| Year |
Citation |
Score |
| 2021 |
Berthier A, Johanns M, Zummo FP, Lefebvre P, Staels B. PPARs in liver physiology. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 1867: 166097. PMID 33524529 DOI: 10.1016/j.bbadis.2021.166097 |
0.312 |
|
| 2018 |
Hering Y, Berthier A, Duez H, Lefebvre P, Deprez B, Gribbon P, Wolf M, Reinshagen J, Halley F, Hannemann J, Böger R, Staels B, Gul S. Development and implementation of a cell-based assay to discover agonists of the nuclear receptor REV-ERBα. Journal of Biological Methods. 5: e94. PMID 31453244 DOI: 10.14440/jbm.2018.244 |
0.302 |
|
| 2018 |
Berthier A, Vinod M, Porez G, Steenackers A, Alexandre J, Yamakawa N, Gheeraert C, Ploton M, Maréchal X, Dubois-Chevalier J, Hovasse A, Schaeffer-Reiss C, Cianférani S, Rolando C, Bray F, ... ... Lefebvre P, et al. Combinatorial regulation of hepatic cytoplasmic signaling and nuclear transcriptional events by the OGT/REV-ERBα complex. Proceedings of the National Academy of Sciences of the United States of America. PMID 30397120 DOI: 10.1073/Pnas.1805397115 |
0.307 |
|
| 2018 |
Ploton M, Mazuy C, Gheeraert C, Dubois V, Berthier A, Dubois-Chevalier J, Maréchal X, Bantubungi-Blum K, Diemer H, Cianférani S, Strub JM, Helleboid-Chapman A, Eeckhoute J, Staels B, Lefebvre P. The Nuclear Bile Acid Receptor FXR is a PKA- and FOXA2-Sensitive Activator of Fasting Hepatic Gluconeogenesis. Journal of Hepatology. PMID 29981427 DOI: 10.1016/J.Jhep.2018.06.022 |
0.385 |
|
| 2017 |
Firmin FF, Oger F, Gheeraert C, Dubois-Chevalier J, Vercoutter-Edouart AS, Alzaid F, Mazuy C, Dehondt H, Alexandre J, Derudas B, Dhalluin Q, Ploton M, Berthier A, Woitrain E, Lefebvre T, ... ... Lefebvre P, et al. The RBM14/CoAA-interacting, long intergenic non-coding RNA Paral1 regulates adipogenesis and coactivates the nuclear receptor PPARγ. Scientific Reports. 7: 14087. PMID 29075020 DOI: 10.1038/S41598-017-14570-Y |
0.381 |
|
| 2017 |
Lefebvre P, Lalloyer F, Baugé E, Pawlak M, Gheeraert C, Dehondt H, Vanhoutte J, Woitrain E, Hennuyer N, Mazuy C, Bobowski-Gérard M, Zummo FP, Derudas B, Driessen A, Hubens G, et al. Interspecies NASH disease activity whole-genome profiling identifies a fibrogenic role of PPARα-regulated dermatopontin. Jci Insight. 2. PMID 28679947 DOI: 10.1172/Jci.Insight.92264 |
0.33 |
|
| 2017 |
Dubois V, Eeckhoute J, Lefebvre P, Staels B. Distinct but complementary contributions of PPAR isotypes to energy homeostasis. The Journal of Clinical Investigation. 127: 1202-1214. PMID 28368286 DOI: 10.1172/Jci88894 |
0.353 |
|
| 2017 |
Chávez-Talavera O, Tailleux A, Lefebvre P, Staels B. Bile acid control of metabolism and inflammation in obesity, type 2 diabetes, dyslipidemia and NAFLD. Gastroenterology. PMID 28214524 DOI: 10.1053/J.Gastro.2017.01.055 |
0.404 |
|
| 2017 |
Le-Guevel R, Oger F, Martinez-Jimenez CP, Bizot M, Gheeraert C, Firmin F, Ploton M, Kretova M, Palierne G, Staels B, Barath P, Talianidis I, Lefebvre P, Eeckhoute J, Salbert G. Inactivation of the nuclear orphan receptor COUP-TFII by small chemicals. Acs Chemical Biology. PMID 28059499 DOI: 10.1021/Acschembio.6B00593 |
0.449 |
|
| 2016 |
Gross B, Pawlak M, Lefebvre P, Staels B. PPARs in obesity-induced T2DM, dyslipidaemia and NAFLD. Nature Reviews. Endocrinology. PMID 27636730 DOI: 10.1038/Nrendo.2016.135 |
0.329 |
|
| 2016 |
