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Matthew P. Morrow, Ph.D. - Publications

Affiliations: 
2007 The George Washington University, Washington, DC, United States 
Area:
Virology, Molecular Biology
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60 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Edupuganti S, C De Rosa S, Elizaga M, Lu Y, Han X, Huang Y, Swann E, Polakowski L, A Kalams S, Keefer M, Maenza J, C Wise M, Yan J, Morrow MP, Khan AS, et al. Intramuscular and Intradermal Electroporation of HIV-1 PENNVAX-GP DNA Vaccine and IL-12 Is Safe, Tolerable, Acceptable in Healthy Adults. Vaccines. 8. PMID 33297341 DOI: 10.3390/vaccines8040741  0.312
2020 DeRosa S, Edupuganti S, Huang Y, Han X, Elizaga M, Swann E, Polakowski L, Kalams SA, Keefer MC, Maenza J, Lu Y, Wise MC, Yan J, Morrow MP, Khan AS, et al. Robust antibody and cellular responses induced by DNA-only vaccination for HIV. Jci Insight. PMID 32437332 DOI: 10.1172/Jci.Insight.137079  0.476
2020 Aggarwal C, Cohen RB, Morrow MP, Kraynyak KA, Sylvester AJ, Cheung J, Dickerson K, Schulten V, Knoblock D, Gillespie E, Bauml JM, Yan J, Diehl M, Boyer J, Dallas M, et al. Immune Therapy Targeting E6/E7 Oncogenes of Human Paillomavirus Type 6 (HPV-6) Reduces or Eliminates the Need for Surgical Intervention in the Treatment of HPV-6 Associated Recurrent Respiratory Papillomatosis. Vaccines. 8. PMID 32013270 DOI: 10.3390/Vaccines8010056  0.302
2019 Tebas P, Kraynyak KA, Patel A, Maslow JN, Morrow MP, Sylvester AJ, Knoblock D, Gillespie E, Amante D, Racine T, McMullan T, Jeong M, Roberts CC, Park YK, Boyer J, et al. Intradermal SynCon® Ebola GP DNA Vaccine is Temperature Stable and Safely Demonstrates Cellular and Humoral Immunogenicity Advantages in Healthy Volunteers. The Journal of Infectious Diseases. PMID 30891607 DOI: 10.1093/Infdis/Jiz132  0.312
2019 Reardon D, Nagpal S, Soltys S, Brem S, Omuro A, Fuente MDL, Bredlau A, Lowy I, Fury M, Morrow M, Kraynyak K, McMullan T, Santo AL, Sacchetta B, Skolnik J. Abstract CT114: INO-5401 and INO-9012 delivered by electroporation (EP) in combination with cemiplimab (REGN2810) in newly-diagnosed glioblastoma (GBM) (NCT03491683) Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-Ct114  0.31
2017 Yan J, Morrow MP, Chu JS, Racine T, Reed CC, Khan AS, Broderick KE, Kim JJ, Kobinger GP, Sardesai NY, Weiner DB. Broad cross-protective anti-hemagglutination responses elicited by influenza microconsensus DNA vaccine. Vaccine. PMID 29100705 DOI: 10.1016/J.Vaccine.2017.09.086  0.333
2017 Smith TRF, Schultheis K, Morrow MP, Kraynyak KA, McCoy JR, Yim KC, Muthumani K, Humeau L, Weiner DB, Sardesai NY, Broderick KE. Development of an intradermal DNA vaccine delivery strategy to achieve single-dose immunity against respiratory syncytial virus. Vaccine. PMID 28413132 DOI: 10.1016/J.Vaccine.2017.04.008  0.342
2016 Muthumani K, Griffin BD, Agarwal S, Kudchodkar SB, Reuschel EL, Choi H, Kraynyak KA, Duperret EK, Keaton AA, Chung C, Kim YK, Booth SA, Racine T, Yan J, Morrow MP, et al. In vivo protection against ZIKV infection and pathogenesis through passive antibody transfer and active immunisation with a prMEnv DNA vaccine. Npj Vaccines. 1: 16021. PMID 29263859 DOI: 10.1038/npjvaccines.2016.21  0.314
