Petra Knaus - Publications

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98 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Trumpp M, Tan WH, Burdzinski W, Basler Y, Jatzlau J, Knaus P, Winkler C. Characterization of Fibrodysplasia Ossificans Progessiva relevant Acvr1/Acvr2 Activin receptors in medaka (Oryzias latipes). Plos One. 18: e0291379. PMID 37708126 DOI: 10.1371/journal.pone.0291379  0.391
2023 Quist-Løkken I, Andersson-Rusch C, Kastnes MH, Kolos JM, Jatzlau J, Hella H, Olsen OE, Sundan A, Knaus P, Hausch F, Holien T. FKBP12 is a major regulator of ALK2 activity in multiple myeloma cells. Cell Communication and Signaling : Ccs. 21: 25. PMID 36717825 DOI: 10.1186/s12964-022-01033-9  0.35
2023 Jatzlau J, Burdzinski W, Trumpp M, Obendorf L, Roßmann K, Ravn K, Hyvönen M, Bottanelli F, Broichhagen J, Knaus P. A versatile Halo- and SNAP-tagged BMP/TGFβ receptor library for quantification of cell surface ligand binding. Communications Biology. 6: 34. PMID 36635368 DOI: 10.1038/s42003-022-04388-4  0.329
2021 Reichenbach M, Mendez PL, da Silva Madaleno C, Ugorets V, Rikeit P, Boerno S, Jatzlau J, Knaus P. Differential Impact of Fluid Shear Stress and YAP/TAZ on BMP/TGF-β Induced Osteogenic Target Genes. Advanced Biology. 5: e2000051. PMID 36073990 DOI: 10.1002/adbi.202000051  0.311
2021 Mendez PL, Obendorf L, Knaus P. Visualization and Quantification of TGFβ/BMP/SMAD Signaling under Different Fluid Shear Stress Conditions using Proximity-Ligation-Assay. Journal of Visualized Experiments : Jove. PMID 34605801 DOI: 10.3791/62608  0.337
2021 Hildebrandt S, Kampfrath B, Fischer K, Hildebrand L, Haupt J, Stachelscheid H, Knaus P. ActivinA Induced SMAD1/5 Signaling in an iPSC Derived EC Model of Fibrodysplasia Ossificans Progressiva (FOP) Can Be Rescued by the Drug Candidate Saracatinib. Stem Cell Reviews and Reports. PMID 33410098 DOI: 10.1007/s12015-020-10103-9  0.336
2020 Hiepen C, Mendez PL, Knaus P. It Takes Two to Tango: Endothelial TGFβ/BMP Signaling Crosstalk with Mechanobiology. Cells. 9. PMID 32858894 DOI: 10.3390/cells9091965  0.435
2020 Fontana F, Haack T, Reichenbach M, Knaus P, Puceat M, Abdelilah-Seyfried S. Antagonistic Activities of Vegfr3/Flt4 and Notch1b Fine-tune Mechanosensitive Signaling during Zebrafish Cardiac Valvulogenesis. Cell Reports. 32: 107883. PMID 32668254 DOI: 10.1016/j.celrep.2020.107883  0.374
2020 da Silva Madaleno C, Jatzlau J, Knaus P. BMP signalling in a mechanical context - Implications for bone biology. Bone. 115416. PMID 32422297 DOI: 10.1016/j.bone.2020.115416  0.426
2020 Hiepen C, Jatzlau J, Knaus P. Biomechanical stress provides a second hit in the establishment of BMP/TGFβ-related vascular disorders. Cell Stress. 4: 44-47. PMID 32043077 DOI: 10.15698/cst2020.02.213  0.328
2019 Hiepen C, Jatzlau J, Hildebrandt S, Kampfrath B, Goktas M, Murgai A, Cuellar Camacho JL, Haag R, Ruppert C, Sengle G, Cavalcanti-Adam EA, Blank KG, Knaus P. BMPR2 acts as a gatekeeper to protect endothelial cells from increased TGFβ responses and altered cell mechanics. Plos Biology. 17: e3000557. PMID 31826007 DOI: 10.1371/Journal.Pbio.3000557  0.492
2019 Brunner P, Hastar N, Kaehler C, Burdzinski W, Jatzlau J, Knaus P. AMOT130 drives BMP-SMAD signaling at the apical membrane in polarized cells. Molecular Biology of the Cell. mbcE19030179. PMID 31800378 DOI: 10.1091/mbc.E19-03-0179  0.446
