| Year |
Citation |
Score |
| 2021 |
Langer K, Müller-Längle A, Wempe J, Laube B. Analysis of M4 Transmembrane Segments in NMDA Receptor Function: A Negative Allosteric Modulatory Site at the GluN1 M4 is Determining the Efficiency of Neurosteroid Modulation. Frontiers in Pharmacology. 12: 769046. PMID 34658899 DOI: 10.3389/fphar.2021.769046 |
0.42 |
|
| 2020 |
Bernhard M, Laube B. Thermophoretic analysis of ligand-specific conformational states of the inhibitory glycine receptor embedded in copolymer nanodiscs. Scientific Reports. 10: 16569. PMID 33024136 DOI: 10.1038/s41598-020-73157-2 |
0.389 |
|
| 2019 |
Bernhard M, Diefenbach M, Biesalski M, Laube B. Electrical sensing of phosphonates by functional coupling of phosphonate binding protein PhnD to solid-state nanopores. Acs Sensors. PMID 31829017 DOI: 10.1021/acssensors.9b02097 |
0.322 |
|
| 2019 |
Müller-Längle A, Lutz H, Hehlgans S, Rödel F, Rau K, Laube B. NMDA Receptor-Mediated Signaling Pathways Enhance Radiation Resistance, Survival and Migration in Glioblastoma Cells-A Potential Target for Adjuvant Radiotherapy. Cancers. 11. PMID 30970642 DOI: 10.3390/cancers11040503 |
0.44 |
|
| 2019 |
Lutz H, Nguyen TA, Joswig J, Rau K, Laube B. NMDA Receptor Signaling Mediates cFos Expression via Top2β-Induced DSBs in Glioblastoma Cells. Cancers. 11. PMID 30841565 DOI: 10.3390/cancers11030306 |
0.417 |
|
| 2019 |
Schönrock M, Thiel G, Laube B. Coupling of a viral K-channel with a glutamate-binding-domain highlights the modular design of ionotropic glutamate-receptors. Communications Biology. 2: 75. PMID 30820470 DOI: 10.1038/s42003-019-0320-y |
0.399 |
|
| 2019 |
Bledsoe D, Vacca B, Laube B, Klein BG, Costa B. Ligand binding domain interface: A tipping point for pharmacological agents binding with GluN1/2A subunit containing NMDA receptors. European Journal of Pharmacology. 844: 216-224. PMID 30553788 DOI: 10.1016/j.ejphar.2018.12.023 |
0.645 |
|
| 2018 |
Richter MC, Ludewig S, Winschel A, Abel T, Bold C, Salzburger LR, Klein S, Han K, Weyer SW, Fritz AK, Laube B, Wolfer DP, Buchholz CJ, Korte M, Müller UC. Distinct roles of secreted APP ectodomain variants APPsα and APPsβ in regulation of spine density, synaptic plasticity, and cognition. The Embo Journal. PMID 29661886 DOI: 10.15252/embj.201798335 |
0.356 |
|
| 2017 |
Bledsoe D, Tamer C, Mesic I, Madry C, Klein BG, Laube B, Costa BM. Positive Modulatory Interactions of NMDA Receptor GluN1/2B Ligand Binding Domains Attenuate Antagonists Activity. Frontiers in Pharmacology. 8: 229. PMID 28536523 DOI: 10.3389/fphar.2017.00229 |
0.854 |
|
| 2017 |
Bernhard M, Laube B. Functional Coupling of Bacterial Binding Protein with the Channel Pore of an Ionotropic Glutamate Receptor Biophysical Journal. 112: 419a. DOI: 10.1016/J.BPJ.2016.11.2243 |
0.523 |
|
| 2017 |
Schoenrock M, Poci A, Thiel G, Laube B. Design of a Glutamate-Activated Potassium Channel upon Fusion of the Ligand-Binding Domain of the Mammalian AMPA Receptor Glua1 to the Channel Pore of the Viral ATCV-1 KCV K + Channel Biophysical Journal. 112: 418a-419a. DOI: 10.1016/J.Bpj.2016.11.2240 |
0.435 |
|
| 2016 |
Lemke JR, Geider K, Helbig KL, Heyne HO, Schütz H, Hentschel J, Courage C, Depienne C, Nava C, Heron D, Møller RS, Hjalgrim H, Lal D, Neubauer BA, Nürnberg P, ... ... Laube B, et al. Delineating the GRIN1 phenotypic spectrum: A distinct genetic NMDA receptor encephalopathy. Neurology. PMID 27164704 DOI: 10.1212/Wnl.0000000000002740 |