2016 Morrow MP, Kraynyak KA, Sylvester AJ, Shen X, Amante D, Sakata L, Parker L, Yan J, Boyer J, Roh C, Humeau L, Khan AS, Broderick K, Marcozzi-Pierce K, Giffear M, et al. Augmentation of cellular and humoral immune responses to HPV16 and HPV18 E6 and E7 antigens by VGX-3100. Molecular Therapy Oncolytics. 3: 16025. PMID 28054033 DOI: 10.1038/Mto.2016.25  0.325
2016 Wise MC, Duperret EK, Villarreal DO, Louis L, Yan J, Morrow MP, Humeau LM, Sardesai NY, Weiner DB. Abstract A020: A novel synthetic CD40L plasmid adjuvant generates unique anti-HPV DNA vaccine induced responses that impact tumor growth Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-A020  0.356
2016 Ferraro B, Walters JN, Reuschel EL, Balakrishnan A, Morrow MP, Khan AS, Sardesai NY, Humeau LM, Weiner DB. Abstract LB-253: Control of tumor growth in vivo by a synthetic multi-antigen DNA immune therapy for prostate cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-253  0.319
2016 Wise M, Villarreal D, Louis L, Yan J, Morrow M, Sardesai N, Weiner D. 643. Various Forms of CD40L Encoded as an Immune Plasmid Adjuvant Generate Unique Anti-Cancer DNA Vaccine Induced Responses Molecular Therapy. 24: S255. DOI: 10.1016/S1525-0016(16)33451-7  0.363
2016 Morrow M, Trimble C, Shen X, Dallas M, Weiner D, Boyer J, Yan J, Kraynyak K, Sylester A, Giffear M, Marcozzi-Pierce K, Shah D, Broderick K, Khan A, Lee J, et al. 505. VGX-3100 Drives Regression of HPV16/18 CIN2/3 and Robust Cellular Immune Responses in Blood and Cervical Tissue in a Blinded, Randomized, Placebo-Controlled Phase 2B Study Molecular Therapy. 24: S201. DOI: 10.1016/S1525-0016(16)33314-7  0.321
2016 Wise M, Muthumani K, Mendoza J, Yan J, Slager A, Kraynyak K, Montefiori D, LaBranche C, Broderick K, Morrow M, Sardesai N, Weiner D. 440. Extreme Polyvalency Induces Potent Cross-Clade Cellular and Humoral Responses in Rabbits and Non-Human Primates Molecular Therapy. 24: S174. DOI: 10.1016/S1525-0016(16)33249-X  0.373
2015 Muthumani K, Falzarano D, Reuschel EL, Tingey C, Flingai S, Villarreal DO, Wise M, Patel A, Izmirly A, Aljuaid A, Seliga AM, Soule G, Morrow M, Kraynyak KA, Khan AS, et al. A synthetic consensus anti-spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primates. Science Translational Medicine. 7: 301ra132. PMID 26290414 DOI: 10.1016/J.Ijid.2016.02.083  0.374
2015 Villarreal DO, Svoronos N, Wise MC, Shedlock DJ, Morrow MP, Conejo-Garcia JR, Weiner DB. Molecular adjuvant IL-33 enhances the potency of a DNA vaccine in a lethal challenge model. Vaccine. PMID 25887087 DOI: 10.1016/J.Vaccine.2015.03.086  0.358
2015 Carnathan DG, Wetzel KS, Yu J, Lee ST, Johnson BA, Paiardini M, Yan J, Morrow MP, Sardesai NY, Weiner DB, Ertl HC, Silvestri G. Activated CD4+CCR5+ T cells in the rectum predict increased SIV acquisition in SIVGag/Tat-vaccinated rhesus macaques. Proceedings of the National Academy of Sciences of the United States of America. 112: 518-23. PMID 25550504 DOI: 10.1073/Pnas.1407466112  0.421
