Guido Reifenberger, M.D. - Publications

Affiliations: 
Department of Neuropathology Heinrich Heine University Düsseldorf, Düsseldorf, Nordrhein-Westfalen, Germany 

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Year Citation  Score
2020 Herrera-Rios D, Mughal SS, Teuber-Hanselmann S, Pierscianek D, Sucker A, Jansen P, Schimming T, Klode J, Reifenberger J, Felsberg J, Keyvani K, Brors B, Sure U, Reifenberger G, Schadendorf D, et al. Macrophages/Microglia Represent the Major Source of Indolamine 2,3-Dioxygenase Expression in Melanoma Metastases of the Brain. Frontiers in Immunology. 11: 120. PMID 32117271 DOI: 10.3389/fimmu.2020.00120  0.4
2019 Reinhardt A, Stichel D, Schrimpf D, Koelsche C, Wefers AK, Ebrahimi A, Sievers P, Huang K, Casalini MB, Fernández-Klett F, Suwala A, Weller M, Gramatzki D, Felsberg J, Reifenberger G, et al. Tumors diagnosed as cerebellar glioblastoma comprise distinct molecular entities. Acta Neuropathologica Communications. 7: 163. PMID 31661039 DOI: 10.1186/s40478-019-0801-8  0.6
2018 Reinhardt A, Stichel D, Schrimpf D, Sahm F, Korshunov A, Reuss DE, Koelsche C, Huang K, Wefers AK, Hovestadt V, Sill M, Gramatzki D, Felsberg J, Reifenberger G, Koch A, et al. Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations. Acta Neuropathologica. PMID 29564591 DOI: 10.1007/s00401-018-1837-8  0.6
2018 Capper D, Jones DTW, Sill M, Hovestadt V, Schrimpf D, Sturm D, Koelsche C, Sahm F, Chavez L, Reuss DE, Kratz A, Wefers AK, Huang K, Pajtler KW, Schweizer L, ... ... Reifenberger G, et al. DNA methylation-based classification of central nervous system tumours. Nature. PMID 29539639 DOI: 10.1038/nature26000  0.6
2016 Louis DN, Perry A, Reifenberger G, von Deimling A, Figarella-Branger D, Cavenee WK, Ohgaki H, Wiestler OD, Kleihues P, Ellison DW. The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary. Acta Neuropathologica. 131: 803-20. PMID 27157931 DOI: 10.1007/s00401-016-1545-1  0.8
2015 Herrlinger U, Jones DT, Glas M, Hattingen E, Gramatzki D, Stuplich M, Felsberg J, Bähr O, Gielen GH, Simon M, Wiewrodt D, Schabet M, Hovestadt V, Capper D, Steinbach JP, ... ... Reifenberger G, et al. Gliomatosis cerebri: no evidence for a separate brain tumor entity. Acta Neuropathologica. PMID 26493382 DOI: 10.1007/s00401-015-1495-z  0.8
2015 Korshunov A, Capper D, Reuss D, Schrimpf D, Ryzhova M, Hovestadt V, Sturm D, Meyer J, Jones C, Zheludkova O, Kumirova E, Golanov A, Kool M, Schüller U, Mittelbronn M, ... ... Reifenberger G, et al. Histologically distinct neuroepithelial tumors with histone 3 G34 mutation are molecularly similar and comprise a single nosologic entity. Acta Neuropathologica. PMID 26482474 DOI: 10.1007/s00401-015-1493-1  0.8
2015 Reuss DE, Kratz A, Sahm F, Capper D, Schrimpf D, Koelsche C, Hovestadt V, Bewerunge-Hudler M, Jones DT, Schittenhelm J, Mittelbronn M, Rushing E, Simon M, Westphal M, Unterberg A, ... ... Reifenberger G, et al. Adult IDH wild type astrocytomas biologically and clinically resolve into other tumor entities. Acta Neuropathologica. PMID 26087904 DOI: 10.1007/s00401-015-1454-8  0.8
2015 Weller M, Weber RG, Willscher E, Riehmer V, Hentschel B, Kreuz M, Felsberg J, Beyer U, Löffler-Wirth H, Kaulich K, Steinbach JP, Hartmann C, Gramatzki D, Schramm J, Westphal M, ... ... Reifenberger G, et al. Molecular classification of diffuse cerebral WHO grade II/III gliomas using genome- and transcriptome-wide profiling improves stratification of prognostically distinct patient groups. Acta Neuropathologica. 129: 679-93. PMID 25783747 DOI: 10.1007/s00401-015-1409-0  0.8
2015 Korshunov A, Ryzhova M, Hovestadt V, Bender S, Sturm D, Capper D, Meyer J, Schrimpf D, Kool M, Northcott PA, Zheludkova O, Milde T, Witt O, Kulozik AE, Reifenberger G, et al. Integrated analysis of pediatric glioblastoma reveals a subset of biologically favorable tumors with associated molecular prognostic markers. Acta Neuropathologica. 129: 669-78. PMID 25752754 DOI: 10.1007/s00401-015-1405-4  0.8
2015 Weller M, Tabatabai G, Kästner B, Felsberg J, Steinbach JP, Wick A, Schnell O, Hau P, Herrlinger U, Sabel MC, Wirsching HG, Ketter R, Bähr O, Platten M, Tonn JC, ... ... Reifenberger G, et al. MGMT Promoter Methylation Is a Strong Prognostic Biomarker for Benefit from Dose-Intensified Temozolomide Rechallenge in Progressive Glioblastoma: The DIRECTOR Trial. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 2057-64. PMID 25655102 DOI: 10.1158/1078-0432.CCR-14-2737  0.8
2015 Dunkl V, Cleff C, Stoffels G, Judov N, Sarikaya-Seiwert S, Law I, Bøgeskov L, Nysom K, Andersen SB, Steiger HJ, Fink GR, Reifenberger G, Shah NJ, Coenen HH, Langen KJ, et al. The usefulness of dynamic O-(2-18F-fluoroethyl)-L-tyrosine PET in the clinical evaluation of brain tumors in children and adolescents. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 56: 88-92. PMID 25525183 DOI: 10.2967/jnumed.114.148734  0.8
2015 Galldiks N, Dunkl V, Stoffels G, Hutterer M, Rapp M, Sabel M, Reifenberger G, Kebir S, Dorn F, Blau T, Herrlinger U, Hau P, Ruge MI, Kocher M, Goldbrunner R, et al. Diagnosis of pseudoprogression in patients with glioblastoma using O-(2-[18F]fluoroethyl)-L-tyrosine PET. European Journal of Nuclear Medicine and Molecular Imaging. 42: 685-95. PMID 25411133 DOI: 10.1007/s00259-014-2959-4  0.8
2015 Röck K, Tigges J, Sass S, Schütze A, Florea AM, Fender AC, Theis FJ, Krutmann J, Boege F, Fritsche E, Reifenberger G, Fischer JW. miR-23a-3p causes cellular senescence by targeting hyaluronan synthase 2: possible implication for skin aging. The Journal of Investigative Dermatology. 135: 369-77. PMID 25264594 DOI: 10.1038/jid.2014.422  0.8
2014 Waldera-Lupa DM, Kalfalah F, Florea AM, Sass S, Kruse F, Rieder V, Tigges J, Fritsche E, Krutmann J, Busch H, Boerries M, Meyer HE, Boege F, Theis F, Reifenberger G, et al. Proteome-wide analysis reveals an age-associated cellular phenotype of in situ aged human fibroblasts. Aging. 6: 856-78. PMID 25411231  0.8
2014 Codo P, Weller M, Meister G, Szabo E, Steinle A, Wolter M, Reifenberger G, Roth P. MicroRNA-mediated down-regulation of NKG2D ligands contributes to glioma immune escape. Oncotarget. 5: 7651-62. PMID 25277195  0.8
2014 Northcott PA, Lee C, Zichner T, Stütz AM, Erkek S, Kawauchi D, Shih DJ, Hovestadt V, Zapatka M, Sturm D, Jones DT, Kool M, Remke M, Cavalli FM, Zuyderduyn S, ... ... Reifenberger G, et al. Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma. Nature. 511: 428-34. PMID 25043047 DOI: 10.1038/nature13379  0.8
2014 Wiestler B, Capper D, Hovestadt V, Sill M, Jones DT, Hartmann C, Felsberg J, Platten M, Feiden W, Keyvani K, Pfister SM, Wiestler OD, Meyermann R, Reifenberger G, Pietsch T, et al. Assessing CpG island methylator phenotype, 1p/19q codeletion, and MGMT promoter methylation from epigenome-wide data in the biomarker cohort of the NOA-04 trial. Neuro-Oncology. 16: 1630-8. PMID 25028501 DOI: 10.1093/neuonc/nou138  0.8
2014 Wiestler B, Capper D, Sill M, Jones DT, Hovestadt V, Sturm D, Koelsche C, Bertoni A, Schweizer L, Korshunov A, Weiß EK, Schliesser MG, Radbruch A, Herold-Mende C, Roth P, ... ... Reifenberger G, et al. Integrated DNA methylation and copy-number profiling identify three clinically and biologically relevant groups of anaplastic glioma. Acta Neuropathologica. 128: 561-71. PMID 25008768 DOI: 10.1007/s00401-014-1315-x  0.8
2014 Louis DN, Perry A, Burger P, Ellison DW, Reifenberger G, von Deimling A, Aldape K, Brat D, Collins VP, Eberhart C, Figarella-Branger D, Fuller GN, Giangaspero F, Giannini C, Hawkins C, et al. International Society Of Neuropathology--Haarlem consensus guidelines for nervous system tumor classification and grading. Brain Pathology (Zurich, Switzerland). 24: 429-35. PMID 24990071 DOI: 10.1111/bpa.12171  0.8
2014 Wick W, Weller M, van den Bent M, Sanson M, Weiler M, von Deimling A, Plass C, Hegi M, Platten M, Reifenberger G. MGMT testing--the challenges for biomarker-based glioma treatment. Nature Reviews. Neurology. 10: 372-85. PMID 24912512 DOI: 10.1038/nrneurol.2014.100  0.8
2014 Hovestadt V, Jones DT, Picelli S, Wang W, Kool M, Northcott PA, Sultan M, Stachurski K, Ryzhova M, Warnatz HJ, Ralser M, Brun S, Bunt J, Jäger N, Kleinheinz K, ... ... Reifenberger G, et al. Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing. Nature. 510: 537-41. PMID 24847876 DOI: 10.1038/nature13268  0.8
2014 Pietsch T, Schmidt R, Remke M, Korshunov A, Hovestadt V, Jones DT, Felsberg J, Kaulich K, Goschzik T, Kool M, Northcott PA, von Hoff K, von Bueren AO, Friedrich C, Mynarek M, ... ... Reifenberger G, et al. Prognostic significance of clinical, histopathological, and molecular characteristics of medulloblastomas in the prospective HIT2000 multicenter clinical trial cohort. Acta Neuropathologica. 128: 137-49. PMID 24791927 DOI: 10.1007/s00401-014-1276-0  0.8
2014 Riehmer V, Gietzelt J, Beyer U, Hentschel B, Westphal M, Schackert G, Sabel MC, Radlwimmer B, Pietsch T, Reifenberger G, Weller M, Weber RG, Loeffler M. Genomic profiling reveals distinctive molecular relapse patterns in IDH1/2 wild-type glioblastoma. Genes, Chromosomes & Cancer. 53: 589-605. PMID 24706357 DOI: 10.1002/gcc.22169  0.8
