Andrew Holmes - Publications

National Institute on Alcohol Abuse and Alcoholism, North Bethesda, MD, United States 

154 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Gunduz-Cinar O, Brockway ET, Castillo LI, Pollack GA, Erguven T, Holmes A. Selective sub-nucleus effects of intra-amygdala oxytocin on fear extinction. Behavioural Brain Research. 112798. PMID 32653556 DOI: 10.1016/j.bbr.2020.112798  0.56
2020 Glover LR, Postle AF, Holmes A. Touchscreen-based assessment of risky-choice in mice. Behavioural Brain Research. 112748. PMID 32531231 DOI: 10.1016/j.bbr.2020.112748  0.72
2020 Mock ED, Mustafa M, Gunduz-Cinar O, Cinar R, Petrie GN, Kantae V, Di X, Ogasawara D, Varga ZV, Paloczi J, Miliano C, Donvito G, van Esbroeck ACM, van der Gracht AMF, Kotsogianni I, ... ... Holmes A, et al. Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice. Nature Chemical Biology. PMID 32393901 DOI: 10.1038/s41589-020-0528-7  0.32
2019 Halladay LR, Kocharian A, Piantadosi PT, Authement ME, Lieberman AG, Spitz NA, Coden K, Glover LR, Costa VD, Alvarez VA, Holmes A. Prefrontal Regulation of Punished Ethanol Self-administration. Biological Psychiatry. PMID 31937415 DOI: 10.1016/j.biopsych.2019.10.030  0.72
2019 Rovira-Esteban L, Gunduz-Cinar O, Bukalo O, Limoges A, Brockway E, Müller K, Fenno L, Kim YS, Ramakrishnan C, Andrási T, Deisseroth K, Holmes A, Hájos N. Excitation of diverse classes of cholecystokinin interneurons in the basolateral amygdala facilitates fear extinction. Eneuro. PMID 31636080 DOI: 10.1523/ENEURO.0220-19.2019  1
2019 Delgado-Acevedo C, Estay SF, Radke AK, Sengupta A, Escobar AP, Henríquez-Belmar F, Reyes CA, Haro-Acuña V, Utreras E, Sotomayor-Zárate R, Cho A, Wendland JR, Kulkarni AB, Holmes A, Murphy DL, et al. Correction: Behavioral and synaptic alterations relevant to obsessivecompulsive disorder in mice with increased EAAT3 expression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30787427 DOI: 10.1038/s41386-019-0331-x  0.68
2019 Marquardt K, Josey M, Kenton JA, Cavanagh JF, Holmes A, Brigman JL. Impaired cognitive flexibility following NMDAR-GluN2B deletion is associated with altered orbitofrontal-striatal function. Neuroscience. PMID 30742964 DOI: 10.1016/j.neuroscience.2019.01.066  0.68
2019 Radke AK, Zweifel LS, Holmes A. NMDA receptor deletion on dopamine neurons disrupts visual discrimination and reversal learning. Neuroscience Letters. 699: 109-114. PMID 30726715 DOI: 10.1016/j.neulet.2019.02.001  0.68
2019 Ferrazzo S, Gunduz-Cinar O, Stefanova N, Pollack GA, Holmes A, Schmuckermair C, Ferraguti F. Increased anxiety-like behavior following circuit-specific catecholamine denervation in mice. Neurobiology of Disease. 125: 55-66. PMID 30677495 DOI: 10.1016/j.nbd.2019.01.009  0.56
2019 Piantadosi PT, Lieberman AG, Pickens CL, Bergstrom HC, Holmes A. A novel multichoice touchscreen paradigm for assessing cognitive flexibility in mice. Learning & Memory (Cold Spring Harbor, N.Y.). 26: 24-30. PMID 30559117 DOI: 10.1101/lm.048264.118  0.56
2018 Delgado-Acevedo C, Estay SF, Radke A, Sengupta A, Escobar AP, Henríquez-Belmar F, Reyes C, Haro V, Utreras E, Sotomayor-Zárate R, Cho A, Wendland JR, Kulkarni AB, Holmes A, Murphy DL, et al. Behavioral and synaptic alterations relevant to obsessive-compulsive disorder in mice with increased EAAT3 expression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30622300 DOI: 10.1038/s41386-018-0302-7  0.4
2018 Kenton JA, Castillo R, Holmes A, Brigman JL. Cortico-hippocampal GluN2B is essential for efficient visual-spatial discrimination learning in a touchscreen paradigm. Neurobiology of Learning and Memory. 156: 60-67. PMID 30394331 DOI: 10.1016/j.nlm.2018.10.011  0.68
2018 Singewald N, Holmes A. Rodent models of impaired fear extinction. Psychopharmacology. PMID 30377749 DOI: 10.1007/s00213-018-5054-x  0.32
2018 Radke AK, Kocharian A, Covey DP, Lovinger DM, Cheer JF, Mateo Y, Holmes A. Contributions of nucleus accumbens dopamine to cognitive flexibility. The European Journal of Neuroscience. PMID 30218623 DOI: 10.1111/ejn.14152  0.68
2018 O'Connor RM, McCafferty CP, Bravo JA, Singewald N, Holmes A, Cryan JF. Increased amygdalar metabotropic glutamate receptor 7 mRNA in a genetic mouse model of impaired fear extinction. Psychopharmacology. PMID 30215216 DOI: 10.1007/s00213-018-5031-4  0.32
2018 Lowery-Gionta EG, Crowley NA, Bukalo O, Silverstein S, Holmes A, Kash TL. Chronic stress dysregulates amygdalar output to the prefrontal cortex. Neuropharmacology. PMID 29959957 DOI: 10.1016/j.neuropharm.2018.06.032  1
2018 Jury NJ, Radke AK, Pati D, Kocharian A, Mishina M, Kash TL, Holmes A. NMDA receptor GluN2A subunit deletion protects against dependence-like ethanol drinking. Behavioural Brain Research. PMID 29953905 DOI: 10.1016/j.bbr.2018.06.029  0.68
2018 Bergstrom HC, Lipkin AM, Lieberman AG, Pinard CR, Gunduz-Cinar O, Brockway ET, Taylor WW, Nonaka M, Bukalo O, Wills TA, Rubio FJ, Li X, Pickens CL, Winder DG, Holmes A. Dorsolateral Striatum Engagement Interferes with Early Discrimination Learning. Cell Reports. 23: 2264-2272. PMID 29791838 DOI: 10.1016/j.celrep.2018.04.081  1
2018 Bukalo O, Holmes A. Everything in Its Right Place: A Prefrontal-Midbrain Circuit for Contextual Fear Discrimination. Neuron. 97: 732-733. PMID 29470964 DOI: 10.1016/j.neuron.2018.02.011  1
