Patrick S. Daugherty - Publications

Affiliations: 
University of California, Santa Barbara, Santa Barbara, CA, United States 
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76 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Paull ML, Bozekowski JD, Daugherty PS. Mapping antibody binding using multiplexed epitope substitution analysis. Journal of Immunological Methods. 499: 113178. PMID 34757083 DOI: 10.1016/j.jim.2021.113178  0.344
2020 Kamath K, Reifert J, Johnston T, Gable C, Pantazes RJ, Rivera HN, McAuliffe I, Handali S, Daugherty PS. Antibody epitope repertoire analysis enables rapid antigen discovery and multiplex serology. Scientific Reports. 10: 5294. PMID 32210339 DOI: 10.1038/S41598-020-62256-9  0.439
2020 Yoo JI, Daugherty PS, O'Malley MA. Bridging non-overlapping reads illuminates high-order epistasis between distal protein sites in a GPCR. Nature Communications. 11: 690. PMID 32019920 DOI: 10.1038/S41467-020-14495-7  0.354
2019 Paull ML, Johnston T, Ibsen KN, Bozekowski JD, Daugherty PS. A general approach for predicting protein epitopes targeted by antibody repertoires using whole proteomes. Plos One. 14: e0217668. PMID 31490930 DOI: 10.1371/Journal.Pone.0217668  0.398
2018 Ballew JT, Reifert JR, Daugherty PS. Antibody Biomarker Discovery Via In Vitro Evolution of Peptides. Methods in Molecular Biology (Clifton, N.J.). 1785: 249-268. PMID 29714024 DOI: 10.1007/978-1-4939-7841-0_17  0.819
2018 Stach N, Kalinska M, Zdzalik M, Kitel R, Karim A, Serwin K, Rut W, Larsen K, Jabaiah A, Firlej M, Wladyka B, Daugherty P, Stennicke H, Drag M, Potempa J, et al. Unique Substrate Specificity of SplE Serine Protease from Staphylococcus aureus. Structure (London, England : 1993). PMID 29526434 DOI: 10.1016/J.Str.2018.02.008  0.797
2018 Bozekowski J, Graham AJ, Daugherty PS. High-titer antibody depletion enhances discovery of diverse serum antibody specificities. Journal of Immunological Methods. PMID 29360471 DOI: 10.1016/J.Jim.2018.01.003  0.388
2018 Paull ML, Daugherty PS. Mapping serum antibody repertoires using peptide libraries Current Opinion in Chemical Engineering. 19: 21-26. DOI: 10.1016/J.Coche.2017.12.001  0.446
2017 Ibsen KN, Daugherty PS. Prediction of antibody structural epitopes via random peptide library screening and next generation sequencing. Journal of Immunological Methods. PMID 28827189 DOI: 10.1016/J.Jim.2017.08.004  0.478
2016 Guerrero JL, Daugherty PS, O'Malley MA. Emerging technologies for protease engineering: New tools to clear out disease. Biotechnology and Bioengineering. PMID 27497426 DOI: 10.1002/Bit.26066  0.431
2016 Pantazes RJ, Reifert J, Bozekowski J, Ibsen KN, Murray JA, Daugherty PS. Identification of disease-specific motifs in the antibody specificity repertoire via next-generation sequencing. Scientific Reports. 6: 30312. PMID 27481573 DOI: 10.1038/Srep30312  0.458
2016 Elliott SE, Parchim NF, Kellems RE, Xia Y, Soffici AR, Daugherty PS. A pre-eclampsia-associated Epstein-Barr virus antibody cross-reacts with placental GPR50. Clinical Immunology (Orlando, Fla.). PMID 27181993 DOI: 10.1016/J.Clim.2016.05.002  0.431
2016 Guerrero JL, O'Malley MA, Daugherty PS. Intracellular FRET-based screen for redesigning the specificity of secreted proteases. Acs Chemical Biology. PMID 26730612 DOI: 10.1021/Acschembio.5B01051  0.508
