Hans-Peter Hartung - Publications

Affiliations: 
Department of Neurology Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Nordrhein-Westfalen, Germany 

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Year Citation  Score
2020 Bril V, Hartung HP, Lawo JP, Durn BL, Mielke O. Electrophysiological testing in chronic inflammatory demyelinating polyneuropathy patients treated with subcutaneous immunoglobulin: The Polyneuropathy And Treatment with Hizentra (PATH) study. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. PMID 33039291 DOI: 10.1016/J.Clinph.2020.09.001  0.342
2020 Breitkopf K, Aytulun A, Förster M, Kraus B, Turowski B, Huppert D, Goebels N, Hefter H, Aktas O, Metz I, Brück W, Reifenberger G, Hartung HP, Albrecht P. Case Report: A Case of Severe Clinical Deterioration in a Patient With Multiple Sclerosis. Frontiers in Neurology. 11: 782. PMID 32973648 DOI: 10.3389/Fneur.2020.00782  0.367
2020 Graf J, Albrecht P, Goebels N, Aktas O, Hartung HP. [Erratum to: Ocrelizumab for treatment of multiple sclerosis]. Der Nervenarzt. PMID 32725489 DOI: 10.1007/S00115-020-00956-3  0.341
2020 Sorensen PS, Sellebjerg F, Hartung HP, Montalban X, Comi G, Tintoré M. The apparently milder course of multiple sclerosis: changes in the diagnostic criteria, therapy and natural history. Brain : a Journal of Neurology. PMID 32710096 DOI: 10.1093/Brain/Awaa145  0.4
2020 Mares J, Hartung HP. Multiple sclerosis and COVID-19. Biomedical Papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia. PMID 32686774 DOI: 10.5507/Bp.2020.033  0.34
2020 Ghezzi A, Amato MP, Edan G, Hartung HP, Havrdová EK, Kappos L, Montalban X, Pozzilli C, Sorensen PS, Trojano M, Vermersch P, Comi G. The introduction of new medications in pediatric multiple sclerosis: Open issues and challenges. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458520930620. PMID 32539596 DOI: 10.1177/1352458520930620  0.351
2020 Graf J, Albrecht P, Goebels N, Aktas O, Hartung HP. [Ocrelizumab for treatment of multiple sclerosis]. Der Nervenarzt. PMID 32524163 DOI: 10.1007/S00115-020-00937-6  0.385
2020 Hartung HP. Ocrelizumab shorter infusion: Primary results from the ENSEMBLE PLUS substudy in patients with MS. Neurology(R) Neuroimmunology & Neuroinflammation. 7. PMID 32503093 DOI: 10.1212/Nxi.0000000000000807  0.335
2020 Bittner S, Steffen F, Uphaus T, Muthuraman M, Fleischer V, Salmen A, Luessi F, Berthele A, Klotz L, Meuth SG, Bayas A, Paul F, Hartung HP, Linker R, Heesen C, et al. Clinical implications of serum neurofilament in newly diagnosed MS patients: A longitudinal multicentre cohort study. Ebiomedicine. 56: 102807. PMID 32460167 DOI: 10.1016/J.Ebiom.2020.102807  0.343
2020 Landmeyer NC, Bürkner PC, Wiendl H, Ruck T, Hartung HP, Holling H, Meuth SG, Johnen A. Disease-modifying treatments and cognition in relapsing-remitting multiple sclerosis: A meta-analysis. Neurology. 94: e2373-e2383. PMID 32430312 DOI: 10.1212/Wnl.0000000000009522  0.333
2020 Wienemann T, Müller AK, MacKenzie C, Bielor C, Weyers V, Aktas O, Hartung HP, Kremer D. Cryptococcal meningoencephalitis in an IgG-deficient patient with multiple sclerosis on fingolimod therapy for more than five years - case report. Bmc Neurology. 20: 158. PMID 32340606 DOI: 10.1186/S12883-020-01741-0  0.342
2020 Kremer D, Weyers V, Gruchot J, Göttle P, Hartung HP, Perron H, Küry P. Meeting report: "Human endogenous retroviruses: HERVs or transposable elements in autoimmune, chronic inflammatory and degenerative diseases or cancer", Lyon, France, november 5th and 6th 2019 - an MS scientist's digest. Multiple Sclerosis and Related Disorders. 42: 102068. PMID 32302965 DOI: 10.1016/J.Msard.2020.102068  0.302
2019 Bar-Or A, Pender MP, Khanna R, Steinman L, Hartung HP, Maniar T, Croze E, Aftab BT, Giovannoni G, Joshi MJ. Epstein-Barr Virus in Multiple Sclerosis: Theory and Emerging Immunotherapies. Trends in Molecular Medicine. PMID 31862243 DOI: 10.1016/J.Molmed.2019.11.003  0.365
2019 Haas J, Jeffery D, Silva D, Meier DP, Meinert R, Cohen J, Hartung HP. Early initiation of fingolimod reduces the rate of severe relapses over the long term: Post hoc analysis from the FREEDOMS, FREEDOMS II, and TRANSFORMS studies. Multiple Sclerosis and Related Disorders. 36: 101335. PMID 31557679 DOI: 10.1016/J.Msard.2019.07.011  0.33
2019 Penner IK, Hartung HP. The dark side of the moon: looking beyond beneficial effects of cannabis use in multiple sclerosis. Brain : a Journal of Neurology. 142: 2552-2555. PMID 31497861 DOI: 10.1093/Brain/Awz234  0.311
2019 Cree BAC, Bennett JL, Kim HJ, Weinshenker BG, Pittock SJ, Wingerchuk DM, Fujihara K, Paul F, Cutter GR, Marignier R, Green AJ, Aktas O, Hartung HP, Lublin FD, Drappa J, et al. Inebilizumab for the treatment of neuromyelitis optica spectrum disorder (N-MOmentum): a double-blind, randomised placebo-controlled phase 2/3 trial. Lancet (London, England). PMID 31495497 DOI: 10.1016/S0140-6736(19)31817-3  0.332
2019 Sinnecker T, Hadisurya J, Schneider-Hohendorf T, Schwab N, Wrede K, Gembruch O, Gold R, Hellwig K, Pilgram-Pastor S, Adams O, Albrecht P, Hartung HP, Aktas O, Kraemer M. Extensive immune reconstitution inflammatory syndrome in Fingolimod-associated PML: a case report with 7 Tesla MRI data. Bmc Neurology. 19: 190. PMID 31399069 DOI: 10.1186/S12883-019-1407-2  0.321
2019 Gruchot J, Weyers V, Göttle P, Förster M, Hartung HP, Küry P, Kremer D. The Molecular Basis for Remyelination Failure in Multiple Sclerosis. Cells. 8. PMID 31382620 DOI: 10.3390/Cells8080825  0.374
2019 Cadavid D, Mellion M, Hupperts R, Edwards KR, Calabresi PA, Drulović J, Giovannoni G, Hartung HP, Arnold DL, Fisher E, Rudick R, Mi S, Chai Y, Li J, Zhang Y, et al. Safety and efficacy of opicinumab in patients with relapsing multiple sclerosis (SYNERGY): a randomised, placebo-controlled, phase 2 trial. The Lancet. Neurology. PMID 31285147 DOI: 10.1016/S1474-4422(19)30137-1  0.364
2019 Kremer D, Gruchot J, Weyers V, Oldemeier L, Göttle P, Healy L, Ho Jang J, Kang T Xu Y, Volsko C, Dutta R, Trapp BD, Perron H, Hartung HP, Küry P. pHERV-W envelope protein fuels microglial cell-dependent damage of myelinated axons in multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 31213545 DOI: 10.1073/Pnas.1901283116  0.377
2019 Phelps R, Winston JA, Wynn D, Habek M, Hartung HP, Havrdová EK, Markowitz GS, Margolin DH, Rodriguez CE, Baker DP, Coles AJ. Incidence, management, and outcomes of autoimmune nephropathies following alemtuzumab treatment in patients with multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458519841829. PMID 30986126 DOI: 10.1177/1352458519841829  0.365
2019 Schweitzer F, Laurent S, Fink GR, Barnett MH, Reddel S, Hartung HP, Warnke C. Age and the risks of high-efficacy disease modifying drugs in multiple sclerosis. Current Opinion in Neurology. PMID 30985373 DOI: 10.1097/Wco.0000000000000701  0.346
2019 Cree BAC, Mares J, Hartung HP. Current therapeutic landscape in multiple sclerosis: an evolving treatment paradigm. Current Opinion in Neurology. PMID 30985372 DOI: 10.1097/Wco.0000000000000700  0.342
2019 Prozorovski T, Ingwersen J, Lukas D, Göttle P, Koop B, Graf J, Schneider R, Franke K, Schumacher S, Britsch S, Hartung HP, Küry P, Berndt C, Aktas O. Regulation of sirtuin expression in autoimmune neuroinflammation: induction of SIRT1 in oligodendrocyte progenitor cells. Neuroscience Letters. PMID 30953735 DOI: 10.1016/J.Neulet.2019.04.007  0.365
2019 Kremer D, Göttle P, Flores-Rivera J, Hartung HP, Küry P. Remyelination in multiple sclerosis: from concept to clinical trials. Current Opinion in Neurology. PMID 30865009 DOI: 10.1097/Wco.0000000000000692  0.386
2019 Dietrich M, Aktas O, Hartung HP, Albrecht P. Assessing the anterior visual pathway in optic neuritis: recent experimental and clinical aspects. Current Opinion in Neurology. PMID 30694926 DOI: 10.1097/Wco.0000000000000675  0.359
2019 Zhu B, Calabresi PA, Giovanonni G, Kapoor R, Naismith R, Hartung H, Arnold DL, Wolstencroft P, Johnson K. 200 AFFINITY: opicinumab in a targeted population of MS patients Journal of Neurology, Neurosurgery, and Psychiatry. 90. DOI: 10.1136/Jnnp-2019-Abn-2.169  0.396
2018 Schira J, Heinen A, Poschmann G, Ziegler B, Hartung HP, Stühler K, Küry P. Secretome analysis of nerve repair mediating Schwann cells reveals Smad-dependent trophism. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201801799R. PMID 30592632 DOI: 10.1096/Fj.201801799R  0.311
2018 Kieseier BC, Mathey EK, Sommer C, Hartung HP. Immune-mediated neuropathies. Nature Reviews. Disease Primers. 4: 31. PMID 30310069 DOI: 10.1016/B978-012088592-3/50021-9  0.352
2018 Graf J, Ringelstein M, Lepka K, Schaller J, Quack H, Hartung HP, Aktas O, Albrecht P. Acute sarcoidosis in a multiple sclerosis patient after alemtuzumab treatment. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458518771276. PMID 30307371 DOI: 10.1177/1352458518771276  0.379
2018 Wray S, Havrdova E, Snydman DR, Arnold DL, Cohen JA, Coles AJ, Hartung HP, Selmaj KW, Weiner HL, Daizadeh N, Margolin DH, Chirieac MC, Compston DAS. Infection risk with alemtuzumab decreases over time: pooled analysis of 6-year data from the CAMMS223, CARE-MS I, and CARE-MS II studies and the CAMMS03409 extension study. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458518796675. PMID 30289355 DOI: 10.1177/1352458518796675  0.32
2018 Hughes R, Dalakas MC, Merkies I, Latov N, Léger JM, Nobile-Orazio E, Sobue G, Genge A, Cornblath D, Merschhemke M, Ervin CM, Agoropoulou C, Hartung HP. Oral fingolimod for chronic inflammatory demyelinating polyradiculoneuropathy (FORCIDP Trial): a double-blind, multicentre, randomised controlled trial. The Lancet. Neurology. PMID 30001923 DOI: 10.1016/S1474-4422(18)30202-3  0.367
2018 Lehmann HC, Compston A, Hartung HP. 150th anniversary of clinical description of multiple sclerosis: Leopold Ordenstein's legacy. Neurology. 90: 1011-1016. PMID 29807916 DOI: 10.1212/Wnl.0000000000005613  0.315
2018 Miller DH, Lublin FD, Sormani MP, Kappos L, Yaldizli Ö, Freedman MS, Cree BAC, Weiner HL, Lubetzki C, Hartung HP, Montalban X, Uitdehaag BMJ, MacManus DG, Yousry TA, Gandini Wheeler-Kingshott CAM, et al. Brain atrophy and disability worsening in primary progressive multiple sclerosis: insights from the INFORMS study. Annals of Clinical and Translational Neurology. 5: 346-356. PMID 29560379 DOI: 10.1002/Acn3.534  0.305
2018 Küry P, Nath A, Créange A, Dolei A, Marche P, Gold J, Giovannoni G, Hartung HP, Perron H. Human Endogenous Retroviruses in Neurological Diseases. Trends in Molecular Medicine. PMID 29551251 DOI: 10.1016/J.Molmed.2018.02.007  0.311
2018 Kapoor R, Ho PR, Campbell N, Chang I, Deykin A, Forrestal F, Lucas N, Yu B, Arnold DL, Freedman MS, Goldman MD, Hartung HP, Havrdová EK, Jeffery D, Miller A, et al. Effect of natalizumab on disease progression in secondary progressive multiple sclerosis (ASCEND): a phase 3, randomised, double-blind, placebo-controlled trial with an open-label extension. The Lancet. Neurology. PMID 29545067 DOI: 10.1016/S1474-4422(18)30069-3  0.376
2018 Dietrich M, Helling N, Hilla A, Heskamp A, Issberner A, Hildebrandt T, Kohne Z, Küry P, Berndt C, Aktas O, Fischer D, Hartung HP, Albrecht P. Early alpha-lipoic acid therapy protects from degeneration of the inner retinal layers and vision loss in an experimental autoimmune encephalomyelitis-optic neuritis model. Journal of Neuroinflammation. 15: 71. PMID 29514678 DOI: 10.1186/S12974-018-1111-Y  0.341
2018 Kieseier BC, Hartung HP. Progress in Recognizing and Treating Polyneuropathy. Deutsches Arzteblatt International. 115: 81-82. PMID 29478434 DOI: 10.3238/Arztebl.2018.0081  0.3
2018 Ingwersen J, De Santi L, Wingerath B, Graf J, Koop B, Schneider R, Hecker C, Schröter F, Bayer M, Engelke AD, Dietrich M, Albrecht P, Hartung HP, Annunziata P, Aktas O, et al. Nimodipine confers clinical improvement in two models of experimental autoimmune encephalomyelitis. Journal of Neurochemistry. PMID 29473171 DOI: 10.1111/Jnc.14324  0.371
2018 Leussink VI, Reifenberger J, Hartung H. Case of alopecia universalis associated with alemtuzumab treatment in MS Neurology - Neuroimmunology Neuroinflammation. 5: e454. DOI: 10.1212/Nxi.0000000000000454  0.361
2018 McCombe P, Boyko AN, DeSeze J, Hartung H, Havrdova E, Inshasi JS, Montalban X, Pozzilli C, Selmaj KW, Vermersch P, Melanson M, Daizadeh N, Rodriguez CE, Wijmeersch BV, Investigators T. 044 Durable clinical efficacy of alemtuzumab in patients with active rrms in the absence of continuous treatment: 7-year follow-up of CARE-MS I patients (Topaz Study) Journal of Neurology, Neurosurgery, and Psychiatry. 89. DOI: 10.1136/Jnnp-2018-Anzan.43  0.349
2017 Graf J, Leussink VI, Dehmel T, Ringelstein M, Goebels N, Adams O, MacKenzie CR, Warnke C, Feldt T, Lammerskitten A, Klotz L, Meuth S, Wiendl H, Hartung HP, Aktas O, et al. Infectious risk stratification in multiple sclerosis patients receiving immunotherapy. Annals of Clinical and Translational Neurology. 4: 909-914. PMID 29296620 DOI: 10.1002/Acn3.491  0.303
2017 van Schaik IN, Bril V, van Geloven N, Hartung HP, Lewis RA, Sobue G, Lawo JP, Praus M, Mielke O, Durn BL, Cornblath DR, Merkies ISJ. Subcutaneous immunoglobulin for maintenance treatment in chronic inflammatory demyelinating polyneuropathy (PATH): a randomised, double-blind, placebo-controlled, phase 3 trial. The Lancet. Neurology. PMID 29122523 DOI: 10.1016/S1474-4422(17)30378-2  0.323
2017 Coles AJ, Cohen JA, Fox EJ, Giovannoni G, Hartung HP, Havrdova E, Schippling S, Selmaj KW, Traboulsee A, Compston DAS, Margolin DH, Thangavelu K, Chirieac MC, Jody D, Xenopoulos P, et al. Alemtuzumab CARE-MS II 5-year follow-up: Efficacy and safety findings. Neurology. PMID 28835403 DOI: 10.1212/Wnl.0000000000004354  0.316
2017 Ehler J, Blechinger S, Rommer PS, Koball S, Mitzner S, Hartung HP, Leutmezer F, Sauer M, Zettl UK. Treatment of the First Acute Relapse Following Therapeutic Plasma Exchange in Formerly Glucocorticosteroid-Unresponsive Multiple Sclerosis Patients-A Multicenter Study to Evaluate Glucocorticosteroid Responsiveness. International Journal of Molecular Sciences. 18. PMID 28800066 DOI: 10.3390/Ijms18081749  0.364
2017 Fitzgerald KC, Munger KL, Hartung HP, Freedman MS, Montalbán X, Edan G, Wicklein EM, Radue EW, Kappos L, Pohl C, Ascherio A. Sodium intake and multiple sclerosis activity and progression in BENEFIT. Annals of Neurology. PMID 28556498 DOI: 10.1002/Ana.24965  0.339
2017 Link J, Ramanujam R, Auer M, Ryner M, Hässler S, Bachelet D, Mbogning C, Warnke C, Buck D, Hyldgaard Jensen PE, Sievers C, Ingenhoven K, Fissolo N, Lindberg R, Grummel V, ... ... Hartung HP, et al. Clinical practice of analysis of anti-drug antibodies against interferon beta and natalizumab in multiple sclerosis patients in Europe: A descriptive study of test results. Plos One. 12: e0170395. PMID 28170401 DOI: 10.1371/Journal.Pone.0170395  0.307
2016 Havla J, Warnke C, Derfuss T, Kappos L, Hartung HP, Hohlfeld R. Interdisciplinary Risk Management in the Treatment of Multiple Sclerosis. Deutsches Arzteblatt International. 113: 879-886. PMID 28130920 DOI: 10.3238/Arztebl.2016.0879  0.368
2016 Montalban X, Hauser SL, Kappos L, Arnold DL, Bar-Or A, Comi G, de Seze J, Giovannoni G, Hartung HP, Hemmer B, Lublin F, Rammohan KW, Selmaj K, Traboulsee A, Sauter A, et al. Ocrelizumab versus Placebo in Primary Progressive Multiple Sclerosis. The New England Journal of Medicine. PMID 28002688 DOI: 10.1056/Nejmoa1606468  0.343
2016 Hauser SL, Bar-Or A, Comi G, Giovannoni G, Hartung HP, Hemmer B, Lublin F, Montalban X, Rammohan KW, Selmaj K, Traboulsee A, Wolinsky JS, Arnold DL, Klingelschmitt G, Masterman D, et al. Ocrelizumab versus Interferon Beta-1a in Relapsing Multiple Sclerosis. The New England Journal of Medicine. PMID 28002679 DOI: 10.1056/Nejmoa1601277  0.305
2016 Winter M, Baksmeier C, Steckel J, Barman S, Malviya M, Harrer-Kuster M, Hartung HP, Goebels N. Dose-dependent inhibition of demyelination and microglia activation by IVIG. Annals of Clinical and Translational Neurology. 3: 828-843. PMID 27844029 DOI: 10.1002/Acn3.326  0.354
2016 Meyer Zu Horste G, Cordes S, Pfaff J, Mathys C, Mausberg AK, Bendszus M, Pham M, Hartung HP, Kieseier BC. Predicting the Response to Intravenous Immunoglobulins in an Animal Model of Chronic Neuritis. Plos One. 11: e0164099. PMID 27711247 DOI: 10.1371/Journal.Pone.0164099  0.323
2016 Schneider R, Koop B, Schröter F, Cline J, Ingwersen J, Berndt C, Hartung HP, Aktas O, Prozorovski T. Activation of Wnt signaling promotes hippocampal neurogenesis in experimental autoimmune encephalomyelitis. Molecular Neurodegeneration. 11: 53. PMID 27480121 DOI: 10.1186/S13024-016-0117-0  0.337
2016 van Schaik IN, van Geloven N, Bril V, Hartung HP, Lewis RA, Sobue G, Lawo JP, Mielke O, Cornblath DR, Merkies IS. Subcutaneous immunoglobulin for maintenance treatment in chronic inflammatory demyelinating polyneuropathy (The PATH Study): study protocol for a randomized controlled trial. Trials. 17: 345. PMID 27455854 DOI: 10.1186/S13063-016-1466-2  0.312
