Shad B. Smith - Publications

University of North Carolina, Chapel Hill, Chapel Hill, NC 
Pain genetics

55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Khoury S, Wang QP, Parisien M, Gris P, Bortsov AV, Linnstaedt SD, McLean SA, Tungate AS, Sofer T, Lee J, Louie T, Redline S, Kaunisto MA, Kalso EA, Munter HM, ... ... Smith SB, et al. Multi-ethnic GWAS and meta-analysis of sleep quality identify MPP6 as a novel gene that functions in sleep center neurons. Sleep. PMID 33034629 DOI: 10.1093/sleep/zsaa211  0.84
2020 van Tilburg MA, Parisien M, Boles RG, Drury GL, Smith-Voudouris J, Verma V, Khoury S, Chabot-Doré AJ, Nackley AG, Smith SB, Whitehead WE, Zolnoun DA, Slade GD, Tchivileva I, Maixner W, et al. A genetic polymorphism that is associated with mitochondrial energy metabolism increases risk of fibromyalgia. Pain. PMID 32658146 DOI: 10.1097/j.pain.0000000000001996  0.84
2019 Upadhyay U, Zhuang GZ, Diatchenko L, Parisien M, Kang Y, Sarantopoulos KD, Martin ER, Smith SB, Maixner W, Levitt RC. Profound analgesia is associated with a truncated peptide resulting from tissue specific alternative splicing of DRG CA8-204 regulated by an exon-level cis-eQTL. Plos Genetics. 15: e1008226. PMID 31199789 DOI: 10.1371/journal.pgen.1008226  0.84
2019 Khoury S, Piltonen MH, Ton AT, Cole T, Samoshkin A, Smith SB, Belfer I, Slade GD, Fillingim RB, Greenspan JD, Ohrbach R, Maixner W, Neely GG, Serohijos AWR, Diatchenko L. A functional substitution in the L-aromatic amino acid decarboxylase enzyme worsens somatic symptoms via a serotonergic pathway. Annals of Neurology. PMID 31177555 DOI: 10.1002/ana.25521  0.84
2019 Karasik D, Zillikens MC, Hsu YH, Aghdassi A, Akesson K, Amin N, Barroso I, Bennett DA, Bertram L, Bochud M, Borecki IB, Broer L, Buchman AS, Byberg L, Campbell H, ... ... Smith SB, et al. Disentangling the genetics of lean mass. The American Journal of Clinical Nutrition. PMID 30721968 DOI: 10.1093/ajcn/nqy272  0.84
2018 Smith SB, Parisien M, Bair E, Belfer I, Chabot-Doré AJ, Gris P, Khoury S, Tansley S, Torosyan Y, Zaykin DV, Bernhardt O, de Oliveira Serrano P, Gracely RH, Jain D, Järvelin MR, et al. Genome-wide association reveals contribution of MRAS to painful temporomandibular disorder in males. Pain. PMID 30431558 DOI: 10.1097/j.pain.0000000000001438  0.84
2018 Zhuang GZ, Upadhyay U, Tong X, Kang Y, Erasso DM, Fu ES, Sarantopoulos KD, Martin ER, Wiltshire T, Diatchenko L, Smith SB, Maixner W, Levitt RC. Human carbonic anhydrase-8 AAV8 gene therapy inhibits nerve growth factor signaling producing prolonged analgesia and anti-hyperalgesia in mice. Gene Therapy. PMID 29789638 DOI: 10.1038/s41434-018-0018-7  0.84
2018 Sigurdsson MI, Waldron NH, Bortsov AV, Smith SB, Maixner W. Genomics of Cardiovascular Measures of Autonomic Tone. Journal of Cardiovascular Pharmacology. PMID 29300220 DOI: 10.1097/FJC.0000000000000559  0.84
2017 Fu ES, Erasso DM, Zhuang GZ, Upadhyay U, Ozdemir M, Wiltshire T, Sarantopoulos KD, Smith SB, Maixner W, Martin ER, Levitt RC. Impact of human CA8 on thermal antinociception in relation to morphine equivalence in mice. Neuroreport. PMID 28902707 DOI: 10.1097/WNR.0000000000000872  0.84
