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Andrew D. Ellington - Publications

Affiliations: 
1992-1998 Indiana University, Bloomington, Bloomington, IN, United States 
 1998- University of Texas at Austin, Austin, Texas, U.S.A. 
Area:
Nucleic acids and proteins engineering
Website:
https://cns.utexas.edu/directory/item/16-molecular-biosciences/145-ellington-andrew?Itemid=349
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389 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Kosonocky CW, Wilke CO, Marcotte EM, Ellington AD. Mining Patents with Large Language Models Elucidates the Chemical Function Landscape. Arxiv. PMID 38196747  0.471
2023 Goike J, Hsieh CL, Horton AP, Gardner EC, Zhou L, Bartzoka F, Wang N, Javanmardi K, Herbert A, Abbassi S, Xie X, Xia H, Shi PY, Renberg R, Segall-Shapiro TH, ... ... Ellington AD, et al. SARS-COV-2 Omicron variants conformationally escape a rare quaternary antibody binding mode. Communications Biology. 6: 1250. PMID 38082099 DOI: 10.1038/s42003-023-05649-6  0.588
2023 Maier JM, Valenzuela SA, Stok AV, Menta AK, Shimizu Y, Ngo PH, Ellington AD, Anslyn EV. Peptide Macrocyclization Guided by Reversible Covalent Templating. Chemistry (Weinheim An Der Bergstrasse, Germany). e202301949. PMID 37475574 DOI: 10.1002/chem.202301949  0.422
2022 Lee J, Coronado JN, Cho N, Lim J, Hosford BM, Seo S, Kim DS, Kofman C, Moore JS, Ellington AD, Anslyn EV, Jewett MC. Ribosome-mediated biosynthesis of pyridazinone oligomers in vitro. Nature Communications. 13: 6322. PMID 36280685 DOI: 10.1038/s41467-022-33701-2  0.461
2022 Watts E, Thyer R, Ellington AD, Brodbelt JS. Integrated Top-Down and Bottom-Up Mass Spectrometry for Characterization of Diselenide Bridging Patterns of Synthetic Selenoproteins. Analytical Chemistry. PMID 35930618 DOI: 10.1021/acs.analchem.2c01433  0.757
2022 d'Oelsnitz S, Kim W, Burkholder NT, Javanmardi K, Thyer R, Zhang Y, Alper HS, Ellington AD. Using fungible biosensors to evolve improved alkaloid biosyntheses. Nature Chemical Biology. PMID 35799063 DOI: 10.1038/s41589-022-01072-w  0.77
2022 Bean BDM, Mulvihill CJ, Garge RK, Boutz DR, Rousseau O, Floyd BM, Cheney W, Gardner EC, Ellington AD, Marcotte EM, Gollihar JD, Whiteway M, Martin VJJ. Functional expression of opioid receptors and other human GPCRs in yeast engineered to produce human sterols. Nature Communications. 13: 2882. PMID 35610225 DOI: 10.1038/s41467-022-30570-7  0.439
2022 Coronado JN, Ngo P, Anslyn EV, Ellington AD. Chemical insights into flexizyme-mediated tRNA acylation. Cell Chemical Biology. PMID 35413283 DOI: 10.1016/j.chembiol.2022.03.012  0.479
2022 Mackelprang R, Adamala KP, Aurand ER, Diggans JC, Ellington AD, Evans SW, Fortman JLC, Hillson NJ, Hinman AW, Isaacs FJ, Medford JI, Mamaghani S, Moon TS, Palmer MJ, Peccoud J, et al. Making Security Viral: Shifting Engineering Biology Culture and Publishing. Acs Synthetic Biology. 11: 522-527. PMID 35176864 DOI: 10.1021/acssynbio.1c00324  0.621
2022 Shroff R, Ellefson JW, Wang SS, Boulgakov AA, Hughes RA, Ellington AD. Recovery of Information Stored in Modified DNA with an Evolved Polymerase. Acs Synthetic Biology. 11: 554-561. PMID 35113518 DOI: 10.1021/acssynbio.1c00575  0.79
2021 Thyer R, d'Oelsnitz S, Blevins MS, Klein DR, Brodbelt JS, Ellington AD. Directed evolution of an improved aminoacyl-tRNA synthetase for incorporation of L-3,4-dihydroxyphenylalanine (L-DOPA). Angewandte Chemie (International Ed. in English). PMID 33871147 DOI: 10.1002/anie.202100579  0.75
2021 Goike J, Hsieh CL, Horton A, Gardner EC, Bartzoka F, Wang N, Javanmardi K, Herbert A, Abbassi S, Renberg R, Johanson MJ, Cardona JA, Segall-Shapiro T, Zhou L, Nissly RH, ... ... Ellington AD, et al. Synthetic repertoires derived from convalescent COVID-19 patients enable discovery of SARS-CoV-2 neutralizing antibodies and a novel quaternary binding modality. Biorxiv : the Preprint Server For Biology. PMID 33851158 DOI: 10.1101/2021.04.07.438849  0.769
2021 Lee J, Schwarz KJ, Yu H, Krüger A, Anslyn EV, Ellington AD, Moore JS, Jewett MC. Ribosome-mediated incorporation of fluorescent amino acids into peptides . Chemical Communications (Cambridge, England). PMID 33592078 DOI: 10.1039/d0cc07740b  0.456
2020 Akhmetov A, Laurent JM, Gollihar J, Gardner EC, Garge RK, Ellington AD, Kachroo AH, Marcotte EM. Erratum: Correction Notice: Single-step Precision Genome Editing in Yeast Using CRISPR-Cas9. Bio-Protocol. 10. PMID 38161732 DOI: 10.21769/BioProtoc.3610  0.44
2020 Shroff R, Cole AW, Diaz DJ, Morrow BR, Donnell I, Annapareddy A, Gollihar J, Ellington AD, Thyer R. Discovery of Novel Gain-of-Function Mutations Guided by Structure-Based Deep Learning. Acs Synthetic Biology. PMID 33064458 DOI: 10.1021/acssynbio.0c00345  0.754
2020 Van Leuven JT, Ederer MM, Burleigh K, Scott L, Hughes RA, Codrea V, Ellington AD, Wichman H, Miller C. ΦX174 Attenuation by Whole Genome Codon Deoptimization. Genome Biology and Evolution. PMID 33045052 DOI: 10.1093/gbe/evaa214  0.664
2020 Gardner EC, Watkins EJ, Gollihar J, Ellington AD. Emulsion-based directed evolution of enzymes and proteins in yeast. Methods in Enzymology. 643: 87-110. PMID 32896288 DOI: 10.1016/Bs.Mie.2020.04.053  0.345
2020 Choi WS, He P, Pothukuchy A, Gollihar J, Ellington AD, Yang W. How a B family DNA polymerase has been evolved to copy RNA. Proceedings of the National Academy of Sciences of the United States of America. PMID 32817521 DOI: 10.1073/Pnas.2009415117  0.361
2020 Boulgakov AA, Ellington AD, Marcotte EM. Bringing Microscopy-By-Sequencing into View: (Trends in Biotechnology 38, 154-162, 2020). Trends in Biotechnology. 38: 935. PMID 32673590 DOI: 10.1016/J.Tibtech.2020.01.007  0.506
2020 Tanno H, McDaniel JR, Stevens CA, Voss WN, Li J, Durrett R, Lee J, Gollihar J, Tanno Y, Delidakis G, Pothukuchy A, Ellefson JW, Goronzy JJ, Maynard JA, Ellington AD, et al. A facile technology for the high-throughput sequencing of the paired VH:VL and TCRβ:TCRα repertoires. Science Advances. 6: eaay9093. PMID 32426460 DOI: 10.1126/Sciadv.Aay9093  0.784
2020 Lee J, Der BS, Karamitros CS, Li W, Marshall NM, Lungu OI, Miklos AE, Xu J, Kang TH, Lee CH, Tan B, Hughes RA, Jung ST, Ippolito GC, Gray JJ, ... ... Ellington AD, et al. Computer-based Engineering of Thermostabilized Antibody Fragments. Aiche Journal. American Institute of Chemical Engineers. 66. PMID 32336757 DOI: 10.1002/Aic.16864  0.786
2020 Yao D, Bhadra S, Xiong E, Liang H, Ellington AD, Jung C. Dynamic Programming of a DNA Walker Controlled by Protons. Acs Nano. PMID 32167282 DOI: 10.1021/Acsnano.9B08166  0.64
2020 Zamanian-Daryoush M, Gogonea V, DiDonato AJ, Buffa JA, Choucair I, Levison BS, Hughes RA, Ellington AD, Huang Y, Li XS, DiDonato JA, Hazen SL. Site-specific 5-hydroxy-tryptophan incorporation into apolipoprotein A-I impairs cholesterol efflux activity and high density lipoprotein biogenesis. The Journal of Biological Chemistry. PMID 32098873 DOI: 10.1074/Jbc.Ra119.012092  0.675
2020 Le TT, Bruckbauer A, Tahirbegi B, Magness AJ, Ying L, Ellington AD, Cass AEG. A highly stable RNA aptamer probe for the retinoblastoma protein in live cells Chemical Science. 11: 4467-4474. DOI: 10.1039/D0Sc01613F  0.391
2019 Agrawal NK, Allen P, Song YH, Wachs RA, Du Y, Ellington AD, Schmidt CE. Oligonucleotide-functionalized hydrogels for sustained release of small molecule (aptamer) therapeutics. Acta Biomaterialia. PMID 31760222 DOI: 10.1016/J.Actbio.2019.11.037  0.309
2019 Lee J, Schwieter KE, Watkins AM, Kim DS, Yu H, Schwarz KJ, Lim J, Coronado J, Byrom M, Anslyn EV, Ellington AD, Moore JS, Jewett MC. Expanding the limits of the second genetic code with ribozymes. Nature Communications. 10: 5097. PMID 31704912 DOI: 10.1038/S41467-019-12916-W  0.531
2019 Simon AJ, Ellington AD, Finkelstein IJ. Retrons and their applications in genome engineering. Nucleic Acids Research. PMID 31598685 DOI: 10.1093/Nar/Gkz865  0.321
2019 Meinke JL, Simon AJ, Wagner DT, Morrow BR, You S, Ellington AD, Keatinge-Clay AT. Employing 25-Residue Docking Motifs from Modular Polyketide Synthases as Orthogonal Protein Connectors. Acs Synthetic Biology. PMID 31469555 DOI: 10.1021/Acssynbio.9B00047  0.312
2019 Boulgakov AA, Ellington AD, Marcotte EM. Bringing Microscopy-By-Sequencing into View. Trends in Biotechnology. PMID 31416630 DOI: 10.1016/J.Tibtech.2019.06.001  0.527
2019 Wang SS, Ellington AD. Pattern Generation with Nucleic Acid Chemical Reaction Networks. Chemical Reviews. PMID 30865429 DOI: 10.1021/Acs.Chemrev.8B00625  0.344
2019 Hoshika S, Leal NA, Kim MJ, Kim MS, Karalkar NB, Kim HJ, Bates AM, Watkins NE, SantaLucia HA, Meyer AJ, DasGupta S, Piccirilli JA, Ellington AD, SantaLucia J, Georgiadis MM, et al. Hachimoji DNA and RNA: A genetic system with eight building blocks. Science (New York, N.Y.). 363: 884-887. PMID 30792304 DOI: 10.1126/Science.Aat0971  0.796
2019 Park D, Ellington AD, Jung C. Selection of self-priming molecular replicators. Nucleic Acids Research. PMID 30698805 DOI: 10.1093/Nar/Gkz044  0.676
2019 Simon AJ, Zhou Y, Ramasubramani V, Glaser J, Pothukuchy A, Gollihar J, Gerberich JC, Leggere JC, Morrow BR, Jung C, Glotzer SC, Taylor DW, Ellington AD. Supercharging enables organized assembly of synthetic biomolecules. Nature Chemistry. PMID 30643229 DOI: 10.2210/Pdb6Mdr/Pdb  0.668
2018 Bhadra S, Saldaña MA, Han HG, Hughes GL, Ellington AD. Simultaneous Detection of Different Zika Virus Lineages via Molecular Computation in a Point-of-Care Assay. Viruses. 10. PMID 30558136 DOI: 10.3390/V10120714  0.322
2018 Wang B, Thachuk C, Ellington AD, Winfree E, Soloveichik D. Effective design principles for leakless strand displacement systems. Proceedings of the National Academy of Sciences of the United States of America. 115: E12182-E12191. PMID 30545914 DOI: 10.1073/Pnas.1806859115  0.315
2018 Thyer R, Ellington AD. The role of tRNA in Establishing New Genetic Codes. Biochemistry. PMID 30387992 DOI: 10.1021/Acs.Biochem.8B00834  0.782
2018 Akhmetov A, Ellington AD, Marcotte EM. A highly parallel strategy for storage of digital information in living cells. Bmc Biotechnology. 18: 64. PMID 30333005 DOI: 10.1186/S12896-018-0476-4  0.524
2018 Simon AJ, Morrow BR, Ellington AD. Retroelement-based genome editing and evolution. Acs Synthetic Biology. PMID 30256621 DOI: 10.1021/Acssynbio.8B00273  0.336
2018 Garry DJ, Meyer AJ, Ellefson JW, Bull JJ, Ellington AD. Predicting evolution of the transcription regulatory network in a bacteriophage. Genome Biology and Evolution. PMID 30184065 DOI: 10.1093/Gbe/Evy191  0.762
2018 Bhadra S, Riedel TE, Saldaña MA, Hegde S, Pederson N, Hughes GL, Ellington AD. Direct nucleic acid analysis of mosquitoes for high fidelity species identification and detection of Wolbachia using a cellphone. Plos Neglected Tropical Diseases. 12: e0006671. PMID 30161131 DOI: 10.1371/Journal.Pntd.0006671  0.353
2018 Bhadra S, Pothukuchy A, Shroff R, Cole AW, Byrom M, Ellefson JW, Gollihar JD, Ellington AD. Cellular reagents for diagnostics and synthetic biology. Plos One. 13: e0201681. PMID 30110361 DOI: 10.1371/Journal.Pone.0201681  0.773