Hennuyer N, Duplan I, Paquet C, Vanhoutte J, Woitrain E, Touche V, Colin S, Vallez E, Lestavel S, Lefebvre P, Staels B. The novel selective PPARα modulator (SPPARMα) pemafibrate improves dyslipidemia, enhances reverse cholesterol transport and decreases inflammation and atherosclerosis. Atherosclerosis. PMID 27108950 DOI: 10.1016/J.Atherosclerosis.2016.03.003 |
0.319 |
|
| 2015 |
Trabelsi MS, Daoudi M, Prawitt J, Ducastel S, Touche V, Sayin SI, Perino A, Brighton CA, Sebti Y, Kluza J, Briand O, Dehondt H, Vallez E, Dorchies E, Baud G, ... ... Lefebvre P, et al. Farnesoid X receptor inhibits glucagon-like peptide-1 production by enteroendocrine L cells. Nature Communications. 6: 7629. PMID 26134028 DOI: 10.1038/Ncomms8629 |
0.384 |
|
| 2015 |
De Paoli F, Eeckhoute J, Copin C, Vanhoutte J, Duhem C, Derudas B, Dubois-Chevalier J, Colin S, Zawadzki C, Jude B, Haulon S, Lefebvre P, Staels B, Chinetti-Gbaguidi G. The neuron-derived orphan receptor 1 (NOR1) is induced upon human alternative macrophage polarization and stimulates the expression of markers of the M2 phenotype. Atherosclerosis. 241: 18-26. PMID 25941992 DOI: 10.1016/J.Atherosclerosis.2015.04.798 |
0.304 |
|
| 2015 |
Lefebvre P, Staels B. SREBF2-embedded mir33 links the nuclear bile acid receptor FXR to cholesterol and lipoprotein metabolism. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 748-9. PMID 25810294 DOI: 10.1161/Atvbaha.115.305317 |
0.356 |
|
| 2015 |
Francque S, Verrijken A, Caron S, Prawitt J, Paumelle R, Derudas B, Lefebvre P, Taskinen MR, Van Hul W, Mertens I, Hubens G, Van Marck E, Michielsen P, Van Gaal L, Staels B. PPARα gene expression correlates with severity and histological treatment response in patients with non-alcoholic steatohepatitis. Journal of Hepatology. 63: 164-73. PMID 25703085 DOI: 10.1016/J.Jhep.2015.02.019 |
0.318 |
|
| 2015 |
Dubois-Chevalier J, Staels B, Lefebvre P, Eeckhoute J. The ubiquitous transcription factor CTCF promotes lineage-specific epigenomic remodeling and establishment of transcriptional networks driving cell differentiation. Nucleus (Austin, Tex.). 6: 15-8. PMID 25565413 DOI: 10.1080/19491034.2015.1004258 |
0.398 |
|
| 2015 |
Mazuy C, Helleboid A, Staels B, Lefebvre P. Nuclear bile acid signaling through the farnesoid X receptor. Cellular and Molecular Life Sciences : Cmls. 72: 1631-50. PMID 25511198 DOI: 10.1007/S00018-014-1805-Y |
0.398 |
|
| 2015 |
Pawlak M, Lefebvre P, Staels B. Molecular mechanism of PPARα action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease. Journal of Hepatology. 62: 720-33. PMID 25450203 DOI: 10.1016/J.Jhep.2014.10.039 |
0.395 |
|
| 2014 |
Benhamed F, Filhoulaud G, Caron S, Lefebvre P, Staels B, Postic C. O-GlcNAcylation Links ChREBP and FXR to Glucose-Sensing. Frontiers in Endocrinology. 5: 230. PMID 25628602 DOI: 10.3389/Fendo.2014.00230 |
0.387 |
|
| 2014 |
Dubois-Chevalier J, Oger F, Dehondt H, Firmin FF, Gheeraert C, Staels B, Lefebvre P, Eeckhoute J. A dynamic CTCF chromatin binding landscape promotes DNA hydroxymethylation and transcriptional induction of adipocyte differentiation. Nucleic Acids Research. 42: 10943-59. PMID 25183525 DOI: 10.1093/Nar/Gku780 |
0.416 |
|
| 2014 |
Pawlak M, Baugé E, Bourguet W, De Bosscher K, Lalloyer F, Tailleux A, Lebherz C, Lefebvre P, Staels B. The transrepressive activity of peroxisome proliferator-activated receptor alpha is necessary and sufficient to prevent liver fibrosis in mice. Hepatology (Baltimore, Md.). 60: 1593-606. PMID 24995693 DOI: 10.1002/Hep.27297 |