2017 Levitt AE, Galor A, Chowdhury AR, Felix ER, Sarantopoulos CD, Zhuang GY, Patin D, Maixner W, Smith SB, Martin ER, Levitt RC. [EXPRESS] Evidence that Dry Eye Represents a Chronic Overlapping Pain Condition. Molecular Pain. 13: 1744806917729306. PMID 28814146 DOI: 10.1177/1744806917729306  0.84
2017 Martin LJ, Smith SB, Khoutorsky A, Magnussen CA, Samoshkin A, Sorge RE, Cho C, Yosefpour N, Sivaselvachandran S, Tohyama S, Cole T, Khuong TM, Mir E, Gibson DG, Wieskopf JS, et al. Epiregulin and EGFR interactions are involved in pain processing. The Journal of Clinical Investigation. PMID 28783046 DOI: 10.1172/JCI87406  0.84
2017 Parisien M, Khoury S, Chabot-Doré AJ, Sotocinal SG, Slade GD, Smith SB, Fillingim RB, Ohrbach R, Greenspan JD, Maixner W, Mogil JS, Belfer I, Diatchenko L. Effect of Human Genetic Variability on Gene Expression in Dorsal Root Ganglia and Association with Pain Phenotypes. Cell Reports. 19: 1940-1952. PMID 28564610 DOI: 10.1016/j.celrep.2017.05.018  0.84
2017 Levitt RC, Zhuang GY, Kang Y, Erasso DM, Upadhyay U, Ozdemir M, Fu ES, Sarantopoulos KD, Smith SB, Maixner W, Diatchenko L, Martin ER, Wiltshire T. Car8 dorsal root ganglion expression and genetic regulation of analgesic responses are associated with a cis-eQTL in mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. PMID 28547032 DOI: 10.1007/s00335-017-9694-7  0.84
2016 Maixner W, Fillingim RB, Williams DA, Smith SB, Slade GD. Overlapping Chronic Pain Conditions: Implications for Diagnosis and Classification. The Journal of Pain : Official Journal of the American Pain Society. 17: T93-T107. PMID 27586833 DOI: 10.1016/j.jpain.2016.06.002  0.84
2016 Bair E, Gaynor S, Slade GD, Ohrbach R, Fillingim RB, Greenspan JD, Dubner R, Smith SB, Diatchenko L, Maixner W. Identification of Clusters of Individuals Relevant to Temporomandibular Disorders and Other Chronic Pain Conditions: The OPPERA Study. Pain. PMID 26928952 DOI: 10.1097/j.pain.0000000000000518  0.84
2015 Meloto CB, Bortsov A, Bair E, Helgeson E, Ostrom C, Smith S, Dubner R, Slade GD, Fillingim RB, Greenspan JD, Ohrbach R, Maixner W, McLean S, Diatchenko L. Modification of COMT-dependent pain sensitivity by psychological stress and sex. Pain. PMID 26675825 DOI: 10.1097/j.pain.0000000000000449  0.84
2015 Hsu YH, Liu Y, Hannan MT, Maixner W, Smith SB, Diatchenko L, Golightly YM, Menz HB, Kraus VB, Doherty M, Wilson AG, Jordan JM. Genome-wide association meta-analyses to identify common genetic variants associated with hallux valgus in Caucasian and African Americans. Journal of Medical Genetics. PMID 26337638 DOI: 10.1136/jmedgenet-2015-103142  0.84
2015 Meloto CB, Segall SK, Smith S, Parisien M, Shabalina SA, Rizzatti-Barbosa CM, Gauthier J, Tsao D, Convertino M, Piltonen MH, Slade GD, Fillingim RB, Greenspan JD, Ohrbach R, Knott C, et al. COMT gene locus: new functional variants. Pain. 156: 2072-83. PMID 26207649 DOI: 10.1097/j.pain.0000000000000273  0.84
