| Year |
Citation |
Score |
| 2018 |
Perez-Borrajero C, Lin CS, Okon M, Scheu K, Graves BJ, Murphy MEP, McIntosh LP. The Biophysical Basis for Phosphorylation-Enhanced DNA-Binding Autoinhibition of the ETS1 Transcription Factor. Journal of Molecular Biology. PMID 30597162 DOI: 10.2210/Pdb6Dat/Pdb |
0.452 |
|
| 2018 |
Madison BJ, Clark KA, Bhachech N, Hollenhorst P, Graves BJ, Currie SL. Electrostatic repulsion causes anticooperative DNA binding between tumor suppressor ETS transcription factors and JUN-FOS at composite DNA sites. The Journal of Biological Chemistry. PMID 30315111 DOI: 10.1074/Jbc.Ra118.003352 |
0.767 |
|
| 2018 |
Currie SL, Warner SL, Vankayalapati H, Liu X, Sharma S, Bearss DJ, Graves BJ. Development of High-Throughput Screening Assays for Inhibitors of ETS Transcription Factors. Slas Discovery : Advancing Life Sciences R & D. 2472555218798571. PMID 30204534 DOI: 10.1177/2472555218798571 |
0.331 |
|
| 2017 |
Currie SL, Doane JJ, Evans KS, Bhachech N, Madison BJ, Lau DKW, McIntosh LP, Skalicky JJ, Clark KA, Graves BJ. ETV4 and AP1 transcription factors form multivalent interactions with three sites on the MED25 activator-interacting domain. Journal of Molecular Biology. PMID 28728983 DOI: 10.1016/J.Jmb.2017.06.024 |
0.424 |
|
| 2017 |
Currie SL, Lau DK, Doane JJ, Whitby FG, Okon M, McIntosh LP, Graves BJ. Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETS factors ETV1, ETV4 and ETV5. Nucleic Acids Research. PMID 28161714 DOI: 10.1093/Nar/Gkx068 |
0.474 |
|
| 2016 |
Kikani CK, Wu X, Paul L, Sabic H, Shen Z, Shakya A, Keefe A, Villanueva C, Kardon G, Graves B, Tantin D, Rutter J. Pask integrates hormonal signaling with histone modification via Wdr5 phosphorylation to drive myogenesis. Elife. 5. PMID 27661449 DOI: 10.7554/Elife.17985 |
0.636 |
|
| 2016 |
Desjardins G, Okon M, Graves BJ, McIntosh LP. Conformational dynamics and the binding of specific and non-specific DNA by the autoinhibited transcription factor Ets-1. Biochemistry. PMID 27362745 DOI: 10.1021/Acs.Biochem.6B00460 |
0.424 |
|
| 2016 |
De S, Okon M, Graves BJ, McIntosh LP. Autoinhibition of ETV6 DNA-binding is established by the stability of its inhibitory helix. Journal of Molecular Biology. PMID 26920109 DOI: 10.1016/J.Jmb.2016.02.020 |
0.413 |
|
| 2016 |
Kikani CK, Wu X, Paul L, Sabic H, Shen Z, Shakya A, Keefe A, Villanueva C, Kardon G, Graves B, Tantin D, Rutter J. Author response: Pask integrates hormonal signaling with histone modification via Wdr5 phosphorylation to drive myogenesis Elife. DOI: 10.7554/Elife.17985.041 |
0.554 |
|
| 2014 |
Desjardins G, Meeker CA, Bhachech N, Currie SL, Okon M, Graves BJ, McIntosh LP. Synergy of aromatic residues and phosphoserines within the intrinsically disordered DNA-binding inhibitory elements of the Ets-1 transcription factor. Proceedings of the National Academy of Sciences of the United States of America. 111: 11019-24. PMID 25024220 DOI: 10.1073/Pnas.1401891111 |
0.803 |
|
| 2014 |
De S, Chan AC, Coyne HJ, Bhachech N, Hermsdorf U, Okon M, Murphy ME, Graves BJ, McIntosh LP. Steric mechanism of auto-inhibitory regulation of specific and non-specific DNA binding by the ETS transcriptional repressor ETV6. Journal of Molecular Biology. 426: 1390-406. PMID 24333486 DOI: 10.1016/J.Jmb.2013.11.031 |
0.448 |
|
| 2013 |