2014 Kool M, Jones DT, Jäger N, Northcott PA, Pugh TJ, Hovestadt V, Piro RM, Esparza LA, Markant SL, Remke M, Milde T, Bourdeaut F, Ryzhova M, Sturm D, Pfaff E, ... ... Reifenberger G, et al. Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition. Cancer Cell. 25: 393-405. PMID 24651015 DOI: 10.1016/j.ccr.2014.02.004  0.8
2014 Reifenberger G, Weber RG, Riehmer V, Kaulich K, Willscher E, Wirth H, Gietzelt J, Hentschel B, Westphal M, Simon M, Schackert G, Schramm J, Matschke J, Sabel MC, Gramatzki D, et al. Molecular characterization of long-term survivors of glioblastoma using genome- and transcriptome-wide profiling. International Journal of Cancer. Journal International Du Cancer. 135: 1822-31. PMID 24615357 DOI: 10.1002/ijc.28836  0.8
2014 Weller M, Kaulich K, Hentschel B, Felsberg J, Gramatzki D, Pietsch T, Simon M, Westphal M, Schackert G, Tonn JC, von Deimling A, Davis T, Weiss WA, Loeffler M, Reifenberger G, et al. Assessment and prognostic significance of the epidermal growth factor receptor vIII mutation in glioblastoma patients treated with concurrent and adjuvant temozolomide radiochemotherapy. International Journal of Cancer. Journal International Du Cancer. 134: 2437-47. PMID 24614983 DOI: 10.1002/ijc.28576  0.8
2013 Galldiks N, Stoffels G, Ruge MI, Rapp M, Sabel M, Reifenberger G, Erdem Z, Shah NJ, Fink GR, Coenen HH, Langen KJ. Role of O-(2-18F-fluoroethyl)-L-tyrosine PET as a diagnostic tool for detection of malignant progression in patients with low-grade glioma. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 54: 2046-54. PMID 24159047 DOI: 10.2967/jnumed.113.123836  0.8
2013 Wick W, Meisner C, Hentschel B, Platten M, Schilling A, Wiestler B, Sabel MC, Koeppen S, Ketter R, Weiler M, Tabatabai G, von Deimling A, Gramatzki D, Westphal M, Schackert G, ... ... Reifenberger G, et al. Prognostic or predictive value of MGMT promoter methylation in gliomas depends on IDH1 mutation. Neurology. 81: 1515-22. PMID 24068788 DOI: 10.1212/WNL.0b013e3182a95680  0.8
2013 Hartmann C, Hentschel B, Simon M, Westphal M, Schackert G, Tonn JC, Loeffler M, Reifenberger G, Pietsch T, von Deimling A, Weller M. Long-term survival in primary glioblastoma with versus without isocitrate dehydrogenase mutations. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 5146-57. PMID 23918605 DOI: 10.1158/1078-0432.CCR-13-0017  0.8
2013 Jones DT, Hutter B, Jäger N, Korshunov A, Kool M, Warnatz HJ, Zichner T, Lambert SR, Ryzhova M, Quang DA, Fontebasso AM, Stütz AM, Hutter S, Zuckermann M, Sturm D, ... ... Reifenberger G, et al. Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. Nature Genetics. 45: 927-32. PMID 23817572 DOI: 10.1038/ng.2682  0.8
2013 Tönjes M, Barbus S, Park YJ, Wang W, Schlotter M, Lindroth AM, Pleier SV, Bai AH, Karra D, Piro RM, Felsberg J, Addington A, Lemke D, Weibrecht I, Hovestadt V, ... ... Reifenberger G, et al. BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1. Nature Medicine. 19: 901-8. PMID 23793099 DOI: 10.1038/nm.3217  0.8
2013 Hovestadt V, Remke M, Kool M, Pietsch T, Northcott PA, Fischer R, Cavalli FM, Ramaswamy V, Zapatka M, Reifenberger G, Rutkowski S, Schick M, Bewerunge-Hudler M, Korshunov A, Lichter P, et al. Robust molecular subgrouping and copy-number profiling of medulloblastoma from small amounts of archival tumour material using high-density DNA methylation arrays. Acta Neuropathologica. 125: 913-6. PMID 23670100 DOI: 10.1007/s00401-013-1126-5  0.8
2013 Wiestler B, Claus R, Hartlieb SA, Schliesser MG, Weiss EK, Hielscher T, Platten M, Dittmann LM, Meisner C, Felsberg J, Happold C, Simon M, Nikkhah G, Papsdorf K, Steinbach JP, ... ... Reifenberger G, et al. Malignant astrocytomas of elderly patients lack favorable molecular markers: an analysis of the NOA-08 study collective. Neuro-Oncology. 15: 1017-26. PMID 23595628 DOI: 10.1093/neuonc/not043  0.8
2012 Sturm D, Witt H, Hovestadt V, Khuong-Quang DA, Jones DT, Konermann C, Pfaff E, Tönjes M, Sill M, Bender S, Kool M, Zapatka M, Becker N, Zucknick M, Hielscher T, ... ... Reifenberger G, et al. Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma. Cancer Cell. 22: 425-37. PMID 23079654 DOI: 10.1016/j.ccr.2012.08.024  0.8
2012 Liu XY, Gerges N, Korshunov A, Sabha N, Khuong-Quang DA, Fontebasso AM, Fleming A, Hadjadj D, Schwartzentruber J, Majewski J, Dong Z, Siegel P, Albrecht S, Croul S, Jones DT, ... ... Reifenberger G, et al. Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations. Acta Neuropathologica. 124: 615-25. PMID 22886134 DOI: 10.1007/s00401-012-1031-3  0.8
2012 Jones DT, Jäger N, Kool M, Zichner T, Hutter B, Sultan M, Cho YJ, Pugh TJ, Hovestadt V, Stütz AM, Rausch T, Warnatz HJ, Ryzhova M, Bender S, Sturm D, ... ... Reifenberger G, et al. Dissecting the genomic complexity underlying medulloblastoma. Nature. 488: 100-5. PMID 22832583 DOI: 10.1038/nature11284  0.8
2012 von dem Knesebeck A, Felsberg J, Waha A, Hartmann W, Scheffler B, Glas M, Hammes J, Mikeska T, Yan PS, Endl E, Simon M, Reifenberger G, Pietsch T, Waha A. RANK (TNFRSF11A) is epigenetically inactivated and induces apoptosis in gliomas. Neoplasia (New York, N.Y.). 14: 526-34. PMID 22787434 DOI: 10.1596/neo.12360  0.8
2012 Sasaki M, Knobbe CB, Munger JC, Lind EF, Brenner D, Brüstle A, Harris IS, Holmes R, Wakeham A, Haight J, You-Ten A, Li WY, Schalm S, Su SM, Virtanen C, ... Reifenberger G, et al. IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics. Nature. 488: 656-9. PMID 22763442 DOI: 10.1038/nature11323  0.8
2012 Wick W, Platten M, Meisner C, Felsberg J, Tabatabai G, Simon M, Nikkhah G, Papsdorf K, Steinbach JP, Sabel M, Combs SE, Vesper J, Braun C, Meixensberger J, Ketter R, ... ... Reifenberger G, et al. Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial. The Lancet. Oncology. 13: 707-15. PMID 22578793 DOI: 10.1016/S1470-2045(12)70164-X  0.8
2012 Haag D, Zipper P, Westrich V, Karra D, Pfleger K, Toedt G, Blond F, Delhomme N, Hahn M, Reifenberger J, Reifenberger G, Lichter P. Nos2 inactivation promotes the development of medulloblastoma in Ptch1(+/-) mice by deregulation of Gap43-dependent granule cell precursor migration. Plos Genetics. 8: e1002572. PMID 22438824 DOI: 10.1371/journal.pgen.1002572  0.4
2012 Schwartzentruber J, Korshunov A, Liu XY, Jones DT, Pfaff E, Jacob K, Sturm D, Fontebasso AM, Quang DA, Tönjes M, Hovestadt V, Albrecht S, Kool M, Nantel A, Konermann C, ... ... Reifenberger G, et al. Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma. Nature. 482: 226-31. PMID 22286061 DOI: 10.1038/nature10833  0.8
2012 Augustin I, Goidts V, Bongers A, Kerr G, Vollert G, Radlwimmer B, Hartmann C, Herold-Mende C, Reifenberger G, von Deimling A, Boutros M. The Wnt secretion protein Evi/Gpr177 promotes glioma tumourigenesis. Embo Molecular Medicine. 4: 38-51. PMID 22147553 DOI: 10.1002/emmm.201100186  0.8
2012 Reifenberger G, Hentschel B, Felsberg J, Schackert G, Simon M, Schnell O, Westphal M, Wick W, Pietsch T, Loeffler M, Weller M. Predictive impact of MGMT promoter methylation in glioblastoma of the elderly. International Journal of Cancer. Journal International Du Cancer. 131: 1342-50. PMID 22139906 DOI: 10.1002/ijc.27385  0.8
2011 Lindemann C, Hackmann O, Delic S, Schmidt N, Reifenberger G, Riemenschneider MJ. SOCS3 promoter methylation is mutually exclusive to EGFR amplification in gliomas and promotes glioma cell invasion through STAT3 and FAK activation Acta Neuropathologica. 122: 241-251. PMID 21590492 DOI: 10.1007/s00401-011-0832-0  0.8
2011 Hartmann C, Hentschel B, Tatagiba M, Schramm J, Schnell O, Seidel C, Stein R, Reifenberger G, Pietsch T, von Deimling A, Loeffler M, Weller M. Molecular markers in low-grade gliomas: predictive or prognostic? Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 4588-99. PMID 21558404 DOI: 10.1158/1078-0432.CCR-10-3194  0.8
2011 Felsberg J, Thon N, Eigenbrod S, Hentschel B, Sabel MC, Westphal M, Schackert G, Kreth FW, Pietsch T, Löffler M, Weller M, Reifenberger G, Tonn JC. Promoter methylation and expression of MGMT and the DNA mismatch repair genes MLH1, MSH2, MSH6 and PMS2 in paired primary and recurrent glioblastomas. International Journal of Cancer. Journal International Du Cancer. 129: 659-70. PMID 21425258 DOI: 10.1002/ijc.26083  0.8
2011 Kim Y, Reifenberger G, Lu D, Endo T, Carson DA, Gast SM, Meschenmoser K, Nowak M, Schmidt-Wolf IG. Influencing the Wnt signaling pathway in multiple myeloma. Anticancer Research. 31: 725-30. PMID 21378363  0.8
2011 Barbus S, Tews B, Karra D, Hahn M, Radlwimmer B, Delhomme N, Hartmann C, Felsberg J, Krex D, Schackert G, Martinez R, Reifenberger G, Lichter P. Differential retinoic acid signaling in tumors of long- and short-term glioblastoma survivors. Journal of the National Cancer Institute. 103: 598-606. PMID 21346226 DOI: 10.1093/jnci/djr036  0.8
