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Matthew L. Eaton, Ph.D. - Publications

Affiliations: 
2011 Computational Biology and Bioinformatics Duke University, Durham, NC 
Area:
Bioinformatics, Molecular Biology, Computer Science, Genetics
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31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Lee H, McManus CJ, Cho DY, Eaton M, Renda F, Somma MP, Cherbas L, May G, Powell S, Zhang D, Zhan L, Resch A, Andrews J, Celniker SE, Cherbas P, et al. Correction to: DNA copy number evolution in Drosophila cell lines. Genome Biology. 20: 53. PMID 30857560 DOI: 10.1186/S13059-019-1668-5  0.621
2018 Guenther M, Lambert A, Chen M, Fiore C, Eaton M, Orlando D, Bierie B, Weinberg R, Fritz C, Olson E. Abstract P2-04-03: Epigenomic analysis of cancer stem cell (CSC)-enriched triple-negative breast cancer (TNBC) populations reveals gene regulatory circuitry and novel tumor cell vulnerabilities Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P2-04-03  0.382
2017 McKeown MR, Corces MR, Eaton ML, Fiore C, Lee E, Lopez JT, Chen MW, Smith D, Chan SM, Koenig JL, Austgen K, Guenther MG, Orlando DA, Lovén J, Fritz CC, et al. Super-Enhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML Including an RARα Dependency Targetable by SY-1425, a Potent and Selective RARα Agonist. Cancer Discovery. PMID 28729405 DOI: 10.1158/2159-8290.Cd-17-0399  0.379
2017 Fiore CM, McKeown MR, Lee E, Eaton ML, Smith D, Austgen K, Chen MW, Guenther M, Corces MR, Majeti R, Olson E, Fritz CC. Abstract PR05: SY-1425 (tamibarotene), a potent and selective RARα agonist, induces changes in the transcriptional regulatory circuit of AML cells leading to differentiation Clinical Cancer Research. 23. DOI: 10.1158/1557-3265.Hemmal17-Pr05  0.429
2017 McKeown, Fiore C, Lee E, Eaton M, Orlando D, Guenther M, Collins C, Chen M, Fritz C, Tomaso Ed. Abstract P6-11-18: A novel subgroup of estrogen receptor positive breast cancer may benefit from super-enhancer guided patient selection for retinoic acid receptor α agonist treatment Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P6-11-18  0.326
2017 McKeown MR, Lee E, Fiore C, Eaton ML, Fritz CC, Olson E. Abstract 3085: SY-1425 (tamibarotene), a selective RARα agonist, shows synergistic anti-tumor activity with hypomethylating agents in a biomarker selected subset of AML Cancer Research. 77: 3085-3085. DOI: 10.1158/1538-7445.Am2017-3085  0.384
2017 McKeown MR, Eaton ML, Fiore C, Lee E, Austgen K, Smith D, Corces MR, Majeti R, Fritz CC. Abstract 1511: AML patient clustering by super-enhancers reveals an RARA associated transcription factor signaling partner Cancer Research. 77: 1511-1511. DOI: 10.1158/1538-7445.Am2017-1511  0.388
2016 Feng J, Gan H, Eaton ML, Zhou H, Li S, Belsky JA, MacAlpine DM, Zhang Z, Li Q. Non-coding transcription is a driving force for nucleosome instability in spt16 mutant cells. Molecular and Cellular Biology. PMID 27141053 DOI: 10.1128/Mcb.00152-16  0.649
2016 McKeown MR, Fiore C, Lee E, Eaton ML, Fritz CC. Clinical Pharmacodynamic Markers and Combinations with SY1425 (tamibarotene) in a Genomically-Defined Subset of Non-APL AML Blood. 128: 2898-2898. DOI: 10.1182/Blood.V128.22.2898.2898  0.404
