Didier Trono - Publications

Affiliations: 
School of Life Sciences École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland 

165 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Wolf G, de Iaco A, Sun MA, Bruno M, Tinkham M, Hoang D, Mitra A, Ralls S, Trono D, Macfarlan TS. KRAB-zinc finger protein gene expansion in response to active retrotransposons in the murine lineage. Elife. 9. PMID 32479262 DOI: 10.7554/eLife.56337  0.32
2016 Ecco G, Cassano M, Kauzlaric A, Duc J, Coluccio A, Offner S, Imbeault M, Rowe HM, Turelli P, Trono D. Transposable Elements and Their KRAB-ZFP Controllers Regulate Gene Expression in Adult Tissues. Developmental Cell. 36: 611-23. PMID 27003935 DOI: 10.1016/j.devcel.2016.02.024  0.44
2016 Ecco G, Rowe HM, Trono D. A Large-Scale Functional Screen to Identify Epigenetic Repressors of Retrotransposon Expression. Methods in Molecular Biology (Clifton, N.J.). 1400: 403-17. PMID 26895067 DOI: 10.1007/978-1-4939-3372-3_25  0.32
2015 Kapopoulou A, Mathew L, Wong A, Trono D, Jensen JD. The evolution of gene expression and binding specificity of the largest transcription factor family in primates. Evolution; International Journal of Organic Evolution. PMID 26593440 DOI: 10.1111/evo.12819  0.32
2015 Friedli M, Trono D. The Developmental Control of Transposable Elements and the Evolution of Higher Species. Annual Review of Cell and Developmental Biology. 31: 429-51. PMID 26393776 DOI: 10.1146/annurev-cellbio-100814-125514  0.44
2015 Dietrich JE, Panavaite L, Gunther S, Wennekamp S, Groner AC, Pigge A, Salvenmoser S, Trono D, Hufnagel L, Hiiragi T. Venus trap in the mouse embryo reveals distinct molecular dynamics underlying specification of first embryonic lineages. Embo Reports. 16: 1005-21. PMID 26142281 DOI: 10.15252/embr.201540162  0.44
2015 Rauwel B, Jang SM, Cassano M, Kapopoulou A, Barde I, Trono D. Release of human cytomegalovirus from latency by a KAP1/TRIM28 phosphorylation switch. Elife. 4. PMID 25846574 DOI: 10.7554/eLife.06068  0.44
2015 Singh K, Cassano M, Planet E, Sebastian S, Jang SM, Sohi G, Faralli H, Choi J, Youn HD, Dilworth FJ, Trono D. A KAP1 phosphorylation switch controls MyoD function during skeletal muscle differentiation. Genes & Development. 29: 513-25. PMID 25737281 DOI: 10.1101/gad.254532.114  0.44
2015 Fasching L, Kapopoulou A, Sachdeva R, Petri R, Jönsson ME, Männe C, Turelli P, Jern P, Cammas F, Trono D, Jakobsson J. TRIM28 represses transcription of endogenous retroviruses in neural progenitor cells. Cell Reports. 10: 20-8. PMID 25543143 DOI: 10.1016/j.celrep.2014.12.004  0.44
2014 Gubelmann C, Schwalie PC, Raghav SK, Röder E, Delessa T, Kiehlmann E, Waszak SM, Corsinotti A, Udin G, Holcombe W, Rudofsky G, Trono D, Wolfrum C, Deplancke B. Identification of the transcription factor ZEB1 as a central component of the adipogenic gene regulatory network. Elife. 3: e03346. PMID 25163748 DOI: 10.7554/eLife.03346  0.44
2014 Castro-Diaz N, Ecco G, Coluccio A, Kapopoulou A, Yazdanpanah B, Friedli M, Duc J, Jang SM, Turelli P, Trono D. Evolutionally dynamic L1 regulation in embryonic stem cells. Genes & Development. 28: 1397-409. PMID 24939876 DOI: 10.1101/gad.241661.114  0.32
2014 Turelli P, Castro-Diaz N, Marzetta F, Kapopoulou A, Raclot C, Duc J, Tieng V, Quenneville S, Trono D. Interplay of TRIM28 and DNA methylation in controlling human endogenous retroelements. Genome Research. 24: 1260-70. PMID 24879559 DOI: 10.1101/gr.172833.114  0.32