0.567 |
|
| 2016 |
Mesic I, Madry C, Geider K, Bernhard M, Betz H, Laube B. The N-terminal Domain of the GluN3A Subunit determines the Efficacy of Glycine-activated NMDA Receptors. Neuropharmacology. PMID 26777280 DOI: 10.1016/j.neuropharm.2016.01.014 |
0.859 |
|
| 2015 |
Lynagh T, Beech RN, Lalande MJ, Keller K, Cromer BA, Wolstenholme AJ, Laube B. Molecular basis for convergent evolution of glutamate recognition by pentameric ligand-gated ion channels. Scientific Reports. 5: 8558. PMID 25708000 DOI: 10.1038/srep08558 |
0.479 |
|
| 2014 |
Lynagh T, Cromer BA, Dufour V, Laube B. Comparative pharmacology of flatworm and roundworm glutamate-gated chloride channels: Implications for potential anthelmintics. International Journal For Parasitology. Drugs and Drug Resistance. 4: 244-55. PMID 25516835 DOI: 10.1016/j.ijpddr.2014.07.004 |
0.434 |
|
| 2014 |
Lynagh T, Laube B. Opposing effects of the anesthetic propofol at pentameric ligand-gated ion channels mediated by a common site. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 2155-9. PMID 24501356 DOI: 10.1523/JNEUROSCI.4307-13.2014 |
0.442 |
|
| 2014 |
Lemke JR, Hendrickx R, Geider K, Laube B, Schwake M, Harvey RJ, James VM, Pepler A, Steiner I, Hörtnagel K, Neidhardt J, Ruf S, Wolff M, Bartholdi D, Caraballo R, et al. GRIN2B mutations in West syndrome and intellectual disability with focal epilepsy. Annals of Neurology. 75: 147-54. PMID 24272827 DOI: 10.1002/ana.24073 |
0.381 |
|
| 2013 |
Lynagh T, Kunz A, Laube B. Propofol modulation of α1 glycine receptors does not require a structural transition at adjacent subunits that is crucial to agonist-induced activation. Acs Chemical Neuroscience. 4: 1469-78. PMID 23992940 DOI: 10.1021/cn400134p |
0.531 |
|
| 2012 |
Dutertre S, Drwal M, Laube B, Betz H. Probing the pharmacological properties of distinct subunit interfaces within heteromeric glycine receptors reveals a functional ββ agonist-binding site. Journal of Neurochemistry. 122: 38-47. PMID 22486198 DOI: 10.1111/j.1471-4159.2012.07755.x |
0.774 |
|
| 2012 |
Costa BM, Irvine MW, Fang G, Eaves RJ, Mayo-Martin MB, Laube B, Jane DE, Monaghan DT. Structure-activity relationships for allosteric NMDA receptor inhibitors based on 2-naphthoic acid. Neuropharmacology. 62: 1730-6. PMID 22155206 DOI: 10.1016/J.Neuropharm.2011.11.019 |
0.587 |
|
| 2012 |
Kallenborn-Gerhardt W, Lu R, Lorenz J, Gao W, Weiland J, Del Turco D, Deller T, Laube B, Betz H, Geisslinger G, Schmidtko A. Prolonged zymosan-induced inflammatory pain hypersensitivity in mice lacking glycine receptor alpha2. Behavioural Brain Research. 226: 106-11. PMID 21924294 DOI: 10.1016/j.bbr.2011.09.002 |
0.645 |
|
| 2010 |
Endele S, Rosenberger G, Geider K, Popp B, Tamer C, Stefanova I, Milh M, Kortüm F, Fritsch A, Pientka FK, Hellenbroich Y, Kalscheuer VM, Kohlhase J, Moog U, Rappold G, ... ... Laube B, et al. Mutations in GRIN2A and GRIN2B encoding regulatory subunits of NMDA receptors cause variable neurodevelopmental phenotypes. Nature Genetics. 42: 1021-6. PMID 20890276 DOI: 10.1038/Ng.677 |
0.591 |
|
| 2010 |
Madry C, Betz H, Geiger JR, Laube B. Potentiation of Glycine-Gated NR1/NR3A NMDA Receptors Relieves Ca-Dependent Outward Rectification. Frontiers in Molecular Neuroscience. 3: 6. PMID 20407581 DOI: 10.3389/fnmol.2010.00006 |
