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Jeff Hasty - Publications

Affiliations: 
Bioengineering University of California, San Diego, La Jolla, CA 
Area:
Biomedical, Genetics, General
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93 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Cooper RM, Tonooka T, Didovyk A, Hasty J. Rapid, Affordable, and Uncomplicated Production of Bacterial Cell-free Lysate. Journal of Visualized Experiments : Jove. PMID 34779438 DOI: 10.3791/62753  0.319
2020 O'Laughlin R, Jin M, Li Y, Pillus L, Tsimring LS, Hasty J, Hao N. Advances in quantitative biology methods for studying replicative aging in . Translational Medicine of Aging. 4: 151-160. PMID 33880425 DOI: 10.1016/J.Tma.2019.09.002  0.316
2020 Din MO, Martin A, Razinkov I, Csicsery N, Hasty J. Interfacing gene circuits with microelectronics through engineered population dynamics. Science Advances. 6: eaaz8344. PMID 32494744 DOI: 10.1126/Sciadv.Aaz8344  0.796
2020 Bittihn P, Didovyk A, Tsimring LS, Hasty J. Genetically engineered control of phenotypic structure in microbial colonies. Nature Microbiology. PMID 32284568 DOI: 10.1038/S41564-020-0686-0  0.445
2020 Miano A, Liao MJ, Hasty J. Inducible cell-to-cell signaling for tunable dynamics in microbial communities. Nature Communications. 11: 1193. PMID 32132536 DOI: 10.1038/S41467-020-15056-8  0.409
2020 Graham G, Csicsery N, Stasiowski E, Thouvenin G, Mather WH, Ferry M, Cookson S, Hasty J. Genome-scale transcriptional dynamics and environmental biosensing. Proceedings of the National Academy of Sciences of the United States of America. PMID 31974311 DOI: 10.1073/Pnas.1913003117  0.787
2019 Liao MJ, Din MO, Tsimring L, Hasty J. Rock-paper-scissors: Engineered population dynamics increase genetic stability. Science (New York, N.Y.). 365: 1045-1049. PMID 31488693 DOI: 10.1126/Science.Aaw0542  0.403
2019 Jin M, Li Y, O'Laughlin R, Bittihn P, Pillus L, Tsimring LS, Hasty J, Hao N. Divergent Aging of Isogenic Yeast Cells Revealed through Single-Cell Phenotypic Dynamics. Cell Systems. PMID 30852250 DOI: 10.1016/J.Cels.2019.02.002  0.373
2019 Hao N, Li Y, Jiang Y, Paxman J, O’Laughlin R, Pillus L, Tsimring L, Hasty J. WADDINGTON’S LANDSCAPE OF CELL AGING Innovation in Aging. 3: S208-S208. DOI: 10.1093/Geroni/Igz038.755  0.345
2018 Baumgartner BL, O'Laughlin R, Jin M, Tsimring LS, Hao N, Hasty J. Flavin-based metabolic cycles are integral features of growth and division in single yeast cells. Scientific Reports. 8: 18045. PMID 30575765 DOI: 10.1038/S41598-018-35936-W  0.376
2018 Bittihn P, Din MO, Tsimring LS, Hasty J. Rational engineering of synthetic microbial systems: from single cells to consortia. Current Opinion in Microbiology. 45: 92-99. PMID 29574330 DOI: 10.1016/J.Mib.2018.02.009  0.402
2017 Cooper RM, Tsimring L, Hasty J. Inter-species population dynamics enhance microbial horizontal gene transfer and spread of antibiotic resistance. Elife. 6. PMID 29091031 DOI: 10.7554/Elife.25950  0.337
2017 Li Y, Jin M, O'Laughlin R, Bittihn P, Tsimring LS, Pillus L, Hasty J, Hao N. Multigenerational silencing dynamics control cell aging. Proceedings of the National Academy of Sciences of the United States of America. 114: 11253-11258. PMID 29073021 DOI: 10.1073/Pnas.1703379114  0.364