2015 Morrow MP, Tebas P, Yan J, Ramirez L, Slager A, Kraynyak K, Diehl M, Shah D, Khan A, Lee J, Boyer J, Kim JJ, Sardesai NY, Weiner DB, Bagarazzi ML. Synthetic consensus HIV-1 DNA induces potent cellular immune responses and synthesis of granzyme B, perforin in HIV infected individuals. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 591-601. PMID 25531694 DOI: 10.1038/Mt.2014.245  0.502
2015 Vonderheide RH, Aggarwal C, Bajor DL, Goldenberg J, Loch C, Lee JC, Yan J, Morrow MP, DeMichele A, Langer CJ, O'Dwyer PJ, Weiner DB, Yang Z, Bagarazzi ML. Study of hTERT and IL-12 DNA immunotherapy using electroporation in patients with solid tumors after definitive surgery and adjuvant therapy. Journal of Clinical Oncology. 33: TPS3104-TPS3104. DOI: 10.1200/Jco.2015.33.15_Suppl.Tps3104  0.328
2015 Morrow M, Trimble C, Shen X, Dallas M, Weiner D, Boyer J, Yan J, Kraynyak K, Sylvester A, Giffear M, Marcozzi-Pierce K, Shah D, Broderick K, Khan A, Lee J, et al. Abstract CT131: HPV specific immunotherapy for cervical intraepithelial neoplasia using VGX-3100 induces regression of cervical lesions and potent T-cell responses: Results from a randomized, double-blind, placebo-controlled phase II study Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Ct131  0.315
2015 Ferraro B, Walters JN, Reuschel EL, Balakrishnan A, Morrow MP, Yan J, Khan AS, Sardesai NY, Humeau LM, Weiner DB. 210. Complete Control of Tumor Growth In Vivo By a Synthetic Consensus Multi-Antigen DNA Immune Therapy for Prostate Cancer Molecular Therapy. 23: S83. DOI: 10.1016/S1525-0016(16)33815-1  0.329
2014 Latimer B, Toporovski R, Yan J, Pankhong P, Morrow MP, Khan AS, Sardesai NY, Welles SL, Jacobson JM, Weiner DB, Kutzler MA. Strong HCV NS3/4a, NS4b, NS5a, NS5b-specific cellular immune responses induced in Rhesus macaques by a novel HCV genotype 1a/1b consensus DNA vaccine. Human Vaccines & Immunotherapeutics. 10: 2357-65. PMID 25424943 DOI: 10.4161/Hv.29590  0.318
2014 Yan J, Villarreal DO, Racine T, Chu JS, Walters JN, Morrow MP, Khan AS, Sardesai NY, Kim JJ, Kobinger GP, Weiner DB. Protective immunity to H7N9 influenza viruses elicited by synthetic DNA vaccine. Vaccine. 32: 2833-42. PMID 24631084 DOI: 10.1016/J.Vaccine.2014.02.038  0.356
2014 Maldonado L, Teague JE, Morrow MP, Jotova I, Wu TC, Wang C, Desmarais C, Boyer JD, Tycko B, Robins HS, Clark RA, Trimble CL. Intramuscular therapeutic vaccination targeting HPV16 induces T cell responses that localize in mucosal lesions. Science Translational Medicine. 6: 221ra13. PMID 24477000 DOI: 10.1126/Scitranslmed.3007323  0.34
2014 Villarreal DO, Wise MC, Walters JN, Reuschel EL, Choi MJ, Obeng-Adjei N, Yan J, Morrow MP, Weiner DB. Alarmin IL-33 acts as an immunoadjuvant to enhance antigen-specific tumor immunity. Cancer Research. 74: 1789-800. PMID 24448242 DOI: 10.1158/0008-5472.Can-13-2729  0.334
2014 Morrow MP, Kraynyak K, Shen X, Knott C, Yan J, Broderick K, Khan A, Giffear M, Lee J, Boyer J, Weiner D, Sardesai N, Bagarazzi M. Boosting of cellular and humoral immune responses to HPV16/18 antigens by VGX-3100: A follow-on phase I trial. Journal of Clinical Oncology. 32: 3101-3101. DOI: 10.1200/Jco.2014.32.15_Suppl.3101  0.336
