| Year |
Citation |
Score |
| 2023 |
Schilling KM, Jorwal P, Ubilla-Rodriguez NC, Assafa TE, Gatdula JRP, Vultaggio JS, Harris DA, Millhauser GL. N-Glycosylation is a Potent Regulator of Prion Protein Neurotoxicity. The Journal of Biological Chemistry. 105101. PMID 37507020 DOI: 10.1016/j.jbc.2023.105101 |
0.39 |
|
| 2022 |
Mercer RCC, Harris DA. Mechanisms of prion-induced toxicity. Cell and Tissue Research. PMID 36070155 DOI: 10.1007/s00441-022-03683-0 |
0.337 |
|
| 2020 |
Kim SY, Zhang F, Harris DA, Linhardt RJ. Structural Features of Heparin and Its Interactions With Cellular Prion Protein Measured by Surface Plasmon Resonance. Frontiers in Molecular Biosciences. 7: 594497. PMID 33324681 DOI: 10.3389/fmolb.2020.594497 |
0.333 |
|
| 2020 |
Schilling KM, Tao L, Wu B, Kiblen JTM, Ubilla-Rodriguez NC, Pushie MJ, Britt RD, Roseman GP, Harris DA, Millhauser GL. Both N-Terminal and C-Terminal Histidine Residues of the Prion Protein are Essential for Copper Coordination and Neuroprotective Self-Regulation. Journal of Molecular Biology. PMID 32473880 DOI: 10.1016/J.Jmb.2020.05.020 |
0.433 |
|
| 2020 |
Roseman GP, Wu B, Wadolkowski MA, Harris DA, Millhauser GL. Intrinsic toxicity of the cellular prion protein is regulated by its conserved central region. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32385908 DOI: 10.1096/Fj.201902749Rr |
0.397 |
|
| 2019 |
Corbett GT, Wang Z, Hong W, Colom-Cadena M, Rose J, Liao M, Asfaw A, Hall TC, Ding L, DeSousa A, Frosch MP, Collinge J, Harris DA, Perkinton MS, Spires-Jones TL, et al. PrP is a central player in toxicity mediated by soluble aggregates of neurodegeneration-causing proteins. Acta Neuropathologica. PMID 31853635 DOI: 10.1007/S00401-019-02114-9 |
0.452 |
|
| 2019 |
McDonald AJ, Leon DR, Markham KA, Wu B, Heckendorf CF, Schilling K, Showalter HD, Andrews PC, McComb ME, Pushie MJ, Costello CE, Millhauser GL, Harris DA. Altered Domain Structure of the Prion Protein Caused by Cu Binding and Functionally Relevant Mutations: Analysis by Cross-Linking, MS/MS, and NMR. Structure (London, England : 1993). PMID 30956132 DOI: 10.1016/J.Str.2019.03.008 |
0.418 |
|
| 2019 |
Mercer RC, Harris DA. Identification of anti-prion drugs and targets using toxicity-based assays. Current Opinion in Pharmacology. 44: 20-27. PMID 30684854 DOI: 10.1016/j.coph.2018.12.005 |
0.443 |
|
| 2019 |
Amin L, Harris DA. P4-507: INHIBITORY EFFECT OF RECEPTOR PROTEINS ON Aβ AGGREGATION PROCESS Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.08.053 |
0.319 |
|
| 2018 |
Mengel D, Hong W, Corbett GT, Liu W, DeSousa A, Solforosi L, Fang C, Frosch MP, Collinge J, Harris D, Walsh DM. PrP-grafted antibodies bind certain amyloid β-protein aggregates, but do not prevent toxicity. Brain Research. PMID 30593771 DOI: 10.1016/J.Brainres.2018.12.038 |
0.405 |
|
| 2018 |
Le NTT, Wu B, Harris DA. MINI-SYMPOSIUM: Recent advances in the molecular pathology of prion diseases. Brain Pathology (Zurich, Switzerland). PMID 30588688 DOI: 10.1111/bpa.12694 |
0.48 |
|
| 2018 |
Fang C, Wu B, Le NTT, Imberdis T, Mercer RCC, Harris DA. Prions activate a p38 MAPK synaptotoxic signaling pathway. Plos Pathogens. 14: e1007283. PMID 30235355 DOI: 10.1371/journal.ppat.1007283 |
0.38 |
|
| 2018 |
Roseman GP, McDonald AJ, Wu B, Harris DA, Millhauser GL. Proteolytically Resistant Cellular Prion Protein Construct Retains Metal Driven CIS-Interaction while Generating Toxicity in Cells Biophysical Journal. 114: 568a. DOI: 10.1016/J.Bpj.2017.11.3107 |
0.338 |
|
| 2017 |
McDonald AJ, Wu B, Harris DA. An Inter-Domain Regulatory Mechanism Controls Toxic Activities of PrP(C). Prion. 0. PMID 28960140 DOI: 10.1080/19336896.2017.1384894 |
0.522 |
|
| 2017 |
Bove-Fenderson E, Urano R, Straub JE, Harris DA. Cellular prion protein targets amyloid-β fibril ends via its C-terminal domain to prevent elongation. The Journal of Biological Chemistry. PMID 28842494 DOI: 10.1074/Jbc.M117.789990 |