0.848 |
|
| 2010 |
Haeger S, Kuzmin D, Detro-Dassen S, Lang N, Kilb M, Tsetlin V, Betz H, Laube B, Schmalzing G. An intramembrane aromatic network determines pentameric assembly of Cys-loop receptors. Nature Structural & Molecular Biology. 17: 90-8. PMID 20023641 DOI: 10.1038/Nsmb.1721 |
0.776 |
|
| 2010 |
Haeger S, Kuzmin D, Detro-Dassen S, Lang N, Kilb M, Tsetlin V, Betz H, Laube B, Schmalzing G. Aromatic Interfaces between Transmembrane Helices M1/M4 and M3/M4 Play a Key Role in Cys-loop Receptor Assembly Biophysical Journal. 98: 417a-418a. DOI: 10.1016/J.Bpj.2009.12.2256 |
0.768 |
|
| 2009 |
Maksay G, Laube B, Schemm R, Grudzinska J, Drwal M, Betz H. Different binding modes of tropeines mediating inhibition and potentiation of alpha1 glycine receptors. Journal of Neurochemistry. 109: 1725-32. PMID 19383091 DOI: 10.1111/j.1471-4159.2009.06083.x |
0.723 |
|
| 2009 |
Schumann T, Grudzinska J, Kuzmin D, Betz H, Laube B. Binding-site mutations in the alpha1 subunit of the inhibitory glycine receptor convert the inhibitory metal ion Cu2+ into a positive modulator. Neuropharmacology. 56: 310-7. PMID 18793654 DOI: 10.1016/J.Neuropharm.2008.08.024 |
0.759 |
|
| 2008 |
Madry C, Betz H, Geiger JR, Laube B. Supralinear potentiation of NR1/NR3A excitatory glycine receptors by Zn2+ and NR1 antagonist. Proceedings of the National Academy of Sciences of the United States of America. 105: 12563-8. PMID 18711142 DOI: 10.1073/pnas.0805624105 |
0.856 |
|
| 2008 |
Grudzinska J, Schumann T, Schemm R, Betz H, Laube B. Mutations within the agonist-binding site convert the homomeric alpha1 glycine receptor into a Zn2+-activated chloride channel. Channels (Austin, Tex.). 2: 13-8. PMID 18690053 DOI: 10.4161/chan.2.1.5931 |
0.731 |
|
| 2008 |
Schüler T, Mesic I, Madry C, Bartholomäus I, Laube B. Formation of NR1/NR2 and NR1/NR3 heterodimers constitutes the initial step in N-methyl-D-aspartate receptor assembly. The Journal of Biological Chemistry. 283: 37-46. PMID 17959602 DOI: 10.1074/jbc.M703539200 |
0.853 |
|
| 2008 |
Maksay G, Bíró T, Laube B, Nemes P. Hyperekplexia mutation R271L of alpha1 glycine receptors potentiates allosteric interactions of nortropeines, propofol and glycine with [3H]strychnine binding. Neurochemistry International. 52: 235-40. PMID 17655979 DOI: 10.1016/j.neuint.2007.06.009 |
0.468 |
|
| 2007 |
Madry C, Mesic I, Betz H, Laube B. The N-terminal domains of both NR1 and NR2 subunits determine allosteric Zn2+ inhibition and glycine affinity of N-methyl-D-aspartate receptors. Molecular Pharmacology. 72: 1535-44. PMID 17878266 DOI: 10.1124/mol.107.040071 |
0.855 |
|
| 2007 |
Papadopoulos T, Korte M, Eulenburg V, Kubota H, Retiounskaia M, Harvey RJ, Harvey K, O'Sullivan GA, Laube B, Hülsmann S, Geiger JR, Betz H. Impaired GABAergic transmission and altered hippocampal synaptic plasticity in collybistin-deficient mice. The Embo Journal. 26: 3888-99. PMID 17690689 DOI: 10.1038/sj.emboj.7601819 |
0.78 |
|
| 2007 |
Madry C, Mesic I, Bartholomäus I, Nicke A, Betz H, Laube B. Principal role of NR3 subunits in NR1/NR3 excitatory glycine receptor function. Biochemical and Biophysical Research Communications. 354: 102-8. PMID 17214961 DOI: 10.1016/J.Bbrc.2006.12.153 |
0.857 |
|
| 2007 |
