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Barry J. Hoffer - Publications

Affiliations: 
National Institute on Drug Abuse 
Area:
Pharmacology
Website:
http://www.drugabuse.gov/DIR/cell-neuro.html

325 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Lecca D, Bader M, Tweedie D, Hoffman AF, Jung YJ, Hsueh SC, Hoffer BJ, Becker RE, Pick CG, Lupica CR, Greig NH. (-)-Phenserine and the prevention of pre-programmed cell death and neuroinflammation in mild traumatic brain injury and Alzheimer's disease challenged mice. Neurobiology of Disease. 104528. PMID 31295555 DOI: 10.1016/j.nbd.2019.104528  0.84
2019 Lai JH, Chen KY, Chung-Che Wu J, Olson L, Brené S, Huang CZ, Chen YH, Kang SJ, Ma KH, Hoffer BJ, Hsieh TH, Chiang YH. Voluntary exercise delays progressive deterioration of markers of metabolism and behavior in a mouse model of Parkinson's disease. Brain Research. 146301. PMID 31226324 DOI: 10.1016/j.brainres.2019.146301  1
2019 Hsueh SC, Lecca D, Greig NH, Wang JY, Selman W, Hoffer BJ, Miller JP, Chiang YH. (-)-Phenserine Ameliorates Contusion Volume, Neuroinflammation, and Behavioral Impairments Induced by Traumatic Brain Injury in Mice. Cell Transplantation. 963689719854693. PMID 31177840 DOI: 10.1177/0963689719854693  0.4
2019 Hartman JH, Richie CT, Gordon KL, Mello DF, Castillo P, Zhu A, Wang Y, Hoffer BJ, Sherwood DR, Meyer JN, Harvey BK. MANF deletion abrogates early larval Caenorhabditis elegans stress response to tunicamycin and Pseudomonas aeruginosa. European Journal of Cell Biology. PMID 31138438 DOI: 10.1016/j.ejcb.2019.05.002  0.72
2019 Tsai YR, Tweedie D, Navas-Enamorado I, Scerba MT, Chang CF, Lai JH, Wu JC, Chen YH, Kang SJ, Hoffer BJ, de Cabo R, Greig NH, Chiang YH, Chen KY. Pomalidomide Reduces Ischemic Brain Injury in Rodents. Cell Transplantation. 963689719850078. PMID 31094216 DOI: 10.1177/0963689719850078  0.4
2019 Chen YH, Hsieh TH, Kuo TT, Kao JH, Ma KH, Huang EY, Chou YC, Olson L, Hoffer BJ. Release parameters during progressive degeneration of dopamine neurons in mouse model reveal earlier impairment of spontaneous than forced behaviors. Journal of Neurochemistry. PMID 30933310 DOI: 10.1111/jnc.14702  1
2018 Tsai YR, Chang CF, Lai JH, Wu JC, Chen YH, Kang SJ, Hoffer BJ, Tweedie D, Luo W, Greig NH, Chiang YH, Chen KY. Pomalidomide Ameliorates H₂O₂-Induced Oxidative Stress Injury and Cell Death in Rat Primary Cortical Neuronal Cultures by Inducing Anti-Oxidative and Anti-Apoptosis Effects. International Journal of Molecular Sciences. 19. PMID 30347766 DOI: 10.3390/ijms19103252  0.4
2018 Lai JH, Karlsson TE, Wu JC, Huang CZ, Chen YH, Kang SJ, Brodin ATS, Hoffer BJ, Olson L, Chiang YH, Chen KY. Role of Nogo receptor-1 for recovery of balance, cognition and emotion after mild traumatic brain injury in mice. Journal of Neurotrauma. PMID 30226403 DOI: 10.1089/neu.2018.5949  1
2018 Chen S, Yu SJ, Li Y, Lecca D, Glotfelty E, Kim HK, Choi HI, Hoffer BJ, Greig NH, Kim DS, Wang Y. Author Correction: Post-treatment with PT302, a long-acting Exendin-4 sustained release formulation, reduces dopaminergic neurodegeneration in a 6-Hydroxydopamine rat model of Parkinson's disease. Scientific Reports. 8: 13953. PMID 30209317 DOI: 10.1038/s41598-018-31455-w  0.64
2018 Chen S, Yu SJ, Li Y, Lecca D, Glotfelty E, Kim HK, Choi HI, Hoffer BJ, Greig NH, Kim DS, Wang Y. Post-treatment with PT302, a long-acting Exendin-4 sustained release formulation, reduces dopaminergic neurodegeneration in a 6-Hydroxydopamine rat model of Parkinson's disease. Scientific Reports. 8: 10722. PMID 30013201 DOI: 10.1038/s41598-018-28449-z  0.64
2018 Yuan-Hao C, Kuo TT, Huang EY, Hoffer BJ, Kao JH, Chou YC, Chiang YH, Miller J. Nicotine-induced Conditional Place Preference is Affected by Head Injury: Correlation with Dopamine Release in the Nucleus Accumbens Shell. The International Journal of Neuropsychopharmacology. PMID 29905798 DOI: 10.1093/ijnp/pyy055  0.4
2018 Yu YW, Hsueh SC, Lai JH, Chen YH, Kang SJ, Chen KY, Hsieh TH, Hoffer BJ, Li Y, Greig NH, Chiang YH. Glucose-Dependent Insulinotropic Polypeptide Mitigates 6-OHDA-Induced Behavioral Impairments in Parkinsonian Rats. International Journal of Molecular Sciences. 19. PMID 29641447 DOI: 10.3390/ijms19041153  0.4
2018 Chen YH, Kuo TT, Yi-Kung Huang E, Hoffer BJ, Chou YC, Chiang YH, Ma HI, Miller JP. Profound deficits in hippocampal synaptic plasticity after traumatic brain injury and seizure is ameliorated by prophylactic levetiracetam. Oncotarget. 9: 11515-11527. PMID 29545916 DOI: 10.18632/oncotarget.23923  0.4
2018 Chen YH, Kuo TT, Yi-Kung Huang E, Chou YC, Chiang YH, Hoffer BJ, Miller J. Effect of traumatic brain injury on nicotine-induced modulation of dopamine release in the striatum and nucleus accumbens shell. Oncotarget. 9: 10016-10028. PMID 29515787 DOI: 10.18632/oncotarget.24245  0.4
2017 Kim DS, Choi HI, Wang Y, Luo Y, Hoffer BJ, Greig NH. A New Treatment Strategy for Parkinson's Disease through the Gut-Brain Axis: The Glucagon-Like Peptide-1 Receptor Pathway. Cell Transplantation. 26: 1560-1571. PMID 29113464 DOI: 10.1177/0963689717721234  0.64
2017 Chen YH, Huang EY, Kuo TT, Miller J, Chiang YH, Hoffer BJ. Impact of Traumatic Brain Injury on Dopaminergic Transmission. Cell Transplantation. 26: 1156-1168. PMID 28933212 DOI: 10.1177/0963689717714105  0.4
2017 Hoffer BJ, Pick CG, Hoffer ME, Becker RE, Chiang YH, Greig NH. Repositioning drugs for traumatic brain injury - N-acetyl cysteine and Phenserine. Journal of Biomedical Science. 24: 71. PMID 28886718 DOI: 10.1186/s12929-017-0377-1  0.4
2017 Kim DS, Choi HI, Wang Y, Luo Y, Hoffer BJ, Greig NH. A New Treatment Strategy for Parkinson's Disease Through the Gut-Brain Axis: The Glucagon-like Peptide-1 Receptor Pathway. Cell Transplantation. PMID 28447569 DOI: 10.3727/096368917X695669  0.64
2017 Chen YH, Huang EY, Kuo TT, Hoffer BJ, Miller J, Chou YC, Chiang YH. Dopamine release in the nucleus accumbens is altered following traumatic brain injury. Neuroscience. PMID 28196657 DOI: 10.1016/j.neuroscience.2017.02.001  0.4
2016 Wang JY, Huang YN, Chiu CC, Tweedie D, Luo W, Pick CG, Chou SY, Luo Y, Hoffer BJ, Greig NH, Wang JY. Erratum to: Pomalidomide mitigates neuronal loss, neuroinflammation, and behavioral impairments induced by traumatic brain injury in rat. Journal of Neuroinflammation. 13: 228. PMID 27616060 DOI: 10.1186/s12974-016-0668-6  0.48
2016 Yang LY, Greig NH, Huang YN, Hsieh TH, Tweedie D, Yu QS, Hoffer BJ, Luo Y, Kao YC, Wang JY. Post-traumatic administration of the p53 inactivator pifithrin-α oxygen analogue reduces hippocampal neuronal loss and improves cognitive deficits after experimental traumatic brain injury. Neurobiology of Disease. PMID 27553877 DOI: 10.1016/j.nbd.2016.08.012  0.48
2016 Wang JY, Huang YN, Chiu CC, Tweedie D, Luo W, Pick CG, Chou SY, Luo Y, Hoffer BJ, Greig NH, Wang JY. Pomalidomide mitigates neuronal loss, neuroinflammation, and behavioral impairments induced by traumatic brain injury in rat. Journal of Neuroinflammation. 13: 168. PMID 27353053 DOI: 10.1186/s12974-016-0631-6  1
2016 Tweedie D, Fukui K, Li Y, Yu QS, Barak S, Tamargo IA, Rubovitch V, Holloway HW, Lehrmann E, Wood WH, Zhang Y, Becker KG, Perez E, Van Praag H, Luo Y, ... Hoffer BJ, et al. Cognitive Impairments Induced by Concussive Mild Traumatic Brain Injury in Mouse Are Ameliorated by Treatment with Phenserine via Multiple Non-Cholinergic and Cholinergic Mechanisms. Plos One. 11: e0156493. PMID 27254111 DOI: 10.1371/journal.pone.0156493  0.64
2016 Chen YH, Huang EY, Kuo TT, Hoffer BJ, Wu PJ, Ma HI, Tsai JJ, Chou YC, Chiang YH. Levetiracetam prophylaxis ameliorates seizure epileptogenesis after fluid percussion injury. Brain Research. 1642: 581-9. PMID 27106270 DOI: 10.1016/j.brainres.2016.04.013  0.4
2016 Sheng Y, Filichia E, Shick E, Preston KL, Phillips KA, Cooperman L, Lin Z, Tesar P, Hoffer BJ, Luo Y. Lower Dopamine D2 Receptor Expression Levels in Human Dopaminergic Neurons Derived From Opioid-Dependent iPSCs. The American Journal of Psychiatry. 173: 429-431. PMID 27035534 DOI: 10.1176/appi.ajp.2015.15121545  0.48
2016 Yu YW, Hsieh TH, Chen KY, Wu JC, Hoffer B, Greig NH, Li Y, Lai JH, Chang CF, Lin JW, Chen YH, Yang LY, Chiang YH. Glucose-dependent insulinotropic polypeptide ameliorates mild traumatic brain injury-induced cognitive and sensorimotor deficits and neuroinflammation in rats. Journal of Neurotrauma. PMID 26972789 DOI: 10.1089/neu.2015.4229  0.4
2016 Liu HS, Shen H, Luo Y, Hoffer BJ, Wang Y, Yang Y. Post-treatment with cocaine- and amphetamine-regulated transcript enhances infarct resolution, reinnervation, and angiogenesis in stroke rats - an MRI study. Nmr in Biomedicine. 29: 361-70. PMID 26915794 DOI: 10.1002/nbm.3461  0.64
2015 Tweedie D, Rachmany L, Rubovitch V, Li Y, Holloway HW, Lehrmann E, Zhang Y, Becker KG, Perez E, Hoffer BJ, Pick CG, Greig NH. Blast traumatic brain injury-induced cognitive deficits are attenuated by preinjury or postinjury treatment with the glucagon-like peptide-1 receptor agonist, exendin-4. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26327236 DOI: 10.1016/j.jalz.2015.07.489  0.64
2015 Shan L, Diaz O, Zhang Y, Ladenheim B, Cadet JL, Chiang YH, Olson L, Hoffer BJ, Bäckman CM. l-Dopa induced dyskinesias in Parkinsonian mice: Disease severity or l-Dopa history. Brain Research. PMID 26086365 DOI: 10.1016/j.brainres.2015.06.005  1
2015 Baratz R, Tweedie D, Wang JY, Rubovitch V, Luo W, Hoffer BJ, Greig NH, Pick CG. Transiently lowering tumor necrosis factor-α synthesis ameliorates neuronal cell loss and cognitive impairments induced by minimal traumatic brain injury in mice. Journal of Neuroinflammation. 12: 45. PMID 25879458 DOI: 10.1186/s12974-015-0237-4  1
2015 Yang LY, Chu YH, Tweedie D, Yu QS, Pick CG, Hoffer BJ, Greig NH, Wang JY. Post-trauma administration of the pifithrin-α oxygen analog improves histological and functional outcomes after experimental traumatic brain injury. Experimental Neurology. 269: 56-66. PMID 25819102 DOI: 10.1016/j.expneurol.2015.03.015  1
2015 Chen YH, Huang EY, Kuo TT, Ma HI, Hoffer BJ, Tsui PF, Tsai JJ, Chou YC, Chiang YH. Dopamine Release Impairment in Striatum After Different Levels of Cerebral Cortical Fluid Percussion Injury. Cell Transplantation. 24: 2113-28. PMID 25198499 DOI: 10.3727/096368914X683584  0.4
2015 Luo Y, Hoffer A, Hoffer B, Qi X. Mitochondria: A therapeutic target for Parkinson’s disease? International Journal of Molecular Sciences. 16: 20704-20730. DOI: 10.3390/ijms160920704  1
2014 Ross JM, Coppotelli G, Hoffer BJ, Olson L. Maternally transmitted mitochondrial DNA mutations can reduce lifespan. Scientific Reports. 4: 6569. PMID 25299268 DOI: 10.1038/srep06569  0.76
