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George Z. Mentis, Phd - Publications

Affiliations: 
Columbia University, New York, NY 
Area:
Neural Degeneration and Repair, Sensory Physiology, Synapses and Circuits, Motor Systems
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57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Delestrée N, Semizoglou E, Pagiazitis JG, Vukojicic A, Drobac E, Paushkin V, Mentis GZ. Serotonergic dysfunction impairs locomotor coordination in spinal muscular atrophy. Brain : a Journal of Neurology. PMID 37678880 DOI: 10.1093/brain/awad221  0.461
2022 Tisdale S, Van Alstyne M, Simon CM, Mentis GZ, Pellizzoni L. SMN controls neuromuscular junction integrity through U7 snRNP. Cell Reports. 40: 111393. PMID 36130491 DOI: 10.1016/j.celrep.2022.111393  0.353
2022 Chalif JI, Mentis GZ. Normal Development and Pathology of Motoneurons: Anatomy, Electrophysiological Properties, Firing Patterns and Circuit Connectivity. Advances in Neurobiology. 28: 63-85. PMID 36066821 DOI: 10.1007/978-3-031-07167-6_3  0.384
2022 Buettner JM, Kirmann T, Mentis GZ, Hallermann S, Simon CM. Laser microscopy acquisition and analysis of premotor synapses in the murine spinal cord. Star Protocols. 3: 101236. PMID 35300003 DOI: 10.1016/j.xpro.2022.101236  0.467
2022 Chalif JI, Martínez-Silva ML, Pagiazitis JG, Murray AJ, Mentis GZ. Control of mammalian locomotion by ventral spinocerebellar tract neurons. Cell. 185: 328-344.e26. PMID 35063074 DOI: 10.1016/j.cell.2021.12.014  0.377
2021 Riboldi GM, Faravelli I, Kuwajima T, Delestrée N, Dermentzaki G, De Planell-Saguer M, Rinchetti P, Hao LT, Beattie CC, Corti S, Przedborski S, Mentis GZ, Lotti F. Sumoylation regulates the assembly and activity of the SMN complex. Nature Communications. 12: 5040. PMID 34413305 DOI: 10.1038/s41467-021-25272-5  0.407
2021 Van Alstyne M, Tattoli I, Delestrée N, Recinos Y, Workman E, Shihabuddin LS, Zhang C, Mentis GZ, Pellizzoni L. Gain of toxic function by long-term AAV9-mediated SMN overexpression in the sensorimotor circuit. Nature Neuroscience. PMID 33795885 DOI: 10.1038/s41593-021-00827-3  0.393
2021 Kong L, Valdivia DO, Simon CM, Hassinan CW, Delestrée N, Ramos DM, Park JH, Pilato CM, Xu X, Crowder M, Grzyb CC, King ZA, Petrillo M, Swoboda KJ, Davis C, ... ... Mentis GZ, et al. Impaired prenatal motor axon development necessitates early therapeutic intervention in severe SMA. Science Translational Medicine. 13. PMID 33504650 DOI: 10.1126/scitranslmed.abb6871  0.311
2020 Oskoui M, Kim DH, Mentis GZ, De Vivo DC. Transient hyperreflexia: An early diagnostic clue in later-onset spinal muscular atrophy. Neurology. Clinical Practice. 10: e66-e67. PMID 33520420 DOI: 10.1212/CPJ.0000000000000810  0.352
2020 Simon CM, Blanco-Redondo B, Buettner JM, Pagiazitis JG, Fletcher EV, Sime Longang JK, Mentis GZ. Chronic pharmacological increase of neuronal activity improves sensory-motor dysfunction in spinal muscular atrophy mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33219005 DOI: 10.1523/JNEUROSCI.2142-20.2020  0.537