Maier W, Schemm R, Grewer C, Laube B. Disruption of interdomain interactions in the glutamate binding pocket affects differentially agonist affinity and efficacy of N-methyl-D-aspartate receptor activation. The Journal of Biological Chemistry. 282: 1863-72. PMID 17105731 DOI: 10.1074/jbc.M608156200 |
0.6 |
|
| 2006 |
Hirzel K, Müller U, Latal AT, Hülsmann S, Grudzinska J, Seeliger MW, Betz H, Laube B. Hyperekplexia phenotype of glycine receptor alpha1 subunit mutant mice identifies Zn(2+) as an essential endogenous modulator of glycinergic neurotransmission. Neuron. 52: 679-90. PMID 17114051 DOI: 10.1016/j.neuron.2006.09.035 |
0.705 |
|
| 2006 |
Betz H, Laube B. Glycine receptors: recent insights into their structural organization and functional diversity. Journal of Neurochemistry. 97: 1600-10. PMID 16805771 DOI: 10.1111/j.1471-4159.2006.03908.x |
0.69 |
|
| 2005 |
Kondratskaya EL, Betz H, Krishtal OA, Laube B. The beta subunit increases the ginkgolide B sensitivity of inhibitory glycine receptors. Neuropharmacology. 49: 945-51. PMID 16125206 DOI: 10.1016/J.Neuropharm.2005.07.001 |
0.715 |
|
| 2005 |
Chandra T, Maier W, König HG, Hirzel K, Kögel D, Schüler T, Chandra A, Demirhan I, Laube B. Molecular interactions of the type 1 human immunodeficiency virus transregulatory protein Tat with N-methyl-d-aspartate receptor subunits. Neuroscience. 134: 145-53. PMID 15964699 DOI: 10.1016/j.neuroscience.2005.02.049 |
0.578 |
|
| 2005 |
Grudzinska J, Schemm R, Haeger S, Nicke A, Schmalzing G, Betz H, Laube B. The beta subunit determines the ligand binding properties of synaptic glycine receptors. Neuron. 45: 727-39. PMID 15748848 DOI: 10.1016/J.Neuron.2005.01.028 |
0.733 |
|
| 2005 |
Maier W, Corrie JE, Papageorgiou G, Laube B, Grewer C. Comparative analysis of inhibitory effects of caged ligands for the NMDA receptor. Journal of Neuroscience Methods. 142: 1-9. PMID 15652611 DOI: 10.1016/j.jneumeth.2004.07.006 |
0.584 |
|
| 2004 |
Laube B, Schemm R, Betz H. Molecular determinants of ligand discrimination in the glutamate-binding pocket of the NMDA receptor. Neuropharmacology. 47: 994-1007. PMID 15555634 DOI: 10.1016/j.neuropharm.2004.07.041 |
0.777 |
|
| 2004 |
O'Shea SM, Becker L, Weiher H, Betz H, Laube B. Propofol restores the function of "hyperekplexic" mutant glycine receptors in Xenopus oocytes and mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 2322-7. PMID 14999083 DOI: 10.1523/Jneurosci.4675-03.2004 |
0.701 |
|
| 2003 |
Gomeza J, Ohno K, Hülsmann S, Armsen W, Eulenburg V, Richter DW, Laube B, Betz H. Deletion of the mouse glycine transporter 2 results in a hyperekplexia phenotype and postnatal lethality. Neuron. 40: 797-806. PMID 14622583 DOI: 10.1016/S0896-6273(03)00673-1 |
0.745 |
|
| 2003 |
Ortinau S, Laube B, Zimmermann H. ATP inhibits NMDA receptors after heterologous expression and in cultured hippocampal neurons and attenuates NMDA-mediated neurotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 4996-5003. PMID 12832522 DOI: 10.1523/Jneurosci.23-12-04996.2003 |
0.571 |
|
| 2003 |
Foucaud B, Laube B, Schemm R, Kreimeyer A, Goeldner M, Betz H. Structural model of the N-methyl-D-aspartate receptor glycine site probed by site-directed chemical coupling. The Journal of Biological Chemistry. 278: 24011-7. PMID 12697759 DOI: 10.1074/Jbc.M300219200 |
0.798 |
|
| 2003 |
Sadtler S, Laube B, Lashub A, Nicke A, Betz H, Schmalzing G. A basic cluster determines topology of the cytoplasmic M3-M4 loop of the glycine receptor alpha1 subunit. The Journal of Biological Chemistry. 278: 16782-90. PMID 12611885 DOI: 10.1074/Jbc.M213077200 |