2018 Abil Z, Ellington AD. Compartmentalized Self-Replication for Evolution of a DNA Polymerase. Current Protocols in Chemical Biology. 10: 1-17. PMID 30040233 DOI: 10.1002/Cpch.34  0.364
2018 Kar S, Ellington AD. Transcription networks based on hairpin promoter switches. Acs Synthetic Biology. PMID 30021064 DOI: 10.1021/Acssynbio.8B00172  0.31
2018 Cai S, Jung C, Bhadra S, Ellington AD. Phosphorothioated primers lead to loop-mediated isothermal amplification at low temperatures. Analytical Chemistry. PMID 29968462 DOI: 10.1021/Acs.Analchem.8B02062  0.679
2018 Garry DJ, Ellington AD, Molineux IJ, Bull JJ. Viral attenuation by engineered protein fragmentation. Virus Evolution. 4: vey017. PMID 29942657 DOI: 10.1093/Ve/Vey017  0.309
2018 Thyer R, Shroff R, Klein DR, d'Oelsnitz S, Cotham VC, Byrom M, Brodbelt JS, Ellington AD. Custom selenoprotein production enabled by laboratory evolution of recoded bacterial strains. Nature Biotechnology. PMID 29863724 DOI: 10.1038/Nbt.4154  0.764
2018 Akhmetov A, Laurent JM, Gollihar J, Gardner EC, Garge RK, Ellington AD, Kachroo AH, Marcotte EM. Single-step Precision Genome Editing in Yeast Using CRISPR-Cas9. Bio-Protocol. 8. PMID 29770349 DOI: 10.21769/BioProtoc.2765  0.504
2018 Baldridge KC, Jora M, Maranhao AC, Quick MM, Addepalli B, Brodbelt JS, Ellington AD, Limbach PA, Contreras LM. Directed Evolution of Heterologous tRNAs Leads to Reduced Dependence on Post-transcriptional Modifications. Acs Synthetic Biology. PMID 29694026 DOI: 10.1021/Acssynbio.7B00421  0.332
2018 Phillips EA, Moehling TJ, Bhadra S, Ellington AD, Linnes JC. Strand displacement probes combined with isothermal nucleic acid amplification for instrument-free detection from complex samples. Analytical Chemistry. PMID 29667809 DOI: 10.1021/Acs.Analchem.8B00269  0.33
2018 Johnson SS, Anslyn EV, Graham HV, Mahaffy PR, Ellington AD. Fingerprinting Non-Terran Biosignatures. Astrobiology. PMID 29634318 DOI: 10.1089/Ast.2017.1712  0.541
2018 Milligan JN, Shroff R, Garry DJ, Ellington AD. Evolution of a Thermophilic Strand-Displacing Polymerase Using High-Temperature Isothermal Compartmentalized Self-Replication. Biochemistry. PMID 29629759 DOI: 10.1021/Acs.Biochem.8B00200  0.319
2018 Ellefson JW, Ledbetter MP, Ellington AD. Directed evolution of a synthetic phylogeny of programmable Trp repressors. Nature Chemical Biology. PMID 29483643 DOI: 10.1038/S41589-018-0006-7  0.771
2018 Tack DS, Cole AC, Shroff R, Morrow BR, Ellington AD. Evolving Bacterial Fitness with an Expanded Genetic Code. Scientific Reports. 8: 3288. PMID 29459649 DOI: 10.1038/S41598-018-21549-W  0.304
2018 d'Oelsnitz S, Ellington A. Continuous directed evolution for strain and protein engineering Current Opinion in Biotechnology. 53: 158-163. PMID 29444489 DOI: 10.1016/J.Copbio.2017.12.020  0.341
2018 Wang B, DeKosky BJ, Timm MR, Lee J, Normandin E, Misasi J, Kong R, McDaniel JR, Delidakis G, Leigh KE, Niezold T, Choi CW, Viox EG, Fahad A, Cagigi A, ... ... Ellington AD, et al. Functional interrogation and mining of natively paired human VH:VL antibody repertoires. Nature Biotechnology. PMID 29309060 DOI: 10.1038/Nbt.4052  0.671
2017 Cammarata M, Thyer R, Lombardo M, Anderson A, Wright D, Ellington A, Brodbelt JS. Characterization of trimethoprim resistant dihydrofolate reductase mutants by mass spectrometry and inhibition by propargyl-linked antifolates. Chemical Science. 8: 4062-4072. PMID 29967675 DOI: 10.1039/C6Sc05235E  0.756
2017 Gade AM, Meadows MK, Ellington AD, Anslyn EV. Differential array sensing for cancer cell classification and novelty detection. Organic & Biomolecular Chemistry. PMID 29139514 DOI: 10.1039/C7Ob02174G  0.487
2017 Abil Z, Ellefson JW, Gollihar JD, Watkins E, Ellington AD. Compartmentalized partnered replication for the directed evolution of genetic parts and circuits. Nature Protocols. 12: 2493-2512. PMID 29120463 DOI: 10.1038/Nprot.2017.119  0.783
2017 Kimoto M, Meyer AJ, Hirao I, Ellington AD. Genetic alphabet expansion transcription generating functional RNA molecules containing a five-letter alphabet including modified unnatural and natural base nucleotides by thermostable T7 RNA polymerase variants. Chemical Communications (Cambridge, England). PMID 29094732 DOI: 10.1039/C7Cc06661A  0.569
2017 Entzminger KC, Hyun JM, Pantazes RJ, Patterson-Orazem AC, Qerqez AN, Frye ZP, Hughes RA, Ellington AD, Lieberman RL, Maranas CD, Maynard JA. De novo design of antibody complementarity determining regions binding a FLAG tetra-peptide. Scientific Reports. 7: 10295. PMID 28860479 DOI: 10.1038/S41598-017-10737-9  0.704
2017 Jung C, Allen PB, Ellington AD. A Simple, Cleated DNA Walker That Hangs on to Surfaces. Acs Nano. PMID 28719175 DOI: 10.1021/Acsnano.7B02693  0.649
2017 Jung C, Hawkins JA, Jones SK, Xiao Y, Rybarski JR, Dillard KE, Hussmann J, Saifuddin FA, Savran CA, Ellington AD, Ke A, Press WH, Finkelstein IJ. Massively Parallel Biophysical Analysis of CRISPR-Cas Complexes on Next Generation Sequencing Chips. Cell. 170: 35-47.e13. PMID 28666121 DOI: 10.1016/J.Cell.2017.05.044  0.684
2017 Jiang YS, Stacy A, Whiteley M, Ellington AD, Bhadra S. Amplicon competition enables end-point quantitation of nucleic acids following isothermal amplification. Chembiochem : a European Journal of Chemical Biology. PMID 28628741 DOI: 10.1002/Cbic.201700317  0.308
2017 Damase TR, Ellington AD, Allen PB. Purification of single-stranded DNA by co-polymerization with acrylamide and electrophoresis. Biotechniques. 62: 275-282. PMID 28625157 DOI: 10.2144/000114557  0.319
2017 Hughes RA, Ellington AD. Synthetic DNA Synthesis and Assembly: Putting the Synthetic in Synthetic Biology. Cold Spring Harbor Perspectives in Biology. 9. PMID 28049645 DOI: 10.1101/Cshperspect.A023812  0.701
2016 Du Y, Pothukuchy A, Gollihar JD, Nourani A, Li B, Ellington AD. Coupling Sensitive Nucleic Acid Amplification with Commercial Pregnancy Test Strips. Angewandte Chemie (International Ed. in English). PMID 27990727 DOI: 10.1002/Anie.201609108  0.631
2016 Lee J, Boutz DR, Chromikova V, Joyce MG, Vollmers C, Leung K, Horton AP, DeKosky BJ, Lee CH, Lavinder JJ, Murrin EM, Chrysostomou C, Hoi KH, Tsybovsky Y, Thomas PV, ... ... Ellington AD, et al. Molecular-level analysis of the serum antibody repertoire in young adults before and after seasonal influenza vaccination. Nature Medicine. PMID 27820605 DOI: 10.1038/Nm.4224  0.587
2016 Zhu Z, Tang Y, Jiang YS, Bhadra S, Du Y, Ellington AD, Li B. Strand-Exchange Nucleic Acid Circuitry with Enhanced Thermo-and Structure- Buffering Abilities Turns Gene Diagnostics Ultra-Reliable and Environmental Compatible. Scientific Reports. 6: 36605. PMID 27812041 DOI: 10.1038/Srep36605  0.63
2016 Maranhao A, Ellington AD. Evolving orthogonal suppressor tRNAs to incorporate modified amino acids. Acs Synthetic Biology. PMID 27600875 DOI: 10.1021/Acssynbio.6B00145  0.349
2016 Singh-Blom A, Hughes RA, Ellington AD. Corrigendum to "An amino acid depleted cell-free protein synthesis system for the incorporation of non-canonical amino acid analogs into proteins" [J. Biotechnol. 178 (2014) 12-22]. Journal of Biotechnology. 231: 296. PMID 27470576 DOI: 10.1016/J.Jbiotec.2016.06.031  0.696
2016 Talukder P, Dedkova LM, Ellington AD, Yakovchuk P, Lim J, Anslyn EV, Hecht SM. Synthesis of alanyl nucleobase amino acids and their incorporation into proteins. Bioorganic & Medicinal Chemistry. PMID 27452282 DOI: 10.1016/J.Bmc.2016.07.008  0.552
2016 Ellefson JW, Gollihar J, Shroff R, Shivram H, Iyer VR, Ellington AD. Synthetic evolutionary origin of a proofreading reverse transcriptase. Science (New York, N.Y.). 352: 1590-3. PMID 27339990 DOI: 10.1126/Science.Aaf5409  0.788
2016 Wang B, Kluwe CA, Lungu OI, DeKosky BJ, Kerr SA, Johnson EL, Tanno H, Lee CH, Jung J, Rezigh AB, Carroll SM, Reyes AN, Bentz JR, Villanueva I, Altman AL, ... ... Ellington AD, et al. Corrigendum: Facile Discovery of a Diverse Panel of Anti-Ebola Virus Antibodies by Immune Repertoire Mining. Scientific Reports. 6: 27229. PMID 27282782 DOI: 10.1038/Srep27229  0.763
2016 Lim J, Lynch VM, Edupuganti R, Ellington A, Anslyn EV. Synthesis and structural analyses of phenylethynyl-substituted tris(2-pyridylmethyl)amines and their copper(ii) complexes. Dalton Transactions (Cambridge, England : 2003). PMID 27264275 DOI: 10.1039/C6Dt00473C  0.46
2016 Wang B, Lee CH, Johnson EL, Kluwe CA, Cunningham JC, Tanno H, Crooks RM, Georgiou G, Ellington AD. Discovery of high affinity anti-ricin antibodies by B cell receptor sequencing and by yeast display of combinatorial VH:VL libraries from immunized animals. Mabs. 0. PMID 27224530 DOI: 10.1080/19420862.2016.1190059  0.464
2016 DeKosky BJ, Lungu OI, Park D, Johnson EL, Charab W, Chrysostomou C, Kuroda D, Ellington AD, Ippolito GC, Gray JJ, Georgiou G. Large-scale sequence and structural comparisons of human naive and antigen-experienced antibody repertoires. Proceedings of the National Academy of Sciences of the United States of America. PMID 27114511 DOI: 10.1073/Pnas.1525510113  0.781
2016 Jung C, Ellington AD. A primerless molecular diagnostic: phosphorothioated-terminal hairpin formation and self-priming extension (PS-THSP). Analytical and Bioanalytical Chemistry. PMID 27032410 DOI: 10.1007/S00216-016-9479-Y  0.679
2016 Cammarata MB, Thyer R, Rosenberg J, Ellington A, Brodbelt JS. Correction to "Structural Characterization of Dihydrofolate Reductase Complexes by Top-Down Ultraviolet Photodissociation Mass Spectrometry". Journal of the American Chemical Society. 138: 3252. PMID 26919090 DOI: 10.1021/Jacs.6B01611  0.756
2016 Martini L, Ellington AD, Mansy SS. An in vitro selection for small molecule induced switching RNA molecules. Methods (San Diego, Calif.). PMID 26899430 DOI: 10.1016/J.Ymeth.2016.02.010  0.692
2016 McDaniel JR, DeKosky BJ, Tanno H, Ellington AD, Georgiou G. Ultra-high-throughput sequencing of the immune receptor repertoire from millions of lymphocytes. Nature Protocols. 11: 429-42. PMID 26844430 DOI: 10.1038/Nprot.2016.024  0.677
2016 Tack DS, Ellefson JW, Thyer R, Wang B, Gollihar J, Forster MT, Ellington AD. Addicting diverse bacteria to a noncanonical amino acid. Nature Chemical Biology. PMID 26780407 DOI: 10.1038/Nchembio.2002  0.778
2016 Du Y, Zhen SJ, Li B, Byrom M, Jiang YS, Ellington AD. Engineering signaling aptamers that rely on kinetic rather than equilibrium competition. Analytical Chemistry. PMID 26750592 DOI: 10.1021/Acs.Analchem.5B03930  0.639
2015 Jung C, Allen PB, Ellington AD. A stochastic DNA walker that traverses a microparticle surface. Nature Nanotechnology. PMID 26524397 DOI: 10.1038/Nnano.2015.246  0.675
2015 Quandt EM, Gollihar J, Blount ZD, Ellington AD, Georgiou G, Barrick JE. Fine-tuning citrate synthase flux potentiates and refines metabolic innovation in the Lenski evolution experiment. Elife. 4. PMID 26465114 DOI: 10.7554/Elife.09696  0.435
2015 Kerr SA, Jackson EL, Lungu OI, Meyer AG, Demogines A, Ellington AD, Georgiou G, Wilke CO, Sawyer SL. Computational and Functional Analysis of the Virus-Receptor Interface Reveals Host Range Trade-Offs in New World Arenaviruses. Journal of Virology. 89: 11643-53. PMID 26355089 DOI: 10.1128/Jvi.01408-15  0.772