2015 Slade GD, Sanders AE, Ohrbach R, Bair E, Maixner W, Greenspan JD, Fillingim RB, Smith S, Diatchenko L. COMT Diplotype Amplifies Effect of Stress on Risk of Temporomandibular Pain. Journal of Dental Research. 94: 1187-95. PMID 26198390 DOI: 10.1177/0022034515595043  0.84
2015 Ciszek BP, Khan AA, Dang H, Slade GD, Smith S, Bair E, Maixner W, Zolnoun D, Nackley AG. MicroRNA expression profiles differentiate chronic pain condition subtypes. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 26166255 DOI: 10.1016/j.trsl.2015.06.008  0.84
2015 Wieskopf JS, Mathur J, Limapichat W, Post MR, Al-Qazzaz M, Sorge RE, Martin LJ, Zaykin DV, Smith SB, Freitas K, Austin JS, Dai F, Zhang J, Marcovitz J, Tuttle AH, et al. The nicotinic α6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2/3 receptors. Science Translational Medicine. 7: 287ra72. PMID 25972004 DOI: 10.1126/scitranslmed.3009986  0.84
2015 Zhuang GZ, Keeler B, Grant J, Bianchi L, Fu ES, Zhang YP, Erasso DM, Cui JG, Wiltshire T, Li Q, Hao S, Sarantopoulos KD, Candiotti K, Wishnek SM, Smith SB, et al. Carbonic anhydrase-8 regulates inflammatory pain by inhibiting the ITPR1-cytosolic free calcium pathway. Plos One. 10: e0118273. PMID 25734498 DOI: 10.1371/journal.pone.0118273  0.84
2015 Hsu YH, Liu Y, Hannan MT, Maixner W, Smith SB, Diatchenko L, Golightly YM, Menz HB, Kraus VB, Doherty M, Wilson AG, Jordan JM. Genome-wide association meta-analyses to identify common genetic variants associated with hallux valgus in Caucasian and African Americans Journal of Medical Genetics. DOI: 10.1136/jmedgenet-2015-103142  0.84
2014 Smith SB, Reenilä I, Männistö PT, Slade GD, Maixner W, Diatchenko L, Nackley AG. Epistasis between polymorphisms in COMT, ESR1, and GCH1 influences COMT enzyme activity and pain. Pain. 155: 2390-9. PMID 25218601 DOI: 10.1016/j.pain.2014.09.009  0.84
2013 Smith SB, Mir E, Bair E, Slade GD, Dubner R, Fillingim RB, Greenspan JD, Ohrbach R, Knott C, Weir B, Maixner W, Diatchenko L. Genetic variants associated with development of TMD and its intermediate phenotypes: the genetic architecture of TMD in the OPPERA prospective cohort study. The Journal of Pain : Official Journal of the American Pain Society. 14: T91-101.e1-3. PMID 24275226 DOI: 10.1016/j.jpain.2013.09.004  0.84
2013 Ohrbach R, Bair E, Fillingim RB, Gonzalez Y, Gordon SM, Lim PF, Ribeiro-Dasilva M, Diatchenko L, Dubner R, Greenspan JD, Knott C, Maixner W, Smith SB, Slade GD. Clinical orofacial characteristics associated with risk of first-onset TMD: the OPPERA prospective cohort study. The Journal of Pain : Official Journal of the American Pain Society. 14: T33-50. PMID 24275222 DOI: 10.1016/j.jpain.2013.07.018  0.84
2013 Bair E, Brownstein NC, Ohrbach R, Greenspan JD, Dubner R, Fillingim RB, Maixner W, Smith SB, Diatchenko L, Gonzalez Y, Gordon SM, Lim PF, Ribeiro-Dasilva M, Dampier D, Knott C, et al. Study protocol, sample characteristics, and loss to follow-up: the OPPERA prospective cohort study. The Journal of Pain : Official Journal of the American Pain Society. 14: T2-19. PMID 24275220 DOI: 10.1016/j.jpain.2013.06.006  0.84