0.641 |
|
| 2002 |
Perret P, Laube B, Schemm R, Betz H, Goeldner M, Foucaud B. Affinity labeling of cysteine-mutants evidences contact residues in modeled receptor binding sites. Journal of Receptor and Signal Transduction Research. 22: 345-56. PMID 12503626 DOI: 10.1081/Rrs-120014606 |
0.773 |
|
| 2002 |
Laube B, Maksay G, Schemm R, Betz H. Modulation of glycine receptor function: a novel approach for therapeutic intervention at inhibitory synapses? Trends in Pharmacological Sciences. 23: 519-27. PMID 12413807 DOI: 10.1016/S0165-6147(02)02138-7 |
0.747 |
|
| 2002 |
Laube B. Potentiation of inhibitory glycinergic neurotransmission by Zn2+: a synergistic interplay between presynaptic P2X2 and postsynaptic glycine receptors. The European Journal of Neuroscience. 16: 1025-36. PMID 12383231 DOI: 10.1046/j.1460-9568.2002.02170.x |
0.533 |
|
| 2002 |
Maksay G, BÃró T, Laube B. Hyperekplexia mutation of glycine receptors: decreased gating efficacy with altered binding thermodynamics. Biochemical Pharmacology. 64: 285-8. PMID 12123749 DOI: 10.1016/S0006-2952(02)01111-5 |
0.488 |
|
| 2001 |
Wittekindt B, Malany S, Schemm R, Otvos L, Maccecchini ML, Laube B, Betz H. Point mutations identify the glutamate binding pocket of the N-methyl-D-aspartate receptor as major site of conantokin-G inhibition. Neuropharmacology. 41: 753-61. PMID 11640930 DOI: 10.1016/S0028-3908(01)00112-5 |
0.776 |
|
| 2001 |
Büttner C, Sadtler S, Leyendecker A, Laube B, Griffon N, Betz H, Schmalzing G. Ubiquitination precedes internalization and proteolytic cleavage of plasma membrane-bound glycine receptors. The Journal of Biological Chemistry. 276: 42978-85. PMID 11560918 DOI: 10.1074/Jbc.M102121200 |
0.701 |
|
| 2001 |
Maksay G, Laube B, Betz H. Subunit-specific modulation of glycine receptors by neurosteroids. Neuropharmacology. 41: 369-76. PMID 11522328 DOI: 10.1016/S0028-3908(01)00071-5 |
0.677 |
|
| 2000 |
Harvey RJ, Schmieden V, Von Holst A, Laube B, Rohrer H, Betz H. Glycine receptors containing the alpha4 subunit in the embryonic sympathetic nervous system, spinal cord and male genital ridge. The European Journal of Neuroscience. 12: 994-1001. PMID 10762330 DOI: 10.1046/j.1460-9568.2000.00993.x |
0.695 |
|
| 2000 |
Wittekindt B, Betz H, Laube B. Subunit-dependent inhibition of recombinant rodent N-methyl-D-aspartate receptors by a HIV-1 glycoprotein 120 derived peptide. Neuroscience Letters. 280: 151-4. PMID 10686400 DOI: 10.1016/S0304-3940(00)00775-8 |
0.757 |
|
| 2000 |
Laube B, Kuhse J, Betz H. Kinetic and mutational analysis of Zn2+ modulation of recombinant human inhibitory glycine receptors. The Journal of Physiology. 522: 215-30. PMID 10639099 DOI: 10.1111/J.1469-7793.2000.T01-1-00215.X |
0.75 |
|
| 1999 |
Kreimeyer A, Laube B, Sturgess M, Goeldner M, Foucaud B. Evaluation and biological properties of reactive ligands for the mapping of the glycine site on the N-methyl-D-aspartate (NMDA) receptor. Journal of Medicinal Chemistry. 42: 4394-404. PMID 10543883 DOI: 10.1021/Jm9910730 |
0.543 |
|
| 1999 |
Kneussel M, Brandstätter JH, Laube B, Stahl S, Müller U, Betz H. Loss of postsynaptic GABA(A) receptor clustering in gephyrin-deficient mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 9289-97. PMID 10531433 |