2016 Lepka K, Berndt C, Hartung HP, Aktas O. Redox Events As Modulators of Pathology and Therapy of Neuroinflammatory Diseases. Frontiers in Cell and Developmental Biology. 4: 63. PMID 27446915 DOI: 10.3389/Fcell.2016.00063  0.352
2016 Ziemssen T, Gass A, Wuerfel J, Bayas A, Tackenberg B, Limmroth V, Linker R, Mäurer M, Haas J, Stangel M, Meergans M, Harlin O, Hartung HP. Design of TRUST, a non-interventional, multicenter, 3-year prospective study investigating an integrated patient management approach in patients with relapsing-remitting multiple sclerosis treated with natalizumab. Bmc Neurology. 16: 98. PMID 27405225 DOI: 10.1186/S12883-016-0625-0  0.304
2016 Kappos L, Li DK, Stüve O, Hartung HP, Freedman MS, Hemmer B, Rieckmann P, Montalban X, Ziemssen T, Hunter B, Arnould S, Wallström E, Selmaj K. Safety and Efficacy of Siponimod (BAF312) in Patients With Relapsing-Remitting Multiple Sclerosis: Dose-Blinded, Randomized Extension of the Phase 2 BOLD Study. Jama Neurology. PMID 27380540 DOI: 10.1001/Jamaneurol.2016.1451  0.306
2016 Leussink VI, Hartung HP, Kieseier BC, Stettner M. Subcutaneous immunoglobulins in the treatment of chronic immune-mediated neuropathies. Therapeutic Advances in Neurological Disorders. 9: 336-43. PMID 27366241 DOI: 10.1177/1756285616641583  0.354
2016 Szepanowski F, Derksen A, Steiner I, Meyer Zu Hörste G, Daldrup T, Hartung HP, Kieseier BC. Fingolimod promotes peripheral nerve regeneration via modulation of lysophospholipid signaling. Journal of Neuroinflammation. 13: 143. PMID 27283020 DOI: 10.1186/S12974-016-0612-9  0.314
2016 Buerth C, Mausberg AK, Heininger MK, Hartung HP, Kieseier BC, Ernst JF. Oral Tolerance Induction in Experimental Autoimmune Encephalomyelitis with Candida utilis Expressing the Immunogenic MOG35-55 Peptide. Plos One. 11: e0155082. PMID 27159446 DOI: 10.1371/Journal.Pone.0155082  0.359
2016 Cree BA, Hartung HP. Steering through complexity: management approaches in multiple sclerosis. Current Opinion in Neurology. PMID 27058222 DOI: 10.1097/Wco.0000000000000332  0.319
2016 Aktas O, Albrecht P, Hartung HP. Optic neuritis as a phase 2 paradigm for neuroprotection therapies of multiple sclerosis: update on current trials and perspectives. Current Opinion in Neurology. PMID 27035900 DOI: 10.1097/Wco.0000000000000327  0.352
2016 Jadasz JJ, Lubetzki C, Zalc B, Stankoff B, Hartung HP, Küry P. Recent achievements in stem cell-mediated myelin repair. Current Opinion in Neurology. PMID 27035898 DOI: 10.1097/Wco.0000000000000323  0.317
2016 Stankoff B, Jadasz JJ, Hartung HP, Küry P, Zalc B, Lubetzki C. Repair strategies for multiple sclerosis: challenges, achievements and perspectives. Current Opinion in Neurology. PMID 27035897 DOI: 10.1097/Wco.0000000000000325  0.359
2016 Leussink VI, Stettner M, Warnke C, Hartung HP. Fampridine-PR (prolonged released 4-aminopyridine) is not effective in patients with inflammatory demyelination of the peripheral nervous system. Journal of the Peripheral Nervous System : Jpns. PMID 26968589 DOI: 10.1111/Jns.12169  0.343
2016 Kremer D, Göttle P, Hartung HP, Küry P. Pushing Forward: Remyelination as the New Frontier in CNS Diseases. Trends in Neurosciences. PMID 26964504 DOI: 10.1016/J.Tins.2016.02.004  0.318
2016 Winkelmann A, Loebermann M, Reisinger EC, Hartung HP, Zettl UK. Disease-modifying therapies and infectious risks in multiple sclerosis. Nature Reviews. Neurology. PMID 26943779 DOI: 10.1038/Nrneurol.2016.21  0.34
2016 Stettner M, Hinrichs L, Guthoff R, Bairov S, Petropoulos IN, Warnke C, Hartung HP, Malik RA, Kieseier BC. Corneal confocal microscopy in chronic inflammatory demyelinating polyneuropathy. Annals of Clinical and Translational Neurology. 3: 88-100. PMID 26900579 DOI: 10.1002/Acn3.275  0.312
2016 Lublin F, Miller DH, Freedman MS, Cree BA, Wolinsky JS, Weiner H, Lubetzki C, Hartung HP, Montalban X, Uitdehaag BM, Merschhemke M, Li B, Putzki N, Liu FC, Häring DA, et al. Oral fingolimod in primary progressive multiple sclerosis (INFORMS): a phase 3, randomised, double-blind, placebo-controlled trial. Lancet (London, England). PMID 26827074 DOI: 10.1016/S0140-6736(15)01314-8  0.36
2016 Kremer D, Cui QL, Göttle P, Kuhlmann T, Hartung HP, Antel J, Küry P. CXCR7 Is Involved in Human Oligodendroglial Precursor Cell Maturation. Plos One. 11: e0146503. PMID 26741980 DOI: 10.1371/Journal.Pone.0146503  0.349
2016 Ingwersen J, Aktas O, Hartung HP. Advances in and Algorithms for the Treatment of Relapsing-Remitting Multiple Sclerosis. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 13: 47-57. PMID 26701666 DOI: 10.1007/S13311-015-0412-4  0.346
2016 Coles A, Arnold D, Barkhof F, Filippi M, Hartung H, Havrdova E, Selmaj K, Margolin D, Thangavelu K, Schippling S, Investigators CI. Alemtuzumab Persistently Slows Brain Volume Loss In Rrms Journal of Neurology, Neurosurgery, and Psychiatry. 87. DOI: 10.1136/Jnnp-2016-315106.125  0.308
2015 Warnke C, Olsson T, Hartung HP. PML: The Dark Side of Immunotherapy in Multiple Sclerosis. Trends in Pharmacological Sciences. 36: 799-801. PMID 26497099 DOI: 10.1016/J.Tips.2015.09.006  0.389
2015 Lill CM, Luessi F, Alcina A, Sokolova EA, Ugidos N, de la Hera B, Guillot-Noël L, Malhotra S, Reinthaler E, Schjeide BM, Mescheriakova JY, Mashychev A, Wohlers I, Akkad DA, Aktas O, ... ... Hartung HP, et al. Genome-wide significant association with seven novel multiple sclerosis risk loci. Journal of Medical Genetics. PMID 26475045 DOI: 10.1136/Jmedgenet-2015-103442  0.327
2015 Munger KL, Fitzgerald KC, Freedman MS, Hartung HP, Miller DH, Montalbán X, Edan G, Barkhof F, Suarez G, Radue EW, Sandbrink R, Kappos L, Pohl C, Ascherio A. No association of multiple sclerosis activity and progression with EBV or tobacco use in BENEFIT. Neurology. 85: 1694-701. PMID 26453645 DOI: 10.1212/Wnl.0000000000002099  0.355
2015 Ringelstein M, Albrecht P, Kleffner I, Bühn B, Harmel J, Müller AK, Finis D, Guthoff R, Bergholz R, Duning T, Krämer M, Paul F, Brandt A, Oberwahrenbrock T, Mikolajczak J, ... ... Hartung HP, et al. Retinal pathology in Susac syndrome detected by spectral-domain optical coherence tomography. Neurology. 85: 610-8. PMID 26203089 DOI: 10.1212/Wnl.0000000000001852  0.306
2015 Derfuss T, Curtin F, Guebelin C, Bridel C, Rasenack M, Matthey A, Du Pasquier R, Schluep M, Desmeules J, Lang AB, Perron H, Faucard R, Porchet H, Hartung HP, Kappos L, et al. A phase IIa randomized clinical study testing GNbAC1, a humanized monoclonal antibody against the envelope protein of multiple sclerosis associated endogenous retrovirus in multiple sclerosis patients - a twelve month follow-up. Journal of Neuroimmunology. 285: 68-70. PMID 26198921 DOI: 10.1016/J.Jneuroim.2015.05.019  0.375
2015 Tzekova N, Heinen A, Bunk S, Hermann C, Hartung HP, Reipert B, Küry P. Immunoglobulins stimulate cultured Schwann cell maturation and promote their potential to induce axonal outgrowth. Journal of Neuroinflammation. 12: 107. PMID 26022648 DOI: 10.1186/S12974-015-0331-7  0.335
2015 Bayry J, Hartung HP, Kaveri SV. IVIg for relapsing-remitting multiple sclerosis: promises and uncertainties. Trends in Pharmacological Sciences. 36: 419-21. PMID 26003802 DOI: 10.1016/J.Tips.2015.04.012  0.38
2015 Ringelstein M, Ayzenberg I, Harmel J, Lauenstein AS, Lensch E, Stögbauer F, Hellwig K, Ellrichmann G, Stettner M, Chan A, Hartung HP, Kieseier B, Gold R, Aktas O, Kleiter I. Long-term Therapy With Interleukin 6 Receptor Blockade in Highly Active Neuromyelitis Optica Spectrum Disorder. Jama Neurology. 72: 756-63. PMID 25985228 DOI: 10.1001/Jamaneurol.2015.0533  0.314
2015 Heinen A, Beyer F, Tzekova N, Hartung HP, Küry P. Fingolimod induces the transition to a nerve regeneration promoting Schwann cell phenotype. Experimental Neurology. 271: 25-35. PMID 25957629 DOI: 10.1016/J.Expneurol.2015.05.002  0.312
2015 Göttle P, Sabo JK, Heinen A, Venables G, Torres K, Tzekova N, Parras CM, Kremer D, Hartung HP, Cate HS, Küry P. Oligodendroglial maturation is dependent on intracellular protein shuttling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 906-19. PMID 25609610 DOI: 10.1523/Jneurosci.1423-14.2015  0.342
2015 Kremer D, Förster M, Schichel T, Göttle P, Hartung HP, Perron H, Küry P. The neutralizing antibody GNbAC1 abrogates HERV-W envelope protein-mediated oligodendroglial maturation blockade. Multiple Sclerosis (Houndmills, Basingstoke, England). 21: 1200-3. PMID 25480862 DOI: 10.1177/1352458514560926  0.333
2015 Warnke C, Stettner M, Lehmensiek V, Dehmel T, Mausberg AK, von Geldern G, Gold R, Kümpfel T, Hohlfeld R, Mäurer M, Stangel M, Straeten V, Limmroth V, Weber T, Kleinschnitz C, ... ... Hartung HP, et al. Natalizumab exerts a suppressive effect on surrogates of B cell function in blood and CSF. Multiple Sclerosis (Houndmills, Basingstoke, England). 21: 1036-44. PMID 25392339 DOI: 10.1177/1352458514556296  0.349
2015 Derfuss T, Curtin F, Guebelin C, Bridel C, Rasenack M, Matthey A, Du Pasquier R, Schluep M, Desmeules J, Lang AB, Perron H, Faucard R, Porchet H, Hartung HP, Kappos L, et al. A phase IIa randomised clinical study of GNbAC1, a humanised monoclonal antibody against the envelope protein of multiple sclerosis-associated endogenous retrovirus in multiple sclerosis patients. Multiple Sclerosis (Houndmills, Basingstoke, England). 21: 885-93. PMID 25392325 DOI: 10.1177/1352458514554052  0.382
2015 Kaufman M, Cree BA, De Sèze J, Fox RJ, Gold R, Hartung HP, Jeffery D, Kappos L, Montalbán X, Weinstock-Guttman B, Ticho B, Duda P, Pace A, Campagnolo D. Radiologic MS disease activity during natalizumab treatment interruption: findings from RESTORE. Journal of Neurology. 262: 326-36. PMID 25381458 DOI: 10.1007/S00415-014-7558-6  0.323
2015 Hartung HP, Aktas O, Boyko AN. Alemtuzumab: a new therapy for active relapsing-remitting multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 21: 22-34. PMID 25344374 DOI: 10.1177/1352458514549398  0.368
2015 Sharrack B, Mayer L, Coles A, Hartung H, Havrdova E, Selmaj K, Margolin D, Compston A. MANAGEMENT OF ADVERSE REACTIONS TO ALEMTUZUMAB INFUSION Journal of Neurology, Neurosurgery & Psychiatry. 86: e4.23-e4. DOI: 10.1136/Jnnp-2015-312379.119  0.333
2014 Harmel J, Ringelstein M, Ingwersen J, Mathys C, Goebels N, Hartung HP, Jarius S, Aktas O. Interferon-β-related tumefactive brain lesion in a Caucasian patient with neuromyelitis optica and clinical stabilization with tocilizumab. Bmc Neurology. 14: 247. PMID 25516429 DOI: 10.1186/S12883-014-0247-3  0.392
2014 Meyer zu Hörste G, Cordes S, Mausberg AK, Zozulya AL, Wessig C, Sparwasser T, Mathys C, Wiendl H, Hartung HP, Kieseier BC. FoxP3+ regulatory T cells determine disease severity in rodent models of inflammatory neuropathies. Plos One. 9: e108756. PMID 25286182 DOI: 10.1371/Journal.Pone.0108756  0.37
2014 Meyer zu Horste G, Mausberg AK, Cordes S, El-Haddad H, Partke HJ, Leussink VI, Roden M, Martin S, Steinman L, Hartung HP, Kieseier BC. Thymic epithelium determines a spontaneous chronic neuritis in Icam1(tm1Jcgr)NOD mice. Journal of Immunology (Baltimore, Md. : 1950). 193: 2678-90. PMID 25108020 DOI: 10.4049/Jimmunol.1400367  0.313
2014 Ritter C, Förster D, Albrecht P, Hartung HP, Kieseier BC, Lehmann HC. IVIG regulates BAFF expression in patients with chronic inflammatory demyelinating polyneuropathy (CIDP). Journal of Neuroimmunology. 274: 225-9. PMID 25002077 DOI: 10.1016/J.Jneuroim.2014.06.007  0.338
2014 Warnke C, von Geldern G, Markwerth P, Dehmel T, Hoepner R, Gold R, Pawlita M, Kümpfel T, Mäurer M, Stangel M, Wegner F, Hohlfeld R, Straeten V, Limmroth V, Weber T, ... ... Hartung HP, et al. Cerebrospinal fluid JC virus antibody index for diagnosis of natalizumab-associated progressive multifocal leukoencephalopathy. Annals of Neurology. 76: 792-801. PMID 24729444 DOI: 10.1002/Ana.24153  0.303
2014 Fox RJ, Cree BA, De Sèze J, Gold R, Hartung HP, Jeffery D, Kappos L, Kaufman M, Montalbán X, Weinstock-Guttman B, Anderson B, Natarajan A, Ticho B, Duda P. MS disease activity in RESTORE: a randomized 24-week natalizumab treatment interruption study. Neurology. 82: 1491-8. PMID 24682966 DOI: 10.1212/Wnl.0000000000000355  0.357
2014 Kappos L, Hartung HP, Freedman MS, Boyko A, Radü EW, Mikol DD, Lamarine M, Hyvert Y, Freudensprung U, Plitz T, van Beek J. Atacicept in multiple sclerosis (ATAMS): a randomised, placebo-controlled, double-blind, phase 2 trial. The Lancet. Neurology. 13: 353-63. PMID 24613349 DOI: 10.1016/S1474-4422(14)70028-6  0.338
2014 Hartung HP, Aktas O, Menge T, Kieseier BC. Immune regulation of multiple sclerosis. Handbook of Clinical Neurology. 122: 3-14. PMID 24507511 DOI: 10.1016/B978-0-444-52001-2.00001-7  0.405
2014 Ascherio A, Munger KL, White R, Köchert K, Simon KC, Polman CH, Freedman MS, Hartung HP, Miller DH, Montalbán X, Edan G, Barkhof F, Pleimes D, Radü EW, Sandbrink R, et al. Vitamin D as an early predictor of multiple sclerosis activity and progression. Jama Neurology. 71: 306-14. PMID 24445558 DOI: 10.1001/Jamaneurol.2013.5993  0.342
2014 Curtin F, Hartung HP. Novel therapeutic options for multiple sclerosis. Expert Review of Clinical Pharmacology. 7: 91-104. PMID 24325127 DOI: 10.1586/17512433.2014.865517  0.384
2014 Nagtegaal GJ, Pohl C, Wattjes MP, Hulst HE, Freedman MS, Hartung HP, Miller D, Montalban X, Kappos L, Edan G, Pleimes D, Beckman K, Stemper B, Polman CH, Sandbrink R, et al. Interferon beta-1b reduces black holes in a randomised trial of clinically isolated syndrome. Multiple Sclerosis (Houndmills, Basingstoke, England). 20: 234-42. PMID 23842212 DOI: 10.1177/1352458513494491  0.343
2014 Dehmel T, Warnke C, Ramanujam R, Wolffram K, Leussink VI, Hartung H, Kieseier BC. Correlation of fingolimod induced lymphopenia and physical measures in MS patients Journal of Neuroimmunology. 275: 216-217. DOI: 10.1016/J.Jneuroim.2014.08.581  0.312
2014 Malviya M, Melzer N, Widman G, Elger C, Wiendl H, Hartung H, Goebels N. Autoimmune encephalitis: Single cell PCR analysis of the intrathecal plasma cell repertoire Journal of Neuroimmunology. 275: 5. DOI: 10.1016/J.Jneuroim.2014.08.019  0.312
2013 Warnke C, Mausberg AK, Stettner M, Dehmel T, Nekrich L, Meyer zu Horste G, Hartung HP, Fogdell-Hahn A, Adams O, Kieseier BC. Natalizumab affects the T-cell receptor repertoire in patients with multiple sclerosis. Neurology. 81: 1400-8. PMID 24049136 DOI: 10.1212/Wnl.0B013E3182A84101  0.394
2013 Lehmann HC, Hughes RA, Hartung HP. Treatment of chronic inflammatory demyelinating polyradiculoneuropathy. Handbook of Clinical Neurology. 115: 415-27. PMID 23931793 DOI: 10.1016/B978-0-444-52902-2.00023-0  0.357
2013 Pfeifenbring S, Metz I, Kremer D, Küry P, Hartung HP, Brück W. Oligodendroglial lineage cells express nuclear p57kip2 in multiple sclerosis lesions. Glia. 61: 1250-60. PMID 23828667 DOI: 10.1002/Glia.22512  0.363
2013 Warnke C, Kieseier BC, Hartung HP. Biotherapeutics for the treatment of multiple sclerosis: hopes and hazards. Journal of Neural Transmission (Vienna, Austria : 1996). 120: S55-60. PMID 23793997 DOI: 10.1007/S00702-013-1055-4  0.375
2013 Buttmann M, Kaveri S, Hartung HP. Polyclonal immunoglobulin G for autoimmune demyelinating nervous system disorders. Trends in Pharmacological Sciences. 34: 445-57. PMID 23791035 DOI: 10.1016/J.Tips.2013.05.009  0.393
2013 Stettner M, Wolffram K, Mausberg AK, Albrecht P, Derksen A, Methner A, Dehmel T, Hartung HP, Dietrich H, Kieseier BC. Promoting myelination in an in vitro mouse model of the peripheral nervous system: the effect of wine ingredients [corrected]. Plos One. 8: e66079. PMID 23762469 DOI: 10.1371/Journal.Pone.0066079  0.308
2013 Warnke C, Pawlita M, Dehmel T, Posevitz-Fejfar A, Hartung HP, Wiendl H, Kieseier BC, Adams O. An assay to quantify species-specific anti-JC virus antibody levels in MS patients. Multiple Sclerosis (Houndmills, Basingstoke, England). 19: 1137-44. PMID 23388163 DOI: 10.1177/1352458513475489  0.305
2013 Jantzen SU, Ferrea S, Wach C, Quasthoff K, Illes S, Scherfeld D, Hartung HP, Seitz RJ, Dihné M. In vitro neuronal network activity in NMDA receptor encephalitis. Bmc Neuroscience. 14: 17. PMID 23379293 DOI: 10.1186/1471-2202-14-17  0.5
2013 Lill CM, Schjeide BM, Graetz C, Liu T, Damotte V, Akkad DA, Blaschke P, Gerdes LA, Kroner A, Luessi F, Cournu-Rebeix I, Hoffjan S, Winkelmann A, Touze E, Pico F, ... ... Hartung HP, et al. Genome-wide significant association of ANKRD55 rs6859219 and multiple sclerosis risk. Journal of Medical Genetics. 50: 140-3. PMID 23315543 DOI: 10.1136/Jmedgenet-2012-101411  0.332
2013 Comi G, Hartung HP, Kurukulasuriya NC, Greenberg SJ, Scaramozza M. Cladribine tablets for the treatment of relapsing-remitting multiple sclerosis. Expert Opinion On Pharmacotherapy. 14: 123-36. PMID 23256518 DOI: 10.1517/14656566.2013.754012  0.395
2013 Lee JI, Macht S, Albrecht P, Hartung HP, Goebels N. Brachial amyotrophic diparesis associated with anti-Hu positive anterior horn cell disease and autonomic disorder. Journal of Neurology. 260: 301-2. PMID 23135291 DOI: 10.1007/S00415-012-6711-3  0.319
2012 Lehmann HC, Hughes RA, Kieseier BC, Hartung HP. Recent developments and future directions in Guillain-Barré syndrome. Journal of the Peripheral Nervous System : Jpns. 17: 57-70. PMID 23279434 DOI: 10.1111/J.1529-8027.2012.00433.X  0.325