2015 Shivange AV, Daugherty PS. De novo discovery of bioactive cyclic peptides using bacterial display and flow cytometry. Methods in Molecular Biology (Clifton, N.J.). 1248: 139-53. PMID 25616331 DOI: 10.1007/978-1-4939-2020-4_10  0.53
2014 Elliott SE, Parchim NF, Liu C, Xia Y, Kellems RE, Soffici AR, Daugherty PS. Characterization of antibody specificities associated with preeclampsia. Hypertension. 63: 1086-93. PMID 24446060 DOI: 10.1161/Hypertensionaha.113.02362  0.452
2014 Spatola BN, Kaukinen K, Collin P, Mäki M, Kagnoff MF, Daugherty PS. Persistence of elevated deamidated gliadin peptide antibodies on a gluten-free diet indicates nonresponsive coeliac disease. Alimentary Pharmacology & Therapeutics. 39: 407-17. PMID 24392888 DOI: 10.1111/Apt.12603  0.797
2014 Shropshire TD, Reifert J, Rajagopalan S, Baker D, Feinstein SC, Daugherty PS. Amyloid β peptide cleavage by kallikrein 7 attenuates fibril growth and rescues neurons from Aβ-mediated toxicity in vitro. Biological Chemistry. 395: 109-18. PMID 23989112 DOI: 10.1515/Hsz-2013-0230  0.791
2013 Henriques ST, Thorstholm L, Huang YH, Getz JA, Daugherty PS, Craik DJ. A novel quantitative kinase assay using bacterial surface display and flow cytometry. Plos One. 8: e80474. PMID 24260399 DOI: 10.1371/Journal.Pone.0080474  0.785
2013 Ballew JT, Murray JA, Collin P, Mäki M, Kagnoff MF, Kaukinen K, Daugherty PS. Antibody biomarker discovery through in vitro directed evolution of consensus recognition epitopes. Proceedings of the National Academy of Sciences of the United States of America. 110: 19330-5. PMID 24222690 DOI: 10.1073/Pnas.1314792110  0.804
2013 Desnoyers LR, Vasiljeva O, Richardson JH, Yang A, Menendez EE, Liang TW, Wong C, Bessette PH, Kamath K, Moore SJ, Sagert JG, Hostetter DR, Han F, Gee J, Flandez J, ... ... Daugherty PS, et al. Tumor-specific activation of an EGFR-targeting probody enhances therapeutic index. Science Translational Medicine. 5: 207ra144. PMID 24132639 DOI: 10.1126/Scitranslmed.3006682  0.333
2013 Zdzalik M, Kalinska M, Wysocka M, Stec-Niemczyk J, Cichon P, Stach N, Gruba N, Stennicke HR, Jabaiah A, Markiewicz M, Kedracka-Krok S, Wladyka B, Daugherty PS, Lesner A, Rolka K, et al. Biochemical and structural characterization of SplD protease from Staphylococcus aureus. Plos One. 8: e76812. PMID 24130791 DOI: 10.1371/Journal.Pone.0076812  0.817
2013 Getz JA, Cheneval O, Craik DJ, Daugherty PS. Design of a cyclotide antagonist of neuropilin-1 and -2 that potently inhibits endothelial cell migration. Acs Chemical Biology. 8: 1147-54. PMID 23537207 DOI: 10.1021/Cb4000585  0.829
2013 Spatola BN, Murray JA, Kagnoff M, Kaukinen K, Daugherty PS. Antibody repertoire profiling using bacterial display identifies reactivity signatures of celiac disease. Analytical Chemistry. 85: 1215-22. PMID 23234559 DOI: 10.1021/Ac303201D  0.819
2012 Elliott SE, Soffici AR, Daugherty PS. OS042. Discovery and characterization of antibody biomarkers ofpre-eclampsia and reagents for their detection Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health. 2: 199-200. PMID 26105256 DOI: 10.1016/J.Preghy.2012.04.043  0.493
