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Jeffrey M. Friedman - Related publications

Rockefeller University, New York, NY, United States 
molecular mechanisms that regulate food intake and body weight
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Jhun J, Woo JS, Lee SH, Jeong JH, Jung K, Hur W, Lee SY, Ryu JY, Moon YM, Jung YJ, Song KY, Chang K, Yoon SK, Park SH, Cho ML. GRIM19 Impedes Obesity by Regulating Inflammatory White Fat Browning and Promoting Th17/Treg Balance. Cells. 10. PMID 33467683 DOI: 10.3390/cells10010162   
2021 Sivaprakasam S, Sikder MOF, Ramalingam L, Kaur G, Dufour JM, Moustaid-Moussa N, Wachtel MS, Ganapathy V. SLC6A14 deficiency is linked to obesity, fatty liver, and metabolic syndrome but only under conditions of a high-fat diet. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 166087. PMID 33513428 DOI: 10.1016/j.bbadis.2021.166087   
2021 Kunath A, Weiner J, Krause K, Rehders M, Pejkovska A, Gericke M, Biniossek ML, Dommel S, Kern M, Ribas-Latre A, Schilling O, Brix K, Stumvoll M, Klöting N, Heiker JT, et al. Role of Kallikrein 7 in Body Weight and Fat Mass Regulation. Biomedicines. 9. PMID 33572949 DOI: 10.3390/biomedicines9020131   
2021 Murakami S, Hirazawa C, Ohya T, Yoshikawa R, Mizutani T, Ma N, Moriyama M, Ito T, Matsuzaki C. The Edible Brown Seaweed (Turner) C. Agardh Ameliorates High-Fat Diet-Induced Obesity, Diabetes, and Hepatic Steatosis in Mice. Nutrients. 13. PMID 33567531 DOI: 10.3390/nu13020551   
2021 van der Zande HJP, Gonzalez MA, de Ruiter K, Wilbers RHP, García-Tardón N, van Huizen M, van Noort K, Pelgrom LR, Lambooij JM, Zawistowska-Deniziak A, Otto F, Ozir-Fazalalikhan A, van Willigen D, Welling M, Poles J, et al. The helminth glycoprotein omega-1 improves metabolic homeostasis in obese mice through type 2 immunity-independent inhibition of food intake. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21331. PMID 33476078 DOI: 10.1096/fj.202001973R   
2021 Mizoguchi A, Banno R, Sun R, Yaginuma H, Taki K, Kobayashi T, Sugiyama M, Tsunekawa T, Onoue T, Takagi H, Hagiwara D, Ito Y, Iwama S, Suga H, Arima H. High-fat feeding causes inflammation and insulin resistance in the ventral tegmental area in mice. Neuroscience. PMID 33609637 DOI: 10.1016/j.neuroscience.2021.02.009   
2021 Tsai HP, Hou PH, Mao FC, Chang CC, Yang WC, Wu CF, Liao HJ, Lin TC, Chou LS, Hsiao LW, Chang GR. Risperidone Exacerbates Glucose Intolerance, Nonalcoholic Fatty Liver Disease, and Renal Impairment in Obese Mice. International Journal of Molecular Sciences. 22. PMID 33401717 DOI: 10.3390/ijms22010409   
2021 Kwak CS, Kim MJ, Park S, Kim IG. Antioxidant Activity of Sprouts Extracts Is Correlated with Their Anti-Obesity and Anti-Inflammatory Effects in High-Fat Diet-Fed Mice. Evidence-Based Complementary and Alternative Medicine : Ecam. 2021: 8367802. PMID 33643424 DOI: 10.1155/2021/8367802   
2021 Choi HJ, Kim HY, Park KS. Antiobesity Effect of a Novel Herbal Formulation in High-Fat Diet-Induced Obese Mice. Evidence-Based Complementary and Alternative Medicine : Ecam. 2021: 6612996. PMID 33628302 DOI: 10.1155/2021/6612996   