2011 Schindler G, Capper D, Meyer J, Janzarik W, Omran H, Herold-Mende C, Schmieder K, Wesseling P, Mawrin C, Hasselblatt M, Louis DN, Korshunov A, Pfister S, Hartmann C, Paulus W, ... Reifenberger G, et al. Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma. Acta Neuropathologica. 121: 397-405. PMID 21274720 DOI: 10.1007/s00401-011-0802-6  0.8
2011 Toedt G, Barbus S, Wolter M, Felsberg J, Tews B, Blond F, Sabel MC, Hofmann S, Becker N, Hartmann C, Ohgaki H, von Deimling A, Wiestler OD, Hahn M, Lichter P, ... Reifenberger G, et al. Molecular signatures classify astrocytic gliomas by IDH1 mutation status. International Journal of Cancer. Journal International Du Cancer. 128: 1095-103. PMID 20473936 DOI: 10.1002/ijc.25448  0.8
2010 Hartmann C, Hentschel B, Wick W, Capper D, Felsberg J, Simon M, Westphal M, Schackert G, Meyermann R, Pietsch T, Reifenberger G, Weller M, Loeffler M, von Deimling A. Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas. Acta Neuropathologica. 120: 707-18. PMID 21088844 DOI: 10.1007/s00401-010-0781-z  0.8
2010 Reifenberger G, Wesseling P. Molecular diagnostics of brain tumors. Acta Neuropathologica. 120: 549-51. PMID 20927631 DOI: 10.1007/s00401-010-0752-4  0.8
2010 Traenka C, Remke M, Korshunov A, Bender S, Hielscher T, Northcott PA, Witt H, Ryzhova M, Felsberg J, Benner A, Riester S, Scheurlen W, Grunewald TG, von Deimling A, Kulozik AE, ... Reifenberger G, et al. Role of LIM and SH3 protein 1 (LASP1) in the metastatic dissemination of medulloblastoma. Cancer Research. 70: 8003-14. PMID 20924110 DOI: 10.1158/0008-5472.CAN-10-0592  0.8
2010 Riemenschneider MJ, Jeuken JW, Wesseling P, Reifenberger G. Molecular diagnostics of gliomas: state of the art. Acta Neuropathologica. 120: 567-84. PMID 20714900 DOI: 10.1007/s00401-010-0736-4  0.8
2010 Seidel S, Garvalov BK, Wirta V, von Stechow L, Schänzer A, Meletis K, Wolter M, Sommerlad D, Henze AT, Nistér M, Reifenberger G, Lundeberg J, Frisén J, Acker T. A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2 alpha. Brain : a Journal of Neurology. 133: 983-95. PMID 20375133 DOI: 10.1093/brain/awq042  0.8
2010 Liu HK, Wang Y, Belz T, Bock D, Takacs A, Radlwimmer B, Barbus S, Reifenberger G, Lichter P, Schütz G. The nuclear receptor tailless induces long-term neural stem cell expansion and brain tumor initiation. Genes & Development. 24: 683-95. PMID 20360385 DOI: 10.1101/gad.560310  0.8
2010 Waha A, Felsberg J, Hartmann W, von dem Knesebeck A, Mikeska T, Joos S, Wolter M, Koch A, Yan PS, Endl E, Wiestler OD, Reifenberger G, Pietsch T, Waha A. Epigenetic downregulation of mitogen-activated protein kinase phosphatase MKP-2 relieves its growth suppressive activity in glioma cells. Cancer Research. 70: 1689-99. PMID 20124482 DOI: 10.1158/0008-5472.CAN-09-3218  0.8
2010 Küsters-Vandevelde HV, Klaasen A, Küsters B, Groenen PJ, van Engen-van Grunsven IA, van Dijk MR, Reifenberger G, Wesseling P, Blokx WA. Activating mutations of the GNAQ gene: a frequent event in primary melanocytic neoplasms of the central nervous system. Acta Neuropathologica. 119: 317-23. PMID 19936769 DOI: 10.1007/s00401-009-0611-3  0.8
2009 Wick W, Hartmann C, Engel C, Stoffels M, Felsberg J, Stockhammer F, Sabel MC, Koeppen S, Ketter R, Meyermann R, Rapp M, Meisner C, Kortmann RD, Pietsch T, Wiestler OD, ... ... Reifenberger G, et al. NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 5874-80. PMID 19901110 DOI: 10.1200/JCO.2009.23.6497  0.8
2006 Schneider DT, Zahn S, Sievers S, Alemazkour K, Reifenberger G, Wiestler OD, Calaminus G, Göbel U, Perlman EJ. Molecular genetic analysis of central nervous system germ cell tumors with comparative genomic hybridization. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 19: 864-73. PMID 16607373 DOI: 10.1038/modpathol.3800607  0.8
1996 Reifenberger J, Ring GU, Gies U, Cobbers L, Oberstrass J, An HX, Niederacher D, Wechsler W, Reifenberger G. Analysis of p53 mutation and epidermal growth factor receptor amplification in recurrent gliomas with malignant progression. Journal of Neuropathology and Experimental Neurology. 55: 822-31. PMID 8965097  0.8
1996 Reifenberger G, Boström J, Bettag M, Bock WJ, Wechsler W, Kepes JJ. Primary glioblastoma multiforme of the oculomotor nerve. Case report. Journal of Neurosurgery. 84: 1062-6. PMID 8847574 DOI: 10.3171/jns.1996.84.6.1062  0.8
1996 Oberstrass J, Reifenberger G, Reifenberger J, Wechsler W, Collins VP. Mutation of the Von Hippel-Lindau tumour suppressor gene in capillary haemangioblastomas of the central nervous system. The Journal of Pathology. 179: 151-6. PMID 8758206 DOI: 10.1002/(SICI)1096-9896(199606)179:2<151::AID-PATH556>3.0.CO;2-0  0.8
1996 Reifenberger J, Reifenberger G, Ichimura K, Schmidt EE, Wechsler W, Collins VP. Epidermal growth factor receptor expression in oligodendroglial tumors. The American Journal of Pathology. 149: 29-35. PMID 8686753  0.8
1995 Schober R, Bilzer T, Waha A, Reifenberger G, Wechsler W, von Deimling A, Wiestler OD, Westphal M, Kemshead JT, Vega F. The epidermal growth factor receptor in glioblastoma: genomic amplification, protein expression, and patient survival data in a therapeutic trial. Clinical Neuropathology. 14: 169-74. PMID 7671460  0.8
1995 Reifenberger G, Reifenberger J, Bilzer T, Wechsler W, Collins VP. Coexpression of transforming growth factor-alpha and épidermal growth factor receptor in capillary hemangioblastomas of the central nervous system. The American Journal of Pathology. 147: 245-50. PMID 7639324  0.8
1994 Westphal M, Hamel W, Zirkel D, Herrmann HD, Bilzer T, Reifenberger G, Schober R, Wechsler W, Albert FK, Behnke J. Epidermal growth factor receptor expression in human malignant glioma: in vitro and in vivo effects of application of monoclonal antibodies to the epidermal growth factor receptor. Recent Results in Cancer Research. Fortschritte Der Krebsforschung. ProgrèS Dans Les Recherches Sur Le Cancer. 135: 171-84. PMID 8047692  0.8
1994 Reifenberger J, Reifenberger G, Liu L, James CD, Wechsler W, Collins VP. Molecular genetic analysis of oligodendroglial tumors shows preferential allelic deletions on 19q and 1p. The American Journal of Pathology. 145: 1175-90. PMID 7977648  0.8
1992 Figge C, Reifenberger G, Vogeley KT, Messing M, Roosen N, Wechsler W. Immunohistochemical demonstration of proliferating cell nuclear antigen in glioblastomas: pronounced heterogeneity and lack of prognostic significance. Journal of Cancer Research and Clinical Oncology. 118: 289-95. PMID 1374410 DOI: 10.1007/BF01208618  0.8
1992 Reifenberger G, Sieth P, Niederhaus M, Wechsler W. Expression of CD15 in tumours of the nervous system. The Histochemical Journal. 24: 890-901. PMID 1362199 DOI: 10.1007/BF01046360  0.8
1991 Vogeley KT, Bilzer T, Reifenberger G, Wechsler W. Immunochemistry of ethylnitrosourea-induced rat neurinomas, the RN6 neurinoma cell line and their transplantation tumors. Acta Neuropathologica. 82: 78-85. PMID 1719740 DOI: 10.1007/BF00310927  0.8
1990 Tajika Y, Reifenberger G, Kiwit JC, Wechsler W. Metastatic adenocarcinoma in cerebral astrocytoma: clinicopathological and immunohistochemical study with review of the literature. Acta Neurochirurgica. 105: 50-5. PMID 2239381 DOI: 10.1007/BF01664858  0.8
1990 Prior R, Reifenberger G, Wechsler W. Transferrin receptor expression in tumours of the human nervous system: relation to tumour type, grading and tumour growth fraction. Virchows Archiv. a, Pathological Anatomy and Histopathology. 416: 491-6. PMID 2110696 DOI: 10.1007/BF01600299  0.8
1990 Cardesa A, Ribalta T, Vogeley KT, Reifenberger G, Wechsler W, Turusov VS. Pathology of tumours in laboratory animals. Tumours of the rat. Tumours of the peripheral nervous system. Iarc Scientific Publications. 699-724. PMID 2093667  0.8
1990 Sugita Y, Kepes JJ, Shigemori M, Kuramoto S, Reifenberger G, Kiwit JC, Wechsler W. Pleomorphic xanthoastrocytoma with desmoplastic reaction: angiomatous variant. Report of two cases. Clinical Neuropathology. 9: 271-8. PMID 1962743  0.8
1989 Reifenberger G, Deckert M, Wechsler W. Immunohistochemical determination of protein kinase C expression and proliferative activity in human brain tumors. Acta Neuropathologica. 78: 166-75. PMID 2750486 DOI: 10.1007/BF00688205  0.8
1989 Deckert M, Reifenberger G, Wechsler W. Determination of the proliferative potential of human brain tumors using the monoclonal antibody Ki-67. Journal of Cancer Research and Clinical Oncology. 115: 179-88. PMID 2715168 DOI: 10.1007/BF00397921  0.8
1989 Bilzer T, Reifenberger G, Wechsler W. Chemical induction of brain tumors in rats by nitrosoureas: molecular biology and neuropathology. Neurotoxicology and Teratology. 11: 551-6. PMID 2696875 DOI: 10.1016/0892-0362(89)90036-6  0.8
1989 Reifenberger G, Prior R, Deckert M, Wechsler W. Epidermal growth factor receptor expression and growth fraction in human tumours of the nervous system. Virchows Archiv. a, Pathological Anatomy and Histopathology. 414: 147-55. PMID 2563600 DOI: 10.1007/BF00718594  0.8
1989 Prior R, Reifenberger G, Wechsler W. Nerve growth factor receptor in tumours of the human nervous system. Immunohistochemical analysis of receptor expression and tumour growth fraction. Pathology, Research and Practice. 185: 332-8. PMID 2478988 DOI: 10.1016/S0344-0338(89)80008-1  0.8