2014 Eakin K, Baratz-Goldstein R, Pick CG, Zindel O, Balaban CD, Hoffer ME, Lockwood M, Miller J, Hoffer BJ. Efficacy of N-acetyl cysteine in traumatic brain injury. Plos One. 9: e90617. PMID 24740427 DOI: 10.1371/journal.pone.0090617  1
2014 Greig NH, Tweedie D, Rachmany L, Li Y, Rubovitch V, Schreiber S, Chiang YH, Hoffer BJ, Miller J, Lahiri DK, Sambamurti K, Becker RE, Pick CG. Incretin mimetics as pharmacologic tools to elucidate and as a new drug strategy to treat traumatic brain injury. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: S62-75. PMID 24529527 DOI: 10.1016/j.jalz.2013.12.011  1
2013 Eakin K, Li Y, Chiang YH, Hoffer BJ, Rosenheim H, Greig NH, Miller JP. Exendin-4 ameliorates traumatic brain injury-induced cognitive impairment in rats. Plos One. 8: e82016. PMID 24312624 DOI: 10.1371/journal.pone.0082016  1
2013 Ross JM, Stewart JB, Hagström E, Brené S, Mourier A, Coppotelli G, Freyer C, Lagouge M, Hoffer BJ, Olson L, Larsson NG. Germline mitochondrial DNA mutations aggravate ageing and can impair brain development. Nature. 501: 412-5. PMID 23965628 DOI: 10.1038/nature12474  1
2013 Woods AS, Colsch B, Jackson SN, Post J, Baldwin K, Roux A, Hoffer B, Cox BM, Hoffer M, Rubovitch V, Pick CG, Schultz JA, Balaban C. Gangliosides and ceramides change in a mouse model of blast induced traumatic brain injury. Acs Chemical Neuroscience. 4: 594-600. PMID 23590251 DOI: 10.1021/cn300216h  1
2013 Tweedie D, Rachmany L, Rubovitch V, Zhang Y, Becker KG, Perez E, Hoffer BJ, Pick CG, Greig NH. Changes in mouse cognition and hippocampal gene expression observed in a mild physical- and blast-traumatic brain injury. Neurobiology of Disease. 54: 1-11. PMID 23454194 DOI: 10.1016/j.nbd.2013.02.006  1
2013 Hoffer ME, Balaban C, Slade MD, Tsao JW, Hoffer B. Amelioration of acute sequelae of blast induced mild traumatic brain injury by N-acetyl cysteine: a double-blind, placebo controlled study. Plos One. 8: e54163. PMID 23372680 DOI: 10.1371/journal.pone.0054163  1
2013 Luo Y, Shen H, Liu HS, Yu SJ, Reiner DJ, Harvey BK, Hoffer BJ, Yang Y, Wang Y. CART peptide induces neuroregeneration in stroke rats. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 300-10. PMID 23211962 DOI: 10.1038/jcbfm.2012.172  1
2013 Eakin K, Hoffer B, Miller J. Substantia nigra vulnerability after a single moderate diffuse brain injury in the rat. Experimental Neurology. 240: 103-7. PMID 23153576 DOI: 10.1016/j.expneurol.2012.11.005  1
2013 Tweedie D, Rachmany L, Rubovitch V, Lehrmann E, Zhang Y, Becker KG, Perez E, Miller J, Hoffer BJ, Greig NH, Pick CG. Exendin-4, a glucagon-like peptide-1 receptor agonist prevents mTBI-induced changes in hippocampus gene expression and memory deficits in mice. Experimental Neurology. 239: 170-82. PMID 23059457 DOI: 10.1016/j.expneurol.2012.10.001  1
2013 Sterky FH, Pernold K, Harvey BK, Lindqvist E, Hoffer BJ, Olson L. Glial cell line-derived neurotrophic factor partially ameliorates motor symptoms without slowing neurodegeneration in mice with respiratory chain-deficient dopamine neurons. Cell Transplantation. 22: 1529-39. PMID 23051605 DOI: 10.3727/096368912X657693  1
2013 Rachmany L, Tweedie D, Li Y, Rubovitch V, Holloway HW, Miller J, Hoffer BJ, Greig NH, Pick CG. Exendin-4 induced glucagon-like peptide-1 receptor activation reverses behavioral impairments of mild traumatic brain injury in mice. Age (Dordrecht, Netherlands). 35: 1621-36. PMID 22892942 DOI: 10.1007/s11357-012-9464-0  1
2012 Zhang Y, Granholm AC, Huh K, Shan L, Diaz-Ruiz O, Malik N, Olson L, Hoffer BJ, Lupica CR, Hoffman AF, Bäckman CM. PTEN deletion enhances survival, neurite outgrowth and function of dopamine neuron grafts to MitoPark mice. Brain : a Journal of Neurology. 135: 2736-49. PMID 22961549 DOI: 10.1093/brain/aws196  1
2012 Zigmond MJ, Cameron JL, Hoffer BJ, Smeyne RJ. Neurorestoration by physical exercise: moving forward. Parkinsonism & Related Disorders. 18: S147-50. PMID 22166417 DOI: 10.1016/S1353-8020(11)70046-3  1
2012 Chen MF, Huang YC, Long C, Yang HI, Lee HC, Chen PY, Hoffer BJ, Lee TJ. Bimodal effects of fluoxetine on cerebral nitrergic neurogenic vasodilation in porcine large cerebral arteries. Neuropharmacology. 62: 1651-8. PMID 22155207 DOI: 10.1016/j.neuropharm.2011.11.011  1
2012 Airavaara M, Harvey BK, Voutilainen MH, Shen H, Chou J, Lindholm P, Lindahl M, Tuominen RK, Saarma M, Hoffer B, Wang Y. CDNF protects the nigrostriatal dopamine system and promotes recovery after MPTP treatment in mice. Cell Transplantation. 21: 1213-23. PMID 21943517 DOI: 10.3727/096368911X600948  1
2012 Tsai MJ, Shyue SK, Liou DY, Yang TH, Weng CF, Huang MC, Lin YL, Kuo HS, Lee MJ, Huang SL, Huang WC, Hoffer BJ, Cheng H. Protective effect of BMP-7 Overexpression via adenovirus-mediated transfer on spinal cord injury in culture and in vivo Handbook On Oxidative Stress New Research. 415-429.  1
2011 Rubovitch V, Ten-Bosch M, Zohar O, Harrison CR, Tempel-Brami C, Stein E, Hoffer BJ, Balaban CD, Schreiber S, Chiu WT, Pick CG. A mouse model of blast-induced mild traumatic brain injury. Experimental Neurology. 232: 280-9. PMID 21946269 DOI: 10.1016/j.expneurol.2011.09.018  1
2011 Hoffer BJ, Harvey BK. Is GDNF beneficial in Parkinson disease? Nature Reviews. Neurology. 7: 600-2. PMID 21931353 DOI: 10.1038/nrneurol.2011.149  1
2011 Harvey BK, Airavaara M, Hinzman J, Wires EM, Chiocco MJ, Howard DB, Shen H, Gerhardt G, Hoffer BJ, Wang Y. Targeted over-expression of glutamate transporter 1 (GLT-1) reduces ischemic brain injury in a rat model of stroke. Plos One. 6: e22135. PMID 21853027 DOI: 10.1371/journal.pone.0022135  1
2011 Baratz R, Tweedie D, Rubovitch V, Luo W, Yoon JS, Hoffer BJ, Greig NH, Pick CG. Tumor necrosis factor-α synthesis inhibitor, 3,6'-dithiothalidomide, reverses behavioral impairments induced by minimal traumatic brain injury in mice. Journal of Neurochemistry. 118: 1032-42. PMID 21740439 DOI: 10.1111/j.1471-4159.2011.07377.x  1
2011 Hoffer BJ. Commentary on chronic infusion of CDNF prevents 6-OHDA-induced deficits in a rat model of Parkinson's disease. Merja H. Voutilainen et al. Experimental Neurology. 230: 162-6. PMID 21554875 DOI: 10.1016/j.expneurol.2011.04.015  1
2011 Chou J, Greig NH, Reiner D, Hoffer BJ, Wang Y. Enhanced survival of dopaminergic neuronal transplants in hemiparkinsonian rats by the p53 inactivator PFT-α. Cell Transplantation. 20: 1351-9. PMID 21294958 DOI: 10.3727/096368910X557173  1
2011 Good CH, Hoffman AF, Hoffer BJ, Chefer VI, Shippenberg TS, Bäckman CM, Larsson NG, Olson L, Gellhaar S, Galter D, Lupica CR. Impaired nigrostriatal function precedes behavioral deficits in a genetic mitochondrial model of Parkinson's disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 1333-44. PMID 21233488 DOI: 10.1096/fj.10-173625  1
2011 Airavaara M, Pickens CL, Stern AL, Wihbey KA, Harvey BK, Bossert JM, Liu QR, Hoffer BJ, Shaham Y. Endogenous GDNF in ventral tegmental area and nucleus accumbens does not play a role in the incubation of heroin craving. Addiction Biology. 16: 261-72. PMID 21182575 DOI: 10.1111/j.1369-1600.2010.00281.x  1
2011 Harvey BK, Richie CT, Hoffer BJ, Airavaara M. Transgenic animal models of neurodegeneration based on human genetic studies. Journal of Neural Transmission (Vienna, Austria : 1996). 118: 27-45. PMID 20931247 DOI: 10.1007/s00702-010-0476-6  1
2010 Luo Y, Wang Y, Kuang SY, Chiang YH, Hoffer B. Decreased level of Nurr1 in heterozygous young adult mice leads to exacerbated acute and long-term toxicity after repeated methamphetamine exposure Plos One. 5. PMID 21151937 DOI: 10.1371/journal.pone.0015193  1
2010 Ross JM, Öberg J, Brené S, Coppotelli G, Terzioglu M, Pernold K, Goiny M, Sitnikov R, Kehr J, Trifunovic A, Larsson NG, Hoffer BJ, Olson L. High brain lactate is a hallmark of aging and caused by a shift in the lactate dehydrogenase A/B ratio. Proceedings of the National Academy of Sciences of the United States of America. 107: 20087-92. PMID 21041631 DOI: 10.1073/pnas.1008189107  1
2010 Airavaara M, Chiocco MJ, Howard DB, Zuchowski KL, Peränen J, Liu C, Fang S, Hoffer BJ, Wang Y, Harvey BK. Widespread cortical expression of MANF by AAV serotype 7: localization and protection against ischemic brain injury. Experimental Neurology. 225: 104-13. PMID 20685313 DOI: 10.1016/j.expneurol.2010.05.020  1
2010 Tsai MJ, Pan HA, Liou DY, Weng CF, Hoffer BJ, Cheng H. Adenoviral gene transfer of bone morphogenetic protein-7 enhances functional recovery after sciatic nerve injury in rats. Gene Therapy. 17: 1214-24. PMID 20520648 DOI: 10.1038/gt.2010.72  1
2010 Galter D, Pernold K, Yoshitake T, Lindqvist E, Hoffer B, Kehr J, Larsson NG, Olson L. MitoPark mice mirror the slow progression of key symptoms and L-DOPA response in Parkinson's disease. Genes, Brain, and Behavior. 9: 173-81. PMID 20002202 DOI: 10.1111/j.1601-183X.2009.00542.x  1
2010 Westerlund M, Hoffer B, Olson L. Parkinson's disease: Exit toxins, enter genetics. Progress in Neurobiology. 90: 146-56. PMID 19925845 DOI: 10.1016/j.pneurobio.2009.11.001  1
2009 Luo Y, Kuang SY, Hoffer B. How useful are stem cells in PD therapy? Parkinsonism and Related Disorders. 15: S171-S175. PMID 20082984 DOI: 10.1016/S1353-8020(09)70808-9  1
2009 Tsai SY, Hayashi T, Harvey BK, Wang Y, Wu WW, Shen RF, Zhang Y, Becker KG, Hoffer BJ, Su TP. Sigma-1 receptors regulate hippocampal dendritic spine formation via a free radical-sensitive mechanism involving Rac1xGTP pathway. Proceedings of the National Academy of Sciences of the United States of America. 106: 22468-73. PMID 20018732 DOI: 10.1073/pnas.0909089106  1
2009 Karlén A, Karlsson TE, Mattsson A, Lundströmer K, Codeluppi S, Pham TM, Bäckman CM, Ogren SO, Aberg E, Hoffman AF, Sherling MA, Lupica CR, Hoffer BJ, Spenger C, Josephson A, et al. Nogo receptor 1 regulates formation of lasting memories. Proceedings of the National Academy of Sciences of the United States of America. 106: 20476-81. PMID 19915139 DOI: 10.1073/pnas.0905390106  1
2009 Luo Y, Sarabi SA, Backman C, Shan L, Hoffer B, Federoff H. Expression pattern of NuIP gene in adult mouse brain. Brain Research. 1302: 42-53. PMID 19765553 DOI: 10.1016/j.brainres.2009.09.026  1
2009 Luo Y, Kuo CC, Shen H, Chou J, Greig NH, Hoffer BJ, Wang Y. Delayed treatment with a p53 inhibitor enhances recovery in stroke brain. Annals of Neurology. 65: 520-30. PMID 19475672 DOI: 10.1002/ana.21592  1
2009 Harvey BK, Chou J, Shen H, Hoffer BJ, Wang Y. Diadenosine tetraphosphate reduces toxicity caused by high-dose methamphetamine administration. Neurotoxicology. 30: 436-44. PMID 19442829 DOI: 10.1016/j.neuro.2009.02.003  1