2012 Jabaiah AM, Getz JA, Witkowski WA, Hardy JA, Daugherty PS. Identification of protease exosite-interacting peptides that enhance substrate cleavage kinetics. Biological Chemistry. 393: 933-41. PMID 22944693 DOI: 10.1515/Hsz-2012-0162  0.83
2012 Erster O, Thomas JM, Hamzah J, Jabaiah AM, Getz JA, Schoep TD, Hall SS, Ruoslahti E, Daugherty PS. Site-specific targeting of antibody activity in vivo mediated by disease-associated proteases. Journal of Controlled Release : Official Journal of the Controlled Release Society. 161: 804-12. PMID 22634092 DOI: 10.1016/J.Jconrel.2012.05.035  0.773
2012 Getz JA, Schoep TD, Daugherty PS. Peptide discovery using bacterial display and flow cytometry. Methods in Enzymology. 503: 75-97. PMID 22230566 DOI: 10.1016/B978-0-12-396962-0.00004-5  0.84
2012 Kalińska M, Kantyka T, Greenbaum DC, Larsen KS, Władyka B, Jabaiah A, Bogyo M, Daugherty PS, Wysocka M, Jaros M, Lesner A, Rolka K, Schaschke N, Stennicke H, Dubin A, et al. Substrate specificity of Staphylococcus aureus cysteine proteases--Staphopains A, B and C. Biochimie. 94: 318-27. PMID 21802486 DOI: 10.1016/J.Biochi.2011.07.020  0.796
2011 Getz JA, Rice JJ, Daugherty PS. Protease-resistant peptide ligands from a knottin scaffold library. Acs Chemical Biology. 6: 837-44. PMID 21615106 DOI: 10.1021/Cb200039S  0.838
2011 Jabaiah A, Daugherty PS. Directed evolution of protease beacons that enable sensitive detection of endogenous MT1-MMP activity in tumor cell lines. Chemistry & Biology. 18: 392-401. PMID 21439484 DOI: 10.1016/J.Chembiol.2010.12.017  0.817
2011 Little LE, Dane KY, Daugherty PS, Healy KE, Schaffer DV. Exploiting bacterial peptide display technology to engineer biomaterials for neural stem cell culture. Biomaterials. 32: 1484-94. PMID 21129772 DOI: 10.1016/J.Biomaterials.2010.10.032  0.811
2010 Xiao Y, Dane KY, Uzawa T, Csordas A, Qian J, Soh HT, Daugherty PS, Lagally ET, Heeger AJ, Plaxco KW. Detection of telomerase activity in high concentration of cell lysates using primer-modified gold nanoparticles. Journal of the American Chemical Society. 132: 15299-307. PMID 20932008 DOI: 10.1021/Ja106513F  0.754
2010 Boulware KT, Jabaiah A, Daugherty PS. Evolutionary optimization of peptide substrates for proteases that exhibit rapid hydrolysis kinetics. Biotechnology and Bioengineering. 106: 339-46. PMID 20148412 DOI: 10.1002/Bit.22693  0.808
2010 Karim AY, Kulczycka M, Kantyka T, Dubin G, Jabaiah A, Daugherty PS, Thogersen IB, Enghild JJ, Nguyen KA, Potempa J. A novel matrix metalloprotease-like enzyme (karilysin) of the periodontal pathogen Tannerella forsythia ATCC 43037. Biological Chemistry. 391: 105-17. PMID 19919176 DOI: 10.1515/Bc.2010.009  0.803
2010 Kenrick SA, Daugherty PS. Bacterial display enables efficient and quantitative peptide affinity maturation. Protein Engineering, Design & Selection : Peds. 23: 9-17. PMID 19903738 DOI: 10.1093/Protein/Gzp065  0.821
2009 Thomas JM, Daugherty PS. Proligands with protease-regulated binding activity identified from cell-displayed prodomain libraries. Protein Science : a Publication of the Protein Society. 18: 2053-9. PMID 19653300 DOI: 10.1002/Pro.217  0.704
2009 Hall SS, Daugherty PS. Quantitative specificity-based display library screening identifies determinants of antibody-epitope binding specificity. Protein Science : a Publication of the Protein Society. 18: 1926-34. PMID 19610073 DOI: 10.1002/Pro.203  0.706