0.432 |
|
| 2017 |
Wu B, McDonald A, Kathleen M, Rich CB, Mchugh KP, Tatzelt J, David C, Millhauser GL, Harris D. The N-terminus of the prion protein is a toxic effector regulated by the C-terminus. Elife. 6. PMID 28527237 DOI: 10.7554/Elife.23473 |
0.441 |
|
| 2017 |
Wu B, McDonald AJ, Markham K, Rich CB, McHugh KP, Tatzelt J, Colby DW, Millhauser GL, Harris DA. Author response: The N-terminus of the prion protein is a toxic effector regulated by the C-terminus Elife. DOI: 10.7554/Elife.23473.028 |
0.4 |
|
| 2016 |
Imberdis T, Heeres JT, Yueh H, Fang C, Zhen J, Rich CB, Glicksman M, Beeler A, Harris DA. Identification of Anti-Prion Compounds Using a Novel Cellular Assay. The Journal of Biological Chemistry. PMID 27803163 DOI: 10.1074/Jbc.M116.745612 |
0.417 |
|
| 2016 |
Fang C, Imberdis T, Garza MC, Wille H, Harris DA. A Neuronal Culture System to Detect Prion Synaptotoxicity. Plos Pathogens. 12: e1005623. PMID 27227882 DOI: 10.1371/journal.ppat.1005623 |
0.455 |
|
| 2016 |
Saá P, Harris DA, Cervenakova L. Mechanisms of prion-induced neurodegeneration. Expert Reviews in Molecular Medicine. 18: e5. PMID 27055367 DOI: 10.1017/erm.2016.8 |
0.444 |
|
| 2016 |
Sempou E, Biasini E, Pinzón-Olejua A, Harris DA, Málaga-Trillo E. Activation of zebrafish Src family kinases by the prion protein is an amyloid-β-sensitive signal that prevents the endocytosis and degradation of E-cadherin/β-catenin complexes in vivo. Molecular Neurodegeneration. 11: 18. PMID 26860872 DOI: 10.1186/s13024-016-0076-5 |
0.422 |
|
| 2016 |
Imberdis T, Harris DA. Synthetic Prions Provide Clues for Understanding Prion Diseases. The American Journal of Pathology. PMID 26854642 DOI: 10.1016/j.ajpath.2015.12.005 |
0.313 |
|
| 2015 |
Berney M, Berney-Meyer L, Wong KW, Chen B, Chen M, Kim J, Wang J, Harris D, Parkhill J, Chan J, Wang F, Jacobs WR. Essential roles of methionine and S-adenosylmethionine in the autarkic lifestyle of Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 26221021 DOI: 10.1073/Pnas.1513033112 |
0.317 |
|
| 2014 |
Chu NK, Shabbir W, Bove-Fenderson E, Araman C, Lemmens-Gruber R, Harris DA, Becker CF. A C-terminal membrane anchor affects the interactions of prion proteins with lipid membranes. The Journal of Biological Chemistry. 289: 30144-60. PMID 25217642 DOI: 10.1074/jbc.M114.587345 |
0.424 |
|
| 2014 |
Zeldich E, Chen CD, Colvin TA, Bove-Fenderson EA, Liang J, Tucker Zhou TB, Harris DA, Abraham CR. The neuroprotective effect of Klotho is mediated via regulation of members of the redox system. The Journal of Biological Chemistry. 289: 24700-15. PMID 25037225 DOI: 10.1074/Jbc.M114.567321 |
0.377 |
|
| 2014 |
Imberdis T, Harris DA. Prion permissive pathways: extracellular matrix genes control susceptibility to prion infection. The Embo Journal. 33: 1506-8. PMID 24952893 DOI: 10.15252/embj.201489071 |
0.308 |
|
| 2013 |
Biasini E, Unterberger U, Solomon IH, Massignan T, Senatore A, Bian H, Voigtlaender T, Bowman FP, Bonetto V, Chiesa R, Luebke J, Toselli P, Harris DA. A mutant prion protein sensitizes neurons to glutamate-induced excitotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 2408-18. PMID 23392670 DOI: 10.1523/Jneurosci.3406-12.2013 |
0.729 |
|
| 2013 |
Fluharty BR, Biasini E, Stravalaci M, Sclip A, Diomede L, Balducci C, La Vitola P, Messa M, Colombo L, Forloni G, Borsello T, Gobbi M, Harris DA. An N-terminal fragment of the prion protein binds to amyloid-β oligomers and inhibits their neurotoxicity in vivo. The Journal of Biological Chemistry. 288: 7857-66. PMID 23362282 DOI: 10.1074/jbc.M112.423954 |
0.357 |
|
| 2012 |
Biasini E, Harris DA. Targeting the cellular prion protein to treat neurodegeneration. Future Medicinal Chemistry. 4: 1655-8. PMID 22924502 DOI: 10.4155/fmc.12.114 |
0.379 |
|
| 2012 |