2017 Didovyk A, Tonooka T, Tsimring L, Hasty J. Rapid and scalable preparation of bacterial lysates for cell-free gene expression. Acs Synthetic Biology. PMID 28795570 DOI: 10.1021/Acssynbio.7B00253  0.443
2017 Baumgart L, Mather W, Hasty J. Synchronized DNA cycling across a bacterial population. Nature Genetics. PMID 28692067 DOI: 10.1038/Ng.3915  0.426
2017 Scott SR, Din MO, Bittihn P, Xiong L, Tsimring LS, Hasty J. A stabilized microbial ecosystem of self-limiting bacteria using synthetic quorum-regulated lysis. Nature Microbiology. 2: 17083. PMID 28604679 DOI: 10.1038/Nmicrobiol.2017.83  0.422
2017 Bittihn P, Hasty J, Tsimring LS. Suppression of Beneficial Mutations in Dynamic Microbial Populations. Physical Review Letters. 118: 028102. PMID 28128631 DOI: 10.1103/Physrevlett.118.028102  0.312
2017 Cooper RM, Tsimring L, Hasty J. Author response: Inter-species population dynamics enhance microbial horizontal gene transfer and spread of antibiotic resistance Elife. DOI: 10.7554/Elife.25950.035  0.306
2016 Steiner PJ, Williams RJ, Hasty J, Tsimring LS. Criticality and Adaptivity in Enzymatic Networks. Biophysical Journal. 111: 1078-87. PMID 27602735 DOI: 10.1016/J.Bpj.2016.07.036  0.339
2016 Din MO, Danino T, Prindle A, Skalak M, Selimkhanov J, Allen K, Julio E, Atolia E, Tsimring LS, Bhatia SN, Hasty J. Synchronized cycles of bacterial lysis for in vivo delivery. Nature. PMID 27437587 DOI: 10.1038/Nature18930  0.79
2016 Didovyk A, Borek B, Tsimring L, Hasty J. Transcriptional regulation with CRISPR-Cas9: principles, advances, and applications. Current Opinion in Biotechnology. 40: 177-184. PMID 27344519 DOI: 10.1016/J.Copbio.2016.06.003  0.312
2016 Scott SR, Hasty J. Quorum Sensing Communication Modules for Microbial Consortia. Acs Synthetic Biology. PMID 27172092 DOI: 10.1021/Acssynbio.5B00286  0.308
2016 Hossain MA, Claggett JM, Edwards SR, Shi A, Pennebaker SL, Cheng MY, Hasty J, Johnson TL. Posttranscriptional Regulation of Gcr1 Expression and Activity Is Crucial for Metabolic Adjustment in Response to Glucose Availability. Molecular Cell. 62: 346-358. PMID 27153533 DOI: 10.1016/J.Molcel.2016.04.012  0.35
2016 Borek B, Hasty J, Tsimring L. Turing Patterning Using Gene Circuits with Gas-Induced Degradation of Quorum Sensing Molecules. Plos One. 11: e0153679. PMID 27148743 DOI: 10.1371/Journal.Pone.0153679  0.393
2015 Didovyk A, Borek B, Hasty J, Tsimring L. Orthogonal Modular Gene Repression in Escherichia coli Using Engineered CRISPR/Cas9. Acs Synthetic Biology. PMID 26390083 DOI: 10.1021/Acssynbio.5B00147  0.353
2015 Luke CS, Selimkhanov J, Baumgart L, Cohen SE, Golden SS, Cookson NA, Hasty J. A Microfluidic Platform for Long-Term Monitoring of Algae in a Dynamic Environment. Acs Synthetic Biology. PMID 26332284 DOI: 10.1021/Acssynbio.5B00094  0.78
2015 Danino T, Prindle A, Kwong GA, Skalak M, Li H, Allen K, Hasty J, Bhatia SN. Programmable probiotics for detection of cancer in urine. Science Translational Medicine. 7: 289ra84. PMID 26019220 DOI: 10.1126/Scitranslmed.Aaa3519  0.781
2015 Didovyk A, Kanakov OI, Ivanchenko MV, Hasty J, Huerta R, Tsimring L. Distributed classifier based on genetically engineered bacterial cell cultures. Acs Synthetic Biology. 4: 72-82. PMID 25349924 DOI: 10.1021/Sb500235P  0.396