2009 Dane KY, Gottstein C, Daugherty PS. Cell surface profiling with peptide libraries yields ligand arrays that classify breast tumor subtypes. Molecular Cancer Therapeutics. 8: 1312-8. PMID 19417151 DOI: 10.1158/1535-7163.Mct-08-1105  0.796
2009 Stec-Niemczyk J, Pustelny K, Kisielewska M, Bista M, Boulware KT, Stennicke HR, Thogersen IB, Daugherty PS, Enghild JJ, Baczynski K, Popowicz GM, Dubin A, Potempa J, Dubin G. Structural and functional characterization of SplA, an exclusively specific protease of Staphylococcus aureus. The Biochemical Journal. 419: 555-64. PMID 19175361 DOI: 10.1042/Bj20081351  0.812
2009 Sooter LJ, Stratis-Cullum DN, Zhang Y, Rice JJ, Ballew JT, Soh HT, Daugherty PS, Pellegrino P, Stagliano N. Hand held biowarfare assays: Rapid biowarfare detection using the combined attributes of microfluidic in vitro selections and immunochromatographic assays Acs Symposium Series. 1016: 73-83. DOI: 10.1021/bk-2009-1016.ch006  0.771
2008 Kim U, Qian J, Kenrick SA, Daugherty PS, Soh HT. Multitarget dielectrophoresis activated cell sorter. Analytical Chemistry. 80: 8656-61. PMID 18939853 DOI: 10.1021/Ac8015938  0.752
2008 Rice JJ, Daugherty PS. Directed evolution of a biterminal bacterial display scaffold enhances the display of diverse peptides. Protein Engineering, Design & Selection : Peds. 21: 435-42. PMID 18480093 DOI: 10.1093/Protein/Gzn020  0.719
2008 Dubin G, Stec-Niemczyk J, Kisielewska M, Pustelny K, Popowicz GM, Bista M, Kantyka T, Boulware KT, Stennicke HR, Czarna A, Phopaisarn M, Daugherty PS, Thøgersen IB, Enghild JJ, Thornberry N, et al. Enzymatic activity of the Staphylococcus aureus SplB serine protease is induced by substrates containing the sequence Trp-Glu-Leu-Gln. Journal of Molecular Biology. 379: 343-56. PMID 18448121 DOI: 10.1016/J.Jmb.2008.03.059  0.803
2007 Kenrick S, Rice J, Daugherty P. Flow cytometric sorting of bacterial surface-displayed libraries Current Protocols in Cytometry / Editorial Board, J. Paul Robinson, Managing Editor ... [Et Al.]. Unit4.6. PMID 18770852 DOI: 10.1002/0471142956.Cy0406S42  0.832
2007 Kim U, Shu CW, Dane KY, Daugherty PS, Wang JY, Soh HT. Selection of mammalian cells based on their cell-cycle phase using dielectrophoresis. Proceedings of the National Academy of Sciences of the United States of America. 104: 20708-12. PMID 18093921 DOI: 10.1073/Pnas.0708760104  0.742
2007 Daugherty PS. Protein engineering with bacterial display. Current Opinion in Structural Biology. 17: 474-80. PMID 17728126 DOI: 10.1016/J.Sbi.2007.07.004  0.405
2007 Hall SS, Mitragotri S, Daugherty PS. Identification of peptide ligands facilitating nanoparticle attachment to erythrocytes. Biotechnology Progress. 23: 749-54. PMID 17469847 DOI: 10.1021/Bp060333L  0.709
2007 Bessette PH, Hu X, Soh HT, Daugherty PS. Microfluidic library screening for mapping antibody epitopes. Analytical Chemistry. 79: 2174-8. PMID 17253874 DOI: 10.1021/Ac0616916  0.444
2007 Stratis-Cullum DN, Sooter LJ, Zhang Y, Daugherty PS, Soh HT, Pellegrino P, Stagliano N. Affinity reagent technology development and application to rapid immunochromatographic pathogen detection Proceedings of Spie - the International Society For Optical Engineering. 6759. DOI: 10.1117/12.732731  0.347