0.363 |
|
| 2014 |
Lien F, Berthier A, Bouchaert E, Gheeraert C, Alexandre J, Porez G, Prawitt J, Dehondt H, Ploton M, Colin S, Lucas A, Patrice A, Pattou F, Diemer H, Van Dorsselaer A, ... ... Lefebvre P, et al. Metformin interferes with bile acid homeostasis through AMPK-FXR crosstalk. The Journal of Clinical Investigation. 124: 1037-51. PMID 24531544 DOI: 10.1172/Jci68815 |
0.434 |
|
| 2014 |
Oger F, Dubois-Chevalier J, Gheeraert C, Avner S, Durand E, Froguel P, Salbert G, Staels B, Lefebvre P, Eeckhoute J. Peroxisome proliferator-activated receptor γ regulates genes involved in insulin/insulin-like growth factor signaling and lipid metabolism during adipogenesis through functionally distinct enhancer classes. The Journal of Biological Chemistry. 289: 708-22. PMID 24288131 DOI: 10.1074/Jbc.M113.526996 |
0.426 |
|
| 2014 |
Berrabah W, Aumercier P, Gheeraert C, Dehondt H, Bouchaert E, Alexandre J, Ploton M, Mazuy C, Caron S, Tailleux A, Eeckhoute J, Lefebvre T, Staels B, Lefebvre P. Glucose sensing O-GlcNAcylation pathway regulates the nuclear bile acid receptor farnesoid X receptor (FXR). Hepatology (Baltimore, Md.). 59: 2022-33. PMID 24037988 DOI: 10.1002/Hep.26710 |
0.387 |
|
| 2013 |
Flajollet S, Staels B, Lefebvre P. Retinoids and nuclear retinoid receptors in white and brown adipose tissues: physiopathologic aspects. Hormone Molecular Biology and Clinical Investigation. 14: 75-86. PMID 25436722 DOI: 10.1515/Hmbci-2013-0013 |
0.355 |
|
| 2013 |
Mazuy C, Ploton M, Eeckhoute J, Berrabah W, Staels B, Lefebvre P, Helleboid-Chapman A. Palmitate increases Nur77 expression by modulating ZBP89 and Sp1 binding to the Nur77 proximal promoter in pancreatic β-cells. Febs Letters. PMID 24512852 DOI: 10.1016/J.Febslet.2013.10.024 |
0.357 |
|
| 2013 |
Porez G, Gross B, Prawitt J, Gheeraert C, Berrabah W, Alexandre J, Staels B, Lefebvre P. The hepatic orosomucoid/α1-acid glycoprotein gene cluster is regulated by the nuclear bile acid receptor FXR. Endocrinology. 154: 3690-701. PMID 23861371 DOI: 10.1210/En.2013-1263 |
0.44 |
|
| 2013 |
Flajollet S, Rachez C, Ploton M, Schulz C, Gallais R, Métivier R, Pawlak M, Leray A, Issulahi AA, Héliot L, Staels B, Salbert G, Lefebvre P. The elongation complex components BRD4 and MLLT3/AF9 are transcriptional coactivators of nuclear retinoid receptors. Plos One. 8: e64880. PMID 23762261 DOI: 10.1371/Journal.Pone.0064880 |
0.432 |
|
| 2013 |
Caron S, Huaman Samanez C, Dehondt H, Ploton M, Briand O, Lien F, Dorchies E, Dumont J, Postic C, Cariou B, Lefebvre P, Staels B. Farnesoid X receptor inhibits the transcriptional activity of carbohydrate response element binding protein in human hepatocytes. Molecular and Cellular Biology. 33: 2202-11. PMID 23530060 DOI: 10.1128/Mcb.01004-12 |
0.463 |
|
| 2012 |
Eeckhoute J, Oger F, Staels B, Lefebvre P. Coordinated Regulation of PPARγ Expression and Activity through Control of Chromatin Structure in Adipogenesis and Obesity. Ppar Research. 2012: 164140. PMID 22991504 DOI: 10.1155/2012/164140 |
0.427 |
|
| 2012 |
Sérandour AA, Avner S, Oger F, Bizot M, Percevault F, Lucchetti-Miganeh C, Palierne G, Gheeraert C, Barloy-Hubler F, Péron CL, Madigou T, Durand E, Froguel P, Staels B, Lefebvre P, et al. Dynamic hydroxymethylation of deoxyribonucleic acid marks differentiation-associated enhancers. Nucleic Acids Research. 40: 8255-65. PMID 22730288 DOI: 10.1093/Nar/Gks595 |