2014 Mather W, Hasty J, Tsimring LS. Synchronization of degrade-and-fire oscillations via a common activator. Physical Review Letters. 113: 128102. PMID 25279645 DOI: 10.1103/Physrevlett.113.128102  0.4
2014 Cohen SE, Erb ML, Selimkhanov J, Dong G, Hasty J, Pogliano J, Golden SS. Dynamic localization of the cyanobacterial circadian clock proteins. Current Biology : Cb. 24: 1836-44. PMID 25127213 DOI: 10.1016/J.Cub.2014.07.036  0.335
2014 Menolascina F, Fiore G, Orabona E, De Stefano L, Ferry M, Hasty J, di Bernardo M, di Bernardo D. In-Vivo Real-Time Control of Protein Expression from Endogenous and Synthetic Gene Networks Plos Computational Biology. 10. PMID 24831205 DOI: 10.1371/Journal.Pcbi.1003625  0.393
2014 Prindle A, Selimkhanov J, Li H, Razinkov I, Tsimring LS, Hasty J. Rapid and tunable post-translational coupling of genetic circuits. Nature. 508: 387-91. PMID 24717442 DOI: 10.1038/Nature13238  0.796
2013 Danino T, Prindle A, Hasty J, Bhatia S. Measuring growth and gene expression dynamics of tumor-targeted S. typhimurium bacteria. Journal of Visualized Experiments : Jove. e50540. PMID 23851642 DOI: 10.3791/50540  0.782
2013 Razinkov IA, Baumgartner BL, Bennett MR, Tsimring LS, Hasty J. Measuring competitive fitness in dynamic environments. The Journal of Physical Chemistry. B. 117: 13175-81. PMID 23841812 DOI: 10.1021/Jp403162V  0.786
2013 Longo DM, Selimkhanov J, Kearns JD, Hasty J, Hoffmann A, Tsimring LS. Dual delayed feedback provides sensitivity and robustness to the NF-κB signaling module. Plos Computational Biology. 9: e1003112. PMID 23825938 DOI: 10.1371/Journal.Pcbi.1003112  0.726
2013 Mather WH, Hasty J, Tsimring LS, Williams RJ. Translational cross talk in gene networks. Biophysical Journal. 104: 2564-72. PMID 23746529 DOI: 10.1016/J.Bpj.2013.04.049  0.312
2012 Danino T, Lo J, Prindle A, Hasty J, Bhatia SN. In Vivo Gene Expression Dynamics of Tumor-Targeted Bacteria. Acs Synthetic Biology. 1: 465-470. PMID 23097750 DOI: 10.1021/Sb3000639  0.779
2012 Prindle A, Selimkhanov J, Danino T, Samayoa P, Goldberg A, Bhatia SN, Hasty J. Genetic Circuits in Salmonella typhimurium. Acs Synthetic Biology. 1: 458-464. PMID 23097749 DOI: 10.1021/Sb300060E  0.794
2012 Prindle A, Hasty J. Making gene circuits sing. Proceedings of the National Academy of Sciences of the United States of America. 109: 16758-9. PMID 23027956 DOI: 10.1073/Pnas.1214118109  0.717
2012 Kolnik M, Tsimring LS, Hasty J. Vacuum-assisted cell loading enables shear-free mammalian microfluidic culture. Lab On a Chip. 12: 4732-7. PMID 22961584 DOI: 10.1039/C2Lc40569E  0.776
2012 Mather WH, Hasty J, Tsimring LS. Fast stochastic algorithm for simulating evolutionary population dynamics. Bioinformatics (Oxford, England). 28: 1230-8. PMID 22437850 DOI: 10.1093/Bioinformatics/Bts130  0.3
2012 Prindle A, Samayoa P, Razinkov I, Danino T, Tsimring LS, Hasty J. A sensing array of radically coupled genetic 'biopixels'. Nature. 481: 39-44. PMID 22178928 DOI: 10.1038/Nature10722  0.777
2012 Selimkhanov J, Hasty J, Tsimring LS. Recent advances in single-cell studies of gene regulation. Current Opinion in Biotechnology. 23: 34-40. PMID 22154220 DOI: 10.1016/J.Copbio.2011.11.006  0.432
2012 Ferry MS, Hasty J, Cookson NA. Synthetic biology approaches to biofuel production Biofuels. 3: 9-12. DOI: 10.4155/bfs.11.151  0.743