2013 Slade GD, Fillingim RB, Sanders AE, Bair E, Greenspan JD, Ohrbach R, Dubner R, Diatchenko L, Smith SB, Knott C, Maixner W. Summary of findings from the OPPERA prospective cohort study of incidence of first-onset temporomandibular disorder: implications and future directions. The Journal of Pain : Official Journal of the American Pain Society. 14: T116-24. PMID 24275219 DOI: 10.1016/j.jpain.2013.09.010  0.84
2013 Slade GD, Smith SB, Zaykin DV, Tchivileva IE, Gibson DG, Yuryev A, Mazo I, Bair E, Fillingim R, Ohrbach R, Greenspan J, Maixner W, Diatchenko L. Facial pain with localized and widespread manifestations: separate pathways of vulnerability. Pain. 154: 2335-43. PMID 23867732 DOI: 10.1016/j.pain.2013.07.009  0.84
2013 Belfer I, Segall SK, Lariviere WR, Smith SB, Dai F, Slade GD, Rashid NU, Mogil JS, Campbell CM, Edwards RR, Liu Q, Bair E, Maixner W, Diatchenko L. Pain modality- and sex-specific effects of COMT genetic functional variants. Pain. 154: 1368-76. PMID 23701723 DOI: 10.1016/j.pain.2013.04.028  0.84
2013 Monda KL, Chen GK, Taylor KC, Palmer C, Edwards TL, Lange LA, Ng MC, Adeyemo AA, Allison MA, Bielak LF, Chen G, Graff M, Irvin MR, Rhie SK, Li G, ... ... Smith SB, et al. A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nature Genetics. 45: 690-6. PMID 23583978 DOI: 10.1038/ng.2608  1
2013 Diatchenko L, Fillingim RB, Smith SB, Maixner W. The phenotypic and genetic signatures of common musculoskeletal pain conditions. Nature Reviews. Rheumatology. 9: 340-50. PMID 23545734 DOI: 10.1038/nrrheum.2013.43  0.84
2013 Slade GD, Sanders AE, Bair E, Brownstein N, Dampier D, Knott C, Fillingim R, Maixner WO, Smith S, Greenspan J, Dubner R, Ohrbach R. Preclinical episodes of orofacial pain symptoms and their association with health care behaviors in the OPPERA prospective cohort study. Pain. 154: 750-60. PMID 23531476 DOI: 10.1016/j.pain.2013.01.014  0.84
2012 Neely GG, Rao S, Costigan M, Mair N, Racz I, Milinkeviciute G, Meixner A, Nayanala S, Griffin RS, Belfer I, Dai F, Smith S, Diatchenko L, Marengo S, Haubner BJ, et al. Construction of a global pain systems network highlights phospholipid signaling as a regulator of heat nociception. Plos Genetics. 8: e1003071. PMID 23236288 DOI: 10.1371/journal.pgen.1003071  0.84
2012 Sorge RE, Trang T, Dorfman R, Smith SB, Beggs S, Ritchie J, Austin JS, Zaykin DV, Vander Meulen H, Costigan M, Herbert TA, Yarkoni-Abitbul M, Tichauer D, Livneh J, Gershon E, et al. Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity. Nature Medicine. 18: 595-9. PMID 22447075 DOI: 10.1038/nm.2710  0.84
2012 Smith SB, Maixner DW, Fillingim RB, Slade G, Gracely RH, Ambrose K, Zaykin DV, Hyde C, John S, Tan K, Maixner W, Diatchenko L. Large candidate gene association study reveals genetic risk factors and therapeutic targets for fibromyalgia. Arthritis and Rheumatism. 64: 584-93. PMID 21905019 DOI: 10.1002/art.33338  0.84