0.363 |
|
| 2012 |
Berthier A, Oger F, Gheeraert C, Boulahtouf A, Le Guével R, Balaguer P, Staels B, Salbert G, Lefebvre P. The novel antibacterial compound walrycin A induces human PXR transcriptional activity. Toxicological Sciences : An Official Journal of the Society of Toxicology. 127: 225-35. PMID 22314385 DOI: 10.1093/Toxsci/Kfs073 |
0.409 |
|
| 2012 |
Briand O, Helleboid-Chapman A, Ploton M, Hennuyer N, Carpentier R, Pattou F, Vandewalle B, Moerman E, Gmyr V, Kerr-Conte J, Eeckhoute J, Staels B, Lefebvre P. The nuclear orphan receptor Nur77 is a lipotoxicity sensor regulating glucose-induced insulin secretion in pancreatic β-cells. Molecular Endocrinology (Baltimore, Md.). 26: 399-413. PMID 22301783 DOI: 10.1210/Me.2011-1317 |
0.399 |
|
| 2012 |
Pawlak M, Lefebvre P, Staels B. General molecular biology and architecture of nuclear receptors. Current Topics in Medicinal Chemistry. 12: 486-504. PMID 22242852 DOI: 10.2174/156802612799436641 |
0.434 |
|
| 2012 |
Chinetti-Gbaguidi G, Bouhlel MA, Copin C, Duhem C, Derudas B, Neve B, Noel B, Eeckhoute J, Lefebvre P, Seckl JR, Staels B. Peroxisome proliferator-activated receptor-γ activation induces 11β-hydroxysteroid dehydrogenase type 1 activity in human alternative macrophages. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 677-85. PMID 22207732 DOI: 10.1161/Atvbaha.111.241364 |
0.356 |
|
| 2011 |
Berrabah W, Aumercier P, Lefebvre P, Staels B. Control of nuclear receptor activities in metabolism by post-translational modifications. Febs Letters. 585: 1640-50. PMID 21486568 DOI: 10.1016/J.Febslet.2011.03.066 |
0.417 |
|
| 2010 |
Lefebvre P, Benomar Y, Staels B. Retinoid X receptors: common heterodimerization partners with distinct functions. Trends in Endocrinology and Metabolism: Tem. 21: 676-83. PMID 20674387 DOI: 10.1016/J.Tem.2010.06.009 |
0.456 |
|
| 2010 |
Lefebvre B, Benomar Y, Guédin A, Langlois A, Hennuyer N, Dumont J, Bouchaert E, Dacquet C, Pénicaud L, Casteilla L, Pattou F, Ktorza A, Staels B, Lefebvre P. Proteasomal degradation of retinoid X receptor alpha reprograms transcriptional activity of PPARgamma in obese mice and humans. The Journal of Clinical Investigation. 120: 1454-68. PMID 20364085 DOI: 10.1172/Jci38606 |
0.356 |
|
| 2009 |
Lefebvre P, Cariou B, Lien F, Kuipers F, Staels B. Role of bile acids and bile acid receptors in metabolic regulation. Physiological Reviews. 89: 147-91. PMID 19126757 DOI: 10.1152/Physrev.00010.2008 |
0.393 |
|
| 2008 |
Rigamonti E, Fontaine C, Lefebvre B, Duhem C, Lefebvre P, Marx N, Staels B, Chinetti-Gbaguidi G. Induction of CXCR2 receptor by peroxisome proliferator-activated receptor gamma in human macrophages. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 932-9. PMID 18292390 DOI: 10.1161/Atvbaha.107.161679 |
0.399 |
|
| 2008 |
Carpentier R, Sacchetti P, Ségard P, Staels B, Lefebvre P. The glucocorticoid receptor is a co-regulator of the orphan nuclear receptor Nurr1. Journal of Neurochemistry. 104: 777-89. PMID 17986226 DOI: 10.1111/J.1471-4159.2007.05055.X |
0.708 |
|
| 2007 |