2009 Airavaara M, Shen H, Kuo CC, Peränen J, Saarma M, Hoffer B, Wang Y. Mesencephalic astrocyte-derived neurotrophic factor reduces ischemic brain injury and promotes behavioral recovery in rats Journal of Comparative Neurology. 515: 116-124. PMID 19399876 DOI: 10.1002/cne.22039  1
2009 Lu L, Wang X, Wu P, Xu C, Zhao M, Morales M, Harvey BK, Hoffer BJ, Shaham Y. Role of ventral tegmental area glial cell line-derived neurotrophic factor in incubation of cocaine craving. Biological Psychiatry. 66: 137-45. PMID 19345340 DOI: 10.1016/j.biopsych.2009.02.009  1
2009 Israelsson C, Wang Y, Kylberg A, Pick CG, Hoffer BJ, Ebendal T. Closed head injury in a mouse model results in molecular changes indicating inflammatory responses. Journal of Neurotrauma. 26: 1307-14. PMID 19317611 DOI: 10.1089/neu.2008-0676  1
2009 Shen H, Kuo CC, Chou J, Delvolve A, Jackson SN, Post J, Woods AS, Hoffer BJ, Wang Y, Harvey BK. Astaxanthin reduces ischemic brain injury in adult rats. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 1958-68. PMID 19218497 DOI: 10.1096/fj.08-123281  1
2009 Li Y, Perry T, Kindy MS, Harvey BK, Tweedie D, Holloway HW, Powers K, Shen H, Egan JM, Sambamurti K, Brossi A, Lahiri DK, Mattson MP, Hoffer BJ, Wang Y, et al. GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism. Proceedings of the National Academy of Sciences of the United States of America. 106: 1285-90. PMID 19164583 DOI: 10.1073/pnas.0806720106  1
2009 Shen H, Luo Y, Kuo CC, Deng X, Chang CF, Harvey BK, Hoffer BJ, Wang Y. 9-Cis-retinoic acid reduces ischemic brain injury in rodents via bone morphogenetic protein. Journal of Neuroscience Research. 87: 545-55. PMID 18803283 DOI: 10.1002/jnr.21865  1
2009 Bäckman CM, Zhang Y, Malik N, Shan L, Hoffer BJ, Westphal H, Tomac AC. Generalized tetracycline induced Cre recombinase expression through the ROSA26 locus of recombinant mice. Journal of Neuroscience Methods. 176: 16-23. PMID 18801387 DOI: 10.1016/j.jneumeth.2008.08.024  1
2009 Shen H, Hoffer BJ, Wang Y. Restoration of Nigrostriatal Pathway in Parkinson's Animals by the Bridge Transplantation Technique Journal of Experimental and Clinical Medicine. 1: 12-16. DOI: 10.1016/S1878-3317(09)60005-X  1
2008 Zaman V, Boger HA, Granholm AC, Rohrer B, Moore A, Buhusi M, Gerhardt GA, Hoffer BJ, Middaugh LD. The nigrostriatal dopamine system of aging GFRalpha-1 heterozygous mice: neurochemistry, morphology and behavior. The European Journal of Neuroscience. 28: 1557-68. PMID 18973577 DOI: 10.1111/j.1460-9568.2008.06456.x  1
2008 Boger HA, Middaugh LD, Zaman V, Hoffer B, Granholm AC. Differential effects of the dopamine neurotoxin MPTP in animals with a partial deletion of the GDNF receptor, GFR alpha1, gene. Brain Research. 1241: 18-28. PMID 18822276 DOI: 10.1016/j.brainres.2008.09.011  1
2008 Chou J, Harvey BK, Ebendal T, Hoffer B, Wang Y. Nigrostriatal alterations in bone morphogenetic protein receptor II dominant negative mice. Acta Neurochirurgica. Supplement. 101: 93-8. PMID 18642641 DOI: 10.1007/978-3-211-78205-7-16  1
2008 Harvey BK, Wang Y, Hoffer BJ. Transgenic rodent models of Parkinson's disease. Acta Neurochirurgica. Supplement. 101: 89-92. PMID 18642640 DOI: 10.1007/978-3-211-78205-7-15  1
2008 Sarabi AS, Shen H, Wang Y, Hoffer BJ, Bäckman CM. Gene expression patterns in mouse cortical penumbra after focal ischemic brain injury and reperfusion. Journal of Neuroscience Research. 86: 2912-24. PMID 18506852 DOI: 10.1002/jnr.21734  1
2008 Chou J, Luo Y, Kuo CC, Powers K, Shen H, Harvey BK, Hoffer BJ, Wang Y. Bone morphogenetic protein-7 reduces toxicity induced by high doses of methamphetamine in rodents. Neuroscience. 151: 92-103. PMID 18082966 DOI: 10.1016/j.neuroscience.2007.10.044  1
2007 Chiocco MJ, Harvey BK, Wang Y, Hoffer BJ. Neurotrophic factors for the treatment of Parkinson's disease. Parkinsonism & Related Disorders. 13: S321-8. PMID 18267258 DOI: 10.1016/S1353-8020(08)70024-5  1
2007 Harvey BK, Chen GJ, Schoen CJ, Lee CT, Howard DB, Dillon-Carter O, Coggiano M, Freed WJ, Wang Y, Hoffer BJ, Sanchez JF. An immortalized rat ventral mesencephalic cell line, RTC4, is protective in a rodent model of stroke. Cell Transplantation. 16: 483-91. PMID 17708338  1
2007 Tsai MJ, Weng CF, Shyue SK, Liou DY, Chen CH, Chiu CW, Yang TH, Pan HA, Liao RI, Kuo HS, Huang MC, Huang WC, Hoffer BJ, Cheng H. Dual effect of adenovirus-mediated transfer of BMP7 in mixed neuron-glial cultures: neuroprotection and cellular differentiation. Journal of Neuroscience Research. 85: 2950-9. PMID 17628501 DOI: 10.1002/jnr.21395  1
2007 Tweedie D, Milman A, Holloway HW, Li Y, Harvey BK, Shen H, Pistell PJ, Lahiri DK, Hoffer BJ, Wang Y, Pick CG, Greig NH. Apoptotic and behavioral sequelae of mild brain trauma in mice. Journal of Neuroscience Research. 85: 805-15. PMID 17243171 DOI: 10.1002/jnr.21160  1
2007 Ekstrand MI, Terzioglu M, Galter D, Zhu S, Hofstetter C, Lindqvist E, Thams S, Bergstrand A, Hansson FS, Trifunovic A, Hoffer B, Cullheim S, Mohammed AH, Olson L, Larsson NG. Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neurons. Proceedings of the National Academy of Sciences of the United States of America. 104: 1325-30. PMID 17227870 DOI: 10.1073/pnas.0605208103  1
2007 Bäckman CM, Shan L, Zhang Y, Hoffer BJ, Tomac AC. Alterations in prodynorphin, proenkephalin, and GAD67 mRNA levels in the aged human putamen: correlation with Parkinson's disease. Journal of Neuroscience Research. 85: 798-804. PMID 17203488 DOI: 10.1002/jnr.21164  1
2007 af Bjerkén S, Boger HA, Nelson M, Hoffer BJ, Granholm AC, Strömberg I. Effects of glial cell line-derived neurotrophic factor deletion on ventral mesencephalic organotypic tissue cultures. Brain Research. 1133: 10-9. PMID 17184739 DOI: 10.1016/j.brainres.2006.11.052  1
2006 Boger HA, Middaugh LD, Huang P, Zaman V, Smith AC, Hoffer BJ, Tomac AC, Granholm AC. A partial GDNF depletion leads to earlier age-related deterioration of motor function and tyrosine hydroxylase expression in the substantia nigra. Experimental Neurology. 202: 336-47. PMID 16889771 DOI: 10.1016/j.expneurol.2006.06.006  1
2006 Bäckman CM, Malik N, Zhang Y, Shan L, Grinberg A, Hoffer BJ, Westphal H, Tomac AC. Characterization of a mouse strain expressing Cre recombinase from the 3' untranslated region of the dopamine transporter locus. Genesis (New York, N.Y. : 2000). 44: 383-90. PMID 16865686 DOI: 10.1002/dvg.20228  1
2006 Long C, Chen MF, Sarwinski SJ, Chen PY, Si M, Hoffer BJ, Evans MS, Lee TJ. Monoamine uptake inhibitors block alpha7-nAChR-mediated cerebral nitrergic neurogenic vasodilation. American Journal of Physiology. Heart and Circulatory Physiology. 291: H202-9. PMID 16772524 DOI: 10.1152/ajpheart.01192.2005  1
2006 Bäckman CM, Shan L, Zhang YJ, Hoffer BJ, Leonard S, Troncoso JC, Vonsatel P, Tomac AC. Gene expression patterns for GDNF and its receptors in the human putamen affected by Parkinson's disease: a real-time PCR study. Molecular and Cellular Endocrinology. 252: 160-6. PMID 16644101 DOI: 10.1016/j.mce.2006.03.013  1
2005 Chiang YH, Borlongan CV, Zhou FC, Hoffer BJ, Wang Y. Transplantation of fetal kidney cells: neuroprotection and neuroregeneration. Cell Transplantation. 14: 1-9. PMID 15789657  1
2005 Harvey BK, Hoffer BJ, Wang Y. Stroke and TGF-beta proteins: glial cell line-derived neurotrophic factor and bone morphogenetic protein. Pharmacology & Therapeutics. 105: 113-25. PMID 15670622 DOI: 10.1016/j.pharmthera.2004.09.003  1
2004 Bäckman CM, Zhang Y, Hoffer BJ, Tomac AC. Tetracycline-inducible expression systems for the generation of transgenic animals: a comparison of various inducible systems carried in a single vector. Journal of Neuroscience Methods. 139: 257-62. PMID 15488239 DOI: 10.1016/j.jneumeth.2004.05.012  1
2004 Harvey BK, Mark A, Chou J, Chen GJ, Hoffer BJ, Wang Y. Neurotrophic effects of bone morphogenetic protein-7 in a rat model of Parkinson's disease. Brain Research. 1022: 88-95. PMID 15353217 DOI: 10.1016/j.brainres.2004.06.072  1
2004 Quintero EM, Willis LM, Zaman V, Lee J, Boger HA, Tomac A, Hoffer BJ, Strömberg I, Granholm AC. Glial cell line-derived neurotrophic factor is essential for neuronal survival in the locus coeruleus-hippocampal noradrenergic pathway. Neuroscience. 124: 137-46. PMID 14960346 DOI: 10.1016/j.neuroscience.2003.11.001  1
2003 Zaman V, Li Z, Middaugh L, Ramamoorthy S, Rohrer B, Nelson ME, Tomac AC, Hoffer BJ, Gerhardt GA, Granholm AC. The Noradrenergic System of Aged GDNF Heterozygous Mice. Cell Transplantation. 12: 291-303. PMID 28853928 DOI: 10.3727/000000003108746740  0.84
2003 Bäckman C, Zhang Y, Hoffer BJ, Tomac AC. Short interfering RNAs (siRNAs) for reducing dopaminergic phenotypic markers. Journal of Neuroscience Methods. 131: 51-6. PMID 14659823 DOI: 10.1016/S0165-0270(03)00236-X  1
2003 Chen HL, Lein PJ, Wang JY, Gash D, Hoffer BJ, Chiang YH. Expression of bone morphogenetic proteins in the brain during normal aging and in 6-hydroxydopamine-lesioned animals. Brain Research. 994: 81-90. PMID 14642451 DOI: 10.1016/j.brainres.2003.09.020  1
2003 Harvey BK, Chang CF, Chiang YH, Bowers WJ, Morales M, Hoffer BJ, Wang Y, Federoff HJ. HSV amplicon delivery of glial cell line-derived neurotrophic factor is neuroprotective against ischemic injury. Experimental Neurology. 183: 47-55. PMID 12957487 DOI: 10.1016/S0014-4886(03)00080-3  1
2003 Bäckman C, You ZB, Perlmann T, Hoffer BJ. Elevated locomotor activity without altered striatal dopamine contents in Nurr1 heterozygous mice after acute exposure to methamphetamine. Behavioural Brain Research. 143: 95-100. PMID 12842300 DOI: 10.1016/S0166-4328(03)00029-9  1
2003 Zaman V, Li Z, Middaugh L, Ramamoorthy S, Rohrer B, Nelson ME, Tomac AC, Hoffer BJ, Gerhardt GA, Granholm ACh. The noradrenergic system of aged GDNF heterozygous mice. Cell Transplantation. 12: 291-303. PMID 12797383  1
2003 Sarabi A, Chang CF, Wang Y, Tomac AC, Hoffer BJ, Morales M. Differential expression of the cell line-derived neurotrophic factor (GDNF) receptor GFRalpha1 in heterozygous Gfralpha1 null-mutant mice after stroke. Neuroscience Letters. 341: 241-5. PMID 12697293 DOI: 10.1016/S0304-3940(03)00195-2  1
2003 Chang CF, Lin SZ, Chiang YH, Morales M, Chou J, Lein P, Chen HL, Hoffer BJ, Wang Y. Intravenous administration of bone morphogenetic protein-7 after ischemia improves motor function in stroke rats. Stroke; a Journal of Cerebral Circulation. 34: 558-64. PMID 12574575 DOI: 10.1161/01.STR.0000051507.64423.00  1
2003 Sarabi A, Hoffer BJ, Olson L, Morales M. Glial cell line neurotrophic factor-family receptor alpha-1 is present in central neurons with distinct phenotypes. Neuroscience. 116: 261-73. PMID 12535958 DOI: 10.1016/S0306-4522(02)00559-6  1
