Manus Ward - Publications

Affiliations: 
Royal College of Surgeons of Ireland, Dublin, County Dublin, Ireland 
Area:
Neurotoxicity
Website:
http://www.rcsi.ie/researchdb/research_piprofile.jsp?uid=46

18 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Weisová P, Anilkumar U, Ryan C, Concannon CG, Prehn JH, Ward MW. 'Mild mitochondrial uncoupling' induced protection against neuronal excitotoxicity requires AMPK activity. Biochimica Et Biophysica Acta. 1817: 744-53. PMID 22336583 DOI: 10.1016/j.bbabio.2012.01.016  0.436
2012 D'Orsi B, Bonner H, Tuffy LP, Düssmann H, Woods I, Courtney MJ, Ward MW, Prehn JH. Calpains are downstream effectors of bax-dependent excitotoxic apoptosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 1847-58. PMID 22302823 DOI: 10.1523/Jneurosci.2345-11.2012  0.713
2011 Tsuchiya T, Bonner HP, Engel T, Woods I, Matsushima S, Ward MW, Taki W, Henshall DC, Concannon CG, Prehn JH. Bcl-2 homology domain 3-only proteins Puma and Bim mediate the vulnerability of CA1 hippocampal neurons to proteasome inhibition in vivo. The European Journal of Neuroscience. 33: 401-8. PMID 21198986 DOI: 10.1111/j.1460-9568.2010.07538.x  0.523
2011 Weisová P, Dávila D, Tuffy LP, Ward MW, Concannon CG, Prehn JH. Role of 5'-adenosine monophosphate-activated protein kinase in cell survival and death responses in neurons. Antioxidants & Redox Signaling. 14: 1863-76. PMID 20712420 DOI: 10.1089/Ars.2010.3544  0.407
2010 Tuffy LP, Concannon CG, D'Orsi B, King MA, Woods I, Huber HJ, Ward MW, Prehn JH. Characterization of Puma-dependent and Puma-independent neuronal cell death pathways following prolonged proteasomal inhibition. Molecular and Cellular Biology. 30: 5484-501. PMID 20921277 DOI: 10.1128/Mcb.00575-10  0.304
2010 Zhdanov AV, Ward MW, Taylor CT, Souslova EA, Chudakov DM, Prehn JH, Papkovsky DB. Extracellular calcium depletion transiently elevates oxygen consumption in neurosecretory PC12 cells through activation of mitochondrial Na+/Ca2+ exchange. Biochimica Et Biophysica Acta. 1797: 1627-37. PMID 20550942 DOI: 10.1016/J.Bbabio.2010.06.006  0.502
2010 Bonner HP, Concannon CG, Bonner C, Woods I, Ward MW, Prehn JH. Differential expression patterns of Puma and Hsp70 following proteasomal stress in the hippocampus are key determinants of neuronal vulnerability. Journal of Neurochemistry. 114: 606-16. PMID 20477911 DOI: 10.1111/j.1471-4159.2010.06790.x  0.56
2010 Ward MW, Concannon CG, Whyte J, Walsh CM, Corley B, Prehn JH. The amyloid precursor protein intracellular domain(AICD) disrupts actin dynamics and mitochondrial bioenergetics. Journal of Neurochemistry. 113: 275-84. PMID 20405578 DOI: 10.1111/j.1471-4159.2010.06615.x  0.304
2010 Concannon CG, Tuffy LP, Weisová P, Bonner HP, Dávila D, Bonner C, Devocelle MC, Strasser A, Ward MW, Prehn JH. AMP kinase-mediated activation of the BH3-only protein Bim couples energy depletion to stress-induced apoptosis. The Journal of Cell Biology. 189: 83-94. PMID 20351066 DOI: 10.1083/Jcb.200909166  0.311
2009 Weisová P, Concannon CG, Devocelle M, Prehn JH, Ward MW. Regulation of glucose transporter 3 surface expression by the AMP-activated protein kinase mediates tolerance to glutamate excitation in neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 2997-3008. PMID 19261894 DOI: 10.1523/JNEUROSCI.0354-09.2009  0.498
2008 Murphy N, Bonner HP, Ward MW, Murphy BM, Prehn JH, Henshall DC. Depletion of 14-3-3 zeta elicits endoplasmic reticulum stress and cell death, and increases vulnerability to kainate-induced injury in mouse hippocampal cultures. Journal of Neurochemistry. 106: 978-88. PMID 18466333 DOI: 10.1111/j.1471-4159.2008.05447.x  0.387
2008 Concannon CG, Ward MW, Bonner HP, Kuroki K, Tuffy LP, Bonner CT, Woods I, Engel T, Henshall DC, Prehn JH. NMDA receptor-mediated excitotoxic neuronal apoptosis in vitro and in vivo occurs in an ER stress and PUMA independent manner. Journal of Neurochemistry. 105: 891-903. PMID 18088354 DOI: 10.1111/J.1471-4159.2007.05187.X  0.501
2008 Zhdanov AV, Ward MW, Prehn JH, Papkovsky DB. Dynamics of intracellular oxygen in PC12 Cells upon stimulation of neurotransmission. The Journal of Biological Chemistry. 283: 5650-61. PMID 18086678 DOI: 10.1074/Jbc.M706439200  0.4
2007 Ward MW, Huber HJ, Weisová P, Düssmann H, Nicholls DG, Prehn JH. Mitochondrial and plasma membrane potential of cultured cerebellar neurons during glutamate-induced necrosis, apoptosis, and tolerance. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 8238-49. PMID 17670970 DOI: 10.1523/JNEUROSCI.1984-07.2007  0.536
2007 König HG, Rehm M, Gudorf D, Krajewski S, Gross A, Ward MW, Prehn JH. Full length Bid is sufficient to induce apoptosis of cultured rat hippocampal neurons. Bmc Cell Biology. 8: 7. PMID 17326836 DOI: 10.1186/1471-2121-8-7  0.399
2006 Ward MW, Rehm M, Duessmann H, Kacmar S, Concannon CG, Prehn JH. Real time single cell analysis of Bid cleavage and Bid translocation during caspase-dependent and neuronal caspase-independent apoptosis. The Journal of Biological Chemistry. 281: 5837-44. PMID 16407197 DOI: 10.1074/jbc.M511562200  0.364
2005 Kushnareva YE, Wiley SE, Ward MW, Andreyev AY, Murphy AN. Excitotoxic injury to mitochondria isolated from cultured neurons. The Journal of Biological Chemistry. 280: 28894-902. PMID 15932874 DOI: 10.1074/jbc.M503090200  0.741
2004 Ward MW, Kögel D, Prehn JH. Neuronal apoptosis: BH3-only proteins the real killers? Journal of Bioenergetics and Biomembranes. 36: 295-8. PMID 15377860 DOI: 10.1023/B:JOBB.0000041756.23918.11  0.451
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