Phillip Needleman - Related publications

Washington University School of Medicine, St. Louis, MO, United States 
prostaglandins, cyclooxygenase, COX inhibitors
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21 most relevant papers in past 60 days:
Year Citation  Score
2022 Yadav S, Srivastava S, Singh G. Platelet-rich plasma exhibits anti-inflammatory effect and attenuates cardiomyocyte damage by reducing NF-κB and enhancing VEGF expression in isoproterenol induced cardiotoxicity model. Environmental Toxicology. PMID 35014750 DOI: 10.1002/tox.23456   
2022 Falcón D, Mayoral I, Ordóñez A, Smani T. Implication of CREB in the calcium regulation by ischemia/reperfusion in cardiomyocytes. The Journal of General Physiology. 154. PMID 34766979 DOI: 10.1085/jgp.2021ecc7   
2022 Liao M, Zhao Y, Xie Q, Yang C, Lin C, Wang G, Liu B, Zhu L. Main active components of Si-Miao-Yong-An decoction (SMYAD) attenuate autophagy and apoptosis via the PDE5A-AKT and TLR4-NOX4 pathways in isoproterenol (ISO)-induced heart failure models. Pharmacological Research. 106077. PMID 35026404 DOI: 10.1016/j.phrs.2022.106077   
2022 Kita T, Kitamura K. Translational studies of adrenomedullin and related peptides regarding cardiovascular diseases. Hypertension Research : Official Journal of the Japanese Society of Hypertension. PMID 34992239 DOI: 10.1038/s41440-021-00806-y   
2022 Chen FX, Wan Q, Li QL, Fang J, Peng L, Hu J. Substance P prevents doxorubicin‑induced cardiomyocyte injury by regulating apoptosis and autophagy: and evidence. Molecular Medicine Reports. 25. PMID 34913064 DOI: 10.3892/mmr.2021.12566   
2022 Shi W, Ye H, Deng Y, Chen S, Xiao W, Wang Z, Xiong Z, Zhao L. Yaobitong capsules reshape and rebalance the gut microbiota and metabolites of arthritic rats: An integrated study of microbiome and fecal metabolomics analysis. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1190: 123096. PMID 34998201 DOI: 10.1016/j.jchromb.2021.123096   
2022 Minato T, Nakamura N, Saiki T, Miyabe M, Ito M, Matsubara T, Naruse K. β-Aminoisobutyric acid, L-BAIBA, protects PC12 cells from hydrogen peroxide-induced oxidative stress and apoptosis via activation of the AMPK and PI3K/Akt pathway. Ibro Neuroscience Reports. 12: 65-72. PMID 35024688 DOI: 10.1016/j.ibneur.2021.12.001   
2022 Williams D, Mahmoud M, Liu R, Andueza A, Kumar S, Kang DW, Zhang J, Tamargo I, Villa-Roel N, Baek KI, Lee H, An Y, Zhang L, Tate EW, Bagchi P, et al. Stable flow-induced expression of KLK10 inhibits endothelial inflammation and atherosclerosis. Elife. 11. PMID 35014606 DOI: 10.7554/eLife.72579   
2022 Tang H, Zhao J, Feng R, Pu P, Wen L. Reducing oxidative stress may be important for treating pirarubicin-induced cardiotoxicity with schisandrin B. Experimental and Therapeutic Medicine. 23: 68. PMID 34934439 DOI: 10.3892/etm.2021.10991   
2022 Lee D, Lee E, Jang S, Kim K, Cho E, Mun SJ, Son W, Jeon HI, Kim HK, Jeong YJ, Lee Y, Oh JE, Yoo HH, Lee Y, Min SJ, et al. Discovery of Rv3364c-Derived Small Molecules as Potential Therapeutic Agents to Target SNX9 for Sepsis. Journal of Medicinal Chemistry. PMID 34982557 DOI: 10.1021/acs.jmedchem.1c01551   