Turnbaugh JA, Unterberger U, Saá P, Massignan T, Fluharty BR, Bowman FP, Miller MB, Supattapone S, Biasini E, Harris DA. The N-terminal, polybasic region of PrP(C) dictates the efficiency of prion propagation by binding to PrP(Sc). The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 8817-30. PMID 22745483 DOI: 10.1523/Jneurosci.1103-12.2012 |
0.818 |
|
| 2012 |
Solomon IH, Biasini E, Harris DA. Ion channels induced by the prion protein: mediators of neurotoxicity. Prion. 6: 40-5. PMID 22453177 DOI: 10.4161/Pri.6.1.18627 |
0.737 |
|
| 2012 |
Biasini E, Turnbaugh JA, Massignan T, Veglianese P, Forloni G, Bonetto V, Chiesa R, Harris DA. The toxicity of a mutant prion protein is cell-autonomous, and can be suppressed by wild-type prion protein on adjacent cells. Plos One. 7: e33472. PMID 22428057 DOI: 10.1371/Journal.Pone.0033472 |
0.821 |
|
| 2012 |
Biasini E, Turnbaugh JA, Unterberger U, Harris DA. Prion protein at the crossroads of physiology and disease. Trends in Neurosciences. 35: 92-103. PMID 22137337 DOI: 10.1016/J.Tins.2011.10.002 |
0.815 |
|
| 2011 |
Westergard L, Turnbaugh JA, Harris DA. A naturally occurring C-terminal fragment of the prion protein (PrP) delays disease and acts as a dominant-negative inhibitor of PrPSc formation. The Journal of Biological Chemistry. 286: 44234-42. PMID 22025612 DOI: 10.1074/Jbc.M111.286195 |
0.813 |
|
| 2011 |
Turnbaugh JA, Westergard L, Unterberger U, Biasini E, Harris DA. The N-terminal, polybasic region is critical for prion protein neuroprotective activity. Plos One. 6: e25675. PMID 21980526 DOI: 10.1371/Journal.Pone.0025675 |
0.829 |
|
| 2011 |
Westergard L, Turnbaugh JA, Harris DA. A nine amino acid domain is essential for mutant prion protein toxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 14005-17. PMID 21957261 DOI: 10.1523/Jneurosci.1243-11.2011 |
0.823 |
|
| 2011 |
Solomon IH, Khatri N, Biasini E, Massignan T, Huettner JE, Harris DA. An N-terminal polybasic domain and cell surface localization are required for mutant prion protein toxicity. The Journal of Biological Chemistry. 286: 14724-36. PMID 21385869 DOI: 10.1074/Jbc.M110.214973 |
0.744 |
|
| 2011 |
Massignan T, Biasini E, Harris DA. A Drug-Based Cellular Assay (DBCA) for studying cytotoxic and cytoprotective activities of the prion protein: A practical guide. Methods (San Diego, Calif.). 53: 214-9. PMID 21115124 DOI: 10.1016/j.ymeth.2010.11.005 |
0.538 |
|
| 2010 |
Solomon IH, Huettner JE, Harris DA. Neurotoxic mutants of the prion protein induce spontaneous ionic currents in cultured cells. The Journal of Biological Chemistry. 285: 26719-26. PMID 20573963 DOI: 10.1074/Jbc.M110.134619 |
0.729 |
|
| 2010 |
Christensen HM, Dikranian K, Li A, Baysac KC, Walls KC, Olney JW, Roth KA, Harris DA. A highly toxic cellular prion protein induces a novel, nonapoptotic form of neuronal death. The American Journal of Pathology. 176: 2695-706. PMID 20472884 DOI: 10.2353/Ajpath.2010.091007 |
0.729 |
|
| 2010 |
Li M, Husic N, Lin Y, Christensen H, Malik I, McIver S, LaPash Daniels CM, Harris DA, Kotzbauer PT, Goldberg MP, Snider BJ. Optimal promoter usage for lentiviral vector-mediated transduction of cultured central nervous system cells. Journal of Neuroscience Methods. 189: 56-64. PMID 20347873 DOI: 10.1016/J.Jneumeth.2010.03.019 |
0.695 |
|
| 2010 |
Massignan T, Biasini E, Lauranzano E, Veglianese P, Pignataro M, Fioriti L, Harris DA, Salmona M, Chiesa R, Bonetto V. Mutant prion protein expression is associated with an alteration of the Rab GDP dissociation inhibitor alpha (GDI)/Rab11 pathway. Molecular & Cellular Proteomics : McP. 9: 611-22. PMID 19996123 DOI: 10.1074/mcp.M900271-MCP200 |
0.511 |
|
| 2010 |
Massignan T, Stewart RS, Biasini E, Solomon IH, Bonetto V, Chiesa R, Harris DA. A novel, drug-based, cellular assay for the activity of neurotoxic mutants of the prion protein. The Journal of Biological Chemistry. 285: 7752-65. PMID 19940127 DOI: 10.1074/Jbc.M109.064949 |
0.76 |
|
| 2010 |