2018 Gunduz-Cinar O, Brockway E, Lederle L, Wilcox T, Halladay LR, Ding Y, Oh H, Busch EF, Kaugars K, Flynn S, Limoges A, Bukalo O, MacPherson KP, Masneuf S, Pinard C, ... ... Holmes A, et al. Identification of a novel gene regulating amygdala-mediated fear extinction. Molecular Psychiatry. PMID 29311651 DOI: 10.1038/s41380-017-0003-3  1
2017 Jury NJ, Pollack GA, Ward MJ, Bezek JL, Ng AJ, Pinard CR, Bergstrom HC, Holmes A. Chronic Ethanol During Adolescence Impacts Corticolimbic Dendritic Spines and Behavior. Alcoholism, Clinical and Experimental Research. PMID 28614590 DOI: 10.1111/acer.13422  0.68
2017 Peterson VL, Jury NJ, Cabrera-Rubio R, Draper LA, Crispie F, Cotter PD, Dinan TG, Holmes A, Cryan JF. Drunk Bugs: Chronic Vapour Alcohol Exposure Induces Marked Changes in the Gut Microbiome in Mice. Behavioural Brain Research. PMID 28161446 DOI: 10.1016/j.bbr.2017.01.049  0.56
2017 Radke AK, Jury NJ, Delpire E, Nakazawa K, Holmes A. Reduced ethanol drinking following selective cortical interneuron deletion of the GluN2B NMDA receptors subunit. Alcohol (Fayetteville, N.Y.). 58: 47-51. PMID 28109345 DOI: 10.1016/j.alcohol.2016.07.005  0.68
2016 Williams RW, Holmes A. Preface to a special issue on genetic models of alcoholism and alcohol-stress interactions. Alcohol (Fayetteville, N.Y.). PMID 27912921 DOI: 10.1016/j.alcohol.2016.11.010  0.32
2016 Jury NJ, DiBerto JF, Kash TL, Holmes A. Sex differences in the behavioral sequelae of chronic ethanol exposure. Alcohol (Fayetteville, N.Y.). PMID 27624846 DOI: 10.1016/j.alcohol.2016.07.007  0.56
2016 Izquierdo A, Brigman JL, Radke AK, Rudebeck PH, Holmes A. The neural basis of reversal learning: An updated perspective. Neuroscience. PMID 26979052 DOI: 10.1016/j.neuroscience.2016.03.021  0.68
2016 Didion JP, Morgan AP, Yadgary L, Bell TA, McMullan RC, Ortiz de Solorzano L, Britton-Davidian J, Bult CJ, Campbell KJ, Castiglia R, Ching YH, Chunco AJ, Crowley JJ, Chesler EJ, Förster DW, ... ... Holmes A, et al. R2d2 drives selfish sweeps in the house mouse. Molecular Biology and Evolution. PMID 26882987 DOI: 10.1093/molbev/msw036  0.8
2015 Radke AK, Jury NJ, Kocharian A, Marcinkiewcz CA, Lowery-Gionta EG, Pleil KE, McElligott ZA, McKlveen JM, Kash TL, Holmes A. Chronic EtOH effects on putative measures of compulsive behavior in mice. Addiction Biology. PMID 26687341 DOI: 10.1111/adb.12342  0.68
2015 Piccart-Gebhart M, Holmes E, Baselga J, de Azambuja E, Dueck AC, Viale G, Zujewski JA, Goldhirsch A, Armour A, Pritchard KI, McCullough AE, Dolci S, McFadden E, Holmes AP, Tonghua L, et al. Adjuvant Lapatinib and Trastuzumab for Early Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer: Results From the Randomized Phase III Adjuvant Lapatinib and/or Trastuzumab Treatment Optimization Trial. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 26598744 DOI: 10.1200/JCO.2015.62.1797  0.8
2015 Gunduz-Cinar O, Flynn S, Brockway E, Kaugars K, Baldi R, Ramikie TS, Cinar R, Kunos G, Patel S, Holmes A. Fluoxetine Facilitates Fear Extinction through Amygdala Endocannabinoids. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26514583 DOI: 10.1038/npp.2015.318  0.8
2015 Bukalo O, Pinard CR, Silverstein S, Brehm C, Hartley ND, Whittle N, Colacicco G, Busch E, Patel S, Singewald N, Holmes A. Prefrontal inputs to the amygdala instruct fear extinction memory formation. Science Advances. 1. PMID 26504902 DOI: 10.1126/sciadv.1500251  1
2015 Holmes A, Chen A. GABA receptors in a state of fear. Nature Neuroscience. 18: 1194-6. PMID 26308977 DOI: 10.1038/nn.4098  0.8
2015 Radke AK, Nakazawa K, Holmes A. Cortical GluN2B deletion attenuates punished suppression of food reward-seeking. Psychopharmacology. 232: 3753-61. PMID 26223494 DOI: 10.1007/s00213-015-4033-8  0.68
2015 Brigman JL, Daut RA, Saksida L, Bussey TJ, Nakazawa K, Holmes A. Impaired discrimination learning in interneuronal NMDAR-GluN2B mutant mice. Neuroreport. 26: 489-94. PMID 25968910 DOI: 10.1097/WNR.0000000000000373  0.68
2015 Reeson P, Tennant KA, Gerrow K, Wang J, Weiser Novak S, Thompson K, Lockhart KL, Holmes A, Nahirney PC, Brown CE. Delayed inhibition of VEGF signaling after stroke attenuates blood-brain barrier breakdown and improves functional recovery in a comorbidity-dependent manner. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 5128-43. PMID 25834040 DOI: 10.1523/JNEUROSCI.2810-14.2015  0.8
2015 Taylor SL, Trudeau D, Arnold B, Wang J, Gerrow K, Summerfeldt K, Holmes A, Zamani A, Brocardo PS, Brown CE. VEGF can protect against blood brain barrier dysfunction, dendritic spine loss and spatial memory impairment in an experimental model of diabetes. Neurobiology of Disease. 78: 1-11. PMID 25829228 DOI: 10.1016/j.nbd.2015.03.022  0.8
2015 Fitzgerald PJ, Pinard CR, Camp MC, Feyder M, Sah A, Bergstrom HC, Graybeal C, Liu Y, Schlüter OM, Grant SG, Singewald N, Xu W, Holmes A. Durable fear memories require PSD-95. Molecular Psychiatry. 20: 913. PMID 25824301 DOI: 10.1038/mp.2015.44  0.8
2015 Kiselycznyk C, Jury NJ, Halladay LR, Nakazawa K, Mishina M, Sprengel R, Grant SG, Svenningsson P, Holmes A. NMDA receptor subunits and associated signaling molecules mediating antidepressant-related effects of NMDA-GluN2B antagonism. Behavioural Brain Research. 287: 89-95. PMID 25800971 DOI: 10.1016/j.bbr.2015.03.023  0.8
2015 Thompson SM, Josey M, Holmes A, Brigman JL. Conditional loss of GluN2B in cortex and hippocampus impairs attentional set formation. Behavioral Neuroscience. 129: 105-12. PMID 25798630 DOI: 10.1037/bne0000045  0.8