2021 Jo A, Kim M, Kim JI, Ha J, Hwang YS, Nam H, Hwang I, Kim JB, Park SB. Phenotypic discovery of SB1501, an anti-obesity agent via modulating mitochondrial activities. Chemmedchem. PMID 33538065 DOI: 10.1002/cmdc.202100062   
2021 Tang Q, Liu Q, Yang X, Wu T, Huang C, Zhang J, Zhang Z, Zhang G, Zhao Y, Zhou J, Huang H, Xia Y, Yan J, Li Y, He J. Sirtuin 6 supra-physiological overexpression in hypothalamic pro-opiomelanocortin neurons promotes obesity via the hypothalamus-adipose axis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21408. PMID 33583107 DOI: 10.1096/fj.202002607   
2021 Lee JY, Kim TY, Kang H, Oh J, Park JW, Kim SC, Kim M, Apostolidis E, Kim YC, Kwon YI. Anti-Obesity and Anti-Adipogenic Effects of Chitosan Oligosaccharide (GO2KA1) in SD Rats and in 3T3-L1 Preadipocytes Models. Molecules (Basel, Switzerland). 26. PMID 33440605 DOI: 10.3390/molecules26020331   
2021 Chung SI, Kang MY. Oral Administration of Germinated, Pigmented, Giant Embryo Rice ( L. cv. Keunnunjami) Extract Improves the Lipid and Glucose Metabolisms in High-Fat Diet-Fed Mice. Oxidative Medicine and Cellular Longevity. 2021: 8829778. PMID 33552386 DOI: 10.1155/2021/8829778   
2021 Tangseefa P, Martin SK, Chin PY, Breen J, Mah CY, Baldock PA, Wittert GA, Page AJ, Proud CG, Fitter S, Zannettino ACW. The mTORC1 complex in pre-osteoblasts regulates whole-body energy metabolism independently of osteocalcin. Bone Research. 9: 10. PMID 33551450 DOI: 10.1038/s41413-020-00123-z   
2021 Cai X, Feng Y, Xu M, Yu C, Xie W. is required in part for the anti-obesity effect of constitutive androstane receptor (CAR). Acta Pharmaceutica Sinica. B. 11: 434-441. PMID 33643822 DOI: 10.1016/j.apsb.2020.08.015   
2021 Vundavilli H, Tripathi LP, Datta A, Mizuguchi K. Network Modeling and Inference of Peroxisome Proliferator-Activated Receptor Pathway in High fat diet-linked Obesity. Journal of Theoretical Biology. 110647. PMID 33640449 DOI: 10.1016/j.jtbi.2021.110647   
2021 Dodd GT, Kim SJ, Méquinion M, Xirouchaki CE, Brüning JC, Andrews ZB, Tiganis T. Insulin signaling in AgRP neurons regulates meal size to limit glucose excursions and insulin resistance. Science Advances. 7. PMID 33637536 DOI: 10.1126/sciadv.abf4100   
2021 Cheng X, Shihabudeen Haider Ali MS, Moran M, Viana MP, Schlichte SL, Zimmerman MC, Khalimonchuk O, Feinberg MW, Sun X. Long non-coding RNA Meg3 deficiency impairs glucose homeostasis and insulin signaling by inducing cellular senescence of hepatic endothelium in obesity. Redox Biology. 40: 101863. PMID 33508742 DOI: 10.1016/j.redox.2021.101863   
2021 Liu Q, Li L, Gao L, Li C, Huan Y, Lei L, Cao H, Li L, Gao A, Liu S, Shen Z. Combination of bis (α -furancarboxylato) oxovanadium (IV) and metformin improves hepatic steatosis through downregulating inflammatory pathways in high-fat diet-induced obese C57BL/6J mice. Basic & Clinical Pharmacology & Toxicology. PMID 33599105 DOI: 10.1111/bcpt.13573   