Solomon IH, Schepker JA, Harris DA. Prion neurotoxicity: insights from prion protein mutants. Current Issues in Molecular Biology. 12: 51-61. PMID 19767650 |
0.736 |
|
| 2009 |
Biasini E, Tapella L, Mantovani S, Stravalaci M, Gobbi M, Harris DA, Chiesa R. Immunopurification of pathological prion protein aggregates. Plos One. 4: e7816. PMID 19915706 DOI: 10.1371/journal.pone.0007816 |
0.534 |
|
| 2009 |
Jackson AP, Gamble JA, Yeomans T, Moran GP, Saunders D, Harris D, Aslett M, Barrell JF, Butler G, Citiulo F, Coleman DC, de Groot PW, Goodwin TJ, Quail MA, McQuillan J, et al. Comparative genomics of the fungal pathogens Candida dubliniensis and Candida albicans. Genome Research. 19: 2231-44. PMID 19745113 DOI: 10.1101/Gr.097501.109 |
0.324 |
|
| 2009 |
Jeffrey M, Goodsir C, McGovern G, Barmada SJ, Medrano AZ, Harris DA. Prion protein with an insertional mutation accumulates on axonal and dendritic plasmalemma and is associated with distinctive ultrastructural changes. The American Journal of Pathology. 175: 1208-17. PMID 19700753 DOI: 10.2353/Ajpath.2009.090125 |
0.722 |
|
| 2009 |
Chiesa R, Harris DA. Fishing for prion protein function. Plos Biology. 7: e75. PMID 19338390 DOI: 10.1371/journal.pbio.1000075 |
0.544 |
|
| 2009 |
Christensen HM, Harris DA. A deleted prion protein that is neurotoxic in vivo is localized normally in cultured cells. Journal of Neurochemistry. 108: 44-56. PMID 19046329 DOI: 10.1111/J.1471-4159.2008.05719.X |
0.778 |
|
| 2008 |
Chiesa R, Piccardo P, Biasini E, Ghetti B, Harris DA. Aggregated, wild-type prion protein causes neurological dysfunction and synaptic abnormalities. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 13258-67. PMID 19052217 DOI: 10.1523/JNEUROSCI.3109-08.2008 |
0.527 |
|
| 2008 |
Christensen HM, Harris DA. Prion protein lacks robust cytoprotective activity in cultured cells. Molecular Neurodegeneration. 3: 11. PMID 18718018 DOI: 10.1186/1750-1326-3-11 |
0.738 |
|
| 2008 |
Greil CS, Vorberg IM, Ward AE, Meade-White KD, Harris DA, Priola SA. Acute cellular uptake of abnormal prion protein is cell type and scrapie-strain independent. Virology. 379: 284-93. PMID 18692214 DOI: 10.1016/J.Virol.2008.07.006 |
0.493 |
|
| 2008 |
Medrano AZ, Barmada SJ, Biasini E, Harris DA. GFP-tagged mutant prion protein forms intra-axonal aggregates in transgenic mice. Neurobiology of Disease. 31: 20-32. PMID 18514536 DOI: 10.1016/J.Nbd.2008.03.006 |
0.718 |
|
| 2008 |
Biasini E, Seegulam ME, Patti BN, Solforosi L, Medrano AZ, Christensen HM, Senatore A, Chiesa R, Williamson RA, Harris DA. Non-infectious aggregates of the prion protein react with several PrPSc-directed antibodies. Journal of Neurochemistry. 105: 2190-204. PMID 18298665 DOI: 10.1111/J.1471-4159.2008.05306.X |
0.711 |
|
| 2008 |
Biasini E, Medrano AZ, Thellung S, Chiesa R, Harris DA. Multiple biochemical similarities between infectious and non-infectious aggregates of a prion protein carrying an octapeptide insertion. Journal of Neurochemistry. 104: 1293-308. PMID 18034781 DOI: 10.1111/j.1471-4159.2007.05082.x |
0.518 |
|
| 2008 |
Harris D, Huselton E, Chernin M. Induced protein expression in murine osteoblast cells (MC3T3) by a synthetic angiotensin II gene The Faseb Journal. 22: 206-206. DOI: 10.1096/Fasebj.22.2_Supplement.206 |
0.328 |
|
| 2007 |
Dong J, Li A, Yamaguchi N, Sakaguchi S, Harris DA. Doppel induces degeneration of cerebellar Purkinje cells independently of Bax. The American Journal of Pathology. 171: 599-607. PMID 17569776 DOI: 10.2353/ajpath.2007.070262 |
0.477 |
|
| 2007 |
Tank EM, Harris DA, Desai AA, True HL. Prion protein repeat expansion results in increased aggregation and reveals phenotypic variability. Molecular and Cellular Biology. 27: 5445-55. PMID 17548473 DOI: 10.1128/MCB.02127-06 |
0.486 |
|
| 2007 |