2019 Salah E, Chatterjee D, Beltrami A, Tumber A, Preuss F, Canning P, Chaikuad A, Knaus P, Knapp S, Bullock AN, Mathea S. Lessons from LIMK1 enzymology and their impact on inhibitor design. The Biochemical Journal. PMID 31652302 DOI: 10.1042/BCJ20190517  0.3
2019 Differ C, Klatte-Schulz F, Bormann N, Minkwitz S, Knaus P, Wildemann B. Is NO the Answer? The Nitric Oxide Pathway Can Support Bone Morphogenetic Protein 2 Mediated Signaling. Cells. 8. PMID 31635347 DOI: 10.3390/cells8101273  0.479
2019 Schreivogel S, Kuchibhotla V, Knaus P, Duda GN, Petersen A. Load-induced osteogenic differentiation of mesenchymal stromal cells is caused by mechano-regulated autocrine signaling. Journal of Tissue Engineering and Regenerative Medicine. PMID 31359634 DOI: 10.1002/term.2948  0.425
2018 Puts R, Rikeit P, Ruschke K, Knaus P, Schreivogel S, Raum K. Functional regulation of YAP mechanosensitive transcriptional coactivator by Focused Low-Intensity Pulsed Ultrasound (FLIPUS) enhances proliferation of murine mesenchymal precursors. Plos One. 13: e0206041. PMID 30365513 DOI: 10.1371/journal.pone.0206041  0.334
2018 Chatzifrangkeskou M, Yadin D, Marais T, Chardonnet S, Cohen-Tannoudji M, Mougenot N, Schmitt A, Crasto S, Di Pasquale E, Macquart C, Tanguy Y, Jebeniani I, Pucéat M, Morales Rodriguez B, Goldmann WH, ... ... Knaus P, et al. Cofilin-1 phosphorylation catalyzed by ERK1/2 alters cardiac actin dynamics in dilated cardiomyopathy caused by lamin A/C gene mutation. Human Molecular Genetics. PMID 29878125 DOI: 10.1093/Hmg/Ddy215  0.342
2018 Olsen OE, Sankar M, Elsaadi S, Hella H, Buene G, Darvekar SR, Misund K, Katagiri T, Knaus P, Holien T. BMPR2 inhibits activin- and BMP-signaling via wild type ALK2. Journal of Cell Science. PMID 29739878 DOI: 10.1242/jcs.213512  0.498
2018 Chan WL, Steiner M, Witkos T, Egerer J, Busse B, Mizumoto S, Pestka JM, Zhang H, Hausser I, Khayal LA, Ott CE, Kolanczyk M, Willie B, Schinke T, Paganini C, ... ... Knaus P, et al. Impaired proteoglycan glycosylation, elevated TGF-β signaling, and abnormal osteoblast differentiation as the basis for bone fragility in a mouse model for gerodermia osteodysplastica. Plos Genetics. 14: e1007242. PMID 29561836 DOI: 10.1371/Journal.Pgen.1007242  0.401
2018 Strasen J, Sarma U, Jentsch M, Bohn S, Sheng C, Horbelt D, Knaus P, Legewie S, Loewer A. Cell-specific responses to the cytokine TGFβ are determined by variability in protein levels. Molecular Systems Biology. 14: e7733. PMID 29371237 DOI: 10.15252/Msb.20177733  0.425
2017 Bagarova J, Vonner AJ, Armstrong KA, Börgermann J, Lai CSC, Deng DY, Beppu H, Alfano I, Filippakopoulos P, Morrell NW, Bullock AN, Knaus P, Mishina Y, Yu PB. Correction for Bagarova et al., "Constitutively Active ALK2 Receptor Mutants Require Type II Receptor Cooperation". Molecular and Cellular Biology. 37. PMID 28899999 DOI: 10.1128/Mcb.00284-17  0.333
2017 Dörpholz G, Murgai A, Jatzlau J, Horbelt D, Belverdi MP, Heroven C, Schreiber I, Wendel G, Ruschke K, Stricker S, Knaus P. IRS4, a novel modulator of BMP/Smad and Akt signalling during early muscle differentiation. Scientific Reports. 7: 8778. PMID 28821740 DOI: 10.1038/S41598-017-08676-6  0.491
2017 Benn A, Hiepen C, Osterland M, Schütte C, Zwijsen A, Knaus P. Role of bone morphogenetic proteins in sprouting angiogenesis: differential BMP receptor-dependent signaling pathways balance stalk vs. tip cell competence. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28733457 DOI: 10.1096/fj.201700193RR  0.52