1989 Reifenberger G, Bilzer T, Seitz RJ, Wechsler W. Expression of vimentin and glial fibrillary acidic protein in ethylnitrosourea-induced rat gliomas and glioma cell lines. Acta Neuropathologica. 78: 270-82. PMID 2475009 DOI: 10.1007/BF00687757  0.8
1987 Szymas J, Reifenberger G, Wechsler W. Leu-M1 immunoreactivity in the human brain. Discrimination between different tumors and between neoplastic and brain tissue. Die Naturwissenschaften. 74: 188-90. PMID 3600813 DOI: 10.1007/BF00372924  0.8
1987 Reifenberger G, Szymas J, Wechsler W. Differential expression of glial- and neuronal-associated antigens in human tumors of the central and peripheral nervous system. Acta Neuropathologica. 74: 105-23. PMID 3314309 DOI: 10.1007/BF00692841  0.8
1987 Reifenberger G, Mai JK, Krajewski S, Wechsler W. Distribution of anti-Leu-7, anti-Leu-11a and anti-Leu-M1 immunoreactivity in the brain of the adult rat. Cell and Tissue Research. 248: 305-13. PMID 2438044 DOI: 10.1007/BF00218197  0.8
Low-probability matches
2020 Weller M, van den Bent M, Preusser M, Le Rhun E, Tonn JC, Minniti G, Bendszus M, Balana C, Chinot O, Dirven L, French P, Hegi ME, Jakola AS, Platten M, Roth P, ... ... Reifenberger G, et al. EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood. Nature Reviews. Clinical Oncology. PMID 33293629 DOI: 10.1038/s41571-020-00447-z  0.2
2020 Sievers P, Hielscher T, Schrimpf D, Stichel D, Reuss DE, Berghoff AS, Neidert MC, Wirsching HG, Mawrin C, Ketter R, Paulus W, Reifenberger G, Lamszus K, Westphal M, Etminan N, et al. CDKN2A/B homozygous deletion is associated with early recurrence in meningiomas. Acta Neuropathologica. PMID 32642869 DOI: 10.1007/s00401-020-02188-w  0.2
2019 Brand F, Förster A, Christians A, Bucher M, Thomé CM, Raab MS, Westphal M, Pietsch T, von Deimling A, Reifenberger G, Claus P, Hentschel B, Weller M, Weber RG. FOCAD loss impacts microtubule assembly, G2/M progression and patient survival in astrocytic gliomas. Acta Neuropathologica. PMID 31473790 DOI: 10.1007/s00401-019-02067-z  0.2
2018 Stichel D, Ebrahimi A, Reuss D, Schrimpf D, Ono T, Shirahata M, Reifenberger G, Weller M, Hänggi D, Wick W, Herold-Mende C, Westphal M, Brandner S, Pfister SM, Capper D, et al. Distribution of EGFR amplification, combined chromosome 7 gain and chromosome 10 loss, and TERT promoter mutation in brain tumors and their potential for the reclassification of IDHwt astrocytoma to glioblastoma. Acta Neuropathologica. PMID 30187121 DOI: 10.1007/s00401-018-1905-0  0.2
2017 Felsberg J, Hentschel B, Kaulich K, Gramatzki D, Zacher A, Malzkorn B, Kamp MA, Sabel MC, Simon M, Westphal M, Schackert G, Tonn JC, Pietsch T, von Deimling A, Loeffler M, ... Reifenberger G, et al. Prognostic role of Epidermal growth factor receptor variant III (EGFRvIII) positivity in EGFR-amplified primary and recurrent glioblastomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28855349 DOI: 10.1158/1078-0432.CCR-17-0890  0.2
2016 Schliesser MG, Claus R, Hielscher T, Grimm C, Weichenhan D, Blaes J, Wiestler B, Hau P, Schramm J, Sahm F, Weiß EK, Weiler M, Baer C, Schmidt-Graf F, Schackert G, ... ... Reifenberger G, et al. Prognostic relevance of miRNA-155 methylation in anaplastic glioma. Oncotarget. PMID 27880937 DOI: 10.18632/oncotarget.13452  0.2
2016 Sturm D, Orr BA, Toprak UH, Hovestadt V, Jones DT, Capper D, Sill M, Buchhalter I, Northcott PA, Leis I, Ryzhova M, Koelsche C, Pfaff E, Allen SJ, Balasubramanian G, ... ... Reifenberger G, et al. New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs. Cell. 164: 1060-1072. PMID 26919435 DOI: 10.1016/j.cell.2016.01.015  0.2
2019 Seystahl K, Hentschel B, Loew S, Gramatzki D, Felsberg J, Herrlinger U, Westphal M, Schackert G, Thon N, Tatagiba M, Pietsch T, Reifenberger G, Löffler M, Wick W, Weller M, et al. Bevacizumab versus alkylating chemotherapy in recurrent glioblastoma. Journal of Cancer Research and Clinical Oncology. PMID 31754832 DOI: 10.1007/s00432-019-03086-9  0.16
2017 Beyer U, Brand F, Martens H, Weder J, Christians A, Elyan N, Hentschel B, Westphal M, Schackert G, Pietsch T, Hong B, Krauss JK, Samii A, Raab P, Das A, ... ... Reifenberger G, et al. Rare ADAR and RNASEH2B variants and a type I interferon signature in glioma and prostate carcinoma risk and tumorigenesis. Acta Neuropathologica. PMID 29030706 DOI: 10.1007/s00401-017-1774-y  0.16
2017 Weller M, van den Bent M, Tonn JC, Stupp R, Preusser M, Cohen-Jonathan-Moyal E, Henriksson R, Rhun EL, Balana C, Chinot O, Bendszus M, Reijneveld JC, Dhermain F, French P, Marosi C, ... ... Reifenberger G, et al. Evidence-based management of adult patients with diffuse glioma - Authors' reply. The Lancet. Oncology. 18: e430-e431. PMID 28759377 DOI: 10.1016/S1470-2045(17)30515-6  0.16
2017 Weller M, van den Bent M, Tonn JC, Stupp R, Preusser M, Cohen-Jonathan-Moyal E, Henriksson R, Rhun EL, Balana C, Chinot O, Bendszus M, Reijneveld JC, Dhermain F, French P, Marosi C, ... ... Reifenberger G, et al. European Association for Neuro-Oncology (EANO) guideline on the diagnosis and treatment of adult astrocytic and oligodendroglial gliomas. The Lancet. Oncology. PMID 28483413 DOI: 10.1016/S1470-2045(17)30194-8  0.16
2017 Gramatzki D, Kickingereder P, Hentschel B, Felsberg J, Herrlinger U, Schackert G, Tonn JC, Westphal M, Sabel M, Schlegel U, Wick W, Pietsch T, Reifenberger G, Loeffler M, Bendszus M, et al. Limited role for extended maintenance temozolomide for newly diagnosed glioblastoma. Neurology. PMID 28298550 DOI: 10.1212/WNL.0000000000003809  0.16
2016 Gramatzki D, Roth P, Felsberg J, Hofer S, Rushing EJ, Hentschel B, Westphal M, Krex D, Simon M, Schnell O, Wick W, Reifenberger G, Weller M. Chemotherapy for intracranial ependymoma in adults. Bmc Cancer. 16: 287. PMID 27108407 DOI: 10.1186/s12885-016-2323-0  0.16
2015 Wolpert F, Happold C, Reifenberger G, Florea AM, Deenen R, Roth P, Neidert MC, Lamszus K, Westphal M, Weller M, Eisele G. Interferon-β Modulates the Innate Immune Response against Glioblastoma Initiating Cells. Plos One. 10: e0139603. PMID 26441059 DOI: 10.1371/journal.pone.0139603  0.16
2010 Temme A, Geiger KD, Wiedemuth R, Conseur K, Pietsch T, Felsberg J, Reifenberger G, Tatsuka M, Hagel C, Westphal M, Berger H, Simon M, Weller M, Schackert G. Giant cell glioblastoma is associated with altered aurora b expression and concomitant p53 mutation. Journal of Neuropathology and Experimental Neurology. 69: 632-42. PMID 20467329 DOI: 10.1097/NEN.0b013e3181e4c06e  0.16
2016 Malzkorn B, Reifenberger G. Practical implications of integrated glioma classification according to the World Health Organization classification of tumors of the central nervous system 2016. Current Opinion in Oncology. PMID 27606698 DOI: 10.1097/CCO.0000000000000327  0.12
2019 Petersen JK, Boldt HB, Sorensen M, Dahlrot RH, Hansen S, Burton M, Thomassen M, Kruse T, Poulsen FR, Andreasen L, Hager H, Ulhøi BP, Lukacova S, Reifenberger G, Kristensen B. GENE-33. INTEGRATED GLIOMA DIAGNOSTICS USING TARGETED NEXT-GENERATION SEQUENCING Neuro-Oncology. 21: vi104-vi104. DOI: 10.1093/neuonc/noz175.435  0.08
2020 Sievers P, Sill M, Blume C, Tauziede-Espariat A, Schrimpf D, Stichel D, Reuss DE, Dogan H, Hartmann C, Mawrin C, Hasselblatt M, Stummer W, Schick U, Hench J, Frank S, ... ... Reifenberger G, et al. Clear cell meningiomas are defined by a highly distinct DNA methylation profile and mutations in SMARCE1. Acta Neuropathologica. PMID 33319313 DOI: 10.1007/s00401-020-02247-2  0.04
2020 Breitkopf K, Aytulun A, Förster M, Kraus B, Turowski B, Huppert D, Goebels N, Hefter H, Aktas O, Metz I, Brück W, Reifenberger G, Hartung HP, Albrecht P. Case Report: A Case of Severe Clinical Deterioration in a Patient With Multiple Sclerosis. Frontiers in Neurology. 11: 782. PMID 32973648 DOI: 10.3389/fneur.2020.00782  0.04
2019 Wirthschaft P, Bode J, Soni H, Dietrich F, Krüwel T, Fischer B, Knobbe-Thomsen CB, Rossetti G, Hentschel A, Mack N, Schönig K, Breckwoldt MO, Schmandke A, Pusch S, Medenbach J, ... ... Reifenberger G, et al. RhoA regulates translation of the Nogo-A decoy SPARC in white matter-invading glioblastomas. Acta Neuropathologica. PMID 31062076 DOI: 10.1007/s00401-019-02021-z  0.04
2019 Körber V, Yang J, Barah P, Wu Y, Stichel D, Gu Z, Fletcher MNC, Jones D, Hentschel B, Lamszus K, Tonn JC, Schackert G, Sabel M, Felsberg J, Zacher A, ... ... Reifenberger G, et al. Evolutionary Trajectories of IDH Glioblastomas Reveal a Common Path of Early Tumorigenesis Instigated Years ahead of Initial Diagnosis. Cancer Cell. PMID 30905762 DOI: 10.1016/j.ccell.2019.02.007  0.04
2019 Hou Y, Pinheiro J, Sahm F, Reuss DE, Schrimpf D, Stichel D, Casalini B, Koelsche C, Sievers P, Wefers AK, Reinhardt A, Ebrahimi A, Fernández-Klett F, Pusch S, Meier J, ... ... Reifenberger G, et al. Papillary glioneuronal tumor (PGNT) exhibits a characteristic methylation profile and fusions involving PRKCA. Acta Neuropathologica. PMID 30759284 DOI: 10.1007/s00401-019-01969-2  0.04