2014 Friedli M, Turelli P, Kapopoulou A, Rauwel B, Castro-Díaz N, Rowe HM, Ecco G, Unzu C, Planet E, Lombardo A, Mangeat B, Wildhaber BE, Naldini L, Trono D. Loss of transcriptional control over endogenous retroelements during reprogramming to pluripotency. Genome Research. 24: 1251-9. PMID 24879558 DOI: 10.1101/gr.172809.114  0.32
2014 Chiriaco M, Farinelli G, Capo V, Zonari E, Scaramuzza S, Di Matteo G, Sergi LS, Migliavacca M, Hernandez RJ, Bombelli F, Giorda E, Kajaste-Rudnitski A, Trono D, Grez M, Rossi P, et al. Dual-regulated lentiviral vector for gene therapy of X-linked chronic granulomatosis. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1472-83. PMID 24869932 DOI: 10.1038/mt.2014.87  0.32
2014 Barde I, Rauwel B, Marin-Florez RM, Corsinotti A, Laurenti E, Verp S, Offner S, Marquis J, Kapopoulou A, Vanicek J, Trono D. [A KRAB/KAP1-miRNA cascade regulates erythropoiesis through stage-specific control of mitophagy]. MéDecine Sciences : M/S. 30: 12-5. PMID 24472449 DOI: 10.1051/medsci/20143001003  0.32
2013 Jaguva Vasudevan AA, Perkovic M, Bulliard Y, Cichutek K, Trono D, Häussinger D, Münk C. Prototype foamy virus Bet impairs the dimerization and cytosolic solubility of human APOBEC3G. Journal of Virology. 87: 9030-40. PMID 23760237 DOI: 10.1128/JVI.03385-12  0.32
2013 Andrey G, Montavon T, Mascrez B, Gonzalez F, Noordermeer D, Leleu M, Trono D, Spitz F, Duboule D. A switch between topological domains underlies HoxD genes collinearity in mouse limbs. Science (New York, N.Y.). 340: 1234167. PMID 23744951 DOI: 10.1126/science.1234167  0.32
2013 Barde I, Rauwel B, Marin-Florez RM, Corsinotti A, Laurenti E, Verp S, Offner S, Marquis J, Kapopoulou A, Vanicek J, Trono D. A KRAB/KAP1-miRNA cascade regulates erythropoiesis through stage-specific control of mitophagy. Science (New York, N.Y.). 340: 350-3. PMID 23493425 DOI: 10.1126/science.1232398  0.32
2013 Corsinotti A, Kapopoulou A, Gubelmann C, Imbeault M, Santoni de Sio FR, Rowe HM, Mouscaz Y, Deplancke B, Trono D. Global and stage specific patterns of Krüppel-associated-box zinc finger protein gene expression in murine early embryonic cells. Plos One. 8: e56721. PMID 23451074 DOI: 10.1371/journal.pone.0056721  0.32
2013 Márquez C, Poirier GL, Cordero MI, Larsen MH, Groner A, Marquis J, Magistretti PJ, Trono D, Sandi C. Peripuberty stress leads to abnormal aggression, altered amygdala and orbitofrontal reactivity and increased prefrontal MAOA gene expression. Translational Psychiatry. 3: e216. PMID 23321813 DOI: 10.1038/tp.2012.144  0.32
2013 Rowe HM, Friedli M, Offner S, Verp S, Mesnard D, Marquis J, Aktas T, Trono D. De novo DNA methylation of endogenous retroviruses is shaped by KRAB-ZFPs/KAP1 and ESET. Development (Cambridge, England). 140: 519-29. PMID 23293284 DOI: 10.1242/dev.087585  0.32
2013 Rowe HM, Kapopoulou A, Corsinotti A, Fasching L, Macfarlan TS, Tarabay Y, Viville S, Jakobsson J, Pfaff SL, Trono D. TRIM28 repression of retrotransposon-based enhancers is necessary to preserve transcriptional dynamics in embryonic stem cells. Genome Research. 23: 452-61. PMID 23233547 DOI: 10.1101/gr.147678.112  0.32