2012 Curtin F, Lang AB, Perron H, Laumonier M, Vidal V, Porchet HC, Hartung HP. GNbAC1, a humanized monoclonal antibody against the envelope protein of multiple sclerosis-associated endogenous retrovirus: a first-in-humans randomized clinical study. Clinical Therapeutics. 34: 2268-78. PMID 23200102 DOI: 10.1016/J.Clinthera.2012.11.006  0.319
2012 Jander S, Turowski B, Kieseier BC, Hartung H. Emerging tumefactive multiple sclerosis after switching therapy from natalizumab to fingolimod. Multiple Sclerosis Journal. 18: 1650-1652. PMID 23100527 DOI: 10.1177/1352458512463768  0.326
2012 Mentzer D, Prestel J, Adams O, Gold R, Hartung HP, Hengel H, Kieseier BC, Ludwig WD, Keller-Stanislawski B. Case definition for progressive multifocal leukoencephalopathy following treatment with monoclonal antibodies. Journal of Neurology, Neurosurgery, and Psychiatry. 83: 927-33. PMID 22807558 DOI: 10.1136/Jnnp-2012-302478  0.31
2012 Köhne A, Stettner M, Jangouk P, Dehmel T, Hartung HP, Lehmann HC, Kieseier BC. Fingolimod impedes Schwann cell-mediated myelination: implications for the treatment of immune neuropathies? Archives of Neurology. 69: 1280-9. PMID 22751954 DOI: 10.1001/Archneurol.2012.394  0.364
2012 Warnke C, Dehmel T, Posevitz-Fejfár A, Chan A, Berthele A, Schmidt S, Haas J, Kronsbein HC, Seitz F, Tackenberg B, Mäurer M, Gerbershagen K, Limmroth V, Adams O, Hartung HP, et al. Anti-JC-virus antibody prevalence in a German MS cohort. Multiple Sclerosis (Houndmills, Basingstoke, England). 18: 1054-5. PMID 22740609 DOI: 10.1177/1352458511429955  0.302
2012 Caloyeras JP, Zhang B, Wang C, Eriksson M, Fredrikson S, Beckmann K, Knappertz V, Pohl C, Hartung HP, Shah D, Miller JD, Sandbrink R, Lanius V, Gondek K, Russell MW. Cost-effectiveness analysis of interferon beta-1b for the treatment of patients with a first clinical event suggestive of multiple sclerosis. Clinical Therapeutics. 34: 1132-44. PMID 22541587 DOI: 10.1016/J.Clinthera.2012.03.004  0.345
2012 Penner IK, Stemper B, Calabrese P, Freedman MS, Polman CH, Edan G, Hartung HP, Miller DH, Montalbán X, Barkhof F, Pleimes D, Lanius V, Pohl C, Kappos L, Sandbrink R. Effects of interferon beta-1b on cognitive performance in patients with a first event suggestive of multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 18: 1466-71. PMID 22492127 DOI: 10.1177/1352458512442438  0.31
2012 Husseini L, Saleh A, Reifenberger G, Hartung HP, Kieseier BC. Inflammatory demyelinating brain lesions heralding primary CNS lymphoma. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 39: 6-10. PMID 22384490 DOI: 10.1017/S0317167100012610  0.311
2012 Kleiter I, Hellwig K, Berthele A, Kümpfel T, Linker RA, Hartung HP, Paul F, Aktas O. Failure of natalizumab to prevent relapses in neuromyelitis optica Archives of Neurology. 69: 239-245. PMID 22332191 DOI: 10.1001/Archneurol.2011.216  0.367
2012 Rieckmann P, Heidenreich F, Sailer M, Zettl UK, Zessack N, Hartung HP, Gold R. Treatment de-escalation after mitoxantrone therapy: results of a phase IV, multicentre, open-label, randomized study of subcutaneous interferon beta-1a in patients with relapsing multiple sclerosis. Therapeutic Advances in Neurological Disorders. 5: 3-12. PMID 22276072 DOI: 10.1177/1756285611428503  0.344
2012 Loebermann M, Winkelmann A, Hartung HP, Hengel H, Reisinger EC, Zettl UK. Vaccination against infection in patients with multiple sclerosis Nature Reviews Neurology. 8: 143-151. PMID 22270022 DOI: 10.1038/Nrneurol.2012.8  0.328
2012 Lill CM, Schjeide BM, Akkad DA, Blaschke P, Winkelmann A, Gerdes LA, Hoffjan S, Luessi F, Dörner T, Li SC, Steinhagen-Thiessen E, Lindenberger U, Chan A, Hartung HP, Aktas O, et al. Independent replication of STAT3 association with multiple sclerosis risk in a large German case-control sample. Neurogenetics. 13: 83-6. PMID 22095036 DOI: 10.1007/S10048-011-0305-6  0.312
2012 Warnke C, Leussink VI, Goebels N, Aktas O, Boyko A, Kieseier BC, Hartung HP. Cladribine as a therapeutic option in multiple sclerosis Clinical Immunology. 142: 68-75. PMID 21733757 DOI: 10.1016/J.Clim.2011.05.009  0.325
2012 Ingwersen J, Aktas O, Kuery P, Kieseier B, Boyko A, Hartung HP. Fingolimod in multiple sclerosis: Mechanisms of action and clinical efficacy Clinical Immunology. 142: 15-24. PMID 21669553 DOI: 10.1016/J.Clim.2011.05.005  0.382
2012 Bril V, Cornblath DR, Hartung H, Lewis RA, Merkies IS, Zenker O, Bexon M, Schaik INv. PATH (polyneuropathy and treatment with Hizentra ®: a randomized, controlled trial of Hizentra ®, a 20% immunoglobulin preparation for subcutaneous administration, in patients with chronic inflammatory demyelinating polyradiculoneuropathy F1000research. 3. DOI: 10.7490/F1000Research.1090020.1  0.315
2012 Brandt AU, Zimmermann H, Kaufhold F, Promesberger J, Schippling S, Finis D, Aktas O, Geis C, Ringelstein M, Ringelstein EB, Hartung HP, Paul F, Kleffner I, Dörr J. Patterns of retinal damage facilitate differential diagnosis between Susac syndrome and MS Plos One. 7. DOI: 10.1371/Journal.Pone.0038741  0.338
2011 Hecker M, Paap BK, Goertsches RH, Kandulski O, Fatum C, Koczan D, Hartung HP, Thiesen HJ, Zettl UK. Reassessment of blood gene expression markers for the prognosis of relapsing-remitting multiple sclerosis. Plos One. 6: e29648. PMID 22216338 DOI: 10.1371/Journal.Pone.0029648  0.334
2011 Dihné M, Hartung HP, Seitz RJ. Restoring neuronal function after stroke by cell replacement: anatomic and functional considerations. Stroke; a Journal of Cerebral Circulation. 42: 2342-50. PMID 21737804 DOI: 10.1161/Strokeaha.111.613422  0.47
2011 Hartung HP, Lehmann HC, Kieseier BC, Hughes RA. Novel treatment for immune neuropathies on the horizon. Journal of the Peripheral Nervous System : Jpns. 16: 75-83. PMID 21692904 DOI: 10.1111/J.1529-8027.2011.00334.X  0.36
2011 Kremer D, Aktas O, Hartung HP, Küry P. The complex world of oligodendroglial differentiation inhibitors Annals of Neurology. 69: 602-618. PMID 21520230 DOI: 10.1002/Ana.22415  0.383
2011 Kotter MR, Stadelmann C, Hartung HP. Enhancing remyelination in disease--can we wrap it up? Brain : a Journal of Neurology. 134: 1882-900. PMID 21507994 DOI: 10.1093/Brain/Awr014  0.37
2011 Matzke B, Metze C, Winkelmann A, Grossmann A, Hartung HP, Benecke R, Zettl UK. Severe relapse of multiple sclerosis during plasma exchange treatment. Multiple Sclerosis (Houndmills, Basingstoke, England). 17: 759-62. PMID 21427132 DOI: 10.1177/1352458511401461  0.315
2011 Hartung HP, Aktas O. Evolution of multiple sclerosis treatment: Next generation therapies meet next generation efficacy criteria The Lancet Neurology. 10: 293-295. PMID 21397566 DOI: 10.1016/S1474-4422(11)70043-6  0.315
2011 Hartung H, Montalban X, Sorensen PS, Vermersch P, Olsson T. Principles of a new treatment algorithm in multiple sclerosis. Expert Review of Neurotherapeutics. 11: 351-362. PMID 21375441 DOI: 10.1586/Ern.11.15  0.355
2011 Menge T, Hartung HP, Kieseier BC. Neutralizing antibodies in interferon beta treated patients with multiple sclerosis: knowing what to do now : Commentary to: 10.1007/s00415-010-5844-5 "One-year evaluation of factors affecting the biological activity of interferon beta in multiple sclerosis patients" by S. Malucchi et al. Journal of Neurology. 258: 904-7. PMID 21340521 DOI: 10.1007/S00415-011-5941-0  0.394
2011 Lehmann HC, Hartung HP. Plasma exchange and intravenous immunoglobulins: mechanism of action in immune-mediated neuropathies. Journal of Neuroimmunology. 231: 61-9. PMID 21056913 DOI: 10.1016/J.Jneuroim.2010.09.015  0.35
2011 Aktas O, Hartung H. Oral therapies for multiple sclerosis: fingolimod and cladribine Hot Topics in Neurology and Psychiatry. DOI: 10.4147/Htn-100929  0.316
2010 Hartung H, Kieseier BC. Atacicept: targeting B cells in multiple sclerosis. Therapeutic Advances in Neurological Disorders. 3: 205-216. PMID 21179612 DOI: 10.1177/1756285610371146  0.352
2010 Warnke C, Smolianov V, Dehmel T, Andrée M, Hengel H, Zohren F, Arendt G, Wiendl H, Haas R, Hartung HP, Adams O, Kieseier BC. CD34+ progenitor cells mobilized by natalizumab are not a relevant reservoir for JC virus. Multiple Sclerosis (Houndmills, Basingstoke, England). 17: 151-6. PMID 21078695 DOI: 10.1177/1352458510385834  0.338
2010 Sominanda A, Lundkvist M, Fogdell-Hahn A, Hemmer B, Hartung HP, Hillert J, Menge T, Kieseier BC. Inhibition of endogenous interferon beta by neutralizing antibodies against recombinant interferon beta. Archives of Neurology. 67: 1095-101. PMID 20837854 DOI: 10.1001/Archneurol.2010.218  0.306
2010 Donofrio PD, Bril V, Dalakas MC, Deng C, Hanna K, Hartung HP, Hughes R, Latov N, Merkies I, van Doorn P. Safety and tolerability of immune globulin intravenous in chronic inflammatory demyelinating polyradiculoneuropathy. Archives of Neurology. 67: 1082-8. PMID 20837852 DOI: 10.1001/Archneurol.2010.223  0.326
2010 Warnke C, Menge T, Hartung HP, Racke MK, Cravens PD, Bennett JL, Frohman EM, Greenberg BM, Zamvil SS, Gold R, Hemmer B, Kieseier BC, Stüve O. Natalizumab and progressive multifocal leukoencephalopathy: what are the causal factors and can it be avoided? Archives of Neurology. 67: 923-30. PMID 20697042 DOI: 10.1001/Archneurol.2010.161  0.389
2010 Wolf C, Menge T, Stenner MP, Meyer zu Hörste G, Saleh A, Hartung HP, Wiendl H, Kieseier BC. Natalizumab treatment in a patient with chronic inflammatory demyelinating polyneuropathy. Archives of Neurology. 67: 881-3. PMID 20625098 DOI: 10.1001/Archneurol.2010.143  0.358
2010 Mix E, Meyer-Rienecker H, Hartung H, Zettl UK. Animal models of multiple sclerosis--potentials and limitations. Progress in Neurobiology. 92: 386-404. PMID 20558237 DOI: 10.1016/J.Pneurobio.2010.06.005  0.382
2010 Aktas O, Küry P, Kieseier B, Hartung HP. Fingolimod is a potential novel therapy for multiple sclerosis Nature Reviews Neurology. 6: 373-382. PMID 20551946 DOI: 10.1038/Nrneurol.2010.76  0.358
2010 Latov N, Deng C, Dalakas MC, Bril V, Donofrio P, Hanna K, Hartung HP, Hughes RA, Merkies IS, van Doorn PA. Timing and course of clinical response to intravenous immunoglobulin in chronic inflammatory demyelinating polyradiculoneuropathy. Archives of Neurology. 67: 802-7. PMID 20457948 DOI: 10.1001/Archneurol.2010.105  0.3
2010 Hartung HP, Aktas O. Oral therapies for multiple sclerosis: are we there yet? The Lancet Neurology. 9: 454-457. PMID 20398852 DOI: 10.1016/S1474-4422(10)70088-0  0.314
2010 Aktas O, Kieseier B, Hartung HP. Neuroprotection, regeneration and immunomodulation: broadening the therapeutic repertoire in multiple sclerosis. Trends in Neurosciences. 33: 140-52. PMID 20045200 DOI: 10.1016/J.Tins.2009.12.002  0.402
2010 Aktas O, Hartung HP. Neuromyelitis and more: the unfolding spectrum of aquaporin 4-related neurological diseases. Journal of Neurology. 256: 1906-8. PMID 19768482 DOI: 10.1007/S00415-009-5317-X  0.407
2010 Meyer Zu Horste G, Heidenreich H, Lehmann HC, Ferrone S, Hartung HP, Wiendl H, Kieseier BC. Expression of antigen processing and presenting molecules by Schwann cells in inflammatory neuropathies. Glia. 58: 80-92. PMID 19544394 DOI: 10.1002/Glia.20903  0.32
2009 Lehmann HC, Meyer Zu Horste G, Kieseier BC, Hartung HP. Pathogenesis and treatment of immune-mediated neuropathies. Therapeutic Advances in Neurological Disorders. 2: 261-81. PMID 21179533 DOI: 10.1177/1756285609104792  0.327
2009 Hartung HP, Aktas O. Bleak prospects for primary progressive multiple sclerosis therapy: downs and downs, but a glimmer of hope. Annals of Neurology. 66: 429-32. PMID 19847907 DOI: 10.1002/Ana.21880  0.323
2009 Kappos L, Freedman MS, Polman CH, Edan G, Hartung HP, Miller DH, Montalbán X, Barkhof F, Radü EW, Metzig C, Bauer L, Lanius V, Sandbrink R, Pohl C. Long-term effect of early treatment with interferon beta-1b after a first clinical event suggestive of multiple sclerosis: 5-year active treatment extension of the phase 3 BENEFIT trial. The Lancet. Neurology. 8: 987-97. PMID 19748319 DOI: 10.1016/S1474-4422(09)70237-6  0.333
2009 Cepok S, Schreiber H, Hoffmann S, Zhou D, Neuhaus O, von Geldern G, Hochgesand S, Nessler S, Rothhammer V, Lang M, Hartung HP, Hemmer B. Enhancement of chemokine expression by interferon beta therapy in patients with multiple sclerosis. Archives of Neurology. 66: 1216-23. PMID 19667211 DOI: 10.1001/Archneurol.2009.138  0.327
2009 Lehmann HC, Hartung HP. Variants of Guillain-Barré syndrome: low incidence but high impact. Journal of Neurology. 256: 1909-10. PMID 19633905 DOI: 10.1007/S00415-009-5253-9  0.323
2009 Tumani H, Hartung HP, Hemmer B, Teunissen C, Deisenhammer F, Giovannoni G, Zettl UK. Cerebrospinal fluid biomarkers in multiple sclerosis. Neurobiology of Disease. 35: 117-27. PMID 19426803 DOI: 10.1016/J.Nbd.2009.04.010  0.354
2009 Hartung HP. High-dose, high-frequency recombinant interferon beta-1a in the treatment of multiple sclerosis. Expert Opinion On Pharmacotherapy. 10: 291-309. PMID 19236200 DOI: 10.1517/14656560802677882  0.357
2009 Stüve O, Leussink VI, Fröhlich R, Hemmer B, Hartung HP, Menge T, Kieseier BC. Long-term B-lymphocyte depletion with rituximab in patients with relapsing-remitting multiple sclerosis. Archives of Neurology. 66: 259-61. PMID 19204165 DOI: 10.1001/Archneurol.2008.551  0.332
2009 Wellen J, Walter J, Jangouk P, Hartung HP, Dihné M. Neural precursor cells as a novel target for interferon-beta. Neuropharmacology. 56: 386-98. PMID 18930745 DOI: 10.1016/J.Neuropharm.2008.09.011  0.312
2009 Vollmar P, Nessler S, Kalluri SR, Hartung HP, Hemmer B. The antidepressant venlafaxine ameliorates murine experimental autoimmune encephalomyelitis by suppression of pro-inflammatory cytokines. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 12: 525-36. PMID 18922202 DOI: 10.1017/S1461145708009425  0.352
2009 Hartung H. New oral therapies may offer improved treatment options for patients with multiple sclerosis Current Opinion in Neurology. 22: S10-S14. DOI: 10.1097/01.Wco.0000347402.08903.87  0.359
2008 König FB, Wildemann B, Nessler S, Zhou D, Hemmer B, Metz I, Hartung HP, Kieseier BC, Brück W. Persistence of immunopathological and radiological traits in multiple sclerosis. Archives of Neurology. 65: 1527-32. PMID 19001173 DOI: 10.1001/Archneur.65.11.1527  0.387
2008 Kieseier BC, Meyer Zu Hörste G, Lehmann HC, Gold R, Hartung HP. Intravenous immunoglobulins in the treatment of immune neuropathies. Current Opinion in Neurology. 21: 555-62. PMID 18769249 DOI: 10.1097/Wco.0B013E32830Efc03  0.31
2008 Hartung HP, Kieseier BC. Advances in biotechnology and novel insights into pathophysiology have contributed to an increased understanding of the pathomechanisms of diseases affecting the peripheral nervous system. Current Opinion in Neurology. 21: 517-8. PMID 18769243 DOI: 10.1097/Wco.0B013E32830F1E61  0.301
2008 Jörgens S, Biermann-Ruben K, Kurz MW, Flügel C, Daehli Kurz K, Antke C, Hartung HP, Seitz RJ, Schnitzler A. Word deafness as a cortical auditory processing deficit: a case report with MEG. Neurocase. 14: 307-16. PMID 18766983 DOI: 10.1080/13554790802363738  0.475
2008 Hartung H. Advances in the understanding of the mechanism of action of IVIg. Journal of Neurology. 255: 3-6. PMID 18685919 DOI: 10.1007/S00415-008-3002-0  0.33
2008 Killestein J, Hartung HP. Interferon beta in multiple sclerosis: predicting response at an early stage. Journal of Neurology, Neurosurgery, and Psychiatry. 79: 616-7. PMID 18487553 DOI: 10.1136/Jnnp.2007.138396  0.391
2008 Zohren F, Toutzaris D, Klärner V, Hartung H, Kieseier B, Haas R. The monoclonal anti-VLA-4 antibody natalizumab mobilizes CD34 hematopoietic progenitor cells in humans Blood. 111: 3893-3895. PMID 18235044 DOI: 10.1182/Blood-2007-10-120329  0.316
2008 Polman C, Kappos L, Freedman MS, Edan G, Hartung HP, Miller DH, Montalbán X, Barkhof F, Selmaj K, Uitdehaag BM, Dahms S, Bauer L, Pohl C, Sandbrink R. Subgroups of the BENEFIT study: risk of developing MS and treatment effect of interferon beta-1b. Journal of Neurology. 255: 480-7. PMID 18004635 DOI: 10.1007/S00415-007-0733-2  0.342
2008 Neuhaus O, Kieseier BC, Hartung HP. Immunosuppressive agents in multiple sclerosis. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 4: 654-60. PMID 17920546 DOI: 10.1016/J.Nurt.2007.08.003  0.364
2008 Meyer zu Hörste G, Hu W, Hartung HP, Lehmann HC, Kieseier BC. The immunocompetence of Schwann cells. Muscle & Nerve. 37: 3-13. PMID 17823955 DOI: 10.1002/Mus.20893  0.356
2007 Albrecht P, Fröhlich R, Hartung HP, Kieseier BC, Methner A. Optical coherence tomography measures axonal loss in multiple sclerosis independently of optic neuritis. Journal of Neurology. 254: 1595-6. PMID 17987252 DOI: 10.1007/S00415-007-0538-3  0.365
2007 Hemmer B, Hartung HP. Toward the development of rational therapies in multiple sclerosis: what is on the horizon? Annals of Neurology. 62: 314-26. PMID 17969020 DOI: 10.1002/Ana.21289  0.393
2007 Barkhof F, Polman CH, Radue EW, Kappos L, Freedman MS, Edan G, Hartung HP, Miller DH, Montalbán X, Poppe P, de Vos M, Lasri F, Bauer L, Dahms S, Wagner K, et al. Magnetic resonance imaging effects of interferon beta-1b in the BENEFIT study: integrated 2-year results. Archives of Neurology. 64: 1292-8. PMID 17846268 DOI: 10.1001/Archneur.64.9.1292  0.311