2016 Klatte-Schulz F, Giese G, Differ C, Minkwitz S, Ruschke K, Puts R, Knaus P, Wildemann B. An investigation of BMP-7 mediated alterations to BMP signalling components in human tenocyte-like cells. Scientific Reports. 6: 29703. PMID 27406972 DOI: 10.1038/srep29703  0.494
2016 Paarmann P, Dörpholz G, Fiebig J, Amsalem AR, Ehrlich M, Henis YI, Müller T, Knaus P. Dynamin-dependent endocytosis of Bone Morphogenetic Protein2 (BMP2) and its receptors is dispensable for the initiation of Smad signaling. The International Journal of Biochemistry & Cell Biology. PMID 27113717 DOI: 10.1016/j.biocel.2016.04.010  0.531
2016 Fischer M, Rikeit P, Knaus P, Coirault C. YAP-Mediated Mechanotransduction in Skeletal Muscle. Frontiers in Physiology. 7: 41. PMID 26909043 DOI: 10.3389/fphys.2016.00041  0.349
2016 Hiepen C, Yadin D, Rikeit P, Dörpholz G, Knaus P. Actions from head to toe: An update on Bone/Body Morphogenetic Proteins in health and disease. Cytokine & Growth Factor Reviews. PMID 26803465 DOI: 10.1016/j.cytogfr.2015.12.006  0.409
2016 Amsalem AR, Marom B, Shapira KE, Hirschhorn T, Preisler L, Paarmann P, Knaus P, Henis YI, Ehrlich M. Differential regulation of translation and endocytosis of alternatively spliced forms of the type II bone morphogenetic protein (BMP) receptor. Molecular Biology of the Cell. PMID 26739752 DOI: 10.1091/mbc.E15-08-0547  0.472
2016 Dörpholz G, Weigell P, Knaus P. BMP-Signaltransduktion – begleitet von control freaks und gate keepers Biospektrum. 22: 686-690. DOI: 10.1007/S12268-016-0743-7  0.438
2015 García de Vinuesa A, Abdelilah-Seyfried S, Knaus P, Zwijsen A, Bailly S. BMP signaling in vascular biology and dysfunction. Cytokine & Growth Factor Reviews. PMID 26823333 DOI: 10.1016/j.cytogfr.2015.12.005  0.388
2015 Yadin D, Knaus P, Mueller TD. Structural insights into BMP receptors: Specificity, activation and inhibition. Cytokine & Growth Factor Reviews. PMID 26690041 DOI: 10.1016/j.cytogfr.2015.11.005  0.505
2015 Benn A, Bredow C, Casanova I, Vukičević S, Knaus P. VE-Cadherin facilitates BMP-induced endothelial cell permeability and signaling. Journal of Cell Science. PMID 26598555 DOI: 10.1242/jcs.179960  0.445
2015 Sánchez-Duffhues G, Hiepen C, Knaus P, Ten Dijke P. Bone morphogenetic protein signaling in bone homeostasis. Bone. 80: 43-59. PMID 26051467 DOI: 10.1016/j.bone.2015.05.025  0.444
2015 Schwab EH, Pohl TL, Haraszti T, Schwaerzer GK, Hiepen C, Spatz JP, Knaus P, Cavalcanti-Adam EA. Nanoscale control of surface immobilized BMP-2: toward a quantitative assessment of BMP-mediated signaling events. Nano Letters. 15: 1526-34. PMID 25668064 DOI: 10.1021/acs.nanolett.5b00315  0.398
2015 Grünhagen J, Bhushan R, Degenkolbe E, Jäger M, Knaus P, Mundlos S, Robinson PN, Ott CE. MiR-497∼195 cluster microRNAs regulate osteoblast differentiation by targeting BMP signaling. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 30: 796-808. PMID 25407900 DOI: 10.1002/Jbmr.2412  0.319
2015 Horbelt D, Boergermann JH, Chaikuad A, Alfano I, Williams E, Lukonin I, Timmel T, Bullock AN, Knaus P. Small molecules dorsomorphin and LDN-193189 inhibit myostatin/GDF8 signaling and promote functional myoblast differentiation. The Journal of Biological Chemistry. 290: 3390-404. PMID 25368322 DOI: 10.1074/jbc.M114.604397  0.457