2011 Cookson NA, Mather WH, Danino T, Mondragón-Palomino O, Williams RJ, Tsimring LS, Hasty J. Queueing up for enzymatic processing: correlated signaling through coupled degradation. Molecular Systems Biology. 7: 561. PMID 22186735 DOI: 10.1038/Msb.2011.94  0.777
2011 Baumgartner BL, Bennett MR, Ferry M, Johnson TL, Tsimring LS, Hasty J. Antagonistic gene transcripts regulate adaptation to new growth environments. Proceedings of the National Academy of Sciences of the United States of America. 108: 21087-92. PMID 22160690 DOI: 10.1073/Pnas.1111408109  0.803
2011 Mondragón-Palomino O, Danino T, Selimkhanov J, Tsimring L, Hasty J. Entrainment of a population of synthetic genetic oscillators. Science (New York, N.Y.). 333: 1315-9. PMID 21885786 DOI: 10.1126/Science.1205369  0.781
2011 Jin M, Errede B, Behar M, Mather W, Nayak S, Hasty J, Dohlman HG, Elston TC. Yeast dynamically modify their environment to achieve better mating efficiency. Science Signaling. 4: ra54. PMID 21868361 DOI: 10.1126/Scisignal.2001763  0.615
2011 Danino T, Volfson D, Bhatia SN, Tsimring L, Hasty J. In-silico patterning of vascular mesenchymal cells in three dimensions. Plos One. 6: e20182. PMID 21633504 DOI: 10.1371/Journal.Pone.0020182  0.698
2011 Ferry MS, Razinkov IA, Hasty J. Microfluidics for synthetic biology: from design to execution. Methods in Enzymology. 497: 295-372. PMID 21601093 DOI: 10.1016/B978-0-12-385075-1.00014-7  0.785
2011 Boyer D, Mather W, Mondragón-Palomino O, Orozco-Fuentes S, Danino T, Hasty J, Tsimring LS. Buckling instability in ordered bacterial colonies. Physical Biology. 8: 026008. PMID 21358041 DOI: 10.1088/1478-3975/8/2/026008  0.789
2010 Mather WH, Cookson NA, Hasty J, Tsimring LS, Williams RJ. Correlation resonance generated by coupled enzymatic processing. Biophysical Journal. 99: 3172-81. PMID 21081064 DOI: 10.1016/J.Bpj.2010.09.057  0.766
2010 Hasty J, Hoffmann A, Golden S. Systems biology of cellular rhythms: from cacophony to symphony. Current Opinion in Genetics & Development. 20: 571-3. PMID 21036033 DOI: 10.1016/J.Gde.2010.10.003  0.444
2010 Mather W, Mondragón-Palomino O, Danino T, Hasty J, Tsimring LS. Streaming instability in growing cell populations. Physical Review Letters. 104: 208101. PMID 20867071 DOI: 10.1103/Physrevlett.104.208101  0.782
2010 Zhuravel D, Fraser D, St-Pierre S, Tepliakova L, Pang WL, Hasty J, Kærn M. Phenotypic impact of regulatory noise in cellular stress-response pathways. Systems and Synthetic Biology. 4: 105-16. PMID 20805931 DOI: 10.1007/S11693-010-9055-2  0.724
2010 Prindle A, Hasty J. Biochemistry. Stochastic emergence of groupthink. Science (New York, N.Y.). 328: 987-8. PMID 20489014 DOI: 10.1126/Science.1190372  0.71
2010 Danino T, Mondragón-Palomino O, Tsimring L, Hasty J. A synchronized quorum of genetic clocks. Nature. 463: 326-30. PMID 20090747 DOI: 10.1038/Nature08753  0.81
2010 Castro-Longoria E, Ferry M, Bartnicki-Garcia S, Hasty J, Brody S. Circadian rhythms in Neurospora crassa: dynamics of the clock component frequency visualized using a fluorescent reporter. Fungal Genetics and Biology : Fg & B. 47: 332-41. PMID 20051268 DOI: 10.1016/J.Fgb.2009.12.013  0.802
2010 Cookson NA, Cookson SW, Tsimring LS, Hasty J. Cell cycle-dependent variations in protein concentration. Nucleic Acids Research. 38: 2676-81. PMID 20019065 DOI: 10.1093/Nar/Gkp1069  0.803
