Saurav R. Seshadri - Publications

Affiliations: 
National Institutes of Health, Bethesda, MD 

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Seshadri S, Faust T, Ishizuka K, Delevich K, Chung Y, Kim SH, Cowles M, Niwa M, Jaaro-Peled H, Tomoda T, Lai C, Anton ES, Li B, Sawa A. Interneuronal DISC1 regulates NRG1-ErbB4 signalling and excitatory-inhibitory synapse formation in the mature cortex. Nature Communications. 6: 10118. PMID 26656849 DOI: 10.1038/ncomms10118  1
2015 Wilker EH, Preis SR, Beiser AS, Wolf PA, Au R, Kloog I, Li W, Schwartz J, Koutrakis P, DeCarli C, Seshadri S, Mittleman MA. Long-term exposure to fine particulate matter, residential proximity to major roads and measures of brain structure. Stroke; a Journal of Cerebral Circulation. 46: 1161-6. PMID 25908455 DOI: 10.1161/STROKEAHA.114.008348  1
2015 van der Lee SJ, Holstege H, Wong TH, Jakobsdottir J, Bis JC, Chouraki V, van Rooij JG, Grove ML, Smith AV, Amin N, Choi SH, Beiser AS, Garcia ME, van IJcken WF, Pijnenburg YA, ... ... Seshadri S, et al. PLD3 variants in population studies. Nature. 520: E2-3. PMID 25832410 DOI: 10.1038/nature14038  1
2015 Kano S, Yuan M, Cardarelli RA, Maegawa G, Higurashi N, Gaval-Cruz M, Wilson AM, Tristan C, Kondo MA, Chen Y, Koga M, Obie C, Ishizuka K, Seshadri S, Srivastava R, et al. Clinical utility of neuronal cells directly converted from fibroblasts of patients for neuropsychiatric disorders: studies of lysosomal storage diseases and channelopathy. Current Molecular Medicine. 15: 138-45. PMID 25732146  1
2015 Desikan RS, Schork AJ, Wang Y, Witoelar A, Sharma M, McEvoy LK, Holland D, Brewer JB, Chen CH, Thompson WK, Harold D, Williams J, Owen MJ, O'Donovan MC, Pericak-Vance MA, ... ... Seshadri S, et al. Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus. Molecular Psychiatry. PMID 25687773 DOI: 10.1038/mp.2015.6  1
2015 Chauhan G, Adams HH, Bis JC, Weinstein G, Yu L, Töglhofer AM, Smith AV, van der Lee SJ, Gottesman RF, Thomson R, Wang J, Yang Q, Niessen WJ, Lopez OL, Becker JT, ... ... Seshadri S, et al. Association of Alzheimer's disease GWAS loci with MRI markers of brain aging. Neurobiology of Aging. 36: 1765.e7-16. PMID 25670335 DOI: 10.1016/j.neurobiolaging.2014.12.028  1
2015 Rannikmäe K, Davies G, Thomson PA, Bevan S, Devan WJ, Falcone GJ, Traylor M, Anderson CD, Battey TW, Radmanesh F, Deka R, Woo JG, Martin LJ, Jimenez-Conde J, Selim M, ... ... Seshadri S, et al. Common variation in COL4A1/COL4A2 is associated with sporadic cerebral small vessel disease. Neurology. 84: 918-26. PMID 25653287 DOI: 10.1212/WNL.0000000000001309  1
2015 Lopez LM, Hill WD, Harris SE, Valdes Hernandez M, Munoz Maniega S, Bastin ME, Bailey E, Smith C, McBride M, McClure J, Graham D, Dominiczak A, Yang Q, Fornage M, Ikram MA, ... ... Seshadri S, et al. Genes from a translational analysis support a multifactorial nature of white matter hyperintensities. Stroke; a Journal of Cerebral Circulation. 46: 341-7. PMID 25586835 DOI: 10.1161/STROKEAHA.114.007649  1