2012 Quenneville S, Turelli P, Bojkowska K, Raclot C, Offner S, Kapopoulou A, Trono D. The KRAB-ZFP/KAP1 system contributes to the early embryonic establishment of site-specific DNA methylation patterns maintained during development. Cell Reports. 2: 766-73. PMID 23041315 DOI: 10.1016/j.celrep.2012.08.043  0.32
2012 Santoni de Sio FR, Barde I, Offner S, Kapopoulou A, Corsinotti A, Bojkowska K, Genolet R, Thomas JH, Luescher IF, Pinschewer D, Harris N, Trono D. KAP1 regulates gene networks controlling T-cell development and responsiveness. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 4561-75. PMID 22872677 DOI: 10.1096/fj.12-206177  0.32
2012 Åkerblom M, Sachdeva R, Barde I, Verp S, Gentner B, Trono D, Jakobsson J. MicroRNA-124 is a subventricular zone neuronal fate determinant. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 8879-89. PMID 22745489 DOI: 10.1523/JNEUROSCI.0558-12.2012  0.32
2012 Macfarlan TS, Gifford WD, Driscoll S, Lettieri K, Rowe HM, Bonanomi D, Firth A, Singer O, Trono D, Pfaff SL. Embryonic stem cell potency fluctuates with endogenous retrovirus activity. Nature. 487: 57-63. PMID 22722858 DOI: 10.1038/nature11244  0.32
2012 Bojkowska K, Aloisio F, Cassano M, Kapopoulou A, Santoni de Sio F, Zangger N, Offner S, Cartoni C, Thomas C, Quenneville S, Johnsson K, Trono D. Liver-specific ablation of Krüppel-associated box-associated protein 1 in mice leads to male-predominant hepatosteatosis and development of liver adenoma. Hepatology (Baltimore, Md.). 56: 1279-90. PMID 22684873 DOI: 10.1002/hep.25767  0.32
2012 Groner AC, Tschopp P, Challet L, Dietrich JE, Verp S, Offner S, Barde I, Rodriguez I, Hiiragi T, Trono D. The Krüppel-associated box repressor domain can induce reversible heterochromatization of a mouse locus in vivo. The Journal of Biological Chemistry. 287: 25361-9. PMID 22605343 DOI: 10.1074/jbc.M112.350884  0.32
2012 Trono D. Gene therapy: too much splice can spoil the dish. The Journal of Clinical Investigation. 122: 1600-2. PMID 22523063 DOI: 10.1172/JCI63066  0.32
2012 Santoni de Sio FR, Massacand J, Barde I, Offner S, Corsinotti A, Kapopoulou A, Bojkowska K, Dagklis A, Fernandez M, Ghia P, Thomas JH, Pinschewer D, Harris N, Trono D. KAP1 regulates gene networks controlling mouse B-lymphoid cell differentiation and function. Blood. 119: 4675-85. PMID 22452978 DOI: 10.1182/blood-2011-12-401117  0.32
2012 White D, Rafalska-Metcalf IU, Ivanov AV, Corsinotti A, Peng H, Lee SC, Trono D, Janicki SM, Rauscher FJ. The ATM substrate KAP1 controls DNA repair in heterochromatin: regulation by HP1 proteins and serine 473/824 phosphorylation. Molecular Cancer Research : McR. 10: 401-14. PMID 22205726 DOI: 10.1158/1541-7786.MCR-11-0134  0.32
2011 Quenneville S, Verde G, Corsinotti A, Kapopoulou A, Jakobsson J, Offner S, Baglivo I, Pedone PV, Grimaldi G, Riccio A, Trono D. In embryonic stem cells, ZFP57/KAP1 recognize a methylated hexanucleotide to affect chromatin and DNA methylation of imprinting control regions. Molecular Cell. 44: 361-72. PMID 22055183 DOI: 10.1016/j.molcel.2011.08.032  0.32
2011 Meylan S, Groner AC, Ambrosini G, Malani N, Quenneville S, Zangger N, Kapopoulou A, Kauzlaric A, Rougemont J, Ciuffi A, Bushman FD, Bucher P, Trono D. A gene-rich, transcriptionally active environment and the pre-deposition of repressive marks are predictive of susceptibility to KRAB/KAP1-mediated silencing. Bmc Genomics. 12: 378. PMID 21791101 DOI: 10.1186/1471-2164-12-378  0.32