2015 Holmes A. G2B Reviews: stress at the intersection of anxiety, addiction and eating disorders. Genes, Brain, and Behavior. 14: 1-3. PMID 25626482 DOI: 10.1111/gbb.12196  0.8
2015 Singewald N, Schmuckermair C, Whittle N, Holmes A, Ressler KJ. Pharmacology of cognitive enhancers for exposure-based therapy of fear, anxiety and trauma-related disorders. Pharmacology & Therapeutics. 149: 150-90. PMID 25550231 DOI: 10.1016/j.pharmthera.2014.12.004  0.8
2015 Fitzgerald PJ, Pinard CR, Camp MC, Feyder M, Sah A, Bergstrom HC, Graybeal C, Liu Y, Schlüter OM, Grant SG, Singewald N, Xu W, Holmes A. Durable fear memories require PSD-95. Molecular Psychiatry. 20: 901-12. PMID 25510511 DOI: 10.1038/mp.2014.161  0.8
2015 Piantadosi PT, Holmes A, Roberts BM, Bailey AM. Orexin receptor activity in the basal forebrain alters performance on an olfactory discrimination task. Brain Research. 1594: 215-22. PMID 25451124 DOI: 10.1016/j.brainres.2014.10.041  0.52
2015 DePoy L, Daut R, Wright T, Camp M, Crowley N, Noronha B, Lovinger D, Holmes A. Chronic alcohol alters rewarded behaviors and striatal plasticity. Addiction Biology. 20: 345-8. PMID 24666522 DOI: 10.1111/adb.12131  0.8
2015 Daut RA, Busch EF, Ihne J, Fisher D, Mishina M, Grant SG, Camp M, Holmes A. Tolerance to ethanol intoxication after chronic ethanol: role of GluN2A and PSD-95. Addiction Biology. 20: 259-62. PMID 24397780 DOI: 10.1111/adb.12110  0.8
2015 Brigman JL, Daut RA, Saksida L, Bussey TJ, Nakazawa K, Holmes A. Impaired discrimination learning in interneuronal NMDAR-GluN2B mutant mice Neuroreport. 26: 489-494. DOI: 10.1097/WNR.0000000000000373  0.8
2015 Radke AK, Nakazawa K, Holmes A. Cortical GluN2B deletion attenuates punished suppression of food reward-seeking Psychopharmacology. DOI: 10.1007/s00213-015-4033-8  0.8
2014 de Azambuja E, Holmes AP, Piccart-Gebhart M, Holmes E, Di Cosimo S, Swaby RF, Untch M, Jackisch C, Lang I, Smith I, Boyle F, Xu B, Barrios CH, Perez EA, Azim HA, et al. Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): survival outcomes of a randomised, open-label, multicentre, phase 3 trial and their association with pathological complete response. The Lancet. Oncology. 15: 1137-46. PMID 25130998 DOI: 10.1016/S1470-2045(14)70320-1  0.8
2014 Bukalo O, Pinard CR, Holmes A. Mechanisms to medicines: elucidating neural and molecular substrates of fear extinction to identify novel treatments for anxiety disorders. British Journal of Pharmacology. 171: 4690-718. PMID 24835117 DOI: 10.1111/bph.12779  0.8
2014 Masneuf S, Lowery-Gionta E, Colacicco G, Pleil KE, Li C, Crowley N, Flynn S, Holmes A, Kash T. Glutamatergic mechanisms associated with stress-induced amygdala excitability and anxiety-related behavior. Neuropharmacology. 85: 190-7. PMID 24796255 DOI: 10.1016/j.neuropharm.2014.04.015  0.8
2014 Graybeal C, Bachu M, Mozhui K, Saksida LM, Bussey TJ, Sagalyn E, Williams RW, Holmes A. Strains and stressors: an analysis of touchscreen learning in genetically diverse mouse strains. Plos One. 9: e87745. PMID 24586288 DOI: 10.1371/journal.pone.0087745  0.8
2014 Holmes A. Introducing G2B(reviews). Genes, Brain, and Behavior. 13: 1. PMID 24393254 DOI: 10.1111/gbb.12111  0.8
2014 Fitzgerald PJ, Whittle N, Flynn SM, Graybeal C, Pinard CR, Gunduz-Cinar O, Kravitz AV, Singewald N, Holmes A. Prefrontal single-unit firing associated with deficient extinction in mice. Neurobiology of Learning and Memory. 113: 69-81. PMID 24231425 DOI: 10.1016/j.nlm.2013.11.002  0.8
2014 Wellman CL, Camp M, Jones VM, MacPherson KP, Ihne J, Fitzgerald P, Maroun M, Drabant E, Bogdan R, Hariri AR, Holmes A. Corrigendum to "Convergent effects of mouse Pet-1 deletion and human PET-1 variation on amygdala fear and threat processing" [Exp. Neurol. 250 (2013) 260-269] Experimental Neurology. 252: 104. DOI: 10.1016/j.expneurol.2013.11.002  0.8
2014 Radke AK, Pickens CL, Holmes A. The Effects of Stress on Measures of Alcohol Drinking in Rodents Neurobiology of Alcohol Dependence. 97-110. DOI: 10.1016/B978-0-12-405941-2.00006-7  0.8
2013 Gunduz-Cinar O, Hill MN, McEwen BS, Holmes A. Amygdala FAAH and anandamide: mediating protection and recovery from stress. Trends in Pharmacological Sciences. 34: 637-44. PMID 24325918 DOI: 10.1016/  0.8
2013 Wellman CL, Camp M, Jones VM, MacPherson KP, Ihne J, Fitzgerald P, Maroun M, Drabant E, Bogdan R, Hariri AR, Holmes A. Convergent effects of mouse Pet-1 deletion and human PET-1 variation on amygdala fear and threat processing. Experimental Neurology. 250: 260-9. PMID 24100022 DOI: 10.1016/j.expneurol.2013.09.025  0.8
2013 Mar AC, Horner AE, Nilsson SR, Alsiö J, Kent BA, Kim CH, Holmes A, Saksida LM, Bussey TJ. The touchscreen operant platform for assessing executive function in rats and mice. Nature Protocols. 8: 1985-2005. PMID 24051960 DOI: 10.1038/nprot.2013.123  0.8
2013 Horner AE, Heath CJ, Hvoslef-Eide M, Kent BA, Kim CH, Nilsson SR, Alsiö J, Oomen CA, Holmes A, Saksida LM, Bussey TJ. The touchscreen operant platform for testing learning and memory in rats and mice. Nature Protocols. 8: 1961-84. PMID 24051959 DOI: 10.1038/nprot.2013.122  0.8
2013 Holmes A, Spanagel R, Krystal JH. Glutamatergic targets for new alcohol medications. Psychopharmacology. 229: 539-54. PMID 23995381 DOI: 10.1007/s00213-013-3226-2  0.8