2018 Sievers P, Stichel D, Hielscher T, Schrimpf D, Reinhardt A, Wefers AK, Reuss D, Jones DTW, Bewerunge-Hudler M, Hartmann C, Baumgarten P, Wirsching HG, Winther-Kristensen B, Brokinkel B, Ketter R, ... ... Reifenberger G, et al. Chordoid meningiomas can be sub-stratified into prognostically distinct DNA methylation classes and are enriched for heterozygous deletions of chromosomal arm 2p. Acta Neuropathologica. PMID 30382370 DOI: 10.1007/s00401-018-1924-x  0.04
2018 Sievers P, Stichel D, Schrimpf D, Sahm F, Koelsche C, Reuss DE, Wefers AK, Reinhardt A, Huang K, Ebrahimi A, Hou Y, Pajtler KW, Pfister SM, Hasselblatt M, Stummer W, ... ... Reifenberger G, et al. FGFR1:TACC1 fusion is a frequent event in molecularly defined extraventricular neurocytoma. Acta Neuropathologica. PMID 29978331 DOI: 10.1007/s00401-018-1882-3  0.04
2018 Wirthschaft P, Bode J, Simon AEM, Hoffmann E, van Laack R, Krüwel T, Dietrich F, Bucher D, Hahn A, Sahm F, Breckwoldt MO, Kurz FT, Hielscher T, Fischer B, Dross N, ... ... Reifenberger G, et al. A PRDX1-p38α heterodimer amplifies MET-driven invasion of IDH-wildtype and IDH-mutant gliomas. International Journal of Cancer. PMID 29582423 DOI: 10.1002/ijc.31404  0.04
2016 Wick W, Roth P, Hartmann C, Hau P, Nakamura M, Stockhammer F, Sabel MC, Wick A, Koeppen S, Ketter R, Vajkoczy P, Eyupoglu I, Kalff R, Happold C, Galldiks N, ... ... Reifenberger G, et al. Long-term analysis of the NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with PCV or temozolomide. Neuro-Oncology. PMID 27370396 DOI: 10.1093/neuonc/now133  0.04
2015 Wolter M, Werner T, Malzkorn B, Reifenberger G. Role of microRNAs Located on Chromosome Arm 10q in Malignant Gliomas. Brain Pathology (Zurich, Switzerland). PMID 26223576 DOI: 10.1111/bpa.12294  0.01
2012 Husseini L, Saleh A, Reifenberger G, Hartung HP, Kieseier BC. Inflammatory demyelinating brain lesions heralding primary CNS lymphoma. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 39: 6-10. PMID 22384490 DOI: 10.1017/S0317167100012610  0.04
2011 Malzkorn B, Wolter M, Riemenschneider MJ, Reifenberger G. Unraveling the glioma epigenome: from molecular mechanisms to novel biomarkers and therapeutic targets. Brain Pathology (Zurich, Switzerland). 21: 619-32. PMID 21939466 DOI: 10.1111/j.1750-3639.2011.00536.x  0.04
2020 Wu Y, Fletcher M, Gu Z, Wang Q, Costa B, Bertoni A, Man KH, Schlotter M, Felsberg J, Mangei J, Barbus M, Gaupel AC, Wang W, Weiss T, Eils R, ... ... Reifenberger G, et al. Glioblastoma epigenome profiling identifies SOX10 as a master regulator of molecular tumour subtype. Nature Communications. 11: 6434. PMID 33339831 DOI: 10.1038/s41467-020-20225-w  0.01
2020 Unger K, Fleischmann DF, Ruf V, Felsberg J, Piehlmaier D, Samaga D, Hess J, Suresh MP, Mittelbronn M, Lauber K, Budach W, Sabel M, Rödel C, Reifenberger G, Herms J, et al. Improved risk stratification in younger wild-type glioblastoma patients by combining a 4-miRNA signature with promoter methylation status. Neuro-Oncology Advances. 2: vdaa137. PMID 33305269 DOI: 10.1093/noajnl/vdaa137  0.01
2020 Sørensen MD, Nielsen O, Reifenberger G, Kristensen BW. The presence of TIM-3 positive cells in WHO grade III and IV astrocytic gliomas correlates with isocitrate dehydrogenase mutation status. Brain Pathology (Zurich, Switzerland). e12921. PMID 33244787 DOI: 10.1111/bpa.12921  0.01
2020 Alasad K, Voeltzke K, Levin L, Reifenberger G, Leprivier G, Rotblat B. 4EBP1/2 are active under standard cell culture conditions to regulate the translation of specific mRNAs. Cell Death & Disease. 11: 968. PMID 33177490 DOI: 10.1038/s41419-020-03182-6  0.01
2020 Weller M, Reifenberger G. Beyond the World Health Organization classification of central nervous system tumors 2016: what are the new developments for gliomas from a clinician's perspective? Current Opinion in Neurology. 33: 701-706. PMID 33177376 DOI: 10.1097/WCO.0000000000000871  0.01
2020 Gramatzki D, Felsberg J, Roth P, Kaulich K, von Deimling A, Rushing EJ, Reifenberger G, Weller M. The molecular evolution of glioblastoma treated by gross total resection alone. Neuro-Oncology. PMID 33173940 DOI: 10.1093/neuonc/noaa261  0.01
2020 Sievers P, Sill M, Schrimpf D, Stichel D, Reuss DE, Sturm D, Hench J, Frank S, Krskova L, Vicha A, Zapotocky M, Bison B, Castel D, Grill J, Debily MA, ... ... Reifenberger G, et al. A subset of pediatric-type thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of EGFR. Neuro-Oncology. PMID 33130881 DOI: 10.1093/neuonc/noaa251  0.01
2020 Tzaridis T, Schäfer N, Weller J, Steinbach JP, Schlegel U, Seidel S, Sabel M, Hau P, Seidel C, Krex D, Goldbrunner R, Tonn JC, Grauer O, Kebir S, Schneider M, ... ... Reifenberger G, et al. MGMT promoter methylation analysis for allocating combined CCNU/TMZ chemotherapy: lessons learned from the CeTeG/NOA-09 trial. International Journal of Cancer. PMID 33113214 DOI: 10.1002/ijc.33363  0.01
2020 Berger K, Turowski B, Felsberg J, Malzkorn B, Reifenberger G, Steiger HJ, Budach W, Haussmann J, Knipps J, Rapp M, Hänggi D, Sabel M, Mijderwijk HJ, Kamp MA. Age-stratified clinical performance and survival of patients with IDH-wildtype glioblastoma homogeneously treated by radiotherapy with concomitant and maintenance temozolomide. Journal of Cancer Research and Clinical Oncology. PMID 32748120 DOI: 10.1007/s00432-020-03334-3  0.01
2020 Petersen JK, Boldt HB, Sørensen MD, Blach S, Dahlrot RH, Hansen S, Burton M, Thomassen M, Kruse T, Poulsen FR, Andreasen L, Hager H, Ulhøi BP, Lukacova S, Reifenberger G, et al. Targeted next-generation sequencing of adult gliomas for retrospective prognostic evaluation and up-front diagnostics. Neuropathology and Applied Neurobiology. PMID 32696543 DOI: 10.1111/nan.12645  0.01
2020 Lohmann B, Silginer M, Picard D, Schneider H, Remke M, Roth P, Reifenberger G, Weller M. Interferon-β exposure induces a fragile glioblastoma stem cell phenotype with a transcriptional profile of reduced migratory and MAPK pathway activity. Neuro-Oncology Advances. 2: vdaa043. PMID 32642697 DOI: 10.1093/noajnl/vdaa043  0.01
2020 Riemenschneider MJ, Fischer J, Grassow-Narlik M, Mawrin C, von Deimling A, Pietsch T, Reifenberger G, Mueller WC, Sommer CJ, Dietel M, Zoubaa S, Lorenz J, Rothhammer-Hampl T. Quality assurance in neuropathology: Experiences from the round robin trials on mutation and promoter methylation testing launched by the Quality Assurance Initiative Pathology (QuIP) in 2018 and 2019. Clinical Neuropathology. PMID 32352373 DOI: 10.5414/NP301278  0.01
2020 Louis DN, Wesseling P, Aldape K, Brat DJ, Capper D, Cree IA, Eberhart C, Figarella-Branger D, Fouladi M, Fuller GN, Giannini C, Haberler C, Hawkins C, Komori T, Kros JM, ... ... Reifenberger G, et al. cIMPACT-NOW update 6: new entity and diagnostic principle recommendations of the cIMPACT-Utrecht meeting on future CNS tumor classification and grading. Brain Pathology (Zurich, Switzerland). PMID 32307792 DOI: 10.1111/bpa.12832  0.01
2020 Wick A, Kessler T, Platten M, Meisner C, Bamberg M, Herrlinger U, Felsberg J, Weyerbrock A, Papsdorf K, Steinbach JP, Sabel M, Vesper J, Debus J, Meixensberger J, Ketter R, ... ... Reifenberger G, et al. Superiority of temozolomide over radiotherapy for elderly patients with RTK II methylation class, MGMT promoter-methylated malignant astrocytoma. Neuro-Oncology. PMID 32064499 DOI: 10.1093/neuonc/noaa033  0.01
2020 Bauer EK, Stoffels G, Blau T, Reifenberger G, Felsberg J, Werner JM, Lohmann P, Rosen J, Ceccon G, Tscherpel C, Rapp M, Sabel M, Filss CP, Shah NJ, Neumaier B, et al. Prediction of survival in patients with IDH-wildtype astrocytic gliomas using dynamic O-(2-[F]-fluoroethyl)-L-tyrosine PET. European Journal of Nuclear Medicine and Molecular Imaging. PMID 32034446 DOI: 10.1007/s00259-020-04695-0  0.01
2020 Brat DJ, Aldape K, Colman H, Figrarella-Branger D, Fuller GN, Giannini C, Holland EC, Jenkins RB, Kleinschmidt-DeMasters B, Komori T, Kros JM, Louis DN, McLean C, Perry A, Reifenberger G, et al. cIMPACT-NOW update 5: recommended grading criteria and terminologies for IDH-mutant astrocytomas. Acta Neuropathologica. PMID 31996992 DOI: 10.1007/s00401-020-02127-9  0.01
2019 Barthel FP, Johnson KC, Varn FS, Moskalik AD, Tanner G, Kocakavuk E, Anderson KJ, Abiola O, Aldape K, Alfaro KD, Alpar D, Amin SB, Ashley DM, Bandopadhayay P, Barnholtz-Sloan JS, ... ... Reifenberger G, et al. Longitudinal molecular trajectories of diffuse glioma in adults. Nature. PMID 31748746 DOI: 10.1038/s41586-019-1775-1  0.01
2019 Thomas C, Wefers A, Bens S, Nemes K, Agaimy A, Oyen F, Vogelgesang S, Rodriguez FJ, Brett FM, McLendon R, Bodi I, Burel-Vandenbos F, Keyvani K, Tippelt S, Poulsen FR, ... ... Reifenberger G, et al. Desmoplastic myxoid tumor, SMARCB1-mutant: clinical, histopathological and molecular characterization of a pineal region tumor encountered in adolescents and adults. Acta Neuropathologica. PMID 31732806 DOI: 10.1007/s00401-019-02094-w  0.01