2007 Dane KY, Suit LA, Daugherty PS. Selection of peptides internalizing into tumor cells using fluorescent bacterial display libraries Aiche Annual Meeting, Conference Proceedings 0.819
2006 Oh SH, Lee SH, Kenrick SA, Daugherty PS, Soh HT. Microfluidic protein detection through genetically engineered bacterial cells. Journal of Proteome Research. 5: 3433-7. PMID 17137345 DOI: 10.1021/Pr060193A  0.786
2006 You X, Nguyen AW, Jabaiah A, Sheff MA, Thorn KS, Daugherty PS. Intracellular protein interaction mapping with FRET hybrids. Proceedings of the National Academy of Sciences of the United States of America. 103: 18458-63. PMID 17130455 DOI: 10.1073/Pnas.0605422103  0.806
2006 Mena MA, Treynor TP, Mayo SL, Daugherty PS. Blue fluorescent proteins with enhanced brightness and photostability from a structurally targeted library. Nature Biotechnology. 24: 1569-71. PMID 17115054 DOI: 10.1038/Nbt1264  0.625
2006 Boulware KT, Daugherty PS. Protease specificity determination by using cellular libraries of peptide substrates (CLiPS). Proceedings of the National Academy of Sciences of the United States of America. 103: 7583-8. PMID 16672368 DOI: 10.1073/Pnas.0511108103  0.833
2006 Rice JJ, Schohn A, Bessette PH, Boulware KT, Daugherty PS. Bacterial display using circularly permuted outer membrane protein OmpX yields high affinity peptide ligands. Protein Science : a Publication of the Protein Society. 15: 825-36. PMID 16600968 DOI: 10.1110/Ps.051897806  0.835
2006 Dane KY, Chan LA, Rice JJ, Daugherty PS. Isolation of cell specific peptide ligands using fluorescent bacterial display libraries. Journal of Immunological Methods. 309: 120-9. PMID 16448666 DOI: 10.1016/J.Jim.2005.11.021  0.837
2006 Oh SH, Lee SH, Kenrick SA, Daugherty PS, Soh HT. Cell-based protein sensor array using genetically engineered microbes Proceedings of the Ieee International Conference On Micro Electro Mechanical Systems (Mems). 2006: 486-489.  0.749
2006 Oh SH, Singh AK, Bessette PH, Kenrick SA, Rice JJ, Qian J, Daugherty PS, Soh HT. Screening of molecular libraries using the continuous-flow, micro-magnetic cell sorter Micro Total Analysis Systems - Proceedings of Microtas 2006 Conference: 10th International Conference On Miniaturized Systems For Chemistry and Life Sciences. 975-977.  0.777
2005 Curnow P, Bessette PH, Kisailus D, Murr MM, Daugherty PS, Morse DE. Enzymatic synthesis of layered titanium phosphates at low temperature and neutral pH by cell-surface display of silicatein-alpha. Journal of the American Chemical Society. 127: 15749-55. PMID 16277517 DOI: 10.1021/Ja054307F  0.341
2005 Mena MA, Daugherty PS. Automated design of degenerate codon libraries. Protein Engineering, Design & Selection : Peds. 18: 559-61. PMID 16239261 DOI: 10.1093/Protein/Gzi061  0.629
2005 Hu X, Bessette PH, Qian J, Meinhart CD, Daugherty PS, Soh HT. Marker-specific sorting of rare cells using dielectrophoresis. Proceedings of the National Academy of Sciences of the United States of America. 102: 15757-61. PMID 16236724 DOI: 10.1073/Pnas.0507719102  0.353
2005 Nguyen AW, Daugherty PS. Evolutionary optimization of fluorescent proteins for intracellular FRET. Nature Biotechnology. 23: 355-60. PMID 15696158 DOI: 10.1038/Nbt1066  0.738