2013 Griebel G, Holmes A. 50 years of hurdles and hope in anxiolytic drug discovery. Nature Reviews. Drug Discovery. 12: 667-87. PMID 23989795 DOI: 10.1038/nrd4075  0.8
2013 DePoy L, Daut R, Brigman JL, MacPherson K, Crowley N, Gunduz-Cinar O, Pickens CL, Cinar R, Saksida LM, Kunos G, Lovinger DM, Bussey TJ, Camp MC, Holmes A. Chronic alcohol produces neuroadaptations to prime dorsal striatal learning. Proceedings of the National Academy of Sciences of the United States of America. 110: 14783-8. PMID 23959891 DOI: 10.1073/pnas.1308198110  0.8
2013 Brigman JL, Daut RA, Wright T, Gunduz-Cinar O, Graybeal C, Davis MI, Jiang Z, Saksida LM, Jinde S, Pease M, Bussey TJ, Lovinger DM, Nakazawa K, Holmes A. GluN2B in corticostriatal circuits governs choice learning and choice shifting. Nature Neuroscience. 16: 1101-10. PMID 23831965 DOI: 10.1038/nn.3457  0.8
2013 Macpherson K, Whittle N, Camp M, Gunduz-Cinar O, Singewald N, Holmes A. Temporal factors in the extinction of fear in inbred mouse strains differing in extinction efficacy. Biology of Mood & Anxiety Disorders. 3: 13. PMID 23830244 DOI: 10.1186/2045-5380-3-13  0.32
2013 Maroun M, Ioannides PJ, Bergman KL, Kavushansky A, Holmes A, Wellman CL. Fear extinction deficits following acute stress associate with increased spine density and dendritic retraction in basolateral amygdala neurons. The European Journal of Neuroscience. 38: 2611-20. PMID 23714419 DOI: 10.1111/ejn.12259  0.8
2013 Kiselycznyk C, Zhang X, Huganir RL, Holmes A, Svenningsson P. Reduced phosphorylation of GluA1 subunits relates to anxiety-like behaviours in mice. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 919-24. PMID 23360771 DOI: 10.1017/S1461145712001174  0.8
2013 Holmes A, Singewald N. Individual differences in recovery from traumatic fear. Trends in Neurosciences. 36: 23-31. PMID 23260015 DOI: 10.1016/j.tins.2012.11.003  0.8
2013 Debrouse L, Hurd B, Kiselycznyk C, Plitt A, Todaro A, Mishina M, Grant SG, Camp M, Gunduz-Cinar O, Holmes A. Probing the modulation of acute ethanol intoxication by pharmacological manipulation of the NMDAR glycine co-agonist site. Alcoholism, Clinical and Experimental Research. 37: 223-33. PMID 22934986 DOI: 10.1111/j.1530-0277.2012.01922.x  0.8
2013 Whittle N, Schmuckermair C, Gunduz Cinar O, Hauschild M, Ferraguti F, Holmes A, Singewald N. Deep brain stimulation, histone deacetylase inhibitors and glutamatergic drugs rescue resistance to fear extinction in a genetic mouse model. Neuropharmacology. 64: 414-23. PMID 22722028 DOI: 10.1016/j.neuropharm.2012.06.001  0.8
2013 Gunduz-Cinar O, MacPherson KP, Cinar R, Gamble-George J, Sugden K, Williams B, Godlewski G, Ramikie TS, Gorka AX, Alapafuja SO, Nikas SP, Makriyannis A, Poulton R, Patel S, Hariri AR, ... ... Holmes A, et al. Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity. Molecular Psychiatry. 18: 813-23. PMID 22688188 DOI: 10.1038/mp.2012.72  0.8
2012 Holmes A, Fitzgerald PJ, MacPherson KP, DeBrouse L, Colacicco G, Flynn SM, Masneuf S, Pleil KE, Li C, Marcinkiewcz CA, Kash TL, Gunduz-Cinar O, Camp M. Chronic alcohol remodels prefrontal neurons and disrupts NMDAR-mediated fear extinction encoding. Nature Neuroscience. 15: 1359-61. PMID 22941108 DOI: 10.1038/nn.3204  0.8
2012 Maroun M, Kavushansky A, Holmes A, Wellman C, Motanis H. Enhanced extinction of aversive memories by high-frequency stimulation of the rat infralimbic cortex. Plos One. 7: e35853. PMID 22586453 DOI: 10.1371/journal.pone.0035853  0.8
2012 Sweetnam D, Holmes A, Tennant KA, Zamani A, Walle M, Jones P, Wong C, Brown CE. Diabetes impairs cortical plasticity and functional recovery following ischemic stroke. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 5132-43. PMID 22496559 DOI: 10.1523/JNEUROSCI.5075-11.2012  0.8
2012 Hartley CA, McKenna MC, Salman R, Holmes A, Casey BJ, Phelps EA, Glatt CE. Serotonin transporter polyadenylation polymorphism modulates the retention of fear extinction memory. Proceedings of the National Academy of Sciences of the United States of America. 109: 5493-8. PMID 22431634 DOI: 10.1073/pnas.1202044109  0.8
2012 Graybeal C, Kiselycznyk C, Holmes A. Stress-induced impairments in prefrontal-mediated behaviors and the role of the N-methyl-D-aspartate receptor. Neuroscience. 211: 28-38. PMID 22414923 DOI: 10.1016/j.neuroscience.2012.02.042  0.8
2012 Chesler EJ, Plitt A, Fisher D, Hurd B, Lederle L, Bubier JA, Kiselycznyk C, Holmes A. Quantitative trait loci for sensitivity to ethanol intoxication in a C57BL/6J×129S1/SvImJ inbred mouse cross. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 23: 305-21. PMID 22371272 DOI: 10.1007/s00335-012-9394-2  0.8
2012 Karlsson RM, Adermark L, Molander A, Perreau-Lenz S, Singley E, Solomon M, Holmes A, Tanaka K, Lovinger DM, Spanagel R, Heilig M. Reduced alcohol intake and reward associated with impaired endocannabinoid signaling in mice with a deletion of the glutamate transporter GLAST. Neuropharmacology. 63: 181-9. PMID 22342743 DOI: 10.1016/j.neuropharm.2012.01.027  0.8
2012 Camp MC, Macpherson KP, Lederle L, Graybeal C, Gaburro S, Debrouse LM, Ihne JL, Bravo JA, O'Connor RM, Ciocchi S, Wellman CL, Lüthi A, Cryan JF, Singewald N, Holmes A. Genetic strain differences in learned fear inhibition associated with variation in neuroendocrine, autonomic, and amygdala dendritic phenotypes. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 1534-47. PMID 22334122 DOI: 10.1038/npp.2011.340  0.8