2022 Im NR, Kim B, Jung KY, Baek SK. Matrix metalloproteinase-7 induces E-cadherin cleavage in acid-exposed primary human pharyngeal epithelial cells via the ROS/ERK/c-Jun pathway. Journal of Molecular Medicine (Berlin, Germany). PMID 34973082 DOI: 10.1007/s00109-021-02166-z   
2022 Huang W, Liu N, Tong X, Du Y. Sildenafil protects against pulmonary hypertension induced by hypoxia in neonatal rats via activation of PPARγ‑mediated downregulation of TRPC. International Journal of Molecular Medicine. 49. PMID 34935055 DOI: 10.3892/ijmm.2021.5074   
2022 Chi PL, Cheng CC, Hung CC, Wang MT, Liu HY, Ke MW, Shen MC, Lin KC, Kuo SH, Hsieh PP, Wann SR, Huang WC. MMP-10 from M1 macrophages promotes pulmonary vascular remodeling and pulmonary arterial hypertension. International Journal of Biological Sciences. 18: 331-348. PMID 34975336 DOI: 10.7150/ijbs.66472   
2022 Martín-Cámara O, Arribas M, Wells G, Morales-Tenorio M, Martín-Requero Á, Porras G, Martínez A, Giorgi G, López-Alvarado P, Lastres-Becker I, Menéndez JC. Multitarget Hybrid Fasudil Derivatives as a New Approach to the Potential Treatment of Amyotrophic Lateral Sclerosis. Journal of Medicinal Chemistry. PMID 34985276 DOI: 10.1021/acs.jmedchem.1c01255   
2022 Xiao H, Wu D, Yang T, Fu W, Yang L, Hu C, Wan H, Hu X, Zhang C, Wu T. Extracellular vesicles derived from HBMSCs improved myocardial infarction through inhibiting zinc finger antisense 1 and activating Akt/Nrf2/HO-1 pathway. Bioengineered. 13: 905-916. PMID 34974805 DOI: 10.1080/21655979.2021.2014389   
2022 Jing H, Wang F, Gao XJ. Lithium intoxication induced pyroptosis via ROS/NF-κB/NLRP3 inflammasome regulatory networks in kidney of mice. Environmental Toxicology. PMID 34984798 DOI: 10.1002/tox.23446   
2022 Gong J, Luo M, Yong Y, Zhong S, Li P. Alamandine alleviates hypertension and renal damage via oxidative-stress attenuation in Dahl rats. Cell Death Discovery. 8: 22. PMID 35022384 DOI: 10.1038/s41420-022-00822-y   
2022 Heo JH, Lee SR, Jo SL, Yang H, Lee HW, Hong EJ. Letrozole Accelerates Metabolic Remodeling through Activation of Glycolysis in Cardiomyocytes: A Role beyond Hormone Regulation. International Journal of Molecular Sciences. 23. PMID 35008972 DOI: 10.3390/ijms23010547   
2022 Liu Y, Wu Z, Guo K, Zhou Y, Xing K, Zheng J, Sun Y, Zhang J. Metallothionein-1 gene from Exopalaemon carinicauda and its response to heavy metal ions challenge. Marine Pollution Bulletin. 175: 113324. PMID 35051848 DOI: 10.1016/j.marpolbul.2022.113324   
2022 Yang XX, Zhao ZY. miR-30a-5p inhibits the proliferation and collagen formation of cardiac fibroblasts in diabetic cardiomyopathy. Canadian Journal of Physiology and Pharmacology. 1-9. PMID 35025607 DOI: 10.1139/cjpp-2021-0280   
2022 Deng J, Wang SH, Zheng XM, Tang ZM. Calcitonin Gene-Related Peptide Attenuates Hyperoxia-Induced Oxidative Damage in Alveolar Epithelial Type II Cells Through Regulating Viability and Transdifferentiation. Inflammation. PMID 34988756 DOI: 10.1007/s10753-021-01591-z