2015 Shahani N, Seshadri S, Jaaro-Peled H, Ishizuka K, Hirota-Tsuyada Y, Wang Q, Koga M, Sedlak TW, Korth C, Brandon NJ, Kamiya A, Subramaniam S, Tomoda T, Sawa A. DISC1 regulates trafficking and processing of APP and Aβ generation. Molecular Psychiatry. 20: 874-9. PMID 25224257 DOI: 10.1038/mp.2014.100  1
2015 Broer L, Buchman AS, Deelen J, Evans DS, Faul JD, Lunetta KL, Sebastiani P, Smith JA, Smith AV, Tanaka T, Yu L, Arnold AM, Aspelund T, Benjamin EJ, De Jager PL, ... ... Seshadri S, et al. GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 70: 110-8. PMID 25199915 DOI: 10.1093/gerona/glu166  1
2014 Kilarski LL, Achterberg S, Devan WJ, Traylor M, Malik R, Lindgren A, Pare G, Sharma P, Slowik A, Thijs V, Walters M, Worrall BB, Sale MM, Algra A, Kappelle LJ, ... ... Seshadri S, et al. Meta-analysis in more than 17,900 cases of ischemic stroke reveals a novel association at 12q24.12. Neurology. 83: 678-85. PMID 25031287 DOI: 10.1212/WNL.0000000000000707  1
2014 Dichgans M, Malik R, König IR, Rosand J, Clarke R, Gretarsdottir S, Thorleifsson G, Mitchell BD, Assimes TL, Levi C, O'Donnell CJ, Fornage M, Thorsteinsdottir U, Psaty BM, Hengstenberg C, ... Seshadri S, et al. Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants. Stroke; a Journal of Cerebral Circulation. 45: 24-36. PMID 24262325 DOI: 10.1161/STROKEAHA.113.002707  1
2014 Hulse KE, Chaung K, Seshadri S, Suh L, Norton JE, Carter RG, Kern RC, Conley DB, Chandra RK, Tan BK, Peters AT, Grammer LC, Harris KE, Torgerson TR, Kato A, et al. Suppressor of cytokine signaling 3 expression is diminished in sinonasal tissues from patients with chronic rhinosinusitis with nasal polyps. The Journal of Allergy and Clinical Immunology. 133: 275-7.e1. PMID 24084073 DOI: 10.1016/j.jaci.2013.08.015  1
2014 Li M, Luo XJ, Rietschel M, Lewis CM, Mattheisen M, Müller-Myhsok B, Jamain S, Leboyer M, Landén M, Thompson PM, Cichon S, Nöthen MM, Schulze TG, Sullivan PF, Bergen SE, ... ... Seshadri S, et al. Allelic differences between Europeans and Chinese for CREB1 SNPs and their implications in gene expression regulation, hippocampal structure and function, and bipolar disorder susceptibility. Molecular Psychiatry. 19: 452-61. PMID 23568192 DOI: 10.1038/mp.2013.37  1
2013 Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, DeStafano AL, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thorton-Wells TA, Jones N, Smith AV, Chouraki V, ... ... Seshadri S, et al. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nature Genetics. 45: 1452-8. PMID 24162737 DOI: 10.1038/ng.2802  1
2013 Rosenquist KJ, Massaro JM, Pencina KM, D'Agostino RB, Beiser A, O'Connor GT, O'Donnell CJ, Wolf PA, Polak JF, Seshadri S, Fox CS. Neck circumference, carotid wall intima-media thickness, and incident stroke. Diabetes Care. 36: e153-4. PMID 23970728 DOI: 10.2337/dc13-0379  1
2013 Seshadri S, Rosati M, Lin DC, Carter RG, Norton JE, Choi AW, Suh L, Kato A, Chandra RK, Harris KE, Chu HW, Peters AT, Tan BK, Conley DB, Grammer LC, et al. Regional differences in the expression of innate host defense molecules in sinonasal mucosa. The Journal of Allergy and Clinical Immunology. 132: 1227-1230.e5. PMID 23895899 DOI: 10.1016/j.jaci.2013.05.042  1