2015 Wang B, Kluwe CA, Lungu OI, DeKosky BJ, Kerr SA, Johnson EL, Jung J, Rezigh AB, Carroll SM, Reyes AN, Bentz JR, Villanueva I, Altman AL, Davey RA, Ellington AD, et al. Facile Discovery of a Diverse Panel of Anti-Ebola Virus Antibodies by Immune Repertoire Mining. Scientific Reports. 5: 13926. PMID 26355042 DOI: 10.1038/Srep13926  0.779
2015 Mayfield JE, Fan S, Wei S, Zhang M, Li B, Ellington AD, Etzkorn FA, Zhang YJ. Chemical Tools To Decipher Regulation of Phosphatases by Proline Isomerization on Eukaryotic RNA Polymerase II. Acs Chemical Biology. PMID 26332362 DOI: 10.1021/Acschembio.5B00296  0.354
2015 Meyer AJ, Garry DJ, Hall B, Byrom MM, McDonald HG, Yang X, Yin YW, Ellington AD. Transcription yield of fully 2'-modified RNA can be increased by the addition of thermostabilizing mutations to T7 RNA polymerase mutants. Nucleic Acids Research. PMID 26209133 DOI: 10.1093/Nar/Gkv734  0.642
2015 Jung C, Ellington AD. Synthetic biology: Six pack and stack. Nature Chemistry. 7: 617-9. PMID 26201734 DOI: 10.1038/Nchem.2313  0.68
2015 Cammarata MB, Thyer R, Rosenberg J, Ellington A, Brodbelt JS. Structural Characterization of Dihydrofolate Reductase Complexes by Top-Down Ultraviolet Photodissociation Mass Spectrometry. Journal of the American Chemical Society. 137: 9128-35. PMID 26125523 DOI: 10.1021/Jacs.5B04628  0.762
2015 Du Y, Hughes RA, Bhadra S, Jiang YS, Ellington AD, Li B. A Sweet Spot for Molecular Diagnostics: Coupling Isothermal Amplification and Strand Exchange Circuits to Glucometers. Scientific Reports. 5: 11039. PMID 26050646 DOI: 10.1038/Srep11039  0.783
2015 Allen PB, Khaing Z, Schmidt CE, Ellington AD. 3D Printing with Nucleic Acid Adhesives. Acs Biomaterials Science & Engineering. 1: 19-26. PMID 25984570 DOI: 10.1021/Ab500026F  0.303
2015 Martini L, Meyer AJ, Ellefson JW, Milligan JN, Forlin M, Ellington AD, Mansy SS. In Vitro Selection for Small-Molecule-Triggered Strand Displacement and Riboswitch Activity. Acs Synthetic Biology. PMID 25978303 DOI: 10.1021/Acssynbio.5B00054  0.815
2015 Milligan JN, Ellington AD. Using RecA protein to enhance kinetic rates of DNA circuits. Chemical Communications (Cambridge, England). 51: 9503-6. PMID 25967118 DOI: 10.1039/C5Cc02261D  0.332
2015 Goodwin S, Gade AM, Byrom M, Herrera B, Spears C, Anslyn EV, Ellington AD. Next-generation sequencing as input for chemometrics in differential sensing routines. Angewandte Chemie (International Ed. in English). 54: 6339-42. PMID 25826754 DOI: 10.1002/Anie.201501822  0.528
2015 Ellington AD. RNA as a conception. Rna (New York, N.Y.). 21: 608. PMID 25780159 DOI: 10.1261/Rna.050443.115  0.337
2015 Jiang YS, Bhadra S, Li B, Wu YR, Milligan JN, Ellington AD. Robust strand exchange reactions for the sequence-specific, real-time detection of nucleic acid amplicons. Analytical Chemistry. 87: 3314-20. PMID 25708458 DOI: 10.1021/Ac504387C  0.653
2015 Duclair S, Gautam A, Ellington A, Prasad VR. High-affinity RNA Aptamers Against the HIV-1 Protease Inhibit Both In Vitro Protease Activity and Late Events of Viral Replication. Molecular Therapy. Nucleic Acids. 4: e228. PMID 25689224 DOI: 10.1038/Mtna.2015.1  0.314
2015 Bhadra S, Ellington AD. Design, synthesis, and application of Spinach molecular beacons triggered by strand displacement. Methods in Enzymology. 550: 215-49. PMID 25605388 DOI: 10.1016/Bs.Mie.2014.10.049  0.408
2015 P?osko? E, Wagner SC, Ellington AD, Jewett MC, O'Reilly R, Booth PJ. Controlled assembly of artificial protein-protein complexes via DNA duplex formation. Bioconjugate Chemistry. 26: 427-34. PMID 25603321 DOI: 10.1021/Bc500473S  0.336
2015 Thyer R, Robotham SA, Brodbelt JS, Ellington AD. Evolving tRNA(Sec) for efficient canonical incorporation of selenocysteine. Journal of the American Chemical Society. 137: 46-9. PMID 25521771 DOI: 10.1021/Ja510695G  0.783
2015 DeKosky BJ, Kojima T, Rodin A, Charab W, Ippolito GC, Ellington AD, Georgiou G. In-depth determination and analysis of the human paired heavy- and light-chain antibody repertoire. Nature Medicine. 21: 86-91. PMID 25501908 DOI: 10.1038/Nm.3743  0.48
2014 Stovall GM, Bedenbaugh RS, Singh S, Meyer AJ, Hatala PJ, Ellington AD, Hall B. In vitro selection using modified or unnatural nucleotides. Current Protocols in Nucleic Acid Chemistry / Edited by Serge L. Beaucage ... [Et Al.]. 56: 9.6.1-9.6.33. PMID 25606981 DOI: 10.1002/0471142700.Nc0906S56  0.664
2014 Zamora-Olivares D, Kaoud TS, Jose J, Ellington A, Dalby KN, Anslyn EV. Differential sensing of MAP kinases using SOX-peptides. Angewandte Chemie (International Ed. in English). 53: 14064-8. PMID 25319433 DOI: 10.1002/Anie.201408256  0.436
2014 Meyer AJ, Ellefson JW, Ellington AD. Directed Evolution of a Panel of Orthogonal T7 RNA Polymerase Variants for in Vivo or in Vitro Synthetic Circuitry. Acs Synthetic Biology. PMID 25279711 DOI: 10.1021/Sb500299C  0.773
2014 Segall-Shapiro TH, Meyer AJ, Ellington AD, Sontag ED, Voigt CA. A 'resource allocator' for transcription based on a highly fragmented T7 RNA polymerase. Molecular Systems Biology. 10: 742. PMID 25080493 DOI: 10.15252/Msb.20145299  0.566
2014 Du Y, Lim BJ, Li B, Jiang YS, Sessler JL, Ellington AD. Reagentless, ratiometric electrochemical DNA sensors with improved robustness and reproducibility. Analytical Chemistry. 86: 8010-6. PMID 25010201 DOI: 10.1021/Ac5025254  0.604
2014 Byrom M, Bhadra S, Jiang YS, Ellington AD. Exquisite allele discrimination by toehold hairpin primers. Nucleic Acids Research. 42: e120. PMID 24990378 DOI: 10.1093/Nar/Gku558  0.335
2014 Bhadra S, Ellington AD. A Spinach molecular beacon triggered by strand displacement. Rna (New York, N.Y.). 20: 1183-94. PMID 24942625 DOI: 10.1261/Rna.045047.114  0.418
2014 Jung C, Ellington AD. Diagnostic applications of nucleic acid circuits. Accounts of Chemical Research. 47: 1825-35. PMID 24828239 DOI: 10.1021/Ar500059C  0.683
2014 Melancon MP, Zhou M, Zhang R, Xiong C, Allen P, Wen X, Huang Q, Wallace M, Myers JN, Stafford RJ, Liang D, Ellington AD, Li C. Selective uptake and imaging of aptamer- and antibody-conjugated hollow nanospheres targeted to epidermal growth factor receptors overexpressed in head and neck cancer. Acs Nano. 8: 4530-8. PMID 24754567 DOI: 10.1021/Nn406632U  0.303
2014 Singh-Blom A, Hughes RA, Ellington AD. An amino acid depleted cell-free protein synthesis system for the incorporation of non-canonical amino acid analogs into proteins. Journal of Biotechnology. 178: 12-22. PMID 24631721 DOI: 10.1016/J.Jbiotec.2014.02.009  0.704
2014 Lu WC, Ellington AD. Design and selection of a synthetic operon. Acs Synthetic Biology. 3: 410-5. PMID 24625092 DOI: 10.1021/Sb400160M  0.375
2014 Meyer AG, Sawyer SL, Ellington AD, Wilke CO. Analyzing machupo virus-receptor binding by molecular dynamics simulations. Peerj. 2: e266. PMID 24624315 DOI: 10.7717/Peerj.266  0.304
2014 Meyer AJ, Ellefson JW, Ellington AD. Library generation by gene shuffling. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. 105: Unit 15.12.. PMID 24510437 DOI: 10.1002/0471142727.Mb1512S105  0.752
2014 Bhadra S, Ellington AD. Design and application of cotranscriptional non-enzymatic RNA circuits and signal transducers. Nucleic Acids Research. 42: e58. PMID 24493736 DOI: 10.1093/Nar/Gku074  0.385
2014 O'Connell JD, Tsechansky M, Royall A, Boutz DR, Ellington AD, Marcotte EM. A proteomic survey of widespread protein aggregation in yeast. Molecular Biosystems. 10: 851-61. PMID 24488121 DOI: 10.1039/C3Mb70508K  0.516
2014 Hammerling MJ, Ellefson JW, Boutz DR, Marcotte EM, Ellington AD, Barrick JE. Bacteriophages use an expanded genetic code on evolutionary paths to higher fitness. Nature Chemical Biology. 10: 178-80. PMID 24487692 DOI: 10.1038/Nchembio.1450  0.78
2014 Lavinder JJ, Wine Y, Giesecke C, Ippolito GC, Horton AP, Lungu OI, Hoi KH, DeKosky BJ, Murrin EM, Wirth MM, Ellington AD, Dörner T, Marcotte EM, Boutz DR, Georgiou G. Identification and characterization of the constituent human serum antibodies elicited by vaccination. Proceedings of the National Academy of Sciences of the United States of America. 111: 2259-64. PMID 24469811 DOI: 10.1073/Pnas.1317793111  0.767
2014 Gollihar J, Levy M, Ellington AD. Biochemistry. Many paths to the origin of life. Science (New York, N.Y.). 343: 259-60. PMID 24436411 DOI: 10.1126/Science.1246704  0.483
2014 Zhao A, Tsechansky M, Ellington AD, Marcotte EM. Revisiting and revising the purinosome. Molecular Biosystems. 10: 369-74. PMID 24413256 DOI: 10.1039/C3Mb70397E  0.512
2014 Enyeart PJ, Mohr G, Ellington AD, Lambowitz AM. Biotechnological applications of mobile group II introns and their reverse transcriptases: gene targeting, RNA-seq, and non-coding RNA analysis. Mobile Dna. 5: 2. PMID 24410776 DOI: 10.1186/1759-8753-5-2  0.392
2014 Jiang YS, Bhadra S, Li B, Ellington AD. Mismatches improve the performance of strand-displacement nucleic Acid circuits. Angewandte Chemie (International Ed. in English). 53: 1845-8. PMID 24402831 DOI: 10.1002/Anie.201307418  0.636
2014 Quandt EM, Deatherage DE, Ellington AD, Georgiou G, Barrick JE. Recursive genomewide recombination and sequencing reveals a key refinement step in the evolution of a metabolic innovation in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 111: 2217-22. PMID 24379390 DOI: 10.1073/Pnas.1314561111  0.454
2014 Lu WC, Levy M, Kincaid R, Ellington AD. Directed evolution of the substrate specificity of biotin ligase. Biotechnology and Bioengineering. 111: 1071-81. PMID 24375025 DOI: 10.1002/Bit.25176  0.561
2014 Ellefson JW, Meyer AJ, Hughes RA, Cannon JR, Brodbelt JS, Ellington AD. Directed evolution of genetic parts and circuits by compartmentalized partnered replication. Nature Biotechnology. 32: 97-101. PMID 24185096 DOI: 10.1038/Nbt.2714  0.806
2014 Xu J, Tack D, Hughes RA, Ellington AD, Gray JJ. Structure-based non-canonical amino acid design to covalently crosslink an antibody-antigen complex. Journal of Structural Biology. 185: 215-22. PMID 23680795 DOI: 10.1016/J.Jsb.2013.05.003  0.693
2014 Zamora-Olivares D, Kaoud TS, Jose J, Ellington A, Dalby KN, Anslyn EV. Differential sensing of MAP kinases using SOX-peptides Angewandte Chemie - International Edition. 53: 14064-14068. DOI: 10.1002/anie.201408256  0.348
2013 Chirieleison SM, Allen PB, Simpson ZB, Ellington AD, Chen X. Pattern transformation with DNA circuits. Nature Chemistry. 5: 1000-5. PMID 24256862 DOI: 10.1038/Nchem.1764  0.325
2013 Ledbetter MP, Hwang TW, Stovall GM, Ellington AD. Continuous in vitro evolution of a ribozyme ligase: a model experiment for the evolution of a biomolecule. Biochemistry and Molecular Biology Education : a Bimonthly Publication of the International Union of Biochemistry and Molecular Biology. 41: 433-42. PMID 24214216 DOI: 10.1002/Bmb.20742  0.336
2013 Scida K, Li B, Ellington AD, Crooks RM. DNA detection using origami paper analytical devices. Analytical Chemistry. 85: 9713-20. PMID 24070108 DOI: 10.1021/Ac402118A  0.62
2013 Wilson RH, Morton SK, Deiderick H, Gerth ML, Paul HA, Gerber I, Patel A, Ellington AD, Hunicke-Smith SP, Patrick WM. Engineered DNA ligases with improved activities in vitro. Protein Engineering, Design & Selection : Peds. 26: 471-8. PMID 23754529 DOI: 10.1093/Protein/Gzt024  0.323