2014 Villarreal D, Wise M, Walters J, Yan J, Morrow MP, Bagarazzi M, Sardesai N, Weiner D. Synthetic IL-33 DNA as anti-tumor adjuvant in vivo. Journal of Clinical Oncology. 32: 3098-3098. DOI: 10.1200/Jco.2014.32.15_Suppl.3098  0.367
2014 Villarreal DO, Svoronos N, Wise MC, Walters JN, Morrow M, Weiner DB. 192 Cytokine. 70: 74. DOI: 10.1016/J.Cyto.2014.07.199  0.364
2013 Yan J, Pankhong P, Shin TH, Obeng-Adjei N, Morrow MP, Walters JN, Khan AS, Sardesai NY, Weiner DB. Highly optimized DNA vaccine targeting human telomerase reverse transcriptase stimulates potent antitumor immunity. Cancer Immunology Research. 1: 179-89. PMID 24777680 DOI: 10.1158/2326-6066.Cir-13-0001  0.368
2013 Obeng-Adjei N, Hutnick NA, Yan J, Chu JS, Myles DJ, Morrow MP, Sardesai NY, Weiner DB. DNA vaccine cocktail expressing genotype A and C HBV surface and consensus core antigens generates robust cytotoxic and antibody responses in mice and Rhesus macaques. Cancer Gene Therapy. 20: 652-62. PMID 24310062 DOI: 10.1038/Cgt.2013.65  0.375
2013 Ferraro B, Talbott KT, Balakrishnan A, Cisper N, Morrow MP, Hutnick NA, Myles DJ, Shedlock DJ, Obeng-Adjei N, Yan J, Kayatani AK, Richie N, Cabrera W, Shiver R, Khan AS, et al. Inducing humoral and cellular responses to multiple sporozoite and liver-stage malaria antigens using exogenous plasmid DNA. Infection and Immunity. 81: 3709-20. PMID 23897618 DOI: 10.1128/Iai.00180-13  0.33
2013 Morrow MP, Yan J, Sardesai NY. Human papillomavirus therapeutic vaccines: targeting viral antigens as immunotherapy for precancerous disease and cancer. Expert Review of Vaccines. 12: 271-83. PMID 23496667 DOI: 10.1586/Erv.13.23  0.367
2012 Bagarazzi ML, Yan J, Morrow MP, Shen X, Parker RL, Lee JC, Giffear M, Pankhong P, Khan AS, Broderick KE, Knott C, Lin F, Boyer JD, Draghia-Akli R, White CJ, et al. Immunotherapy against HPV16/18 generates potent TH1 and cytotoxic cellular immune responses. Science Translational Medicine. 4: 155ra138. PMID 23052295 DOI: 10.1126/Scitranslmed.3004414  0.324
2012 Hutnick N, Karuppiah M, Pollara J, Yan J, Myles D, Broderick K, Morrow M, Sardasai N, Montefiori D, Barnett S, Ferrari G, Weiner D. E-DNA IM or ID delivery prime enhances antibody and T cell responses following recombinant gp120 env boost Retrovirology. 9: 364. DOI: 10.1186/1742-4690-9-S2-P364  0.396
2012 Tebas P, Ramirez L, Morrow M, Yan J, Shah D, Lee J, Weiner D, Boyer J, Bagarazzi M, Sardesai N. Potent cellular immune responses after therapeutic immunization of HIV-positive patients with the PENNVAX®-B DNA vaccine in a Phase I Trial. Retrovirology. 9: 276. DOI: 10.1186/1742-4690-9-S2-P276  0.531
2012 Hutnick N, Myles D, Muthumani K, Morrow M, Yan J, Khan A, Sardasai N, Weiner D. Robust antibody and cellular responses with an improved DNA vaccine alone Retrovirology. 9: 15. DOI: 10.1186/1742-4690-9-S2-P15  0.43
2011 Hirao LA, Hokey DA, Morrow MP, Jure-Kunkel MN, Weiner DB. Immune modulation through 4-1BB enhances SIV vaccine protection in non-human primates against SIVmac251 challenge. Plos One. 6: e24250. PMID 21935390 DOI: 10.1371/Journal.Pone.0024250  0.428