Carmona MC, Louche K, Lefebvre B, Pilon A, Hennuyer N, Audinot-Bouchez V, Fievet C, Torpier G, Formstecher P, Renard P, Lefebvre P, Dacquet C, Staels B, Casteilla L, Pénicaud L, et al. S 26948: a new specific peroxisome proliferator activated receptor gamma modulator with potent antidiabetes and antiatherogenic effects. Diabetes. 56: 2797-808. PMID 17704298 DOI: 10.2337/Db06-1734 |
0.375 |
|
| 2007 |
Flajollet S, Lefebvre B, Cudejko C, Staels B, Lefebvre P. The core component of the mammalian SWI/SNF complex SMARCD3/BAF60c is a coactivator for the nuclear retinoic acid receptor. Molecular and Cellular Endocrinology. 270: 23-32. PMID 17363140 DOI: 10.1016/J.Mce.2007.02.004 |
0.417 |
|
| 2006 |
Sacchetti P, Carpentier R, Ségard P, Olivé-Cren C, Lefebvre P. Multiple signaling pathways regulate the transcriptional activity of the orphan nuclear receptor NURR1. Nucleic Acids Research. 34: 5515-27. PMID 17020917 DOI: 10.1093/Nar/Gkl712 |
0.71 |
|
| 2006 |
Flajollet S, Lefebvre B, Rachez C, Lefebvre P. Distinct roles of the steroid receptor coactivator 1 and of MED1 in retinoid-induced transcription and cellular differentiation. The Journal of Biological Chemistry. 281: 20338-48. PMID 16723356 DOI: 10.1074/Jbc.M603023200 |
0.451 |
|
| 2006 |
Lefebvre B, Brand C, Flajollet S, Lefebvre P. Down-regulation of the tumor suppressor gene retinoic acid receptor beta2 through the phosphoinositide 3-kinase/Akt signaling pathway. Molecular Endocrinology (Baltimore, Md.). 20: 2109-21. PMID 16613989 DOI: 10.1210/Me.2005-0321 |
0.392 |
|
| 2006 |
Lefebvre P, Chinetti G, Fruchart JC, Staels B. Sorting out the roles of PPAR alpha in energy metabolism and vascular homeostasis. The Journal of Clinical Investigation. 116: 571-80. PMID 16511589 DOI: 10.1172/Jci27989 |
0.37 |
|
| 2006 |
Dedieu S, Lefebvre P. Retinoids interfere with the AP1 signalling pathway in human breast cancer cells. Cellular Signalling. 18: 889-98. PMID 16176868 DOI: 10.1016/J.Cellsig.2005.08.001 |
0.337 |
|
| 2005 |
Martin PJ, Lardeux V, Lefebvre P. The proliferating cell nuclear antigen regulates retinoic acid receptor transcriptional activity through direct protein-protein interaction. Nucleic Acids Research. 33: 4311-21. PMID 16055921 DOI: 10.1093/Nar/Gki745 |
0.452 |
|
| 2005 |
Geffroy N, Guédin A, Dacquet C, Lefebvre P. Cell cycle regulation of breast cancer cells through estrogen-induced activities of ERK and Akt protein kinases. Molecular and Cellular Endocrinology. 237: 11-23. PMID 15925090 DOI: 10.1016/J.Mce.2005.04.003 |
0.357 |
|
| 2005 |
Rousseaux C, Lefebvre B, Dubuquoy L, Lefebvre P, Romano O, Auwerx J, Metzger D, Wahli W, Desvergne B, Naccari GC, Chavatte P, Farce A, Bulois P, Cortot A, Colombel JF, et al. Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gamma. The Journal of Experimental Medicine. 201: 1205-15. PMID 15824083 DOI: 10.1084/Jem.20041948 |
0.401 |
|
| 2005 |
Lefebvre P, Martin PJ, Flajollet S, Dedieu S, Billaut X, Lefebvre B. Transcriptional activities of retinoic acid receptors. Vitamins and Hormones. 70: 199-264. PMID 15727806 DOI: 10.1016/S0083-6729(05)70007-8 |
0.416 |
|
| 2005 |
Duez H, Lefebvre B, Poulain P, Torra IP, Percevault F, Luc G, Peters JM, Gonzalez FJ, Gineste R, Helleboid S, Dzavik V, Fruchart JC, Fiévet C, Lefebvre P, Staels B. Regulation of human apoA-I by gemfibrozil and fenofibrate through selective peroxisome proliferator-activated receptor alpha modulation. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 585-91. PMID 15618549 DOI: 10.1161/01.Atv.0000154140.73570.00 |