2013 Der BS, Kluwe C, Miklos AE, Jacak R, Lyskov S, Gray JJ, Georgiou G, Ellington AD, Kuhlman B. Alternative computational protocols for supercharging protein surfaces for reversible unfolding and retention of stability. Plos One. 8: e64363. PMID 23741319 DOI: 10.1371/Journal.Pone.0064363  0.44
2013 Jiang YS, Li B, Milligan JN, Bhadra S, Ellington AD. Real-time detection of isothermal amplification reactions with thermostable catalytic hairpin assembly. Journal of the American Chemical Society. 135: 7430-3. PMID 23647466 DOI: 10.1021/Ja4023978  0.626
2013 Chen X, Briggs N, McLain JR, Ellington AD. Stacking nonenzymatic circuits for high signal gain. Proceedings of the National Academy of Sciences of the United States of America. 110: 5386-91. PMID 23509255 DOI: 10.1073/Pnas.1222807110  0.315
2013 Singh-Blom A, Hughes RA, Ellington AD. Residue-specific incorporation of unnatural amino acids into proteins in vitro and in vivo. Methods in Molecular Biology (Clifton, N.J.). 978: 93-114. PMID 23423891 DOI: 10.1007/978-1-62703-293-3_7  0.711
2013 Zhao A, Tsechansky M, Swaminathan J, Cook L, Ellington AD, Marcotte EM. Transiently transfected purine biosynthetic enzymes form stress bodies. Plos One. 8: e56203. PMID 23405267 DOI: 10.1371/Journal.Pone.0056203  0.518
2013 Wine Y, Boutz DR, Lavinder JJ, Miklos AE, Hughes RA, Hoi KH, Jung ST, Horton AP, Murrin EM, Ellington AD, Marcotte EM, Georgiou G. Molecular deconvolution of the monoclonal antibodies that comprise the polyclonal serum response. Proceedings of the National Academy of Sciences of the United States of America. 110: 2993-8. PMID 23382245 DOI: 10.1073/Pnas.1213737110  0.767
2013 DeKosky BJ, Ippolito GC, Deschner RP, Lavinder JJ, Wine Y, Rawlings BM, Varadarajan N, Giesecke C, Dörner T, Andrews SF, Wilson PC, Hunicke-Smith SP, Willson CG, Ellington AD, Georgiou G. High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire. Nature Biotechnology. 31: 166-9. PMID 23334449 DOI: 10.1038/Nbt.2492  0.442
2013 Lu WC, Ellington AD. In vitro selection of proteins via emulsion compartments. Methods (San Diego, Calif.). 60: 75-80. PMID 22491026 DOI: 10.1016/J.Ymeth.2012.03.008  0.339
2013 Eckhoff G, Codrea V, Ellington AD, Chen X. Beyond allostery: Catalytic regulation of a deoxyribozyme through an entropy-driven DNA amplifier Journal of Systems Chemistry. 1. DOI: 10.1186/1759-2208-1-13  0.373
2012 Davidson EA, Meyer AJ, Ellefson JW, Levy M, Ellington AD. An in vitro autogene. Acs Synthetic Biology. 1: 190-6. PMID 23651157 DOI: 10.1021/Sb3000113  0.792
2012 Allen PB, Chen X, Ellington AD. Spatial control of DNA reaction networks by DNA sequence. Molecules (Basel, Switzerland). 17: 13390-402. PMID 23143151 DOI: 10.3390/Molecules171113390  0.311
2012 Jiang Y, Li B, Chen X, Ellington AD. Coupling two different nucleic acid circuits in an enzyme-free amplifier. Molecules (Basel, Switzerland). 17: 13211-20. PMID 23132138 DOI: 10.3390/Molecules171113211  0.626
2012 O'Connell JD, Zhao A, Ellington AD, Marcotte EM. Dynamic reorganization of metabolic enzymes into intracellular bodies. Annual Review of Cell and Developmental Biology. 28: 89-111. PMID 23057741 DOI: 10.1146/Annurev-Cellbio-101011-155841  0.511
2012 Opazo F, Levy M, Byrom M, Schäfer C, Geisler C, Groemer TW, Ellington AD, Rizzoli SO. Aptamers as potential tools for super-resolution microscopy. Nature Methods. 9: 938-9. PMID 23018995 DOI: 10.1038/Nmeth.2179  0.473
2012 Li B, Chen X, Ellington AD. Adapting enzyme-free DNA circuits to the detection of loop-mediated isothermal amplification reactions. Analytical Chemistry. 84: 8371-7. PMID 22947054 DOI: 10.1021/Ac301944V  0.648
2012 Cha HJ, Byrom M, Mead PE, Ellington AD, Wallingford JB, Marcotte EM. Evolutionarily repurposed networks reveal the well-known antifungal drug thiabendazole to be a novel vascular disrupting agent. Plos Biology. 10: e1001379. PMID 22927795 DOI: 10.1371/Journal.Pbio.1001379  0.517
2012 Li B, Jiang Y, Chen X, Ellington AD. Probing spatial organization of DNA strands using enzyme-free hairpin assembly circuits. Journal of the American Chemical Society. 134: 13918-21. PMID 22894754 DOI: 10.1021/Ja300984B  0.639
2012 Meyer AJ, Ellefson JW, Ellington AD. Abiotic self-replication. Accounts of Chemical Research. 45: 2097-105. PMID 22891822 DOI: 10.1021/Ar200325V  0.783
2012 Hughes RA, Miklos AE, Ellington AD. Enrichment of error-free synthetic DNA sequences by CEL I nuclease. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit3.24. PMID 22870859 DOI: 10.1002/0471142727.Mb0324S99  0.7
2012 Miklos AE, Hughes RA, Ellington AD. Design and assembly of large synthetic DNA constructs. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit3.23. PMID 22870858 DOI: 10.1002/0471142727.Mb0323S99  0.698
2012 Romero PA, Stone E, Lamb C, Chantranupong L, Krause A, Miklos AE, Hughes RA, Fechtel B, Ellington AD, Arnold FH, Georgiou G. SCHEMA-designed variants of human Arginase I and II reveal sequence elements important to stability and catalysis. Acs Synthetic Biology. 1: 221-8. PMID 22737599 DOI: 10.1021/Sb300014T  0.729
2012 Allen PB, Arshad SA, Li B, Chen X, Ellington AD. DNA circuits as amplifiers for the detection of nucleic acids on a paperfluidic platform. Lab On a Chip. 12: 2951-8. PMID 22729075 DOI: 10.1039/C2Lc40373K  0.643
2012 Ilyas A, Asghar W, Allen PB, Duhon H, Ellington AD, Iqbal SM. Electrical detection of cancer biomarker using aptamers with nanogap break-junctions. Nanotechnology. 23: 275502. PMID 22706642 DOI: 10.1088/0957-4484/23/27/275502  0.327
2012 Zhang M, Wang XJ, Chen X, Bowman ME, Luo Y, Noel JP, Ellington AD, Etzkorn FA, Zhang Y. Structural and kinetic analysis of prolyl-isomerization/phosphorylation cross-talk in the CTD code. Acs Chemical Biology. 7: 1462-70. PMID 22670809 DOI: 10.1021/Cb3000887  0.308
2012 Ippolito GC, Hoi KH, Reddy ST, Carroll SM, Ge X, Rogosch T, Zemlin M, Shultz LD, Ellington AD, Vandenberg CL, Georgiou G. Antibody repertoires in humanized NOD-scid-IL2Rγ(null) mice and human B cells reveals human-like diversification and tolerance checkpoints in the mouse. Plos One. 7: e35497. PMID 22558161 DOI: 10.1371/Journal.Pone.0035497  0.431
2012 Miklos AE, Kluwe C, Der BS, Pai S, Sircar A, Hughes RA, Berrondo M, Xu J, Codrea V, Buckley PE, Calm AM, Welsh HS, Warner CR, Zacharko MA, Carney JP, ... ... Ellington AD, et al. Structure-based design of supercharged, highly thermoresistant antibodies. Chemistry & Biology. 19: 449-55. PMID 22520751 DOI: 10.1016/J.Chembiol.2012.01.018  0.737
2012 Magalhães ML, Byrom M, Yan A, Kelly L, Li N, Furtado R, Palliser D, Ellington AD, Levy M. A general RNA motif for cellular transfection. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 616-24. PMID 22233578 DOI: 10.1038/Mt.2011.277  0.715
2012 Cho EJ, Xia S, Ma LC, Robertus J, Krug RM, Anslyn EV, Montelione GT, Ellington AD. Identification of influenza virus inhibitors targeting NS1A utilizing fluorescence polarization-based high-throughput assay Journal of Biomolecular Screening. 17: 448-459. PMID 22223052 DOI: 10.1177/1087057111431488  0.532
2012 Wan Y, Mahmood MA, Li N, Allen PB, Kim YT, Bachoo R, Ellington AD, Iqbal SM. Nanotextured substrates with immobilized aptamers for cancer cell isolation and cytology. Cancer. 118: 1145-54. PMID 21766299 DOI: 10.1002/Cncr.26349  0.306
2012 Ivy MA, Gallagher LT, Ellington AD, Anslyn EV. Exploration of plasticizer and plastic explosive detection and differentiation with serum albumin cross-reactive arrays Chemical Science. 3: 1773-1779. DOI: 10.1039/C2Sc20083J  0.473
2012 Xu J, Miklos AE, Hughes R, Kuhlman B, Georgiou G, Ellington AD, Gray JJ. A Systematic Computational Method to Predict and Enhance Antibody-Antigen Binding in the Absence of Antibody Crystal Structures Biophysical Journal. 102: 621a. DOI: 10.1016/J.Bpj.2011.11.3382  0.483
2012 Marcotte EM, McGary KK, Ji Cha H, Joo Park T, Woods JO, Blom M, Byrom M, Ellington A, Wallingford JB. Steps Towards a Modular Theory of Disease Biophysical Journal. 102: 9a. DOI: 10.1016/J.Bpj.2011.11.070  0.513
2011 Alicea I, Marvin JS, Miklos AE, Ellington AD, Looger LL, Schreiter ER. Structure of the Escherichia coli phosphonate binding protein PhnD and rationally optimized phosphonate biosensors. Journal of Molecular Biology. 414: 356-69. PMID 22019591 DOI: 10.1016/J.Jmb.2011.09.047  0.327
2011 Reveal B, Garcia C, Ellington A, Macdonald PM. Multiple RNA binding domains of Bruno confer recognition of diverse binding sites for translational repression Rna Biology. 8: 1047-1060. PMID 21955496 DOI: 10.4161/Rna.8.6.17542  0.343
2011 Stewart S, Syrett A, Pothukuchy A, Bhadra S, Ellington A, Anslyn E. Identifying protein variants with cross-reactive aptamer arrays. Chembiochem : a European Journal of Chemical Biology. 12: 2021-4. PMID 21796750 DOI: 10.1002/Cbic.201100046  0.517
2011 Li B, Ellington AD, Chen X. Rational, modular adaptation of enzyme-free DNA circuits to multiple detection methods. Nucleic Acids Research. 39: e110. PMID 21693555 DOI: 10.1093/Nar/Gkr504  0.638
2011 Li N, Nguyen HH, Byrom M, Ellington AD. Inhibition of cell proliferation by an anti-EGFR aptamer. Plos One. 6: e20299. PMID 21687663 DOI: 10.1371/Journal.Pone.0020299  0.309
2011 Meyer AJ, Ellington AD. Molecular evolution picks up the PACE. Nature Biotechnology. 29: 502-3. PMID 21654670 DOI: 10.1038/Nbt.1884  0.317
2011 Hughes RA, Miklos AE, Ellington AD. Gene synthesis: methods and applications. Methods in Enzymology. 498: 277-309. PMID 21601682 DOI: 10.1016/B978-0-12-385120-8.00012-7  0.706
2011 You L, Cho EJ, Leavitt J, Ma LC, Montelione GT, Anslyn EV, Krug RM, Ellington A, Robertus JD. Synthesis and evaluation of quinoxaline derivatives as potential influenza NS1A protein inhibitors. Bioorganic & Medicinal Chemistry Letters. 21: 3007-11. PMID 21478016 DOI: 10.1016/J.Bmcl.2011.03.042  0.47
2011 Hargrove AE, Ellington AD, Anslyn EV, Sessler JL. Chemical functionalization of oligodeoxynucleotides with multiple boronic acids for the polyvalent binding of saccharides. Bioconjugate Chemistry. 22: 388-96. PMID 21299200 DOI: 10.1021/Bc100376X  0.551
2011 Ramalingam D, Duclair S, Datta SA, Ellington A, Rein A, Prasad VR. RNA aptamers directed to human immunodeficiency virus type 1 Gag polyprotein bind to the matrix and nucleocapsid domains and inhibit virus production. Journal of Virology. 85: 305-14. PMID 20980522 DOI: 10.1128/Jvi.02626-09  0.342
2010 Reddy ST, Ge X, Miklos AE, Hughes RA, Kang SH, Hoi KH, Chrysostomou C, Hunicke-Smith SP, Iverson BL, Tucker PW, Ellington AD, Georgiou G. Monoclonal antibodies isolated without screening by analyzing the variable-gene repertoire of plasma cells. Nature Biotechnology. 28: 965-9. PMID 20802495 DOI: 10.1038/Nbt.1673  0.727
2010 Keefe AD, Pai S, Ellington A. Aptamers as therapeutics. Nature Reviews Drug Discovery. 9: 537-550. PMID 20592747 DOI: 10.1038/Nrd3141  0.405
2010 Hughes RA, Ellington AD. Rational design of an orthogonal tryptophanyl nonsense suppressor tRNA. Nucleic Acids Research. 38: 6813-30. PMID 20571084 DOI: 10.1093/Nar/Gkq521  0.697