2005 Dane KY, Rice JJ, Daugherty PS. Isolation of tumor targeting peptides using fluorescent bacterial display libraries Aiche Annual Meeting, Conference Proceedings. 9133.  0.832
2005 Rice JJ, Schohn A, Daugherty PS. Engineering of high affinity binding peptides using N-terminal bacterial display Aiche Annual Meeting, Conference Proceedings. 8062.  0.731
2005 Boulware KT, Daugherty PS. Bacterial substrate display: A new method for profiling protease activity Aiche Annual Meeting, Conference Proceedings. 9268.  0.842
2005 Mena MA, Bessette PH, Dane KY, Daugherty PS. Blue fluorescent protein variants with enhanced brightness from a computationally designed library Aiche Annual Meeting, Conference Proceedings. 8712.  0.736
2005 Oh SH, Wood DK, Lee SH, Dane KY, Daugherty PS, Soh HT, Cleland AN. Micromachined broadband RF cytometer for high-throughput analysis of mammalian cells Micro Total Analysis Systems - Proceedings of Microtas 2005 Conference: 9th International Conference On Miniaturized Systems For Chemistry and Life Sciences. 1: 1507-1509.  0.738
2004 Bessette PH, Rice JJ, Daugherty PS. Rapid isolation of high-affinity protein binding peptides using bacterial display. Protein Engineering, Design & Selection : Peds. 17: 731-9. PMID 15531628 DOI: 10.1093/Protein/Gzh084  0.753
2004 Bessette PH, Daugherty PS. Flow cytometric screening of cDNA expression libraries for fluorescent proteins. Biotechnology Progress. 20: 963-7. PMID 15176905 DOI: 10.1021/Bp034308G  0.363
2003 Nguyen AW, Daugherty PS. Production of randomly mutated plasmid libraries using mutator strains. Methods in Molecular Biology (Clifton, N.J.). 231: 39-44. PMID 12824600 DOI: 10.1385/1-59259-395-X:39  0.684
2003 Bessette PH, Mena MA, Nguyen AW, Daugherty PS. Construction of designed protein libraries using gene assembly mutagenesis. Methods in Molecular Biology (Clifton, N.J.). 231: 29-37. PMID 12824599 DOI: 10.1385/1-59259-395-X:29  0.764
2000 Olsen MJ, Stephens D, Griffiths D, Daugherty P, Georgiou G, Iverson BL. Function-based isolation of novel enzymes from a large library. Nature Biotechnology. 18: 1071-4. PMID 11017045 DOI: 10.1038/80267  0.475
2000 Daugherty PS, Chen G, Iverson BL, Georgiou G. Quantitative analysis of the effect of the mutation frequency on the affinity maturation of single chain Fv antibodies. Proceedings of the National Academy of Sciences of the United States of America. 97: 2029-34. PMID 10688877 DOI: 10.1073/Pnas.030527597  0.356
1999 Daugherty PS, Olsen MJ, Iverson BL, Georgiou G. Development of an optimized expression system for the screening of antibody libraries displayed on the Escherichia coli surface. Protein Engineering. 12: 613-21. PMID 10436088 DOI: 10.1093/Protein/12.7.613  0.375
1998 Daugherty PS, Chen G, Olsen MJ, Iverson BL, Georgiou G. Antibody affinity maturation using bacterial surface display. Protein Engineering. 11: 825-32. PMID 9796833 DOI: 10.1093/Protein/11.9.825  0.406
1997 Georgiou G, Stathopoulos C, Daugherty PS, Nayak AR, Iverson BL, Curtiss R. Display of heterologous proteins on the surface of microorganisms: from the screening of combinatorial libraries to live recombinant vaccines. Nature Biotechnology. 15: 29-34. PMID 9035102 DOI: 10.1038/Nbt0197-29  0.387
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