John R. O'Kusky - Publications

Affiliations: 
University of British Columbia, Vancouver, Vancouver, BC, Canada 
Area:
methyl mercury toxicity

40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 O'Kusky J, Ye P. Neurodevelopmental effects of insulin-like growth factor signaling Frontiers in Neuroendocrinology. 33: 230-251. PMID 22710100 DOI: 10.1016/j.yfrne.2012.06.002  1
2012 Hu Q, Lee SY, O'Kusky JR, Ye P. Signalling through the type 1 insulin-like growth factor receptor (IGF1R) interacts with canonical Wnt signalling to promote neural proliferation in developing brain. Asn Neuro. 4. PMID 22625652 DOI: 10.1042/AN20120009  1
2011 Schutz PW, Wong PKH, O'Kusky J, Innis SM, Stockler S. Effects of d-3-hydroxybutyrate treatment on hypoglycemic coma in rat pups Experimental Neurology. 227: 180-187. PMID 21056562 DOI: 10.1016/j.expneurol.2010.10.013  1
2009 Liu W, Ye P, O'Kusky JR, D'Ercole AJ. Type 1 insulin-like growth factor receptor signaling is essential for the development of the hippocampal formation and dentate gyrus. Journal of Neuroscience Research. 87: 2821-32. PMID 19437543 DOI: 10.1002/jnr.22129  1
2008 Wu X, Vallance BA, Boyer L, Bergstrom KS, Walker J, Madsen K, O'Kusky JR, Buchan AM, Jacobson K. Saccharomyces boulardii ameliorates Citrobacter rodentium-induced colitis through actions on bacterial virulence factors. American Journal of Physiology. Gastrointestinal and Liver Physiology. 294: G295-306. PMID 18032474 DOI: 10.1152/ajpgi.00173.2007  1
2007 Flores J, Cepeda IL, Cornfeldt ML, O'Kusky JR, Doudet DJ. Characterization and survival of long-term implants of human retinal pigment epithelial cells attached to gelatin microcarriers in a model of Parkinson disease. Journal of Neuropathology and Experimental Neurology. 66: 585-96. PMID 17620984 DOI: 10.1097/nen.0b013e318093e53a  1
2007 Cepeda IL, Flores J, Cornfeldt ML, O'Kusky JR, Doudet DJ. Human retinal pigment epithelial cell implants ameliorate motor deficits in two rat models of Parkinson disease. Journal of Neuropathology and Experimental Neurology. 66: 576-84. PMID 17620983 DOI: 10.1097/nen.0b013e318093e521  1
2007 Hodge RD, D'Ercole AJ, O'Kusky JR. Insulin-like growth factor-I (IGF-I) inhibits neuronal apoptosis in the developing cerebral cortex in vivo. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 25: 233-41. PMID 17459648 DOI: 10.1016/j.ijdevneu.2007.03.004  1
2006 Coti Bertrand P, O'Kusky JR, Innis SM. Maternal dietary (n-3) fatty acid deficiency alters neurogenesis in the embryonic rat brain. The Journal of Nutrition. 136: 1570-5. PMID 16702323  1
2005 Hodge RD, D'Ercole AJ, O'Kusky JR. Increased expression of insulin-like growth factor-I (IGF-I) during embryonic development produces neocortical overgrowth with differentially greater effects on specific cytoarchitectonic areas and cortical layers. Brain Research. Developmental Brain Research. 154: 227-37. PMID 15707676 DOI: 10.1016/j.devbrainres.2004.10.016  1
2004 Hodge RD, D'Ercole AJ, O'Kusky JR. Insulin-like growth factor-I accelerates the cell cycle by decreasing G1 phase length and increases cell cycle reentry in the embryonic cerebral cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 10201-10. PMID 15537892 DOI: 10.1523/JNEUROSCI.3246-04.2004  1
2004 Popken GJ, Hodge RD, Ye P, Zhang J, Ng W, O'Kusky JR, D'Ercole AJ. In vivo effects of insulin-like growth factor-I (IGF-I) on prenatal and early postnatal development of the central nervous system. The European Journal of Neuroscience. 19: 2056-68. PMID 15090033 DOI: 10.1111/j.0953-816X.2004.03320.x  1