2010 Chen X, Ellington AD. Shaping up nucleic acid computation. Current Opinion in Biotechnology. 21: 392-400. PMID 20538451 DOI: 10.1016/J.Copbio.2010.05.003  0.305
2010 Wang Y, Khaing ZZ, Li N, Hall B, Schmidt CE, Ellington AD. Aptamer antagonists of myelin-derived inhibitors promote axon growth. Plos One. 5: e9726. PMID 20300533 DOI: 10.1371/Journal.Pone.0009726  0.602
2010 Codrea V, Hayner M, Hall B, Jhaveri S, Ellington A. In vitro selection of RNA aptamers to a small molecule target. Current Protocols in Nucleic Acid Chemistry / Edited by Serge L. Beaucage ... [Et Al.]. Unit 9.5.1-23. PMID 20201029 DOI: 10.1002/0471142700.nc0905s40  0.805
2010 Hall B, Arshad S, Seo K, Bowman C, Corley M, Jhaveri SD, Ellington AD. In vitro selection of RNA aptamers to a protein target by filter immobilization. Current Protocols in Nucleic Acid Chemistry / Edited by Serge L. Beaucage ... [Et Al.]. Unit 9.3.1-27. PMID 20201028 DOI: 10.1002/0471142700.Nc0903S00  0.81
2010 Ge X, Mazor Y, Hunicke-Smith SP, Ellington AD, Georgiou G. Rapid construction and characterization of synthetic antibody libraries without DNA amplification. Biotechnology and Bioengineering. 106: 347-57. PMID 20198660 DOI: 10.1002/Bit.22712  0.508
2010 Lee J, Icoz K, Roberts A, Ellington AD, Savran CA. Diffractometric detection of proteins using microbead-based rolling circle amplification. Analytical Chemistry. 82: 197-202. PMID 19947589 DOI: 10.1021/Ac901716D  0.312
2010 Davidson EA, VAN Blarcom T, Levy M, Ellington AD. Emulsion based selection of T7 promoters of varying activity. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 433-43. PMID 19908395  0.466
2010 Benner SA, Ellington AD. "Progenote" or "protogenote"? Science (New York, N.Y.). 248: 943-4. PMID 17745387 DOI: 10.1126/Science.248.4958.943  0.482
2009 Cho EJ, Lee JW, Ellington AD. Applications of aptamers as sensors. Annual Review of Analytical Chemistry (Palo Alto, Calif.). 2: 241-64. PMID 20636061 DOI: 10.1146/Annurev.Anchem.1.031207.112851  0.392
2009 Chen X, Ellington AD. Design principles for ligand-sensing, conformation-switching ribozymes Plos Computational Biology. 5. PMID 20041206 DOI: 10.1371/Journal.Pcbi.1000620  0.328
2009 Hall B, Micheletti JM, Satya P, Ogle K, Pollard J, Ellington AD. Design, synthesis, and amplification of DNA pools for in vitro selection. Current Protocols in Nucleic Acid Chemistry / Edited by Serge L. Beaucage ... [Et Al.]. Unit 9.2. PMID 20013786 DOI: 10.1002/0471142700.nc0902s39  0.711
2009 Hall B, Arshad S, Seo K, Bowman C, Corley M, Jhaveri SD, Ellington AD. In vitro selection of RNA aptamers to a protein target by filter immobilization. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit 24.3. PMID 19816933 DOI: 10.1002/0471142727.mb2403s88  0.811
2009 Hall B, Micheletti JM, Satya P, Ogle K, Pollard J, Ellington AD. Design, synthesis, and amplification of DNA pools for in vitro selection. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit 24.2. PMID 19816932 DOI: 10.1002/0471142727.Mb2402S88  0.73
2009 Chen X, Denison L, Levy M, Ellington AD. Direct selection for ribozyme cleavage activity in cells. Rna (New York, N.Y.). 15: 2035-45. PMID 19776159 DOI: 10.1261/Rna.1635209  0.559
2009 Hwang TW, Codrea V, Ellington AD. Motifs from the deep. Journal of Biology. 8: 72. PMID 19735583 DOI: 10.1186/Jbiol174  0.329
2009 Davidson EA, Dlugosz PJ, Levy M, Ellington AD. Directed evolution of proteins in vitro using compartmentalization in emulsions. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit 24.6. PMID 19575478 DOI: 10.1002/0471142727.Mb2406S87  0.565
2009 Tabor JJ, Salis HM, Simpson ZB, Chevalier AA, Levskaya A, Marcotte EM, Voigt CA, Ellington AD. A synthetic genetic edge detection program. Cell. 137: 1272-81. PMID 19563759 DOI: 10.1016/J.Cell.2009.04.048  0.72
2009 Narayanaswamy R, Levy M, Tsechansky M, Stovall GM, O'Connell JD, Mirrielees J, Ellington AD, Marcotte EM. Widespread reorganization of metabolic enzymes into reversible assemblies upon nutrient starvation. Proceedings of the National Academy of Sciences of the United States of America. 106: 10147-52. PMID 19502427 DOI: 10.1073/Pnas.0812771106  0.723
2009 Hall B, Cater S, Levy M, Ellington AD. Kinetic optimization of a protein-responsive aptamer beacon. Biotechnology and Bioengineering. 103: 1049-59. PMID 19431189 DOI: 10.1002/Bit.22355  0.723
2009 Piasecki SK, Hall B, Ellington AD. Nucleic acid pool preparation and characterization. Methods in Molecular Biology (Clifton, N.J.). 535: 3-18. PMID 19377997 DOI: 10.1007/978-1-59745-557-2_1  0.654
2009 Ellington AD. Back to the future of nucleic acid self-amplification Nature Chemical Biology. 5: 200-201. PMID 19295523 DOI: 10.1038/Nchembio0409-200  0.305
2009 Seo MJ, Jeong KJ, Leysath CE, Ellington AD, Iverson BL, Georgiou G. Engineering antibody fragments to fold in the absence of disulfide bonds. Protein Science : a Publication of the Protein Society. 18: 259-67. PMID 19177559 DOI: 10.1002/Pro.31  0.472
2009 Pai SS, Ellington AD. Using RNA aptamers and the proximity ligation assay for the detection of cell surface antigens. Methods in Molecular Biology (Clifton, N.J.). 504: 385-98. PMID 19159107 DOI: 10.1007/978-1-60327-569-9_21  0.315
2009 Narayanaswamy R, Moradi EK, Niu W, Hart GT, Davis M, McGary KL, Ellington AD, Marcotte EM. Systematic definition of protein constituents along the major polarization axis reveals an adaptive reuse of the polarization machinery in pheromone-treated budding yeast. Journal of Proteome Research. 8: 6-19. PMID 19053807 DOI: 10.1021/Pr800524G  0.656
2009 Ellington AD, Chen X, Robertson M, Syrett A. Evolutionary origins and directed evolution of RNA International Journal of Biochemistry and Cell Biology. 41: 254-265. PMID 18775793 DOI: 10.1016/J.Biocel.2008.08.015  0.618
2008 Pai S, Roberts A, Ellington AD. Aptamer amplification: divide and signal. Expert Opinion On Medical Diagnostics. 2: 1333-46. PMID 23496781 DOI: 10.1517/17530050802562016  0.359
2008 Gnanam AJ, Hall B, Shen X, Piasecki S, Vernados A, Galyov EE, Smither SJ, Kitto GB, Titball RW, Ellington AD, Brown KA. Development of aptamers specific for potential diagnostic targets in Burkholderia pseudomallei. Transactions of the Royal Society of Tropical Medicine and Hygiene. 102: S55-7. PMID 19121689 DOI: 10.1016/S0035-9203(08)70015-4  0.653
2008 Fan S, Wu F, Martiniuk F, Hale ML, Ellington AD, Tchou-Wong KM. Protective effects of anti-ricin A-chain RNA aptamer against ricin toxicity. World Journal of Gastroenterology : Wjg. 14: 6360-5. PMID 19009652 DOI: 10.3748/Wjg.14.6360  0.337
2008 Paukstelis PJ, Ellington AD. Rolling out DNA nanostructures in vivo. Proceedings of the National Academy of Sciences of the United States of America. 105: 17593-4. PMID 19008359 DOI: 10.1073/Pnas.0810029105  0.332
2008 Levy M, Ellington AD. Directed evolution of streptavidin variants using in vitro compartmentalization. Chemistry & Biology. 15: 979-89. PMID 18804035 DOI: 10.1016/J.Chembiol.2008.07.017  0.57
2008 Yan A, Ellington A. A hitchhiker's guide to HIV Molecular Therapy. 16: 1356-1358. PMID 18660800 DOI: 10.1038/Mt.2008.131  0.533
2008 Cowperthwaite MC, Ellington AD. Bioinformatic analysis of the contribution of primer sequences to aptamer structures. Journal of Molecular Evolution. 67: 95-102. PMID 18594898 DOI: 10.1007/S00239-008-9130-4  0.37
2008 Tabor JJ, Bayer TS, Simpson ZB, Levy M, Ellington AD. Engineering stochasticity in gene expression. Molecular Biosystems. 4: 754-61. PMID 18563250 DOI: 10.1039/B801245H  0.649
2008 Yang L, Ellington AD. Real-time PCR detection of protein analytes with conformation-switching aptamers. Analytical Biochemistry. 380: 164-73. PMID 18541130 DOI: 10.1016/J.Ab.2008.05.018  0.581
2008 Javier DJ, Nitin N, Levy M, Ellington A, Richards-Kortum R. Aptamer-targeted gold nanoparticles as molecular-specific contrast agents for reflectance imaging. Bioconjugate Chemistry. 19: 1309-12. PMID 18512972 DOI: 10.1021/Bc8001248  0.5
2008 Ellington A, Chory J. Deprotection of oligonucleotides and purification using denaturing PAGE. Current Protocols in Immunology. Unit 10.7. PMID 18432699 DOI: 10.1002/0471142735.Im1007S06  0.352
2008 Hughes AD, Glenn IC, Patrick AD, Ellington A, Anslyn EV. A pattern recognition based fluorescence quenching assay for the detection and identification of nitrated explosive analytes. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 1822-7. PMID 18161712 DOI: 10.1002/Chem.200701546  0.474
2008 Rajendran M, Ellington AD. Selection of fluorescent aptamer beacons that light up in the presence of zinc. Analytical and Bioanalytical Chemistry. 390: 1067-75. PMID 18049815 DOI: 10.1007/S00216-007-1735-8  0.625
2008 Cho EJ, Lee JW, Rajendran M, Ellington AD. Nucleic acids for reagentless biosensors Optical Biosensors. 493-541. DOI: 10.1016/B978-044453125-4.50015-2  0.553
2007 Chen X, Li N, Ellington AD. Ribozyme catalysis of metabolism in the RNA world Chemistry and Biodiversity. 4: 633-655. PMID 17443876 DOI: 10.1002/Cbdv.200790055  0.371
2007 Yang L, Fung CW, Cho EJ, Ellington AD. Real-time rolling circle amplification for protein detection. Analytical Chemistry. 79: 3320-9. PMID 17378540 DOI: 10.1021/Ac062186B  0.592
2007 Davidson EA, Ellington AD. Synthetic RNA circuits Nature Chemical Biology. 3: 23-28. PMID 17173026 DOI: 10.1038/Nchembio846  0.345
2007 Sokolov K, Nida D, Descour M, Lacy A, Levy M, Hall B, Dharmawardhane S, Ellington A, Korgel B, Richards-Kortum R. Molecular optical imaging of therapeutic targets of cancer. Advances in Cancer Research. 96: 299-344. PMID 17161684 DOI: 10.1016/S0065-230X(06)96011-4  0.486
2007 Bacher JM, Ellington AD. Global incorporation of unnatural amino acids in Escherichia coli Methods in Molecular Biology (Clifton, N.J.). 352: 23-34. PMID 17041257 DOI: 10.1385/1-59745-187-8:23  0.322
2007 Hall B, Hesselberth JR, Ellington AD. Computational selection of nucleic acid biosensors via a slip structure model. Biosensors & Bioelectronics. 22: 1939-47. PMID 16996258 DOI: 10.1016/J.Bios.2006.08.019  0.754
2007 Sooter LJ, Gates-Shannon P, Ellington AD. Automated Assessment of the DNA-Binding Capacity of a Proteome by In Vitro Selection Jala - Journal of the Association For Laboratory Automation. 12: 135-142. DOI: 10.1016/J.Jala.2007.02.003  0.756
2006 Tabor JJ, Davidson EA, Ellington AD. Developing RNA tools for engineered regulatory systems. Biotechnology & Genetic Engineering Reviews. 22: 21-44. PMID 18476324 DOI: 10.1080/02648725.2006.10648063  0.577
2006 Cho EJ, Collett JR, Szafranska AE, Ellington AD. Optimization of aptamer microarray technology for multiple protein targets. Analytica Chimica Acta. 564: 82-90. PMID 17723365 DOI: 10.1016/J.Aca.2005.12.038  0.735
2006 Knudsen SM, Lee J, Ellington AD, Savran CA. Ribozyme-mediated signal augmentation on a mass-sensitive biosensor. Journal of the American Chemical Society. 128: 15936-7. PMID 17165697 DOI: 10.1021/Ja064137M  0.648
2006 Garibotti AV, Knudsen SM, Ellington AD, Seeman NC. Functional DNAzymes organized into two-dimensional arrays. Nano Letters. 6: 1505-7. PMID 16834439 DOI: 10.1021/Nl0609955  0.649