2002 Borlongan CV, Emerich DF, Hoffer BJ, Bartus RT. Bradykinin receptor agonist facilitates low-dose cyclosporine-A protection against 6-hydroxydopamine neurotoxicity. Brain Research. 956: 211-20. PMID 12445688 DOI: 10.1016/S0006-8993(02)03474-1  1
2002 Chang CF, Morales M, Chou J, Chen HL, Hoffer B, Wang Y. Bone morphogenetic proteins are involved in fetal kidney tissue transplantation-induced neuroprotection in stroke rats Neuropharmacology. 43: 418-426. PMID 12243771 DOI: 10.1016/S0028-3908(02)00092-8  1
2002 Tomac AC, Agulnick AD, Haughey N, Chang CF, Zhang Y, Bäckman C, Morales M, Mattson MP, Wang Y, Westphal H, Hoffer BJ. Effects of cerebral ischemia in mice deficient in Persephin. Proceedings of the National Academy of Sciences of the United States of America. 99: 9521-6. PMID 12093930 DOI: 10.1073/pnas.152535899  1
2002 McGrath J, Lintz E, Hoffer BJ, Gerhardt GA, Quintero EM, Granholm AC. Adeno-associated viral delivery of GDNF promotes recovery of dopaminergic phenotype following a unilateral 6-hydroxydopamine lesion. Cell Transplantation. 11: 215-27. PMID 12075987  1
2001 Tomac AC, Hoffer BJ. Assignment of the mouse Park2 (PARKIN), the homologue to a new human Parkinson candidate gene, to the telomeric region of mouse 17A3.2-3.3, by in situ hybridization. Cytogenetics and Cell Genetics. 95: 120-1. PMID 11978985  1
2001 Sarabi A, Hoffer BJ, Olson L, Morales M. GFRalpha-1 mRNA in dopaminergic and nondopaminergic neurons in the substantia nigra and ventral tegmental area. The Journal of Comparative Neurology. 441: 106-17. PMID 11745638 DOI: 10.1002/cne.1400  1
2001 Croll RP. Catecholamine-containing cells in the central nervous system and periphery of Aplysia californica. The Journal of Comparative Neurology. 441: 91-105. PMID 11745637 DOI: 10.1002/cne.1399  1
2001 Wang Y, Chang CF, Morales M, Chou J, Chen HL, Chiang YH, Lin SZ, Cadet JL, Deng X, Wang JY, Chen SY, Kaplan PL, Hoffer BJ. Bone morphogenetic protein-6 reduces ischemia-induced brain damage in rats. Stroke; a Journal of Cerebral Circulation. 32: 2170-8. PMID 11546913  1
2001 Chen MT, Morales M, Woodward DJ, Hoffer BJ, Janak PH. In vivo extracellular recording of striatal neurons in the awake rat following unilateral 6-hydroxydopamine lesions. Experimental Neurology. 171: 72-83. PMID 11520122 DOI: 10.1006/exnr.2001.7730  1
2001 Wang JY, Wu JN, Cherng TL, Hoffer BJ, Chen HH, Borlongan CV, Wang Y. Vitamin D(3) attenuates 6-hydroxydopamine-induced neurotoxicity in rats. Brain Research. 904: 67-75. PMID 11516412 DOI: 10.1016/S0006-8993(01)02450-7  1
2001 Borlongan CV, Zhou FC, Hayashi T, Su TP, Hoffer BJ, Wang Y. Involvement of GDNF in neuronal protection against 6-OHDA-induced parkinsonism following intracerebral transplantation of fetal kidney tissues in adult rats. Neurobiology of Disease. 8: 636-46. PMID 11493028 DOI: 10.1006/nbdi.2001.0410  1
2001 Sarabi A, Chang CF, Wang Y, Hoffer BJ, Morales M. Time course study of GFRalpha-1 expression in an animal model of stroke. Experimental Neurology. 170: 283-9. PMID 11476594 DOI: 10.1006/exnr.2001.7714  1
2001 Bäckman C, Hoffer BJ, Misawa H, Morales M. Cellular mRNA expression of the transcription factor NGFI-B suggests a gene regulatory role in striatal opiate-peptide neurons. Brain Research. 903: 26-32. PMID 11382384 DOI: 10.1016/S0006-8993(01)02332-0  1
2001 Tzeng SF, Cheng H, Lee YS, Wu JP, Hoffer BJ, Kuo JS. Expression of neural cell adhesion molecule in spinal cords following a complete transection. Life Sciences. 68: 1005-12. PMID 11212863 DOI: 10.1016/S0024-3205(00)01003-1  1
2001 Chiang Y, Morales M, Zhou FC, Borlongan C, Hoffer BJ, Wang Y. Fetal intra-nigral ventral mesencephalon and kidney tissue bridge transplantation restores the nigrostriatal dopamine pathway in hemi-parkinsonian rats. Brain Research. 889: 200-7. PMID 11166704 DOI: 10.1016/S0006-8993(00)03133-4  1
2000 Jeng CH, Chou JR, Hoffer BJ, Wang Y. Serotonergic modulation of ethanol-induced electrophysiological depression in young and aged rats. Alcoholism, Clinical and Experimental Research. 24: 1730-41. PMID 11104121  1
2000 Chang CF, Niu KC, Hoffer BJ, Wang Y, Borlongan CV. Hyperbaric oxygen therapy for treatment of postischemic stroke in adult rats. Experimental Neurology. 166: 298-306. PMID 11085895 DOI: 10.1006/exnr.2000.7506  1
2000 Sarabi A, Hoffer BJ, Olson L, Morales M. GFR alpha-1 is expressed in parvalbumin GABAergic neurons in the hippocampus. Brain Research. 877: 262-70. PMID 10986340 DOI: 10.1016/S0006-8993(00)02682-2  1
2000 Granholm AC, Reyland M, Albeck D, Sanders L, Gerhardt G, Hoernig G, Shen L, Westphal H, Hoffer B. Glial cell line-derived neurotrophic factor is essential for postnatal survival of midbrain dopamine neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 3182-90. PMID 10777782  1
2000 Wang Y, Chiang YH, Su TP, Hayashi T, Morales M, Hoffer BJ, Lin SZ. Vitamin D(3) attenuates cortical infarction induced by middle cerebral arterial ligation in rats. Neuropharmacology. 39: 873-80. PMID 10699453 DOI: 10.1016/S0028-3908(99)00255-5  1
2000 Tomac AC, Grinberg A, Huang SP, Nosrat C, Wang Y, Borlongan C, Lin SZ, Chiang YH, Olson L, Westphal H, Hoffer BJ. Glial cell line-derived neurotrophic factor receptor alpha1 availability regulates glial cell line-derived neurotrophic factor signaling: evidence from mice carrying one or two mutated alleles. Neuroscience. 95: 1011-23. PMID 10682708 DOI: 10.1016/S0306-4522(99)00503-5  1
1999 Bäckman C, Perlmann T, Wallén A, Hoffer BJ, Morales M. A selective group of dopaminergic neurons express Nurr1 in the adult mouse brain. Brain Research. 851: 125-32. PMID 10642835 DOI: 10.1016/S0006-8993(99)02149-6  1
1999 Chiang YH, Lin SZ, Borlongan CV, Hoffer BJ, Morales M, Wang Y. Transplantation of fetal kidney tissue reduces cerebral infarction induced by middle cerebral artery ligation. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 19: 1329-35. PMID 10598937 DOI: 10.1097/00004647-199912000-00006  1
1999 Granholm AC, Sanders LA, Ickes B, Albeck D, Hoffer BJ, Young DA, Kaplan PL. Effects of osteogenic protein-1 (OP-1) treatment on fetal spinal cord transplants to the anterior chamber of the eye. Cell Transplantation. 8: 75-85. PMID 10338277  1
1999 Lin SZ, Hoffer BJ, Kaplan P, Wang Y. Osteogenic protein-1 protects against cerebral infarction induced by MCA ligation in adult rats. Stroke; a Journal of Cerebral Circulation. 30: 126-33. PMID 9880400  1
1998 Kobayashi S, Ogren SO, Hoffer BJ, Olson L. Dopamine D1 and D2 receptor-mediated acute and long-lasting behavioral effects of glial cell line-derived neurotrophic factor administered into the striatum. Experimental Neurology. 154: 302-14. PMID 9878169 DOI: 10.1006/exnr.1998.6952  1
1998 David DJ, Zahniser NR, Hoffer BJ, Gerhardt GA. In vivo electrochemical studies of dopamine clearance in subregions of rat nucleus accumbens: differential properties of the core and shell. Experimental Neurology. 153: 277-86. PMID 9784287 DOI: 10.1006/exnr.1998.6898  0.84
1998 Olson L, Cheng H, Zetterström RH, Solomin L, Jansson L, Giménez-Llort L, Hoffer BJ, Perlmann T. On CNS repair and protection strategies: novel approaches with implications for spinal cord injury and Parkinson's disease. Brain Research. Brain Research Reviews. 26: 302-5. PMID 9651546 DOI: 10.1016/S0165-0173(97)00051-9  1
1998 Tang FI, Tien LT, Zhou FC, Hoffer BJ, Wang Y. Intranigral ventral mesencephalic grafts and nigrostriatal injections of glial cell line-derived neurotrophic factor restore dopamine release in the striatum of 6-hydroxydopamine-lesioned rats. Experimental Brain Research. 119: 287-96. PMID 9551829 DOI: 10.1007/s002210050344  1
1998 Gash DM, Gerhardt GA, Hoffer BJ. Effects of glial cell line-derived neurotrophic factor on the nigrostriatal dopamine system in rodents and nonhuman primates. Advances in Pharmacology (San Diego, Calif.). 42: 911-5. PMID 9328046 DOI: 10.1016/S1054-3589(08)60895-9  1
1997 Bäckman C, Rose GM, Bartus RT, Hoffer BJ, Mufson EJ, Granholm AC. Carrier mediated delivery of NGF: alterations in basal forebrain neurons in aged rats revealed using antibodies against low and high affinity NGF receptors. The Journal of Comparative Neurology. 387: 1-11. PMID 9331167 DOI: 10.1002/(SICI)1096-9861(19971013)387:1<1::AID-CNE1>3.0.CO;2-5  1
1997 Shinoda M, Hoffer BJ, Olson L. Minor immunoreactivity in GDNF-, BDNF-, or NT-3-treated substantia nigra allografts. Journal of Neural Transplantation & Plasticity. 6: 83-96. PMID 9306240 DOI: 10.1155/NP.1997.83  1
1997 Granholm AC, Mott JL, Bowenkamp K, Eken S, Henry S, Hoffer BJ, Lapchak PA, Palmer MR, van Horne C, Gerhardt GA. Glial cell line-derived neurotrophic factor improves survival of ventral mesencephalic grafts to the 6-hydroxydopamine lesioned striatum. Experimental Brain Research. 116: 29-38. PMID 9305812 DOI: 10.1007/PL00005741  1
1997 Luthman J, Friedemann MN, Hoffer BJ, Gerhardt GA. In vivo electrochemical measurements of serotonin clearance in rat striatum: effects of neonatal 6-hydroxydopamine-induced serotonin hyperinnervation and serotonin uptake inhibitors. Journal of Neural Transmission (Vienna, Austria : 1996). 104: 379-97. PMID 9295172 DOI: 10.1007/BF01277658  1
1997 Hoffman AF, van Horne CG, Eken S, Hoffer BJ, Gerhardt GA. In vivo microdialysis studies on somatodendritic dopamine release in the rat substantia nigra: effects of unilateral 6-OHDA lesions and GDNF. Experimental Neurology. 147: 130-41. PMID 9294410 DOI: 10.1006/exnr.1997.6571  1
1997 Nosrat CA, Tomac A, Hoffer BJ, Olson L. Cellular and developmental patterns of expression of Ret and glial cell line-derived neurotrophic factor receptor alpha mRNAs. Experimental Brain Research. 115: 410-22. PMID 9262196 DOI: 10.1007/PL00005711  1
1997 Albeck DS, Hoffer BJ, Quissell D, Sanders LA, Zerbe G, Granholm AC. A non-invasive transport system for GDNF across the blood-brain barrier. Neuroreport. 8: 2293-8. PMID 9243628  1
1997 Bowenkamp KE, Lapchak PA, Hoffer BJ, Miller PJ, Bickford PC. Intracerebroventricular glial cell line-derived neurotrophic factor improves motor function and supports nigrostriatal dopamine neurons in bilaterally 6-hydroxydopamine lesioned rats. Experimental Neurology. 145: 104-17. PMID 9184114 DOI: 10.1006/exnr.1997.6436  1
1997 Wang Y, Lin SZ, Chiou AL, Williams LR, Hoffer BJ. Glial cell line-derived neurotrophic factor protects against ischemia-induced injury in the cerebral cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 4341-8. PMID 9151750  1
1997 Zetterström RH, Solomin L, Jansson L, Hoffer BJ, Olson L, Perlmann T. Dopamine neuron agenesis in Nurr1-deficient mice. Science (New York, N.Y.). 276: 248-50. PMID 9092472 DOI: 10.1126/science.276.5310.248  1