Li A, Piccardo P, Barmada SJ, Ghetti B, Harris DA. Prion protein with an octapeptide insertion has impaired neuroprotective activity in transgenic mice. The Embo Journal. 26: 2777-85. PMID 17510630 DOI: 10.1038/Sj.Emboj.7601726 |
0.731 |
|
| 2007 |
Yin S, Pham N, Yu S, Li C, Wong P, Chang B, Kang SC, Biasini E, Tien P, Harris DA, Sy MS. Human prion proteins with pathogenic mutations share common conformational changes resulting in enhanced binding to glycosaminoglycans. Proceedings of the National Academy of Sciences of the United States of America. 104: 7546-51. PMID 17456603 DOI: 10.1073/pnas.0610827104 |
0.47 |
|
| 2007 |
Westergard L, Christensen HM, Harris DA. The cellular prion protein (PrP(C)): its physiological function and role in disease. Biochimica Et Biophysica Acta. 1772: 629-44. PMID 17451912 DOI: 10.1016/J.Bbadis.2007.02.011 |
0.746 |
|
| 2007 |
Li A, Barmada SJ, Roth KA, Harris DA. N-terminally deleted forms of the prion protein activate both Bax-dependent and Bax-independent neurotoxic pathways. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 852-9. PMID 17251426 DOI: 10.1523/Jneurosci.4244-06.2007 |
0.732 |
|
| 2007 |
Li A, Christensen HM, Stewart LR, Roth KA, Chiesa R, Harris DA. Neonatal lethality in transgenic mice expressing prion protein with a deletion of residues 105-125. The Embo Journal. 26: 548-58. PMID 17245437 DOI: 10.1038/Sj.Emboj.7601507 |
0.758 |
|
| 2006 |
Harris DA, True HL. New insights into prion structure and toxicity. Neuron. 50: 353-7. PMID 16675391 DOI: 10.1016/j.neuron.2006.04.020 |
0.478 |
|
| 2005 |
Barmada SJ, Harris DA. Visualization of prion infection in transgenic mice expressing green fluorescent protein-tagged prion protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 5824-32. PMID 15958749 DOI: 10.1523/Jneurosci.1192-05.2005 |
0.712 |
|
| 2005 |
Stewart RS, Piccardo P, Ghetti B, Harris DA. Neurodegenerative illness in transgenic mice expressing a transmembrane form of the prion protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 3469-77. PMID 15800202 DOI: 10.1523/JNEUROSCI.0105-05.2005 |
0.551 |
|
| 2005 |
Li A, Harris DA. Mammalian prion protein suppresses Bax-induced cell death in yeast. The Journal of Biological Chemistry. 280: 17430-4. PMID 15753097 DOI: 10.1074/jbc.C500058200 |
0.509 |
|
| 2005 |
Stewart RS, Harris DA. A transmembrane form of the prion protein is localized in the Golgi apparatus of neurons. The Journal of Biological Chemistry. 280: 15855-64. PMID 15671025 DOI: 10.1074/jbc.M412298200 |
0.438 |
|
| 2005 |
Fioriti L, Dossena S, Stewart LR, Stewart RS, Harris DA, Forloni G, Chiesa R. Cytosolic prion protein (PrP) is not toxic in N2a cells and primary neurons expressing pathogenic PrP mutations. The Journal of Biological Chemistry. 280: 11320-8. PMID 15632159 DOI: 10.1074/jbc.M412441200 |
0.535 |
|
| 2005 |
Chiesa R, Piccardo P, Dossena S, Nowoslawski L, Roth KA, Ghetti B, Harris DA. Bax deletion prevents neuronal loss but not neurological symptoms in a transgenic model of inherited prion disease. Proceedings of the National Academy of Sciences of the United States of America. 102: 238-43. PMID 15618403 DOI: 10.1073/pnas.0406173102 |
0.456 |
|
| 2005 |
Fioriti L, Quaglio E, Massignan T, Colombo L, Stewart RS, Salmona M, Harris DA, Forloni G, Chiesa R. The neurotoxicity of prion protein (PrP) peptide 106-126 is independent of the expression level of PrP and is not mediated by abnormal PrP species. Molecular and Cellular Neurosciences. 28: 165-76. PMID 15607951 DOI: 10.1016/j.mcn.2004.09.006 |
0.498 |
|
| 2004 |
Barmada S, Piccardo P, Yamaguchi K, Ghetti B, Harris DA. GFP-tagged prion protein is correctly localized and functionally active in the brains of transgenic mice. Neurobiology of Disease. 16: 527-37. PMID 15262264 DOI: 10.1016/J.Nbd.2004.05.005 |
0.734 |
|
| 2004 |
Li A, Dong J, Harris DA. Cell surface expression of the prion protein in yeast does not alter copper utilization phenotypes. The Journal of Biological Chemistry. 279: 29469-77. PMID 15090539 DOI: 10.1074/jbc.M402517200 |