2015 Dörpholz G, Ruschke K, Horbelt D, Wendel G, Belverdi MP, Knaus P. Insulin receptor substrate 4 (IRS4) affects myogenic differentiation by modulating BMP signalling Diabetologie Und Stoffwechsel. 10: 77. DOI: 10.1055/S-0035-1549583  0.391
2014 Hiepen C, Benn A, Denkis A, Lukonin I, Weise C, Boergermann JH, Knaus P. BMP2-induced chemotaxis requires PI3K p55γ/p110α-dependent phosphatidylinositol (3,4,5)-triphosphate production and LL5β recruitment at the cytocortex. Bmc Biology. 12: 43. PMID 24885555 DOI: 10.1186/1741-7007-12-43  0.437
2014 Kopf J, Paarmann P, Hiepen C, Horbelt D, Knaus P. BMP growth factor signaling in a biomechanical context. Biofactors (Oxford, England). 40: 171-87. PMID 24123658 DOI: 10.1002/biof.1137  0.457
2014 Klatte-Schulz F, Giese G, Ruschke K, Puts R, Knaus P, Wildemann B. 51 Insights Into Bmp-7 Signalling Of Rotator Cuff Tenocytes British Journal of Sports Medicine. 48. DOI: 10.1136/Bjsports-2014-094114.51  0.397
2013 Lichtner B, Knaus P, Lehrach H, Adjaye J. BMP10 as a potent inducer of trophoblast differentiation in human embryonic and induced pluripotent stem cells. Biomaterials. 34: 9789-802. PMID 24070570 DOI: 10.1016/J.Biomaterials.2013.08.084  0.406
2013 Tykwinska K, Lauster R, Knaus P, Rosowski M. Growth and differentiation factor 3 induces expression of genes related to differentiation in a model of cancer stem cells and protects them from retinoic acid-induced apoptosis. Plos One. 8: e70612. PMID 23950971 DOI: 10.1371/journal.pone.0070612  0.316
2013 Bagarova J, Vonner AJ, Armstrong KA, Börgermann J, Lai CS, Deng DY, Beppu H, Alfano I, Filippakopoulos P, Morrell NW, Bullock AN, Knaus P, Mishina Y, Yu PB. Constitutively active ALK2 receptor mutants require type II receptor cooperation. Molecular and Cellular Biology. 33: 2413-24. PMID 23572558 DOI: 10.1128/Mcb.01595-12  0.502
2013 Guo G, Muñoz-García B, Ott CE, Grünhagen J, Mousa SA, Pletschacher A, von Kodolitsch Y, Knaus P, Robinson PN. Antagonism of GxxPG fragments ameliorates manifestations of aortic disease in Marfan syndrome mice. Human Molecular Genetics. 22: 433-43. PMID 23100322 DOI: 10.1093/hmg/dds439  0.322
2013 Henis YI, Marom B, Shapira KE, Knaus P, Ehrlich M. TGF-Beta and Bmp Receptors: Distinct Modes of Oligomeric Interactions and Implications for Signaling Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.3393  0.48
2012 Chaikuad A, Alfano I, Kerr G, Sanvitale CE, Boergermann JH, Triffitt JT, von Delft F, Knapp S, Knaus P, Bullock AN. Structure of the bone morphogenetic protein receptor ALK2 and implications for fibrodysplasia ossificans progressiva. The Journal of Biological Chemistry. 287: 36990-8. PMID 22977237 DOI: 10.1074/jbc.M112.365932  0.468
2012 Guzman A, Zelman-Femiak M, Boergermann JH, Paschkowsky S, Kreuzaler PA, Fratzl P, Harms GS, Knaus P. SMAD versus non-SMAD signaling is determined by lateral mobility of bone morphogenetic protein (BMP) receptors. The Journal of Biological Chemistry. 287: 39492-504. PMID 22961979 DOI: 10.1074/jbc.M112.387639  0.51
2012 Kopf J, Petersen A, Duda GN, Knaus P. BMP2 and mechanical loading cooperatively regulate immediate early signalling events in the BMP pathway. Bmc Biology. 10: 37. PMID 22540193 DOI: 10.1186/1741-7007-10-37  0.461
2012 Ruschke K, Hiepen C, Becker J, Knaus P. BMPs are mediators in tissue crosstalk of the regenerating musculoskeletal system. Cell and Tissue Research. 347: 521-44. PMID 22327483 DOI: 10.1007/s00441-011-1283-6  0.367