2016 Fiore C, McKeown MR, Lee E, Eaton ML, Fritz CC. SY1425 (tamibarotene) Induces Profound Transcriptional Changes in AML Tumors with High Retinoic Acid Receptor Alpha Blood. 128: 1523-1523. DOI: 10.1182/Blood.V128.22.1523.1523  0.458
2015 Chibnik LB, Yu L, Eaton ML, Srivastava G, Schneider JA, Kellis M, Bennett DA, De Jager PL. Alzheimer's loci: epigenetic associations and interaction with genetic factors. Annals of Clinical and Translational Neurology. 2: 636-47. PMID 26125039 DOI: 10.1002/Acn3.201  0.318
2015 Hatchi E, Skourti-Stathaki K, Ventz S, Pinello L, Yen A, Kamieniarz-Gdula K, Dimitrov S, Pathania S, McKinney KM, Eaton ML, Kellis M, Hill SJ, Parmigiani G, Proudfoot NJ, Livingston DM. BRCA1 recruitment to transcriptional pause sites is required for R-loop-driven DNA damage repair. Molecular Cell. 57: 636-47. PMID 25699710 DOI: 10.1016/J.Molcel.2015.01.011  0.415
2015 Kundaje A, Meuleman W, Ernst J, Bilenky M, Yen A, Heravi-Moussavi A, Kheradpour P, Zhang Z, Wang J, Ziller MJ, Amin V, Whitaker JW, Schultz MD, Ward LD, ... ... Eaton ML, et al. Integrative analysis of 111 reference human epigenomes. Nature. 518: 317-30. PMID 25693563 DOI: 10.1038/Nature14248  0.404
2015 Guenther MG, Orlando DA, Eaton ML, Collins CA, Chen MW, Solanki S, Loven J, Fritz CC, Olson ER. Abstract P1-06-04: Super-enhancer analysis defines breast cancer subtype and identifies tumor dependencies Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P1-06-04  0.363
2015 Collins C, Chen MW, Eaton M, Orlando D, McKeown M, Fritz C, Olson E, Guenther M. Abstract 3837: Super-enhancers define breast cancer subclasses and identify novel tumor cell vulnerabilities Cancer Research. 75: 3837-3837. DOI: 10.1158/1538-7445.Am2015-3837  0.367
2015 Eaton M, Corces-Zimmerman R, Lopez J, Fritz C, Olson E, Majeti R, Loven J. Abstract 2212: Super-enhancer landscapes specify molecular subtypes and novel targets in acute myeloid leukemia Cancer Research. 75: 2212-2212. DOI: 10.1158/1538-7445.Am2015-2212  0.419
2014 Lee H, McManus CJ, Cho DY, Eaton M, Renda F, Somma MP, Cherbas L, May G, Powell S, Zhang D, Zhan L, Resch A, Andrews J, Celniker SE, Cherbas P, et al. DNA copy number evolution in Drosophila cell lines. Genome Biology. 15: R70. PMID 25262759 DOI: 10.1186/Gb-2014-15-8-R70  0.65
2014 De Jager PL, Srivastava G, Lunnon K, Burgess J, Schalkwyk LC, Yu L, Eaton ML, Keenan BT, Ernst J, McCabe C, Tang A, Raj T, Replogle J, Brodeur W, Gabriel S, et al. Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci. Nature Neuroscience. 17: 1156-63. PMID 25129075 DOI: 10.1038/Nn.3786  0.339
2014 Corces-Zimmerman MR, Eaton M, Lopez J, Ke N, Fritz C, Olson E, Majeti R, Loven J. Discovery and Characterization of Super-Enhancer-Associated Dependencies in Acute Myeloid Leukemia Blood. 124: 3539-3539. DOI: 10.1182/Blood.V124.21.3539.3539  0.416
2012 Sher N, Bell GW, Li S, Nordman J, Eng T, Eaton ML, Macalpine DM, Orr-Weaver TL. Developmental control of gene copy number by repression of replication initiation and fork progression. Genome Research. 22: 64-75. PMID 22090375 DOI: 10.1101/Gr.126003.111  0.697