2011 Ferraro B, Morrow MP, Hutnick NA, Shin TH, Lucke CE, Weiner DB. Clinical applications of DNA vaccines: current progress. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 53: 296-302. PMID 21765081 DOI: 10.1093/Cid/Cir334  0.324
2011 Fagone P, Shedlock DJ, Bao H, Kawalekar OU, Yan J, Gupta D, Morrow MP, Patel A, Kobinger GP, Muthumani K, Weiner DB. Molecular adjuvant HMGB1 enhances anti-influenza immunity during DNA vaccination. Gene Therapy. 18: 1070-7. PMID 21544096 DOI: 10.1038/Gt.2011.59  0.328
2011 Shedlock DJ, Talbott KT, Cress C, Ferraro B, Tuyishme S, Mallilankaraman K, Cisper NJ, Morrow MP, Wu SJ, Kawalekar OU, Khan AS, Sardesai NY, Muthumani K, Shen H, Weiner DB. A highly optimized DNA vaccine confers complete protective immunity against high-dose lethal lymphocytic choriomeningitis virus challenge. Vaccine. 29: 6755-62. PMID 21238574 DOI: 10.1016/J.Vaccine.2010.12.064  0.371
2011 Broderick KE, Shen X, Soderholm J, Lin F, McCoy J, Khan AS, Yan J, Morrow MP, Patel A, Kobinger GP, Kemmerrer S, Weiner DB, Sardesai NY. Prototype development and preclinical immunogenicity analysis of a novel minimally invasive electroporation device. Gene Therapy. 18: 258-65. PMID 20962869 DOI: 10.1038/Gt.2010.137  0.311
2011 Khan AS, Broderick KE, Yan J, Morrow MP, Sardesai NY. Safe and Effective Smallpox Vaccine Development Using DNA Vaccines and In vivo Electroporation,Probabilistic risk assessment Journal of Bioterrorism and Biodefense. 2012. DOI: 10.4172/2157-2526.S1-010  0.317
2010 Toporovski R, Morrow MP, Weiner DB. Interferons as potential adjuvants in prophylactic vaccines. Expert Opinion On Biological Therapy. 10: 1489-500. PMID 20836750 DOI: 10.1517/14712598.2010.521495  0.326
2010 Morrow MP, Yan J, Pankhong P, Ferraro B, Lewis MG, Khan AS, Sardesai NY, Weiner DB. Unique Th1/Th2 phenotypes induced during priming and memory phases by use of interleukin-12 (IL-12) or IL-28B vaccine adjuvants in rhesus macaques. Clinical and Vaccine Immunology : Cvi. 17: 1493-9. PMID 20685940 DOI: 10.1128/Cvi.00181-10  0.31
2010 Asztalos BF, Mujawar Z, Morrow MP, Grant A, Pushkarsky T, Wanke C, Shannon R, Geyer M, Kirchhoff F, Sviridov D, Fitzgerald ML, Bukrinsky M, Mansfield KG. Circulating Nef induces dyslipidemia in simian immunodeficiency virus-infected macaques by suppressing cholesterol efflux. The Journal of Infectious Diseases. 202: 614-23. PMID 20617930 DOI: 10.1086/654817  0.755
2010 Morrow MP, Yan J, Pankhong P, Shedlock DJ, Lewis MG, Talbott K, Toporovski R, Khan AS, Sardesai NY, Weiner DB. IL-28B/IFN-lambda 3 drives granzyme B loading and significantly increases CTL killing activity in macaques. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1714-23. PMID 20571540 DOI: 10.1038/Mt.2010.118  0.306
2010 Morrow MP, Grant A, Mujawar Z, Dubrovsky L, Pushkarsky T, Kiselyeva Y, Jennelle L, Mukhamedova N, Remaley AT, Kashanchi F, Sviridov D, Bukrinsky M. Stimulation of the liver X receptor pathway inhibits HIV-1 replication via induction of ATP-binding cassette transporter A1. Molecular Pharmacology. 78: 215-25. PMID 20479131 DOI: 10.1124/Mol.110.065029  0.71