2012 Graybeal C, Kiselycznyk C, Holmes A. Stress-induced deficits in cognition and emotionality: a role of glutamate. Current Topics in Behavioral Neurosciences. 12: 189-207. PMID 22261703 DOI: 10.1007/7854_2011_193  0.8
2012 Ihne JL, Fitzgerald PJ, Hefner KR, Holmes A. Pharmacological modulation of stress-induced behavioral changes in the light/dark exploration test in male C57BL/6J mice. Neuropharmacology. 62: 464-73. PMID 21906605 DOI: 10.1016/j.neuropharm.2011.08.045  0.8
2012 Barkus C, Feyder M, Graybeal C, Wright T, Wiedholz L, Izquierdo A, Kiselycznyk C, Schmitt W, Sanderson DJ, Rawlins JN, Saksida LM, Bussey TJ, Sprengel R, Bannerman D, Holmes A. Do GluA1 knockout mice exhibit behavioral abnormalities relevant to the negative or cognitive symptoms of schizophrenia and schizoaffective disorder? Neuropharmacology. 62: 1263-72. PMID 21693126 DOI: 10.1016/j.neuropharm.2011.06.005  0.8
2012 Bussey TJ, Holmes A, Lyon L, Mar AC, McAllister KA, Nithianantharajah J, Oomen CA, Saksida LM. New translational assays for preclinical modelling of cognition in schizophrenia: the touchscreen testing method for mice and rats. Neuropharmacology. 62: 1191-203. PMID 21530550 DOI: 10.1016/j.neuropharm.2011.04.011  0.8
2012 Holmes A. Genes, brain and behavior: At the Vanguard of behavioral and genomic neuroscience Genes, Brain and Behavior. 11: 1-2. DOI: 10.1111/j.1601-183X.2011.00760.x  0.8
2011 Graybeal C, Feyder M, Schulman E, Saksida LM, Bussey TJ, Brigman JL, Holmes A. Paradoxical reversal learning enhancement by stress or prefrontal cortical damage: rescue with BDNF. Nature Neuroscience. 14: 1507-9. PMID 22057192 DOI: 10.1038/nn.2954  0.8
2011 Kiselycznyk C, Svenningsson P, Delpire E, Holmes A. Genetic, pharmacological and lesion analyses reveal a selective role for corticohippocampal GLUN2B in a novel repeated swim stress paradigm. Neuroscience. 193: 259-68. PMID 21704131 DOI: 10.1016/j.neuroscience.2011.06.015  0.8
2011 Holmes A. Merger fever: Can two separate mechanisms work together to explain why we drink? Biological Psychiatry. 69: 1015-1016. PMID 21550435 DOI: 10.1016/j.biopsych.2011.04.010  0.8
2011 Camp MC, Feyder M, Ihne J, Palachick B, Hurd B, Karlsson RM, Noronha B, Chen YC, Coba MP, Grant SG, Holmes A. A novel role for PSD-95 in mediating ethanol intoxication, drinking and place preference. Addiction Biology. 16: 428-39. PMID 21309945 DOI: 10.1111/j.1369-1600.2010.00282.x  0.8
2011 Lederle L, Weber S, Wright T, Feyder M, Brigman JL, Crombag HS, Saksida LM, Bussey TJ, Holmes A. Reward-related behavioral paradigms for addiction research in the mouse: performance of common inbred strains. Plos One. 6: e15536. PMID 21249214 DOI: 10.1371/journal.pone.0015536  0.8
2011 Kiselycznyk C, Holmes A. All (C57BL/6) mice are not created equal Frontiers in Neuroscience. DOI: 10.3389/fnins.2011.00010  0.8
2010 Baganz N, Horton R, Martin K, Holmes A, Daws LC. Repeated swim impairs serotonin clearance via a corticosterone-sensitive mechanism: organic cation transporter 3, the smoking gun. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 15185-95. PMID 21068324 DOI: 10.1523/JNEUROSCI.2740-10.2010  0.8
2010 Feyder M, Karlsson RM, Mathur P, Lyman M, Bock R, Momenan R, Munasinghe J, Scattoni ML, Ihne J, Camp M, Graybeal C, Strathdee D, Begg A, Alvarez VA, Kirsch P, ... ... Holmes A, et al. Association of mouse Dlg4 (PSD-95) gene deletion and human DLG4 gene variation with phenotypes relevant to autism spectrum disorders and Williams' syndrome. The American Journal of Psychiatry. 167: 1508-17. PMID 20952458 DOI: 10.1176/appi.ajp.2010.10040484  0.8
2010 Whittle N, Hauschild M, Lubec G, Holmes A, Singewald N. Rescue of impaired fear extinction and normalization of cortico-amygdala circuit dysfunction in a genetic mouse model by dietary zinc restriction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 13586-96. PMID 20943900 DOI: 10.1523/JNEUROSCI.0849-10.2010  0.8
2010 Fitzgerald PJ, Barkus C, Feyder M, Wiedholz LM, Chen YC, Karlsson RM, Machado-Vieira R, Graybeal C, Sharp T, Zarate C, Harvey-White J, Du J, Sprengel R, Gass P, Bannerman D, ... Holmes A, et al. Does gene deletion of AMPA GluA1 phenocopy features of schizoaffective disorder? Neurobiology of Disease. 40: 608-21. PMID 20699120 DOI: 10.1016/j.nbd.2010.08.005  0.8
2010 Fraser LM, Brown RE, Hussin A, Fontana M, Whittaker A, O'Leary TP, Lederle L, Holmes A, Ramos A. Measuring anxiety- and locomotion-related behaviours in mice: a new way of using old tests. Psychopharmacology. 211: 99-112. PMID 20454890 DOI: 10.1007/s00213-010-1873-0  0.8
2010 Mozhui K, Karlsson RM, Kash TL, Ihne J, Norcross M, Patel S, Farrell MR, Hill EE, Graybeal C, Martin KP, Camp M, Fitzgerald PJ, Ciobanu DC, Sprengel R, Mishina M, ... ... Holmes A, et al. Strain differences in stress responsivity are associated with divergent amygdala gene expression and glutamate-mediated neuronal excitability. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 5357-67. PMID 20392957 DOI: 10.1523/JNEUROSCI.5017-09.2010  0.8
2010 Brigman JL, Wright T, Talani G, Prasad-Mulcare S, Jinde S, Seabold GK, Mathur P, Davis MI, Bock R, Gustin RM, Colbran RJ, Alvarez VA, Nakazawa K, Delpire E, Lovinger DM, ... Holmes A, et al. Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learning. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 4590-600. PMID 20357110 DOI: 10.1523/JNEUROSCI.0640-10.2010  0.8