0.715 |
|
| 1999 |
Maksay G, Laube B, Betz H. Selective blocking effects of tropisetron and atropine on recombinant glycine receptors. Journal of Neurochemistry. 73: 802-6. PMID 10428078 DOI: 10.1046/j.1471-4159.1999.0730802.x |
0.767 |
|
| 1999 |
Betz H, Kuhse J, Schmieden V, Laube B, Kirsch J, Harvey RJ. Structure and functions of inhibitory and excitatory glycine receptors. Annals of the New York Academy of Sciences. 868: 667-76. PMID 10414351 DOI: 10.1111/j.1749-6632.1999.tb11343.x |
0.759 |
|
| 1999 |
Kreimeyer A, Laube B, Sturgess M, Goeldner M, Foucaud B. Reactive affinity probes for the mapping of the glycine-binding site of the NMDA receptor NR1 subunit. Journal of Receptor and Signal Transduction Research. 19: 547-57. PMID 10071784 DOI: 10.3109/10799899909036671 |
0.553 |
|
| 1999 |
Kins S, Kuhse J, Laube B, Betz H, Kirsch J. Incorporation of a gephyrin-binding motif targets NMDA receptors to gephyrin-rich domains in HEK 293 cells. The European Journal of Neuroscience. 11: 740-4. PMID 10051776 DOI: 10.1046/J.1460-9568.1999.00527.X |
0.782 |
|
| 1999 |
Laube B, Betz H. Purification and heterologous expression of inhibitory glycine receptors. Methods in Enzymology. 294: 260-73. PMID 9916232 DOI: 10.1016/S0076-6879(99)94016-8 |
0.688 |
|
| 1999 |
Kneussel M, Brandstätter JH, Laube B, Stahl S, Müller U, Betz H. Loss of Postsynaptic GABAA Receptor Clustering in Gephyrin-Deficient Mice The Journal of Neuroscience. 19: 9289-9297. DOI: 10.1523/Jneurosci.19-21-09289.1999 |
0.741 |
|
| 1998 |
Ivanovic A, Reiländer H, Laube B, Kuhse J. Expression and initial characterization of a soluble glycine binding domain of the N-methyl-D-aspartate receptor NR1 subunit. The Journal of Biological Chemistry. 273: 19933-7. PMID 9685327 DOI: 10.1074/Jbc.273.32.19933 |
0.801 |
|
| 1998 |
Nikolic Z, Laube B, Weber RG, Lichter P, Kioschis P, Poustka A, Mülhardt C, Becker CM. The human glycine receptor subunit alpha3. Glra3 gene structure, chromosomal localization, and functional characterization of alternative transcripts. The Journal of Biological Chemistry. 273: 19708-14. PMID 9677400 DOI: 10.1074/jbc.273.31.19708 |
0.37 |
|
| 1998 |
Honer M, Benke D, Laube B, Kuhse J, Heckendorn R, Allgeier H, Angst C, Monyer H, Seeburg PH, Betz H, Mohler H. Differentiation of glycine antagonist sites of N-methyl-D-aspartate receptor subtypes. Preferential interaction of CGP 61594 with NR1/2B receptors. The Journal of Biological Chemistry. 273: 11158-63. PMID 9556603 DOI: 10.1074/Jbc.273.18.11158 |
0.8 |
|
| 1998 |
Laube B, Kuhse J, Betz H. Evidence for a tetrameric structure of recombinant NMDA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 2954-61. PMID 9526012 |
0.791 |
|
| 1998 |
Laube B, Kuhse J, Betz H. Evidence for a Tetrameric Structure of Recombinant NMDA Receptors The Journal of Neuroscience. 18: 2954-2961. DOI: 10.1523/Jneurosci.18-08-02954.1998 |
0.807 |
|
| 1997 |
Laube B, Hirai H, Sturgess M, Betz H, Kuhse J. Molecular determinants of agonist discrimination by NMDA receptor subunits: analysis of the glutamate binding site on the NR2B subunit. Neuron. 18: 493-503. PMID 9115742 DOI: 10.1016/S0896-6273(00)81249-0 |
0.799 |
|
| 1997 |
Hirai H, Laube B, Kuhse J, Betz H. 205 Analysis of the glutamate binding site on the NR2B subunit of NMDA receptor Neuroscience Research. 28: S31. DOI: 10.1016/S0168-0102(97)90073-0 |
