| Year |
Citation |
Score |
| 2024 |
Wible DJ, Parikh Z, Cho EJ, Chen MD, Jeter CR, Mukhopadhyay S, Dalby KN, Varadarajan S, Bratton SB. Unexpected inhibition of the lipid kinase PIKfyve reveals an epistatic role for p38 MAPKs in endolysosomal fission and volume control. Cell Death & Disease. 15: 80. PMID 38253602 DOI: 10.1038/s41419-024-06423-0 |
0.6 |
|
| 2023 |
Wible DJ, Parikh Z, Cho EJ, Chen MD, Mukhopadhyay S, Dalby KN, Varadarajan S, Bratton SB. Unexpected inhibition of the lipid kinase PIKfyve reveals an epistatic role for p38 MAPKs in endolysosomal fission and volume control. Biorxiv : the Preprint Server For Biology. PMID 36993747 DOI: 10.1101/2023.03.13.532495 |
0.593 |
|
| 2019 |
Wible DJ, Chao HP, Tang DG, Bratton SB. cancer mutations and alternative mRNA splicing reveal a conjugation switch that regulates ATG12-ATG5-ATG16L1 complex assembly and autophagy. Cell Discovery. 5: 42. PMID 31636955 DOI: 10.1038/S41421-019-0110-1 |
0.301 |
|
| 2018 |
Wible DJ, Bratton SB. Reciprocity in ROS and autophagic signaling. Current Opinion in Toxicology. 7: 28-36. PMID 29457143 DOI: 10.1016/j.cotox.2017.10.006 |
0.334 |
|
| 2017 |
Wu CC, Bratton SB. Caspase-9 swings both ways in the apoptosome. Molecular & Cellular Oncology. 4: e1281865. PMID 28401186 DOI: 10.1080/23723556.2017.1281865 |
0.515 |
|
| 2016 |
Wu CC, Lee S, Malladi S, Chen MD, Mastrandrea NJ, Zhang Z, Bratton SB. The Apaf-1 apoptosome induces formation of caspase-9 homo- and heterodimers with distinct activities. Nature Communications. 7: 13565. PMID 27882936 DOI: 10.1038/Ncomms13565 |
0.695 |
|
| 2015 |
Nowinski SM, Solmonson A, Rundhaug JE, Rho O, Cho J, Lago CU, Riley CL, Lee S, Kohno S, Dao CK, Nikawa T, Bratton SB, Wright CW, Fischer SM, DiGiovanni J, et al. Mitochondrial uncoupling links lipid catabolism to Akt inhibition and resistance to tumorigenesis. Nature Communications. 6: 8137. PMID 26310111 DOI: 10.1038/Ncomms9137 |
0.316 |
|
| 2014 |
Lee S, Challa-Malladi M, Bratton SB, Wright CW. Nuclear factor-κB-inducing kinase (NIK) contains an amino-terminal inhibitor of apoptosis (IAP)-binding motif (IBM) that potentiates NIK degradation by cellular IAP1 (c-IAP1). The Journal of Biological Chemistry. 289: 30680-9. PMID 25246529 DOI: 10.1074/Jbc.M114.587808 |
0.482 |
|
| 2014 |
Mahajan IM, Chen MD, Muro I, Robertson JD, Wright CW, Bratton SB. BH3-only protein BIM mediates heat shock-induced apoptosis. Plos One. 9: e84388. PMID 24427286 DOI: 10.1371/Journal.Pone.0084388 |
0.435 |
|
| 2013 |
Yeh TC, Bratton SB. Caspase-dependent regulation of the ubiquitin-proteasome system through direct substrate targeting. Proceedings of the National Academy of Sciences of the United States of America. 110: 14284-9. PMID 23940367 DOI: 10.1073/pnas.1306179110 |
0.518 |
|
| 2013 |
Wu CC, Bratton SB. Regulation of the intrinsic apoptosis pathway by reactive oxygen species. Antioxidants & Redox Signaling. 19: 546-58. PMID 22978471 DOI: 10.1089/Ars.2012.4905 |
0.466 |
|
| 2011 |
Fisher AA, Labenski MT, Malladi S, Chapman JD, Bratton SB, Monks TJ, Lau SS. The frequency of 1,4-benzoquinone-lysine adducts in cytochrome c correlate with defects in apoptosome activation. Toxicological Sciences : An Official Journal of the Society of Toxicology. 122: 64-72. PMID 21527774 DOI: 10.1093/Toxsci/Kfr085 |
0.603 |
|
| 2011 |