2012 Ehrlich M, Gutman O, Knaus P, Henis YI. Oligomeric interactions of TGF-β and BMP receptors. Febs Letters. 586: 1885-96. PMID 22293501 DOI: 10.1016/j.febslet.2012.01.040  0.502
2012 Horbelt D, Denkis A, Knaus P. A portrait of Transforming Growth Factor β superfamily signalling: Background matters. The International Journal of Biochemistry & Cell Biology. 44: 469-74. PMID 22226817 DOI: 10.1016/j.biocel.2011.12.013  0.497
2012 Pohl TL, Boergermann JH, Schwaerzer GK, Knaus P, Cavalcanti-Adam EA. Surface immobilization of bone morphogenetic protein 2 via a self-assembled monolayer formation induces cell differentiation. Acta Biomaterialia. 8: 772-80. PMID 22040684 DOI: 10.1016/j.actbio.2011.10.019  0.418
2012 Schwaerzer GK, Hiepen C, Schrewe H, Nickel J, Ploeger F, Sebald W, Mueller T, Knaus P. New insights into the molecular mechanism of multiple synostoses syndrome (SYNS): mutation within the GDF5 knuckle epitope causes noggin-resistance. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 27: 429-42. PMID 21976273 DOI: 10.1002/jbmr.532  0.421
2012 Poorgholi Belverdi M, Krause C, Guzman A, Knaus P. Comprehensive analysis of TGF-β and BMP receptor interactomes. European Journal of Cell Biology. 91: 287-93. PMID 21715044 DOI: 10.1016/j.ejcb.2011.05.004  0.466
2011 Heining E, Bhushan R, Paarmann P, Henis YI, Knaus P. Spatial segregation of BMP/Smad signaling affects osteoblast differentiation in C2C12 cells. Plos One. 6: e25163. PMID 21998639 DOI: 10.1371/journal.pone.0025163  0.48
2011 Ehrlich M, Horbelt D, Marom B, Knaus P, Henis YI. Homomeric and heteromeric complexes among TGF-β and BMP receptors and their roles in signaling. Cellular Signalling. 23: 1424-32. PMID 21515362 DOI: 10.1016/j.cellsig.2011.04.004  0.5
2011 Marom B, Heining E, Knaus P, Henis YI. Formation of stable homomeric and transient heteromeric bone morphogenetic protein (BMP) receptor complexes regulates Smad protein signaling. The Journal of Biological Chemistry. 286: 19287-96. PMID 21471205 DOI: 10.1074/jbc.M110.210377  0.509
2011 Krause C, Guzman A, Knaus P. Noggin. The International Journal of Biochemistry & Cell Biology. 43: 478-81. PMID 21256973 DOI: 10.1016/j.biocel.2011.01.007  0.327
2010 Horbelt D, Guo G, Robinson PN, Knaus P. Quantitative analysis of TGFBR2 mutations in Marfan-syndrome-related disorders suggests a correlation between phenotypic severity and Smad signaling activity. Journal of Cell Science. 123: 4340-50. PMID 21098638 DOI: 10.1242/jcs.074773  0.372
2010 Boergermann JH, Kopf J, Yu PB, Knaus P. Dorsomorphin and LDN-193189 inhibit BMP-mediated Smad, p38 and Akt signalling in C2C12 cells. The International Journal of Biochemistry & Cell Biology. 42: 1802-7. PMID 20691279 DOI: 10.1016/j.biocel.2010.07.018  0.523
2010 Wagner DO, Sieber C, Bhushan R, Börgermann JH, Graf D, Knaus P. BMPs: from bone to body morphogenetic proteins. Science Signaling. 3: mr1. PMID 20124549 DOI: 10.1126/scisignal.3107mr1  0.488
2009 Sieber C, Kopf J, Hiepen C, Knaus P. Recent advances in BMP receptor signaling. Cytokine & Growth Factor Reviews. 20: 343-55. PMID 19897402 DOI: 10.1016/j.cytogfr.2009.10.007  0.547
2009 Hauburger A, von Einem S, Schwaerzer GK, Buttstedt A, Zebisch M, Schräml M, Hortschansky P, Knaus P, Schwarz E. The pro-form of BMP-2 interferes with BMP-2 signalling by competing with BMP-2 for IA receptor binding. The Febs Journal. 276: 6386-98. PMID 19804412 DOI: 10.1111/j.1742-4658.2009.07361.x  0.407