2011 Bojkowska K, Santoni de Sio F, Barde I, Offner S, Verp S, Heinis C, Johnsson K, Trono D. Measuring in vivo protein half-life. Chemistry & Biology. 18: 805-15. PMID 21700215 DOI: 10.1016/j.chembiol.2011.03.014  0.32
2011 Barde I, Laurenti E, Verp S, Wiznerowicz M, Offner S, Viornery A, Galy A, Trumpp A, Trono D. Lineage-and stage-restricted lentiviral vectors for the gene therapy of chronic granulomatous disease Gene Therapy. 18: 1087-1097. PMID 21544095 DOI: 10.1038/gt.2011.65  0.32
2011 Robyr D, Friedli M, Gehrig C, Arcangeli M, Marin M, Guipponi M, Farinelli L, Barde I, Verp S, Trono D, Antonarakis SE. Chromosome conformation capture uncovers potential genome-wide interactions between human conserved non-coding sequences. Plos One. 6: e17634. PMID 21408183 DOI: 10.1371/journal.pone.0017634  0.32
2011 Trono D, Marzetta F. Profaning the ultimate sanctuary: HIV latency in hematopoietic stem cells. Cell Host & Microbe. 9: 170-2. PMID 21402354 DOI: 10.1016/j.chom.2011.03.001  0.32
2011 Pasi CE, Dereli-Öz A, Negrini S, Friedli M, Fragola G, Lombardo A, Van Houwe G, Naldini L, Casola S, Testa G, Trono D, Pelicci PG, Halazonetis TD. Genomic instability in induced stem cells. Cell Death and Differentiation. 18: 745-53. PMID 21311564 DOI: 10.1038/cdd.2011.9  0.32
2011 Rowe HM, Trono D. Dynamic control of endogenous retroviruses during development. Virology. 411: 273-87. PMID 21251689 DOI: 10.1016/j.virol.2010.12.007  0.32
2011 Maillard PV, Zoete V, Michielin O, Trono D. Homology-based identification of capsid determinants that protect HIV1 from human TRIM5α restriction. The Journal of Biological Chemistry. 286: 8128-40. PMID 21169362 DOI: 10.1074/jbc.M110.187609  0.32
2011 Bulliard Y, Narvaiza I, Bertero A, Peddi S, Röhrig UF, Ortiz M, Zoete V, Castro-Díaz N, Turelli P, Telenti A, Michielin O, Weitzman MD, Trono D. Structure-function analyses point to a polynucleotide-accommodating groove essential for APOBEC3A restriction activities. Journal of Virology. 85: 1765-76. PMID 21123384 DOI: 10.1128/JVI.01651-10  0.32
2010 Friedli M, Barde I, Arcangeli M, Verp S, Quazzola A, Zakany J, Lin-Marq N, Robyr D, Attanasio C, Spitz F, Duboule D, Trono D, Antonarakis SE. A systematic enhancer screen using lentivector transgenesis identifies conserved and non-conserved functional elements at the Olig1 and Olig2 locus. Plos One. 5: e15741. PMID 21206754 DOI: 10.1371/journal.pone.0015741  0.32
2010 Barde I, Salmon P, Trono D. Production and titration of lentiviral vectors. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 4.21. PMID 20938923 DOI: 10.1002/0471142301.ns0421s53  0.32
2010 Laurenti E, Barde I, Verp S, Offner S, Wilson A, Quenneville S, Wiznerowicz M, Macdonald HR, Trono D, Trumpp A. Inducible gene and shRNA expression in resident hematopoietic stem cells in vivo. Stem Cells (Dayton, Ohio). 28: 1390-8. PMID 20641037 DOI: 10.1002/stem.460  0.32
2010 Trono D, Van Lint C, Rouzioux C, Verdin E, Barré-Sinoussi F, Chun TW, Chomont N. HIV persistence and the prospect of long-term drug-free remissions for hiv-infected individuals Science. 329: 174-180. PMID 20616270 DOI: 10.1126/science.1191047  0.32
2010 Busskamp V, Duebel J, Balya D, Fradot M, Viney TJ, Siegert S, Groner AC, Cabuy E, Forster V, Seeliger M, Biel M, Humphries P, Paques M, Mohand-Said S, Trono D, et al. Genetic reactivation of cone photoreceptors restores visual responses in retinitis pigmentosa. Science (New York, N.Y.). 329: 413-7. PMID 20576849 DOI: 10.1126/science.1190897  0.32