Wu CC, Bratton SB. DARK apoptosome secrets come to light. Structure (London, England : 1993). 19: 4-6. PMID 21220110 DOI: 10.1016/J.Str.2010.12.009 |
0.336 |
|
| 2010 |
Bratton SB, Salvesen GS. Regulation of the Apaf-1-caspase-9 apoptosome. Journal of Cell Science. 123: 3209-14. PMID 20844150 DOI: 10.1242/Jcs.073643 |
0.559 |
|
| 2010 |
Son JK, Varadarajan S, Bratton SB. TRAIL-activated stress kinases suppress apoptosis through transcriptional upregulation of MCL-1. Cell Death and Differentiation. 17: 1288-301. PMID 20168333 DOI: 10.1038/Cdd.2010.9 |
0.724 |
|
| 2010 |
Lau SS, Kuhlman CL, Bratton SB, Monks TJ. Role of hydroquinone-thiol conjugates in benzene-mediated toxicity. Chemico-Biological Interactions. 184: 212-7. PMID 20034486 DOI: 10.1016/J.Cbi.2009.12.016 |
0.322 |
|
| 2009 |
Malladi S, Challa-Malladi M, Fearnhead HO, Bratton SB. The Apaf-1*procaspase-9 apoptosome complex functions as a proteolytic-based molecular timer. The Embo Journal. 28: 1916-25. PMID 19494828 DOI: 10.1038/Emboj.2009.152 |
0.669 |
|
| 2009 |
Choi YE, Butterworth M, Malladi S, Duckett CS, Cohen GM, Bratton SB. The E3 ubiquitin ligase cIAP1 binds and ubiquitinates caspase-3 and -7 via unique mechanisms at distinct steps in their processing. The Journal of Biological Chemistry. 284: 12772-82. PMID 19258326 DOI: 10.1074/Jbc.M807550200 |
0.716 |
|
| 2007 |
Fisher AA, Labenski MT, Malladi S, Gokhale V, Bowen ME, Milleron RS, Bratton SB, Monks TJ, Lau SS. Quinone electrophiles selectively adduct "electrophile binding motifs" within cytochrome c. Biochemistry. 46: 11090-100. PMID 17824617 DOI: 10.1021/Bi700613W |
0.596 |
|
| 2007 |
Challa M, Malladi S, Pellock BJ, Dresnek D, Varadarajan S, Yin YW, White K, Bratton SB. Drosophila Omi, a mitochondrial-localized IAP antagonist and proapoptotic serine protease. The Embo Journal. 26: 3144-56. PMID 17557079 DOI: 10.1038/Sj.Emboj.7601745 |
0.722 |
|
| 2007 |
Fisher AA, Labenski MT, Gokhale V, Bratton S, Monks T, Lau S. Cytochrome c Arylation by 1,4‐Benzoquinone and Its Quinol‐Thioether Metabolites Results in A Loss of Protein Function The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A440 |
0.342 |
|
| 2006 |
Chandra D, Bratton SB, Person MD, Tian Y, Martin AG, Ayres M, Fearnhead HO, Gandhi V, Tang DG. Intracellular nucleotides act as critical prosurvival factors by binding to cytochrome C and inhibiting apoptosome. Cell. 125: 1333-46. PMID 16814719 DOI: 10.1016/J.Cell.2006.05.026 |
0.585 |
|
| 2006 |
Milleron RS, Bratton SB. Heat shock induces apoptosis independently of any known initiator caspase-activating complex. The Journal of Biological Chemistry. 281: 16991-7000. PMID 16618700 DOI: 10.1074/Jbc.M512754200 |
0.587 |
|
| 2006 |
Mufti AR, Burstein E, Csomos RA, Graf PC, Wilkinson JC, Dick RD, Challa M, Son JK, Bratton SB, Su GL, Brewer GJ, Jakob U, Duckett CS. XIAP Is a copper binding protein deregulated in Wilson's disease and other copper toxicosis disorders. Molecular Cell. 21: 775-85. PMID 16543147 DOI: 10.1016/J.Molcel.2006.01.033 |
0.623 |
|
| 2006 |
Chandra D, Ayres M, Gandhi V, Bratton SB, Person MD, Tian Y, Martin AG, Fearnhead HO. Does ATP promote or protect cells from apoptosis? Cancer Biology and Therapy. 5: 712. |
0.407 |
|
| 2004 |