2006 Chu TC, Marks JW, Lavery LA, Faulkner S, Rosenblum MG, Ellington AD, Levy M. Aptamer:toxin conjugates that specifically target prostate tumor cells. Cancer Research. 66: 5989-92. PMID 16778167 DOI: 10.1158/0008-5472.Can-05-4583  0.507
2006 Chu TC, Twu KY, Ellington AD, Levy M. Aptamer mediated siRNA delivery. Nucleic Acids Research. 34: e73. PMID 16740739 DOI: 10.1093/Nar/Gkl388  0.526
2006 Tabor JJ, Levy M, Ellington AD. Deoxyribozymes that recode sequence information. Nucleic Acids Research. 34: 2166-72. PMID 16648360 DOI: 10.1093/Nar/Gkl176  0.703
2006 Lee JF, Stovall GM, Ellington AD. Aptamer therapeutics advance Current Opinion in Chemical Biology. 10: 282-289. PMID 16621675 DOI: 10.1016/J.Cbpa.2006.03.015  0.523
2006 Narayanaswamy R, Ellington AD. Engineering RNA-based circuits. Handbook of Experimental Pharmacology. 423-45. PMID 16594629 DOI: 10.1007/3-540-27262-3_22  0.587
2006 Narayanaswamy R, Niu W, Scouras AD, Hart GT, Davies J, Ellington AD, Iyer VR, Marcotte EM. Systematic profiling of cellular phenotypes with spotted cell microarrays reveals mating-pheromone response genes. Genome Biology. 7: R6. PMID 16507139 DOI: 10.1186/Gb-2006-7-1-R6  0.659
2006 Chu TC, Shieh F, Lavery LA, Levy M, Richards-Kortum R, Korgel BA, Ellington AD. Labeling tumor cells with fluorescent nanocrystal-aptamer bioconjugates. Biosensors & Bioelectronics. 21: 1859-66. PMID 16495043 DOI: 10.1016/J.Bios.2005.12.015  0.52
2006 Ellington AD, Cox JC, Lee JF, Collett JR. 24 Automated In Vitro Selection and Microarray Applications for Functional RNA Sequences Cold Spring Harbor Monograph Archive. 43: 683-719. DOI: 10.1101/087969739.43.683  0.732
2006 Cho EJ, Collett JR, Szafranska AE, Ellington AD. Optimization of aptamer microarray technology for multiple protein targets Analytica Chimica Acta. 564: 82-90. DOI: 10.1016/j.aca.2005.12.038  0.683
2006 Knudsen SM, Ellington AD. Aptazymes: Allosteric Ribozymes and Deoxyribozymes as Biosensors The Aptamer Handbook: Functional Oligonucleotides and Their Applications. 290-310. DOI: 10.1002/3527608192.ch13  0.663
2005 Bayer TS, Booth LN, Knudsen SM, Ellington AD. Arginine-rich motifs present multiple interfaces for specific binding by RNA. Rna (New York, N.Y.). 11: 1848-57. PMID 16314457 DOI: 10.1261/Rna.2167605  0.713
2005 Levskaya A, Chevalier AA, Tabor JJ, Simpson ZB, Lavery LA, Levy M, Davidson EA, Scouras A, Ellington AD, Marcotte EM, Voigt CA. Synthetic biology: engineering Escherichia coli to see light. Nature. 438: 441-2. PMID 16306980 DOI: 10.1038/Nature04405  0.759
2005 Levy M, Cater SF, Ellington AD. Quantum-dot aptamer beacons for the detection of proteins. Chembiochem : a European Journal of Chemical Biology. 6: 2163-6. PMID 16254932 DOI: 10.1002/Cbic.200500218  0.473
2005 Bryant KF, Cox JC, Wang H, Hogle JM, Ellington AD, Coen DM. Binding of herpes simplex virus-1 US11 to specific RNA sequences. Nucleic Acids Research. 33: 6090-100. PMID 16246910 DOI: 10.1093/Nar/Gki919  0.386
2005 Pai S, Ellington AD, Levy M. Proximity ligation assays with peptide conjugate 'burrs' for the sensitive detection of spores. Nucleic Acids Research. 33: e162. PMID 16237122 DOI: 10.1093/Nar/Gni150  0.521
2005 Keller KM, Breeden MM, Zhang J, Ellington AD, Brodbelt JS. Electrospray ionization of nucleic acid aptamer/small molecule complexes for screening aptamer selectivity. Journal of Mass Spectrometry : Jms. 40: 1327-37. PMID 16217837 DOI: 10.1002/Jms.915  0.304
2005 Collett JR, Eun JC, Ellington AD. Production and processing of aptamer microarrays Methods. 37: 4-15. PMID 16199170 DOI: 10.1016/J.Ymeth.2005.05.009  0.752
2005 Levy M, Griswold KE, Ellington AD. Direct selection of trans-acting ligase ribozymes by in vitro compartmentalization. Rna (New York, N.Y.). 11: 1555-62. PMID 16131588 DOI: 10.1261/Rna.2121705  0.551
2005 Flores H, Ellington AD. A modified consensus approach to mutagenesis inverts the cofactor specificity of Bacillus stearothermophilus lactate dehydrogenase Protein Engineering Design & Selection. 18: 369-377. PMID 16012175 DOI: 10.1093/Protein/Gzi043  0.313
2005 Yan AC, Bell KM, Breeden MM, Ellington AD. Aptamers: prospects in therapeutics and biomedicine. Frontiers in Bioscience : a Journal and Virtual Library. 10: 1802-27. PMID 15769669 DOI: 10.2741/1663  0.632
2005 Davidson EA, Ellington AD. Engineering regulatory RNAs. Trends in Biotechnology. 23: 109-112. PMID 15734551 DOI: 10.1016/J.Tibtech.2005.01.006  0.355
2005 Cho EJ, Yang L, Levy M, Ellington AD. Using a deoxyribozyme ligase and rolling circle amplification to detect a non-nucleic acid analyte, ATP. Journal of the American Chemical Society. 127: 2022-3. PMID 15713061 DOI: 10.1021/Ja043490U  0.653
2005 Collett JR, Cho EJ, Lee JF, Levy M, Hood AJ, Wan C, Ellington AD. Functional RNA microarrays for high-throughput screening of antiprotein aptamers. Analytical Biochemistry. 338: 113-23. PMID 15707941 DOI: 10.1016/J.Ab.2004.11.027  0.812
2005 Hughes RA, Ellington AD. Mistakes in translation don't translate into termination. Proceedings of the National Academy of Sciences of the United States of America. 102: 1273-4. PMID 15677335 DOI: 10.1073/Pnas.0409443101  0.694
2005 Lee JF, Cox JC, Collett JR, Ellington AD. Exploring sequence space through automated aptamer selection Jala - Journal of the Association For Laboratory Automation. 10: 213-218. DOI: 10.1016/J.Jala.2005.05.004  0.787
2004 Bacher JM, Hughes RA, Tze-Fei Wong J, Ellington AD. Evolving new genetic codes. Trends in Ecology & Evolution. 19: 69-75. PMID 16701231 DOI: 10.1016/J.Tree.2003.11.007  0.692
2004 Manimala JC, Wiskur SL, Ellington AD, Anslyn EV. Tuning the specificity of a synthetic receptor using a selected nucleic acid receptor Journal of the American Chemical Society. 126: 16515-16519. PMID 15600355 DOI: 10.1021/Ja0478476  0.797
2004 Hughes RA, Robertson MP, Ellington AD, Levy M. The importance of prebiotic chemistry in the RNA world. Current Opinion in Chemical Biology. 8: 629-33. PMID 15556407 DOI: 10.1016/J.Cbpa.2004.09.007  0.802
2004 Meyers LA, Lee JF, Cowperthwaite M, Ellington AD. The robustness of naturally and artificially selected nucleic acid secondary structures Journal of Molecular Evolution. 58: 681-691. PMID 15461425 DOI: 10.1007/S00239-004-2590-2  0.537
2004 Chelliserrykattil J, Ellington AD. Evolution of a T7 RNA polymerase variant that transcribes 2'-O-methyl RNA. Nature Biotechnology. 22: 1155-1160. PMID 15300257 DOI: 10.1038/Nbt1001  0.378
2004 Kirby R, Cho EJ, Gehrke B, Bayer T, Park YS, Neikirk DP, McDevitt JT, Ellington AD. Aptamer-based sensor arrays for the detection and quantitation of proteins. Analytical Chemistry. 76: 4066-75. PMID 15253644 DOI: 10.1021/Ac049858N  0.579
2004 Savran CA, Knudsen SM, Ellington AD, Manalis SR. Micromechanical detection of proteins using aptamer-based receptor molecules. Analytical Chemistry. 76: 3194-8. PMID 15167801 DOI: 10.1021/Ac049859F  0.669
2004 Knudsen SM, Ellington AD. Ribozyme déjà vu. Nature Structural & Molecular Biology. 11: 301-3. PMID 15048102 DOI: 10.1038/Nsmb0404-301  0.673
2004 Robertson MP, Knudsen SM, Ellington AD. In vitro selection of ribozymes dependent on peptides for activity. Rna (New York, N.Y.). 10: 114-27. PMID 14681590 DOI: 10.1261/Rna.5900204  0.741
2004 Hoffman MM, Khrapov MA, Cox JC, Yao J, Tong L, Ellington AD. AANT: the Amino Acid-Nucleotide Interaction Database. Nucleic Acids Research. 32: D174-81. PMID 14681388 DOI: 10.1093/Nar/Gkh128  0.309
2004 Lee JF, Hesselberth JR, Meyers LA, Ellington AD. Aptamer database. Nucleic Acids Research. 32: D95-100. PMID 14681367 DOI: 10.1093/nar/gkh094  0.674
2004 Meiring JE, Schmid MJ, Grayson SM, Rathsack BM, Johnson DM, Kirby R, Kannappan R, Manthiram K, Hsia B, Hogan ZL, Ellington AD, Pishko MV, Willson CG. Hydrogel biosensor array platform indexed by shape Chemistry of Materials. 16: 5574-5580. DOI: 10.1021/Cm049488J  0.558
2004 Sooter LJ, Ellington AD. Automated selection of transcription factor binding sites Jala - Journal of the Association For Laboratory Automation. 9: 277-284. DOI: 10.1016/J.Jala.2004.05.004  0.746
2004 Stovall GM, Cox JC, Ellington AD. Automated optimization of Aptamer selection buffer conditions Jala - Journal of the Association For Laboratory Automation. 9: 117-122. DOI: 10.1016/J.Jala.2004.04.010  0.328
2004 Goertz PW, Cox JC, Ellington AD. Automated selection of aminoglycoside aptamers Jala - Journal of the Association For Laboratory Automation. 9: 150-154. DOI: 10.1016/J.Jala.2004.04.008  0.342
2003 Ali MF, Kirby R, Goodey AP, Rodriguez MD, Ellington AD, Neikirk DP, McDevitt JT. DNA hybridization and discrimination of single-nucleotide mismatches using chip-based microbead arrays. Analytical Chemistry. 75: 4732-9. PMID 14674448 DOI: 10.1021/Ac034106Z  0.608
2003 Bacher JM, Bull JJ, Ellington AD. Evolution of phage with chemically ambiguous proteomes. Bmc Evolutionary Biology. 3: 24. PMID 14667253 DOI: 10.1186/1471-2148-3-24  0.344
2003 Rajendran M, Ellington AD. In vitro selection of molecular beacons. Nucleic Acids Research. 31: 5700-13. PMID 14500834 DOI: 10.1093/Nar/Gkg764  0.661
2003 Tabor JJ, Ellington AD. Playing to win at DNA computation. Nature Biotechnology. 21: 1013-5. PMID 12949563 DOI: 10.1038/Nbt0903-1013  0.553
2003 Levy M, Ellington AD. Exponential growth by cross-catalytic cleavage of deoxyribozymogens. Proceedings of the National Academy of Sciences of the United States of America. 100: 6416-21. PMID 12743371 DOI: 10.1073/Pnas.1130145100  0.552
2003 Levy M, Ellington AD. Peptide-templated nucleic acid ligation. Journal of Molecular Evolution. 56: 607-15. PMID 12698297 DOI: 10.1007/S00239-002-2429-7  0.537
2003 Hesselberth JR, Robertson MP, Knudsen SM, Ellington AD. Simultaneous detection of diverse analytes with an aptazyme ligase array. Analytical Biochemistry. 312: 106-12. PMID 12531194 DOI: 10.1016/S0003-2697(02)00441-4  0.786
2003 Hall B, Ellington AD. Survival and polymerase chain reaction-based detection of nucleic acid taggant markers during bacterial growth and sterilization Analytica Chimica Acta. 475: 67-73. DOI: 10.1016/S0003-2670(02)01034-6  0.625
2002 Knudsen SM, Robertson MP, Ellington AD. In vitro selection using modified or unnatural nucleotides. Current Protocols in Nucleic Acid Chemistry / Edited by Serge L. Beaucage ... [Et Al.]. Unit 9.6. PMID 18428900 DOI: 10.1002/0471142700.Nc0906S07  0.777
2002 Jhaveri S, Ellington A. In vitro selection of RNA aptamers to a small molecule target Current Protocols in Nucleic Acid Chemistry / Edited by Serge L. Beaucage ... [Et Al.]. PMID 18428899 DOI: 10.1002/0471142700.Nc0905S08  0.783
2002 Yang X, Bassett SE, Li X, Luxon BA, Herzog NK, Shope RE, Aronson J, Prow TW, Leary JF, Kirby R, Ellington AD, Gorenstein DG. Construction and selection of bead-bound combinatorial oligonucleoside phosphorothioate and phosphorodithioate aptamer libraries designed for rapid PCR-based sequencing. Nucleic Acids Research. 30: e132. PMID 12466564 DOI: 10.1093/Nar/Gnf132  0.627
2002 Thompson KM, Syrett HA, Knudsen SM, Ellington AD. Group I aptazymes as genetic regulatory switches. Bmc Biotechnology. 2: 21. PMID 12466025 DOI: 10.1186/1472-6750-2-21  0.66