2021 Tao L, Guo X, Xu M, Wang Y, Xie W, Chen H, Ma M, Li X. Dexmedetomidine ameliorates high-fat diet-induced nonalcoholic fatty liver disease by targeting SCD1 in obesity mice. Pharmacology Research & Perspectives. 9: e00700. PMID 33474802 DOI: 10.1002/prp2.700   
2021 Okue S, Ishikawa E, Nakahara R, Ito T, Okura T, Sakae M, Miura A, Ozaki-Masuzawa Y, Hosono T, Seki T. Fish oil suppresses obesity more potently in lean mice than in diet-induced obese mice but ameliorates steatosis in such obese mice. Bioscience, Biotechnology, and Biochemistry. 85: 421-429. PMID 33604637 DOI: 10.1093/bbb/zbaa038   
2021 Ishiyama S, Kimura M, Umihira N, Matsumoto S, Takahashi A, Nakagawa T, Wakayama T, Kishigami S, Mochizuki K. Mice derived from in vitro-αMEM cultured preimplantation embryos exhibit postprandial hyperglycemia and higher inflammatory gene expression in peripheral leukocytes. Bioscience, Biotechnology, and Biochemistry. PMID 33587104 DOI: 10.1093/bbb/zbab023   
2021 Buckley TN, Omotola O, Archer LA, Rostron CR, Kamineni EP, Llanora JD, Chalfant JM, Lei F, Slade E, Pendergast JS. High-fat feeding disrupts daily eating behavior rhythms in obesity-prone but not in obesity-resistant male inbred mouse strains. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. PMID 33626995 DOI: 10.1152/ajpregu.00150.2020   
2021 Hundahl C, Kotzbeck P, Burm HB, Christiansen SH, Torz L, Helge AW, Madsen MP, Ratner C, Serup AK, Thompson JJ, Eichmann TO, Pers TH, Woldbye DP, Piomelli D, Kiens B, et al. Hypothalamic hormone-sensitive lipase regulates appetite and energy homeostasis. Molecular Metabolism. 101174. PMID 33549847 DOI: 10.1016/j.molmet.2021.101174   
2021 Armitage EG, Barnes A, Patrick K, Bechar J, Harrison MJ, Lavery GG, Rainger GE, Buckley CD, Loftus NJ, Wilson ID, Naylor AJ. Metabolic consequences for mice lacking Endosialin: LC-MS/MS-based metabolic phenotyping of serum from C56Bl/6J Control and CD248 knock-out mice. Metabolomics : Official Journal of the Metabolomic Society. 17: 14. PMID 33462674 DOI: 10.1007/s11306-020-01764-1   
2021 Rivera K, Quiñones V, Amigo L, Santander N, Salas-Pérez F, Xavier A, Fernández-Galilea M, Carrasco G, Cabrera D, Arrese M, Busso D, Andia ME, Rigotti A. Lipoprotein receptor SR-B1 deficiency enhances adipose tissue inflammation and reduces susceptibility to hepatic steatosis during diet-induced obesity in mice. Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. 158909. PMID 33631309 DOI: 10.1016/j.bbalip.2021.158909   
2021 Latorre J, Lluch A, Ortega FJ, Gavaldà-Navarro A, Comas F, Morón-Ros S, Rodríguez A, Becerril S, Villarroya F, Frühbeck G, Ricart W, Giralt M, Fernández-Real JM, Moreno-Navarrete JM. Adipose tissue knockdown of lysozyme reduces local inflammation and improves adipogenesis in high-fat diet-fed mice. Pharmacological Research. 105486. PMID 33556481 DOI: 10.1016/j.phrs.2021.105486   
2021 An M, Park YH, Lim YH. Antiobesity and antidiabetic effects of the dairy bacterium Propionibacterium freudenreichii MJ2 in high-fat diet-induced obese mice by modulating lipid metabolism. Scientific Reports. 11: 2481. PMID 33510408 DOI: 10.1038/s41598-021-82282-5   