2007 Kappos L, Freedman MS, Polman CH, Edan G, Hartung HP, Miller DH, Montalbán X, Barkhof F, Radü EW, Bauer L, Dahms S, Lanius V, Pohl C, Sandbrink R. Effect of early versus delayed interferon beta-1b treatment on disability after a first clinical event suggestive of multiple sclerosis: a 3-year follow-up analysis of the BENEFIT study. Lancet (London, England). 370: 389-97. PMID 17679016 DOI: 10.1016/S0140-6736(07)61194-5  0.35
2007 Nessler S, Boretius S, Stadelmann C, Bittner A, Merkler D, Hartung HP, Michaelis T, Brück W, Frahm J, Sommer N, Hemmer B. Early MRI changes in a mouse model of multiple sclerosis are predictive of severe inflammatory tissue damage. Brain : a Journal of Neurology. 130: 2186-98. PMID 17617655 DOI: 10.1093/Brain/Awm105  0.305
2007 Kieseier BC, Wiendl H, Hemmer B, Hartung HP. Treatment and treatment trials in multiple sclerosis. Current Opinion in Neurology. 20: 286-93. PMID 17495622 DOI: 10.1097/Wco.0B013E3281568B80  0.323
2007 Neuhaus O, Hartung HP. Evaluation of atorvastatin and simvastatin for treatment of multiple sclerosis. Expert Review of Neurotherapeutics. 7: 547-56. PMID 17492904 DOI: 10.1586/14737175.7.5.547  0.39
2007 Hartung H, Polman C, Bertolotto A, Deisenhammer F, Giovannoni G, Havrdova E, Hemmer B, Hillert J, Kappos L, Kieseier B, Killestein J, Malcus C, Comabella M, Pachner A, Schellekens H, et al. Neutralising antibodies to interferon β in multiple sclerosis Journal of Neurology. 254: 827-837. PMID 17457510 DOI: 10.1007/S00415-006-0486-3  0.345
2007 Wiendl H, Kieseier BC, Weissert R, Mylius HA, Pichlmeier U, Hartung H, Melms A, Kuker W, Weller M. Treatment of active secondary progressivemultiple sclerosis with treosulfan Journal of Neurology. 254: 884-889. PMID 17446994 DOI: 10.1007/S00415-006-0459-6  0.385
2007 Lehmann HC, Köhne A, Meyer zu Hörste G, Dehmel T, Kiehl O, Hartung HP, Kastenbauer S, Kieseier BC. Role of nitric oxide as mediator of nerve injury in inflammatory neuropathies. Journal of Neuropathology and Experimental Neurology. 66: 305-12. PMID 17413321 DOI: 10.1097/Nen.0B013E3180408Daa  0.322
2007 Meyer zu Hörste G, Hartung HP, Kieseier BC. From bench to bedside--experimental rationale for immune-specific therapies in the inflamed peripheral nerve. Nature Clinical Practice. Neurology. 3: 198-211. PMID 17410107 DOI: 10.1038/Ncpneuro0452  0.37
2007 Neuhaus O, Kieseier BC, Hartung HP. Pharmacokinetics and pharmacodynamics of the interferon-betas, glatiramer acetate, and mitoxantrone in multiple sclerosis. Journal of the Neurological Sciences. 259: 27-37. PMID 17391705 DOI: 10.1016/J.Jns.2006.05.071  0.345
2007 Kuhle J, Pohl C, Mehling M, Edan G, Freedman MS, Hartung HP, Polman CH, Miller DH, Montalban X, Barkhof F, Bauer L, Dahms S, Lindberg R, Kappos L, Sandbrink R. Lack of association between antimyelin antibodies and progression to multiple sclerosis. The New England Journal of Medicine. 356: 371-8. PMID 17251533 DOI: 10.1056/Nejmoa063602  0.389
2007 Dehmel T, Janke A, Hartung HP, Goebel HH, Wiendl H, Kieseier BC. The cell-specific expression of metalloproteinase-disintegrins (ADAMs) in inflammatory myopathies. Neurobiology of Disease. 25: 665-74. PMID 17207628 DOI: 10.1016/J.Nbd.2006.11.008  0.301
2007 Hemmer B, Nessler S, Zhou D, Kieseier B, Hartung HP. Immunopathogenesis and immunotherapy of multiple sclerosis. Nature Clinical Practice. Neurology. 2: 201-11. PMID 16932551 DOI: 10.1038/Ncpneuro0154  0.405
2007 Zohren F, Czibere A, Toutzaris D, Hartung H, Bruns I, Haas R. Treatment with Natalizumab in Patients with Multiple Sclerosis Is Associated with Increased Numbers of Circulating CD34+ Cells in the Peripheral Blood. Blood. 110: 4916-4916. DOI: 10.1182/Blood.V110.11.4916.4916  0.302
2007 Kappos L, Montalban X, Hartung H, Freedman M, Polman C. Treating clinically isolated syndromes suggestive of MS – Authors' reply The Lancet. 370: 2000-2001. DOI: 10.1016/S0140-6736(07)61855-8  0.321
2007 Hemmer B, Töpfner N, Hartung H. 18 – Immunopathogenesis of Multiple Sclerosis Neurobiology of Disease. 197-204. DOI: 10.1016/B978-012088592-3/50020-7  0.422
2006 Zhou D, Srivastava R, Nessler S, Grummel V, Sommer N, Brück W, Hartung HP, Stadelmann C, Hemmer B. Identification of a pathogenic antibody response to native myelin oligodendrocyte glycoprotein in multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 103: 19057-62. PMID 17142321 DOI: 10.1073/Pnas.0607242103  0.396
2006 Kieseier BC, Hartung HP. Polyneuropathy associated with interferon beta treatment in patients with multiple sclerosis. Neurology. 66: 955; author reply 95. PMID 16567732 DOI: 10.1212/01.Wnl.0000218668.17791.Cf  0.335
2006 Hartung HP, Kieseier BC, Hemmer B. Purely systemically active anti-inflammatory treatments are adequate to control multiple sclerosis. Journal of Neurology. v30-7. PMID 16254700 DOI: 10.1007/S00415-005-5006-3  0.392
2006 Kurz M, Pischel H, Hartung HP, Kieseier BC. Tumor necrosis factor-alpha-converting enzyme is expressed in the inflamed peripheral nervous system. Journal of the Peripheral Nervous System : Jpns. 10: 311-8. PMID 16221290 DOI: 10.1111/J.1085-9489.2005.10309.X  0.322
2006 Neuhaus O, Kieseier BC, Hartung HP. Therapeutic role of mitoxantrone in multiple sclerosis. Pharmacology & Therapeutics. 109: 198-209. PMID 16095713 DOI: 10.1016/J.Pharmthera.2005.07.002  0.369
2005 Gold R, Hartung HP. Towards individualised multiple-sclerosis therapy. The Lancet. Neurology. 4: 693-4. PMID 16239174 DOI: 10.1016/S1474-4422(05)70205-2  0.315
2005 Hartung HP. Early treatment and dose optimisation BENEFIT and BEYOND. Journal of Neurology. iii44-iii50. PMID 16170501 DOI: 10.1007/S00415-005-2017-Z  0.337
2005 Zickler P, Seitz RJ, Hartung HP, Hefter H. Bilateral medullary pyramid infarction. Neurology. 64: 1801. PMID 15911818 DOI: 10.1212/01.Wnl.0000148483.84261.49  0.492
2005 Köller H, Schroeter M, Kieseier BC, Hartung HP. Chronic inflammatory demyelinating polyneuropathy--update on pathogenesis, diagnostic criteria and therapy. Current Opinion in Neurology. 18: 273-8. PMID 15891411 DOI: 10.1097/01.Wco.0000169744.14288.D1  0.329
2005 Kieseier BC, Hemmer B, Hartung HP. Multiple sclerosis--novel insights and new therapeutic strategies. Current Opinion in Neurology. 18: 211-20. PMID 15891402 DOI: 10.1097/01.Wco.0000169735.60922.Fb  0.363
2005 Menge T, Hartung HP, Stüve O. Statins--a cure-all for the brain? Nature Reviews. Neuroscience. 6: 325-31. PMID 15803163 DOI: 10.1038/Nrn1652  0.319
2005 Köller H, Kieseier BC, Jander S, Hartung HP. Chronic inflammatory demyelinating polyneuropathy. The New England Journal of Medicine. 352: 1343-56. PMID 15800230 DOI: 10.1056/Nejmra041347  0.311
2005 Cepok S, Rosche B, Grummel V, Vogel F, Zhou D, Sayn J, Sommer N, Hartung HP, Hemmer B. Short-lived plasma blasts are the main B cell effector subset during the course of multiple sclerosis. Brain : a Journal of Neurology. 128: 1667-76. PMID 15800022 DOI: 10.1093/Brain/Awh486  0.384
2005 Mitsdoerffer M, Schreiner B, Kieseier BC, Neuhaus O, Dichgans J, Hartung HP, Weller M, Wiendl H. Monocyte-derived HLA-G acts as a strong inhibitor of autologous CD4 T cell activation and is upregulated by interferon-beta in vitro and in vivo: rationale for the therapy of multiple sclerosis. Journal of Neuroimmunology. 159: 155-64. PMID 15652415 DOI: 10.1016/J.Jneuroim.2004.09.016  0.329
2005 Amato MP, Grimaud J, Achiti I, Bartolozzi ML, Adeleine P, Hartung HP, Kappos L, Thompson A, Trojano M, Vukusic S, Confavreux C. European validation of a standardized clinical description of multiple sclerosis. Journal of Neurology. 251: 1472-80. PMID 15645346 DOI: 10.1007/S00415-004-0567-0  0.305
2004 Neuhaus O, Kieseier BC, Hartung HP. Mitoxantrone (Novantrone) in multiple sclerosis: new insights. Expert Review of Neurotherapeutics. 4: 17-26. PMID 15853611 DOI: 10.1586/14737175.4.1.17  0.362
2004 Seitz RJ, Kleiser R, Bütefisch CM, Jörgens S, Neuhaus O, Hartung HP, Wittsack HJ, Sturm V, Hermann MM. Bimanual recoupling by visual cueing in callosal disconnection. Neurocase. 10: 316-25. PMID 15788269 DOI: 10.1080/13554790490505373  0.454
2004 Hartung H, Bar-Or A, Zoukos Y. What do we know about the mechanism of action of disease-modifying treatments in MS? Journal of Neurology. 251. PMID 15549350 DOI: 10.1007/S00415-004-1504-Y  0.409
2004 Kieseier BC, Kiefer R, Gold R, Hemmer B, Willison HJ, Hartung HP. Advances in understanding and treatment of immune-mediated disorders of the peripheral nervous system. Muscle & Nerve. 30: 131-56. PMID 15266629 DOI: 10.1002/Mus.20076  0.345
2004 Hartung HP, Munschauer FE. Assessment and management of neutralizing antibodies in patients with multiple sclerosis. Journal of Neurology. II40-2. PMID 15264111 DOI: 10.1007/S00415-004-1207-4  0.352
2004 Billiau A, Kieseier BC, Hartung HP. Biologic role of interferon beta in multiple sclerosis. Journal of Neurology. II10-4. PMID 15264107 DOI: 10.1007/S00415-004-1203-8  0.313
2004 Neuhaus O, Kieseier BC, Hartung HP. Mechanisms of mitoxantrone in multiple sclerosis--what is known? Journal of the Neurological Sciences. 223: 25-7. PMID 15261556 DOI: 10.1016/J.Jns.2004.04.015  0.36
2004 Kieseier BC, Archelos JJ, Hartung HP. Different effects of simvastatin and interferon beta on the proteolytic activity of matrix metalloproteinases. Archives of Neurology. 61: 929-32. PMID 15210533 DOI: 10.1001/Archneur.61.6.929  0.317
2004 Neuhaus O, Stüve O, Zamvil SS, Hartung HP. Are statins a treatment option for multiple sclerosis? The Lancet. Neurology. 3: 369-71. PMID 15157852 DOI: 10.1016/S1474-4422(04)00770-7  0.381
2004 Neuhaus O, Kieseier BC, Klimke A, Gaebel W, Hohlfeld R, Hartung HP. [Cannabinoids in multiple sclerosis. Opportunity or hazard?]. Der Nervenarzt. 75: 1022-6. PMID 15156287 DOI: 10.1007/S00115-004-1738-Z  0.335
2004 Hu W, Mathey E, Hartung HP, Kieseier BC. Cyclo-oxygenases and prostaglandins in acute inflammatory demyelination of the peripheral nerve. Neurology. 61: 1774-9. PMID 14694045 DOI: 10.1212/01.Wnl.0000098884.75756.4D  0.309
2004 Gold R, Kieseier BC, Hartung H. Neue Therapieansätze bei der Multiplen Sklerose Psychoneuro. 30: 375-379. DOI: 10.1055/S-2004-831081  0.375
2004 Zettl UK, Mix E, Hartung H. Diagnostische Kriterien der Multiplen Sklerose - Aktuelle Aspekte Psychoneuro. 30: 370-374. DOI: 10.1055/S-2004-831080  0.302
2004 Hartung H, Schellekens H, Munschauer FE. Neutralizing antibodies to interferon beta in patients with multiple sclerosis: scientific background and clinical implications Journal of Neurology. 251: ii1-ii3. DOI: 10.1007/S00415-004-1201-X  0.32
2003 Schroeter M, Stoll G, Weissert R, Hartung HP, Lassmann H, Jander S. CD8+ phagocyte recruitment in rat experimental autoimmune encephalomyelitis: association with inflammatory tissue destruction. The American Journal of Pathology. 163: 1517-24. PMID 14507658 DOI: 10.1016/S0002-9440(10)63508-0  0.309
2003 Kieseier BC, Hartung HP. Therapeutic strategies in the Guillain-Barré syndrome. Seminars in Neurology. 23: 159-68. PMID 12894381 DOI: 10.1055/S-2003-41132  0.357
2003 Wiendl H, Neuhaus O, Mehling M, Wintterle S, Schreiner B, Mitsdoerffer M, Wienhold W, Weissert R, Wessels J, Hartung H, Weller M, Tolosa E, Melms A. The CD28 related molecule ICOS: T cell modulation in the presence and absence of B7.1/2 and regulational expression in multiple sclerosis Journal of Neuroimmunology. 140: 177-187. PMID 12864987 DOI: 10.1016/S0165-5728(03)00172-3  0.344
2003 Kieseier BC, Hartung HP. Multiple paradigm shifts in multiple sclerosis. Current Opinion in Neurology. 16: 247-52. PMID 12858058 DOI: 10.1097/01.Wco.0000073923.19076.75  0.338
2003 Kieseier BC, Pischel H, Neuen-Jacob E, Tourtellotte WW, Hartung HP. ADAM-10 and ADAM-17 in the inflamed human CNS. Glia. 42: 398-405. PMID 12730960 DOI: 10.1002/Glia.10226  0.384
2003 Hemmer B, Kieseier B, Cepok S, Hartung HP. New immunopathologic insights into multiple sclerosis. Current Neurology and Neuroscience Reports. 3: 246-55. PMID 12691630 DOI: 10.1007/S11910-003-0085-Y  0.391
2003 Kastenbauer S, Koedel U, Wick M, Kieseier BC, Hartung H, Pfister H. CSF and serum levels of soluble fractalkine (CX3CL1) in inflammatory diseases of the nervous system. Journal of Neuroimmunology. 137: 210-217. PMID 12667665 DOI: 10.1016/S0165-5728(03)00085-7  0.33
2003 Neuhaus O, Archelos JJ, Hartung HP. Immunomodulation in multiple sclerosis: from immunosuppression to neuroprotection. Trends in Pharmacological Sciences. 24: 131-8. PMID 12628358 DOI: 10.1016/S0165-6147(03)00028-2  0.397
2003 Enzinger C, Ropele S, Strasser-Fuchs S, Kapeller P, Schmidt H, Poltrum B, Schmidt R, Hartung HP, Fazekas F. Lower levels of N-acetylaspartate in multiple sclerosis patients with the apolipoprotein E epsilon4 allele. Archives of Neurology. 60: 65-70. PMID 12533090 DOI: 10.1001/Archneur.60.1.65  0.316
2003 Stangel M, Hartung HP. Remyelinating strategies for the treatment of multiple sclerosis. Progress in Neurobiology. 68: 361-76. PMID 12531235 DOI: 10.1016/S0301-0082(02)00105-3  0.378
2003 Kieseier BC, Dalakas MC, Hartung HP. Immune mechanisms in chronic inflammatory demyelinating neuropathy. Neurology. 59: S7-12. PMID 12499465 DOI: 10.1212/Wnl.59.12_Suppl_6.S7  0.365
2003 Neuhaus O, Kieseier BC, Archelos JJ, Hartung H. Response to Mousavizadeh et al.: Oxidative toxicity and glutamate excitotoxicity in multiple sclerosis Trends in Pharmacological Sciences. 24: 564-565. DOI: 10.1016/J.Tips.2003.09.005  0.322
2002 Hartung HP, Gonsette R, König N, Kwiecinski H, Guseo A, Morrissey SP, Krapf H, Zwingers T, Albrecht H, Basedow-Rajwich B, Hofmeister R, Pöllmann W, Starck M, Beer K, Hopf HC, et al. Mitoxantrone in progressive multiple sclerosis: A placebo-controlled, double-blind, randomised, multicentre trial Lancet. 360: 2018-2025. PMID 12504397 DOI: 10.1016/S0140-6736(02)12023-X  0.333
2002 Hemmer B, Archelos JJ, Hartung HP. New concepts in the immunopathogenesis of multiple sclerosis. Nature Reviews. Neuroscience. 3: 291-301. PMID 11967559 DOI: 10.1038/Nrn784  0.41
2001 Feasby TE, Hartung H. Drain the roots A new treatment for Guillain–Barré syndrome? Neurology. 57: 753-754. PMID 11551999 DOI: 10.1212/Wnl.57.5.753  0.34
2001 Korn T, Toyka K, Hartung H, Jung S. Suppression of experimental autoimmune neuritis by leflunomide. Brain. 124: 1791-1802. PMID 11522581 DOI: 10.1093/Brain/124.9.1791  0.327
2001 Andorfer B, Kieseier BC, Mathey E, Armati P, Pollard J, Oka N, Hartung HP. Expression and distribution of transcription factor NF-kappaB and inhibitor IkappaB in the inflamed peripheral nervous system. Journal of Neuroimmunology. 116: 226-32. PMID 11438178 DOI: 10.1016/S0165-5728(01)00306-X  0.317
2001 Hartung H. ADEM: distinct disease or part of the MS spectrum? Neurology. 56: 1257-1260. PMID 11376169 DOI: 10.1212/Wnl.56.10.1257  0.344
2000 Kiefer R, Dangond F, Mueller M, Toyka KV, Hafler DA, Hartung HP. Enhanced B7 costimulatory molecule expression in inflammatory human sural nerve biopsies Journal of Neurology Neurosurgery and Psychiatry. 69: 362-368. PMID 10945811 DOI: 10.1046/J.1529-8027.2001.01008-15.X  0.309
2000 Schmidt J, Gold R, Schönrock L, Zettl UK, Hartung H, Toyka KV. T-cell apoptosis in situ in experimental autoimmune encephalomyelitis following methylprednisolone pulse therapy Brain. 123: 1431-1441. PMID 10869055 DOI: 10.1093/Brain/123.7.1431  0.311
2000 Archelos JJ, Hartung HP. Pathogenetic role of autoantibodies in neurological diseases. Trends in Neurosciences. 23: 317-27. PMID 10856942 DOI: 10.1016/S0166-2236(00)01575-7  0.32
2000 Hartung HP, Kieseier BC. The role of matrix metalloproteinases in autoimmune damage to the central and peripheral nervous system. Journal of Neuroimmunology. 107: 140-7. PMID 10854648 DOI: 10.1016/S0165-5728(00)00225-3  0.314
2000 Gold R, Oelschläger M, Pepinsky RB, Sommer C, Hartung HP, Toyka KV. Increased lipocortin-1 (annexin-1) expression in the sciatic nerve of Lewis rats with experimental autoimmune neuritis. Acta Neuropathologica. 98: 583-9. PMID 10603033 DOI: 10.1007/S004010051122  0.344
1999 Wewetzer K, Archelos JJ, Hartung HP, Seilheimer B, Christ B. The monoclonal antibody 23E9 defines a novel developmentally-regulated Schwann cell surface antigen. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 17: 715-25. PMID 10568688 DOI: 10.1016/S0736-5748(99)00046-5  0.302
1999 Hartung HP, Kieseier RC. Antibody responses in the Guillain-Barré syndrome. Journal of the Neurological Sciences. 168: 75-7. PMID 10526186 DOI: 10.1016/S0022-510X(99)00190-2  0.308
1999 Chan A, Gold R, Giegerich G, Herrmann T, Jung S, Toyka KV, Hartung H. Usage of vβ3.3 T-cell receptor by myelin basic protein-specific encephalitogenic T-cell lines in the Lewis rat Journal of Neuroscience Research. 58: 214-225. PMID 10502278 DOI: 10.1002/(Sici)1097-4547(19991015)58:2<214::Aid-Jnr2>3.0.Co;2-6  0.3
1999 Noseworthy JH, Gold R, Hartung H. Treatment of multiple sclerosis: recent trials and future perspectives. Current Opinion in Neurology. 12: 279-293. PMID 10499173 DOI: 10.1097/00019052-199906000-00007  0.339
1999 Kieseier BC, Seifert T, Giovannoni G, Hartung H. Matrix metalloproteinases in inflammatory demyelination Targets for treatment Neurology. 53: 20-20. PMID 10408531 DOI: 10.1212/Wnl.53.1.20  0.32