2002 Hesselberth JR, Ellington AD. A (ribo) switch in the paradigms of genetic regulation. Nature Structural Biology. 9: 891-3. PMID 12447352 DOI: 10.1038/Nsb1202-891  0.635
2002 Cox JC, Hayhurst A, Hesselberth J, Bayer TS, Georgiou G, Ellington AD. Automated selection of aptamers against protein targets translated in vitro: from gene to aptamer. Nucleic Acids Research. 30: e108. PMID 12384610 DOI: 10.1093/Nar/Gnf107  0.729
2002 Sooter LJ, Ellington AD. Reflections on a novel therapeutic candidate. Chemistry & Biology. 9: 857-8. PMID 12204684 DOI: 10.1016/S1074-5521(02)00190-4  0.74
2002 Bacher JM, Reiss BD, Ellington AD. Anticipatory evolution and DNA shuffling. Genome Biology. 3: REVIEWS1021. PMID 12186650 DOI: 10.1186/Gb-2002-3-8-Reviews1021  0.316
2002 Yan A, Ellington AD. Aptamers as potential diagnostic reagents for diabetes Diabetes Technology and Therapeutics. 4: 339-346. PMID 12165173 DOI: 10.1089/152091502760098483  0.67
2002 Hartig JS, Najafi-Shoushtari SH, Grüne I, Yan A, Ellington AD, Famulok M. Protein-dependent ribozymes report molecular interactions in real time. Nature Biotechnology. 20: 717-22. PMID 12089558 DOI: 10.1038/Nbt0702-717  0.706
2002 Cox JC, Rajendran M, Riedel T, Davidson EA, Sooter LJ, Bayer TS, Schmitz-Brown M, Ellington AD. Automated acquisition of aptamer sequences. Combinatorial Chemistry & High Throughput Screening. 5: 289-99. PMID 12052180 DOI: 10.2174/1386207023330291  0.808
2002 Rajendran M, Ellington AD. Selecting nucleic acids for biosensor applications. Combinatorial Chemistry & High Throughput Screening. 5: 263-70. PMID 12052178 DOI: 10.2174/1386207023330246  0.657
2002 Levy M, Ellington AD. ATP-dependent allosteric DNA enzymes. Chemistry & Biology. 9: 417-26. PMID 11983331 DOI: 10.1016/S1074-5521(02)00123-0  0.561
2002 Levy M, Ellington AD. In vitro selection of a deoxyribozyme that can utilize multiple substrates. Journal of Molecular Evolution. 54: 180-90. PMID 11821911 DOI: 10.1007/S00239-001-0066-1  0.553
2002 Matsumura I, Ellington AD. Mutagenic polymerase chain reaction of protein-coding genes for in vitro evolution. Methods in Molecular Biology (Clifton, N.J.). 182: 259-67. PMID 11768971 DOI: 10.1385/1-59259-194-9:259  0.665
2001 Pollard J, Bell SD, Ellington AD. Design, synthesis, and amplification of DNA pools for in vitro selection. Current Protocols in Nucleic Acid Chemistry / Edited by Serge L. Beaucage ... [Et Al.]. Unit 9.2. PMID 18428880 DOI: 10.1002/0471142700.Nc0902S00  0.592
2001 Ellington A, Pollard JD. Introduction to the synthesis and purification of oligonucleotides. Current Protocols in Nucleic Acid Chemistry / Edited by Serge L. Beaucage ... [Et Al.]. Appendix 3C. PMID 18428812 DOI: 10.1002/0471142700.Nca03Cs00  0.602
2001 Jhaveri SD, Ellington AD. In vitro selection of RNA aptamers to a protein target by filter immobilization Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. PMID 18265210 DOI: 10.1002/0471142727.Mb2403S52  0.786
2001 Pollard J, Bell SD, Ellington AD. Design, synthesis, and amplification of DNA pools for construction of combinatorial pools and libraries. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit 24.2. PMID 18265209 DOI: 10.1002/0471142727.Mb2402S52  0.599
2001 Ellington A, Pollard JD. Purification of oligonucleotides using denaturing polyacrylamide gel electrophoresis. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit2.12. PMID 18265180 DOI: 10.1002/0471142727.Mb0212S42  0.574
2001 Ellington A, Pollard JD. Synthesis and purification of oligonucleotides. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit2.11. PMID 18265179 DOI: 10.1002/0471142727.Mb0211S42  0.616
2001 Chelliserrykattil J, Cai G, Ellington AD. A combined in vitro / in vivo selection for polymerases with novel promoter specificities Bmc Biotechnology. 1: 13-13. PMID 11806761 DOI: 10.1186/1472-6750-1-13  0.378
2001 Sooter LJ, Riedel T, Davidson EA, Levy M, Cox JC, Ellington AD. Toward automated nucleic acid enzyme selection. Biological Chemistry. 382: 1327-34. PMID 11688716 DOI: 10.1515/Bc.2001.165  0.792
2001 Levy M, Ellington AD. Selection of deoxyribozyme ligases that catalyze the formation of an unnatural internucleotide linkage. Bioorganic & Medicinal Chemistry. 9: 2581-7. PMID 11557346 DOI: 10.1016/S0968-0896(01)00033-5  0.546
2001 Cox JC, Ellington AD. Automated selection of anti-protein aptamers. Bioorganic & Medicinal Chemistry. 9: 2525-31. PMID 11557339 DOI: 10.1016/S0968-0896(01)00028-1  0.374
2001 Levy M, Ellington AD. RNA world: catalysis abets binding, but not vice versa. Current Biology : Cb. 11: R665-7. PMID 11525762 DOI: 10.1016/S0960-9822(01)00388-8  0.551
2001 Bacher JM, Ellington AD. Selection and characterization of Escherichia coli variants capable of growth on an otherwise toxic tryptophan analogue. Journal of Bacteriology. 183: 5414-5425. PMID 11514527 DOI: 10.1128/Jb.183.18.5414-5425.2001  0.316
2001 Hamaguchi N, Ellington A, Stanton M. Aptamer beacons for the direct detection of proteins. Analytical Biochemistry. 294: 126-31. PMID 11444807 DOI: 10.1006/Abio.2001.5169  0.34
2001 Robertson MP, Ellington AD. In vitro selection of nucleoprotein enzymes. Nature Biotechnology. 19: 650-5. PMID 11433277 DOI: 10.1038/90256  0.618
2001 Levy M, Ellington AD. The descent of polymerization. Nature Structural Biology. 8: 580-2. PMID 11427883 DOI: 10.1038/89601  0.542
2001 Robertson MP, Hesselberth JR, Ellington AD. Optimization and optimality of a short ribozyme ligase that joins non-Watson-Crick base pairings. Rna (New York, N.Y.). 7: 513-23. PMID 11345430 DOI: 10.1017/S1355838201002199  0.725
2001 Hoffman D, Hesselberth J, Ellington AD. Switching nucleic acids for antibodies. Nature Biotechnology. 19: 313-4. PMID 11283579 DOI: 10.1038/86678  0.626
2001 Matsumura I, Olsen MJ, Ellington AD. Optimization of heterologous gene expression for in vitro evolution. Biotechniques. 30: 474-6. PMID 11252780 DOI: 10.2144/01303Bm01  0.64
2001 Matsumura I, Ellington AD. In vitro evolution of beta-glucuronidase into a beta-galactosidase proceeds through non-specific intermediates. Journal of Molecular Biology. 305: 331-9. PMID 11124909 DOI: 10.1006/Jmbi.2000.4259  0.674
2001 Ellington AD, Robertson MP. 10 – Ribozyme Selection Rna. 155-186. DOI: 10.1016/B978-008043408-7/50031-9  0.55
2000 Jhaveri S, Rajendran M, Ellington AD. In vitro selection of signaling aptamers. Nature Biotechnology. 18: 1293-7. PMID 11101810 DOI: 10.1038/82414  0.795
2000 Hesselberth J, Robertson MP, Jhaveri S, Ellington AD. In vitro selection of nucleic acids for diagnostic applications. Journal of Biotechnology. 74: 15-25. PMID 10943569 DOI: 10.1016/S1389-0352(99)00005-7  0.808
2000 Marshall KA, Ellington AD. In vitro selection of RNA aptamers. Methods in Enzymology. 318: 193-214. PMID 10889989 DOI: 10.1016/S0076-6879(00)18053-X  0.66
2000 Ellington AD, Khrapov M, Shaw CA. The scene of a frozen accident Rna. 6: 485-498. PMID 10786840 DOI: 10.1017/S1355838200000224  0.381
2000 Robertson MP, Ellington AD. Design and optimization of effector-activated ribozyme ligases. Nucleic Acids Research. 28: 1751-9. PMID 10734194 DOI: 10.1093/Nar/28.8.1751  0.589
2000 Hirao I, Madin K, Endo Y, Yokoyama S, Ellington AD. RNA aptamers that bind to and inhibit the ribosome-inactivating protein, pepocin. Journal of Biological Chemistry. 275: 4943-4948. PMID 10671532 DOI: 10.1074/Jbc.275.7.4943  0.579
2000 Hesselberth JR, Miller D, Robertus J, Ellington AD. In vitro selection of RNA molecules that inhibit the activity of ricin A-chain. The Journal of Biological Chemistry. 275: 4937-42. PMID 10671531 DOI: 10.1074/Jbc.275.7.4937  0.682
2000 Jiang F, Gorin A, Hu W, Majumdar A, Baskerville S, Xu W, Ellington A, Patel DJ. Anchoring an extended HTLV-1 Rex peptide within an RNA major groove containing junctional base triples. Structure (London, England : 1993). 7: 1461-72. PMID 10647177 DOI: 10.1016/S0969-2126(00)88337-9  0.37
2000 Jhaveri SD, Kirby R, Conrad R, Maglott EJ, Bowser M, Kennedy RT, Glick G, Ellington AD. Designed signaling aptamers that transduce molecular recognition to changes in fluorescence intensity Journal of the American Chemical Society. 122: 2469-2473. DOI: 10.1021/Ja992393B  0.79
1999 Marshall KA, Ellington AD. Molecular parasites that evolve longer genomes. Journal of Molecular Evolution. 49: 656-63. PMID 10552046 DOI: 10.1007/Pl00006586  0.623
1999 Marshall KA, Ellington AD. Training ribozymes to switch. Nature Structural Biology. 6: 992-4. PMID 10542083 DOI: 10.1038/14872  0.643
1999 James KD, Ellington AD. The fidelity of template-directed oligonucleotide ligation and the inevitability of polymerase function. Origins of Life and Evolution of Biospheres. 29: 375-390. PMID 10472627 DOI: 10.1023/A:1006544611320  0.342
1999 Matsumura I, Wallingford JB, Surana NK, Vize PD, Ellington AD. Directed evolution of the surface chemistry of the reporter enzyme β- glucuronidase Nature Biotechnology. 17: 696-701. PMID 10404164 DOI: 10.1038/10910  0.687
1999 Ellington AD. Molecular origins and the null hypothesis: Motifs from our maker? The Biological Bulletin. 196: 315-319. PMID 10390829 DOI: 10.2307/1542958  0.38
1999 Baskerville S, Zapp M, Ellington AD. Anti-Rex Aptamers as Mimics of the Rex-Binding Element Journal of Virology. 73: 4962-4971. PMID 10233958 DOI: 10.1128/Jvi.73.6.4962-4971.1999  0.379
1999 Matsumura I, Ellington AD. In vitro evolution of thermostable p53 variants. Protein Science : a Publication of the Protein Society. 8: 731-40. PMID 10211819 DOI: 10.1110/Ps.8.4.731  0.687
1999 Symensma TL, Baskerville S, Yan A, Ellington AD. Polyvalent Rev Decoys Act as Artificial Rev-Responsive Elements Journal of Virology. 73: 4341-4349. PMID 10196332 DOI: 10.1128/Jvi.73.5.4341-4349.1999  0.606
1999 Robertson MP, Ellington AD. In vitro selection of an allosteric ribozyme that transduces analytes to amplicons. Nature Biotechnology. 17: 62-6. PMID 9920271 DOI: 10.1038/5236  0.611
1999 Ellington AD, Hesselberth J, Jhaveri S, Robertson MP. Combinatorial methods: aptamers and aptazymes Proceedings of Spie. 3858: 126-134. DOI: 10.1117/12.372908  0.803
1999 Ye X, Gorin A, Frederick R, Hu W, Majumdar A, Xu W, McLendon G, Ellington A, Patel DJ. RNA architecture dictates the conformations of a bound peptide Chemistry and Biology. 6: 657-669. DOI: 10.1016/S1074-5521(99)80117-3  0.319
1998 Hirao I, Spingola M, Peabody D, Ellington AD. The limits of specificity: an experimental analysis with RNA aptamers to MS2 coat protein variants. Molecular Diversity. 4: 75-89. PMID 10425631 DOI: 10.1023/A:1026401917416  0.568
1998 Jhaveri S, Olwin B, Ellington AD. In vitro selection of phosphorothiolated aptamers Bioorganic and Medicinal Chemistry Letters. 8: 2285-2290. PMID 9873529 DOI: 10.1016/S0960-894X(98)00414-4  0.78
1998 Cox JC, Rudolph P, Ellington AD. Automated RNA selection. Biotechnology Progress. 14: 845-50. PMID 9841645 DOI: 10.1021/Bp980097H  0.364
1998 Rowsell S, Stonehouse NJ, Convery MA, Adams CJ, Ellington AD, Hirao I, Peabody DS, Stockley PG, Phillips SE. Crystal structures of a series of RNA aptamers complexed to the same protein target. Nature Structural Biology. 5: 970-5. PMID 9808042 DOI: 10.1038/2946  0.57