Lewis J, Burstein E, Reffey SB, Bratton SB, Roberts AB, Duckett CS. Uncoupling of the signaling and caspase-inhibitory properties of X-linked inhibitor of apoptosis. The Journal of Biological Chemistry. 279: 9023-9. PMID 14701799 DOI: 10.1074/Jbc.M312891200 |
0.506 |
|
| 2003 |
Bratton SB, Cohen GM. Death receptors leave a caspase footprint that Smacs of XIAP Cell Death and Differentiation. 10: 4-6. PMID 12655287 DOI: 10.1038/Sj.Cdd.4401176 |
0.447 |
|
| 2002 |
Bratton SB, Lewis J, Butterworth M, Duckett CS, Cohen GM. XIAP inhibition of caspase-3 preserves its association with the Apaf-1 apoptosome and prevents CD95- and Bax-induced apoptosis Cell Death and Differentiation. 9: 881-892. PMID 12181739 DOI: 10.1038/Sj.Cdd.4401069 |
0.62 |
|
| 2002 |
MacFarlane M, Merrison W, Bratton SB, Cohen GM. Proteasome-mediated degradation of Smac during apoptosis: XIAP promotes Smac ubiquitination in vitro. The Journal of Biological Chemistry. 277: 36611-6. PMID 12121969 DOI: 10.1074/Jbc.M200317200 |
0.629 |
|
| 2002 |
Cain K, Bratton SB, Cohen GM. The Apaf-1 apoptosome: a large caspase-activating complex. Biochimie. 84: 203-14. PMID 12022951 DOI: 10.1016/S0300-9084(02)01376-7 |
0.595 |
|
| 2002 |
Sun XM, Bratton SB, Butterworth M, MacFarlane M, Cohen GM. Bcl-2 and Bcl-xL inhibit CD95-mediated apoptosis by preventing mitochondrial release of Smac/DIABLO and subsequent inactivation of X-linked inhibitor-of-apoptosis protein. The Journal of Biological Chemistry. 277: 11345-51. PMID 11801595 DOI: 10.1074/Jbc.M109893200 |
0.596 |
|
| 2001 |
Bratton SB, Cohen GM. Caspase cascades in chemically-induced apoptosis Advances in Experimental Medicine and Biology. 500: 407-420. PMID 11764974 DOI: 10.1007/978-1-4615-0667-6_63 |
0.618 |
|
| 2001 |
Bratton SB, Walker G, Roberts DL, Cain K, Cohen GM. Caspase-3 cleaves Apaf-1 into an ∼ 30 kDa fragment that associates with an inappropriately oligomerized and biologically inactive ∼ 1.4 MDa apoptosome complex Cell Death and Differentiation. 8: 425-433. PMID 11550094 DOI: 10.1038/Sj.Cdd.4400834 |
0.575 |
|
| 2001 |
Bratton SB, Cohen GM. Apoptotic death sensor: An organelle's alter ego? Trends in Pharmacological Sciences. 22: 306-315. PMID 11395159 DOI: 10.1016/S0165-6147(00)01718-1 |
0.632 |
|
| 2001 |
Bratton SB, Walker G, Srinivasula SM, Sun XM, Butterworth M, Alnemri ES, Cohen GM. Recruitment, activation and retention of caspases-9 and-3 by Apaf-1 apoptosome and associated XIAP complexes Embo Journal. 20: 998-1009. PMID 11230124 DOI: 10.1093/Emboj/20.5.998 |
0.628 |
|
| 2000 |
Bratton SB, Lau SS, Monks TJ. The putative benzene metabolite 2,3,5-tris(glutathion-S-yl)hydroquinone depletes glutathione, stimulates sphingomyelin turnover, and induces apoptosis in HL-60 cells Chemical Research in Toxicology. 13: 550-556. PMID 10898586 DOI: 10.1021/Tx0000015 |
0.595 |
|
| 2000 |
Bratton SB, MacFarlane M, Cain K, Cohen GM. Protein complexes activate distinct caspase cascades in death receptor and stress-induced apoptosis Experimental Cell Research. 256: 27-33. PMID 10739648 DOI: 10.1006/Excr.2000.4835 |
0.61 |
|
| 2000 |
Cain K, Bratton SB, Langlais C, Walker G, Brown DG, Sun XM, Cohen GM. Apaf-1 oligomerizes into biologically active ~700-kDa and inactive ~1.4-MDa apoptosome complexes Journal of Biological Chemistry. 275: 6067-6070. PMID 10692394 DOI: 10.1074/Jbc.275.9.6067 |
0.523 |
|
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