2013 Kondo MA, Tajinda K, Colantuoni C, Hiyama H, Seshadri S, Huang B, Pou S, Furukori K, Hookway C, Jaaro-Peled H, Kano SI, Matsuoka N, Harada K, Ni K, Pevsner J, et al. Unique pharmacological actions of atypical neuroleptic quetiapine: possible role in cell cycle/fate control. Translational Psychiatry. 3: e243. PMID 23549417 DOI: 10.1038/tp.2013.19  1
2013 Seshadri S, Zeledon M, Sawa A. Synapse-specific contributions in the cortical pathology of schizophrenia. Neurobiology of Disease. 53: 26-35. PMID 23336981 DOI: 10.1016/j.nbd.2013.01.009  1
2013 Niwa M, Jaaro-Peled H, Tankou S, Seshadri S, Hikida T, Matsumoto Y, Cascella NG, Kano S, Ozaki N, Nabeshima T, Sawa A. Adolescent stress-induced epigenetic control of dopaminergic neurons via glucocorticoids. Science (New York, N.Y.). 339: 335-9. PMID 23329051 DOI: 10.1126/science.1226931  1
2013 Ma TM, Abazyan S, Abazyan B, Nomura J, Yang C, Seshadri S, Sawa A, Snyder SH, Pletnikov MV. Pathogenic disruption of DISC1-serine racemase binding elicits schizophrenia-like behavior via D-serine depletion. Molecular Psychiatry. 18: 557-67. PMID 22801410 DOI: 10.1038/mp.2012.97  1
2013 Zade D, Beiser A, McGlinchey R, Au R, Seshadri S, Palumbo C, Wolf PA, DeCarli C, Milberg W. Apolipoprotein epsilon 4 allele modifies waist-to-hip ratio effects on cognition and brain structure. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. 22: 119-25. PMID 21835633 DOI: 10.1016/j.jstrokecerebrovasdis.2011.06.020  1
2012 Seshadri S, Lin DC, Rosati M, Carter RG, Norton JE, Suh L, Kato A, Chandra RK, Harris KE, Chu HW, Peters AT, Tan BK, Conley DB, Grammer LC, Kern RC, et al. Reduced expression of antimicrobial PLUNC proteins in nasal polyp tissues of patients with chronic rhinosinusitis. Allergy. 67: 920-8. PMID 22676062 DOI: 10.1111/j.1398-9995.2012.02848.x  1
2011 Debette S, Seshadri S, Beiser A, Au R, Himali JJ, Palumbo C, Wolf PA, DeCarli C. Midlife vascular risk factor exposure accelerates structural brain aging and cognitive decline. Neurology. 77: 461-8. PMID 21810696 DOI: 10.1212/WNL.0b013e318227b227  1
2011 Ishizuka K, Kamiya A, Oh EC, Kanki H, Seshadri S, Robinson JF, Murdoch H, Dunlop AJ, Kubo K, Furukori K, Huang B, Zeledon M, Hayashi-Takagi A, Okano H, Nakajima K, et al. DISC1-dependent switch from progenitor proliferation to migration in the developing cortex. Nature. 473: 92-6. PMID 21471969 DOI: 10.1038/nature09859  1
2011 Ramsey AJ, Milenkovic M, Oliveira AF, Escobedo-Lozoya Y, Seshadri S, Salahpour A, Sawa A, Yasuda R, Caron MG. Impaired NMDA receptor transmission alters striatal synapses and DISC1 protein in an age-dependent manner. Proceedings of the National Academy of Sciences of the United States of America. 108: 5795-800. PMID 21436042 DOI: 10.1073/pnas.1012621108  1
2011 Wang Q, Charych EI, Pulito VL, Lee JB, Graziane NM, Crozier RA, Revilla-Sanchez R, Kelly MP, Dunlop AJ, Murdoch H, Taylor N, Xie Y, Pausch M, Hayashi-Takagi A, Ishizuka K, ... Seshadri S, et al. The psychiatric disease risk factors DISC1 and TNIK interact to regulate synapse composition and function. Molecular Psychiatry. 16: 1006-23. PMID 20838393 DOI: 10.1038/mp.2010.87  1