2009 Schwappacher R, Weiske J, Heining E, Ezerski V, Marom B, Henis YI, Huber O, Knaus P. Novel crosstalk to BMP signalling: cGMP-dependent kinase I modulates BMP receptor and Smad activity. The Embo Journal. 28: 1537-50. PMID 19424179 DOI: 10.1038/emboj.2009.103  0.521
2009 Bengtsson L, Schwappacher R, Roth M, Boergermann JH, Hassel S, Knaus P. PP2A regulates BMP signalling by interacting with BMP receptor complexes and by dephosphorylating both the C-terminus and the linker region of Smad1. Journal of Cell Science. 122: 1248-57. PMID 19339557 DOI: 10.1242/jcs.039552  0.527
2009 Sammar M, Sieber C, Knaus P. Biochemical and functional characterization of the Ror2/BRIb receptor complex. Biochemical and Biophysical Research Communications. 381: 1-6. PMID 19135982 DOI: 10.1016/j.bbrc.2008.12.162  0.433
2009 Heining E, Schwappacher R, Horbelt D, Huber O, Knaus P. Crosstalk of cyclic GMP dependent kinase I and BMP signaling Bmc Pharmacology. 9: 23. DOI: 10.1186/1471-2210-9-S1-P23  0.557
2008 Zavala-Góngora R, Derrer B, Gelmedin V, Knaus P, Brehm K. Molecular characterisation of a second structurally unusual AR-Smad without an MH1 domain and a Smad4 orthologue from Echinococcus multilocularis. International Journal For Parasitology. 38: 161-76. PMID 17845804 DOI: 10.1016/j.ijpara.2007.07.008  0.431
2007 Morty RE, Nejman B, Kwapiszewska G, Hecker M, Zakrzewicz A, Kouri FM, Peters DM, Dumitrascu R, Seeger W, Knaus P, Schermuly RT, Eickelberg O. Dysregulated bone morphogenetic protein signaling in monocrotaline-induced pulmonary arterial hypertension. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 1072-8. PMID 17347486 DOI: 10.1161/ATVBAHA.107.141200  0.47
2007 Schwappacher R, Weiske J, Ezerski V, Hassel S, Huber O, Knaus P. Cyclic GMP-dependent kinase I promotes BMP signaling Bmc Pharmacology. 7: 54. DOI: 10.1186/1471-2210-7-S1-P54  0.393
2006 Lehmann K, Seemann P, Boergermann J, Morin G, Reif S, Knaus P, Mundlos S. A novel R486Q mutation in BMPR1B resulting in either a brachydactyly type C/symphalangism-like phenotype or brachydactyly type A2. European Journal of Human Genetics : Ejhg. 14: 1248-54. PMID 16957682 DOI: 10.1038/Sj.Ejhg.5201708  0.311
2006 Hartung A, Bitton-Worms K, Rechtman MM, Wenzel V, Boergermann JH, Hassel S, Henis YI, Knaus P. Different routes of bone morphogenic protein (BMP) receptor endocytosis influence BMP signaling. Molecular and Cellular Biology. 26: 7791-805. PMID 16923969 DOI: 10.1128/MCB.00022-06  0.521
2006 Sieber C, Plöger F, Schwappacher R, Bechtold R, Hanke M, Kawai S, Muraki Y, Katsuura M, Kimura M, Rechtman MM, Henis YI, Pohl J, Knaus P. Monomeric and dimeric GDF-5 show equal type I receptor binding and oligomerization capability and have the same biological activity. Biological Chemistry. 387: 451-60. PMID 16606344 DOI: 10.1515/BC.2006.060  0.419
2006 Meyer-Ter-Vehn T, Gebhardt S, Sebald W, Buttmann M, Grehn F, Schlunck G, Knaus P. p38 inhibitors prevent TGF-beta-induced myofibroblast transdifferentiation in human tenon fibroblasts. Investigative Ophthalmology & Visual Science. 47: 1500-9. PMID 16565385 DOI: 10.1167/iovs.05-0361  0.33
2006 Klein J, Ju W, Heyer J, Wittek B, Haneke T, Knaus P, Kucherlapati R, Böttinger EP, Nitschke L, Kneitz B. B cell-specific deficiency for Smad2 in vivo leads to defects in TGF-beta-directed IgA switching and changes in B cell fate. Journal of Immunology (Baltimore, Md. : 1950). 176: 2389-96. PMID 16455997 DOI: 10.4049/Jimmunol.176.4.2389  0.358