1999 Archelos JJ, Previtali SC, Hartung HP. The role of integrins in immune-mediated diseases of the nervous system. Trends in Neurosciences. 22: 30-8. PMID 10088997 DOI: 10.1016/S0166-2236(98)01287-9  0.375
1998 Archelos JJ, Jung S, Rinner W, Lassmann H, Miyasaka M, Hartung HP. Role of the leukocyte-adhesion molecule L-selectin in experimental autoimmune encephalomyelitis. Journal of the Neurological Sciences. 159: 127-34. PMID 9741395 DOI: 10.1016/S0022-510X(98)00154-3  0.327
1998 Steck AJ, Schaeren-Wiemers N, Hartung H. Demyelinating Inflammatory Neuropathies, Including Guillain-Barre Syndrome Current Opinion in Neurology. 11: 311-318. PMID 9725076 DOI: 10.1097/00019052-199808000-00006  0.349
1998 Archelos JJ, Trotter J, Previtali S, Weißbrich B, Toyka KV, Hartung HP. Isolation and characterization of an oligodendrocyte precursor-derived B-cell epitope in multiple sclerosis Annals of Neurology. 43: 15-24. PMID 9450764 DOI: 10.1002/Ana.410430107  0.343
1998 Archelos JJ, Fortwängler T, Hartung HP. Attenuation of experimental autoimmune neuritis in the Lewis rat by treatment with an antibody to L-selectin. Neuroscience Letters. 235: 9-12. PMID 9389583 DOI: 10.1016/S0304-3940(97)00692-7  0.318
1997 Jung S, Donhauser T, Toyka KV, Hartung H. Propentofylline and Iloprost Suppress the Production of TNF-αby Macrophages but Fail to Ameliorate Experimental Autoimmune Encephalomyelitis in Lewis Rats Journal of Autoimmunity. 10: 519-529. PMID 9451591 DOI: 10.1006/Jaut.1997.0159  0.339
1997 Fazekas F, Offenbacher H, Hartung H. What Is the Role of Ancillary Investigations in Establishing the Diagnosis of Multiple Sclerosis European Neurology. 38: 255-257. PMID 9434082 DOI: 10.1159/000113390  0.32
1997 Gaupp S, Hartung HP, Toyka K, Jung S. Modulation of experimental autoimmune neuritis in Lewis rats by oral application of myelin antigens. Journal of Neuroimmunology. 79: 129-37. PMID 9394785 DOI: 10.1016/S0165-5728(97)00115-X  0.353
1997 Gold R, Hartung HP, Lassmann H. T-cell apoptosis in autoimmune diseases: termination of inflammation in the nervous system and other sites with specialized immune-defense mechanisms. Trends in Neurosciences. 20: 399-404. PMID 9292968 DOI: 10.1016/S0166-2236(97)01079-5  0.309
1997 Archelos JJ, Hartung H. The role of adhesion molecules in multiple sclerosis: biology, pathogenesis and therapeutic implications Molecular Medicine Today. 3: 310-321. PMID 9257299 DOI: 10.1016/S1357-4310(97)01066-6  0.383
1997 Köller H, Siebler M, Hartung HP. Immunologically induced electrophysiological dysfunction: Implications for inflammatory diseases of the CNS and PNS Progress in Neurobiology. 52: 1-26. PMID 9185232 DOI: 10.1016/S0301-0082(96)00065-2  0.341
1997 Jung S, Toyka KV, Hartung HP. Soluble complement receptor type 1 inhibits experimental autoimmune neuritis in Lewis rats. Neuroscience Letters. 200: 167-70. PMID 9064603 DOI: 10.1016/0304-3940(95)12115-K  0.334
1997 Weishaupt A, Gold R, Gaupp S, Giegerich G, Hartung H, Toyka KV. Antigen therapy eliminates T cell inflammation by apoptosis: Effective treatment of experimental autoimmune neuritis with recombinant myelin protein P2 Proceedings of the National Academy of Sciences of the United States of America. 94: 1338-1343. PMID 9037054 DOI: 10.1073/Pnas.94.4.1338  0.339
1997 Hartung HP, Willison H, Jung S, Pette M, Toyka KV, Giegerich G. Autoimmune responses in peripheral nerve. Springer Seminars in Immunopathology. 18: 97-123. PMID 8984683 DOI: 10.1007/Bf00792612  0.341
1996 Zielasek J, Hartung H. Molecular mechanisms of microglial activation. Advances in Neuroimmunology. 6: 191-222. PMID 8876774 DOI: 10.1016/0960-5428(96)00017-4  0.328
1996 Toyka KV, Hartung HP. Chronic inflammatory polyneuritis and neuropathies. Current Opinion in Neurology. 9: 240-50. PMID 8839619 DOI: 10.1097/00019052-199606000-00016  0.357
1996 Giovannoni G, Hartung H. The Immunopathogenesis Of Multiple Sclerosis And Guillain-Barre Syndrome Current Opinion in Neurology. 9: 165-177. PMID 8839607 DOI: 10.1097/00019052-199606000-00004  0.382
1996 Morrissey SP, Deichmann R, Syha J, Simonis C, Zettl U, Archelos JJ, Jung S, Stodal H, Lassmann H, Toyka KV, Haase A, Hartung HP. Partial inhibition of AT-EAE by an antibody to ICAM-1: Clinico-histological and MRI studies Journal of Neuroimmunology. 69: 85-93. PMID 8823379 DOI: 10.1016/0165-5728(96)00064-1  0.347
1996 Jung S, Toyka K, Hartung H. T cell directed immunotherapy of inflammatory demyelination in the peripheral nervous system : Potent suppression of the effector phase of experimental autoimmune neuritis by anti-CD2 antibodies Brain. 119: 1079-1090. PMID 8813272 DOI: 10.1093/Brain/119.4.1079  0.35
1996 Jung S, Zielasek J, Köllner G, Donhauser T, Toyka K, Hartung HP. Preventive but not therapeutic application of Rolipram ameliorates experimental autoimmune encephalomyelitis in Lewis rats. Journal of Neuroimmunology. 68: 1-11. PMID 8784254 DOI: 10.1016/0165-5728(96)00051-3  0.329
1996 Morrissey SP, Stodal H, Zettl U, Simonis C, Jung S, Kiefer R, Lassmann H, Hartung HP, Haase A, Toyka KV. In vivo MRI and its histological correlates in acute adoptive transfer experimental allergic encephalomyelitis: Quantification of inflammation and oedema Brain. 119: 239-248. PMID 8624685 DOI: 10.1093/Brain/119.1.239  0.307
1996 Schmidt B, Toyka KV, Kiefer R, Full J, Hartung H, Pollard J. Inflammatory infiltrates in sural nerve biopsies in Guillain-Barré syndrome and chronic inflammatory demyelinating neuropathy Muscle & Nerve. 19: 474-487. PMID 8622727 DOI: 10.1002/(Sici)1097-4598(199604)19:4<474::Aid-Mus8>3.0.Co;2-9  0.333
1995 Hartung HP, Pollard JD, Harvey GK, Toyka KV. Immunopathogenesis and treatment of the Guillain-Barré syndrome--Part I. Muscle & Nerve. 18: 137-53. PMID 7823972 DOI: 10.1002/Mus.880180202  0.343
1995 Hartung HP, Archelos JJ, Zielasek J, Gold R, Koltzenburg M, Reiners KH, Toyka KV. Circulating adhesion molecules and inflammatory mediators in demyelination: a review. Neurology. 45: S22-32. PMID 7783908 DOI: 10.1212/Wnl.45.6_Suppl_6.S22  0.32
1995 Gold R, Toyka KV, Hartung HP. Synergistic effect of IFN-gamma and TNF-alpha on expression of immune molecules and antigen presentation by Schwann cells. Cellular Immunology. 165: 65-70. PMID 7671325 DOI: 10.1006/Cimm.1995.1187  0.308
1995 Zettl UK, Gold R, Toyka KV, Hartung H. Intravenous glucocorticosteroid treatment augments apoptosis of inflammatory T cells in experimental autoimmune neuritis (EAN) of the Lewis rat. Journal of Neuropathology and Experimental Neurology. 54: 540-547. PMID 7602327 DOI: 10.1097/00005072-199507000-00008  0.335
1995 Polman CH, Hartung H. The treatment of multiple sclerosis: current and future. Current Opinion in Neurology. 8: 200-209. PMID 7551119 DOI: 10.1097/00019052-199506000-00008  0.371
1995 Hartung H. Pathogenesis of inflammatory demyelination: implications for therapy. Current Opinion in Neurology. 8: 191-199. PMID 7551118 DOI: 10.1097/00019052-199506000-00007  0.306
1995 Jung S, Toyka K, Hartung H. Suppression of experimental autoimmune encephalomyelitis in Lewis rats by antibodies against CD2. European Journal of Immunology. 25: 1391-1398. PMID 7539758 DOI: 10.1002/Eji.1830250538  0.339
1995 Hartung H. Basic immunology and the pathogenesis of multiple sclerosis Journal of Neuroimmunology. 17-17. DOI: 10.1016/0165-5728(95)98909-U  0.379
1994 Jung S, Huitinga I, Schmidt B, Zielasek J, Dijkstra CD, Toyka KV, Hartung HP. Selective elimination of macrophages by dichlormethylene diphosphonate-containing liposomes suppresses experimental autoimmune neuritis. Journal of the Neurological Sciences. 119: 195-202. PMID 8277335 DOI: 10.1016/0022-510X(93)90134-K  0.322
1993 Hartung H. Immune‐mediated demyelination Annals of Neurology. 33: 563-567. PMID 8498835 DOI: 10.1002/Ana.410330602  0.379
1993 Archelos JJ, Mäurer M, Jung S, Toyka KV, Hartung H. Suppression of experimental allergic neuritis by an antibody to the intercellular adhesion molecule ICAM-1 Brain. 116: 1043-1058. PMID 7693297 DOI: 10.1093/Brain/116.5.1043  0.346
1993 Archelos JJ, Jung S, Mäurer M, Schmied M, Lassmann H, Tamatani T, Miyasaka M, Toyka KV, Hartung H. Inhibition of experimental autoimmune encephalomyelitis by an antibody to the intercellular adhesion molecule ICAM-1. Annals of Neurology. 34: 145-154. PMID 7687838 DOI: 10.1002/Ana.410340209  0.336
1992 Schmidt B, Stoll G, Meide PVD, Jung S, Hartung H. Transient Cellular Expression Of Γ-Interferon In Myelin-Induced And T-Cell Line-Mediated Experimental Autoimmune Neuritis Brain. 115: 1633-1646. PMID 1486454 DOI: 10.1093/Brain/115.6.1633  0.326
1992 Hartung HP, Jung S, Stoll G, Zielasek J, Schmidt B, Archelos JJ, Toyka KV. Inflammatory mediators in demyelinating disorders of the CNS and PNS. Journal of Neuroimmunology. 40: 197-210. PMID 1331168 DOI: 10.1016/0165-5728(92)90134-7  0.358
1992 Stoll G, Hartung H. The role of macrophages in degeneration and immune-mediated demyelination of the peripheral nervous system Advances in Neuroimmunology. 2: 163-179. DOI: 10.1016/S0960-5428(06)80046-X  0.339
1991 Hartung H, Reiners K, Schmidt B, Stoll G, Toyka KV. Serum interleukin-2 concentrations in Guillain-Barré syndrome and chronic idiopathic demyelinating polyradiculoneuropathy: Comparison with other neurological diseases of presumed immunopathogenesis Annals of Neurology. 30: 48-53. PMID 1929228 DOI: 10.1002/Ana.410300110  0.31
1990 Schmidt B, Stoll G, Hartung H, Heininger K, Schäfer B, Toyka KV. Macrophages but not Schwann cells express Ia antigen in experimental autoimmune neuritis. Annals of Neurology. 28: 70-77. PMID 2375636 DOI: 10.1002/Ana.410280113  0.333
1990 Hartung H, Schäfer B, Meide PHVD, Fierz W, Heininger K, Toyka KV. The role of interferon-gamma in the pathogenesis of experimental autoimmune disease of the peripheral nervous system. Annals of Neurology. 27: 247-257. PMID 2158267 DOI: 10.1002/Ana.410270306  0.362
1989 Seitz RJ, Reiners K, Himmelmann F, Heininger K, Hartung HP, Toyka KV. The blood-nerve barrier in Wallerian degeneration: a sequential long-term study. Muscle & Nerve. 12: 627-35. PMID 2506446 DOI: 10.1002/Mus.880120803  0.492
1989 Heininger K, Fierz W, Schäfer B, Hartung H, Wehling P, Toyka KV. Electrophysiological Investigations In Adoptively Transferred Experimental Autoimmune Encephalomyelitis In The Lewis Rat Brain. 112: 537-552. PMID 2468392 DOI: 10.1093/Brain/112.2.537  0.302
1988 Heininger K, Schäfer B, Hartung H, Fierz W, Linington C, Toyka KV. The role of macrophages in experimental autoimmune neuritis induced by a P2-specific T-cell line. Annals of Neurology. 23: 326-331. PMID 3260088 DOI: 10.1002/Ana.410230403  0.341
1988 Hartung H, Schäfer B, Heininger K, Stoll G, Toyka KV. The role of macrophages and eicosanoids in the pathogenesis of experimental allergic neuritis. Serial clinical, electrophysiological, biochemical and morphological observations. Brain. 111: 1039-1059. PMID 2846115 DOI: 10.1093/Brain/111.5.1039  0.353
1988 Hartung HP, Schäfer B, Fierz W, Heininger K, Toyka KV. Ciclosporin A prevents P2 T cell line-mediated experimental autoimmune neuritis (AT-EAN) in rat. Neuroscience Letters. 83: 195-200. PMID 2450307 DOI: 10.1016/0304-3940(87)90240-0  0.348
Low-probability matches (unlikely to be authored by this person)
2008 Hughes RA, Donofrio P, Bril V, Dalakas MC, Deng C, Hanna K, Hartung HP, Latov N, Merkies IS, van Doorn PA. Intravenous immune globulin (10% caprylate-chromatography purified) for the treatment of chronic inflammatory demyelinating polyradiculoneuropathy (ICE study): a randomised placebo-controlled trial. The Lancet. Neurology. 7: 136-44. PMID 18178525 DOI: 10.1016/S1474-4422(07)70329-0  0.3
2019 Hartung HP, Graf J, Aktas O, Mares J, Barnett MH. Diagnosis of multiple sclerosis: revisions of the McDonald criteria 2017 - continuity and change. Current Opinion in Neurology. PMID 30985371 DOI: 10.1097/Wco.0000000000000699  0.3
2018 Jensen PEH, Warnke C, Ingenhoven K, Piccoli L, Gasis M, Hermanrud C, Fernandez-Rodriguez BM, Ryner M, Kramer D, Link J, Ramanujam R, Auer M, Buck D, Grummel V, Bertotti E, ... ... Hartung HP, et al. Detection and kinetics of persistent neutralizing anti-interferon-beta antibodies in patients with multiple sclerosis. Results from the ABIRISK prospective cohort study. Journal of Neuroimmunology. 326: 19-27. PMID 30447419 DOI: 10.1016/J.Jneuroim.2018.11.002  0.3
1989 Hartung HP, Schäfer B, Diamantstein T, Fierz W, Heininger K, Toyka KV. Suppression of P2-T cell line-mediated experimental autoimmune neuritis by interleukin-2 receptor targeted monoclonal antibody ART 18. Brain Research. 489: 120-8. PMID 2787191 DOI: 10.1016/0006-8993(89)90014-0  0.3
2018 Buck D, Andlauer TF, Igl W, Wicklein EM, Mühlau M, Weber F, Köchert K, Pohl C, Arnason B, Comi G, Cook S, Filippi M, Hartung HP, Jeffery D, Kappos L, et al. Effect of HLA-DRB1 alleles and genetic variants on the development of neutralizing antibodies to interferon beta in the BEYOND and BENEFIT trials. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458518763089. PMID 29521573 DOI: 10.1177/1352458518763089  0.299
2011 Hartung HP, Lehmann HC, Willison HJ. Peripheral neuropathies: Establishing common clinical research standards for CIDP. Nature Reviews. Neurology. 7: 250-1. PMID 21537353 DOI: 10.1038/Nrneurol.2011.46  0.299
2015 Wiendl H, Elger C, Förstl H, Hartung HP, Oertel W, Reichmann H, Schwab S. Gaps Between Aims and Achievements in Therapeutic Modification of Neuronal Damage ("Neuroprotection"). Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 12: 449-54. PMID 25773662 DOI: 10.1007/S13311-015-0348-8  0.299
1996 Zettl UK, Gold R, Toyka KV, Hartung H. In situ demonstration of T cell activation and elimination in the peripheral nervous system during experimental autoimmune neuritis in the Lewis rat. Acta Neuropathologica. 91: 360-367. PMID 8928612 DOI: 10.1007/S004010050437  0.298
1995 Harvey GK, Toyka KV, Zielasek J, Kiefer R, Simonis C, Hartung H. Failure of anti-GM1 IgG or IgM to induce conduction block following intraneural transfer Muscle & Nerve. 18: 388-394. PMID 7715623 DOI: 10.1002/Mus.880180404  0.298
2019 Merkies ISJ, van Schaik IN, Léger JM, Bril V, van Geloven N, Hartung HP, Lewis RA, Sobue G, Lawo JP, Durn BL, Cornblath DR, De Bleecker JL, Sommer C, Robberecht W, Saarela M, et al. Efficacy and safety of IVIG in CIDP: combined data of the PRIMA and PATH studies. Journal of the Peripheral Nervous System : Jpns. PMID 30672091 DOI: 10.1111/Jns.12302  0.298
1993 Enders U, Karch H, Toyka KV, Michels M, Zielasek J, Pette M, Heesemann J, Hartung H. The spectrum of immune responses to Campylobacter jejuni and glycoconjugates in Guillain-Barré syndrome and in other neuroimmunological disorders Annals of Neurology. 34: 136-144. PMID 8338338 DOI: 10.1002/Ana.410340208  0.297
1992 Hartung H. Effector mechanisms of inflammatory demyelination Journal of Neuroimmunology. 40: 128. DOI: 10.1016/0165-5728(92)90234-C  0.297
2019 Cohen JA, Comi G, Selmaj KW, Bar-Or A, Arnold DL, Steinman L, Hartung HP, Montalban X, Kubala Havrdová E, Cree BAC, Sheffield JK, Minton N, Raghupathi K, Huang V, Kappos L, et al. Safety and efficacy of ozanimod versus interferon beta-1a in relapsing multiple sclerosis (RADIANCE): a multicentre, randomised, 24-month, phase 3 trial. The Lancet. Neurology. PMID 31492652 DOI: 10.1016/S1474-4422(19)30238-8  0.297
1994 Zettl UK, Gold R, Hartung HP, Toyka KV. Apoptotic cell death of T-lymphocytes in experimental autoimmune neuritis of the Lewis rat. Neuroscience Letters. 176: 75-9. PMID 7970241 DOI: 10.1016/0304-3940(94)90875-3  0.296
2015 Kremer D, Hartung HP, Küry P. Targeting semaphorins in MS as a treatment strategy to promote remyelination: A tale of mice, rats and men. Multiple Sclerosis (Houndmills, Basingstoke, England). 21: 1616-7. PMID 26432852 DOI: 10.1177/1352458515608693  0.296
2019 Comi G, Kappos L, Selmaj KW, Bar-Or A, Arnold DL, Steinman L, Hartung HP, Montalban X, Kubala Havrdová E, Cree BAC, Sheffield JK, Minton N, Raghupathi K, Ding N, Cohen JA, et al. Safety and efficacy of ozanimod versus interferon beta-1a in relapsing multiple sclerosis (SUNBEAM): a multicentre, randomised, minimum 12-month, phase 3 trial. The Lancet. Neurology. PMID 31492651 DOI: 10.1016/S1474-4422(19)30239-X  0.295
2018 Haupts MR, Spill-Askeridis P, Humpert M, Seidel D, Hartung HP. Acute exacerbations after decades of non-active chronic multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458518754365. PMID 29363379 DOI: 10.1177/1352458518754365  0.295
1996 Zielasek J, Müller B, Hartung HP. Inhibition of cytokine-inducible nitric oxide synthase in rat microglia and murine macrophages by methyl-2,5-dihydroxycinnamate. Neurochemistry International. 29: 83-7. PMID 8808792 DOI: 10.1016/0197-0186(95)00136-0  0.295
2006 Schneider-Gold C, Hartung HP, Gold R. Mycophenolate mofetil and tacrolimus: new therapeutic options in neuroimmunological diseases. Muscle & Nerve. 34: 284-91. PMID 16583368 DOI: 10.1002/Mus.20543  0.295
2016 Menge T, Dubey D, Warnke C, Hartung HP, Stüve O. Ocrelizumab for the treatment of relapsing-remitting multiple sclerosis. Expert Review of Neurotherapeutics. PMID 27552111 DOI: 10.1080/14737175.2016.1227242  0.294