De S, McIntosh L, Chan A, Coyne H, Okon M, Graves B, Murphy M. Structure of uninhibited ETV6 ETS domain Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Md5/Pdb |
0.392 |
|
| 2012 |
Ramirez K, Chandler KJ, Spaulding C, Zandi S, Sigvardsson M, Graves BJ, Kee BL. Gene deregulation and chronic activation in natural killer cells deficient in the transcription factor ETS1. Immunity. 36: 921-32. PMID 22608498 DOI: 10.1016/J.Immuni.2012.04.006 |
0.674 |
|
| 2012 |
Coyne HJ, De S, Okon M, Green SM, Bhachech N, Graves BJ, McIntosh LP. Autoinhibition of ETV6 (TEL) DNA binding: appended helices sterically block the ETS domain. Journal of Molecular Biology. 421: 67-84. PMID 22584210 DOI: 10.1016/J.Jmb.2012.05.010 |
0.464 |
|
| 2012 |
Hollenhorst PC, Ferris MW, Hull MA, Chae H, Kim S, Graves BJ. Abstract PR1: Oncogenic ETS over-expression mimics RAS/MAPK signaling in prostate cells Cancer Research. 72: PR1-PR1. DOI: 10.1158/1538-7445.PRCA2012-PR1 |
0.662 |
|
| 2011 |
Hollenhorst PC, Ferris MW, Hull MA, Chae H, Kim S, Graves BJ. Oncogenic ETS proteins mimic activated RAS/MAPK signaling in prostate cells. Genes & Development. 25: 2147-57. PMID 22012618 DOI: 10.1101/Gad.17546311 |
0.734 |
|
| 2011 |
Hollenhorst PC, McIntosh LP, Graves BJ. Genomic and biochemical insights into the specificity of ETS transcription factors. Annual Review of Biochemistry. 80: 437-71. PMID 21548782 DOI: 10.1146/Annurev.Biochem.79.081507.103945 |
0.777 |
|
| 2011 |
Hollenhorst PC, Paul L, Ferris MW, Graves BJ. The ETS gene ETV4 is required for anchorage-independent growth and a cell proliferation gene expression program in PC3 prostate cells. Genes & Cancer. 1: 1044-1052. PMID 21373373 DOI: 10.1177/1947601910395578 |
0.684 |
|
| 2011 |
Lee G, Donaldson L, Pufall M, Kang H, Gentile L, Pot I, Graves B, McIntosh L. Backbone and Sidechain 1H, 13C, and 15N Chemical Shift Assignments and Backbone 15N Relaxation Parameters for Murine Ets-1 deltaN301 Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr5991 |
0.646 |
|
| 2010 |
Thyagarajan B, Blaszczak AG, Chandler KJ, Watts JL, Johnson WE, Graves BJ. ETS-4 is a transcriptional regulator of life span in Caenorhabditis elegans. Plos Genetics. 6: e1001125. PMID 20862312 DOI: 10.1371/Journal.Pgen.1001125 |
0.708 |
|
| 2010 |
Nelson ML, Kang HS, Lee GM, Blaszczak AG, Lau DK, McIntosh LP, Graves BJ. Ras signaling requires dynamic properties of Ets1 for phosphorylation-enhanced binding to coactivator CBP. Proceedings of the National Academy of Sciences of the United States of America. 107: 10026-31. PMID 20534573 DOI: 10.1073/Pnas.0915137107 |
0.337 |
|
| 2010 |
Oler AJ, Alla RK, Roberts DN, Wong A, Hollenhorst PC, Chandler KJ, Cassiday PA, Nelson CA, Hagedorn CH, Graves BJ, Cairns BR. Human RNA polymerase III transcriptomes and relationships to Pol II promoter chromatin and enhancer-binding factors. Nature Structural & Molecular Biology. 17: 620-8. PMID 20418882 DOI: 10.1038/Nsmb.1801 |
0.75 |
|
| 2010 |
Green SM, Coyne HJ, McIntosh LP, Graves BJ. DNA binding by the ETS protein TEL (ETV6) is regulated by autoinhibition and self-association. The Journal of Biological Chemistry. 285: 18496-504. PMID 20400516 DOI: 10.1074/Jbc.M109.096958 |
0.417 |
|
| 2010 |
Clement NL, Snell Q, Clement MJ, Hollenhorst PC, Purwar J, Graves BJ, Cairns BR, Johnson WE. The GNUMAP algorithm: unbiased probabilistic mapping of oligonucleotides from next-generation sequencing. Bioinformatics (Oxford, England). 26: 38-45. PMID 19861355 DOI: 10.1093/Bioinformatics/Btp614 |