2019 Simon CM, Van Alstyne M, Lotti F, Bianchetti E, Tisdale S, Watterson DM, Mentis GZ, Pellizzoni L. Stasimon Contributes to the Loss of Sensory Synapses and Motor Neuron Death in a Mouse Model of Spinal Muscular Atrophy. Cell Reports. 29: 3885-3901.e5. PMID 31851921 DOI: 10.1016/J.Celrep.2019.11.058  0.575
2019 Vukojicic A, Delestrée N, Fletcher EV, Pagiazitis JG, Sankaranarayanan S, Yednock TA, Barres BA, Mentis GZ. The Classical Complement Pathway Mediates Microglia-Dependent Remodeling of Spinal Motor Circuits during Development and in SMA. Cell Reports. 29: 3087-3100.e7. PMID 31801075 DOI: 10.1016/J.Celrep.2019.11.013  0.563
2018 Hoang PT, Chalif JI, Bikoff JB, Jessell TM, Mentis GZ, Wichterle H. Subtype Diversification and Synaptic Specificity of Stem Cell-Derived Spinal Interneurons. Neuron. 100: 135-149.e7. PMID 30308166 DOI: 10.1016/J.Neuron.2018.09.016  0.523
2018 Van Alstyne M, Simon CM, Sardi SP, Shihabuddin LS, Mentis GZ, Pellizzoni L. Dysregulation of Mdm2 and Mdm4 alternative splicing underlies motor neuron death in spinal muscular atrophy. Genes & Development. PMID 30012555 DOI: 10.1101/Gad.316059.118  0.557
2018 Cantor S, Zhang W, Delestrée N, Remédio L, Mentis GZ, Burden SJ. Preserving neuromuscular synapses in ALS by stimulating MuSK with a therapeutic agonist antibody. Elife. 7. PMID 29460776 DOI: 10.7554/Elife.34375  0.48
2017 Simon CM, Dai Y, Van Alstyne M, Koutsioumpa C, Pagiazitis JG, Chalif JI, Wang X, Rabinowitz JE, Henderson CE, Pellizzoni L, Mentis GZ. Converging Mechanisms of p53 Activation Drive Motor Neuron Degeneration in Spinal Muscular Atrophy. Cell Reports. 21: 3767-3780. PMID 29281826 DOI: 10.1016/J.Celrep.2017.12.003  0.576
2017 Fletcher EV, Simon CM, Pagiazitis JG, Chalif JI, Vukojicic A, Drobac E, Wang X, Mentis GZ. Reduced sensory synaptic excitation impairs motor neuron function via Kv2.1 in spinal muscular atrophy. Nature Neuroscience. PMID 28504671 DOI: 10.1038/Nn.4561  0.583
2016 Simon CM, Janas AM, Lotti F, Tapia JC, Pellizzoni L, Mentis GZ. A Stem Cell Model of the Motor Circuit Uncouples Motor Neuron Death from Hyperexcitability Induced by SMN Deficiency. Cell Reports. PMID 27452470 DOI: 10.1016/J.Celrep.2016.06.087  0.54
2016 Mende M, Fletcher EV, Belluardo JL, Pierce JP, Bommareddy PK, Weinrich JA, Kabir ZD, Schierberl KC, Pagiazitis JG, Mendelsohn AI, Francesconi A, Edwards RH, Milner TA, Rajadhyaksha AM, van Roessel PJ, ... Mentis GZ, et al. Sensory-Derived Glutamate Regulates Presynaptic Inhibitory Terminals in Mouse Spinal Cord. Neuron. PMID 27263971 DOI: 10.1016/J.Neuron.2016.05.008  0.511
2016 Remédio L, Gribble KD, Lee JK, Kim N, Hallock PT, Delestrée N, Mentis GZ, Froemke RC, Granato M, Burden SJ. Diverging roles for Lrp4 and Wnt signaling in neuromuscular synapse development during evolution. Genes & Development. 30: 1058-69. PMID 27151977 DOI: 10.1101/Gad.279745.116  0.378
2016 Bikoff JB, Gabitto MI, Rivard AF, Drobac E, Machado TA, Miri A, Brenner-Morton S, Famojure E, Diaz C, Alvarez FJ, Mentis GZ, Jessell TM. Spinal Inhibitory Interneuron Diversity Delineates Variant Motor Microcircuits. Cell. PMID 26949184 DOI: 10.1016/J.Cell.2016.01.027  0.529