2019 Sievers P, Schrimpf D, Stichel D, Reuss DE, Hasselblatt M, Hagel C, Staszewski O, Hench J, Frank S, Brandner S, Korshunov A, Wick W, Pfister SM, Reifenberger G, von Deimling A, et al. Posterior fossa pilocytic astrocytomas with oligodendroglial features show frequent FGFR1 activation via fusion or mutation. Acta Neuropathologica. PMID 31729570 DOI: 10.1007/s00401-019-02097-7  0.01
2019 An Z, Knobbe-Thomsen CB, Wan X, Fan QW, Reifenberger G, Weiss WA. Correction: EGFR Cooperates with EGFRvIII to Recruit Macrophages in Glioblastoma. Cancer Research. 79: 5681. PMID 31676678 DOI: 10.1158/0008-5472.CAN-19-2800  0.01
2019 Von Achenbach C, Weller M, Kaulich K, Gramatzki D, Zacher A, Fabbro D, Reifenberger G, Szabó E. Synergistic growth inhibition mediated by dual PI3K/mTOR pathway targeting and genetic or direct pharmacological AKT inhibition in human glioblastoma models. Journal of Neurochemistry. PMID 31618458 DOI: 10.1111/jnc.14899  0.01
2019 Le Rhun E, Preusser M, Roth P, Reardon DA, van den Bent M, Wen P, Reifenberger G, Weller M. Molecular targeted therapy of glioblastoma. Cancer Treatment Reviews. 80: 101896. PMID 31541850 DOI: 10.1016/j.ctrv.2019.101896  0.01
2019 Louis DN, Wesseling P, Brandner S, Brat DJ, Ellison DW, Giangaspero F, Hattab EM, Hawkins C, Judge MJ, Kleinschmidt-DeMasters B, Komori T, McLean C, Paulus W, Perry A, Reifenberger G, et al. Data Sets for the Reporting of Tumors of the Central Nervous System. Archives of Pathology & Laboratory Medicine. PMID 31219344 DOI: 10.5858/arpa.2018-0565-OA  0.01
2019 Varon M, Levy T, Mazor G, Ben David H, Marciano R, Kerlin Y, Prasad M, Elkabets M, Pauck D, Ahmadov U, Picard D, Qin N, Borkhardt A, Reifenberger G, Leprivier G, et al. The long non-coding RNA TP73-AS1 promotes tumorigenicity of medulloblastoma cells. International Journal of Cancer. PMID 31081944 DOI: 10.1002/ijc.32400  0.01
2019 Louis DN, Ellison DW, Brat DJ, Aldape K, Capper D, Hawkins C, Paulus W, Perry A, Reifenberger G, Figarella-Branger D, von Deimling A, Wesseling P. cIMPACT-NOW: A practical summary of diagnostic points from Round 1 updates. Brain Pathology (Zurich, Switzerland). PMID 31038238 DOI: 10.1111/bpa.12732  0.01
2019 Mazor G, Levin L, Picard D, Ahmadov U, Carén H, Borkhardt A, Reifenberger G, Leprivier G, Remke M, Rotblat B. The lncRNA TP73-AS1 is linked to aggressiveness in glioblastoma and promotes temozolomide resistance in glioblastoma cancer stem cells. Cell Death & Disease. 10: 246. PMID 30867410 DOI: 10.1038/s41419-019-1477-5  0.01
2019 Ellison DW, Hawkins C, Jones DTW, Onar-Thomas A, Pfister SM, Reifenberger G, Louis DN. cIMPACT-NOW update 4: diffuse gliomas characterized by MYB, MYBL1, or FGFR1 alterations or BRAF mutation. Acta Neuropathologica. PMID 30848347 DOI: 10.1007/s00401-019-01987-0  0.01
2019 Rezniczek GA, Grunwald C, Hilal Z, Scheich J, Reifenberger G, Tannapfel A, Tempfer CB. ROBO1 Expression in Metastasizing Breast and Ovarian Cancer: SLIT2-induced Chemotaxis Requires Heparan Sulfates (Heparin). Anticancer Research. 39: 1267-1273. PMID 30842157 DOI: 10.21873/anticanres.13237  0.01
2019 Krais AM, Park YJ, Reifenberger G, Meister M, Plass C, Schmeiser HH. Sensitive detection of hydroxymethylcytosine levels in normal and neoplastic cells and tissues. Electrophoresis. PMID 30724377 DOI: 10.1002/elps.201800523  0.01
2019 Gobin M, Nazarov PV, Warta R, Timmer M, Reifenberger G, Felsberg J, Vallar L, Chalmers AJ, Herold-Mende CC, Goldbrunner R, Niclou SP, Van Dyck E. A DNA repair and cell cycle gene expression signature in primary and recurrent glioblastoma: prognostic value and clinical implications. Cancer Research. PMID 30674534 DOI: 10.1158/0008-5472.CAN-18-2076  0.01
2018 Krell A, Wolter M, Stojcheva N, Hertler C, Liesenberg F, Zapatka M, Weller M, Malzkorn B, Reifenberger G. MiR-16-5p is frequently down-regulated in astrocytic gliomas and modulates glioma cell proliferation, apoptosis, and response to cytotoxic therapy. Neuropathology and Applied Neurobiology. PMID 30548945 DOI: 10.1111/nan.12532  0.01
2018 An Z, Knobbe-Thomsen CB, Wan X, Fan QW, Reifenberger G, Weiss WA. EGFR cooperates with EGFRvIII to recruit macrophages in glioblastoma. Cancer Research. PMID 30401716 DOI: 10.1158/0008-5472.CAN-17-3551  0.01
2018 Vettermann FJ, Felsberg J, Reifenberger G, Hasselblatt M, Forbrig R, Berding G, la Fougère C, Galldiks N, Schittenhelm J, Weis J, Albert NL, Schüller U. Characterization of Diffuse Gliomas With Histone H3-G34 Mutation by MRI and Dynamic 18F-FET PET. Clinical Nuclear Medicine. 43: 895-898. PMID 30358620 DOI: 10.1097/RLU.0000000000002300  0.01
2018 Brat DJ, Aldape K, Colman H, Holland EC, Louis DN, Jenkins RB, Kleinschmidt-DeMasters BK, Perry A, Reifenberger G, Stupp R, von Deimling A, Weller M. cIMPACT-NOW update 3: recommended diagnostic criteria for "Diffuse astrocytic glioma, IDH-wildtype, with molecular features of glioblastoma, WHO grade IV". Acta Neuropathologica. PMID 30259105 DOI: 10.1007/s00401-018-1913-0  0.01
2018 Forget A, Martignetti L, Puget S, Calzone L, Brabetz S, Picard D, Montagud A, Liva S, Sta A, Dingli F, Arras G, Rivera J, Loew D, Besnard A, Lacombe J, ... ... Reifenberger G, et al. Aberrant ERBB4-SRC Signaling as a Hallmark of Group 4 Medulloblastoma Revealed by Integrative Phosphoproteomic Profiling. Cancer Cell. 34: 379-395.e7. PMID 30205043 DOI: 10.1016/j.ccell.2018.08.002  0.01
2018 Capper D, Engel NW, Stichel D, Lechner M, Glöss S, Schmid S, Kölsche C, Schrimpf D, Niesen J, Wefers AK, Jones DTW, Sill M, Weigert O, Ligon KL, Olar A, ... ... Reifenberger G, et al. Correction to: DNA methylation-based reclassification of olfactory neuroblastoma. Acta Neuropathologica. PMID 30094618 DOI: 10.1007/s00401-018-1887-y  0.01
2018 Witt H, Gramatzki D, Hentschel B, Pajtler KW, Felsberg J, Schackert G, Löffler M, Capper D, Sahm F, Sill M, von Deimling A, Kool M, Herrlinger U, Westphal M, Pietsch T, ... Reifenberger G, et al. DNA methylation-based classification of ependymomas in adulthood: implications for diagnosis and treatment. Neuro-Oncology. PMID 30053291 DOI: 10.1093/neuonc/noy118  0.01
2018 Zhang L, Sorensen M, Kristensen BW, Reifenberger G, McIntyre TM, Lin F. The oncometabolite D-2-hydroxyglutarate is an intercellular mediator in IDH-mutant gliomas that inhibits both complement and T cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30006485 DOI: 10.1158/1078-0432.CCR-17-3855  0.01
2018 Gröbner SN, Worst BC, Weischenfeldt J, Buchhalter I, Kleinheinz K, Rudneva VA, Johann PD, Balasubramanian GP, Segura-Wang M, Brabetz S, Bender S, Hutter B, Sturm D, Pfaff E, Hübschmann D, ... ... Reifenberger G, et al. Author Correction: The landscape of genomic alterations across childhood cancers. Nature. PMID 29875405 DOI: 10.1038/s41586-018-0167-2  0.01
2018 Suwala AK, Koch K, Rios DH, Aretz P, Uhlmann C, Ogorek I, Felsberg J, Reifenberger G, Köhrer K, Deenen R, Steiger HJ, Kahlert UD, Maciaczyk J. Inhibition of Wnt/beta-catenin signaling downregulates expression of aldehyde dehydrogenase isoform 3A1 (ALDH3A1) to reduce resistance against temozolomide in glioblastoma . Oncotarget. 9: 22703-22716. PMID 29854309 DOI: 10.18632/oncotarget.25210  0.01
2018 Capper D, Engel NW, Stichel D, Lechner M, Glöss S, Schmid S, Koelsche C, Schrimpf D, Niesen J, Wefers AK, Jones DTW, Sill M, Weigert O, Ligon KL, Olar A, ... ... Reifenberger G, et al. DNA methylation-based reclassification of olfactory neuroblastoma. Acta Neuropathologica. PMID 29730775 DOI: 10.1007/s00401-018-1854-7  0.01
2018 Ballmann C, Thiel A, Korah HE, Reis AC, Saeger W, Stepanow S, Köhrer K, Reifenberger G, Knobbe-Thomsen CB, Knappe UJ, Scholl UI. Mutations in Pituitary Cushing Adenomas-Targeted Analysis by Next-Generation Sequencing. Journal of the Endocrine Society. 2: 266-278. PMID 29600293 DOI: 10.1210/js.2017-00364  0.01
2018 Happold C, Stojcheva N, Silginer M, Weiss T, Roth P, Reifenberger G, Weller M. Transcriptional control of O-methylguanine DNA methyltransferase expression and temozolomide resistance in glioblastoma. Journal of Neurochemistry. PMID 29480969 DOI: 10.1111/jnc.14326  0.01
2018 Aldape K, Amin SB, Ashley DM, Barnholtz-Sloan JS, Bates AJ, Beroukhim R, Bock C, Brat DJ, Claus EB, Costello JF, de Groot JF, Finocchiaro G, French PJ, Gan HK, Griffith B, ... ... Reifenberger G, et al. Glioma Through the Looking GLASS: Molecular Evolution of Diffuse Gliomas and the Glioma Longitudinal AnalySiS Consortium. Neuro-Oncology. PMID 29432615 DOI: 10.1093/neuonc/noy020  0.01
2018 Johann PD, Bens S, Oyen F, Wagener R, Giannini C, Perry A, Raisanen JM, Reis GF, Nobusawa S, Arita K, Felsberg J, Reifenberger G, Agaimy A, Buslei R, Capper D, et al. Sellar Region Atypical Teratoid/Rhabdoid Tumors (ATRT) in Adults Display DNA Methylation Profiles of the ATRT-MYC Subgroup. The American Journal of Surgical Pathology. PMID 29324471 DOI: 10.1097/PAS.0000000000001023  0.01
2017 Rudà R, Reifenberger G, Frappaz D, Pfister SM, Laprie A, Santarius T, Roth P, Tonn JC, Soffietti R, Weller M, Moyal EC. EANO guidelines for the diagnosis and treatment of ependymal tumors. Neuro-Oncology. PMID 29194500 DOI: 10.1093/neuonc/nox166  0.01