0.487 |
|
| 2003 |
Harris DA. Trafficking, turnover and membrane topology of PrP. British Medical Bulletin. 66: 71-85. PMID 14522850 DOI: 10.1093/bmb/66.1.71 |
0.494 |
|
| 2003 |
Brown LR, Harris DA. Copper and zinc cause delivery of the prion protein from the plasma membrane to a subset of early endosomes and the Golgi. Journal of Neurochemistry. 87: 353-63. PMID 14511113 DOI: 10.1046/j.1471-4159.2003.01996.x |
0.377 |
|
| 2003 |
Stewart RS, Harris DA. Mutational analysis of topological determinants in prion protein (PrP) and measurement of transmembrane and cytosolic PrP during prion infection. The Journal of Biological Chemistry. 278: 45960-8. PMID 12933795 DOI: 10.1074/jbc.M307833200 |
0.431 |
|
| 2003 |
Chiesa R, Piccardo P, Quaglio E, Drisaldi B, Si-Hoe SL, Takao M, Ghetti B, Harris DA. Molecular distinction between pathogenic and infectious properties of the prion protein. Journal of Virology. 77: 7611-22. PMID 12805461 DOI: 10.1128/JVI.77.13.7611-7622.2003 |
0.531 |
|
| 2003 |
Deleault NR, Dolph PJ, Feany MB, Cook ME, Nishina K, Harris DA, Supattapone S. Post-transcriptional suppression of pathogenic prion protein expression in Drosophila neurons. Journal of Neurochemistry. 85: 1614-23. PMID 12787080 DOI: 10.1046/J.1471-4159.2003.01819.X |
0.494 |
|
| 2003 |
Harris DA, Chiesa R, Drisaldi B, Quaglio E, Migheli A, Piccardo P, Ghetti B. A murine model of a familial prion disease. Clinics in Laboratory Medicine. 23: 175-86. PMID 12733431 DOI: 10.1016/S0272-2712(02)00069-0 |
0.498 |
|
| 2003 |
Drisaldi B, Stewart RS, Adles C, Stewart LR, Quaglio E, Biasini E, Fioriti L, Chiesa R, Harris DA. Mutant PrP is delayed in its exit from the endoplasmic reticulum, but neither wild-type nor mutant PrP undergoes retrotranslocation prior to proteasomal degradation. The Journal of Biological Chemistry. 278: 21732-43. PMID 12663673 DOI: 10.1074/jbc.M213247200 |
0.511 |
|
| 2002 |
Mangé A, Milhavet O, Umlauf D, Harris D, Lehmann S. PrP-dependent cell adhesion in N2a neuroblastoma cells Febs Letters. 514: 159-162. PMID 11943143 DOI: 10.1016/S0014-5793(02)02338-4 |
0.451 |
|
| 2001 |
Harris DA, Chiesa R, Migheli A, Piccardo P, Ghetti B. Cellular and transgenic models of familial prion diseases. Methods in Molecular Medicine. 59: 149-61. PMID 21374503 DOI: 10.1385/1-59259-134-5:149 |
0.455 |
|
| 2001 |
Chiesa R, Harris DA. Prion diseases: what is the neurotoxic molecule? Neurobiology of Disease. 8: 743-63. PMID 11592845 DOI: 10.1006/nbdi.2001.0433 |
0.452 |
|
| 2001 |
Ivanova L, Barmada S, Kummer T, Harris DA. Mutant prion proteins are partially retained in the endoplasmic reticulum. The Journal of Biological Chemistry. 276: 42409-21. PMID 11527974 DOI: 10.1074/Jbc.M106928200 |
0.724 |
|
| 2001 |
Harris DA. Biosynthesis and cellular processing of the prion protein. Advances in Protein Chemistry. 57: 203-28. PMID 11447691 DOI: 10.1016/S0065-3233(01)57023-0 |
0.371 |
|
| 2001 |
Chiesa R, Pestronk A, Schmidt RE, Tourtellotte WG, Ghetti B, Piccardo P, Harris DA. Primary myopathy and accumulation of PrPSc-like molecules in peripheral tissues of transgenic mice expressing a prion protein insertional mutation. Neurobiology of Disease. 8: 279-88. PMID 11300723 DOI: 10.1006/Nbdi.2001.0400 |
0.494 |
|
| 2001 |
Stewart RS, Drisaldi B, Harris DA. A transmembrane form of the prion protein contains an uncleaved signal peptide and is retained in the endoplasmic Reticulum. Molecular Biology of the Cell. 12: 881-9. PMID 11294893 DOI: 10.1091/Mbc.12.4.881 |
0.458 |
|
| 2001 |
Quaglio E, Chiesa R, Harris DA. Copper converts the cellular prion protein into a protease-resistant species that is distinct from the scrapie isoform. The Journal of Biological Chemistry. 276: 11432-8. PMID 11278539 DOI: 10.1074/jbc.M009666200 |
0.453 |
|
| 2001 |