2021 Gu Y, Xiao X, Pan R, Zhang J, Zhao Y, Dong Y, Cui H. Lactobacillus plantarum dy-1 fermented barley extraction activates white adipocyte browning in high-fat diet-induced obese rats. Journal of Food Biochemistry. e13680. PMID 33646616 DOI: 10.1111/jfbc.13680   
2021 da Silva IV, Whalen CA, Mattie FJ, Florindo C, Huang NK, Heil SG, Neuberger T, Ross AC, Soveral G, Castro R. An Atherogenic Diet Disturbs Expression in Liver and Adipocyte Tissues of Apolipoprotein E-Deficient Mice: New Insights into an Old Model of Experimental Atherosclerosis. Biomedicines. 9. PMID 33557105 DOI: 10.3390/biomedicines9020150   
2021 Mao T, Wei Q, Zhao F, Zhang C. Short-term fasting reshapes fat tissue. Endocrine Journal. PMID 33441502 DOI: 10.1507/endocrj.EJ20-0405   
2021 Li L, Wei Y, Fang C, Liu S, Zhou F, Zhao G, Li Y, Luo Y, Guo Z, Lin W, Yang W. Exercise retards ongoing adipose tissue fibrosis in diet-induced obese mice. Endocrine Connections. PMID 33617465 DOI: 10.1530/EC-20-0643   
2021 Baek JH, Kim DH, Lee J, Kim SJ, Chun KH. Galectin-1 accelerates high-fat diet-induced obesity by activation of peroxisome proliferator-activated receptor gamma (PPARγ) in mice. Cell Death & Disease. 12: 66. PMID 33431823 DOI: 10.1038/s41419-020-03367-z   
2021 Zhang X, Xia H, Wang J, Leng R, Zhou X, Gao Q, He K, Liu D, Huang B. Effect of selenium-enriched kiwifruit on body fat reduction and liver protection in hyperlipidaemic mice. Food & Function. PMID 33532813 DOI: 10.1039/d0fo02410d   
2021 Hedges CP, Boix J, Jaiswal JK, Shetty B, Shepherd PR, Merry TL. Efficacy of Providing the PI3K p110α Inhibitor BYL719 (Alpelisib) to Middle-Aged Mice in Their Diet. Biomolecules. 11. PMID 33503847 DOI: 10.3390/biom11020150   
2021 Ahmed B, Sultana R, Greene MW. Adipose tissue and insulin resistance in obese. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 137: 111315. PMID 33561645 DOI: 10.1016/j.biopha.2021.111315   
2021 Bozadjieva-Kramer N, Ross RA, Johnson DQ, Fenselau H, Haggerty DL, Atwood B, Lowell B, Flak JN. The Role of Mediobasal Hypothalamic PACAP in the Control of Body Weight and Metabolism. Endocrinology. PMID 33460433 DOI: 10.1210/endocr/bqab012   
2021 Mukai S, Mizokami A, Otani T, Sano T, Matsuda M, Chishaki S, Gao J, Kawakubo-Yasukochi T, Tang R, Kanematsu T, Takeuchi H, Jimi E, Hirata M. Adipocyte-specific GPRC6A ablation promotes diet-induced obesity by inhibiting lipolysis. The Journal of Biological Chemistry. 100274. PMID 33428938 DOI: 10.1016/j.jbc.2021.100274   
2021 Franczyk MP, Qi N, Stromsdorfer KL, Li C, Yamaguchi S, Itoh H, Yoshino M, Sasaki Y, Brookheart RT, Finck BN, DeBosch BJ, Klein S, Yoshino J. Importance of Adipose Tissue NAD+ Biology in Regulating Metabolic Flexibility. Endocrinology. 162. PMID 33543238 DOI: 10.1210/endocr/bqab006   
2021 Kumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, et al. High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance. Nature Communications. 12: 213. PMID 33431899 DOI: 10.1038/s41467-020-20500-w   