2017 Kessler T, Sahm F, Sadik A, Stichel D, Hertenstein A, Reifenberger G, Zacher A, Sabel M, Tabatabai G, Steinbach J, Sure U, Krex D, Grosu AL, Bewerunge-Hudler M, Jones D, et al. Molecular differences in IDH wildtype glioblastoma according to MGMT promoter methylation. Neuro-Oncology. PMID 29016808 DOI: 10.1093/neuonc/nox160  0.01
2017 Cimino PJ, Zager M, McFerrin L, Wirsching HG, Bolouri H, Hentschel B, von Deimling A, Jones D, Reifenberger G, Weller M, Holland EC. Multidimensional scaling of diffuse gliomas: application to the 2016 World Health Organization classification system with prognostically relevant molecular subtype discovery. Acta Neuropathologica Communications. 5: 39. PMID 28532485 DOI: 10.1186/s40478-017-0443-7  0.01
2017 van den Bruck R, Weil PP, Ziegenhals T, Schreiner P, Juranek S, Gödde D, Vogel S, Schuster F, Orth V, Dörner J, Pembaur D, Röper M, Störkel S, Zirngibl H, Wirth S, ... ... Reifenberger G, et al. Abstracts of the 52nd Workshop for Pediatric Research : Frankfurt, Germany. 27-28 October 2016. Molecular and Cellular Pediatrics. 4: 5. PMID 28516419 DOI: 10.1186/s40348-017-0071-0  0.01
2017 Barrantes-Freer A, Engel AS, Rodríguez-Villagra OA, Winkler A, Bergmann M, Mawrin C, Kuempfel T, Pellkofer H, Metz I, Bleckmann A, Hernández-Durán S, Schippling S, Rushing EJ, Frank S, Glatzel M, ... ... Reifenberger G, et al. Diagnostic Red Flags: Steroid-Treated Malignant CNS Lymphoma Mimicking Autoimmune Inflammatory Demyelination. Brain Pathology (Zurich, Switzerland). PMID 28213912 DOI: 10.1111/bpa.12496  0.01
2017 Florea AM, Varghese E, McCallum JE, Mahgoub S, Helmy I, Varghese S, Gopinath N, Sass S, Theis FJ, Reifenberger G, Büsselberg D. Calcium-regulatory proteins as modulators of chemotherapy in human neuroblastoma. Oncotarget. PMID 28206967 DOI: 10.18632/oncotarget.15283  0.01
2017 Heß K, Purrucker J, Hegenbart U, Brokinkel B, Berndt R, Keyvani K, Monoranu CM, Löhr M, Reifenberger G, Munoz-Bendix C, Kalla J, Groß J, Schick U, Kollmer J, Klapper W, et al. Cerebral amyloidoma is characterized by B-cell clonality and a stable clinical course. Brain Pathology (Zurich, Switzerland). PMID 28160367 DOI: 10.1111/bpa.12493  0.01
2017 Happold C, Felsberg J, Clarke J, Soffietti R, Marosi C, Krex D, Ducray F, Hau P, Reijneveld J, Weyerbrock A, Wick A, Reardon D, Glas M, Razis E, Herrlinger U, ... ... Reifenberger G, et al. ACTR-23. MOLECULAR GENETIC, HOST-DERIVED AND CLINICAL DETERMINANTS OF LONG-TERM SURVIVAL IN GLIOBLASTOMA: FIRST RESULTS FROM THE BRAIN TUMOR FUNDERS’ COLLABORATIVE CONSORTIUM Neuro-Oncology. 19: vi5-vi6. DOI: 10.1093/neuonc/nox168.018  0.01
2016 Reifenberger G, Wirsching HG, Knobbe-Thomsen CB, Weller M. Advances in the molecular genetics of gliomas - implications for classification and therapy. Nature Reviews. Clinical Oncology. PMID 28031556 DOI: 10.1038/nrclinonc.2016.204  0.01
2016 Louis DN, Aldape K, Brat DJ, Capper D, Ellison DW, Hawkins C, Paulus W, Perry A, Reifenberger G, Figarella-Branger D, Wesseling P, Batchelor TT, Gregory Cairncross J, Pfister SM, Rutkowski S, et al. cIMPACT-NOW (the consortium to inform molecular and practical approaches to CNS tumor taxonomy): a new initiative in advancing nervous system tumor classification. Brain Pathology (Zurich, Switzerland). PMID 27997995 DOI: 10.1111/bpa.12457  0.01
2016 Louis DN, Aldape K, Brat DJ, Capper D, Ellison DW, Hawkins C, Paulus W, Perry A, Reifenberger G, Figarella-Branger D, Wesseling P, Batchelor TT, Cairncross JG, Pfister SM, Rutkowski S, et al. Announcing cIMPACT-NOW: the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy. Acta Neuropathologica. PMID 27909809 DOI: 10.1007/s00401-016-1646-x  0.01
2016 Mangani D, Weller M, Seyed Sadr E, Willscher E, Seystahl K, Reifenberger G, Tabatabai G, Binder H, Schneider H. Limited role for transforming growth factor-β pathway activation-mediated escape from VEGF inhibition in murine glioma models. Neuro-Oncology. PMID 27286797 DOI: 10.1093/neuonc/now112  0.01
2016 Masui K, Mischel PS, Reifenberger G. Molecular classification of gliomas. Handbook of Clinical Neurology. 134: 97-120. PMID 26948350 DOI: 10.1016/B978-0-12-802997-8.00006-2  0.01
2016 Zacher A, Kaulich K, Stepanow S, Wolter M, Köhrer K, Felsberg J, Malzkorn B, Reifenberger G. Molecular diagnostics of gliomas using next generation sequencing of a glioma-tailored gene panel. Brain Pathology (Zurich, Switzerland). PMID 26919320 DOI: 10.1111/bpa.12367  0.01
2016 Stojcheva N, Schechtmann G, Sass S, Roth P, Florea AM, Stefanski A, Stühler K, Wolter M, Müller NS, Theis FJ, Weller M, Reifenberger G, Happold C. MicroRNA-138 promotes acquired alkylator resistance in glioblastoma by targeting the Bcl-2-interacting mediator BIM. Oncotarget. PMID 26887050 DOI: 10.18632/oncotarget.7346  0.01
2016 Suchorska B, Weller M, Tabatabai G, Senft C, Hau P, Sabel MC, Herrlinger U, Ketter R, Schlegel U, Marosi C, Reifenberger G, Wick W, Tonn JC, Wirsching HG. Complete resection of contrast-enhancing tumor volume is associated with improved survival in recurrent glioblastoma-results from the DIRECTOR trial. Neuro-Oncology. PMID 26823503 DOI: 10.1093/neuonc/nov326  0.01
2016 Herrlinger U, Jones DT, Glas M, Hattingen E, Gramatzki D, Stuplich M, Felsberg J, Bähr O, Gielen GH, Simon M, Wiewrodt D, Schabet M, Hovestadt V, Capper D, Steinbach JP, ... ... Reifenberger G, et al. Erratum to: Gliomatosis cerebri: no evidence for a separate brain tumor entity. Acta Neuropathologica. PMID 26744347 DOI: 10.1007/s00401-015-1523-z  0.01
2016 Codó P, Weller M, Kaulich K, Schraivogel D, Silginer M, Reifenberger G, Meister G, Roth P. Control of glioma cell migration and invasiveness by GDF-15. Oncotarget. PMID 26741507 DOI: 10.18632/oncotarget.6816  0.01
2015 Weller M, Wick W, Aldape K, Brada M, Berger M, Pfister SM, Nishikawa R, Rosenthal M, Wen PY, Stupp R, Reifenberger G. Glioma. Nature Reviews. Disease Primers. 1: 15017. PMID 27188790 DOI: 10.1038/nrdp.2015.17  0.01
2015 Zuckermann M, Hovestadt V, Knobbe-Thomsen CB, Zapatka M, Northcott PA, Schramm K, Belic J, Jones DT, Tschida B, Moriarity B, Largaespada D, Roussel MF, Korshunov A, Reifenberger G, Pfister SM, et al. Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling. Nature Communications. 6: 7391. PMID 26067104 DOI: 10.1038/ncomms8391  0.01
2015 Ahmad-Nejad P, Duda A, Sucker A, Werner M, Bronsert P, Stickeler E, Reifenberger G, Malzkorn B, Oberländer M, Habermann JK, Bruch HP, Linnebacher M, Schadendorf D, Neumaier M. Assessing quality and functionality of DNA isolated from FFPE tissues through external quality assessment in tissue banks. Clinical Chemistry and Laboratory Medicine : Cclm / Fescc. 53: 1927-34. PMID 26053008 DOI: 10.1515/cclm-2014-1202  0.01
2015 Aldape K, Zadeh G, Mansouri S, Reifenberger G, von Deimling A. Glioblastoma: pathology, molecular mechanisms and markers. Acta Neuropathologica. 129: 829-48. PMID 25943888 DOI: 10.1007/s00401-015-1432-1  0.01
2015 Kamp MA, Felsberg J, Sadat H, Kuzibaev J, Steiger HJ, Rapp M, Reifenberger G, Dibué M, Sabel M. 5-ALA-induced fluorescence behavior of reactive tissue changes following glioblastoma treatment with radiation and chemotherapy. Acta Neurochirurgica. 157: 207-13; discussion 2. PMID 25547719 DOI: 10.1007/s00701-014-2313-4  0.01
2014 Henze AT, Garvalov BK, Seidel S, Cuesta AM, Ritter M, Filatova A, Foss F, Dopeso H, Essmann CL, Maxwell PH, Reifenberger G, Carmeliet P, Acker-Palmer A, Acker T. Loss of PHD3 allows tumours to overcome hypoxic growth inhibition and sustain proliferation through EGFR. Nature Communications. 5: 5582. PMID 25420773 DOI: 10.1038/ncomms6582  0.01
2014 Ahmad M, Frei K, Willscher E, Stefanski A, Kaulich K, Roth P, Stühler K, Reifenberger G, Binder H, Weller M. How stemlike are sphere cultures from long-term cancer cell lines? Lessons from mouse glioma models. Journal of Neuropathology and Experimental Neurology. 73: 1062-77. PMID 25289892 DOI: 10.1097/NEN.0000000000000130  0.01
2014 Weller M, van den Bent M, Hopkins K, Tonn JC, Stupp R, Falini A, Cohen-Jonathan-Moyal E, Frappaz D, Henriksson R, Balana C, Chinot O, Ram Z, Reifenberger G, Soffietti R, Wick W, et al. EANO guideline for the diagnosis and treatment of anaplastic gliomas and glioblastoma. The Lancet. Oncology. 15: e395-403. PMID 25079102 DOI: 10.1016/S1470-2045(14)70011-7  0.01
2014 Tigges J, Krutmann J, Fritsche E, Haendeler J, Schaal H, Fischer JW, Kalfalah F, Reinke H, Reifenberger G, Stühler K, Ventura N, Gundermann S, Boukamp P, Boege F. The hallmarks of fibroblast ageing. Mechanisms of Ageing and Development. 138: 26-44. PMID 24686308 DOI: 10.1016/j.mad.2014.03.004  0.01
2014 Happold C, Roth P, Silginer M, Florea AM, Lamszus K, Frei K, Deenen R, Reifenberger G, Weller M. Interferon-β induces loss of spherogenicity and overcomes therapy resistance of glioblastoma stem cells. Molecular Cancer Therapeutics. 13: 948-61. PMID 24526161 DOI: 10.1158/1535-7163.MCT-13-0772  0.01
2014 Wirsching HG, Krishnan S, Florea AM, Frei K, Krayenbühl N, Hasenbach K, Reifenberger G, Weller M, Tabatabai G. Thymosin β 4 gene silencing decreases stemness and invasiveness in glioblastoma. Brain : a Journal of Neurology. 137: 433-48. PMID 24355709 DOI: 10.1093/brain/awt333  0.01