Stewart RS, Harris DA. Most pathogenic mutations do not alter the membrane topology of the prion protein. The Journal of Biological Chemistry. 276: 2212-20. PMID 11053411 DOI: 10.1074/jbc.M006763200 |
0.446 |
|
| 2000 |
Harris DA, Chiesa R, Drisaldi B, Quaglio E, Migheli A, Piccardo P, Ghetti B. A transgenic model of a familial prion disease. Archives of Virology. Supplementum. 103-12. PMID 11214912 DOI: 10.1007/978-3-7091-6308-5_9 |
0.501 |
|
| 2000 |
Chiesa R, Harris DA. Nerve growth factor-induced differentiation does not alter the biochemical properties of a mutant prion protein expressed in PC12 cells. Journal of Neurochemistry. 75: 72-80. PMID 10854249 DOI: 10.1046/j.1471-4159.2000.0750072.x |
0.499 |
|
| 2000 |
Chiesa R, Drisaldi B, Quaglio E, Migheli A, Piccardo P, Ghetti B, Harris DA. Accumulation of protease-resistant prion protein (PrP) and apoptosis of cerebellar granule cells in transgenic mice expressing a PrP insertional mutation. Proceedings of the National Academy of Sciences of the United States of America. 97: 5574-9. PMID 10805813 DOI: 10.1073/pnas.97.10.5574 |
0.524 |
|
| 2000 |
Waggoner DJ, Drisaldi B, Bartnikas TB, Casareno RL, Prohaska JR, Gitlin JD, Harris DA. Brain copper content and cuproenzyme activity do not vary with prion protein expression level. The Journal of Biological Chemistry. 275: 7455-8. PMID 10713045 DOI: 10.1074/Jbc.275.11.7455 |
0.427 |
|
| 2000 |
Soto C, Kascsak RJ, SaborÃo GP, Aucouturier P, Wisniewski T, Prelli F, Kascsak R, Mendez E, Harris DA, Ironside J, Tagliavini F, Carp RI, Frangione B. Reversion of prion protein conformational changes by synthetic beta-sheet breaker peptides. Lancet. 355: 192-7. PMID 10675119 DOI: 10.1016/S0140-6736(99)11419-3 |
0.326 |
|
| 2000 |
Nishida N, Harris DA, Vilette D, Laude H, Frobert Y, Grassi J, Casanova D, Milhavet O, Lehmann S. Successful transmission of three mouse-adapted scrapie strains to murine neuroblastoma cell lines overexpressing wild-type mouse prion protein. Journal of Virology. 74: 320-5. PMID 10590120 DOI: 10.1128/Jvi.74.1.320-325.2000 |
0.373 |
|
| 1999 |
Harris DA. Cell biological studies of the prion protein. Current Issues in Molecular Biology. 1: 65-75. PMID 11475702 |
0.357 |
|
| 1999 |
Harris DA. Cellular biology of prion diseases. Clinical Microbiology Reviews. 12: 429-44. PMID 10398674 DOI: 10.1128/Cmr.12.3.429 |
0.405 |
|
| 1999 |
Narwa R, Harris DA. Prion proteins carrying pathogenic mutations are resistant to phospholipase cleavage of their glycolipid anchors. Biochemistry. 38: 8770-7. PMID 10393552 DOI: 10.1021/bi990736c |
0.488 |
|
| 1999 |
SaborÃo GP, Soto C, Kascsak RJ, Levy E, Kascsak R, Harris DA, Frangione B. Cell-lysate conversion of prion protein into its protease-resistant isoform suggests the participation of a cellular chaperone. Biochemical and Biophysical Research Communications. 258: 470-5. PMID 10329411 DOI: 10.1006/Bbrc.1999.0660 |
0.536 |
|
| 1998 |
Chiesa R, Piccardo P, Ghetti B, Harris DA. Neurological illness in transgenic mice expressing a prion protein with an insertional mutation. Neuron. 21: 1339-51. PMID 9883727 DOI: 10.1016/S0896-6273(00)80653-4 |
0.512 |
|
| 1998 |
Pauly PC, Harris DA. Copper stimulates endocytosis of the prion protein. The Journal of Biological Chemistry. 273: 33107-10. PMID 9837873 DOI: 10.1074/jbc.273.50.33107 |
0.385 |
|
| 1997 |
Lehmann S, Daude N, Harris DA. A wild-type prion protein does not acquire properties of the scrapie isoform when coexpressed with a mutant prion protein in cultured cells. Brain Research. Molecular Brain Research. 52: 139-45. PMID 9450686 DOI: 10.1016/S0169-328X(97)00231-3 |
0.531 |
|
| 1997 |
Lehmann S, Harris DA. Blockade of glycosylation promotes acquisition of scrapie-like properties by the prion protein in cultured cells. The Journal of Biological Chemistry. 272: 21479-87. PMID 9261166 DOI: 10.1074/jbc.272.34.21479 |
0.468 |
|
| 1997 |