0.374 |
|
| 2003 |
Eeckhoute J, Oxombre B, Formstecher P, Lefebvre P, Laine B. Critical role of charged residues in helix 7 of the ligand binding domain in Hepatocyte Nuclear Factor 4alpha dimerisation and transcriptional activity. Nucleic Acids Research. 31: 6640-50. PMID 14602925 DOI: 10.1093/Nar/Gkg850 |
0.377 |
|
| 2003 |
Martin PJ, Delmotte MH, Formstecher P, Lefebvre P. PLZF is a negative regulator of retinoic acid receptor transcriptional activity. Nuclear Receptor. 1: 6. PMID 14521715 DOI: 10.1186/1478-1336-1-6 |
0.474 |
|
| 2003 |
Jouault T, Ibata-Ombetta S, Takeuchi O, Trinel PA, Sacchetti P, Lefebvre P, Akira S, Poulain D. Candida albicans phospholipomannan is sensed through toll-like receptors. The Journal of Infectious Diseases. 188: 165-72. PMID 12825186 DOI: 10.1086/375784 |
0.662 |
|
| 2002 |
Sacchetti P, Dwornik H, Formstecher P, Rachez C, Lefebvre P. Requirements for heterodimerization between the orphan nuclear receptor Nurr1 and retinoid X receptors. The Journal of Biological Chemistry. 277: 35088-96. PMID 12122012 DOI: 10.1074/Jbc.M205816200 |
0.71 |
|
| 2002 |
Benkoussa M, Brand C, Delmotte MH, Formstecher P, Lefebvre P. Retinoic acid receptors inhibit AP1 activation by regulating extracellular signal-regulated kinase and CBP recruitment to an AP1-responsive promoter. Molecular and Cellular Biology. 22: 4522-34. PMID 12052862 DOI: 10.1128/Mcb.22.13.4522-4534.2002 |
0.417 |
|
| 2002 |
Brand C, Ségard P, Plouvier P, Formstecher P, Danzé PM, Lefebvre P. Selective alteration of gene expression in response to natural and synthetic retinoids. Bmc Pharmacology. 2: 13. PMID 12019025 DOI: 10.1186/1471-2210-2-13 |
0.418 |
|
| 2002 |
Lefebvre B, Brand C, Lefebvre P, Ozato K. Chromosomal integration of retinoic acid response elements prevents cooperative transcriptional activation by retinoic acid receptor and retinoid X receptor. Molecular and Cellular Biology. 22: 1446-59. PMID 11839811 DOI: 10.1128/Mcb.22.5.1446-1459.2002 |
0.404 |
|
| 2001 |
Biola A, Lefebvre P, Perrin-Wolff M, Sturm M, Bertoglio J, Pallardy M. Interleukin-2 inhibits glucocorticoid receptor transcriptional activity through a mechanism involving STAT5 (signal transducer and activator of transcription 5) but not AP-1. Molecular Endocrinology (Baltimore, Md.). 15: 1062-76. PMID 11435608 DOI: 10.1210/Mend.15.7.0657 |
0.4 |
|
| 2001 |
Depoix C, Delmotte MH, Formstecher P, Lefebvre P. Control of retinoic acid receptor heterodimerization by ligand-induced structural transitions. A novel mechanism of action for retinoid antagonists. The Journal of Biological Chemistry. 276: 9452-9. PMID 11254657 DOI: 10.1074/Jbc.M008004200 |
0.412 |
|
| 2000 |
Prima V, Depoix C, Masselot B, Formstecher P, Lefebvre P. Alteration of the glucocorticoid receptor subcellular localization by non steroidal compounds. The Journal of Steroid Biochemistry and Molecular Biology. 72: 1-12. PMID 10731632 DOI: 10.1016/S0960-0760(99)00146-6 |
0.443 |
|
| 1999 |
Delmotte MH, Tahayato A, Formstecher P, Lefebvre P. Serine 157, a retinoic acid receptor alpha residue phosphorylated by protein kinase C in vitro, is involved in RXR.RARalpha heterodimerization and transcriptional activity. The Journal of Biological Chemistry. 274: 38225-31. PMID 10608897 DOI: 10.1074/Jbc.274.53.38225 |
0.429 |
|
| 1999 |