2011 Smith SB, Maixner DW, Greenspan JD, Dubner R, Fillingim RB, Ohrbach R, Knott C, Slade GD, Bair E, Gibson DG, Zaykin DV, Weir BS, Maixner W, Diatchenko L. Potential genetic risk factors for chronic TMD: genetic associations from the OPPERA case control study. The Journal of Pain : Official Journal of the American Pain Society. 12: T92-101. PMID 22074755 DOI: 10.1016/j.jpain.2011.08.005  0.84
2011 Mogil JS, Sorge RE, LaCroix-Fralish ML, Smith SB, Fortin A, Sotocinal SG, Ritchie J, Austin JS, Schorscher-Petcu A, Melmed K, Czerminski J, Bittong RA, Mokris JB, Neubert JK, Campbell CM, et al. Pain sensitivity and vasopressin analgesia are mediated by a gene-sex-environment interaction. Nature Neuroscience. 14: 1569-73. PMID 22019732 DOI: 10.1038/nn.2941  0.84
2011 Slade GD, Conrad MS, Diatchenko L, Rashid NU, Zhong S, Smith S, Rhodes J, Medvedev A, Makarov S, Maixner W, Nackley AG. Cytokine biomarkers and chronic pain: association of genes, transcription, and circulating proteins with temporomandibular disorders and widespread palpation tenderness. Pain. 152: 2802-12. PMID 22000099 DOI: 10.1016/j.pain.2011.09.005  0.84
2010 Neely GG, Hess A, Costigan M, Keene AC, Goulas S, Langeslag M, Griffin RS, Belfer I, Dai F, Smith SB, Diatchenko L, Gupta V, Xia CP, Amann S, Kreitz S, et al. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Cell. 143: 628-38. PMID 21074052 DOI: 10.1016/j.cell.2010.09.047  0.84
2010 Costigan M, Belfer I, Griffin RS, Dai F, Barrett LB, Coppola G, Wu T, Kiselycznyk C, Poddar M, Lu Y, Diatchenko L, Smith S, Cobos EJ, Zaykin D, Allchorne A, et al. Multiple chronic pain states are associated with a common amino acid-changing allele in KCNS1. Brain : a Journal of Neurology. 133: 2519-27. PMID 20724292 DOI: 10.1093/brain/awq195  0.84
2010 Tchivileva IE, Lim PF, Smith SB, Slade GD, Diatchenko L, McLean SA, Maixner W. Effect of catechol-O-methyltransferase polymorphism on response to propranolol therapy in chronic musculoskeletal pain: a randomized, double-blind, placebo-controlled, crossover pilot study. Pharmacogenetics and Genomics. 20: 239-48. PMID 20216107 DOI: 10.1097/FPC.0b013e328337f9ab  0.84
2010 Reimann F, Cox JJ, Belfer I, Diatchenko L, Zaykin DV, McHale DP, Drenth JP, Dai F, Wheeler J, Sanders F, Wood L, Wu TX, Karppinen J, Nikolajsen L, Männikkö M, ... ... Smith S, et al. Pain perception is altered by a nucleotide polymorphism in SCN9A. Proceedings of the National Academy of Sciences of the United States of America. 107: 5148-53. PMID 20212137 DOI: 10.1073/pnas.0913181107  0.84
2010 Lim PF, Smith S, Bhalang K, Slade GD, Maixner W. Development of temporomandibular disorders is associated with greater bodily pain experience. The Clinical Journal of Pain. 26: 116-20. PMID 20090437 DOI: 10.1097/AJP.0b013e3181c507ef  0.84
2009 LaCroix-Fralish ML, Mo G, Smith SB, Sotocinal SG, Ritchie J, Austin JS, Melmed K, Schorscher-Petcu A, Laferriere AC, Lee TH, Romanovsky D, Liao G, Behlke MA, Clark DJ, Peltz G, et al. The beta3 subunit of the Na+,K+-ATPase mediates variable nociceptive sensitivity in the formalin test. Pain. 144: 294-302. PMID 19464798 DOI: 10.1016/j.pain.2009.04.028  0.84