2003 O'Kusky JR, Ye P, D'Ercole AJ. Increased expression of insulin-like growth factor I augments the progressive phase of synaptogenesis without preventing synapse elimination in the hypoglossal nucleus. The Journal of Comparative Neurology. 464: 382-91. PMID 12900931 DOI: 10.1002/cne.10794  1
2002 D'Ercole AJ, Ye P, O'Kusky JR. Mutant mouse models of insulin-like growth factor actions in the central nervous system. Neuropeptides. 36: 209-20. PMID 12359511 DOI: 10.1054/npep.2002.0893  1
2000 O'Kusky JR, Ye P, D'Ercole AJ. Insulin-like growth factor-I promotes neurogenesis and synaptogenesis in the hippocampal dentate gyrus during postnatal development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 8435-42. PMID 11069951  1
1999 Dentremont KD, Ye P, D'Ercole AJ, O'Kusky JR. Increased insulin-like growth factor-I (IGF-I) expression during early postnatal development differentially increases neuron number and growth in medullary nuclei of the mouse. Brain Research. Developmental Brain Research. 114: 135-41. PMID 10209251 DOI: 10.1016/S0165-3806(99)00024-3  1
1999 O'Kusky JR, Nasir J, Cicchetti F, Parent A, Hayden MR. Neuronal degeneration in the basal ganglia and loss of pallido-subthalamic synapses in mice with targeted disruption of the Huntington's disease gene. Brain Research. 818: 468-79. PMID 10082833 DOI: 10.1016/S0006-8993(98)01312-2  1
1998 O'Kusky JR. Postnatal changes in the numerical density and total number of asymmetric and symmetric synapses in the hypoglossal nucleus of the rat. Brain Research. Developmental Brain Research. 108: 179-91. PMID 9693795 DOI: 10.1016/S0165-3806(98)00048-0  1
1997 Wellington CL, Brinkman RR, O'Kusky JR, Hayden MR. Toward understanding the molecular pathology of Huntington's disease. Brain Pathology (Zurich, Switzerland). 7: 979-1002. PMID 9217979  1
1996 O'Kusky JR, Akers MA, Vinters HV. Synaptogenesis in hemimegalencephaly: the numerical density of asymmetric and symmetric synapses in the cerebral cortex. Acta Neuropathologica. 92: 156-63. PMID 8841661 DOI: 10.1007/s004010050503  1
1996 Goldberg YP, Kalchman MA, Metzler M, Nasir J, Zeisler J, Graham R, Koide HB, O'Kusky J, Sharp AH, Ross CA, Jirik F, Hayden MR. Absence of disease phenotype and intergenerational stability of the CAG repeat in transgenic mice expressing the human Huntington disease transcript Human Molecular Genetics. 5: 177-185. PMID 8824873 DOI: 10.1093/hmg/5.2.177  1
1995 Nasir J, Floresco SB, O'Kusky JR, Diewert VM, Richman JM, Zeisler J, Borowski A, Marth JD, Phillips AG, Hayden MR. Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes. Cell. 81: 811-23. PMID 7774020 DOI: 10.1016/0092-8674(95)90542-1  1
1995 O'Kusky JR, Kozuki DE, Norman MG. Sudden infant death syndrome: postnatal changes in the volumes of the pons, medulla and cervical spinal cord. Journal of Neuropathology and Experimental Neurology. 54: 570-80. PMID 7602330  1
1991 O'Kusky JR, Boyes BE, Walker DG, McGeer EG. Cytomegalovirus infection of the developing brain alters catecholamine and indoleamine metabolism. Brain Research. 559: 322-30. PMID 1724407 DOI: 10.1016/0006-8993(91)90019-R  1
1989 O'Kusky JR, McGeer EG. Methylmercury-induced movement and postural disorders in developing rat: high-affinity uptake of choline, glutamate, and gamma-aminobutyric acid in the cerebral cortex and caudate-putamen. Journal of Neurochemistry. 53: 999-1006. PMID 2570131  1