2010 Kubo K, Tomita K, Uto A, Kuroda K, Seshadri S, Cohen J, Kaibuchi K, Kamiya A, Nakajima K. Migration defects by DISC1 knockdown in C57BL/6, 129X1/SvJ, and ICR strains via in utero gene transfer and virus-mediated RNAi. Biochemical and Biophysical Research Communications. 400: 631-7. PMID 20807500 DOI: 10.1016/j.bbrc.2010.08.117  0.76
2010 Zade D, Beiser A, McGlinchey R, Au R, Seshadri S, Palumbo C, Wolf PA, Decarli C, Milberg W. Interactive effects of apolipoprotein E type 4 genotype and cerebrovascular risk on neuropsychological performance and structural brain changes. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. 19: 261-8. PMID 20471857 DOI: 10.1016/j.jstrokecerebrovasdis.2009.05.001  1
2010 Newman AB, Walter S, Lunetta KL, Garcia ME, Slagboom PE, Christensen K, Arnold AM, Aspelund T, Aulchenko YS, Benjamin EJ, Christiansen L, D'Agostino RB, Fitzpatrick AL, Franceschini N, Glazer NL, ... ... Seshadri S, et al. A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 65: 478-87. PMID 20304771 DOI: 10.1093/gerona/glq028  1
2010 Seshadri S, Kamiya A, Yokota Y, Prikulis I, Kano S, Hayashi-Takagi A, Stanco A, Eom TY, Rao S, Ishizuka K, Wong P, Korth C, Anton ES, Sawa A. Disrupted-in-Schizophrenia-1 expression is regulated by beta-site amyloid precursor protein cleaving enzyme-1-neuregulin cascade. Proceedings of the National Academy of Sciences of the United States of America. 107: 5622-7. PMID 20212127 DOI: 10.1073/pnas.0909284107  1
2010 Niwa M, Kamiya A, Murai R, Kubo K, Gruber AJ, Tomita K, Lu L, Tomisato S, Jaaro-Peled H, Seshadri S, Hiyama H, Huang B, Kohda K, Noda Y, O'Donnell P, et al. Knockdown of DISC1 by in utero gene transfer disturbs postnatal dopaminergic maturation in the frontal cortex and leads to adult behavioral deficits. Neuron. 65: 480-9. PMID 20188653 DOI: 10.1016/j.neuron.2010.01.019  1
2010 Peters AT, Kato A, Zhang N, Conley DB, Suh L, Tancowny B, Carter D, Carr T, Radtke M, Hulse KE, Seshadri S, Chandra R, Grammer LC, Harris KE, Kern R, et al. Evidence for altered activity of the IL-6 pathway in chronic rhinosinusitis with nasal polyps. The Journal of Allergy and Clinical Immunology. 125: 397-403.e10. PMID 20159251 DOI: 10.1016/j.jaci.2009.10.072  1
2010 Hayashi-Takagi A, Takaki M, Graziane N, Seshadri S, Murdoch H, Dunlop AJ, Makino Y, Seshadri AJ, Ishizuka K, Srivastava DP, Xie Z, Baraban JM, Houslay MD, Tomoda T, Brandon NJ, et al. Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1. Nature Neuroscience. 13: 327-32. PMID 20139976 DOI: 10.1038/nn.2487  1
2009 Jaaro-Peled H, Hayashi-Takagi A, Seshadri S, Kamiya A, Brandon NJ, Sawa A. Neurodevelopmental mechanisms of schizophrenia: understanding disturbed postnatal brain maturation through neuregulin-1-ErbB4 and DISC1. Trends in Neurosciences. 32: 485-95. PMID 19712980 DOI: 10.1016/j.tins.2009.05.007  1
2008 Das RR, Seshadri S, Beiser AS, Kelly-Hayes M, Au R, Himali JJ, Kase CS, Benjamin EJ, Polak JF, O'Donnell CJ, Yoshita M, D'Agostino RB, DeCarli C, Wolf PA. Prevalence and correlates of silent cerebral infarcts in the Framingham offspring study. Stroke; a Journal of Cerebral Circulation. 39: 2929-35. PMID 18583555 DOI: 10.1161/STROKEAHA.108.516575  1