2018 Göttle P, Manousi A, Kremer D, Reiche L, Hartung HP, Küry P. Teriflunomide promotes oligodendroglial differentiation and myelination. Journal of Neuroinflammation. 15: 76. PMID 29534752 DOI: 10.1186/s12974-018-1110-z  0.294
1996 Gold R, Zielasek J, Kiefer R, Toyka KV, Hartung H. Secretion of Nitrite by Schwann Cells and Its Effect on T-Cell Activationin Vitro Cellular Immunology. 168: 69-77. PMID 8599841 DOI: 10.1006/Cimm.1996.0050  0.294
2010 Bril V, Banach M, Dalakas MC, Deng C, Donofrio P, Hanna K, Hartung HP, Hughes RA, Katzberg H, Latov N, Merkies IS, Van Doorn PA. Electrophysiologic correlations with clinical outcomes in CIDP. Muscle & Nerve. 42: 492-7. PMID 20665514 DOI: 10.1002/Mus.21733  0.293
2001 Jung S, Gaupp S, Hartung HP, Toyka KV. Oral tolerance in experimental autoimmune neuritis (EAN) of the Lewis rat II. Adjuvant effects and bystander suppression in P2 peptide-induced EAN Journal of Neuroimmunology. 116: 21-28. PMID 11311326 DOI: 10.1016/S0165-5728(01)00276-4  0.293
2015 Chin RL, Deng C, Bril V, Hartung HP, Merkies IS, Donofrio PD, van Doorn PA, Dalakas MC, Latov N. Follow-up nerve conduction studies in CIDP after treatment with IGIV-C: Comparison of patients with and without subsequent relapse. Muscle & Nerve. PMID 25728021 DOI: 10.1002/Mus.24624  0.292
2012 Fernandez O, Berger T, Hartung HP, Putzki N. Historical overview of the rationale for the pharmacological use of prolonged-release fampridine in multiple sclerosis. Expert Review of Clinical Pharmacology. 5: 649-65. PMID 23146002 DOI: 10.1586/Ecp.12.59  0.292
1988 Hartung H, Schäfer B, Heininger K, Toyka KV. Suppression of experimental autoimmune neuritis by the oxygen radical scavengers superoxide dismutase and catalase. Annals of Neurology. 23: 453-460. PMID 3260463 DOI: 10.1002/Ana.410230505  0.292
1993 Stoll G, Jung S, Jander S, van der Meide P, Hartung HP. Tumor necrosis factor-alpha in immune-mediated demyelination and Wallerian degeneration of the rat peripheral nervous system. Journal of Neuroimmunology. 45: 175-82. PMID 8331160 DOI: 10.1016/0165-5728(93)90178-2  0.291
2007 Kieseier BC, Wiendl H, Hartung HP. The inflamed peripheral nervous system: update on immune therapies. Current Opinion in Neurology. 19: 433-6. PMID 16969151 DOI: 10.1097/01.Wco.0000245364.51823.3B  0.291
2008 Hoffmann S, Cepok S, Grummel V, Lehmann-Horn K, Hackermüller J, Stadler PF, Hartung H, Berthele A, Deisenhammer F, Wassmuth R, Hemmer B. HLA-DRB10401 and HLA-DRB10408 Are Strongly Associated with the Development of Antibodies against Interferon-β Therapy in Multiple Sclerosis The American Journal of Human Genetics. 83: 541. DOI: 10.1016/J.Ajhg.2008.09.016  0.291
2017 Comi G, Hartung HP, Bakshi R, Williams IM, Wiendl H. Benefit-Risk Profile of Sphingosine-1-Phosphate Receptor Modulators in Relapsing and Secondary Progressive Multiple Sclerosis. Drugs. PMID 28905255 DOI: 10.1007/S40265-017-0814-1  0.29
2012 Walter J, Hartung HP, Dihné M. Interferon gamma and sonic hedgehog signaling are required to dysregulate murine neural stem/precursor cells. Plos One. 7: e43338. PMID 22952668 DOI: 10.1371/Journal.Pone.0043338  0.29
2010 Hartung HP, Aktas O, Kieseier B, Giancarlo Comi GC. Development of oral cladribine for the treatment of multiple sclerosis. Journal of Neurology. 257: 163-70. PMID 19921304 DOI: 10.1007/s00415-009-5359-0  0.29
2011 Meyer-Schwickerath R, Haug C, Hacker A, Fink F, Seidel D, Hartung HP, Haupts MR. Intracranial venous pressure is normal in patients with multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 17: 637-8. PMID 21228026 DOI: 10.1177/1352458510395982  0.29
2018 Kremer D, Küry P, Hartung HP. ECTRIMS/ACTRIMS 2017: Closing in on neurorepair in progressive multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458518768770. PMID 29629605 DOI: 10.1177/1352458518768770  0.29
2018 Graf J, Jansen L, Ingwersen J, Ringelstein M, Harmel J, Rybak J, Kolbe R, Rhöse L, Gemerzki L, Lee JI, Klistorner A, Guthoff R, Hartung HP, Aktas O, Albrecht P. Multifocal visual evoked potentials in chronic inflammatory demyelinating polyneuropathy. Annals of Clinical and Translational Neurology. 5: 952-961. PMID 30128319 DOI: 10.1002/Acn3.593  0.29
2007 Kieseier BC, Hartung HP, Wiendl H. Immune circuitry in the peripheral nervous system. Current Opinion in Neurology. 19: 437-45. PMID 16969152 DOI: 10.1097/01.Wco.0000245365.51823.72  0.289
2020 Shebl A, Durn BL, Bril V, Merkies ISJ, van NG, Hartung H, Lewis RA, Sobue G, Lawo J, Cornblath DR, Mielke O, Schaik INv. 17. Benefit-Risk Profile of Intravenous Immunoglobulin (IVIG) and Subcutaneous Immunoglobulin (SCIG) in Chronic Inflammatory Demyelinating Polyneuropathy (CIDP): The PATH study Clinical Neurophysiology. 131. DOI: 10.1016/J.Clinph.2019.11.050  0.289
2010 Meyer zu Hörste G, Heidenreich H, Mausberg AK, Lehmann HC, ten Asbroek AL, Saavedra JT, Baas F, Hartung HP, Wiendl H, Kieseier BC. Mouse Schwann cells activate MHC class I and II restricted T-cell responses, but require external peptide processing for MHC class II presentation. Neurobiology of Disease. 37: 483-90. PMID 19914379 DOI: 10.1016/J.Nbd.2009.11.006  0.289
2000 Wohlleben G, Ibrahim SM, Schmidt J, Toyka KV, Hartung HP, Gold R. Regulation of Fas and FasL expression on rat Schwann cells. Glia. 30: 373-81. PMID 10797617 DOI: 10.1002/(SICI)1098-1136(200006)30:4<373::AID-GLIA60>3.0.CO;2-#  0.289
2004 Saleh A, Schroeter M, Jonkmanns C, Hartung HP, Mödder U, Jander S. In vivo MRI of brain inflammation in human ischaemic stroke. Brain : a Journal of Neurology. 127: 1670-7. PMID 15128622 DOI: 10.1093/Brain/Awh191  0.289
2006 Kieseier BC, Hartung HP. Interferon-beta and neuroprotection in multiple sclerosis--facts, hopes and phantasies. Experimental Neurology. 203: 1-4. PMID 17069803 DOI: 10.1016/J.Expneurol.2006.09.007  0.288
2014 Warnke C, Dehmel T, Ramanujam R, Holmen C, Nordin N, Wolfram K, Leussink VI, Hartung HP, Olsson T, Kieseier BC. Initial lymphocyte count and low BMI may affect fingolimod-induced lymphopenia. Neurology. 83: 2153-7. PMID 25361781 DOI: 10.1212/Wnl.0000000000001049  0.288
2019 Graf J, Ingwersen J, Lepka K, Albrecht P, Hartung HP, Ringelstein M, Aktas O. Factors associated with headache in intravenous immunoglobulin treatment for neurological diseases. Acta Neurologica Scandinavica. PMID 31269227 DOI: 10.1111/Ane.13144  0.288
2013 Kieseier BC, Hartung HP. Targeting two-pore domain potassium channels - a promising strategy for treating T cell mediated autoimmunity. Experimental Neurology. 247: 286-8. PMID 23353639 DOI: 10.1016/J.Expneurol.2013.01.016  0.288
2009 Bril V, Katzberg H, Donofrio P, Banach M, Dalakas MC, Deng C, Hanna K, Hartung HP, Hughes RA, Latov N, Merkies IS, van Doorn PA. Electrophysiology in chronic inflammatory demyelinating polyneuropathy with IGIV. Muscle & Nerve. 39: 448-55. PMID 19260050 DOI: 10.1002/Mus.21236  0.288
2002 Hartung HP, Willison HJ, Kieseier BC. Acute immunoinflammatory neuropathy: update on Guillain-Barré syndrome. Current Opinion in Neurology. 15: 571-7. PMID 12352001 DOI: 10.1097/00019052-200210000-00008  0.288
2011 Aktas O, Hartung HP. Beyond axonal transection: Hippocampal damage in multiple sclerosis Annals of Neurology. 69: 433-436. PMID 21446019 DOI: 10.1002/Ana.22409  0.288
2003 Kieseier BC, Hartung HP. Current disease-modifying therapies in multiple sclerosis. Seminars in Neurology. 23: 133-46. PMID 12894379 DOI: 10.1055/s-2003-41138  0.288
2019 Beyer F, Jadasz J, Samper Agrelo I, Schira-Heinen J, Groh J, Manousi A, Bütermann C, Estrada V, Reiche L, Cantone M, Vera J, Viganò F, Dimou L, Müller HW, Hartung HP, et al. Heterogeneous fate choice of genetically modulated adult neural stem cells in gray and white matter of the central nervous system. Glia. PMID 31633850 DOI: 10.1002/Glia.23724  0.287
2007 Hartung H. Book Review McAlpine's Multiple Sclerosis Fourth edition. Edited by Alastair Compston, Christian Confavreux, and Hans Lassmann, with five others. 982 pp., illustrated. Philadelphia, Churchill Livingstone, 2006. $199. 978-0-4430-7271-0 New England Journal of Medicine. 356: 534-535. DOI: 10.1056/Nejmbkrev56924  0.287
2009 Lehmann HC, Köhne A, Bernal F, Jangouk P, Meyer Zu Hörste G, Dehmel T, Hartung HP, Previtali SC, Kieseier BC. Matrix metalloproteinase-2 is involved in myelination of dorsal root ganglia neurons. Glia. 57: 479-89. PMID 18814268 DOI: 10.1002/Glia.20774  0.287
2014 Stettner M, Lohmann B, Wolffram K, Weinberger JP, Dehmel T, Hartung HP, Mausberg AK, Kieseier BC. Interleukin-17 impedes Schwann cell-mediated myelination. Journal of Neuroinflammation. 11: 63. PMID 24678820 DOI: 10.1186/1742-2094-11-63  0.286
2014 Kasper LH, Arnold DL, Coles AJ, Hartung H, Havrdova E, Selmaj KW, Palmer J, Margolin DH, Panzara MA, Compston DAS. Lymphocyte subset dynamics following alemtuzumab treatment in patients who relapsed on a prior therapy Journal of Neuroimmunology. 275: 63-64. DOI: 10.1016/J.Jneuroim.2014.08.167  0.286
2012 Lehmann HC, Macht S, Jander S, Hartung HP, Methner A. Guillain-Barré syndrome variant with prominent facial diplegia, limb paresthesia, and brisk reflexes. Journal of Neurology. 259: 370-1. PMID 21769530 DOI: 10.1007/S00415-011-6169-8  0.286
1988 Hartung HP, Heininger K, Toyka KV. Primary rat astroglial cultures can generate leukotriene B4. Journal of Neuroimmunology. 19: 237-43. PMID 2842377 DOI: 10.1016/0165-5728(88)90005-7  0.286
2012 Heinen A, Tzekova N, Graffmann N, Torres KJ, Uhrberg M, Hartung HP, Küry P. Histone methyltransferase enhancer of zeste homolog 2 regulates Schwann cell differentiation. Glia. 60: 1696-708. PMID 22821416 DOI: 10.1002/Glia.22388  0.286
2011 Hughes R, Hartung HP. Neuroimmunology: Assessing the value of plasma exchange in neurology. Nature Reviews. Neurology. 7: 309-10. PMID 21537357 DOI: 10.1038/Nrneurol.2011.59  0.285
1990 Schmidt B, Stoll G, Toyka KV, Hartung HP. Rat astrocytes express interferon-gamma immunoreactivity in normal optic nerve and after nerve transection. Brain Research. 515: 347-50. PMID 2113417 DOI: 10.1016/0006-8993(90)90621-H  0.285
2017 Malviya M, Barman S, Golombeck KS, Planagumà J, Mannara F, Strutz-Seebohm N, Wrzos C, Demir F, Baksmeier C, Steckel J, Falk KK, Gross CC, Kovac S, Bönte K, Johnen A, ... ... Hartung HP, et al. NMDAR encephalitis: passive transfer from man to mouse by a recombinant antibody. Annals of Clinical and Translational Neurology. 4: 768-783. PMID 29159189 DOI: 10.1002/Acn3.444  0.285
1996 Hartung H, Kieseier BC. Targets For The Therapeutic Action Of Interferon-Beta In Multiple Sclerosis Annals of Neurology. 40: 825-826. PMID 9007085 DOI: 10.1002/Ana.410400602  0.284
2015 Kremer D, Hartung HP, Stangel M, Küry P. New therapeutic strategies for remyelination in multiple sclerosis | Neue Therapiestrategien zur Myelinreparatur bei der Multiplen Sklerose Nervenarzt. 86: 934-946. PMID 26122637 DOI: 10.1007/s00115-014-4249-6  0.284
2015 Schröder K, Finis D, Harmel J, Ringelstein M, Hartung HP, Geerling G, Aktas O, Guthoff R. Acetazolamide therapy in a case of fingolimod-associated macular edema: early benefits and long-term limitations. Multiple Sclerosis and Related Disorders. 4: 406-8. PMID 26346788 DOI: 10.1016/J.Msard.2015.06.015  0.284
2020 Heitmann H, Haller B, Tiemann L, Mühlau M, Berthele A, Tölle TR, Salmen A, Ambrosius B, Bayas A, Asseyer S, Hartung HP, Heesen C, Stangel M, Wildemann B, Haars S, et al. Longitudinal prevalence and determinants of pain in multiple sclerosis: results from the German National Multiple Sclerosis Cohort study. Pain. 161: 787-796. PMID 32197038 DOI: 10.1097/J.Pain.0000000000001767  0.283
2009 Hofstetter HH, Smolianov V, Hartung HP. Untired regulatory T cells: untying fatigue from T cell regulation in multiple sclerosis. European Neurology. 62: 327-9. PMID 19752559 DOI: 10.1159/000236376  0.283
2004 Küry P, Zickler P, Stoll G, Hartung HP, Jander S. Osteopontin, a macrophage-derived matricellular glycoprotein, inhibits axon outgrowth. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 398-400. PMID 15625076 DOI: 10.1096/Fj.04-1777Fje  0.283
2015 Meyer Zu Horste G, Derksen A, Stassart R, Szepanowski F, Thanos M, Stettner M, Boettcher C, Lehmann HC, Hartung HP, Kieseier BC. Neuronal ADAM10 Promotes Outgrowth of Small-Caliber Myelinated Axons in the Peripheral Nervous System. Journal of Neuropathology and Experimental Neurology. 74: 1077-85. PMID 26426268 DOI: 10.1097/Nen.0000000000000253  0.283
2016 Weber A, Zimmermann C, Mausberg AK, Dehmel T, Kieseier BC, Hartung HP, Hofstetter HH. Pseudomonas aeruginosa and its bacterial components influence the cytokine response in thymocytes and splenocytes. Infection and Immunity. PMID 26902726 DOI: 10.1128/Iai.00905-15  0.282
2017 Jadasz JJ, Tepe L, Beyer F, Samper Agrelo I, Akkermann R, Spitzhorn LS, Silva ME, Oreffo ROC, Hartung HP, Prigione A, Rivera FJ, Adjaye J, Küry P. Human mesenchymal factors induce rat hippocampal- and human neural stem cell dependent oligodendrogenesis. Glia. PMID 28940767 DOI: 10.1002/Glia.23233  0.282
2012 Hartung HP. Advances in the management of multiple sclerosis-related spasticity Expert Review of Neurotherapeutics. 12: 1. PMID 22509984 DOI: 10.1586/Ern.12.10  0.281
2014 Ringelstein M, Kleiter I, Ayzenberg I, Borisow N, Paul F, Ruprecht K, Kraemer M, Cohn E, Wildemann B, Jarius S, Hartung HP, Aktas O, Albrecht P. Visual evoked potentials in neuromyelitis optica and its spectrum disorders. Multiple Sclerosis (Houndmills, Basingstoke, England). 20: 617-20. PMID 24009163 DOI: 10.1177/1352458513503053  0.281
2007 Lehmann HC, Hartung HP, Hetzel GR, Kieseier BC. [Plasma exchange as a therapeutic option in neurological disorders]. Der Nervenarzt. 78: 166, 168-70, 172-6. PMID 17268791 DOI: 10.1007/S00115-006-2229-1  0.28
2012 Gliem M, Mausberg AK, Lee JI, Simiantonakis I, Van Rooijen N, Hartung HP, Jander S. Macrophages prevent hemorrhagic infarct transformation in murine stroke models Annals of Neurology. 71: 743-752. PMID 22718543 DOI: 10.1002/Ana.23529  0.28
2008 Lehmann HC, Hartung HP. Complementing the therapeutic armamentarium for Miller Fisher Syndrome and related immune neuropathies. Brain : a Journal of Neurology. 131: 1168-70. PMID 18450786 DOI: 10.1093/Brain/Awn072  0.28
2019 Warnke C, Hartung HP. Big data in MS-What can we learn from large international observational studies such as MSBase? Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458519868982. PMID 31397200 DOI: 10.1177/1352458519868982  0.279
2011 Hartung H, Matthews V, Ross AP, Pitschnau-Michel D, Thalheim C, Ward-Abel N. Disparities in nursing of multiple sclerosis patients-results of a European nurse survey European Neurological Review. 6: 106. DOI: 10.17925/Enr.2011.06.02.106  0.279
2020 Lewis RA, Cornblath DR, Hartung HP, Sobue G, Lawo JP, Mielke O, Durn BL, Bril V, Merkies ISJ, Bassett P, Cleasby A, van Schaik IN. Placebo Effect in Chronic Inflammatory Demyelinating Polyneuropathy: The PATH study and a systematic review. Journal of the Peripheral Nervous System : Jpns. PMID 32627277 DOI: 10.1111/Jns.12402  0.278
2009 Kieseier BC, Wiendl H, Hartung HP, Stüve O. The future of multiple sclerosis therapy. Pharmacological Research. 60: 207-11. PMID 19717009 DOI: 10.1016/j.phrs.2009.03.016  0.277
2015 Ingwersen J, Menge T, Wingerath B, Kaya D, Graf J, Prozorovski T, Keller A, Backes C, Beier M, Scheffler M, Dehmel T, Kieseier BC, Hartung HP, Küry P, Aktas O. Natalizumab restores aberrant miRNA expression profile in multiple sclerosis and reveals a critical role for miR-20b. Annals of Clinical and Translational Neurology. 2: 43-55. PMID 25642434 DOI: 10.1002/Acn3.152  0.277
2017 Warnke C, Graf J, Hartung HP. Reconstitution of the peripheral immune repertoire following withdrawal of fingolimod. Multiple Sclerosis (Houndmills, Basingstoke, England). 23: 1176-1178. PMID 28749310 DOI: 10.1177/1352458517720045  0.277
2001 Hartung H, Kieseier BC, Kiefer R. Progress in Guillain-Barré syndrome Current Opinion in Neurology. 14: 597-604. PMID 11562571 DOI: 10.1097/00019052-200110000-00008  0.277
2019 Mielke O, Bril V, Cornblath DR, Lawo JP, van Geloven N, Hartung HP, Lewis RA, Merkies ISJ, Sobue G, Durn B, Shebl A, van Schaik IN. Restabilization treatment after IVIG withdrawal in chronic inflammatory demyelinating polyneuropathy. Results from the pre-randomization phase of the Polyneuropathy and Treatment with Hizentra® (PATH) study. Journal of the Peripheral Nervous System : Jpns. PMID 30672067 DOI: 10.1111/Jns.12303  0.277
2014 Hartung HP, Kieseier BC. The new therapeutic landscape in multiple sclerosis: exciting times and new perspectives. Current Opinion in Neurology. 27: 243-5. PMID 24751962 DOI: 10.1097/Wco.0000000000000101  0.277
2011 Buck D, Cepok S, Hoffmann S, Grummel V, Jochim A, Berthele A, Hartung HP, Wassmuth R, Hemmer B. Influence of the HLA-DRB1 genotype on antibody development to interferon beta in multiple sclerosis. Archives of Neurology. 68: 480-7. PMID 21482927 DOI: 10.1001/Archneurol.2011.65  0.276
2012 Hartung H, Dihné M. Volume Transmission–Mediated Encephalopathies: A Possible New Concept? Jama Neurology. 69: 315-321. PMID 22410441 DOI: 10.1001/Archneurol.2011.933  0.276