2006 Zavala-Góngora R, Kroner A, Bernthaler P, Knaus P, Brehm K. A member of the transforming growth factor-beta receptor family from Echinococcus multilocularis is activated by human bone morphogenetic protein 2. Molecular and Biochemical Parasitology. 146: 265-71. PMID 16434111 DOI: 10.1016/j.molbiopara.2005.12.011  0.379
2006 Hassel S, Yakymovych M, Hellman U, Rönnstrand L, Knaus P, Souchelnytskyi S. Interaction and functional cooperation between the serine/threonine kinase bone morphogenetic protein type II receptor with the tyrosine kinase stem cell factor receptor. Journal of Cellular Physiology. 206: 457-67. PMID 16155937 DOI: 10.1002/jcp.20480  0.412
2006 Hartung A, Sieber C, Knaus P. Yin and Yang in BMP signaling: Impact on the pathology of diseases and potential for tissue regeneration Signal Transduction. 6: 314-328. DOI: 10.1002/sita.200600098  0.505
2005 Seemann P, Schwappacher R, Kjaer KW, Krakow D, Lehmann K, Dawson K, Stricker S, Pohl J, Plöger F, Staub E, Nickel J, Sebald W, Knaus P, Mundlos S. Activating and deactivating mutations in the receptor interaction site of GDF5 cause symphalangism or brachydactyly type A2. The Journal of Clinical Investigation. 115: 2373-81. PMID 16127465 DOI: 10.1172/Jci25118  0.395
2005 Nohe A, Keating E, Underhill TM, Knaus P, Petersen NO. Dynamics and interaction of caveolin-1 isoforms with BMP-receptors. Journal of Cell Science. 118: 643-50. PMID 15657086 DOI: 10.1242/Jcs.01402  0.435
2004 Sammar M, Stricker S, Schwabe GC, Sieber C, Hartung A, Hanke M, Oishi I, Pohl J, Minami Y, Sebald W, Mundlos S, Knaus P. Modulation of GDF5/BRI-b signalling through interaction with the tyrosine kinase receptor Ror2. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 9: 1227-38. PMID 15569154 DOI: 10.1111/J.1365-2443.2004.00799.X  0.451
2004 Hassel S, Eichner A, Yakymovych M, Hellman U, Knaus P, Souchelnytskyi S. Proteins associated with type II bone morphogenetic protein receptor (BMPR-II) and identified by two-dimensional gel electrophoresis and mass spectrometry. Proteomics. 4: 1346-58. PMID 15188402 DOI: 10.1002/pmic.200300770  0.423
2004 Schiemann WP, Rotzer D, Pfeifer WM, Levi E, Rai KR, Knaus P, Kadin ME. Transforming growth factor-beta (TGF-beta)-resistant B cells from chronic lymphocytic leukemia patients contain recurrent mutations in the signal sequence of the type I TGF-beta receptor. Cancer Detection and Prevention. 28: 57-64. PMID 15041079 DOI: 10.1016/J.Cdp.2003.11.001  0.317
2004 Lutz M, Krieglstein K, Schmitt S, ten Dijke P, Sebald W, Wizenmann A, Knaus P. Nerve growth factor mediates activation of the Smad pathway in PC12 cells. European Journal of Biochemistry / Febs. 271: 920-31. PMID 15009204 DOI: 10.1111/j.1432-1033.2004.03994.x  0.424
2004 Nohe A, Keating E, Knaus P, Petersen NO. Signal transduction of bone morphogenetic protein receptors. Cellular Signalling. 16: 291-9. PMID 14687659 DOI: 10.1016/J.Cellsig.2003.08.011  0.507
2003 Zavala-Góngora R, Kroner A, Wittek B, Knaus P, Brehm K. Identification and characterisation of two distinct Smad proteins from the fox-tapeworm Echinococcus multilocularis. International Journal For Parasitology. 33: 1665-77. PMID 14636682 DOI: 10.1016/S0020-7519(03)00208-X  0.444