2010 Groner AC, Meylan S, Ciuffi A, Zangger N, Ambrosini G, Dénervaud N, Bucher P, Trono D. KRAB-zinc finger proteins and KAP1 can mediate long-range transcriptional repression through heterochromatin spreading. Plos Genetics. 6: e1000869. PMID 20221260 DOI: 10.1371/journal.pgen.1000869  0.32
2010 Maillard PV, Ecco G, Ortiz M, Trono D. The specificity of TRIM5 alpha-mediated restriction is influenced by its coiled-coil domain. Journal of Virology. 84: 5790-801. PMID 20219908 DOI: 10.1128/JVI.02413-09  0.32
2010 Rowe HM, Jakobsson J, Mesnard D, Rougemont J, Reynard S, Aktas T, Maillard PV, Layard-Liesching H, Verp S, Marquis J, Spitz F, Constam DB, Trono D. KAP1 controls endogenous retroviruses in embryonic stem cells. Nature. 463: 237-40. PMID 20075919 DOI: 10.1038/nature08674  0.32
2009 Meylan S, Trono D. Innate immunity against retroviral pathogens: from an ambiguous genetic self to novel therapeutic approaches. Swiss Medical Weekly. 139: 706-11. PMID 20047133  0.32
2009 Bulliard Y, Turelli P, Röhrig UF, Zoete V, Mangeat B, Michielin O, Trono D. Functional analysis and structural modeling of human APOBEC3G reveal the role of evolutionarily conserved elements in the inhibition of human immunodeficiency virus type 1 infection and Alu transposition. Journal of Virology. 83: 12611-21. PMID 19776130 DOI: 10.1128/JVI.01491-09  0.32
2009 Barde I, Laurenti E, Verp S, Groner AC, Towne C, Padrun V, Aebischer P, Trumpp A, Trono D. Regulation of episomal gene expression by KRAB/KAP1-mediated histone modifications. Journal of Virology. 83: 5574-80. PMID 19279087 DOI: 10.1128/JVI.00001-09  0.44
2009 Meyer K, Marquis J, Trüb J, Nlend Nlend R, Verp S, Ruepp MD, Imboden H, Barde I, Trono D, Schümperli D. Rescue of a severe mouse model for spinal muscular atrophy by U7 snRNA-mediated splicing modulation. Human Molecular Genetics. 18: 546-55. PMID 19010792 DOI: 10.1093/hmg/ddn382  0.44
2008 Jakobsson J, Cordero MI, Bisaz R, Groner AC, Busskamp V, Bensadoun JC, Cammas F, Losson R, Mansuy IM, Sandi C, Trono D. KAP1-mediated epigenetic repression in the forebrain modulates behavioral vulnerability to stress. Neuron. 60: 818-31. PMID 19081377 DOI: 10.1016/j.neuron.2008.09.036  0.44
2008 Malashicheva AB, Kanzler B, Tolkunova EN, Trono D, Tomilin AN. The application of lentiviral vectors for tissue-specific gene manipulations Tsitologiya. 50: 370-375. PMID 18664120  0.44
2008 Asparuhova MB, Barde I, Trono D, Schranz K, Schümperli D. Development and characterization of a triple combination gene therapy vector inhibiting HIV-1 multiplication. The Journal of Gene Medicine. 10: 1059-70. PMID 18642399 DOI: 10.1002/jgm.1238  0.44
2008 Bach D, Peddi S, Mangeat B, Lakkaraju A, Strub K, Trono D. Characterization of APOBEC3G binding to 7SL RNA. Retrovirology. 5: 54. PMID 18597676 DOI: 10.1186/1742-4690-5-54  0.44
2008 Diaz-Griffero F, Perron M, McGee-Estrada K, Hanna R, Maillard PV, Trono D, Sodroski J. A human TRIM5alpha B30.2/SPRY domain mutant gains the ability to restrict and prematurely uncoat B-tropic murine leukemia virus. Virology. 378: 233-42. PMID 18586294 DOI: 10.1016/j.virol.2008.05.008  0.44
2008 Sauvain MO, Dorr AP, Stevenson B, Quazzola A, Naef F, Wiznerowicz M, Schütz F, Jongeneel V, Duboule D, Spitz F, Trono D. Genotypic features of lentivirus transgenic mice. Journal of Virology. 82: 7111-9. PMID 18463153 DOI: 10.1128/JVI.00623-08  0.44