2016 Sharma A, Lyashchenko AK, Lu L, Nasrabady SE, Elmaleh M, Mendelsohn M, Nemes A, Tapia JC, Mentis GZ, Shneider NA. ALS-associated mutant FUS induces selective motor neuron degeneration through toxic gain of function. Nature Communications. 7: 10465. PMID 26842965 DOI: 10.1038/Ncomms10465  0.454
2015 Mendelsohn AI, Simon CM, Abbott LF, Mentis GZ, Jessell TM. Activity Regulates the Incidence of Heteronymous Sensory-Motor Connections. Neuron. 87: 111-23. PMID 26094608 DOI: 10.1016/J.Neuron.2015.05.045  0.531
2015 de Nooij JC, Simon CM, Simon A, Doobar S, Steel KP, Banks RW, Mentis GZ, Bewick GS, Jessell TM. The PDZ-domain protein Whirlin facilitates mechanosensory signaling in mammalian proprioceptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 3073-84. PMID 25698744 DOI: 10.1523/Jneurosci.3699-14.2015  0.372
2013 Tisdale S, Lotti F, Saieva L, Van Meerbeke JP, Crawford TO, Sumner CJ, Mentis GZ, Pellizzoni L. SMN is essential for the biogenesis of U7 small nuclear ribonucleoprotein and 3'-end formation of histone mRNAs. Cell Reports. 5: 1187-95. PMID 24332368 DOI: 10.1016/J.Celrep.2013.11.012  0.356
2013 Fletcher EV, Mentis GZ. The Intrinsic Hyperexcitability of SMA Motor Neurons is a Result of Dysfunctional Spinal Circuitry Biophysical Journal. 104: 159a. DOI: 10.1016/J.Bpj.2012.11.896  0.538
2012 Lotti F, Imlach WL, Saieva L, Beck ES, Hao le T, Li DK, Jiao W, Mentis GZ, Beattie CE, McCabe BD, Pellizzoni L. An SMN-dependent U12 splicing event essential for motor circuit function. Cell. 151: 440-54. PMID 23063131 DOI: 10.1016/J.Cell.2012.09.012  0.546
2012 Mentis GZ. The Spinal and Peripheral Motor System Fundamental Neuroscience: Fourth Edition. 613-630. DOI: 10.1016/B978-0-12-385870-2.00028-7  0.574
2011 Mentis GZ, Blivis D, Liu W, Drobac E, Crowder ME, Kong L, Alvarez FJ, Sumner CJ, O'Donovan MJ. Early functional impairment of sensory-motor connectivity in a mouse model of spinal muscular atrophy. Neuron. 69: 453-67. PMID 21315257 DOI: 10.1016/J.Neuron.2010.12.032  0.698
2010 Siembab VC, Smith CA, Zagoraiou L, Berrocal MC, Mentis GZ, Alvarez FJ. Target selection of proprioceptive and motor axon synapses on neonatal V1-derived Ia inhibitory interneurons and Renshaw cells. The Journal of Comparative Neurology. 518: 4675-701. PMID 20963823 DOI: 10.1002/Cne.22441  0.511
2010 Mentis GZ, Alvarez FJ, Shneider NA, Siembab VC, O'Donovan MJ. Mechanisms regulating the specificity and strength of muscle afferent inputs in the spinal cord. Annals of the New York Academy of Sciences. 1198: 220-30. PMID 20536937 DOI: 10.1111/J.1749-6632.2010.05538.X  0.593
2010 Ziskind-Conhaim L, Mentis GZ, Wiesner EP, Titus DJ. Synaptic integration of rhythmogenic neurons in the locomotor circuitry: the case of Hb9 interneurons. Annals of the New York Academy of Sciences. 1198: 72-84. PMID 20536922 DOI: 10.1111/J.1749-6632.2010.05533.X  0.545
2010 O'Donovan MJ, Bonnot A, Mentis GZ, Chub N, Pujala A, Alvarez FJ. Mechanisms of excitation of spinal networks by stimulation of the ventral roots. Annals of the New York Academy of Sciences. 1198: 63-71. PMID 20536921 DOI: 10.1111/J.1749-6632.2010.05535.X  0.55
2010 Hinckley CA, Wiesner EP, Mentis GZ, Titus DJ, Ziskind-Conhaim L. Sensory modulation of locomotor-like membrane oscillations in Hb9-expressing interneurons. Journal of Neurophysiology. 103: 3407-23. PMID 20393069 DOI: 10.1152/Jn.00996.2009  0.553