2010 Holmes A, Quirk GJ. Pharmacological facilitation of fear extinction and the search for adjunct treatments for anxiety disorders--the case of yohimbine. Trends in Pharmacological Sciences. 31: 2-7. PMID 20036429 DOI: 10.1016/  0.8
2010 Brigman JL, Mathur P, Harvey-White J, Izquierdo A, Saksida LM, Bussey TJ, Fox S, Deneris E, Murphy DL, Holmes A. Pharmacological or genetic inactivation of the serotonin transporter improves reversal learning in mice. Cerebral Cortex (New York, N.Y. : 1991). 20: 1955-63. PMID 20032063 DOI: 10.1093/cercor/bhp266  0.8
2010 Brigman JL, Graybeal C, Holmes A. Predictably irrational: Assaying cognitive inflexibility in mouse models of schizophrenia Frontiers in Neuroscience. 4: 19-28. DOI: 10.3389/neuro.01.013.2010  0.8
2010 Feyder M, Camp MC, Holmes A, Chen YC. Ethanol and NMDA receptor interactions: Implications for pharmacotherapeutic treatments Journal of Medical Sciences. 30: 003-010.  0.8
2009 Zhou R, Holmes A, Du J, Malkesman O, Yuan P, Wang Y, Damschroder-Williams P, Chen G, Guitart X, Manji HK. Genome-wide gene expression profiling in GluR1 knockout mice: Key role of the calcium signaling pathway in glutamatergically mediated hippocampal transmission European Journal of Neuroscience. 30: 2318-2326. PMID 20092574 DOI: 10.1111/j.1460-9568.2009.07022.x  0.8
2009 Witkiewitz K, Holmes A, Ray LA, Murphy JG, Richardson HN, Chen YC, McDevitt-Murphy ME, Cruz MT, Roberto M. Young Investigator Award symposium. Alcohol (Fayetteville, N.Y.). 43: 499-508. PMID 19913193 DOI: 10.1016/j.alcohol.2009.06.004  0.8
2009 Metcalfe S, Woodward A, Macmillan A, Baker M, Howden-Chapman P, Lindsay G, Hales S, Sinclair D, Jaine R, Springford L, Holmes A, Laking G, Jones R, Carr H, Edwards R, et al. Why New Zealand must rapidly halve its greenhouse gas emissions. The New Zealand Medical Journal. 122: 72-95. PMID 19859094  0.8
2009 Camp M, Norcross M, Whittle N, Feyder M, D'Hanis W, Yilmazer-Hanke D, Singewald N, Holmes A. Impaired Pavlovian fear extinction is a common phenotype across genetic lineages of the 129 inbred mouse strain. Genes, Brain, and Behavior. 8: 744-52. PMID 19674120 DOI: 10.1111/j.1601-183X.2009.00519.x  0.8
2009 Brigman JL, Ihne J, Saksida LM, Bussey TJ, Holmes A. Effects of Subchronic Phencyclidine (PCP) Treatment on Social Behaviors, and Operant Discrimination and Reversal Learning in C57BL/6J Mice. Frontiers in Behavioral Neuroscience. 3: 2. PMID 19255630 DOI: 10.3389/neuro.08.002.2009  0.8
2009 Holmes A, Wellman CL. Stress-induced prefrontal reorganization and executive dysfunction in rodents. Neuroscience and Biobehavioral Reviews. 33: 773-83. PMID 19111570 DOI: 10.1016/j.neubiorev.2008.11.005  0.8
2009 Karlsson RM, Tanaka K, Saksida LM, Bussey TJ, Heilig M, Holmes A. Assessment of glutamate transporter GLAST (EAAT1)-deficient mice for phenotypes relevant to the negative and executive/cognitive symptoms of schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 1578-89. PMID 19078949 DOI: 10.1038/npp.2008.215  0.8
2009 Chen YC, Holmes A. Effects of topiramate and other anti-glutamatergic drugs on the acute intoxicating actions of ethanol in mice: Modulation by genetic strain and stress Neuropsychopharmacology. 34: 1454-1466. PMID 18843265 DOI: 10.1038/npp.2008.182  0.8
2009 Brigman JL, Mathur P, Lu L, Williams RW, Holmes A. Genetic relationship between anxiety-related and fear-related behaviors in BXD recombinant inbred mice. Behavioural Pharmacology. 20: 204-9. PMID 18830130 DOI: 10.1097/FBP.0b013e32830c368c  0.8
2009 Mathur P, Graybeal C, Feyder M, Davis MI, Holmes A. Fear memory impairing effects of systemic treatment with the NMDA NR2B subunit antagonist, Ro 25-6981, in mice: attenuation with ageing. Pharmacology, Biochemistry, and Behavior. 91: 453-60. PMID 18809426 DOI: 10.1016/j.pbb.2008.08.028  0.8
2009 Crusio WE, Goldowitz D, Holmes A, Wolfer D. Standards for the publication of mouse mutant studies. Genes, Brain, and Behavior. 8: 1-4. PMID 18778401 DOI: 10.1111/j.1601-183X.2008.00438.x  0.8
2008 Murphy DL, Fox MA, Timpano KR, Moya PR, Ren-Patterson R, Andrews AM, Holmes A, Lesch KP, Wendland JR. How the serotonin story is being rewritten by new gene-based discoveries principally related to SLC6A4, the serotonin transporter gene, which functions to influence all cellular serotonin systems. Neuropharmacology. 55: 932-60. PMID 18824000 DOI: 10.1016/j.neuropharm.2008.08.034  0.8
2008 Davis AR, Shields AD, Brigman JL, Norcross M, McElligott ZA, Holmes A, Winder DG. Yohimbine impairs extinction of cocaine-conditioned place preference in an alpha2-adrenergic receptor independent process. Learning & Memory (Cold Spring Harbor, N.Y.). 15: 667-76. PMID 18772254 DOI: 10.1101/lm.1079308  0.8
2008 Parker CC, Ponicsan H, Spencer RL, Holmes A, Johnson TE. Restraint stress and exogenous corticosterone differentially alter sensitivity to the sedative-hypnotic effects of ethanol in inbred long-sleep and inbred short-sleep mice. Alcohol (Fayetteville, N.Y.). 42: 477-85. PMID 18760716 DOI: 10.1016/j.alcohol.2008.05.004  0.8
2008 Fegley DB, Holmes A, Riordan T, Faber CA, Weiss JR, Ma S, Batkai S, Pacher P, Dobolyi A, Murphy A, Sleeman MW, Usdin TB. Increased fear- and stress-related anxiety-like behavior in mice lacking tuberoinfundibular peptide of 39 residues. Genes, Brain, and Behavior. 7: 933-42. PMID 18700839 DOI: 10.1111/j.1601-183X.2008.00432.x  0.8