1997 Granholm AC, Srivastava N, Mott JL, Henry S, Henry M, Westphal H, Pichel JG, Shen L, Hoffer BJ. Morphological alterations in the peripheral and central nervous systems of mice lacking glial cell line-derived neurotrophic factor (GDNF): immunohistochemical studies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 1168-78. PMID 8994069  1
1997 Blake CI, Spitz E, Leehey M, Hoffer BJ, Boyson SJ. Platelet mitochondrial respiratory chain function in Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 12: 3-8. PMID 8990047 DOI: 10.1002/mds.870120103  1
1996 Pichel JG, Shen L, Sheng HZ, Granholm AC, Drago J, Grinberg A, Lee EJ, Huang SP, Saarma M, Hoffer BJ, Sariola H, Westphal H. GDNF is required for kidney development and enteric innervation. Cold Spring Harbor Symposia On Quantitative Biology. 61: 445-57. PMID 9246473  1
1996 Hebert MA, Van Horne CG, Hoffer BJ, Gerhardt GA. Functional effects of GDNF in normal rat striatum: presynaptic studies using in vivo electrochemistry and microdialysis. The Journal of Pharmacology and Experimental Therapeutics. 279: 1181-90. PMID 8968339  1
1996 Bowenkamp KE, David D, Lapchak PL, Henry MA, Granholm AC, Hoffer BJ, Mahalik TJ. 6-hydroxydopamine induces the loss of the dopaminergic phenotype in substantia nigra neurons of the rat. A possible mechanism for restoration of the nigrostriatal circuit mediated by glial cell line-derived neurotrophic factor. Experimental Brain Research. 111: 1-7. PMID 8891630  1
1996 Wang Y, Tien LT, Lapchak PA, Hoffer BJ. GDNF triggers fiber outgrowth of fetal ventral mesencephalic grafts from nigra to striatum in 6-OHDA-lesioned rats. Cell and Tissue Research. 286: 225-33. PMID 8854891 DOI: 10.1007/s004410050691  1
1996 Nosrat CA, Tomac A, Lindqvist E, Lindskog S, Humpel C, Strömberg I, Ebendal T, Hoffer BJ, Olson L. Cellular expression of GDNF mRNA suggests multiple functions inside and outside the nervous system. Cell and Tissue Research. 286: 191-207. PMID 8854888 DOI: 10.1007/s004410050688  1
1996 Bowenkamp KE, Lapchak PA, Hoffer BJ, Bickford PC. Glial cell line-derived neurotrophic factor reverses motor impairment in 16-17 month old rats. Neuroscience Letters. 211: 81-4. PMID 8830849 DOI: 10.1016/0304-3940(96)12729-4  1
1996 Shinoda M, Hoffer BJ, Olson L. Interactions of neurotrophic factors GDNF and NT-3, but not BDNF, with the immune system following fetal spinal cord transplantation. Brain Research. 722: 153-67. PMID 8813361 DOI: 10.1016/0006-8993(96)00208-9  1
1996 Price ML, Hoffer BJ, Granholm AC. Effects of GDNF on fetal septal forebrain transplants in oculo. Experimental Neurology. 141: 181-9. PMID 8812151 DOI: 10.1006/exnr.1996.0152  1
1996 Shinoda M, Hudson JL, Strömberg I, Hoffer BJ, Moorhead JW, Olson L. Microglial cell responses to fetal ventral mesencephalic tissue grafting and to active and adoptive immunizations. Experimental Neurology. 141: 173-80. PMID 8812150 DOI: 10.1006/exnr.1996.0151  1
1996 Bäckman C, Rose GM, Hoffer BJ, Henry MA, Bartus RT, Friden P, Granholm AC. Systemic administration of a nerve growth factor conjugate reverses age-related cognitive dysfunction and prevents cholinergic neuron atrophy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 5437-42. PMID 8757256  1
1996 Pichel JG, Shen L, Sheng HZ, Granholm AC, Drago J, Grinberg A, Lee EJ, Huang SP, Saarma M, Hoffer BJ, Sariola H, Westphal H. Defects in enteric innervation and kidney development in mice lacking GDNF. Nature. 382: 73-6. PMID 8657307 DOI: 10.1038/382073a0  1
1996 Gash DM, Zhang Z, Ovadia A, Cass WA, Yi A, Simmerman L, Russell D, Martin D, Lapchak PA, Collins F, Hoffer BJ, Gerhardt GA. Functional recovery in parkinsonian monkeys treated with GDNF. Nature. 380: 252-5. PMID 8637574 DOI: 10.1038/380252a0  1
1996 Gerhardt GA, Cass WA, Hudson J, Henson M, Zhang Z, Ovadia A, Hoffer BJ, Gash DM. In vivo electrochemical studies of dopamine overflow and clearance in the striatum of normal and MPTP-treated rhesus monkeys. Journal of Neurochemistry. 66: 579-88. PMID 8592127  1
1995 Gash DM, Zhang Z, Cass WA, Ovadia A, Simmerman L, Martin D, Russell D, Collins F, Hoffer BJ, Gerhardt GA. Morphological and functional effects of intranigrally administered GDNF in normal rhesus monkeys. The Journal of Comparative Neurology. 363: 345-58. PMID 8847404 DOI: 10.1002/cne.903630302  1
1995 Gerhardt GA, Cass WA, Henson M, Zhang Z, Ovadia A, Hoffer BJ, Gash DM. Age-related changes in potassium-evoked overflow of dopamine in the striatum of the rhesus monkey. Neurobiology of Aging. 16: 939-46. PMID 8622785 DOI: 10.1016/0197-4580(95)02013-6  1
1995 Tomac A, Lindqvist E, Lin LF, Ogren SO, Young D, Hoffer BJ, Olson L. Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo. Nature. 373: 335-9. PMID 7830766 DOI: 10.1038/373335a0  1
1995 Ebendal T, Tomac A, Hoffer BJ, Olson L. Glial cell line-derived neurotrophic factor stimulates fiber formation and survival in cultured neurons from peripheral autonomic ganglia. Journal of Neuroscience Research. 40: 276-84. PMID 7745621 DOI: 10.1002/jnr.490400217  1
1995 Bäckman C, Biddle PT, Ebendal T, Friden PM, Gerhardt GA, Henry MA, Mackerlova L, Söderström S, Strömberg I, Walus L. Effects of transferrin receptor antibody-NGF conjugate on young and aged septal transplants in oculo. Experimental Neurology. 132: 1-15. PMID 7720818 DOI: 10.1016/0014-4886(95)90037-3  1
1995 Hudson J, Granholm AC, Gerhardt GA, Henry MA, Hoffman A, Biddle P, Leela NS, Mackerlova L, Lile JD, Collins F. Glial cell line-derived neurotrophic factor augments midbrain dopaminergic circuits in vivo. Brain Research Bulletin. 36: 425-32. PMID 7712205 DOI: 10.1016/0361-9230(94)00224-O  1
1995 Hoffer BJ, van Horne C. Survival of dopaminergic neurons in fetal-tissue grafts. The New England Journal of Medicine. 332: 1163-4. PMID 7700292 DOI: 10.1056/NEJM199504273321710  1
1995 Tomac A, Widenfalk J, Lin LF, Kohno T, Ebendal T, Hoffer BJ, Olson L. Retrograde axonal transport of glial cell line-derived neurotrophic factor in the adult nigrostriatal system suggests a trophic role in the adult. Proceedings of the National Academy of Sciences of the United States of America. 92: 8274-8. PMID 7667281 DOI: 10.1073/pnas.92.18.8274  1
1995 Shinoda M, Hudson JL, Strömberg I, Hoffer BJ, Moorhead JW, Olson L. Allogeneic grafts of fetal dopamine neurons: immunological reactions following active and adoptive immunizations. Brain Research. 680: 180-95. PMID 7663976 DOI: 10.1016/0006-8993(95)00260-W  1
1995 Bowenkamp KE, Hoffman AF, Gerhardt GA, Henry MA, Biddle PT, Hoffer BJ, Granholm AC. Glial cell line-derived neurotrophic factor supports survival of injured midbrain dopaminergic neurons. The Journal of Comparative Neurology. 355: 479-89. PMID 7636027 DOI: 10.1002/cne.903550402  1
1994 Hudson JL, Hoffman A, Strömberg I, Hoffer BJ, Moorhead JW. Allogeneic grafts of fetal dopamine neurons: behavioral indices of immunological interactions. Neuroscience Letters. 171: 32-6. PMID 8084493 DOI: 10.1016/0304-3940(94)90597-5  1
1994 Lin AM, Freund RK, Hoffer BJ, Palmer MR. Ethanol-induced depressions of cerebellar Purkinje neurons are potentiated by beta-adrenergic mechanisms in rat brain. The Journal of Pharmacology and Experimental Therapeutics. 271: 1175-80. PMID 7996423  1
1994 Hudson JL, Bickford P, Johansson M, Hoffer BJ, Strömberg I. Target and neurotransmitter specificity of fetal central nervous system transplants: importance for functional reinnervation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 283-90. PMID 7904305  1
1994 Hoffer BJ, Hoffman A, Bowenkamp K, Huettl P, Hudson J, Martin D, Lin LF, Gerhardt GA. Glial cell line-derived neurotrophic factor reverses toxin-induced injury to midbrain dopaminergic neurons in vivo. Neuroscience Letters. 182: 107-11. PMID 7891873 DOI: 10.1016/0304-3940(94)90218-6  1
1994 Adams CE, Hoffman AF, Hudson JL, Hoffer BJ, Boyson SJ. Chronic treatment with levodopa and/or selegiline does not affect behavioral recovery induced by fetal ventral mesencephalic grafts in unilaterally 6-hydroxydopamine-lesioned rats. Experimental Neurology. 130: 261-8. PMID 7867755 DOI: 10.1006/exnr.1994.1204  1
1994 Freedman R, Strömberg I, Nordström AL, Seiger A, Olson L, Bygdeman M, Wiesel FA, Granholm AC, Hoffer BJ. Neuronal development in embryonic brain tissue derived from schizophrenic women and grafted to animal hosts. Schizophrenia Research. 13: 259-70. PMID 7841140 DOI: 10.1016/0920-9964(94)90051-5  1
1994 Hudson JL, Fong CS, Boyson SJ, Hoffer BJ. Conditioned apomorphine-induced turning in 6-OHDA-lesioned rats. Pharmacology, Biochemistry, and Behavior. 49: 147-54. PMID 7816866 DOI: 10.1016/0091-3057(94)90469-3  1
1993 Luthman J, Friedemann MN, Hoffer BJ, Gerhardt GA. In vivo electrochemical measurements of exogenous dopamine clearance in normal and neonatal 6-hydroxydopamine-treated rat striatum. Experimental Neurology. 122: 273-82. PMID 8405264 DOI: 10.1006/exnr.1993.1127  1
1993 Hudson JL, van Horne CG, Strömberg I, Brock S, Clayton J, Masserano J, Hoffer BJ, Gerhardt GA. Correlation of apomorphine- and amphetamine-induced turning with nigrostriatal dopamine content in unilateral 6-hydroxydopamine lesioned rats. Brain Research. 626: 167-74. PMID 8281427 DOI: 10.1016/0006-8993(93)90576-9  1
1993 Hudson JL, Levin DR, Hoffer BJ. A 16-channel automated rotometer system for reliable measurement of turning behavior in 6-hydroxydopamine lesioned and transplanted rats. Cell Transplantation. 2: 507-14. PMID 8167935  1
1993 Redmond DE, Hoffer BJ. IVth International Symposium on Neural Transplantation. Transcript of the closing discussion (edited) (session 44.0). Washington, D.C.: July 16, 1992. Journal of Neural Transplantation & Plasticity. 4: 113-24. PMID 7906550 DOI: 10.1155/NP.1993.113  1
1993 Luthman J, Friedemann M, Bickford P, Olson L, Hoffer BJ, Gerhardt GA. In vivo electrochemical measurements and electrophysiological studies of rat striatum following neonatal 6-hydroxydopamine treatment. Neuroscience. 52: 677-87. PMID 7680793 DOI: 10.1016/0306-4522(93)90416-D  1
1992 van Horne C, Hoffer BJ, Strömberg I, Gerhardt GA. Clearance and diffusion of locally applied dopamine in normal and 6-hydroxydopamine-lesioned rat striatum. The Journal of Pharmacology and Experimental Therapeutics. 263: 1285-92. PMID 1469634  1
1992 Freedman R, Strömberg I, Seiger A, Olson L, Nordström AL, Wiesel FA, Bygdeman M, Wetmore C, Palmer MR, Hoffer BJ. Initial studies of embryonic transplants of human hippocampus and cerebral cortex derived from schizophrenic women. Biological Psychiatry. 32: 1148-63. PMID 1362085 DOI: 10.1016/0006-3223(92)90194-5  1