2010 Longo DM, Hoffmann A, Tsimring LS, Hasty J. Coherent activation of a synthetic mammalian gene network. Systems and Synthetic Biology. 4: 15-23. PMID 19757189 DOI: 10.1007/S11693-009-9044-5  0.756
2009 Cookson NA, Tsimring LS, Hasty J. The pedestrian watchmaker: genetic clocks from engineered oscillators. Febs Letters. 583: 3931-7. PMID 19903483 DOI: 10.1016/J.Febslet.2009.10.089  0.784
2009 Bennett MR, Hasty J. Microfluidic devices for measuring gene network dynamics in single cells. Nature Reviews. Genetics. 10: 628-38. PMID 19668248 DOI: 10.1038/Nrg2625  0.46
2009 Bennett MR, Hasty J. Overpowering the component problem. Nature Biotechnology. 27: 450-1. PMID 19430449 DOI: 10.1038/Nbt0509-450  0.331
2009 Mather W, Bennett MR, Hasty J, Tsimring LS. Delay-induced degrade-and-fire oscillations in small genetic circuits. Physical Review Letters. 102: 068105. PMID 19257639 DOI: 10.1103/Physrevlett.102.068105  0.404
2008 Stricker J, Cookson S, Bennett MR, Mather WH, Tsimring LS, Hasty J. A fast, robust and tunable synthetic gene oscillator. Nature. 456: 516-9. PMID 18971928 DOI: 10.1038/Nature07389  0.819
2008 Volfson D, Cookson S, Hasty J, Tsimring LS. Biomechanical ordering of dense cell populations. Proceedings of the National Academy of Sciences of the United States of America. 105: 15346-51. PMID 18832176 DOI: 10.1073/Pnas.0706805105  0.804
2008 Lu T, Ferry M, Weiss R, Hasty J. A molecular noise generator. Physical Biology. 5: 036006. PMID 18698117 DOI: 10.1088/1478-3975/5/3/036006  0.795
2008 Bennett MR, Pang WL, Ostroff NA, Baumgartner BL, Nayak S, Tsimring LS, Hasty J. Metabolic gene regulation in a dynamically changing environment. Nature. 454: 1119-22. PMID 18668041 DOI: 10.1038/Nature07211  0.794
2008 Hao N, Nayak S, Behar M, Shanks RH, Nagiec MJ, Errede B, Hasty J, Elston TC, Dohlman HG. Regulation of cell signaling dynamics by the protein kinase-scaffold Ste5. Molecular Cell. 30: 649-56. PMID 18538663 DOI: 10.1016/J.Molcel.2008.04.016  0.581
2008 Bennett MR, Hasty J. Systems biology: genome rewired. Nature. 452: 824-5. PMID 18421342 DOI: 10.1038/452824A  0.315
2007 Lu T, Shen T, Bennett MR, Wolynes PG, Hasty J. Phenotypic variability of growing cellular populations. Proceedings of the National Academy of Sciences of the United States of America. 104: 18982-7. PMID 18025471 DOI: 10.1073/Pnas.0706115104  0.341
2007 Grilly C, Stricker J, Pang WL, Bennett MR, Hasty J. A synthetic gene network for tuning protein degradation in Saccharomyces cerevisiae. Molecular Systems Biology. 3: 127. PMID 17667949 DOI: 10.1038/Msb4100168  0.744
2007 Bennett MR, Volfson D, Tsimring L, Hasty J. Transient dynamics of genetic regulatory networks. Biophysical Journal. 92: 3501-12. PMID 17350994 DOI: 10.1529/Biophysj.106.095638  0.385
2007 Bennett MR, Hasty J. A DNA methylation-based switch generates bistable gene expression. Nature Genetics. 39: 146-7. PMID 17262027 DOI: 10.1038/Ng0207-146  0.359
2006 Longo D, Hasty J. Dynamics of single-cell gene expression. Molecular Systems Biology. 2: 64. PMID 17130866 DOI: 10.1038/Msb4100110  0.772
2006 Lu T, Hasty J, Wolynes PG. Effective temperature in stochastic kinetics and gene networks. Biophysical Journal. 91: 84-94. PMID 16617067 DOI: 10.1529/Biophysj.105.074914  0.344
2006 Longo D, Hasty J. Imaging gene expression: tiny signals make a big noise. Nature Chemical Biology. 2: 181-2. PMID 16547478 DOI: 10.1038/Nchembio0406-181  0.746