2008 Hefner K, Whittle N, Juhasz J, Norcross M, Karlsson RM, Saksida LM, Bussey TJ, Singewald N, Holmes A. Impaired fear extinction learning and cortico-amygdala circuit abnormalities in a common genetic mouse strain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 8074-85. PMID 18685032 DOI: 10.1523/JNEUROSCI.4904-07.2008  0.8
2008 Boyce-Rustay JM, Palachick B, Hefner K, Chen YC, Karlsson RM, Millstein RA, Harvey-White J, Holmes A. Desipramine potentiation of the acute depressant effects of ethanol: modulation by alpha2-adrenoreceptors and stress. Neuropharmacology. 55: 803-11. PMID 18625256 DOI: 10.1016/j.neuropharm.2008.06.032  0.8
2008 Karlsson RM, Hefner KR, Sibley DR, Holmes A. Comparison of dopamine D1 and D5 receptor knockout mice for cocaine locomotor sensitization. Psychopharmacology. 200: 117-27. PMID 18600316 DOI: 10.1007/s00213-008-1165-0  0.8
2008 Norcross M, Mathur P, Poonam M, Enoch AJ, Karlsson RM, Brigman JL, Cameron HA, Harvey-White J, Holmes A. Effects of adolescent fluoxetine treatment on fear-, anxiety- or stress-related behaviors in C57BL/6J or BALB/cJ mice. Psychopharmacology. 200: 413-24. PMID 18594797 DOI: 10.1007/s00213-008-1215-7  0.8
2008 Palachick B, Chen YC, Enoch AJ, Karlsson RM, Mishina M, Holmes A. Role of major NMDA or AMPA receptor subunits in MK-801 potentiation of ethanol intoxication. Alcoholism, Clinical and Experimental Research. 32: 1479-92. PMID 18565157 DOI: 10.1111/j.1530-0277.2008.00715.x  0.8
2008 Adamec R, Holmes A, Blundell J. Vulnerability to lasting anxiogenic effects of brief exposure to predator stimuli: sex, serotonin and other factors-relevance to PTSD. Neuroscience and Biobehavioral Reviews. 32: 1287-92. PMID 18550167 DOI: 10.1016/j.neubiorev.2008.05.005  0.8
2008 Karlsson RM, Tanaka K, Heilig M, Holmes A. Loss of glial glutamate and aspartate transporter (excitatory amino acid transporter 1) causes locomotor hyperactivity and exaggerated responses to psychotomimetics: rescue by haloperidol and metabotropic glutamate 2/3 agonist. Biological Psychiatry. 64: 810-4. PMID 18550032 DOI: 10.1016/j.biopsych.2008.05.001  0.8
2008 Holmes A. Genetic variation in cortico-amygdala serotonin function and risk for stress-related disease Neuroscience and Biobehavioral Reviews. 32: 1293-1314. PMID 18439676 DOI: 10.1016/j.neubiorev.2008.03.006  0.8
2008 Brigman JL, Feyder M, Saksida LM, Bussey TJ, Mishina M, Holmes A. Impaired discrimination learning in mice lacking the NMDA receptor NR2A subunit. Learning & Memory (Cold Spring Harbor, N.Y.). 15: 50-4. PMID 18230672 DOI: 10.1101/lm.777308  0.8
2008 Yang RJ, Mozhui K, Karlsson RM, Cameron HA, Williams RW, Holmes A. Variation in mouse basolateral amygdala volume is associated with differences in stress reactivity and fear learning. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 2595-604. PMID 18185497 DOI: 10.1038/sj.npp.1301665  0.8
2008 Krystal JH, Gueorguieva R, Cramer J, Collins J, Rosenheck R. Naltrexone is associated with reduced drinking by alcohol dependent patients receiving antidepressants for mood and anxiety symptoms: results from VA Cooperative Study No. 425, "Naltrexone in the treatment of alcoholism". Alcoholism, Clinical and Experimental Research. 32: 85-91. PMID 18070245 DOI: 10.1111/j.1530-0277.2007.00555.x  0.8
2008 Karlsson RM, Choe JS, Cameron HA, Thorsell A, Crawley JN, Holmes A, Heilig M. The neuropeptide Y Y1 receptor subtype is necessary for the anxiolytic-like effects of neuropeptide Y, but not the antidepressant-like effects of fluoxetine, in mice. Psychopharmacology. 195: 547-57. PMID 17891380 DOI: 10.1007/s00213-007-0945-2  0.8
2008 Boyce-Rustay JM, Janos AL, Holmes A. Effects of chronic swim stress on EtOH-related behaviors in C57BL/6J, DBA/2J and BALB/cByJ mice. Behavioural Brain Research. 186: 133-7. PMID 17822784 DOI: 10.1016/j.bbr.2007.07.031  0.8
2008 Wiedholz LM, Owens WA, Horton RE, Feyder M, Karlsson RM, Hefner K, Sprengel R, Celikel T, Daws LC, Holmes A. Mice lacking the AMPA GluR1 receptor exhibit striatal hyperdopaminergia and 'schizophrenia-related' behaviors. Molecular Psychiatry. 13: 631-40. PMID 17684498 DOI: 10.1038/  0.8
2008 Tonelli LH, Holmes A, Postolache TT. Intranasal immune challenge induces sex-dependent depressive-like behavior and cytokine expression in the brain Neuropsychopharmacology. 33: 1038-1048. PMID 17593929 DOI: 10.1038/sj.npp.1301488  0.8
2008 Holmes A. Chapter 4.7 The pharmacology of anxiolysis Handbook of Behavioral Neuroscience. 17: 355-361. DOI: 10.1016/S1569-7339(07)00016-1  0.8
2008 Steckler T, Stein MB, Holmes A. Developing novel anxiolytics: Improving preclinical detection and clinical assessment Animal and Translational Models For Cns Drug Discovery. 1: 117-132. DOI: 10.1016/B978-0-12-373861-5.00005-9  0.8
2008 Norcross M, Mathur P, Enoch AJ, Karlsson RM, Brigman JL, Cameron HA, Harvey-White J, Holmes A. Effects of adolescent fluoxetine treatment on fear-, anxiety-or stress-related behaviors in C57BL/6J or BALB/cJ mice Psychopharmacology. 200: 453. DOI: 10.1007/s00213-008-1297-2  0.8
2007 Wellman CL, Izquierdo A, Garrett JE, Martin KP, Carroll J, Millstein R, Lesch KP, Murphy DL, Holmes A. Impaired stress-coping and fear extinction and abnormal corticolimbic morphology in serotonin transporter knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 684-91. PMID 17234600 DOI: 10.1523/JNEUROSCI.4595-06.2007  0.8