2009 Kest B, Smith SB, Schorscher-Petcu A, Austin JS, Ritchie J, Klein G, Rossi GC, Fortin A, Mogil JS. Gnao1 (G alphaO protein) is a likely genetic contributor to variation in physical dependence on opioids in mice. Neuroscience. 162: 1255-64. PMID 19460419 DOI: 10.1016/j.neuroscience.2009.05.027  0.84
2008 Smith SB, Marker CL, Perry C, Liao G, Sotocinal SG, Austin JS, Melmed K, Clark JD, Peltz G, Wickman K, Mogil JS. Quantitative trait locus and computational mapping identifies Kcnj9 (GIRK3) as a candidate gene affecting analgesia from multiple drug classes. Pharmacogenetics and Genomics. 18: 231-41. PMID 18300945 DOI: 10.1097/FPC.0b013e3282f55ab2  0.84
2006 Mogil JS, Ritchie J, Sotocinal SG, Smith SB, Croteau S, Levitin DJ, Naumova AK. Screening for pain phenotypes: analysis of three congenic mouse strains on a battery of nine nociceptive assays. Pain. 126: 24-34. PMID 16842916 DOI: 10.1016/j.pain.2006.06.004  0.84
2006 Langford DJ, Crager SE, Shehzad Z, Smith SB, Sotocinal SG, Levenstadt JS, Chanda ML, Levitin DJ, Mogil JS. Social modulation of pain as evidence for empathy in mice. Science (New York, N.Y.). 312: 1967-70. PMID 16809545 DOI: 10.1126/science.1128322  0.84
2006 Green AD, Young KK, Lehto SG, Smith SB, Mogil JS. Influence of genotype, dose and sex on pruritogen-induced scratching behavior in the mouse. Pain. 124: 50-8. PMID 16697529 DOI: 10.1016/j.pain.2006.03.023  0.84
2005 Mogil JS, Smith SB, O'Reilly MK, Plourde G. Influence of nociception and stress-induced antinociception on genetic variation in isoflurane anesthetic potency among mouse strains. Anesthesiology. 103: 751-8. PMID 16192767 DOI: 10.1097/00000542-200510000-00013  0.84
2005 Mogil JS, Miermeister F, Seifert F, Strasburg K, Zimmermann K, Reinold H, Austin JS, Bernardini N, Chesler EJ, Hofmann HA, Hordo C, Messlinger K, Nemmani KV, Rankin AL, Ritchie J, ... ... Smith SB, et al. Variable sensitivity to noxious heat is mediated by differential expression of the CGRP gene. Proceedings of the National Academy of Sciences of the United States of America. 102: 12938-43. PMID 16118273 DOI: 10.1073/pnas.0503264102  0.84
2005 Mogil JS, Ritchie J, Smith SB, Strasburg K, Kaplan L, Wallace MR, Romberg RR, Bijl H, Sarton EY, Fillingim RB, Dahan A. Melanocortin-1 receptor gene variants affect pain and mu-opioid analgesia in mice and humans. Journal of Medical Genetics. 42: 583-7. PMID 15994880 DOI: 10.1136/jmg.2004.027698  0.84
2004 Smith SB, Crager SE, Mogil JS. Paclitaxel-induced neuropathic hypersensitivity in mice: responses in 10 inbred mouse strains. Life Sciences. 74: 2593-604. PMID 15041441 DOI: 10.1016/j.lfs.2004.01.002  0.84
2003 Wilson SG, Smith SB, Chesler EJ, Melton KA, Haas JJ, Mitton B, Strasburg K, Hubert L, Rodriguez-Zas SL, Mogil JS. The heritability of antinociception: common pharmacogenetic mediation of five neurochemically distinct analgesics. The Journal of Pharmacology and Experimental Therapeutics. 304: 547-59. PMID 12538806 DOI: 10.1124/jpet.102.041889  0.84
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