0.783 |
|
| 1996 |
Garcia-Guzman M, Soto F, Laube B, Stühmer W. Molecular cloning and functional expression of a novel rat heart P2X purinoceptor. Febs Letters. 388: 123-7. PMID 8690069 DOI: 10.1016/0014-5793(96)00499-1 |
0.48 |
|
| 1996 |
Hirai H, Kirsch J, Laube B, Betz H, Kuhse J. The glycine binding site of the N-methyl-D-aspartate receptor subunit NR1: identification of novel determinants of co-agonist potentiation in the extracellular M3-M4 loop region. Proceedings of the National Academy of Sciences of the United States of America. 93: 6031-6. PMID 8650214 DOI: 10.1073/Pnas.93.12.6031 |
0.741 |
|
| 1995 |
Laube B, Kuhse J, Rundström N, Kirsch J, Schmieden V, Betz H. Modulation by zinc ions of native rat and recombinant human inhibitory glycine receptors. The Journal of Physiology. 483: 613-9. PMID 7776247 DOI: 10.1113/Jphysiol.1995.Sp020610 |
0.741 |
|
| 1995 |
Laube B, Langosch D, Betz H, Schmieden V. Hyperekplexia mutations of the glycine receptor unmask the inhibitory subsite for beta-amino-acids. Neuroreport. 6: 897-900. PMID 7542038 DOI: 10.1097/00001756-199504190-00018 |
0.728 |
|
| 1994 |
Kuryatov A, Laube B, Betz H, Kuhse J. Mutational analysis of the glycine-binding site of the NMDA receptor: structural similarity with bacterial amino acid-binding proteins. Neuron. 12: 1291-300. PMID 8011339 DOI: 10.1016/0896-6273(94)90445-6 |
0.76 |
|
| 1994 |
Langosch D, Laube B, Rundström N, Schmieden V, Bormann J, Betz H. Decreased agonist affinity and chloride conductance of mutant glycine receptors associated with human hereditary hyperekplexia. The Embo Journal. 13: 4223-8. PMID 7925268 |
0.756 |
|
| 1994 |
Betz H, Kuhse J, Fischer M, Schmieden V, Laube B, Kuryatov A, Langosch D, Meyer G, Bormann J, Rundström N. Structure, diversity and synaptic localization of inhibitory glycine receptors. Journal of Physiology, Paris. 88: 243-8. PMID 7874085 DOI: 10.1016/0928-4257(94)90087-6 |
0.798 |
|
| 1994 |
Langosch D, Laube B, Rundström N, Schmieden V, Bormann J, Betz H. Decreased agonist affinity and chloride conductance of mutant glycine receptors associated with human hereditary hyperekplexia. The Embo Journal. 13: 4223-4228. DOI: 10.1002/J.1460-2075.1994.Tb06742.X |
0.775 |
|
| 1993 |
Ultsch A, Schuster CM, Laube B, Betz H, Schmitt B. Glutamate receptors of Drosophila melanogaster. Primary structure of a putative NMDA receptor protein expressed in the head of the adult fly. Febs Letters. 324: 171-7. PMID 8508917 DOI: 10.1016/0014-5793(93)81387-F |
0.756 |
|
| 1993 |
Kuhse J, Laube B, Magalei D, Betz H. Assembly of the inhibitory glycine receptor: identification of amino acid sequence motifs governing subunit stoichiometry. Neuron. 11: 1049-56. PMID 8274276 DOI: 10.1016/0896-6273(93)90218-G |
0.703 |
|
| 1993 |
Laube B, Kuryatov A, Kuhse J, Betz H. Glycine-glutamate interactions at the NMDA receptor: role of cysteine residues. Febs Letters. 335: 331-4. PMID 7903251 DOI: 10.1016/0014-5793(93)80412-N |
0.795 |
|
| 1992 |
Ultsch A, Schuster CM, Laube B, Schloss P, Schmitt B, Betz H. Glutamate receptors of Drosophila melanogaster: cloning of a kainate-selective subunit expressed in the central nervous system. Proceedings of the National Academy of Sciences of the United States of America. 89: 10484-8. PMID 1359540 DOI: 10.1073/Pnas.89.21.10484 |
0.767 |
|
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