2021 Franczyk MP, Qi N, Stromsdorfer KL, Li C, Yamaguchi S, Itoh H, Yoshino M, Sasaki Y, Brookheart RT, Finck BN, DeBosch BJ, Klein S, Yoshino J. Importance of adipose tissue NAD+ biology in regulating metabolic flexibility. Endocrinology. PMID 33433557 DOI: 10.1210/endocr/bqab006   
2021 Zhou H, Peng X, Hu J, Wang L, Luo H, Zhang J, Zhang Y, Li G, Ji Y, Zhang J, Bai J, Liu M, Zhou Z, Liu F. DsbA-L deficiency in T cells promotes diet-induced thermogenesis through suppressing IFN-γ production. Nature Communications. 12: 326. PMID 33436607 DOI: 10.1038/s41467-020-20665-4   
2021 Huang LL, Huang XQ, Zhang XQ, Liu J, Zhang YP, Zhao HY, Huang MQ. [Effect of fucoxanthin on insulin resistance in obese mice induced by high fat diet]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. 46: 171-176. PMID 33645067 DOI: 10.19540/j.cnki.cjcmm.20200927.402   
2021 Zhang LJ, Guerrero-Juarez CF, Chen SX, Zhang X, Yin M, Li F, Wu S, Chen J, Li M, Liu Y, Jiang SIB, Hata T, Plikus MV, Gallo RL. Diet-induced obesity promotes infection by impairment of the innate antimicrobial defense function of dermal adipocyte progenitors. Science Translational Medicine. 13. PMID 33472955 DOI: 10.1126/scitranslmed.abb5280   
2021 Zhai M, Luan P, Shi Y, Li B, Kang J, Hu F, Li M, Du L, Zhou D, Jian W, Peng W. Identification of Three Significant Genes Associated with Immune Cells Infiltration in Dysfunctional Adipose Tissue-Induced Insulin-Resistance of Obese Patients via Comprehensive Bioinformatics Analysis. International Journal of Endocrinology. 2021: 8820089. PMID 33564304 DOI: 10.1155/2021/8820089   
2021 Zhou J, Wang F, Chen J, Yang R, Chen Y, Gu D, Niu T, Luo Q, Yan X, Chen H, Wu W. Long-term kappa-carrageenan consumption leads to moderate metabolic disorder by blocking insulin binding. Pharmacological Research. 105417. PMID 33401003 DOI: 10.1016/j.phrs.2020.105417   
2021 Chen Y, Zhang J, Li P, Liu C, Li L. N1‑methylnicotinamide ameliorates insulin resistance in skeletal muscle of type 2 diabetic mice by activating the SIRT1/PGC‑1α signaling pathway. Molecular Medicine Reports. 23. PMID 33576435 DOI: 10.3892/mmr.2021.11909   
2021 Lee CS, Park MH, Kim BK, Kim SH. Antiobesity Effect of Novel Probiotic Strains in a Mouse Model of High-Fat Diet-Induced Obesity. Probiotics and Antimicrobial Proteins. PMID 33569747 DOI: 10.1007/s12602-021-09752-0   
2021 Ma X, Xiao W, Li H, Pang P, Xue F, Wan L, Pei L, Yan H. Metformin restores hippocampal neurogenesis and learning and memory via regulating gut microbiota in the obese mouse model. Brain, Behavior, and Immunity. PMID 33609653 DOI: 10.1016/j.bbi.2021.02.011   
2021 Juretić N, Sepúlveda R, D'Espessailles A, Vera DB, Cadagan C, de Miguel M, González-Mañán D, Tapia G. Dietary alpha- and gamma-tocopherol (1:5 ratio) supplementation attenuates adipose tissue expansion, hepatic steatosis, and expression of inflammatory markers in a high-fat-diet-fed murine model. Nutrition (Burbank, Los Angeles County, Calif.). 85: 111139. PMID 33549947 DOI: 10.1016/j.nut.2021.111139