Martinon F, Michelet C, Peguillet I, Taoufik Y, Lefebvre P, Goujard C, Guillet J, Delfraissy J, Lantz O. Persistent alterations in T-cell repertoire, cytokine and chemokine receptor gene expression after 1 year of highly active antiretroviral therapy. Aids. 13: 185-194. PMID 10202824 DOI: 10.1097/00002030-199902040-00006 |
0.303 |
|
| 1999 |
Mouchon A, Delmotte MH, Formstecher P, Lefebvre P. Allosteric regulation of the discriminative responsiveness of retinoic acid receptor to natural and synthetic ligands by retinoid X receptor and DNA. Molecular and Cellular Biology. 19: 3073-85. PMID 10082574 DOI: 10.1128/Mcb.19.4.3073 |
0.458 |
|
| 1998 |
Lefebvre B, Mouchon A, Formstecher P, Lefebvre P. Distinct modes of interaction of the retinoic acid receptor alpha with natural and synthetic retinoids. Molecular and Cellular Endocrinology. 139: 161-9. PMID 9705084 DOI: 10.1016/S0303-7207(98)00065-3 |
0.397 |
|
| 1998 |
Tahayato A, Rachez C, Formstecher P, Lefebvre P. Analysis of Retinoid Receptor Phosphorylation Methods of Molecular Biology. 89: 277-291. PMID 9664335 DOI: 10.1385/0-89603-438-0:277 |
0.348 |
|
| 1998 |
Lefebvre B, Mouchon A, Formstecher P, Lefebvre P. H11-H12 loop retinoic acid receptor mutants exhibit distinct trans-activating and trans-repressing activities in the presence of natural or synthetic retinoids. Biochemistry. 37: 9240-9. PMID 9649304 DOI: 10.1021/Bi9804840 |
0.385 |
|
| 1998 |
Lefebvre P, Mouchon A, Lefebvre B, Formstecher P. Binding of retinoic acid receptor heterodimers to DNA. A role for histones NH2 termini. The Journal of Biological Chemistry. 273: 12288-95. PMID 9575180 DOI: 10.1074/Jbc.273.20.12288 |
0.426 |
|
| 1997 |
Dao-Phan HP, Formstecher P, Lefebvre P. Disruption of the glucocorticoid receptor assembly with heat shock protein 90 by a peptidic antiglucocorticoid. Molecular Endocrinology (Baltimore, Md.). 11: 962-72. PMID 9178755 DOI: 10.1210/Mend.11.7.9937 |
0.399 |
|
| 1996 |
Rachez C, Sautière P, Formstecher P, Lefebvre P. Identification of Amino Acids Critical for the DNA Binding and Dimerization Properties of the Human Retinoic Acid Receptor α IMPORTANCE OF LYSINE 360, LYSINE 365, AND VALINE 361 Journal of Biological Chemistry. 271: 17996-18006. PMID 8663386 DOI: 10.1074/Jbc.271.30.17996 |
0.396 |
|
| 1995 |
Lefebvre P, Gaub M, Tahayato A, Rochette-Egly C, Formstecher P. Protein Phosphatases 1 and 2A Regulate the Transcriptional and DNA Binding Activities of Retinoic Acid Receptors Journal of Biological Chemistry. 270: 10806-10816. PMID 7738017 DOI: 10.1074/Jbc.270.18.10806 |
0.443 |
|
| 1995 |
Lefebvre B, Rachez C, Formstecher P, Lefebvre P. Structural determinants of the ligand-binding site of the human retinoic acid receptor alpha. Biochemistry. 34: 5477-5485. PMID 7727406 DOI: 10.1021/Bi00016A019 |
0.347 |
|
| 1993 |
Tahayato A, Lefebvre P, Formstecher P, Dautrevaux M. A protein kinase C-dependent activity modulates retinoic acid-induced transcription Molecular Endocrinology. 7: 1642-1653. PMID 8145770 DOI: 10.1210/Mend.7.12.8145770 |
0.386 |
|
| 1992 |
Archer TK, Lefebvre P, Wolford RG, Hager GL. Transcription factor loading on the MMTV promoter: a bimodal mechanism for promoter activation. Science (New York, N.Y.). 255: 1573-6. PMID 1347958 DOI: 10.1126/Science.1347958 |
0.397 |
|
| 1991 |