2014 Delic S, Lottmann N, Stelzl A, Liesenberg F, Wolter M, Götze S, Zapatka M, Shiio Y, Sabel MC, Felsberg J, Reifenberger G, Riemenschneider MJ. MiR-328 promotes glioma cell invasion via SFRP1-dependent Wnt-signaling activation. Neuro-Oncology. 16: 179-90. PMID 24305703 DOI: 10.1093/neuonc/not164  0.01
2014 Langen KJ, Rapp M, Galldiks N, Reifenberger G, Floeth FW. Reply: discriminating ability of (18)F-FET PET for several cerebral neoplastic lesions. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 55: 176. PMID 24198386 DOI: 10.2967/jnumed.113.134007  0.01
2013 Fan QW, Cheng CK, Gustafson WC, Charron E, Zipper P, Wong RA, Chen J, Lau J, Knobbe-Thomsen C, Weller M, Jura N, Reifenberger G, Shokat KM, Weiss WA. EGFR phosphorylates tumor-derived EGFRvIII driving STAT3/5 and progression in glioblastoma. Cancer Cell. 24: 438-49. PMID 24135280 DOI: 10.1016/j.ccr.2013.09.004  0.01
2013 Tiebel N, Lichota A, Scharbrodt W, Foerster AF, Toedt C, Reifenberger G, Malzkorn B. Intradural, extramedullary anaplastic astrocytoma arising from the first sacral nerve root. Jama Neurology. 70: 1450-1. PMID 24042468 DOI: 10.1001/2013.jamaneurol.368  0.01
2013 Hoell JI, Gombert M, Bartenhagen C, Ginzel S, Husemann P, Felsberg J, Reifenberger G, Eggert A, Dugas M, Schönberger S, Borkhardt A, Fischer U. Whole-genome paired-end analysis confirms remarkable genomic stability of atypical teratoid/rhabdoid tumors. Genes, Chromosomes & Cancer. 52: 983-5. PMID 23929726 DOI: 10.1002/gcc.22092  0.01
2013 Weller M, Pfister SM, Wick W, Hegi ME, Reifenberger G, Stupp R. Molecular neuro-oncology in clinical practice: a new horizon. The Lancet. Oncology. 14: e370-9. PMID 23896276 DOI: 10.1016/S1470-2045(13)70168-2  0.01
2013 Rapp M, Heinzel A, Galldiks N, Stoffels G, Felsberg J, Ewelt C, Sabel M, Steiger HJ, Reifenberger G, Beez T, Coenen HH, Floeth FW, Langen KJ. Diagnostic performance of 18F-FET PET in newly diagnosed cerebral lesions suggestive of glioma. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 54: 229-35. PMID 23232275 DOI: 10.2967/jnumed.112.109603  0.01
2012 Weller M, Stupp R, Hegi ME, van den Bent M, Tonn JC, Sanson M, Wick W, Reifenberger G. Personalized care in neuro-oncology coming of age: why we need MGMT and 1p/19q testing for malignant glioma patients in clinical practice. Neuro-Oncology. 14: iv100-8. PMID 23095825 DOI: 10.1093/neuonc/nos206  0.01
2012 Schüle R, Dictus C, Campos B, Wan F, Felsberg J, Ahmadi R, Centner FS, Grabe N, Reifenberger G, Bermejo JL, Unterberg A, Herold-Mende C. Potential canonical wnt pathway activation in high-grade astrocytomas. Thescientificworldjournal. 2012: 697313. PMID 22919349 DOI: 10.1100/2012/697313  0.01
2012 Happold C, Roth P, Wick W, Schmidt N, Florea AM, Silginer M, Reifenberger G, Weller M. Distinct molecular mechanisms of acquired resistance to temozolomide in glioblastoma cells. Journal of Neurochemistry. 122: 444-55. PMID 22564186 DOI: 10.1111/j.1471-4159.2012.07781.x  0.01
2012 Stummer W, Meinel T, Ewelt C, Martus P, Jakobs O, Felsberg J, Reifenberger G. Prospective cohort study of radiotherapy with concomitant and adjuvant temozolomide chemotherapy for glioblastoma patients with no or minimal residual enhancing tumor load after surgery. Journal of Neuro-Oncology. 108: 89-97. PMID 22307805 DOI: 10.1007/s11060-012-0798-3  0.01
2012 Kamp MA, Grosser P, Felsberg J, Slotty PJ, Steiger HJ, Reifenberger G, Sabel M. 5-aminolevulinic acid (5-ALA)-induced fluorescence in intracerebral metastases: a retrospective study. Acta Neurochirurgica. 154: 223-8; discussion 22. PMID 22080159 DOI: 10.1007/s00701-011-1200-5  0.01
2012 Schmidt N, Windmann S, Reifenberger G, Riemenschneider MJ. DNA hypermethylation and histone modifications downregulate the candidate tumor suppressor gene RRP22 on 22q12 in human gliomas. Brain Pathology (Zurich, Switzerland). 22: 17-25. PMID 21631628 DOI: 10.1111/j.1750-3639.2011.00507.x  0.01
2011 Glas M, Bähr O, Felsberg J, Rasch K, Wiewrodt D, Schabet M, Simon M, Urbach H, Steinbach JP, Rieger J, Fimmers R, Bamberg M, Nägele T, Reifenberger G, Weller M, et al. NOA-05 phase 2 trial of procarbazine and lomustine therapy in gliomatosis cerebri. Annals of Neurology. 70: 445-53. PMID 21710625 DOI: 10.1002/ana.22478  0.01
2011 Campos B, Centner FS, Bermejo JL, Ali R, Dorsch K, Wan F, Felsberg J, Ahmadi R, Grabe N, Reifenberger G, Unterberg A, Burhenne J, Herold-Mende C. Aberrant expression of retinoic acid signaling molecules influences patient survival in astrocytic gliomas. The American Journal of Pathology. 178: 1953-64. PMID 21514413 DOI: 10.1016/j.ajpath.2011.01.051  0.01
2011 Wan F, Herold-Mende C, Campos B, Centner FS, Dictus C, Becker N, Devens F, Mogler C, Felsberg J, Grabe N, Reifenberger G, Lichter P, Unterberg A, Bermejo JL, Ahmadi R. Association of stem cell-related markers and survival in astrocytic gliomas. Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. 16: 136-43. PMID 21323603 DOI: 10.3109/1354750X.2010.536256  0.01
2011 Floeth FW, Sabel M, Ewelt C, Stummer W, Felsberg J, Reifenberger G, Steiger HJ, Stoffels G, Coenen HH, Langen KJ. Comparison of (18)F-FET PET and 5-ALA fluorescence in cerebral gliomas. European Journal of Nuclear Medicine and Molecular Imaging. 38: 731-41. PMID 21153408 DOI: 10.1007/s00259-010-1690-z  0.01
2011 Campos B, Bermejo JL, Han L, Felsberg J, Ahmadi R, Grabe N, Reifenberger G, Unterberg A, Herold-Mende C. Expression of nuclear receptor corepressors and class I histone deacetylases in astrocytic gliomas. Cancer Science. 102: 387-92. PMID 21143702 DOI: 10.1111/j.1349-7006.2010.01792.x  0.01
2010 Riemenschneider MJ, Hegi ME, Reifenberger G. MGMT promoter methylation in malignant gliomas. Targeted Oncology. 5: 161-5. PMID 20725792 DOI: 10.1007/s11523-010-0153-6  0.01
2010 Korshunov A, Remke M, Werft W, Benner A, Ryzhova M, Witt H, Sturm D, Wittmann A, Schöttler A, Felsberg J, Reifenberger G, Rutkowski S, Scheurlen W, Kulozik AE, von Deimling A, et al. Adult and pediatric medulloblastomas are genetically distinct and require different algorithms for molecular risk stratification. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: 3054-60. PMID 20479417 DOI: 10.1200/JCO.2009.25.7121  0.01
2010 Salber D, Stoffels G, Oros-Peusquens AM, Shah NJ, Reifenberger G, Hamacher K, Coenen HH, Langen KJ. Comparison of O-(2-18F-fluoroethyl)-L-tyrosine and L-3H-methionine uptake in cerebral hematomas. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 51: 790-7. PMID 20395334 DOI: 10.2967/jnumed.109.071423  0.01
2010 Hudson TJ, Anderson W, Artez A, Barker AD, Bell C, Bernabé RR, Bhan MK, Calvo F, Eerola I, Gerhard DS, Guttmacher A, Guyer M, Hemsley FM, Jennings JL, ... ... Reifenberger G, et al. International network of cancer genome projects. Nature. 464: 993-8. PMID 20393554 DOI: 10.1038/nature08987  0.01
2010 Grzendowski M, Wolter M, Riemenschneider MJ, Knobbe CB, Schlegel U, Meyer HE, Reifenberger G, Stühler K. Differential proteome analysis of human gliomas stratified for loss of heterozygosity on chromosomal arms 1p and 19q. Neuro-Oncology. 12: 243-56. PMID 20167812 DOI: 10.1093/neuonc/nop025  0.01
2010 Felsberg J, Wolter M, Seul H, Friedensdorf B, Göppert M, Sabel MC, Reifenberger G. Rapid and sensitive assessment of the IDH1 and IDH2 mutation status in cerebral gliomas based on DNA pyrosequencing. Acta Neuropathologica. 119: 501-7. PMID 20131059 DOI: 10.1007/s00401-010-0647-4  0.01
2010 Weller M, Stupp R, Reifenberger G, Brandes AA, van den Bent MJ, Wick W, Hegi ME. MGMT promoter methylation in malignant gliomas: ready for personalized medicine? Nature Reviews. Neurology. 6: 39-51. PMID 19997073 DOI: 10.1038/nrneurol.2009.197  0.01
2010 Barski D, Wolter M, Reifenberger G, Riemenschneider MJ. Hypermethylation and transcriptional downregulation of the TIMP3 gene is associated with allelic loss on 22q12.3 and malignancy in meningiomas. Brain Pathology (Zurich, Switzerland). 20: 623-31. PMID 19922547 DOI: 10.1111/j.1750-3639.2009.00340.x  0.01
2009 Götze S, Feldhaus V, Traska T, Wolter M, Reifenberger G, Tannapfel A, Kuhnen C, Martin D, Müller O, Sievers S. ECRG4 is a candidate tumor suppressor gene frequently hypermethylated in colorectal carcinoma and glioma. Bmc Cancer. 9: 447. PMID 20017917 DOI: 10.1186/1471-2407-9-447  0.01
2009 Felsberg J, Rapp M, Loeser S, Fimmers R, Stummer W, Goeppert M, Steiger HJ, Friedensdorf B, Reifenberger G, Sabel MC. Prognostic significance of molecular markers and extent of resection in primary glioblastoma patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 6683-93. PMID 19861461 DOI: 10.1158/1078-0432.CCR-08-2801  0.01
2003 Wolter M, Scharwächter C, Reifenberger J, Koch A, Pietsch T, Reifenberger G. Absence of detectable alterations in the putative tumor suppressor gene BTRC in cerebellar medulloblastomas and cutaneous basal cell carcinomas. Acta Neuropathologica. 106: 287-90. PMID 12898158 DOI: 10.1007/s00401-003-0745-7  0.01
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