2007 Zipp F, Waiczies S, Aktas O, Neuhaus O, Hemmer B, Schraven B, Nitsch R, Hartung HP. Impact of HMG-CoA reductase inhibition on brain pathology. Trends in Pharmacological Sciences. 28: 342-9. PMID 17573124 DOI: 10.1016/J.Tips.2007.05.001  0.276
2009 Moraal B, Pohl C, Uitdehaag BM, Polman CH, Edan G, Freedman MS, Hartung HP, Kappos L, Miller DH, Montalban X, Lanius V, Sandbrink R, Barkhof F. Magnetic resonance imaging predictors of conversion to multiple sclerosis in the BENEFIT study. Archives of Neurology. 66: 1345-52. PMID 19901165 DOI: 10.1001/Archneurol.2009.243  0.275
1993 Jung S, Schluesener HJ, Toyka KV, Hartung HP. Modulation of EAE by vaccination with T cell receptor peptides: V beta 8 T cell receptor peptide-specific CD4+ lymphocytes lack direct immunoregulatory activity. Journal of Neuroimmunology. 45: 15-22. PMID 8101189 DOI: 10.1016/0165-5728(93)90158-U  0.275
1989 Hartung HP, Schäfer B, Heininger K, Toyka KV. Recombinant interleukin-1 beta stimulates eicosanoid production in rat primary culture astrocytes. Brain Research. 489: 113-9. PMID 2501001 DOI: 10.1016/0006-8993(89)90013-9  0.275
2010 Meyer Zu Hörste G, Zozulya AL, El-Haddad H, Lehmann HC, Hartung HP, Wiendl H, Kieseier BC. Active immunization induces toxicity of diphtheria toxin in diphtheria resistant mice--implications for neuroinflammatory models. Journal of Immunological Methods. 354: 80-4. PMID 20138048 DOI: 10.1016/J.Jim.2010.01.012  0.275
1987 Heininger K, Fierz W, Schäfer B, Hartung H, Toyka KV. Adoptive transfer experimental autoimmune encephalitis: evidence for central and peripheral nerve dysfunction Journal of Neuroimmunology. 16: 76. DOI: 10.1016/0165-5728(87)90244-X  0.275
2000 Fazekas F, Strasser-Fuchs S, Schmidt H, Enzinger C, Ropele S, Lechner A, Flooh E, Schmidt R, Hartung H. Apolipoprotein E genotype related differences in brain lesions of multiple sclerosis Journal of Neurology, Neurosurgery, and Psychiatry. 69: 25-28. PMID 10864599 DOI: 10.1136/Jnnp.69.1.25  0.275
2020 Cortese M, Munger KL, Martínez-Lapiscina EH, Barro C, Edan G, Freedman MS, Hartung HP, Montalbán X, Foley FW, Penner IK, Hemmer B, Fox EJ, Schippling S, Wicklein EM, Kappos L, et al. Vitamin D, smoking, EBV, and long-term cognitive performance in MS: 11-year follow-up of BENEFIT. Neurology. PMID 32300060 DOI: 10.1212/Wnl.0000000000009371  0.275
2017 Szepanowski F, Donaldson DM, Hartung HP, Mausberg AK, Kleinschnitz C, Kieseier BC, Stettner M. Dimethyl fumarate accelerates peripheral nerve regeneration via activation of the anti-inflammatory and cytoprotective Nrf2/HO-1 signaling pathway. Acta Neuropathologica. PMID 28108787 DOI: 10.1007/S00401-017-1676-Z  0.274
2013 Kremer D, Schichel T, Förster M, Tzekova N, Bernard C, van der Valk P, van Horssen J, Hartung HP, Perron H, Küry P. Human endogenous retrovirus type W envelope protein inhibits oligodendroglial precursor cell differentiation. Annals of Neurology. 74: 721-32. PMID 23836485 DOI: 10.1002/Ana.23970  0.273
1993 Seeldrayers PA, Syha J, Morrissey SP, Stodal H, Vass K, Jung S, Gneiting T, Lassmann H, Haase A, Hartung HP, Toyka KV. Magnetic resonance imaging investigation of blood-brain barrier damage in adoptive transfer experimental autoimmune encephalomyelitis Journal of Neuroimmunology. 46: 199-206. PMID 8360329 DOI: 10.1016/0165-5728(93)90250-3  0.273
2023 Göttle P, Groh J, Reiche L, Gruchot J, Rychlik N, Werner L, Samper Agrelo I, Akkermann R, Zink A, Prigione A, Hartung HP, Martini R, Küry P. Teriflunomide as a therapeutic means for myelin repair. Journal of Neuroinflammation. 20: 7. PMID 36611185 DOI: 10.1186/s12974-022-02686-6  0.273
2014 Winter M, Baksmeier C, Hartung H, Goebels N. Dose dependent inhibition of immune mediated demyelination by IVIG Journal of Neuroimmunology. 275: 60-61. DOI: 10.1016/J.Jneuroim.2014.08.159  0.272
2019 Aktas O, Hartung HP. CSI: MS. Tracing optic nerve involvement by standardized optical coherence tomography. Annals of Neurology. PMID 30900764 DOI: 10.1002/Ana.25471  0.272
1997 Zettl UK, Mix E, Zielasek J, Stangel M, Hartung H, Gold R. Apoptosis of Myelin-Reactive T Cells Induced by Reactive Oxygen and Nitrogen Intermediatesin Vitro Cellular Immunology. 178: 1-8. PMID 9184692 DOI: 10.1006/Cimm.1997.1113  0.272
2005 Neuhaus O, Stüve O, Zamvil SS, Hartung HP. Evaluation of HMG-CoA reductase inhibitors for multiple sclerosis: opportunities and obstacles. Cns Drugs. 19: 833-41. PMID 16185093 DOI: 10.2165/00023210-200519100-00003  0.272
1999 Schneider C, Dalakas MC, Toyka KV, Said G, Hartung H, Gold R. T-Cell Apoptosis in Inflammatory Neuromuscular Disorders Associated With Human Immunodeficiency Virus Infection Jama Neurology. 56: 79-83. PMID 9923764 DOI: 10.1001/Archneur.56.1.79  0.272
2011 Walter J, Honsek SD, Illes S, Wellen JM, Hartung HP, Rose CR, Dihné M. A new role for interferon gamma in neural stem/precursor cell dysregulation. Molecular Neurodegeneration. 6: 18. PMID 21371330 DOI: 10.1186/1750-1326-6-18  0.272
2010 Lehmann HC, Jangouk P, Kierysch EK, Meyer zu Hörste G, Hartung HP, Kieseier BC. Autoantibody-mediated dysfunction of sympathetic neurons in guillain-barre syndrome. Archives of Neurology. 67: 203-10. PMID 20142528 DOI: 10.1001/Archneurol.2009.331  0.272
1999 Roob G, Fazekas F, Hartung H. Peripheral Facial Palsy: Etiology, Diagnosis and Treatment European Neurology. 41: 3-9. PMID 9885321 DOI: 10.1159/000007990  0.271
2019 Göttle P, Förster M, Weyers V, Küry P, Rejdak K, Hartung HP, Kremer D. An unmet clinical need: roads to remyelination in MS. Neurological Research and Practice. 1: 21. PMID 33324887 DOI: 10.1186/s42466-019-0026-0  0.271
2012 Stuve O, Selmaj K, Li D, Hartung H, Hemmer B, Kappos L, Freedman M, Rieckmann P, Montalban X, Zhang Auberson L, Pohlmann H, Mercier F, Dahlke F, Wallstrom E. BAF312, a Selective Sphingosine-1-Phosphate Receptor Modulator Improves MRI and Clinical Outcomes in Relapsing-Remitting Multiple Sclerosis (RRMS) (S30.001) Neurology. 78: S30.001-S30.001. DOI: 10.1212/Wnl.78.1_Meetingabstracts.S30.001  0.271
1998 Kieseier BC, Kiefer R, Clements JM, Miller K, Wells GM, Schweitzer T, Gearing AJ, Hartung HP. Matrix metalloproteinase-9 and -7 are regulated in experimental autoimmune encephalomyelitis. Brain : a Journal of Neurology. 121: 159-66. PMID 9549496 DOI: 10.1093/Brain/121.1.159  0.271
2023 Hartung HP, Cree BAC, Barnett M, Meuth SG, Bar-Or A, Steinman L. Bioavailable central nervous system disease-modifying therapies for multiple sclerosis. Frontiers in Immunology. 14: 1290666. PMID 38162670 DOI: 10.3389/fimmu.2023.1290666  0.271
1999 Mix E, Zettl UK, Zielasek J, Hartung HP, Gold R. Apoptosis induction by macrophage-derived reactive oxygen species in myelin-specific T cells requires cell-cell contact. Journal of Neuroimmunology. 95: 152-6. PMID 10229125 DOI: 10.1016/S0165-5728(99)00006-5  0.271
2008 Lehmann HC, Hartung HP, Meyer Zu Hörste G, Kieseier BC. Plasma exchange in immune-mediated neuropathies. Current Opinion in Neurology. 21: 547-54. PMID 18769248 DOI: 10.1097/Wco.0B013E32830B0F61  0.27
2009 Nolting T, Lindecke A, Koutsilieri E, Maschke M, Husstedt I, Sopper S, Stüve O, Hartung H, Arendt G. Measurement of soluble inflammatory mediators in cerebrospinal fluid of human immunodeficiency virus-positive patients at distinct stages of infection by solid-phase protein array. Journal of Neurovirology. 15: 390-400. PMID 20001608 DOI: 10.3109/13550280903350192  0.27
2012 Albrecht P, Bouchachia I, Goebels N, Henke N, Hofstetter HH, Issberner A, Kovacs Z, Lewerenz J, Lisak D, Maher P, Mausberg AK, Quasthoff K, Zimmermann C, Hartung HP, Methner A. Effects of dimethyl fumarate on neuroprotection and immunomodulation. Journal of Neuroinflammation. 9: 163. PMID 22769044 DOI: 10.1186/1742-2094-9-163  0.27
2007 Habisch H, Schwalenstöcker B, Danzeisen R, Neuhaus O, Hartung H, Ludolph A. Limited effects of glatiramer acetate in the high-copy number hSOD1-G93A mouse model of ALS. Experimental Neurology. 206: 288-295. PMID 17597611 DOI: 10.1016/J.Expneurol.2007.05.007  0.27
1989 Hartung HP. Activation of macrophages by neuropeptides. Brain, Behavior, and Immunity. 2: 275-81. PMID 3076476 DOI: 10.1016/0889-1591(88)90029-3  0.27
2010 Merkies IS, Hughes RA, Donofrio P, Bril V, Dalakas MC, Hanna K, Hartung HP, Latov N, van Doorn PA, Deng C. Understanding the consequences of chronic inflammatory demyelinating polyradiculoneuropathy from impairments to activity and participation restrictions and reduced quality of life: the ICE study. Journal of the Peripheral Nervous System : Jpns. 15: 208-15. PMID 21040143 DOI: 10.1111/J.1529-8027.2010.00274.X  0.27
1983 Hartung H. Acetyl glyceryl ether phosphorylcholine (platelet-activating factor) mediates heightened metabolic activity in macrophages Febs Letters. 160: 209-212. PMID 6309563 DOI: 10.1016/0014-5793(83)80968-5  0.269
2019 Amedonu E, Brenker C, Barman S, Schreiber JA, Becker S, Peischard S, Strutz-Seebohm N, Strippel C, Dik A, Hartung HP, Budde T, Wiendl H, Strünker T, Wünsch B, Goebels N, et al. An Assay to Determine Mechanisms of Rapid Autoantibody-Induced Neurotransmitter Receptor Endocytosis and Vesicular Trafficking in Autoimmune Encephalitis. Frontiers in Neurology. 10: 178. PMID 30881339 DOI: 10.3389/Fneur.2019.00178  0.269
2000 Auer-Grumbach M, Löscher WN, Wagner K, Petek E, Körner E, Offenbacher H, Hartung H. Phenotypic and genotypic heterogeneity in hereditary motor neuronopathy type V: a clinical, electrophysiological and genetic study. Brain. 123: 1612-1623. PMID 10908191 DOI: 10.1093/Brain/123.8.1612  0.269
2008 Heinen A, Kremer D, Hartung HP, Küry P. p57 kip2's role beyond Schwann cell cycle control. Cell Cycle (Georgetown, Tex.). 7: 2781-6. PMID 18769142 DOI: 10.4161/Cc.7.18.6629  0.269
1997 Stangel M, Hartung H, Marx P, Gold R. Side effects of high-dose intravenous immunoglobulins. Clinical Neuropharmacology. 20: 385-393. PMID 9331514 DOI: 10.1097/00002826-199710000-00002  0.268
1996 Schneider C, Gold R, Dalakas MC, Schmied M, Lassmann H, Toyka KV, Hartung H. MHC class I-mediated cytotoxicity does not induce apoptosis in muscle fibers nor in inflammatory T cells: studies in patients with polymyositis, dermatomyositis, and inclusion body myositis. Journal of Neuropathology and Experimental Neurology. 55: 1205-1209. PMID 8957443 DOI: 10.1097/00005072-199612000-00003  0.268
2008 Menge T, Weber MS, Hemmer B, Kieseier BC, von Büdingen HC, Warnke C, Zamvil SS, Boster A, Khan O, Hartung HP, Stüve O. Disease-modifying agents for multiple sclerosis: recent advances and future prospects. Drugs. 68: 2445-68. PMID 19016573 DOI: 10.2165/0003495-200868170-00004  0.268
2006 Cepok S, Geldern Gv, Grummel V, Hochgesand S, Celik H, Hartung H, Hemmer B. Accumulation of class switched IgD−IgM− memory B cells in the cerebrospinal fluid during neuroinflammation Journal of Neuroimmunology. 180: 33-39. PMID 16952404 DOI: 10.1016/J.Jneuroim.2006.06.031  0.268
2021 Graf J, Mares J, Barnett M, Aktas O, Albrecht P, Zamvil SS, Hartung HP. Targeting B cells to modify MS, NMOSD, and MOGAD: Part 2. Neurology(R) Neuroimmunology & Neuroinflammation. 8. PMID 33411674 DOI: 10.1212/NXI.0000000000000919  0.268
2011 Saure C, Warnke C, Zohren F, Schroeder T, Bruns I, Cadeddu RP, Weigelt C, Fischer U, Kobbe G, Hartung HP, Adams O, Kieseier BC, Haas R. Natalizumab and impedance of the homing of CD34+ hematopoietic progenitors. Archives of Neurology. 68: 1428-31. PMID 22084125 DOI: 10.1001/Archneurol.2011.238  0.268
2022 Querol LA, Hartung HP, Lewis RA, van Doorn PA, Hammond TR, Atassi N, Alonso-Alonso M, Dalakas MC. The Role of the Complement System in Chronic Inflammatory Demyelinating Polyneuropathy: Implications for Complement-Targeted Therapies. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 35378684 DOI: 10.1007/s13311-022-01221-y  0.268
2005 Frohman EM, Filippi M, Stuve O, Waxman SG, Corboy J, Phillips JT, Lucchinetti C, Wilken J, Karandikar N, Hemmer B, Monson N, De Keyser J, Hartung H, Steinman L, Oksenberg JR, et al. Characterizing the mechanisms of progression in multiple sclerosis: evidence and new hypotheses for future directions. Archives of Neurology. 62: 1345-56. PMID 16157741 DOI: 10.1001/Archneur.62.9.1345  0.267
2005 Auer-Grumbach M, Schlotter-Weigel B, Lochmüller H, Strobl-Wildemann G, Auer-Grumbach P, Fischer R, Offenbacher H, Zwick EB, Robl T, Hartl G, Hartung HP, Wagner K, Windpassinger C. Phenotypes of the N88S Berardinelli-Seip congenital lipodystrophy 2 mutation. Annals of Neurology. 57: 415-24. PMID 15732094 DOI: 10.1002/Ana.20410  0.267
1995 Hartung H, Reiners K, Archelos JJ, Michels M, Seeldrayers P, Heidenreich F, Pflughaupt KW, Toyka KV. Circulating adhesion molecules and tumor necrosis factor receptor in multiple sclerosis: correlation with magnetic resonance imaging. Annals of Neurology. 38: 186-193. PMID 7544573 DOI: 10.1002/Ana.410380210  0.266
2017 Ingenhoven K, Kramer D, Jensen PE, Hermanrud C, Ryner M, Deisenhammer F, Pallardy M, Menge T, Hartung HP, Kieseier BC, Bertotti E, Creeke P, Fogdell-Hahn A, Warnke C. Development and Validation of an Enzyme-Linked Immunosorbent Assay for the Detection of Binding Anti-Drug Antibodies against Interferon Beta. Frontiers in Neurology. 8: 305. PMID 28729851 DOI: 10.3389/Fneur.2017.00305  0.266
2014 Ringelstein M, Albrecht P, Südmeyer M, Harmel J, Müller AK, Keser N, Finis D, Ferrea S, Guthoff R, Schnitzler A, Hartung HP, Methner A, Aktas O. Subtle retinal pathology in amyotrophic lateral sclerosis. Annals of Clinical and Translational Neurology. 1: 290-7. PMID 25590041 DOI: 10.1002/Acn3.46  0.266
2022 Bierhansl L, Hartung HP, Aktas O, Ruck T, Roden M, Meuth SG. Thinking outside the box: non-canonical targets in multiple sclerosis. Nature Reviews. Drug Discovery. PMID 35668103 DOI: 10.1038/s41573-022-00477-5  0.265
2018 Cohen JA, Comi G, Arnold DL, Bar-Or A, Selmaj KW, Steinman L, Havrdová EK, Cree BA, Montalbán X, Hartung HP, Huang V, Frohna P, Skolnick BE, Kappos L. Efficacy and safety of ozanimod in multiple sclerosis: Dose-blinded extension of a randomized phase II study. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458518789884. PMID 30043658 DOI: 10.1177/1352458518789884  0.265
2009 Warnke C, Meyer zu Hörste G, Hartung HP, Stüve O, Kieseier BC. Review of teriflunomide and its potential in the treatment of multiple sclerosis. Neuropsychiatric Disease and Treatment. 5: 333-40. PMID 19557143  0.265
2000 Auer-Grumbach M, Wagner K, Strasser-Fuchs S, Md WNL, Fazekas F, Millner M, Hartung H. Clinical predominance of proximal upper limb weakness in CMT1A syndrome. Muscle & Nerve. 23: 1243-1249. PMID 10918262 DOI: 10.1002/1097-4598(200008)23:8<1243::Aid-Mus13>3.0.Co;2-Z  0.264
2015 Kleiter I, Gahlen A, Borisow N, Fischer K, Wernecke KD, Wegner B, Hellwig K, Pache F, Ruprecht K, Havla J, Krumbholz M, Kümpfel T, Aktas O, Hartung HP, Ringelstein M, et al. Neuromyelitis optica: Evaluation of 871 attacks and 1153 treatment courses. Annals of Neurology. PMID 26537743 DOI: 10.1002/Ana.24554  0.264
2006 Köller H, Schroeter M, Feischen H, Hartung HP, Kieseier BC. Subcutaneous self-infusions of immunoglobulins as a potential therapeutic regimen in immune-mediated neuropathies. Journal of Neurology. 253: 1505-6. PMID 16972122 DOI: 10.1007/S00415-006-0258-0  0.264
2017 Plavina T, Muralidharan KK, Kuesters G, Mikol D, Evans K, Subramanyam M, Nestorov I, Chen Y, Dong Q, Ho PR, Amarante D, Adams A, De Sèze J, Fox R, Gold R, ... ... Hartung HP, et al. Reversibility of the effects of natalizumab on peripheral immune cell dynamics in MS patients. Neurology. PMID 28916537 DOI: 10.1212/Wnl.0000000000004485  0.263
2012 Perron H, Germi R, Bernard C, Garcia-Montojo M, Deluen C, Farinelli L, Faucard R, Veas F, Stefas I, Fabriek BO, Van-Horssen J, Van-der-Valk P, Gerdil C, Mancuso R, Saresella M, ... ... Hartung HP, et al. Human endogenous retrovirus type W envelope expression in blood and brain cells provides new insights into multiple sclerosis disease. Multiple Sclerosis (Houndmills, Basingstoke, England). 18: 1721-36. PMID 22457345 DOI: 10.1177/1352458512441381  0.263
2004 Köller H, Kornischka J, Neuen-Jacob E, Saleh A, von Giesen HJ, Schmiedel J, Reichmann H, Hartung HP. Persistent organic personality change as rare psychiatric manifestation of MELAS syndrome. Journal of Neurology. 250: 1501-2. PMID 14673589 DOI: 10.1007/S00415-003-0260-8  0.263
1999 Kieseier BC, Paul R, Koedel U, Seifert T, Clements JM, Gearing AJH, Pfister H, Hartung H. Differential expression of matrix metalloproteinases in bacterial meningitis. Brain. 122: 1579-1587. PMID 10430840 DOI: 10.1093/Brain/122.8.1579  0.263
2023 Vališ M, Achiron A, Hartung HP, Mareš J, Tichá V, Štourač P, Halusková S, Angelucci F, Pavelek Z. The Benefits and Risks of Switching from Fingolimod to Siponimod for the Treatment of Relapsing-Remitting and Secondary Progressive Multiple Sclerosis. Drugs in R&D. PMID 37640862 DOI: 10.1007/s40268-023-00434-6  0.262
2019 Neuhaus O, Wiesmüller KH, Hartung HP, Wiendl H. Prominent T-Cell Responses against the Acetylcholine Receptor Subunit in Myasthenia Gravis. Neurology Research International. 2019: 1969068. PMID 30941215 DOI: 10.1155/2019/1969068  0.262