1992 Hall M, Wang Y, Granholm AC, Stevens JO, Young D, Hoffer BJ. Comparison of fetal rabbit brain xenografts to three different strains of athymic nude rats: electrophysiological and immunohistochemical studies of intraocular grafts. Cell Transplantation. 1: 71-82. PMID 1344293  1
1992 Hoffer BJ, Leenders KL, Young D, Gerhardt G, Zerbe GO, Bygdeman M, Seiger A, Olson L, Strömberg I, Freedman R. Eighteen-month course of two patients with grafts of fetal dopamine neurons for severe Parkinson's disease. Experimental Neurology. 118: 243-52. PMID 1306484 DOI: 10.1016/0014-4886(92)90181-O  1
1991 Parfitt KD, Hoffer BJ, Browning MD. Norepinephrine and isoproterenol increase the phosphorylation of synapsin I and synapsin II in dentate slices of young but not aged Fisher 344 rats. Proceedings of the National Academy of Sciences of the United States of America. 88: 2361-5. PMID 1900942  1
1991 Palmer MR, Henschen A, Trok K, Hudson JL, Hoffer BJ, Olson L. Functional innervation of spinal cord tissue by fetal neocortical grafts in oculo: an electrophysiological study. Experimental Brain Research. 87: 96-107. PMID 1756836 DOI: 10.1007/BF00228510  1
1991 Giacobini MM, Hoffer BJ, Zerbe G, Olson L. Acidic and basic fibroblast growth factors augment growth of fetal brain tissue grafts. Experimental Brain Research. 86: 73-81. PMID 1721872 DOI: 10.1007/BF00231041  1
1991 Hoffer BJ, Olson L. Ethical issues in brain-cell transplantation. Trends in Neurosciences. 14: 384-8. PMID 1721747 DOI: 10.1016/0166-2236(91)90168-T  1
1990 Palmer MR, Eriksdotter-Nilsson M, Bygdeman M, Stieg P, Strömberg I, Olson L, Seiger A, Hoffer BJ, Granholm AC. Electrophysiologic effects of ethanol in human brain xenografts in oculo: antagonism by Ro15-4513. The Journal of Pharmacology and Experimental Therapeutics. 254: 1100-6. PMID 2395107  1
1990 Giacobini MM, Olson L, Hoffer BJ, Sara VR. Truncated IGF-1 exerts trophic effects on fetal brain tissue grafts. Experimental Neurology. 108: 33-7. PMID 2318286 DOI: 10.1016/0014-4886(90)90004-C  1
1990 van Horne CG, Bement S, Hoffer BJ, Gerhardt GA. Multichannel semiconductor-based electrodes for in vivo electrochemical and electrophysiological studies in rat CNS. Neuroscience Letters. 120: 249-52. PMID 2293112 DOI: 10.1016/0304-3940(90)90051-A  1
1990 Lindvall O, Rehncrona S, Brundin P, Gustavii B, Astedt B, Widner H, Lindholm T, Björklund A, Leenders KL, Rothwell JC. Neural transplantation in Parkinson's disease: the Swedish experience. Progress in Brain Research. 82: 729-34. PMID 2290977  1
1990 Palmer MR, Hoffer BJ. GABAergic mechanisms in the electrophysiological actions of ethanol on cerebellar neurons. Neurochemical Research. 15: 145-51. PMID 2185431 DOI: 10.1007/BF00972204  1
1990 Parfitt KD, Hoffer BJ, Bickford-Wimer PC. Potentiation of gamma-aminobutyric acid-mediated inhibition by isoproterenol in the cerebellar cortex: receptor specificity. Neuropharmacology. 29: 909-16. PMID 2175016 DOI: 10.1016/0028-3908(90)90141-D  1
1990 Freedman R, Olson L, Hoffer BJ. Toxic effects of lead on neuronal development and function. Environmental Health Perspectives. 89: 27-33. PMID 2088752  1
1990 Wittenberg WL, Van Horne CG, Stromberg I, Hoffer BJ. Functional enhancement of intrastriatal fetal dopamine cell grafts by the cotransplantation of peripheral nerve tissue in a rat model of Parkinson's disease Surgical Forum. 41: 502-504.  1
1989 Gerhardt GA, Friedemann M, Brodie MS, Vickroy TW, Gratton AP, Hoffer BJ, Rose GM. The effects of cholecystokinin (CCK-8) on dopamine-containing nerve terminals in the caudate nucleus and nucleus accumbens of the anesthetized rat: an in vivo electrochemical study. Brain Research. 499: 157-63. PMID 2804664 DOI: 10.1016/0006-8993(89)91146-3  1
1989 Lindvall O, Rehncrona S, Brundin P, Gustavii B, Astedt B, Widner H, Lindholm T, Björklund A, Leenders KL, Rothwell JC, Frackowiak R, Marsden D, Johnels B, Steg G, Freedman R, ... Hoffer BJ, et al. Human fetal dopamine neurons grafted into the striatum in two patients with severe Parkinson's disease. A detailed account of methodology and a 6-month follow-up. Archives of Neurology. 46: 615-31. PMID 2786405 DOI: 10.1001/archneur.1989.00520420033021  1
1989 de la Garza R, Freedman R, Hoffer BJ. Kappa-bungarotoxin blockade of nicotine electrophysiological actions in cerebellar Purkinje neurons. Neuroscience Letters. 99: 95-100. PMID 2748023 DOI: 10.1016/0304-3940(89)90271-1  1
1989 Gratton A, Hoffer BJ, Gerhardt GA. In vivo electrochemical studies of monoamine release in the medial prefrontal cortex of the rat. Neuroscience. 29: 57-64. PMID 2710348 DOI: 10.1016/0306-4522(89)90332-1  1
1989 Mahalik TJ, Strömberg I, Gerhardt GA, Granholm AC, Seiger A, Bygdeman M, Olson L, Hoffer BJ, Finger TE. Human ventral mesencephalic xenografts to the catecholamine-depleted striata of athymic rats: ultrastructure and immunocytochemistry. Synapse (New York, N.Y.). 4: 19-29. PMID 2570467 DOI: 10.1002/syn.890040104  1
1988 Hoffer BJ, Rose G, Parfitt K, Freedman R, Bickford-Wimer PC. Age-related changes in cerebellar noradrenergic function. Annals of the New York Academy of Sciences. 515: 269-86. PMID 3364888  1
1988 Miller JA, Hoffer BJ, Zahniser NR. An improved calibration procedure for computer-based quantitative autoradiography utilizing a mathematical model for the non-linear response of camera and film. Journal of Neuroscience Methods. 22: 233-8. PMID 3361949 DOI: 10.1016/0165-0270(88)90044-1  1
1988 Hoffer BJ, Granholm AC, Stevens JO, Olson L. Catecholamine-containing grafts in parkinsonism: past and present. Clinical Research. 36: 189-95. PMID 3286096  1
1988 Gratton A, Hoffer BJ, Gerhardt GA. Effects of electrical stimulation of brain reward sites on release of dopamine in rat: an in vivo electrochemical study. Brain Research Bulletin. 21: 319-24. PMID 3263894 DOI: 10.1016/0361-9230(88)90247-X  1
1988 Gratton A, Hoffer BJ, Gerhardt GA, Wise RA. Potentiation of morphine-elicited circling by dopaminergic uptake blockade. Pharmacology, Biochemistry, and Behavior. 30: 1077-9. PMID 3227032 DOI: 10.1016/0091-3057(88)90142-6  1
1988 Granholm AC, Gerhardt GA, Moore E, Eriksdotter-Nilsson M, Nylén P, Johnson AC, Henschen A, Shirley MA, Palmer MR, Hoffer BJ. Toluene exposure during maturation of intraocular brain tissue transplants: alterations of host and graft cerebellar Purkinje neuron function and sensitivity to norepinephrine. Toxicology and Applied Pharmacology. 96: 296-304. PMID 3194916 DOI: 10.1016/0041-008X(88)90088-9  1
1987 Mahowald MB, Areen J, Hoffer BJ, Jonsen AR, King P, Silver J, Sladek JR, Walters L. Transplantation of neural tissue from fetuses. Science (New York, N.Y.). 235: 1307-8. PMID 3823882  1
1987 de la Garza R, Bickford-Wimer PC, Hoffer BJ, Freedman R. Heterogeneity of nicotine actions in the rat cerebellum: an in vivo electrophysiologic study. The Journal of Pharmacology and Experimental Therapeutics. 240: 689-95. PMID 3806420  1
1987 de la Garza R, McGuire TJ, Freedman R, Hoffer BJ. The electrophysiological effects of nicotine in the rat cerebellum: evidence for direct postsynaptic actions. Neuroscience Letters. 80: 303-8. PMID 3683986 DOI: 10.1016/0304-3940(87)90472-1  1
1987 Granholm AC, Gerhardt GA, Eriksdotter-Nilsson M, Bickford-Wimer PC, Palmer MR, Seiger A, Olson L, Hoffer BJ. Age-related changes in cerebellar noradrenergic pre- and postsynaptic mechanisms: intrinsic vs extrinsic determinants evaluated with brain grafts in oculo. Brain Research. 423: 71-8. PMID 3676821 DOI: 10.1016/0006-8993(87)90826-2  1
1987 Gratton A, Hoffer BJ, Freedman R. Electrophysiological effects of phencyclidine in the medial prefrontal cortex of the rat. Neuropharmacology. 26: 1275-83. PMID 3670556 DOI: 10.1016/0028-3908(87)90087-6  1
1987 Gerhardt GA, Rose GM, Hoffer BJ. In vivo electrochemical demonstration of potassium-evoked monoamine release from rat cerebellum. Brain Research. 413: 327-35. PMID 3607482 DOI: 10.1016/0006-8993(87)91024-9  1
1987 Hall ME, Granholm AC, Stevens JO, Hoffer BJ. Myocardium and cortex cerebri xenografts transplanted into the anterior chamber of the eye of athymic rats: a morphologic and electrophysiologic profile. Neuroscience Letters. 75: 89-94. PMID 3554011 DOI: 10.1016/0304-3940(87)90081-4  1
1987 de la Garza R, McGuire TJ, Freedman R, Hoffer BJ. Selective antagonism of nicotine actions in the rat cerebellum with alpha-bungarotoxin. Neuroscience. 23: 887-91. PMID 3437995 DOI: 10.1016/0306-4522(87)90165-5  1
1987 Hoffer BJ, Olson L, Palmer MR. Toxic effects of lead in the developing nervous system: in oculo experimental models. Environmental Health Perspectives. 74: 169-75. PMID 3319551  1
1987 Hoffer BJ, Gerhardt GA, Rose GM, Strömberg I, Olson L. Voltammetric analysis of nigral graft function. Annals of the New York Academy of Sciences. 495: 510-27. PMID 3111328  1
1987 Bickford-Wimer PC, Parfitt K, Hoffer BJ, Freedman R. Desipramine and noradrenergic neurotransmission in aging: failure to respond in aged laboratory animals. Neuropharmacology. 26: 597-605. PMID 3037423 DOI: 10.1016/0028-3908(87)90153-5  1
1986 Rose GM, Gerhardt GA, Conboy GL, Hoffer BJ. Age-related alterations in monoamine release from rat striatum: an in vivo electrochemical study. Neurobiology of Aging. 7: 77-82. PMID 3960266 DOI: 10.1016/0197-4580(86)90143-0  1
1986 Gerhardt GA, Rose GM, Hoffer BJ. Release of monoamines from striatum of rat and mouse evoked by local application of potassium: evaluation of a new in vivo electrochemical technique. Journal of Neurochemistry. 46: 842-50. PMID 3950610  1
1986 Johnson SW, Hoffer BJ, Freedman R. Investigation of the failure of parenterally administered haloperidol to antagonize dopamine released from micropipettes in the caudate. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 6: 572-80. PMID 3081693  1
1986 Bickford PC, Hoffer BJ, Freedman R. Diminished interaction of norepinephrine with climbing fiber inputs to cerebellar Purkinje neurons in aged Fischer 344 rats. Brain Research. 385: 405-10. PMID 3022875 DOI: 10.1016/0006-8993(86)91092-9  1
1986 Wang Y, Palmer MR, Freedman R, Rice KC, Lessor RA, Jacobson AE, Hoffer BJ. Electrophysiological interactions of isomers of cyclazocine with the phencyclidine antagonist metaphit in rat cerebellar Purkinje neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 6: 3189-96. PMID 3021925  1
1985 Bickford PC, Hoffer BJ, Freedman R. Interaction of norepinephrine with Purkinje cell responses to cerebellar afferent inputs in aged rats. Neurobiology of Aging. 6: 89-94. PMID 4022233 DOI: 10.1016/0197-4580(85)90023-5  1