0.627 |
|
| 2009 |
Hollenhorst PC, Chandler KJ, Poulsen RL, Johnson WE, Speck NA, Graves BJ. DNA specificity determinants associate with distinct transcription factor functions. Plos Genetics. 5: e1000778. PMID 20019798 DOI: 10.1371/Journal.Pgen.1000778 |
0.797 |
|
| 2009 |
Kang H, Lee G, Nelson M, Graves B, Blaszczak A, McIntosh L. NMR-derived structure of residues 29-138 of murine Ets-1, containing the PNT domain, along with phosphorylated Thr38 and Ser41 Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr16426 |
0.396 |
|
| 2008 |
Lee GM, Pufall MA, Meeker CA, Kang HS, Graves BJ, McIntosh LP. The affinity of Ets-1 for DNA is modulated by phosphorylation through transient interactions of an unstructured region. Journal of Molecular Biology. 382: 1014-30. PMID 18692067 DOI: 10.1016/J.Jmb.2008.07.064 |
0.788 |
|
| 2008 |
Gangwal K, Sankar S, Hollenhorst PC, Kinsey M, Haroldsen SC, Shah AA, Boucher KM, Watkins WS, Jorde LB, Graves BJ, Lessnick SL. Microsatellites as EWS/FLI response elements in Ewing's sarcoma. Proceedings of the National Academy of Sciences of the United States of America. 105: 10149-54. PMID 18626011 DOI: 10.1073/Pnas.0801073105 |
0.729 |
|
| 2008 |
Grenningloh R, Miaw SC, Moisan J, Graves BJ, Ho IC. Role of Ets-1 phosphorylation in the effector function of Th cells. European Journal of Immunology. 38: 1700-5. PMID 18465773 DOI: 10.1002/eji.200738112 |
0.387 |
|
| 2007 |
Hollenhorst PC, Shah AA, Hopkins C, Graves BJ. Genome-wide analyses reveal properties of redundant and specific promoter occupancy within the ETS gene family. Genes & Development. 21: 1882-94. PMID 17652178 DOI: 10.1101/Gad.1561707 |
0.76 |
|
| 2006 |
Macauley MS, Errington WJ, Schärpf M, Mackereth CD, Blaszczak AG, Graves BJ, McIntosh LP. Beads-on-a-string, characterization of ETS-1 sumoylated within its flexible N-terminal sequence. The Journal of Biological Chemistry. 281: 4164-72. PMID 16319071 DOI: 10.1074/Jbc.M510488200 |
0.45 |
|
| 2005 |
Pufall MA, Lee GM, Nelson ML, Kang HS, Velyvis A, Kay LE, McIntosh LP, Graves BJ. Variable control of Ets-1 DNA binding by multiple phosphates in an unstructured region. Science (New York, N.Y.). 309: 142-5. PMID 15994560 DOI: 10.1126/Science.1111915 |
0.745 |
|
| 2005 |
Lee GM, Donaldson LW, Pufall MA, Kang HS, Pot I, Graves BJ, McIntosh LP. The structural and dynamic basis of Ets-1 DNA binding autoinhibition. The Journal of Biological Chemistry. 280: 7088-99. PMID 15591056 DOI: 10.1074/Jbc.M410722200 |
0.742 |
|
| 2004 |
Foulds CE, Nelson ML, Blaszczak AG, Graves BJ. Ras/mitogen-activated protein kinase signaling activates Ets-1 and Ets-2 by CBP/p300 recruitment. Molecular and Cellular Biology. 24: 10954-64. PMID 15572696 DOI: 10.1128/MCB.24.24.10954-10964.2004 |
0.448 |
|
| 2004 |
Hollenhorst PC, Jones DA, Graves BJ. Expression profiles frame the promoter specificity dilemma of the ETS family of transcription factors. Nucleic Acids Research. 32: 5693-702. PMID 15498926 DOI: 10.1093/Nar/Gkh906 |
0.742 |
|
| 2002 |
Garvie CW, Pufall MA, Graves BJ, Wolberger C. Structural analysis of the autoinhibition of Ets-1 and its role in protein partnerships. The Journal of Biological Chemistry. 277: 45529-36. PMID 12221090 DOI: 10.1074/Jbc.M206327200 |
0.744 |
|
| 2002 |
