz AM, Shen L, Maze I, Dietz DM. Ubiquitin-proteasomal regulation of chromatin remodeler INO80 in the nucleus accumbens mediates persistent cocaine craving. Science Advances. 5: eaay0351. PMID 31633032 DOI: 10.1126/Sciadv.Aay0351  0.647
2019 Lorsch ZS, Hamilton PJ, Ramakrishnan A, Parise EM, Salery M, Wright WJ, Lepack AE, Mews P, Issler O, McKenzie A, Zhou X, Parise LF, Pirpinias ST, Ortiz Torres I, Kronman HG, et al. Stress resilience is promoted by a Zfp189-driven transcriptional network in prefrontal cortex. Nature Neuroscience. PMID 31427770 DOI: 10.1038/S41593-019-0462-8  0.716
2019 Farrelly LA, Thompson RE, Zhao S, Lepack AE, Lyu Y, Bhanu NV, Zhang B, Loh YE, Ramakrishnan A, Vadodaria KC, Heard KJ, Erikson G, Nakadai T, Bastle RM, Lukasak BJ, et al. Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3. Nature. PMID 30867594 DOI: 10.1038/S41586-019-1024-7  0.774
2018 Heshmati M, Aleyasin H, Menard C, Christoffel DJ, Flanigan ME, Pfau ML, Hodes GE, Lepack AE, Bicks LK, Takahashi A, Chandra R, Turecki G, Lobo MK, Maze I, Golden SA, et al. Cell-type-specific role for nucleus accumbens neuroligin-2 in depression and stress susceptibility. Proceedings of the National Academy of Sciences of the United States of America. PMID 29339486 DOI: 10.1073/Pnas.1719014115  0.676
2018 Lorsch Z, Hamilton P, Lepack A, Mews P, Parise E, Alcantara L, Issler O, Ramakrishnan A, Purushothaman I, Loh YE, McKenzie A, Wang M, Maze I, Zhang B, Shen L, et al. O41. CREB-Zfp189 Interactions Regulate a Resilient-Specific Transcriptional Network in Animal Models of Depression Biological Psychiatry. 83: S125. DOI: 10.1016/J.Biopsych.2018.02.328  0.662
2017 Banasr M, Lepack A, Fee C, Duric V, Maldonado-Aviles J, DiLeone R, Sibille E, Duman RS, Sanacora G. Characterization of GABAergic marker expression in the chronic unpredictable stress model of depression. Chronic Stress (Thousand Oaks, Calif.). 1. PMID 28835932  0.334
2016 Lepack AE, Bagot RC, Peña CJ, Loh YE, Farrelly LA, Lu Y, Powell SK, Lorsch ZS, Issler O, Cates HM, Tamminga CA, Molina H, Shen L, Nestler EJ, Allis CD, et al. Aberrant H3.3 dynamics in NAc promote vulnerability to depressive-like behavior. Proceedings of the National Academy of Sciences of the United States of America. PMID 27791098 DOI: 10.1073/Pnas.1608270113  0.788
2015 Dwyer JM, Maldonado-Avilés JG, Lepack AE, DiLeone RJ, Duman RS. Ribosomal protein S6 kinase 1 signaling in prefrontal cortex controls depressive behavior. Proceedings of the National Academy of Sciences of the United States of America. 112: 6188-93. PMID 25918363 DOI: 10.1073/Pnas.1505289112  0.343
2012 Kang HJ, Voleti B, Hajszan T, Rajkowska G, Stockmeier CA, Licznerski P, Lepack A, Majik MS, Jeong LS, Banasr M, Son H, Duman RS. Decreased expression of synapse-related genes and loss of synapses in major depressive disorder. Nature Medicine. 18: 1413-7. PMID 22885997 DOI: 10.1038/Nm.2886  0.313
2012 Son H, Banasr M, Choi M, Chae SY, Licznerski P, Lee B, Voleti B, Li N, Lepack A, Fournier NM, Lee KR, Lee IY, Kim J, Kim JH, Kim YH, et al. Neuritin produces antidepressant actions and blocks the neuronal and behavioral deficits caused by chronic stress. Proceedings of the National Academy of Sciences of the United States of America. 109: 11378-83. PMID 22733766 DOI: 10.1073/Pnas.1201191109  0.324
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