1985 Johnson SW, Hoffer BJ, Baker R, Freedman R. Correlation of Purkinje neuron depression and hypnotic effects of ethanol in inbred strains of rats. Alcoholism, Clinical and Experimental Research. 9: 56-8. PMID 3887969  1
1985 Hoffer BJ, Dunwiddie TV. Braingrafts: Potential therapy in neurodegenerative diseases and in understanding normal aging in the CNS Neurobiology of Aging. 6: 162-163. DOI: 10.1016/0197-4580(85)90038-7  1
1984 Johnson SW, Haroldsen PE, Hoffer BJ, Freedman R. Presynaptic dopaminergic activity of phencyclidine in rat caudate. The Journal of Pharmacology and Experimental Therapeutics. 229: 321-32. PMID 6707946  1
1984 Palmer MR, Olson L, Dunwiddie TV, Hoffer BJ, Seiger A. Neonatal cerebellectomy alters ethanol-induced sleep time of short sleep but not long sleep mice. Pharmacology, Biochemistry, and Behavior. 20: 153-9. PMID 6694995 DOI: 10.1016/0091-3057(84)90116-3  1
1984 Bickford PC, Mosimann WF, Hoffer BJ, Freedman R. Effects of the selective noradrenergic neurotoxin DSP4 on cerebellar Purkinje neuron electrophysiology. Life Sciences. 34: 731-41. PMID 6422177 DOI: 10.1016/0024-3205(84)90380-1  1
1984 Palmer MR, Björklund H, Taylor DA, Seiger A, Olson L, Hoffer BJ. Chronic lead exposure of the developing brain: electrophysiological abnormalities of cerebellar Purkinje neurons. Neurotoxicology. 5: 149-66. PMID 6151635  1
1984 Gerhardt GA, Palmer MR, Seiger A, Adams RN, Olson L, Hoffer BJ. Adrenergic transmission in hippocampus-locus coeruleus double grafts in oculo: demonstration by in vivo electrochemical detection. Brain Research. 306: 319-25. PMID 6087976 DOI: 10.1016/0006-8993(84)90381-0  1
1983 Björklund H, Palmer MR, Lind B, Hoffer BJ, Olson L. Postnatal lead exposure alters spontaneous cerebellar Purkinje neuron discharge. Environmental Research. 31: 448-59. PMID 6884303 DOI: 10.1016/0013-9351(83)90023-3  1
1983 Freed WJ, Ko GN, Niehoff DL, Kuhar MJ, Hoffer BJ, Olson L, Cannon-Spoor HE, Morihisa JM, Wyatt RJ. Normalization of spiroperidol binding in the denervated rat striatum by homologous grafts of substantia nigra. Science (New York, N.Y.). 222: 937-9. PMID 6635666  1
1983 Björklund H, Hoffer BJ, Palmer MR, Seiger A, Olson L. Survival and growth of neurons with enkephalin-like immunoreactivity in fetal brain areas grafted to the anterior chamber of the eye. Neuroscience. 10: 1387-98. PMID 6363968 DOI: 10.1016/0306-4522(83)90120-3  1
1983 Palmer MR, Seiger A, Hoffer BJ, Olson L. Modulatory interactions between enkephalin and catecholamines: anatomical and physiological substrates. Federation Proceedings. 42: 2934-45. PMID 6136427  1
1982 Bickford PC, Palmer MR, Hoffer BJ, Freedman R. Interactions between phencyclidine and cholinergic excitation of hippocampal pyramidal neurons. Neuropharmacology. 21: 729-32. PMID 7121744 DOI: 10.1016/0028-3908(82)90056-9  1
1982 Olson L, Björklund H, Hoffer BJ, Palmer MR, Seiger A. Spinal cord grafts: an intraocular approach to enigmas of nerve growth regulation. Brain Research Bulletin. 9: 519-37. PMID 6293662  1
1982 Mueller AL, Palmer MR, Hoffer BJ, Dunwiddie TV. Hippocampal noradrenergic responses in vivo and in vitro. Characterization of alpha and beta components. Naunyn-Schmiedeberg's Archives of Pharmacology. 318: 259-66. PMID 6281666 DOI: 10.1007/BF00501163  1
1982 Wuerthele SE, Yasuda RP, Freed WJ, Hoffer BJ. The effect of local application of homocysteine on neuronal activity in the central nervous system of the rat. Life Sciences. 31: 2683-91. PMID 6130457 DOI: 10.1016/0024-3205(82)90712-3  1
1982 Mueller AL, Kirk KL, Hoffer BJ, Dunwiddie TV. Noradrenergic responses in rat hippocampus: electrophysiological actions of direct- and indirect-acting sympathomimetics in the in vitro slice. The Journal of Pharmacology and Experimental Therapeutics. 223: 599-605. PMID 6128402  1
1981 Palmer MR, Björklund H, Freedman R, Taylor DA, Marwaha J, Olson L, Seiger A, Hoffer BJ. Permanent impairment of spontaneous Purkinje cell discharge in cerebellar grafts caused by chronic lead exposure. Toxicology and Applied Pharmacology. 60: 431-40. PMID 7292481  1
1981 Bickford PC, Palmer MR, Rice KC, Hoffer BJ, Freedman R. Electrophysiological effects of phencyclidine on rat hippocampal pyramidal neurons. Neuropharmacology. 20: 733-42. PMID 7279144 DOI: 10.1016/0028-3908(81)90221-5  1
1981 Wuerthele SM, Freed WJ, Olson L, Morihisa J, Spoor L, Wyatt RJ, Hoffer BJ. Effect of dopamine agonists and antagonists on the electrical activity of substantia nigra neurons transplanted into the lateral ventricle of the rat. Experimental Brain Research. 44: 1-10. PMID 7274357  1
1981 Freed WJ, Morihisa JM, Spoor E, Hoffer BJ, Olson L, Seiger A, Wyatt RJ. Transplanted adrenal chromaffin cells in rat brain reduce lesion-induced rotational behaviour. Nature. 292: 351-2. PMID 7254334  1
1981 Marwaha J, Hoffer BJ, Freedman R. Electrophysiologic evidence for histamine receptors in rat cerebellum. Experimental Neurology. 74: 285-92. PMID 6793381  0.68
1981 Marwaha J, Hoffer BJ, Freedman R. Changes in noradrenergic neurotransmission in rat cerebellum during aging. Neurobiology of Aging. 2: 95-8. PMID 6272145  0.68
1981 Palmer MR, Mathews WR, Hoffer BJ, Murphy RC. Electrophysiological response of cerebellar Purkinje neurons to leukotriene D4 and B4. The Journal of Pharmacology and Experimental Therapeutics. 219: 91-6. PMID 6270301  1
1981 Dunwiddie TV, Hoffer BJ, Fredholm BB. Alkylxanthines elevate hippocampal excitability. Evidence for a role of endogenous adenosine. Naunyn-Schmiedeberg's Archives of Pharmacology. 316: 326-30. PMID 6267486 DOI: 10.1007/BF00501365  1
1981 Mueller AL, Hoffer BJ, Dunwiddie TV. Noradrenergic responses in rat hippocampus: evidence for medication by alpha and beta receptors in the in vitro slice. Brain Research. 214: 113-26. PMID 6263414 DOI: 10.1016/0006-8993(81)90442-X  1
1981 Marwaha J, Hoffer BJ, Geller HM, Freedman R. Electrophysiologic interactions of antipsychotic drugs with central noradrenergic pathways. Psychopharmacology. 73: 126-33. PMID 6112771 DOI: 10.1007/BF00429202  1
1980 Freed WJ, Perlow MJ, Karoum F, Seiger A, Olson L, Hoffer BJ, Wyatt RJ. Restoration of dopaminergic function by grafting of fetal rat substantia nigra to the caudate nucleus: long-term behavioral, biochemical, and histochemical studies. Annals of Neurology. 8: 510-9. PMID 7436393 DOI: 10.1002/ana.410080508  1
1980 Palmer MR, Wuerthele SM, Hoffer BJ. Physical and physiological characteristics of micropressure ejection of drugs from multibarreled pipettes. Neuropharmacology. 19: 931-8. PMID 7422075 DOI: 10.1016/0028-3908(80)90001-5  1
1980 Taylor D, Freedman R, Seiger A, Olson L, Hoffer BJ. Conditions for adrenergic hyperinnervation in hippocampus: II. Electrophysiological evidence from intraocular double grafts. Experimental Brain Research. 39: 289-99. PMID 7398824  1
1980 Olson L, Seiger A, Taylor D, Freedman R, Hoffer BJ. Conditions for adrenergic hyperinnervation in hippocampus: I. Histochemical evidence from intraocular double grafts. Experimental Brain Research. 39: 277-88. PMID 7398823  1
1980 Oliver AP, Carman JS, Hoffer BJ, Wyatt RJ. Effect of altered calcium ion concentration on interictal spike generation in the hippocampal slice. Experimental Neurology. 68: 489-99. PMID 7379894  0.84
1980 Oliver AP, Hoffer BJ, Wyatt RJ. Kindling induces long-lasting alterations in response of hippocampal neurons to elevated potassium levels in vitro. Science (New York, N.Y.). 208: 1264-5. PMID 7375936  0.84
1980 Moises HC, Hoffer BJ, Woodward DJ. GABA facilitation by noradrenaline shows supersensitivity in cerebellum after 6-hydroxydopamine. Naunyn-Schmiedeberg's Archives of Pharmacology. 315: 37-46. PMID 7242692 DOI: 10.1007/BF00504228  1
1980 Palmer MR, Mathews R, Murphy RC, Hoffer BJ. Leukotriene C elicits a prolonged excitation of cerebellar Purkinje neurons. Neuroscience Letters. 18: 173-80. PMID 7052488 DOI: 10.1016/0304-3940(80)90322-5  1
1980 Marwaha J, Palmer MR, Woodward DJ, Hoffer BJ, Freedman R. Electrophysiological evidence for presynaptic actions of phencyclidine on noradrenergic transmission in rat cerebellum. The Journal of Pharmacology and Experimental Therapeutics. 215: 606-13. PMID 6255134  1
1980 Geller HM, Hoffer BJ, Taylor DA. Electrophysiological actions of benzodiazepines. Federation Proceedings. 39: 3016-23. PMID 6252064  1
1980 Dunwiddie TV, Hoffer BJ. Adenine nucleotides and synaptic transmission in the in vitro rat hippocampus. British Journal of Pharmacology. 69: 59-68. PMID 6247005 DOI: 10.1111/j.1476-5381.1980.tb10883.x  1
1980 Palmer MR, Hoffer BJ. Catecholamine modulation of enkephalin-induced electrophysiological responses in cerebral cortex. The Journal of Pharmacology and Experimental Therapeutics. 213: 205-15. PMID 6102598  1
1979 Perlow MJ, Freed WJ, Hoffer BJ, Seiger A, Olson L, Wyatt RJ. Brain grafts reduce motor abnormalities produced by destruction of nigrostriatal dopamine system. Science (New York, N.Y.). 204: 643-7. PMID 571147  1
1979 Meuller AL, Dunwiddie TV, Palmer MR, Lee HK, Stewart JM, Hoffer BJ. Enkephalins and hippocampal neuronal circuits. Proceedings of the Western Pharmacology Society. 22: 471-4. PMID 515091  1
1979 Woodward DJ, Moises HC, Waterhouse BD, Hoffer BJ, Freedman R. Modulatory actions of norepinephrine in the central nervous system. Federation Proceedings. 38: 2109-16. PMID 446766  1
1979 Freedman R, Taylor DA, Seiger A, Olson L, Hoffer BJ. Seizures and related epileptiform activity in hippocampus transplanted to the anterior chamber of the eye: modulation by cholinergic and adrenergic input. Annals of Neurology. 6: 281-95. PMID 233411 DOI: 10.1002/ana.410060402  1
1979 Smellie FW, Daly JW, Dunwiddie TV, Hoffer BJ. The dextro and levorotatory isomers of N-phenylisopropyladenosine: stereospecific effects on cyclic AMP-formation and evoked synaptic responses in brain slices. Life Sciences. 25: 1739-48. PMID 231163 DOI: 10.1016/0024-3205(79)90477-6  1
1979 Lee HK, Dunwiddie TV, Hoffer BJ. Interaction of diazepam with synaptic transmission in the in vitro rat hippocampus. Naunyn-Schmiedeberg's Archives of Pharmacology. 309: 131-6. PMID 230418 DOI: 10.1007/BF00501220  1
1979 Moises HC, Woodward DJ, Hoffer BJ, Freedman R. Interactions of norepinephrine with Purkinje cell responses to putative amino acid neurotransmitters applied by microiontophoresis. Experimental Neurology. 64: 493-515. PMID 223861 DOI: 10.1016/0014-4886(79)90227-9  1
1978 Oliver AP, Hoffer BJ, Wyatt RJ. Interaction of potassium and calcium in penicillin-induced interictal spike discharge in the hippocampal slice. Experimental Neurology. 62: 510-20. PMID 220073  0.84