2008 Seshadri S, Wolf PA, Beiser AS, Selhub J, Au R, Jacques PF, Yoshita M, Rosenberg IH, D'Agostino RB, DeCarli C. Association of plasma total homocysteine levels with subclinical brain injury: cerebral volumes, white matter hyperintensity, and silent brain infarcts at volumetric magnetic resonance imaging in the Framingham Offspring Study. Archives of Neurology. 65: 642-9. PMID 18474741 DOI: 10.1001/archneur.65.5.642  1
2008 Yang C, Mwaikambo BR, Zhu T, Gagnon C, Lafleur J, Seshadri S, Lachapelle P, Lavoie JC, Chemtob S, Hardy P. Lymphocytic microparticles inhibit angiogenesis by stimulating oxidative stress and negatively regulating VEGF-induced pathways. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 294: R467-76. PMID 18046016 DOI: 10.1152/ajpregu.00432.2007  0.52
2007 Larson MG, Atwood LD, Benjamin EJ, Cupples LA, D'Agostino RB, Fox CS, Govindaraju DR, Guo CY, Heard-Costa NL, Hwang SJ, Murabito JM, Newton-Cheh C, O'Donnell CJ, Seshadri S, Vasan RS, et al. Framingham Heart Study 100K project: genome-wide associations for cardiovascular disease outcomes. Bmc Medical Genetics. 8: S5. PMID 17903304 DOI: 10.1186/1471-2350-8-S1-S5  1
2007 Seshadri S, DeStefano AL, Au R, Massaro JM, Beiser AS, Kelly-Hayes M, Kase CS, D'Agostino RB, Decarli C, Atwood LD, Wolf PA. Genetic correlates of brain aging on MRI and cognitive test measures: a genome-wide association and linkage analysis in the Framingham Study. Bmc Medical Genetics. 8: S15. PMID 17903297 DOI: 10.1186/1471-2350-8-S1-S15  1
2007 Lunetta KL, D'Agostino RB, Karasik D, Benjamin EJ, Guo CY, Govindaraju R, Kiel DP, Kelly-Hayes M, Massaro JM, Pencina MJ, Seshadri S, Murabito JM. Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study. Bmc Medical Genetics. 8: S13. PMID 17903295 DOI: 10.1186/1471-2350-8-S1-S13  1
2007 Cupples LA, Arruda HT, Benjamin EJ, D'Agostino RB, Demissie S, DeStefano AL, Dupuis J, Falls KM, Fox CS, Gottlieb DJ, Govindaraju DR, Guo CY, Heard-Costa NL, Hwang SJ, Kathiresan S, ... ... Seshadri S, et al. The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports. Bmc Medical Genetics. 8: S1. PMID 17903291 DOI: 10.1186/1471-2350-8-S1-S1  1
2007 Hikida T, Jaaro-Peled H, Seshadri S, Oishi K, Hookway C, Kong S, Wu D, Xue R, Andradé M, Tankou S, Mori S, Gallagher M, Ishizuka K, Pletnikov M, Kida S, et al. Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans. Proceedings of the National Academy of Sciences of the United States of America. 104: 14501-6. PMID 17675407 DOI: 10.1073/pnas.0704774104  1
2007 Harper NJ, Gray S, De Groot J, Parker JM, Sadrzadeh N, Schuler C, Schumacher JD, Seshadri S, Smith AE, Steeno GS, Stevenson CL, Taniere R, Wang M, Bennett DB. The design and performance of the exubera pulmonary insulin delivery system. Diabetes Technology & Therapeutics. 9: S16-27. PMID 17563300 DOI: 10.1089/dia.2007.0222  1
2006 Elias MF, Sullivan LM, Elias PK, Vasan RS, D'Agostino RB, Seshadri S, Au R, Wolf PA, Benjamin EJ. Atrial fibrillation is associated with lower cognitive performance in the Framingham offspring men. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. 15: 214-22. PMID 17904078 DOI: 10.1016/j.jstrokecerebrovasdis.2006.05.009  1
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