2012 De Jager P, Srivastava G, Eaton M, Chibnik L, Kellis M, Bennett D. Genome-Wide Exploration of DNA Methylation in the Aging Brain and Its Relation to Alzheimer's Disease (P05.070) Neurology. 78: P05.070-P05.070. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P05.070  0.347
2012 Jager PD, Srivastava G, Eaton M, Chibnik L, Keenan B, Zou F, Song H, Younkin C, Younkin S, Ertekin-Taner N, Bernstein B, Meissner A, Kellis M, Bennett D. Genome-wide exploration of DNA methylation in the aging brain and its relation to Alzheimer's disease Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.1829  0.346
2012 Keenan B, Srivastava G, Eaton M, Schneider J, Chibnik L, Meissner A, Kellis M, Bennett D, Jager PD. The role of DNA methylation in Alzheimer's susceptibility genes with Alzheimer's disease phenotypes Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.1203  0.326
2011 Nègre N, Brown CD, Ma L, Bristow CA, Miller SW, Wagner U, Kheradpour P, Eaton ML, Loriaux P, Sealfon R, Li Z, Ishii H, Spokony RF, Chen J, Hwang L, et al. A cis-regulatory map of the Drosophila genome. Nature. 471: 527-31. PMID 21430782 DOI: 10.1038/Nature09990  0.68
2011 Eaton ML, Prinz JA, MacAlpine HK, Tretyakov G, Kharchenko PV, MacAlpine DM. Chromatin signatures of the Drosophila replication program. Genome Research. 21: 164-74. PMID 21177973 DOI: 10.1101/Gr.116038.110  0.704
2010 Roy S, Ernst J, Kharchenko PV, Kheradpour P, Negre N, Eaton ML, Landolin JM, Bristow CA, Ma L, Lin MF, Washietl S, Arshinoff BI, Ay F, Meyer PE, et al. Identification of functional elements and regulatory circuits by Drosophila modENCODE. Science (New York, N.Y.). 330: 1787-97. PMID 21177974 DOI: 10.1126/Science.1198374  0.682
2010 Dwyer MA, Joseph JD, Wade HE, Eaton ML, Kunder RS, Kazmin D, Chang CY, McDonnell DP. WNT11 expression is induced by estrogen-related receptor alpha and beta-catenin and acts in an autocrine manner to increase cancer cell migration. Cancer Research. 70: 9298-308. PMID 20870744 DOI: 10.1158/0008-5472.Can-10-0226  0.314
2010 Müller P, Park S, Shor E, Huebert DJ, Warren CL, Ansari AZ, Weinreich M, Eaton ML, MacAlpine DM, Fox CA. The conserved bromo-adjacent homology domain of yeast Orc1 functions in the selection of DNA replication origins within chromatin Genes and Development. 24: 1418-1433. PMID 20595233 DOI: 10.1101/Gad.1906410  0.663
2010 Eaton ML, Galani K, Kang S, Bell SP, MacAlpine DM. Conserved nucleosome positioning defines replication origins Genes and Development. 24: 748-753. PMID 20351051 DOI: 10.1101/Gad.1913210  0.659
2010 Wade HE, Kobayashi S, Eaton ML, Jansen MS, Lobenhofer EK, Lupien M, Geistlinger TR, Zhu W, Nevins JR, Brown M, Otteson DC, McDonnell DP. Multimodal regulation of E2F1 gene expression by progestins. Molecular and Cellular Biology. 30: 1866-77. PMID 20123965 DOI: 10.1128/Mcb.01060-09  0.404
2006 Weir M, Eaton M, Rice M. Challenging the spliceosome machine. Genome Biology. 7: R3. PMID 16507135 DOI: 10.1186/Gb-2006-7-1-R3  0.363
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