2009 Fields DR, Shneider N, Mentis GZ, O'Donovan MJ. Imaging nervous system activity. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 2.3. PMID 19802815 DOI: 10.1002/0471142301.Ns0203S49  0.464
2009 Shneider NA, Mentis GZ, Schustak J, O'Donovan MJ. Functionally reduced sensorimotor connections form with normal specificity despite abnormal muscle spindle development: the role of spindle-derived neurotrophin 3. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 4719-35. PMID 19369542 DOI: 10.1523/Jneurosci.5790-08.2009  0.541
2008 O'Donovan MJ, Bonnot A, Mentis GZ, Arai Y, Chub N, Shneider NA, Wenner P. Imaging the spatiotemporal organization of neural activity in the developing spinal cord. Developmental Neurobiology. 68: 788-803. PMID 18383543 DOI: 10.1002/Dneu.20620  0.483
2007 Personius KE, Chang Q, Mentis GZ, O'Donovan MJ, Balice-Gordon RJ. Reduced gap junctional coupling leads to uncorrelated motor neuron firing and precocious neuromuscular synapse elimination. Proceedings of the National Academy of Sciences of the United States of America. 104: 11808-13. PMID 17609378 DOI: 10.1073/Pnas.0703357104  0.587
2007 Jean-Xavier C, Mentis GZ, O'Donovan MJ, Cattaert D, Vinay L. Dual personality of GABA/glycine-mediated depolarizations in immature spinal cord. Proceedings of the National Academy of Sciences of the United States of America. 104: 11477-82. PMID 17592145 DOI: 10.1073/Pnas.0704832104  0.492
2007 Mentis GZ, Díaz E, Moran LB, Navarrete R. Early alterations in the electrophysiological properties of rat spinal motoneurones following neonatal axotomy. The Journal of Physiology. 582: 1141-61. PMID 17510183 DOI: 10.1113/Jphysiol.2007.133488  0.442
2007 Arai Y, Mentis GZ, Wu JY, O'Donovan MJ. Ventrolateral origin of each cycle of rhythmic activity generated by the spinal cord of the chick embryo. Plos One. 2: e417. PMID 17479162 DOI: 10.1371/Journal.Pone.0000417  0.571
2007 Blivis D, Mentis GZ, O'donovan MJ, Lev-Tov A. Differential effects of opioids on sacrocaudal afferent pathways and central pattern generators in the neonatal rat spinal cord. Journal of Neurophysiology. 97: 2875-86. PMID 17287435 DOI: 10.1152/Jn.01313.2006  0.668
2006 Mentis GZ, Siembab VC, Zerda R, O'Donovan MJ, Alvarez FJ. Primary afferent synapses on developing and adult Renshaw cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 13297-310. PMID 17182780 DOI: 10.1523/Jneurosci.2945-06.2006  0.469
2006 Mentis GZ, Gravell M, Hamilton R, Shneider NA, O'Donovan MJ, Schubert M. Transduction of motor neurons and muscle fibers by intramuscular injection of HIV-1-based vectors pseudotyped with select rabies virus glycoproteins. Journal of Neuroscience Methods. 157: 208-17. PMID 16725205 DOI: 10.1016/J.Jneumeth.2006.04.011  0.513
2006 Chub N, Mentis GZ, O'donovan MJ. Chloride-sensitive MEQ fluorescence in chick embryo motoneurons following manipulations of chloride and during spontaneous network activity. Journal of Neurophysiology. 95: 323-30. PMID 16192339 DOI: 10.1152/Jn.00162.2005  0.398