1978 Palmer MR, Morris DH, Taylor DA, Stewart JM, Hoffer BJ. Electrophysiological effects of enkephalin analogs in rat cortex. Life Sciences. 23: 851-60. PMID 212657  0.76
1978 Smith BM, Hoffer BJ. A gated, high voltage iontophoresis system with accurate current monitoring. Electroencephalography and Clinical Neurophysiology. 44: 398-402. PMID 76547 DOI: 10.1016/0013-4694(78)90316-4  1
1978 Geller HM, Taylor DA, Hoffer BJ. Benzodiazepines and central inhibitory mechanisms. Naunyn-Schmiedeberg's Archives of Pharmacology. 304: 81-8. PMID 30047 DOI: 10.1007/BF00495542  1
1977 Wise RA, Hoffer BJ. Equal suppression of cerebellar Purkinje cell activity by amphetamine stereoisomers. Physiology & Behavior. 18: 1005-9. PMID 928521 DOI: 10.1016/0031-9384(77)90003-8  1
1977 Freedman R, Hoffer BJ, Woodward DJ, Puro D. Interaction of norepinephrine with cerebellar activity evoked by mossy and climbing fibers. Experimental Neurology. 55: 269-88. PMID 849758 DOI: 10.1016/0014-4886(77)90175-3  1
1977 Geller HM, Hoffer BJ. Effect of calcium removal on monoamine-elicited depressions of cultured tuberal neurons. Journal of Neurobiology. 8: 43-55. PMID 839210 DOI: 10.1002/neu.480080104  1
1977 Hoffer BJ, Seiger A, Taylor D, Olson L, Freedman R. Seizures and related epileptiform activity in hippocampus transplanted to the anterior chamber of the eye I. Characterization of seizures, interictal spikes, and synchronous activity. Experimental Neurology. 54: 233-50. PMID 838015  1
1977 Oliver AP, Hoffer BJ, Wyatt RJ. The hippocampal slice: a system for studying the pharmacology of seizures and for screening anticonvulsant drugs. Epilepsia. 18: 543-8. PMID 579341  0.84
1977 Woodward DJ, Seiger A, Olson L, Hoffer BJ. Intrinsic and extrinsic determinants of dendritic development as revealed by Golgi studies of cerebellar and hippocampal transplants in oculo. Experimental Neurology. 57: 984-98. PMID 72681  1
1976 Nathanson JA, Freedman R, Hoffer BJ. Lanthanum inhibits brain adenylate cyclase and blocks noradrenergic depression of Purkinje cell discharge independent of calcium. Nature. 261: 330-2. PMID 1272410 DOI: 10.1038/261330a0  1
1976 Freedman R, Hoffer BJ, Puro D, Woodward DJ. Noradrenaline modulation of the responses of the cerebellar Purkinje cell to afferent synaptic activity. British Journal of Pharmacology. 57: 603-5. PMID 963346  1
1976 Siggins GR, Hoffer BJ, Bloom FE, Ungerstedt U. Cytochemical and electrophysiological studies of dopamine in the caudate nucleus. Research Publications - Association For Research in Nervous and Mental Disease. 55: 227-48. PMID 188086  1
1976 Hoffer BJ, Freedman R. Beta-adrenergic-control of cyclic AMP-generating systems in cerebellum: pharmacological heterogeneity confirmed by destruction of interneurons. Experimental Neurology. 51: 653-67. PMID 179837 DOI: 10.1016/0014-4886(76)90188-6  1
1976 Skolnick P, Daly JW, Freedman R, Hoffer BJ. Interrelationship between catecholamine-stimulated formation of adenosine 3',5'-monophosphate in cerebellar slices and inhibitory effects on cerebellar Purkinje cells: antagonism by neuroleptic compounds. The Journal of Pharmacology and Experimental Therapeutics. 197: 280-92. PMID 5595  0.68
1975 Freedman R, Hoffer BJ, Woodward DJ. A quantitative microiontophoretic analysis of the responses of central neurones to noradrenaline: interactions with cobalt, manganese, verapamil and dichloroisoprenaline. British Journal of Pharmacology. 54: 529-39. PMID 240474  1
1975 Hoffer BJ, Siggins GR. Electrophysiological techniques for the study of hormone action in the central nervous system. Methods in Enzymology. 39: 429-40. PMID 239301 DOI: 10.1016/S0076-6879(75)39038-1  1
1975 Freedman R, Hoffer BJ. Phenothiazine antagonism of the noradrenergic inhibition of cerebellar Purkinje neurons. Journal of Neurobiology. 6: 277-88. PMID 171341 DOI: 10.1002/neu.480060304  0.68
1975 Bloom FE, Siggins GR, Hoffer BJ, Segal M, Oliver AP. Cyclic nucleotdides in the central synaptic actions of catecholamines. Advances in Cyclic Nucleotide Research. 5: 603-18. PMID 165689  1
1975 Shoemaker WJ, Balentine LT, Siggins GR, Hoffer BJ, Henriksen SJ, Bloom FE. Characteristics of the release of adenosine 3':5'-monophosphate from micropipets by microiontophoresis. Journal of Cyclic Nucleotide Research. 1: 97-106. PMID 4474  1
1974 Siggins GR, Hoffer BJ, Ungerstedt U. Electrophysiological evidence for involvement of cyclic adenosine monophosphate in dopamine responses of caudate neurons. Life Sciences. 15: 779-92. PMID 4378085 DOI: 10.1016/0024-3205(74)90298-7  1
1974 Bloom FE, Siggins GR, Hoffer BJ. Interpreting the failures to confirm the depression of cerebellar Purkinje cells by cyclic AMP. Science (New York, N.Y.). 185: 627-9. PMID 4366788  1
1974 Woodward DJ, Hoffer BJ, Altman J. Physiological and pharmacological properties of Purkinje cells in rat cerebellum degranulated by postnatal x-irradiation. Journal of Neurobiology. 5: 283-304. PMID 4155719 DOI: 10.1002/neu.480050402  1
1973 Bloom FE, Chu N, Hoffer BJ, Nelson CN, Siggins GR. Studies on the function of central noradrenergic neurons. Neurosciences Research. 5: 53-72. PMID 4366084  1
1973 Hoffer BJ, Siggins GR, Oliver AP, Bloom FE. Activation of the pathway from locus coeruleus to rat cerebellar Purkinje neurons: pharmacological evidence of noradrenergic central inhibition. The Journal of Pharmacology and Experimental Therapeutics. 184: 553-69. PMID 4347049  1
1973 Siggins GR, Battenberg EF, Hoffer BJ, Bloom FE, Steiner AL. Noradrenergic stimulation of cyclic adenosine monophosphate in rat Purkinje neurons: an immunocytochemical study. Science (New York, N.Y.). 179: 585-8. PMID 4346826  1
1973 Nelson CN, Hoffer BJ, Chu NS, Bloom FE. Cytochemical and pharmacological studies on polysensory neurons in the primate frontal cortex. Brain Research. 62: 115-33. PMID 4148775  1
1972 Hoffer BJ, Siggins GR, Oliver AP, Bloom FE. Cyclic AMP-mediated adrenergic synapses to cerebellar Purkinje cells. Advances in Cyclic Nucleotide Research. 1: 411-23. PMID 4353180  1
1972 Bloom FE, Hoffer BJ, Battenberg ER, Siggins GR, Steiner AL, Parker CW, Wedner HJ. Adenosine 3',5'-monophosphate is localized in cerebellar neurons: immunofluorescence evidence. Science (New York, N.Y.). 177: 436-8. PMID 4339615  1
1972 Bloom FE, Hoffer BJ, Siggins GR. Norepinephrine mediated cerebellar synapses: a model system for neuropsychopharmacology. Biological Psychiatry. 4: 157-77. PMID 4337435  1
1972 Bloom FE, Hoffer BJ, Siggins GR, Barker JL, Nicoll RA. Effects of serotonin on central neurons: microiontophoretic administration. Federation Proceedings. 31: 97-106. PMID 4333253  1
1972 Wedner HF, Hoffer BJ, Battenberg EB, Steiner AL, Parker CW, Bloom FE. A method for detecting intracellular cyclic adenosine monophosphate by immunofluorescence. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 20: 293-5. PMID 4113297  1
1971 Bloom FE, Hoffer BJ, Siggins GR. Studies on norepinephrine-containing afferents to Purkinje cells of art cerebellum. I. Localization of the fibers and their synapses. Brain Research. 25: 501-21. PMID 5544323 DOI: 10.1016/0006-8993(71)90457-4  1
1971 Hoffer BJ, Neff NH, Siggins GR. Microiontophoretic release of norepinephrine from micropipettes. Neuropharmacology. 10: 175-80. PMID 5093958 DOI: 10.1016/0028-3908(71)90038-4  1
1971 Siggins GR, Hoffer BJ, Oliver AP, Bloom FE. Activation of a central noradrenergic projection to cerebellum. Nature. 233: 481-3. PMID 4939543 DOI: 10.1038/233481a0  1
1971 Hoffer BJ, Siggins GR, Bloom FE. Studies on norepinephrine-containing afferents to Purkinje cells of rat cerebellum. II. Sensitivity of Purkinje cells to norepinephrine and related substances administered by microiontophoresis. Brain Research. 25: 523-34. PMID 4395919 DOI: 10.1016/0006-8993(71)90458-6  1
1971 Godfraind JM, Pumain R, Siggins GR, Hoffer BJ, Bloom FE. Cyclic adenosine monophosphate and norepinephrine: effect on purkinje cells in rat cerebellar cortex. Science (New York, N.Y.). 174: 1257-9. PMID 4332286  1
1971 Lapham LW, Lentz RD, Woodward DJ, Hoffer BJ, Herman CJ. Postnatal development of tetraploid DNA content in the Purkinje neuron of the rat: an aspect of cellular differentiation. Ucla Forum in Medical Sciences. 14: 61-71. PMID 4331240  1
1971 Woodward DJ, Hoffer BJ, Siggins GR, Bloom FE. The ontogenetic development of synaptic junctions, synaptic activation and responsiveness to neurotransmitter substances in rat cerebellar purkinje cells. Brain Research. 34: 73-97. PMID 4330971 DOI: 10.1016/0006-8993(71)90352-0  1
1971 Hoffer BJ, Siggins GR, Oliver AP, Bloom FE. Cyclic AMP mediation of norepinephrine inhibition in rat cerebellar cortex: a unique class of synaptic responses. Annals of the New York Academy of Sciences. 185: 531-49. PMID 4330518  1
1971 Woodward DJ, Hoffer BJ, Siggins GR, Oliver AP. Inhibition of Purkinje cells in the frog cerebellum. II. Evidence for GABA as the inhibitory transmitter. Brain Research. 33: 91-100. PMID 4330216 DOI: 10.1016/0006-8993(71)90308-8  1
1971 Hoffer BJ, Siggins GR, Woodward DJ, Bloom FE. Spontaneous discharge of Purkinje neurons after destruction of catecholamine-containing afferents by 6-hydroxydopamine. Brain Research. 30: 425-30. PMID 4329214 DOI: 10.1016/0006-8993(71)90095-3  1
1971 Siggins GR, Hoffer BJ, Bloom FE. Studies on norepinephrine-containing afferents to Purkinje cells of rat cerebellum. 3. Evidence for mediation of norepinephrine effects by cyclic 3',5'-adenosine monophosphate. Brain Research. 25: 535-53. PMID 4322679 DOI: 10.1016/0006-8993(71)90459-8  1
1971 Siggins GR, Oliver AP, Hoffer BJ, Bloom FE. Cyclic adenosine monophosphate and norepinephrine: effects on transmembrane properties of cerebellar Purkinje cells. Science (New York, N.Y.). 171: 192-4. PMID 4322158  1
1970 Hoffer BJ, Siggins GR, Bloom FE. Possible cyclic AMP-mediated adrenergic synapses to rat cerebellar Purkinje cells: combined structural, physiological, and pharmacological analyses. Advances in Biochemical Psychopharmacology. 3: 349-70. PMID 4331463  1
1969 Woodward DJ, Hoffer BJ, Lapham LW. Postnatal development of electrical and enzyme histochemical activity in Purkinje cells. Experimental Neurology. 23: 120-39. PMID 5765001  1
1969 Hoffer BJ, Siggins GR, Bloom FE. Prostaglandins E1 and E2 antagonize norepinephrine effects on cerebellar purkinje cells: microelectrophoretic study. Science (New York, N.Y.). 166: 1418-20. PMID 5350346  1
1969 Siggins GR, Hoffer BJ, Bloom FE. Cyclic adenosine monophosphate: possible mediator for norepinephrine effects on cerebellar Purkinje cells. Science (New York, N.Y.). 165: 1018-20. PMID 4308638  1
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