2017 Albrecht P, Blasberg C, Ringelstein M, Müller AK, Finis D, Guthoff R, Kadas EM, Lagreze W, Aktas O, Hartung HP, Paul F, Brandt AU, Methner A. Optical coherence tomography for the diagnosis and monitoring of idiopathic intracranial hypertension. Journal of Neurology. PMID 28584914 DOI: 10.1007/S00415-017-8532-X  0.262
1993 Zielasek J, Archelos JJ, Toyka KV, Hartung HP. Expression of intercellular adhesion molecule-1 on rat microglial cells. Neuroscience Letters. 153: 136-9. PMID 8100989 DOI: 10.1016/0304-3940(93)90306-6  0.262
2013 Oberwahrenbrock T, Ringelstein M, Jentschke S, Deuschle K, Klumbies K, Bellmann-Strobl J, Harmel J, Ruprecht K, Schippling S, Hartung HP, Aktas O, Brandt AU, Paul F. Retinal ganglion cell and inner plexiform layer thinning in clinically isolated syndrome. Multiple Sclerosis (Houndmills, Basingstoke, England). 19: 1887-95. PMID 23702433 DOI: 10.1177/1352458513489757  0.261
2013 Warnke C, Meyer Zu Hörste G, Menge T, Stüve O, Hartung HP, Wiendl H, Kieseier BC. Teriflunomide for treatment of multiple sclerosis | Teriflunomid zur Behandlung der Multiplen Sklerose Nervenarzt. 84: 724-731. PMID 23695001 DOI: 10.1007/S00115-013-3779-7  0.261
2006 Zhou D, Srivastava R, Grummel V, Cepok S, Hartung HP, Hemmer B. High throughput analysis of TCR-beta rearrangement and gene expression in single T cells. Laboratory Investigation; a Journal of Technical Methods and Pathology. 86: 314-21. PMID 16446708 DOI: 10.1038/Labinvest.3700381  0.261
2019 Förster M, Graf J, Mares J, Aktas O, Hartung HP, Kremer D. Drug Treatment of Clinically Isolated Syndrome. Cns Drugs. 33: 659-676. PMID 31290079 DOI: 10.1007/s40263-019-00647-x  0.261
2012 Deng C, Hanna K, Bril V, Dalakas MC, Donofrio P, van Doorn PA, Hartung HP, Merkies IS. Challenges of clinical trial design when there is lack of clinical equipoise: use of a response-conditional crossover design. Journal of Neurology. 259: 348-52. PMID 21822934 DOI: 10.1007/S00415-011-6200-0  0.261
2015 Gliem M, Krammes K, Liaw L, van Rooijen N, Hartung HP, Jander S. Macrophage-derived osteopontin induces reactive astrocyte polarization and promotes re-establishment of the blood brain barrier after ischemic stroke. Glia. 63: 2198-207. PMID 26148976 DOI: 10.1002/Glia.22885  0.261
1996 Gold R, Zielasek J, Schröder JM, Sellhaus B, Cedarbaum J, Hartung HP, Sendtner M, Toyka KV. Treatment with ciliary neurotrophic factor does not improve regeneration in experimental autoimmune neuritis of the Lewis rat. Muscle & Nerve. 19: 1177-80. PMID 8761279 DOI: 10.1002/(Sici)1097-4598(199609)19:9<1177::Aid-Mus17>3.0.Co;2-S  0.26
2010 Zickler P, Küry P, Gliem M, Hartung HP, Jander S. Differential patterns of local gene regulation in crush lesions of the rat optic and sciatic nerve: relevance to posttraumatic regeneration. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 26: 483-94. PMID 20798533 DOI: 10.1159/000320571  0.259
2005 Rice GP, Hartung HP, Calabresi PA. Anti-alpha4 integrin therapy for multiple sclerosis: mechanisms and rationale. Neurology. 64: 1336-42. PMID 15851719 DOI: 10.1212/01.Wnl.0000158329.30470.D0  0.259
1995 Zielasek J, Reichmann H, Künzig H, Jung S, Hartung H, Toyka KV. Inhibition of brain macrophage/microglial respiratory chain enzyme activity in experimental autoimmune encephalomyelitis of the Lewis rat. Neuroscience Letters. 184: 129-132. PMID 7724046 DOI: 10.1016/0304-3940(94)11187-N  0.259
2002 Willison H, Stoll G, Toyka KV, Berger T, Hartung HP. Autoimmunity and inflammation in the peripheral nervous system. Trends in Neurosciences. 25: 127-9. PMID 11852137 DOI: 10.1016/S0166-2236(00)02120-2  0.259
2003 Auer-Grumbach M, De Jonghe P, Verhoeven K, Timmerman V, Wagner K, Hartung HP, Nicholson GA. Autosomal dominant inherited neuropathies with prominent sensory loss and mutilations: a review. Archives of Neurology. 60: 329-34. PMID 12633143 DOI: 10.1001/Archneur.60.3.329  0.259
2014 Menge T, Stüve O, Kieseier BC, Hartung HP. Alemtuzumab: the advantages and challenges of a novel therapy in MS. Neurology. 83: 87-97. PMID 24920854 DOI: 10.1212/Wnl.0000000000000540  0.259
2017 Stellmann JP, Krumbholz M, Friede T, Gahlen A, Borisow N, Fischer K, Hellwig K, Pache F, Ruprecht K, Havla J, Kümpfel T, Aktas O, Hartung HP, Ringelstein M, Geis C, et al. Immunotherapies in neuromyelitis optica spectrum disorder: efficacy and predictors of response. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 28572277 DOI: 10.1136/Jnnp-2017-315603  0.259
2017 Kremer D, Glanzman R, Traboulsee A, Nath A, Groc L, Horwitz M, Göttle P, Perron H, Gold J, Hartung HP, Küry P. Prehistoric enemies within: The contribution of human endogenous retroviruses to neurological diseases. Meeting report: "Second International Workshop on Human Endogenous Retroviruses and Disease", Washington DC, March 13th and 14th 2017. Multiple Sclerosis and Related Disorders. 15: 18-23. PMID 28641767 DOI: 10.1016/J.Msard.2017.05.001  0.259
2020 Hecker C, Dietrich M, Issberner A, Hartung HP, Albrecht P. Comparison of different optomotor response readouts for visual testing in experimental autoimmune encephalomyelitis-optic neuritis. Journal of Neuroinflammation. 17: 216. PMID 32682447 DOI: 10.1186/S12974-020-01889-Z  0.258
2016 Reich K, Hartung HP, Lebwohl M. More on PML in Patients Treated with Dimethyl Fumarate. The New England Journal of Medicine. 374: 294-5. PMID 26789900 DOI: 10.1056/Nejmc1512228#Sa1  0.258
1987 Hartung HP, Toyka KV. Phorbol diester TPA elicits prostaglandin E release from cultured rat astrocytes. Brain Research. 417: 347-9. PMID 3498530 DOI: 10.1016/0006-8993(87)90461-6  0.258
2007 Saleh A, Schroeter M, Ringelstein A, Hartung HP, Siebler M, Mödder U, Jander S. Iron oxide particle-enhanced MRI suggests variability of brain inflammation at early stages after ischemic stroke. Stroke; a Journal of Cerebral Circulation. 38: 2733-7. PMID 17717318 DOI: 10.1161/Strokeaha.107.481788  0.257
2012 Jadasz JJ, Rivera FJ, Taubert A, Kandasamy M, Sandner B, Weidner N, Aktas O, Hartung HP, Aigner L, Küry P. p57kip2 regulates glial fate decision in adult neural stem cells Development (Cambridge). 139: 3306-3315. PMID 22874918 DOI: 10.1242/Dev.074518  0.257
2018 Lee J, Jansen A, Kahlen U, Moll M, Ringelstein M, Aktas O, Moldovan A, Waskönig J, Hartung H, Hefter H, Albrecht P. Long-term adherence and subjective treatment effect of botulinum toxin in different neurologic diseases Toxicon. 156. DOI: 10.1016/J.Toxicon.2018.11.161  0.257
2009 Hartung H. New cases of progressive multifocal leukoencephalopathy after treatment with natalizumab. Lancet Neurology. 8: 28-31. PMID 19081511 DOI: 10.1016/S1474-4422(08)70281-3  0.257
2006 Schroeter M, Zickler P, Denhardt DT, Hartung HP, Jander S. Increased thalamic neurodegeneration following ischaemic cortical stroke in osteopontin-deficient mice. Brain : a Journal of Neurology. 129: 1426-37. PMID 16636021 DOI: 10.1093/Brain/Awl094  0.257
1989 Hartung H, Toyka KV. Substance P, the Immune System and Inflammation International Reviews of Immunology. 4: 229-249. PMID 2484943 DOI: 10.3109/08830188909054420  0.256
2005 Stüve O, Cepok S, Elias B, Saleh A, Hartung HP, Hemmer B, Kieseier BC. Clinical stabilization and effective B-lymphocyte depletion in the cerebrospinal fluid and peripheral blood of a patient with fulminant relapsing-remitting multiple sclerosis. Archives of Neurology. 62: 1620-3. PMID 16216948 DOI: 10.1001/archneur.62.10.1620  0.256
2009 Otto F, Illes S, Opatz J, Laryea M, Theiss S, Hartung HP, Schnitzler A, Siebler M, Dihné M. Cerebrospinal fluid of brain trauma patients inhibits in vitro neuronal network function via NMDA receptors. Annals of Neurology. 66: 546-55. PMID 19847897 DOI: 10.1002/Ana.21808  0.255
2006 Kopadze T, Dehmel T, Hartung HP, Stüve O, Kieseier BC. Inhibition by mitoxantrone of in vitro migration of immunocompetent cells: a possible mechanism for therapeutic efficacy in the treatment of multiple sclerosis. Archives of Neurology. 63: 1572-8. PMID 17101825 DOI: 10.1001/archneur.63.11.1572  0.255
2012 Husseini L, Leussink VI, Warnke C, Hartung HP, Kieseier BC. Cannabinoids for symptomatic therapy of multiple sclerosis | Cannabinoidezur symptomatischen therapie der multiplen sklerose Nervenarzt. 83: 695-704. DOI: 10.1007/s00115-011-3401-9  0.255
2012 Jaerve A, Kruse F, Malik K, Hartung HP, Müller HW. Age-dependent modulation of cortical transcriptomes in spinal cord injury and repair. Plos One. 7: e49812. PMID 23236355 DOI: 10.1371/Journal.Pone.0049812  0.255
2019 Kraemer M, Schwitalla JC, Diesner F, Aktas O, Hartung HP, Berlit P. Clinical presentation of Moyamoya angiopathy in Europeans: experiences from Germany with 200 patients. Journal of Neurology. PMID 30868219 DOI: 10.1007/S00415-019-09277-1  0.255
2021 Wiendl H, Gold R, Berger T, Derfuss T, Linker R, Mäurer M, Stangel M, Aktas O, Baum K, Berghoff M, Bittner S, Chan A, Czaplinski A, Deisenhammer F, Di Pauli F, ... ... Hartung HP, et al. [Multiple sclerosis treatment consensus group (MSTCG): position paper on disease-modifying treatment of multiple sclerosis 2021 (white paper)]. Der Nervenarzt. PMID 34297142 DOI: 10.1007/s00115-021-01157-2  0.255
2012 Leussink VI, Husseini L, Warnke C, Broussalis E, Hartung HP, Kieseier BC. Symptomatic therapy in multiple sclerosis: the role of cannabinoids in treating spasticity. Therapeutic Advances in Neurological Disorders. 5: 255-66. PMID 22973422 DOI: 10.1177/1756285612453972  0.255
2012 Leussink VI, Husseini L, Warnke C, Broussalis E, Hartung HP, Kieseier BC. Symptomatic therapy in multiple sclerosis: the role of cannabinoids in treating spasticity. Therapeutic Advances in Neurological Disorders. 5: 255-66. PMID 22973422 DOI: 10.1177/1756285612453972  0.255
2005 Neuhaus O, Stüve O, Archelos JJ, Hartung HP. Putative mechanisms of action of statins in multiple sclerosis--comparison to interferon-beta and glatiramer acetate. Journal of the Neurological Sciences. 233: 173-7. PMID 15949504 DOI: 10.1016/j.jns.2005.03.030  0.254
2012 Menge T, Kieseier BC, Warnke C, Aktas O, Hartung HP. Alemtuzumab: A further option for treatment of multiple sclerosis | Alemtuzumab: Eine weitere chance zur therapie der multiplen sklerose Nervenarzt. 83: 487-501. PMID 22038387 DOI: 10.1007/s00115-011-3393-5  0.254
2012 Nolting T, Lindecke A, Hartung HP, Koutsilieri E, Maschke M, Husstedt IW, Sopper S, Stüve O, Arendt G. Cytokine levels in CSF and neuropsychological performance in HIV patients Journal of Neurovirology. 18: 157-161. PMID 22528475 DOI: 10.1007/S13365-012-0091-4  0.254
2021 Hartung HP, Meuth SG, Miller DM, Comi G. Stopping disease-modifying therapy in relapsing and progressive multiple sclerosis. Current Opinion in Neurology. PMID 33990101 DOI: 10.1097/WCO.0000000000000960  0.254
2020 Lee JI, Böcking T, Holle-Lee D, Malik RA, Kieseier BC, Hartung HP, Guthoff R, Kleinschnitz C, Stettner M. Corneal Confocal Microscopy Demonstrates Corneal Nerve Loss in Patients With Trigeminal Neuralgia. Frontiers in Neurology. 11: 661. PMID 32793098 DOI: 10.3389/Fneur.2020.00661  0.254
1995 Pette M, Gold R, Pette DF, Hartung H, Toyka KV. Mafosfamide induces DNA fragmentation and apoptosis in human T-lymphocytes A possible mechanism of its immunosuppressive action Immunopharmacology. 30: 59-69. PMID 7591714 DOI: 10.1016/0162-3109(95)00005-E  0.253
2020 Comi G, Bar-Or A, Lassmann H, Uccelli A, Hartung HP, Montalban X, Sørensen PS, Hohlfeld R, Hauser SL. The role of B cells in Multiple Sclerosis and related disorders. Annals of Neurology. PMID 33091175 DOI: 10.1002/ana.25927  0.253
2006 Hu W, Dehmel T, Pirhonen J, Hartung HP, Kieseier BC. Interleukin 23 in acute inflammatory demyelination of the peripheral nerve. Archives of Neurology. 63: 858-64. PMID 16769867 DOI: 10.1001/Archneur.63.6.858  0.253
2014 Hartung HP. Interferon β-1a for multiple sclerosis: old drug, new clothes. The Lancet. Neurology. 13: 638-9. PMID 24878062 DOI: 10.1016/S1474-4422(14)70100-0  0.253
1995 Gold R, Giegerich G, Hartung H, Toyka KV. T-cell receptor (TCR) usage in Lewis rat experimental autoimmune encephalomyelitis: TCR beta-chain-variable-region V beta 8.2-positive T cells are not essential for induction and course of disease Proceedings of the National Academy of Sciences of the United States of America. 92: 5850-5854. PMID 7597040 DOI: 10.1073/Pnas.92.13.5850  0.253
2018 Albrecht P, Jansen A, Lee JI, Moll M, Ringelstein M, Rosenthal D, Bigalke H, Aktas O, Hartung HP, Hefter H. High prevalence of neutralizing antibodies after long-term botulinum neurotoxin therapy. Neurology. PMID 30464031 DOI: 10.1212/Wnl.0000000000006688  0.253
2020 Cree BAC, Bowen JD, Hartung HP, Vermersch P, Hughes B, Damian D, Hyvert Y, Dangond F, Galazka A, Grosso M, Jones DL, Leist TP. Subgroup analysis of clinical and MRI outcomes in participants with a first clinical demyelinating event at risk of multiple sclerosis in the ORACLE-MS study. Multiple Sclerosis and Related Disorders. 49: 102695. PMID 33578191 DOI: 10.1016/j.msard.2020.102695  0.253
2008 Stüve O, Bennett JL, Hemmer B, Wiendl H, Racke MK, Bar-Or A, Hu W, Zivadinov R, Weber MS, Zamvil SS, Pacheco MF, Menge T, Hartung HP, Kieseier BC, Frohman EM. Pharmacological treatment of early multiple sclerosis. Drugs. 68: 73-83. PMID 18081373 DOI: 10.2165/00003495-200868010-00005  0.252
2014 Lill CM, Schilling M, Ansaloni S, Schröder J, Jaedicke M, Luessi F, Schjeide BM, Mashychev A, Graetz C, Akkad DA, Gerdes LA, Kroner A, Blaschke P, Hoffjan S, Winkelmann A, ... ... Hartung HP, et al. Assessment of microRNA-related SNP effects in the 3' untranslated region of the IL22RA2 risk locus in multiple sclerosis. Neurogenetics. 15: 129-34. PMID 24638856 DOI: 10.1007/S10048-014-0396-Y  0.252
2006 Neuhaus O, Wiendl H, Kieseier BC, Archelos JJ, Hemmer B, Stüve O, Hartung HP. Multiple sclerosis: Mitoxantrone promotes differential effects on immunocompetent cells in vitro. Journal of Neuroimmunology. 168: 128-37. PMID 16171875 DOI: 10.1016/j.jneuroim.2005.01.024  0.251
2008 Dihné M, Schuier FJ, Schuier M, Cordes J, Hartung HP, Knehans A, Mueller S. Hashimoto encephalopathy following iodine 131 (131I) radiotherapy of Graves disease [1] Archives of Neurology. 65: 282-293. PMID 18268203 DOI: 10.1001/Archneurol.2007.49  0.251
2023 Selmaj K, Cree BAC, Barnett M, Thompson A, Hartung HP. Multiple sclerosis: time for early treatment with high-efficacy drugs. Journal of Neurology. PMID 37851189 DOI: 10.1007/s00415-023-11969-8  0.251
2010 Chun J, Hartung HP. Mechanism of action of oral fingolimod (FTY720) in multiple sclerosis. Clinical Neuropharmacology. 33: 91-101. PMID 20061941 DOI: 10.1097/WNF.0b013e3181cbf825  0.251
2013 Hartung HP, Haas J, Meergans M, Tracik F, Ortler S. Interferon-β1b in multiple sclerosis therapy: More than 20 years clinical experience | Interferon-β1b in der Multiple-Sklerose-Therapie: Mehr als 20 Jahre klinische Erfahrung Nervenarzt. 84: 679-704. PMID 23669866 DOI: 10.1007/s00115-013-3781-0  0.251
2015 Hartung HP, Kappos L, Goodin DS, O'Connor P, Filippi M, Arnason B, Comi G, Cook S, Jeffery D, Petkau J, White R, Bogumil T, Beckmann K, Stemper B, Suarez G, et al. Predictors of disease activity in 857 patients with MS treated with interferon beta-1b. Journal of Neurology. PMID 26239222 DOI: 10.1007/S00415-015-7862-9  0.249
2019 van Schaik IN, Mielke O, Bril V, van Geloven N, Hartung HP, Lewis RA, Sobue G, Lawo JP, Praus M, Durn BL, Cornblath DR, Merkies ISJ. Long-term safety and efficacy of subcutaneous immunoglobulin IgPro20 in CIDP: PATH extension study. Neurology(R) Neuroimmunology & Neuroinflammation. 6: e590. PMID 31355323 DOI: 10.1212/Nxi.0000000000000590  0.249
1999 Hartung H. Infections and the Guillain-Barré syndrome. Journal of Neurology, Neurosurgery, and Psychiatry. 66: 277-277. PMID 10084522 DOI: 10.1136/Jnnp.66.3.277  0.249
2012 Gliem M, Hermsen D, Van Rooijen N, Hartung HP, Jander S. Secondary intracerebral hemorrhage due to early initiation of oral anticoagulation after ischemic stroke: An experimental study in mice Stroke. 43: 3352-3357. PMID 23117725 DOI: 10.1161/Strokeaha.112.666818  0.248
2022 Duarte-Silva E, Ulrich H, Oliveira-Giacomelli Á, Hartung HP, Meuth SG, Peixoto CA. The adenosinergic signaling in the pathogenesis and treatment of multiple sclerosis. Frontiers in Immunology. 13: 946698. PMID 35967385 DOI: 10.3389/fimmu.2022.946698  0.248
2020 Lee JI, Boerker L, Gemerzki L, Harmel J, Guthoff R, Aktas O, Gliem M, Jander S, Hartung HP, Albrecht P. Retinal Changes After Posterior Cerebral Artery Infarctions Display Different Patterns of the Nasal und Temporal Sector in a Case Series. Frontiers in Neurology. 11: 508. PMID 32582017 DOI: 10.3389/Fneur.2020.00508  0.248
1995 Archelos JJ, Toyka KV, Hartung HP. B cell responses to the PNS protein P0 in experimental autoimmune neuritis. Journal of the Neurological Sciences. 128: 111. PMID 7536814 DOI: 10.1016/0022-510X(94)00246-K  0.248
2019 Förster M, Küry P, Aktas O, Warnke C, Havla J, Hohlfeld R, Mares J, Hartung HP, Kremer D. Managing Risks with Immune Therapies in Multiple Sclerosis. Drug Safety. PMID 30607830 DOI: 10.1007/s40264-018-0782-8  0.247
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