Lehmann S, Chiesa R, Harris DA. Evidence for a six-transmembrane domain structure of presenilin 1. The Journal of Biological Chemistry. 272: 12047-51. PMID 9115271 DOI: 10.1074/jbc.272.18.12047 |
0.415 |
|
| 1997 |
Daude N, Lehmann S, Harris DA. Identification of intermediate steps in the conversion of a mutant prion protein to a scrapie-like form in cultured cells. The Journal of Biological Chemistry. 272: 11604-12. PMID 9111077 DOI: 10.1074/jbc.272.17.11604 |
0.491 |
|
| 1996 |
Lehmann S, Harris DA. Two mutant prion proteins expressed in cultured cells acquire biochemical properties reminiscent of the scrapie isoform. Proceedings of the National Academy of Sciences of the United States of America. 93: 5610-4. PMID 8643624 DOI: 10.1073/pnas.93.11.5610 |
0.53 |
|
| 1996 |
Lehmann S, Harris DA. Mutant and infectious prion proteins display common biochemical properties in cultured cells. The Journal of Biological Chemistry. 271: 1633-7. PMID 8576163 DOI: 10.1074/jbc.271.3.1633 |
0.509 |
|
| 1996 |
Harris DA, Gorodinsky A, Lehmann S, Moulder K, Shyng SL. Cell biology of the prion protein. Current Topics in Microbiology and Immunology. 207: 77-93. PMID 8575208 DOI: 10.1007/978-3-642-60983-1_7 |
0.624 |
|
| 1995 |
Shyng SL, Lehmann S, Moulder KL, Harris DA. Sulfated glycans stimulate endocytosis of the cellular isoform of the prion protein, PrPC, in cultured cells. The Journal of Biological Chemistry. 270: 30221-9. PMID 8530433 DOI: 10.1074/Jbc.270.50.30221 |
0.693 |
|
| 1995 |
Shyng SL, Moulder KL, Lesko A, Harris DA. The N-terminal domain of a glycolipid-anchored prion protein is essential for its endocytosis via clathrin-coated pits. The Journal of Biological Chemistry. 270: 14793-800. PMID 7782345 DOI: 10.1074/jbc.270.24.14793 |
0.679 |
|
| 1995 |
Lehmann S, Harris DA. A mutant prion protein displays an aberrant membrane association when expressed in cultured cells. The Journal of Biological Chemistry. 270: 24589-97. PMID 7592679 DOI: 10.1074/jbc.270.41.24589 |
0.477 |
|
| 1995 |
Gorodinsky A, Harris DA. Glycolipid-anchored proteins in neuroblastoma cells form detergent-resistant complexes without caveolin. The Journal of Cell Biology. 129: 619-27. PMID 7537273 DOI: 10.1083/jcb.129.3.619 |
0.38 |
|
| 1994 |
Shyng SL, Heuser JE, Harris DA. A glycolipid-anchored prion protein is endocytosed via clathrin-coated pits. The Journal of Cell Biology. 125: 1239-50. PMID 7911471 DOI: 10.1083/jcb.125.6.1239 |
0.639 |
|
| 1993 |
Harris DA, Lele P, Snider WD. Localization of the mRNA for a chicken prion protein by in situ hybridization. Proceedings of the National Academy of Sciences of the United States of America. 90: 4309-13. PMID 8483948 DOI: 10.1073/Pnas.90.9.4309 |
0.372 |
|
| 1993 |
Shyng SL, Huber MT, Harris DA. A prion protein cycles between the cell surface and an endocytic compartment in cultured neuroblastoma cells. The Journal of Biological Chemistry. 268: 15922-8. PMID 8101844 |
0.612 |
|
| 1993 |
Harris DA, Huber MT, van Dijken P, Shyng SL, Chait BT, Wang R. Processing of a cellular prion protein: identification of N- and C-terminal cleavage sites. Biochemistry. 32: 1009-16. PMID 8093841 DOI: 10.1021/Bi00055A003 |
0.669 |
|
| 1991 |
Harris DA, Falls DL, Johnson FA, Fischbach GD. A prion-like protein from chicken brain copurifies with an acetylcholine receptor-inducing activity. Proceedings of the National Academy of Sciences of the United States of America. 88: 7664-8. PMID 1715573 DOI: 10.1073/pnas.88.17.7664 |
0.405 |
|
| 1984 |
HARRIS DA, SHERBANY AA, SCHWARTZ JH. PURIFICATION AND CHARACTERIZATION OF MUSCLE PROTEINS FROMAPLYSIA CALIFORNICA The Biological Bulletin. 166: 482-493. DOI: 10.2307/1541156 |
0.307 |
|
| 1981 |
Harris DA, Schwartz JH. Characterization of brevin, a serum protein that shortens actin filaments. Proceedings of the National Academy of Sciences of the United States of America. 78: 6798-802. PMID 6947253 DOI: 10.1073/pnas.78.11.6798 |
0.323 |
|
| Show low-probability matches. |