Lefebvre P, Berard DS, Cordingley MG, Hager GL. Two regions of the mouse mammary tumor virus long terminal repeat regulate the activity of its promoter in mammary cell lines. Molecular and Cellular Biology. 11: 2529-37. PMID 1708094 DOI: 10.1128/Mcb.11.5.2529 |
0.349 |
|
| 1990 |
Bresnick EH, John S, Berard DS, LeFebvre P, Hager GL. Glucocorticoid receptor-dependent disruption of a specific nucleosome on the mouse mammary tumor virus promoter is prevented by sodium butyrate. Proceedings of the National Academy of Sciences of the United States of America. 87: 3977-81. PMID 2160080 DOI: 10.1073/Pnas.87.10.3977 |
0.413 |
|
| 1989 |
Lefebvre P, Sablonniere B, Tbarka N, Formstecher P, Dautrevaux M. Study of the heteromeric structure of the untransformed glucocorticoid receptor using chemical cross-linking and monoclonal antibodies against the 90K heat-shock protein Biochemical and Biophysical Research Communications. 159: 677-686. PMID 2930536 DOI: 10.1016/0006-291X(89)90048-X |
0.305 |
|
| 1989 |
Lefebvre P, Formstecher P, Rousseau GG, Lustenberger P, Dautrevaux M. Improvement in glucocorticoid receptor binding affinity concomitant to shift from antagonist to agonist activity in a series of 17 beta-carboxamide derivatives of dexamethasone. Journal of Steroid Biochemistry. 33: 557-563. PMID 2811365 DOI: 10.1016/0022-4731(89)90041-1 |
0.332 |
|
| 1988 |
Lefebvre P, Formstecher P, Richard C, Dautrevaux M. RU 486 stabilizes a high molecular weight form of the glucocorticoid receptor containing the 90K non-steroid binding protein in intact thymus cells Biochemical and Biophysical Research Communications. 150: 1221-1229. PMID 3342067 DOI: 10.1016/0006-291X(88)90759-0 |
0.357 |
|
| 1988 |
Lefebvre P, Danze PM, Sablonniere B, Richard C, Formstecher P, Dautrevaux M. Association of the glucocorticoid receptor binding subunit with the 90K nonsteroid-binding component is stabilized by both steroidal and nonsteroidal antiglucocorticoids in intact cells Biochemistry. 27: 9186-9194. PMID 3242623 DOI: 10.1021/Bi00426A017 |
0.405 |
|
| 1988 |
Formstecher P, Lefebvre P, Dautrevaux M. RU 486 stabilizes the glucocorticoid receptor in a non-transformed high molecular weight form in intact thymus cells under physiological conditions. Journal of Steroid Biochemistry. 31: 607-612. PMID 3199809 DOI: 10.1016/0022-4731(88)90012-X |
0.306 |
|
| 1988 |
Sablonniere B, Economidis IV, Lefebvre P, Place M, Richard C, Formstecher P, Rousseau GG, Dautrevaux M. RNA binding to the untransformed glucocorticoid receptor. Sensitivity to substrate-specific ribonucleases and characterization of a ribonucleic acid associated with the purified receptor. Febs Journal. 177: 371-382. PMID 2461303 DOI: 10.1111/J.1432-1033.1988.Tb14386.X |
0.36 |
|
| 1987 |
Sablonniere B, Lefebvre P, Formstecher P, Dautrevaux M. Improved Stokes radius measurement of the glucocorticoid receptor using TSK G4000SW and TSK G3000SW high-performance size-exclusion columns. Analytical and preparative applications. Journal of Chromatography A. 403: 183-196. PMID 3680408 DOI: 10.1016/S0021-9673(00)96352-0 |
0.337 |
|
| 1986 |
Sablonniere B, Danze PM, Formstecher P, Lefebvre P, Dautrevaux M. Physical characterization of the activated and non-activated forms of the glucocorticoid-receptor complex bound to the steroid antagonist [3H]RU 486. Journal of Steroid Biochemistry. 25: 605-614. PMID 3795940 DOI: 10.1016/0022-4731(86)90001-4 |
0.369 |
|
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