2010 Shedlock DJ, Talbott KT, Morrow MP, Ferraro B, Hokey DA, Muthumani K, Weiner DB. Ki-67 staining for determination of rhesus macaque T cell proliferative responses ex vivo. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 77: 275-84. PMID 20104580 DOI: 10.1002/Cyto.A.20857  0.344
2010 Valentin A, Morrow M, Poirier RH, Aleman K, Little R, Yarchoan R, Pavlakis GN. Identification of a potential pharmacological sanctuary for HIV type 1 in a fraction of CD4(+) primary cells. Aids Research and Human Retroviruses. 26: 79-88. PMID 20059395 DOI: 10.1089/aid.2009.0044  0.312
2009 Kraynyak KA, Kutzler MA, Cisper NJ, Laddy DJ, Morrow MP, Waldmann TA, Weiner DB. Plasmid-encoded interleukin-15 receptor alpha enhances specific immune responses induced by a DNA vaccine in vivo. Human Gene Therapy. 20: 1143-56. PMID 19530914 DOI: 10.1089/Hum.2009.025  0.334
2009 Morrow MP, Pankhong P, Laddy DJ, Schoenly KA, Yan J, Cisper N, Weiner DB. Comparative ability of IL-12 and IL-28B to regulate Treg populations and enhance adaptive cellular immunity. Blood. 113: 5868-77. PMID 19304955 DOI: 10.1182/Blood-2008-11-190520  0.31
2009 Thieu KP, Morrow MP, Shedlock DJ, Schoenly KA, Mallilankaraman K, Choo AY, Fagone P, Weiner DB, Muthumani K. HIV-1 Vpr: regulator of viral survival. Current Hiv Research. 7: 153-62. PMID 19275584 DOI: 10.2174/157016209787581454  0.528
2009 Yan J, Hokey DA, Morrow MP, Corbitt N, Harris K, Harris D, Weiner DB. Novel SIVmac DNA vaccines encoding Env, Pol and Gag consensus proteins elicit strong cellular immune responses in cynomolgus macaques. Vaccine. 27: 3260-6. PMID 19200811 DOI: 10.1016/J.Vaccine.2009.01.065  0.457
2009 Morrow M, Yan J, Pankhong P, Harris K, Kahn A, Sardesai N, Weiner D. P02-02. Analysis of antigen specific degranulation potentials using IL-12 or IL-28B during HIV DNA Vaccination Retrovirology. 6: P7. DOI: 10.1186/1742-4690-6-S3-P7  0.431
2008 Morrow MP, Weiner DB. Cytokines as adjuvants for improving anti-HIV responses. Aids (London, England). 22: 333-8. PMID 18195559 DOI: 10.1097/Qad.0B013E3282F42461  0.459
2006 Mujawar Z, Rose H, Morrow MP, Pushkarsky T, Dubrovsky L, Mukhamedova N, Fu Y, Dart A, Orenstein JM, Bobryshev YV, Bukrinsky M, Sviridov D. Human immunodeficiency virus impairs reverse cholesterol transport from macrophages. Plos Biology. 4: e365. PMID 17076584 DOI: 10.1186/1742-4690-3-S1-S82  0.788
2006 Bukrinsky M, D'Eustachio P, Gillespie M, Gopinathrao G, Iordanskiy S, Morrow M, Matthews L, Rice A. HIV Life Cycle Reactome - a Curated Knowledgebase of Biological Pathways. 18. DOI: 10.3180/React_6256.3  0.62
2006 Morrow MP, Mujawar ZA, Bukrinsky MI. Anti-HIV activity of drugs that stimulate cholesterol efflux Retrovirology. 3. DOI: 10.1186/1742-4690-3-S1-P42  0.703
2006 Bukrinsky M, Mujawar Z, Morrow M, Orenstein J, Bobryshev Y, Sviridov D. Th-P15:233 Human immunodeficiency virus impairs reverse cholesterol transport from macrophages Atherosclerosis Supplements. 7: 544. DOI: 10.1016/S1567-5688(06)82192-6  0.74
2005 Mujawar Z, Rose H, Morrow MP, Orenstein J, Bobryshev Y, Sviridov D, Bukrinsky M. Retrovirology. 2: S151. DOI: 10.1186/1742-4690-2-S1-S151  0.782
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