Pufall MA, Graves BJ. Autoinhibitory domains: modular effectors of cellular regulation. Annual Review of Cell and Developmental Biology. 18: 421-62. PMID 12142282 DOI: 10.1146/Annurev.Cellbio.18.031502.133614 |
0.689 |
|
| 2002 |
Pufall MA, Graves BJ. Ets-1 flips for new partner Pax-5. Structure (London, England : 1993). 10: 11-4. PMID 11796106 DOI: 10.1016/S0969-2126(01)00701-8 |
0.738 |
|
| 2002 |
Seidel JJ, Graves BJ. An ERK2 docking site in the Pointed domain distinguishes a subset of ETS transcription factors. Genes & Development. 16: 127-37. PMID 11782450 DOI: 10.1101/Gad.950902 |
0.755 |
|
| 2002 |
Wang H, McIntosh LP, Graves BJ. Inhibitory module of Ets-1 allosterically regulates DNA binding through a dipole-facilitated phosphate contact. The Journal of Biological Chemistry. 277: 2225-33. PMID 11689571 DOI: 10.1074/Jbc.M109430200 |
0.378 |
|
| 2000 |
Cowley DO, Graves BJ. Phosphorylation represses Ets-1 DNA binding by reinforcing autoinhibition Genes and Development. 14: 366-376. PMID 10673508 |
0.458 |
|
| 2000 |
Gu TL, Goetz TL, Graves BJ, Speck NA. Auto-inhibition and partner proteins, core-binding factor beta (CBFbeta) and Ets-1, modulate DNA binding by CBFalpha2 (AML1). Molecular and Cellular Biology. 20: 91-103. PMID 10594012 DOI: 10.1128/Mcb.20.1.91-103.2000 |
0.416 |
|
| 2000 |
Goetz TL, Gu TL, Speck NA, Graves BJ. Auto-inhibition of Ets-1 is counteracted by DNA binding cooperativity with core-binding factor alpha2. Molecular and Cellular Biology. 20: 81-90. PMID 10594011 DOI: 10.1128/Mcb.20.1.81-90.2000 |
0.446 |
|
| 1999 |
Dickinson LA, Trauger JW, Baird EE, Dervan PB, Graves BJ, Gottesfeld JM. Inhibition of Ets-1 DNA binding and ternary complex formation between Ets-1, NF-kappaB, and DNA by a designed DNA-binding ligand. The Journal of Biological Chemistry. 274: 12765-73. PMID 10212261 DOI: 10.1074/jbc.274.18.12765 |
0.437 |
|
| 1998 |
Slupsky CM, Gentile LN, Donaldson LW, Mackereth CD, Seidel JJ, Graves BJ, Mcintosh LP. Structure of the Ets-1 pointed domain and mitogen-activated protein kinase phosphorylation site Proceedings of the National Academy of Sciences of the United States of America. 95: 12129-12134. PMID 9770451 DOI: 10.1073/Pnas.95.21.12129 |
0.737 |
|
| 1998 |
Graves BJ, Petersen JM. Specificity within the ets family of transcription factors Advances in Cancer Research. 75: 1-55. PMID 9709806 |
0.306 |
|
| 1996 |
Graves BJ, Gillespie ME, McIntosh LP. DNA binding by the ETS domain Nature. 384: 322. PMID 8934514 DOI: 10.1038/384322a0 |
0.4 |
|
| 1996 |
Skalicky JJ, Donaldson LW, Petersen JM, Graves BJ, McIntosh LP. Structural coupling of the inhibitory regions flanking the ETS domain of murine Ets-1 Protein Science. 5: 296-309. PMID 8745408 DOI: 10.1002/Pro.5560050214 |
0.449 |
|
| 1996 |
Jonsen MD, Petersen JM, Xu QP, Graves BJ. Characterization of the cooperative function of inhibitory sequences in Ets-1 Molecular and Cellular Biology. 16: 2065-2073. PMID 8628272 |
0.462 |
|
| 1996 |
Donaldson LW, Petersen JM, Graves BJ, McIntosh LP. Solution structure of the ETS domain from murine Ets-1: A winged helix-turn-helix DNA binding motif Embo Journal. 15: 125-134. PMID 8598195 DOI: 10.1002/J.1460-2075.1996.Tb00340.X |
0.433 |
|
| 1995 |
Sun W, Graves BJ, Speck NA. Transactivation of the Moloney murine leukemia virus and T-cell receptor β-chain enhancers by cbf and ets requires intact binding sites for both proteins Journal of Virology. 69: 4941-4949. PMID 7609063 DOI: 10.1128/Jvi.69.8.4941-4949.1995 |