2007 Feyder M, Wiedholz L, Sprengel R, Holmes A. Impaired associative fear learning in mice with complete loss or haploinsufficiency of AMPA GluR1 receptors Frontiers in Behavioral Neuroscience. 1. DOI: 10.3389/neuro.08.004.2007 10.3389/neuro.08.004.2007  0.8
2007 Nichols T, Holmes A. Non-parametric procedures Statistical Parametric Mapping: the Analysis of Functional Brain Images. 253-272. DOI: 10.1016/B978-012372560-8/50021-8  0.8
2006 Izquierdo A, Wellman CL, Holmes A. Brief uncontrollable stress causes dendritic retraction in infralimbic cortex and resistance to fear extinction in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5733-8. PMID 16723530 DOI: 10.1523/JNEUROSCI.0474-06.2006  0.8
2006 Izquierdo A, Wiedholz LM, Millstein RA, Yang RJ, Bussey TJ, Saksida LM, Holmes A. Genetic and dopaminergic modulation of reversal learning in a touchscreen-based operant procedure for mice. Behavioural Brain Research. 171: 181-8. PMID 16713639 DOI: 10.1016/j.bbr.2006.03.029  0.8
2005 Rustay NR, Wrenn CC, Kinney JW, Holmes A, Bailey KR, Sullivan TL, Harris AP, Long KC, Saavedra MC, Starosta G, Innerfield CE, Yang RJ, Dreiling JL, Crawley JN. Galanin impairs performance on learning and memory tasks: findings from galanin transgenic and GAL-R1 knockout mice. Neuropeptides. 39: 239-43. PMID 15944016 DOI: 10.1016/j.npep.2004.12.026  0.8
2005 Karlsson RM, Holmes A, Heilig M, Crawley JN. Anxiolytic-like actions of centrally-administered neuropeptide Y, but not galanin, in C57BL/6J mice. Pharmacology, Biochemistry, and Behavior. 80: 427-36. PMID 15740785 DOI: 10.1016/j.pbb.2004.12.009  0.8
2005 Holmes A, Li Q, Koenig EA, Gold E, Stephenson D, Yang RJ, Dreiling J, Sullivan T, Crawley JN. Phenotypic assessment of galanin overexpressing and galanin receptor R1 knockout mice in the tail suspension test for depression-related behavior. Psychopharmacology. 178: 276-85. PMID 15365683 DOI: 10.1007/s00213-004-1997-1  0.8
2004 Wrenn CC, Kinney JW, Marriott LK, Holmes A, Harris AP, Saavedra MC, Starosta G, Innerfield CE, Jacoby AS, Shine J, Iismaa TP, Wenk GL, Crawley JN. Learning and memory performance in mice lacking the GAL-R1 subtype of galanin receptor. The European Journal of Neuroscience. 19: 1384-96. PMID 15016096 DOI: 10.1111/j.1460-9568.2004.03214.x  0.8
2003 Holmes A, Lit Q, Murphy DL, Gold E, Crawley JN. Abnormal anxiety-related behavior in serotonin transporter null mutant mice: the influence of genetic background. Genes, Brain, and Behavior. 2: 365-80. PMID 14653308  0.44
2003 Holmes A, Murphy DL, Crawley JN. Abnormal behavioral phenotypes of serotonin transporter knockout mice: parallels with human anxiety and depression. Biological Psychiatry. 54: 953-9. PMID 14625137  0.44
2003 Holmes A, Yang RJ, Lesch KP, Crawley JN, Murphy DL. Mice lacking the serotonin transporter exhibit 5-HT(1A) receptor-mediated abnormalities in tests for anxiety-like behavior. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 2077-88. PMID 12968128 DOI: 10.1038/sj.npp.1300266  0.44
2003 Holmes A, Kinney JW, Wrenn CC, Li Q, Yang RJ, Ma L, Vishwanath J, Saavedra MC, Innerfield CE, Jacoby AS, Shine J, Iismaa TP, Crawley JN. Galanin GAL-R1 receptor null mutant mice display increased anxiety-like behavior specific to the elevated plus-maze. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1031-44. PMID 12700679 DOI: 10.1038/sj.npp.1300164  0.44
2002 Holmes A, Wrenn CC, Harris AP, Thayer KE, Crawley JN. Behavioral profiles of inbred strains on novel olfactory, spatial and emotional tests for reference memory in mice. Genes, Brain, and Behavior. 1: 55-69. PMID 12886950  0.44
2002 Wrenn CC, Marriott LK, Kinney JW, Holmes A, Wenk GL, Crawley JN. Galanin peptide levels in hippocampus and cortex of galanin-overexpressing transgenic mice evaluated for cognitive performance. Neuropeptides. 36: 413-26. PMID 12507436 DOI: 10.1016/S0143-4179(02)00111-7  0.8
2002 Holmes A, Yang RJ, Murphy DL, Crawley JN. Evaluation of antidepressant-related behavioral responses in mice lacking the serotonin transporter. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 27: 914-23. PMID 12464448 DOI: 10.1016/S0893-133X(02)00374-3  0.44
2002 Kinney JW, Starosta G, Holmes A, Wrenn CC, Yang RJ, Harris AP, Long KC, Crawley JN. Deficits in trace cued fear conditioning in galanin-treated rats and galanin-overexpressing transgenic mice. Learning & Memory (Cold Spring Harbor, N.Y.). 9: 178-90. PMID 12177231 DOI: 10.1101/m.49502  0.44
2002 Holmes A, Murphy DL, Crawley JN. Reduced aggression in mice lacking the serotonin transporter. Psychopharmacology. 161: 160-7. PMID 11981596 DOI: 10.1007/s00213-002-1024-3  0.44
2002 Holmes A, Yang RJ, Crawley JN. Evaluation of an anxiety-related phenotype in galanin overexpressing transgenic mice. Journal of Molecular Neuroscience : Mn. 18: 151-65. PMID 11931346 DOI: 10.1385/JMN:18:1-2:151  0.44
2001 Holmes A, Hollon TR, Gleason TC, Liu Z, Dreiling J, Sibley DR, Crawley JN. Behavioral characterization of dopamine D5 receptor null mutant mice. Behavioral Neuroscience. 115: 1129-44. PMID 11584926 DOI: 10.1037/0735-7044.115.5.1129  0.8
2001 Steiner RA, Hohmann JG, Holmes A, Wrenn CC, Cadd G, Juréus A, Clifton DK, Luo M, Gutshall M, Ma SY, Mufson EJ, Crawley JN. Galanin transgenic mice display cognitive and neurochemical deficits characteristic of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 98: 4184-9. PMID 11259657 DOI: 10.1073/pnas.061445598  0.8
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