2006 Guido NJ, Wang X, Adalsteinsson D, McMillen D, Hasty J, Cantor CR, Elston TC, Collins JJ. A bottom-up approach to gene regulation. Nature. 439: 856-60. PMID 16482159 DOI: 10.1038/Nature04473  0.423
2006 Volfson D, Marciniak J, Blake WJ, Ostroff N, Tsimring LS, Hasty J. Origins of extrinsic variability in eukaryotic gene expression. Nature. 439: 861-4. PMID 16372021 DOI: 10.1038/Nature04281  0.807
2006 Tsimring LS, Volfson D, Hasty J. Stochastically driven genetic circuits Chaos. 16. DOI: 10.1063/1.2209571  0.378
2005 Cookson S, Ostroff N, Pang WL, Volfson D, Hasty J. Monitoring dynamics of single-cell gene expression over multiple cell cycles. Molecular Systems Biology. 1: 2005.0024. PMID 16729059 DOI: 10.1038/Msb4100032  0.811
2005 Bratsun D, Volfson D, Tsimring LS, Hasty J. Delay-induced stochastic oscillations in gene regulation. Proceedings of the National Academy of Sciences of the United States of America. 102: 14593-8. PMID 16199522 DOI: 10.1073/Pnas.0503858102  0.392
2003 Isaacs FJ, Hasty J, Cantor CR, Collins JJ. Prediction and measurement of an autoregulatory genetic module. Proceedings of the National Academy of Sciences of the United States of America. 100: 7714-9. PMID 12808135 DOI: 10.1073/Pnas.1332628100  0.445
2003 Tegner J, Yeung MK, Hasty J, Collins JJ. Reverse engineering gene networks: integrating genetic perturbations with dynamical modeling. Proceedings of the National Academy of Sciences of the United States of America. 100: 5944-9. PMID 12730377 DOI: 10.1073/Pnas.0933416100  0.379
2002 Hasty J. Design then mutate. Proceedings of the National Academy of Sciences of the United States of America. 99: 16516-8. PMID 12486244 DOI: 10.1073/Pnas.012694899  0.403
2002 Hasty J, McMillen D, Collins JJ. Engineered gene circuits. Nature. 420: 224-30. PMID 12432407 DOI: 10.1038/Nature01257  0.441
2002 Hasty J, Collins JJ. Translating the noise. Nature Genetics. 31: 13-4. PMID 11984558 DOI: 10.1038/Ng0502-13  0.308
2002 Hasty J, Dolnik M, Rottschäfer V, Collins JJ. Synthetic gene network for entraining and amplifying cellular oscillations. Physical Review Letters. 88: 148101. PMID 11955179 DOI: 10.1103/Physrevlett.88.148101  0.396
2002 McMillen D, Kopell N, Hasty J, Collins JJ. Synchronizing genetic relaxation oscillators by intercell signaling. Proceedings of the National Academy of Sciences of the United States of America. 99: 679-84. PMID 11805323 DOI: 10.1073/Pnas.022642299  0.433
2001 Hasty J, Isaacs F, Dolnik M, McMillen D, Collins JJ. Designer gene networks: Towards fundamental cellular control. Chaos (Woodbury, N.Y.). 11: 207-220. PMID 12779454 DOI: 10.1063/1.1345702  0.403
2001 Hasty J, Collins JJ. Protein interactions. Unspinning the web. Nature. 411: 30-1. PMID 11333958 DOI: 10.1038/35075182  0.374
2001 Hasty J, McMillen D, Isaacs F, Collins JJ. Computational studies of gene regulatory networks: in numero molecular biology. Nature Reviews. Genetics. 2: 268-79. PMID 11283699 DOI: 10.1038/35066056  0.375
2000 Hasty J, Pradines J, Dolnik M, Collins JJ. Noise-based switches and amplifiers for gene expression. Proceedings of the National Academy of Sciences of the United States of America. 97: 2075-80. PMID 10681449 DOI: 10.1073/Pnas.040411297  0.408
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