0.405 |
|
| 1994 |
Donaldson LW, Petersen JM, Graves BJ, McIntosh LP. Secondary structure of the ETS domain places murine Ets-1 in the superfamily of winged helix-turn-helix DNA-binding proteins Biochemistry. 33: 13509-13516. PMID 7947760 DOI: 10.1021/Bi00250A001 |
0.438 |
|
| 1994 |
Gunther CV, Graves BJ. Identification of ETS domain proteins in murine T lymphocytes that interact with the Moloney murine leukemia virus enhancer Molecular and Cellular Biology. 14: 7569-7580. PMID 7935472 |
0.469 |
|
| 1993 |
Nelsen B, Tian G, Erman B, Gregoire J, Maki R, Graves B, Sen R. Regulation of lymphoid-specific immunoglobulin mu heavy chain gene enhancer by ETS-domain proteins. Science (New York, N.Y.). 261: 82-6. PMID 8316859 DOI: 10.1126/Science.8316859 |
0.507 |
|
| 1992 |
Nye JA, Petersen JM, Gunther CV, Jonsen MD, Graves BJ. Interaction of murine ets-1 with GGA-binding sites establishes the ETS domain as a new DNA-binding motif. Genes & Development. 6: 975-90. PMID 1592264 |
0.474 |
|
| 1990 |
Gunther CV, Nye JA, Bryner RS, Graves BJ. Sequence-specific DNA binding of the proto-oncoprotein ets-1 defines a transcriptional activator sequence within the long terminal repeat of the Moloney murine sarcoma virus. Genes & Development. 4: 667-79. PMID 2163347 |
0.48 |
|
| 1990 |
Nye JA, Graves BJ. Alkylation interference identifies essential DNA contacts for sequence-specific binding of the eukaryotic transcription factor C/EBP. Proceedings of the National Academy of Sciences of the United States of America. 87: 3992-6. PMID 2160081 |
0.39 |
|
| 1988 |
Landschulz WH, Johnson PF, Adashi EY, Graves BJ, McKnight SL. Isolation of a recombinant copy of the gene encoding C/EBP. Genes & Development. 2: 786-800. PMID 2850264 DOI: 10.1101/Gad.2.7.786 |
0.662 |
|
| 1987 |
Johnson PF, Landschulz WH, Graves BJ, McKnight SL. Identification of a rat liver nuclear protein that binds to the enhancer core element of three animal viruses. Genes & Development. 1: 133-46. PMID 2824279 DOI: 10.1101/Gad.1.2.133 |
0.591 |
|
| 1986 |
Graves BJ, Johnson PF, McKnight SL. Homologous recognition of a promoter domain common to the MSV LTR and the HSV tk gene. Cell. 44: 565-76. PMID 3004739 DOI: 10.1016/0092-8674(86)90266-7 |
0.636 |
|
| 1985 |
Graves BJ, Eisenberg SP, Coen DM, McKnight SL. Alternate utilization of two regulatory domains within the Moloney murine sarcoma virus long terminal repeat. Molecular and Cellular Biology. 5: 1959-68. PMID 3018540 DOI: 10.1128/Mcb.5.8.1959 |
0.546 |
|
| 1985 |
Graves BJ, Eisenman RN, McKnight SL. Delineation of transcriptional control signals within the Moloney murine sarcoma virus long terminal repeat. Molecular and Cellular Biology. 5: 1948-58. PMID 3018539 DOI: 10.1128/Mcb.5.8.1948 |
0.573 |
|
| 1982 |
Graves BJ, Schubiger G. Cell cycle changes during growth and differentiation of imaginal leg discs in Drosophila melanogaster. Developmental Biology. 93: 104-10. PMID 6813162 DOI: 10.1016/0012-1606(82)90243-3 |
0.522 |
|
| 1981 |
Graves B, Schubiger G. Regional differences in the developing foreleg of Drosophila melanogaster. Developmental Biology. 85: 334-43. PMID 6790317 DOI: 10.1016/0012-1606(81)90265-7 |
0.514 |
|
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