1998 James KD, Boles AR, Henckel D, Ellington AD. The fidelity of template-directed oligonucleotide ligation and its relevance to DNA computation Nucleic Acids Research. 26: 5203-5211. PMID 9801320 DOI: 10.1093/Nar/26.22.5203  0.3
1998 Robertson MP, Ellington AD. Ribozymes. How to make a nucleotide. Nature. 395: 223-5. PMID 9751043 DOI: 10.1038/26117  0.592
1998 Potyrailo RA, Conrad RC, Ellington AD, Hieftje GM. Adapting selected nucleic acid ligands (aptamers) to biosensors. Analytical Chemistry. 70: 3419-25. PMID 9726167 DOI: 10.1021/Ac9802325  0.369
1998 Osborne SE, Matsumura I, Ellington AD. Aptamers as therapeutic and diagnostic reagents: problems and prospects. Current Opinion in Chemical Biology. 1: 5-9. PMID 9667829 DOI: 10.1016/S1367-5931(97)80102-0  0.699
1998 Matsumura I, Ellington AD. DNA shuffling brightens prospects for GFP. Nature Biotechnology. 14: 366. PMID 9630902 DOI: 10.1038/Nbt0396-366  0.682
1998 Bell SD, Denu JM, Dixon JE, Ellington AD. RNA molecules that bind to and inhibit the active site of a tyrosine phosphatase. The Journal of Biological Chemistry. 273: 14309-14. PMID 9603938 DOI: 10.1074/Jbc.273.23.14309  0.371
1998 Convery MA, Rowsell S, Stonehouse NJ, Ellington AD, Hirao I, Murray JB, Peabody DS, Phillips SE, Stockley PG. Crystal structure of an RNA aptamer-protein complex at 2.8 A resolution. Nature Structural Biology. 5: 133-9. PMID 9461079 DOI: 10.1038/Nsb0298-133  0.346
1998 Baskerville S, Frank D, Ellington AD. Directed Evolutionary Descriptions of Natural RNA Structures Cold Spring Harbor Monograph Archive. 35: 203-251. DOI: 10.1101/087969509.35.203  0.363
1998 Bacher JM, Ellington AD. Nucleic acid selection as a tool for drug discovery Drug Discovery Today. 3: 265-273. DOI: 10.1016/S1359-6446(97)01166-5  0.365
1997 Osborne SE, Ellington AD. Nucleic Acid Selection and the Challenge of Combinatorial Chemistry Chemical Reviews. 97: 349-370. PMID 11848874 DOI: 10.1021/Cr960009C  0.331
1997 James KD, Ellington AD. Surprising fidelity of template-directed chemical ligation of oligonucleotides Chemistry & Biology. 4: 595-605. PMID 9281525 DOI: 10.1016/S1074-5521(97)90245-3  0.364
1997 Marshall KA, Robertson MP, Ellington AD. A biopolymer by any other name would bind as well: a comparison of the ligand-binding pockets of nucleic acids and proteins. Structure (London, England : 1993). 5: 729-34. PMID 9261068 DOI: 10.1016/S0969-2126(97)00227-X  0.732
1997 Conrad RC, Symensma TL, Ellington AD. Natural and unnatural answers to evolutionary questions Proceedings of the National Academy of Sciences of the United States of America. 94: 7126-7128. PMID 9207054 DOI: 10.1073/Pnas.94.14.7126  0.348
1997 Robertson MP, Ellington AD. Ribozymes: red in tooth and claw. Current Biology : Cb. 7: R376-9. PMID 9197233 DOI: 10.1016/S0960-9822(06)00179-5  0.582
1997 Ellington AD, Robertson MP, Bull J. Ribozymes in wonderland. Science (New York, N.Y.). 276: 546-7. PMID 9148415 DOI: 10.1126/Science.276.5312.546  0.526
1997 Good PD, Krikos AJ, Li SXL, Bertrand E, Lee NS, Giver L, Ellington A, Zaia JA, Rossi JJ, Engelke DR. Expression of small, therapeutic RNAs in human cell nuclei Gene Therapy. 4: 45-54. PMID 9068795 DOI: 10.1038/Sj.Gt.3300354  0.34
1997 Ye X, Gorin A, Ellington AD, Patel DJ. Deep penetration of an alpha-helix into a widened RNA major groove in the HIV-1 rev peptide-RNA aptamer complex. Nature Structural Biology. 3: 1026-33. PMID 8946856 DOI: 10.1038/Nsb1296-1026  0.353
1996 Lato SM, Ellington AD. Screening chemical libraries for nucleic-acid-binding drugs by in vitro selection: a test case with lividomycin. Molecular Diversity. 2: 103-110. PMID 9238640 DOI: 10.1007/Bf01718707  0.367
1996 Srinivasan J, Leclerc F, Xu W, Ellington AD, Cedergren R. A docking and modelling strategy for peptide–RNA complexes: applications to BIV Tat–TAR and HIV Rev–RBE Folding and Design. 1: 463-472. PMID 9080192 DOI: 10.1016/S1359-0278(96)00062-4  0.323
1996 Ellington AD, Leclerc F, Cedergren R. An RNA groove Nature Structural & Molecular Biology. 3: 981-984. PMID 8946846 DOI: 10.1038/Nsb1296-981  0.313
1996 Conrad R, Ellington AD. Detecting immobilized protein kinase C isozymes with RNA aptamers. Analytical Biochemistry. 242: 261-265. PMID 8937571 DOI: 10.1006/Abio.1996.0462  0.371
1996 Uphoff KW, Bell SD, Ellington AD. In vitro selection of aptamers: the dearth of pure reason. Current Opinion in Structural Biology. 6: 281-288. PMID 8804830 DOI: 10.1016/S0959-440X(96)80045-5  0.363
1996 Xu W, Ellington AD. Anti-peptide aptamers recognize amino acid sequence and bind a protein epitope Proceedings of the National Academy of Sciences of the United States of America. 93: 7475-7480. PMID 8755498 DOI: 10.1073/Pnas.93.15.7475  0.375
1996 Conrad RC, Giver L, Tian Y, Ellington AD. In vitro selection of nucleic acid aptamers that bind proteins Methods in Enzymology. 267: 336-358. PMID 8743326 DOI: 10.1016/S0076-6879(96)67022-0  0.396
1996 Soukup GA, Ellington AD, Maher LJ. Selection of RNAs that bind to duplex DNA at neutral pH Journal of Molecular Biology. 259: 216-228. PMID 8656424 DOI: 10.1006/Jmbi.1996.0314  0.405
1996 Nelson JS, Giver L, Ellington AD, Letsinger RL. Incorporation of a non-nucleotide bridge into hairpin oligonucleotides capable of high-affinity binding to the Rev protein of HIV-1. Biochemistry. 35: 5339-44. PMID 8611522 DOI: 10.1021/Bi952917U  0.321
1996 Symensma TL, Giver L, Zapp M, Takle GB, Ellington AD. RNA aptamers selected to bind human immunodeficiency virus type 1 Rev in vitro are Rev responsive in vivo. Journal of Virology. 70: 179-187. PMID 8523524 DOI: 10.1128/Jvi.70.1.179-187.1996  0.358
1996 Osborne SE, Ellington AD. Incorporating disulfide cross-links at the terminus of oligonucleotides via solid-phase nucleic acid synthesis Bioorganic & Medicinal Chemistry Letters. 6: 2339-2342. DOI: 10.1016/0960-894X(96)00431-3  0.307
1995 Lato SM, Boles AR, Ellington AD. In vitro selection of RNA lectins: using combinatorial chemistry to interpret ribozyme evolution Chemistry & Biology. 2: 291-303. PMID 9383431 DOI: 10.1016/1074-5521(95)90048-9  0.393
1995 Conrad RC, Baskerville S, Ellington AD. In vitro selection methodologies to probe RNA function and structure Molecular Diversity. 1: 69-78. PMID 9237195 DOI: 10.1007/Bf01715810  0.421
1995 Hirao I, Ellington AD. Re-creating the RNA world Current Biology. 5: 1017-1022. PMID 8542277 DOI: 10.1016/S0960-9822(95)00205-3  0.571
1995 Kumar PKR, Ellington A. Artificial evolution and natural ribozymes. The Faseb Journal. 9: 1183-1195. PMID 7672511 DOI: 10.1096/Fasebj.9.12.7672511  0.373
1995 Baskerville S, Ellington AD. RNA Structure: Describing the elephant Current Biology. 5: 120-123. PMID 7538023 DOI: 10.1016/S0960-9822(95)00030-3  0.311
1995 James KD, Ellington AD. The search for missing links between self-replicating nucleic acids and the RNA world. Origins of Life and Evolution of Biospheres. 25: 515-530. PMID 7494634 DOI: 10.1007/Bf01582021  0.312
1994 Leclerc F, Cedergren R, Ellington AD. A three-dimensional model of the Rev-binding element of HIV-1 derived from analyses of aptamers. Nature Structural & Molecular Biology. 1: 293-300. PMID 7664035 DOI: 10.1038/Nsb0594-293  0.355
1994 Ellington AD. RNA Selection: Aptamers achieve the desired recognition Current Biology. 4: 427-429. PMID 7522916 DOI: 10.1016/S0960-9822(00)00093-2  0.388
1994 Giver L, Bartel D, Zapp M, Pawul A, Green M, Ellington AD. Selective optimization of the Rev-binding element of HIV-1. Nucleic Acids Research. 21: 5509-16. PMID 7505429 DOI: 10.1093/Nar/21.23.5509  0.586
1994 Ellington AD. Using in vitro nucleic acid selections for conventional drug design Drug Development Research. 33: 102-115. DOI: 10.1002/Ddr.430330207  0.391
1993 Giver L, Bartel DP, Zapp ML, Green MR, Ellington AD. Selection and design of high-affinity rna ligands for hiv-1 rev Gene. 137: 19-24. PMID 7506689 DOI: 10.1016/0378-1119(93)90246-Y  0.598
1993 Ellington AD. Experimental testing of theories of an early RNA world. Methods in Enzymology. 224: 646-664. PMID 7505384 DOI: 10.1016/0076-6879(93)24048-Y  0.34
1993 Szostak JW, Ellington AD. 20 In Vitro Selection of Functional RNA Sequences Cold Spring Harbor Monograph Archive. 24: 511-533. DOI: 10.1101/087969380.24.511  0.592
1992 Ellington AD, Szostak JW. Selection in vitro of single-stranded DNA molecules that fold into specific ligand-binding structures. Nature. 355: 850-2. PMID 1538766 DOI: 10.1038/355850A0  0.566
1991 Weinhold EG, Glasfeld A, Ellington AD, Benner SA. Structural determinants of stereospecificity in yeast alcohol dehydrogenase. Proceedings of the National Academy of Sciences of the United States of America. 88: 8420-4. PMID 1924300 DOI: 10.1073/Pnas.88.19.8420  0.728
1991 Green R, Ellington AD, Bartel DP, Szostak JW. In vitro genetic analysis: Selection and amplification of rare functional nucleic acids Methods. 2: 75-86. DOI: 10.1016/S1046-2023(05)80127-6  0.746
1990 Michel F, Ellington AD, Couture S, Szostak JW. Phylogenetic and genetic evidence for base-triples in the catalytic domain of group I introns Nature. 347: 578-580. PMID 2215683 DOI: 10.1038/347578A0  0.537
1990 Green R, Ellington AD, Szostak JW. In vitro genetic analysis of the Tetrahymena self-splicing intron. Nature. 347: 406-8. PMID 2215650 DOI: 10.1038/347406A0  0.64
1990 Schultes NP, Ellington AD, Cherry JM, Szostak JW. Saccharomyces cerevisiae homoserine kinase is homologous to prokaryotic homoserine kinases. Gene. 96: 177-80. PMID 2176637 DOI: 10.1016/0378-1119(90)90250-U  0.488
1990 Couture S, Ellington AD, Gerber AS, Cherry JM, Doudna JA, Green R, Hanna M, Pace U, Rajagopal J, Szostak JW. Mutational analysis of conserved nucleotides in a self-splicing group I intron. Journal of Molecular Biology. 215: 345-58. PMID 1700131 DOI: 10.1016/S0022-2836(05)80356-0  0.682
1990 Ellington AD, Szostak JW. In vitro selection of RNA molecules that bind specific ligands Nature. 346: 818-822. PMID 1697402 DOI: 10.1038/346818A0  0.563
1989 Benner S, Ellington AD. Interpreting the behavior of enzymes: purpose or pedigree? Crc Critical Reviews in Biochemistry. 23: 369-426. PMID 3067974 DOI: 10.3109/10409238809082549  0.5
1989 Benner SA, Ellington AD, Tauer A. Modern metabolism as a palimpsest of the RNA world Proceedings of the National Academy of Sciences of the United States of America. 86: 7054-7058. PMID 2476811 DOI: 10.1073/Pnas.86.18.7054  0.499
1988 Benner SA, Ellington AD. Return of the 'last ribo-organism' [7] Nature. 332: 688-689. PMID 2451785 DOI: 10.1038/332688B0  0.429
1987 Ellington AD, Benner SA. Free energy differences between enzyme bound states Journal of Theoretical Biology. 127: 491-506. PMID 3444340 DOI: 10.1016/S0022-5193(87)80145-5  0.462
1987 Benner SA, Allemann RK, Ellington AD, Ge L, Glasfeld A, Leanz GF, Krauch T, MacPherson LJ, Moroney S, Piccirilli JA. Natural selection, protein engineering, and the last riboorganism: rational model building in biochemistry. Cold Spring Harbor Symposia On Quantitative Biology. 52: 53-63. PMID 2456885 DOI: 10.1101/Sqb.1987.052.01.009  0.793
1987 Benner SA, Ellington AD. The last ribo-organism [9] Nature. 329: 295-296. PMID 2442624 DOI: 10.1038/329295A0  0.429
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