2005 Mentis GZ, Alvarez FJ, Bonnot A, Richards DS, Gonzalez-Forero D, Zerda R, O'Donovan MJ. Noncholinergic excitatory actions of motoneurons in the neonatal mammalian spinal cord. Proceedings of the National Academy of Sciences of the United States of America. 102: 7344-9. PMID 15883359 DOI: 10.1073/Pnas.0502788102  0.529
2005 O'Donovan MJ, Bonnot A, Wenner P, Mentis GZ. Calcium imaging of network function in the developing spinal cord. Cell Calcium. 37: 443-50. PMID 15820392 DOI: 10.1016/J.Ceca.2005.01.012  0.543
2005 Bonnot A, Mentis GZ, Skoch J, O'Donovan MJ. Electroporation loading of calcium-sensitive dyes into the CNS. Journal of Neurophysiology. 93: 1793-808. PMID 15509647 DOI: 10.1152/Jn.00923.2004  0.5
2004 Benítez-Temiño B, Morcuende S, Mentis GZ, de la Cruz RR, Pastor AM. Expression of Trk receptors in the oculomotor system of the adult cat. The Journal of Comparative Neurology. 473: 538-52. PMID 15116389 DOI: 10.1002/Cne.20095  0.418
2003 Pastor AM, Mentis GZ, De La Cruz RR, Díaz E, Navarrete R. Increased electrotonic coupling in spinal motoneurons after transient botulinum neurotoxin paralysis in the neonatal rat. Journal of Neurophysiology. 89: 793-805. PMID 12574457 DOI: 10.1152/Jn.00498.2002  0.452
2002 Bonnot A, Whelan PJ, Mentis GZ, O'Donovan MJ. Locomotor-like activity generated by the neonatal mouse spinal cord. Brain Research. Brain Research Reviews. 40: 141-51. PMID 12589913 DOI: 10.1016/S0165-0173(02)00197-2  0.467
2002 Mentis GZ, Díaz E, Moran LB, Navarrete R. Increased incidence of gap junctional coupling between spinal motoneurones following transient blockade of NMDA receptors in neonatal rats. The Journal of Physiology. 544: 757-64. PMID 12411521 DOI: 10.1113/Jphysiol.2002.028159  0.386
2002 Bonnot A, Whelan PJ, Mentis GZ, O'Donovan MJ. Spatiotemporal pattern of motoneuron activation in the rostral lumbar and the sacral segments during locomotor-like activity in the neonatal mouse spinal cord. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: RC203. PMID 11826149 DOI: 10.1523/Jneurosci.22-03-J0001.2002  0.48
2001 Tapia JC, Mentis GZ, Navarrete R, Nualart F, Figueroa E, Sánchez A, Aguayo LG. Early expression of glycine and GABA(A) receptors in developing spinal cord neurons. Effects on neurite outgrowth. Neuroscience. 108: 493-506. PMID 11738262 DOI: 10.1016/S0306-4522(01)00348-7  0.466
2000 Tapia JC, Cárdenas AM, Nualart F, Mentis GZ, Navarrete R, Aguayo LG. Neurite outgrowth in developing mouse spinal cord neurons is modulated by glycine receptors. Neuroreport. 11: 3007-10. PMID 11006984 DOI: 10.1097/00001756-200009110-00036  0.53
2000 Virgo L, Dekkers J, Mentis GZ, Navarrete R, De Belleroche J. Changes in expression of NMDA receptor subunits in the rat lumbar spinal cord following neonatal nerve injury Neuropathology and Applied Neurobiology. 26: 258-272. PMID 10886684 DOI: 10.1046/J.1365-2990.2000.00244.X  0.409
1996 Hay C, Virgo L, Mentis G, Navarrete R, de Belleroche J. Changes in expression of NR-1 and c-jun mRNA in rat lumbar spinal cord after neonatal common peroneal nerve crush. Brain Research. 704: 145-50. PMID 8750977 DOI: 10.1016/0006-8993(95)01286-9  0.398
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