1989 Boyes BE, Walker DG, McGeer EG, O'Kusky JR. Increased uric acid in the developing brain and spinal cord following cytomegalovirus infection. Journal of Neurochemistry. 53: 1719-23. PMID 2553863  1
1989 Walker DG, O'Kusky JR, McGeer PL. In situ hybridization analysis for herpes simplex virus nucleic acids in Alzheimer disease. Alzheimer Disease and Associated Disorders. 3: 123-31. PMID 2551348  1
1988 O'Kusky JR, Boyes BE, McGeer EG. Methylmercury-induced movement and postural disorders in developing rat: regional analysis of brain catecholamines and indoleamines. Brain Research. 439: 138-46. PMID 3359179 DOI: 10.1016/0006-8993(88)91470-9  1
1988 O'Kusky J, Strauss E, Kosaka B, Wada J, Li D, Druhan M, Petrie J. The corpus callosum is larger with right-hemisphere cerebral speech dominance Annals of Neurology. 24: 379-383. PMID 3228272  1
1988 O'Kusky JR, Radke JM, Vincent SR. Methylmercury-induced movement and postural disorders in developing rat: loss of somatostatin-immunoreactive interneurons in the striatum. Brain Research. 468: 11-23. PMID 2897869 DOI: 10.1016/0165-3806(88)90003-X  1
1988 Dyck RH, O'Kusky JR. Increased cytochrome oxidase activity of mesencephalic neurons in developing rats displaying methylmercury-induced movement and postural disorders. Neuroscience Letters. 89: 271-6. PMID 2843796 DOI: 10.1016/0304-3940(88)90538-1  1
1985 O'Kusky JR. Synapse elimination in the developing visual cortex: a morphometric analysis in normal and dark-reared cats. Brain Research. 354: 81-91. PMID 4041921 DOI: 10.1016/0165-3806(85)90071-9  1
1985 O'Kusky JR, McGeer EG. Methylmercury poisoning of the developing nervous system in the rat: decreased activity of glutamic acid decarboxylase in cerebral cortex and neostriatum. Brain Research. 353: 299-306. PMID 4041911 DOI: 10.1016/0165-3806(85)90219-6  1
1985 O'Kusky J. Synaptic degeneration in rat visual cortex after neonatal administration of methylmercury Experimental Neurology. 89: 32-47. PMID 4007114 DOI: 10.1016/0014-4886(85)90263-8  1
1985 McGeer EG, Norman M, Boyes B, O'Kusky J, Suzuki J, McGeer PL. Acetylcholine and aromatic amine systems in postmortem brain of an infant with Down's syndrome Experimental Neurology. 87: 557-570. PMID 2857653 DOI: 10.1016/0014-4886(85)90184-0  1
1983 O'Kusky J. Methylmercury poisoning of the developing nervous system: Morphological changes in neuronal mitochondria Acta Neuropathologica. 61: 116-122. PMID 6637395 DOI: 10.1007/BF00697390  1
1982 O'Kusky J, Colonnier M. Postnatal changes in the number of astrocytes, oligodendrocytes, and microglia in the visual cortex (area 17) of the macaque monkey: A stereologial analysis in normal and monocularly deprived animals Journal of Comparative Neurology. 210: 307-315. PMID 7142445  1
1982 O'Kusky J, Colonnier M. Postnatal changes in the number of neurons and synapses in the visual cortex (area 17) of the macaque monkey: A stereological analysis in normal and monocularly deprived animals Journal of Comparative Neurology. 210: 291-306. PMID 7142444  1
1982 O'Kusky J, Colonnier M. A laminar analysis of the number of neurons, glia, and synapses in the visual cortex (area 17) of adult macaque monkeys Journal of Comparative Neurology. 210: 278-290. PMID 7142443  1
1981 Colonnier M, O'Kusky J. A review of the number of neurons and synapses in the visual cortex of different species | LE NOMBRE DE NEURONES ET DE SYNAPSES DANS LE CORTEX VISUEL DE DIFFERENTES ESPECES Revue Canadienne De Biologie. 40: 91-99. PMID 7244322  1
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