2003 Lehmann K, Seemann P, Stricker S, Sammar M, Meyer B, Süring K, Majewski F, Tinschert S, Grzeschik KH, Müller D, Knaus P, Nürnberg P, Mundlos S. Mutations in bone morphogenetic protein receptor 1B cause brachydactyly type A2. Proceedings of the National Academy of Sciences of the United States of America. 100: 12277-82. PMID 14523231 DOI: 10.1073/Pnas.2133476100  0.358
2003 Hassel S, Schmitt S, Hartung A, Roth M, Nohe A, Petersen N, Ehrlich M, Henis YI, Sebald W, Knaus P. Initiation of Smad-dependent and Smad-independent signaling via distinct BMP-receptor complexes. The Journal of Bone and Joint Surgery. American Volume. 85: 44-51. PMID 12925609 DOI: 10.2106/00004623-200300003-00009  0.519
2003 Nohe A, Keating E, Underhill TM, Knaus P, Petersen NO. Effect of the distribution and clustering of the type I A BMP receptor (ALK3) with the type II BMP receptor on the activation of signalling pathways. Journal of Cell Science. 116: 3277-84. PMID 12829744 DOI: 10.1242/Jcs.00519  0.515
2003 Pohl F, Hassel S, Nohe A, Flentje M, Knaus P, Sebald W, Koelbl O. Radiation-induced suppression of the Bmp2 signal transduction pathway in the pluripotent mesenchymal cell line C2C12: an in vitro model for prevention of heterotopic ossification by radiotherapy. Radiation Research. 159: 345-50. PMID 12600237 DOI: 10.1667/0033-7587(2003)159[0345:Risotb]2.0.Co;2  0.372
2003 Gekle M, Knaus P, Nielsen R, Mildenberger S, Freudinger R, Wohlfarth V, Sauvant C, Christensen EI. Transforming growth factor‐β1 reduces megalin‐ and cubilin‐mediated endocytosis of albumin in proximal‐tubule‐derived opossum kidney cells The Journal of Physiology. 552: 471-481. DOI: 10.1111/J.1469-7793.2003.00471.X  0.305
2002 Lutz M, Knaus P. Integration of the TGF-beta pathway into the cellular signalling network. Cellular Signalling. 14: 977-88. PMID 12359303 DOI: 10.1016/S0898-6568(02)00058-X  0.494
2002 Feldmann K, Sebald W, Knaus P. Resistance to TGF-beta1-mediated growth inhibition correlates with sustained Smad2 phosphorylation in primary murine splenocytes. European Journal of Immunology. 32: 1393-402. PMID 11981827 DOI: 10.1002/1521-4141(200205)32:5<1393::AID-IMMU1393>3.0.CO;2-M  0.338
2002 Nohe A, Hassel S, Ehrlich M, Neubauer F, Sebald W, Henis YI, Knaus P. The mode of bone morphogenetic protein (BMP) receptor oligomerization determines different BMP-2 signaling pathways. The Journal of Biological Chemistry. 277: 5330-8. PMID 11714695 DOI: 10.1074/Jbc.M102750200  0.754
2001 Knaus P, Sebald W. Cooperativity of binding epitopes and receptor chains in the BMP/TGFbeta superfamily. Biological Chemistry. 382: 1189-95. PMID 11592400 DOI: 10.1515/BC.2001.149  0.486
2001 Rotzer D, Roth M, Lutz M, Lindemann D, Sebald W, Knaus P. Type III TGF-beta receptor-independent signalling of TGF-beta2 via TbetaRII-B, an alternatively spliced TGF-beta type II receptor. The Embo Journal. 20: 480-90. PMID 11157754 DOI: 10.1093/emboj/20.3.480  0.514
2000 Gilboa L, Nohe A, Geissendörfer T, Sebald W, Henis YI, Knaus P. Bone morphogenetic protein receptor complexes on the surface of live cells: a new oligomerization mode for serine/threonine kinase receptors. Molecular Biology of the Cell. 11: 1023-35. PMID 10712517 DOI: 10.1091/Mbc.11.3.1023  0.462
1987 Schmitt B, Knaus P, Becker CM, Betz H. The Mr 93,000 polypeptide of the postsynaptic glycine receptor complex is a peripheral membrane protein. Biochemistry. 26: 805-11. PMID 3032237 DOI: 10.1021/Bi00377A022  0.353
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