2008 Turelli P, Liagre-Quazzola A, Mangeat B, Verp S, Jost S, Trono D. APOBEC3-independent interferon-induced viral clearance in hepatitis B virus transgenic mice. Journal of Virology. 82: 6585-90. PMID 18434399 DOI: 10.1128/JVI.00216-08  0.44
2008 Genoud N, Ott D, Braun N, Prinz M, Schwarz P, Suter U, Trono D, Aguzzi A. Antiprion prophylaxis by gene transfer of a soluble prion antagonist. The American Journal of Pathology. 172: 1287-96. PMID 18372425 DOI: 10.2353/ajpath.2008.070836  0.44
2007 Salmon P, Trono D. Production and titration of lentiviral vectors. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. Unit 12.10. PMID 18428406 DOI: 10.1002/0471142905.hg1210s54  0.44
2007 Maillard PV, Reynard S, Serhan F, Turelli P, Trono D. Interfering residues narrow the spectrum of MLV restriction by human TRIM5alpha. Plos Pathogens. 3: e200. PMID 18166079 DOI: 10.1371/journal.ppat.0030200  0.32
2007 Wiznerowicz M, Jakobsson J, Szulc J, Liao S, Quazzola A, Beermann F, Aebischer P, Trono D. The Kruppel-associated box repressor domain can trigger de novo promoter methylation during mouse early embryogenesis. The Journal of Biological Chemistry. 282: 34535-41. PMID 17893143 DOI: 10.1074/jbc.M705898200  0.32
2007 Dayer AG, Jenny B, Sauvain MO, Potter G, Salmon P, Zgraggen E, Kanemitsu M, Gascon E, Sizonenko S, Trono D, Kiss JZ. Expression of FGF-2 in neural progenitor cells enhances their potential for cellular brain repair in the rodent cortex. Brain : a Journal of Neurology. 130: 2962-76. PMID 17728358 DOI: 10.1093/brain/awm200  0.44
2007 Jost S, Turelli P, Mangeat B, Protzer U, Trono D. Induction of antiviral cytidine deaminases does not explain the inhibition of hepatitis B virus replication by interferons. Journal of Virology. 81: 10588-96. PMID 17652382 DOI: 10.1128/JVI.02489-06  0.44
2007 Malashicheva A, Kanzler B, Tolkunova E, Trono D, Tomilin A. Lentivirus as a tool for lineage-specific gene manipulations. Genesis (New York, N.Y. : 2000). 45: 456-9. PMID 17607693 DOI: 10.1002/dvg.20313  0.44
2007 Asparuhova MB, Marti G, Liu S, Serhan F, Trono D, Schümperli D. Inhibition of HIV-1 multiplication by a modified U7 snRNA inducing Tat and Rev exon skipping. The Journal of Gene Medicine. 9: 323-34. PMID 17474072 DOI: 10.1002/jgm.1027  0.44
2007 Zhang KL, Mangeat B, Ortiz M, Zoete V, Trono D, Telenti A, Michielin O. Model structure of human APOBEC3G. Plos One. 2: e378. PMID 17440614 DOI: 10.1371/journal.pone.0000378  0.44
2007 Trono D. [Didier Trono, dean of life sciences at the EPFL: "we want to give a twist to biomedical research"]. Revue MéDicale Suisse. 3: 3-6. PMID 17354652  0.44
2007 Rideau A, Mangeat B, Matthes T, Trono D, Beris P. Molecular mechanism of hepcidin deficiency in a patient with juvenile hemochromatosis. Haematologica. 92: 127-8. PMID 17229647 DOI: 10.3324/haematol.10545  0.44
2007 Fodor A, Harel C, Fodor L, Armoni M, Salmon P, Trono D, Karnieli E. Adult rat liver cells transdifferentiated with lentiviral IPF1 vectors reverse diabetes in mice: An ex vivo gene therapy approach Diabetologia. 50: 121-130. PMID 17131142 DOI: 10.1007/s00125-006-0509-8  0.44
2007 Malashicheva A, Kanzler B, Tolkunova E, Trono D, Tomilin A. Lentivirus as a tool for lineage-specific gene manipulations (Genesis 45, 7, (456-459)) Genesis. 45: 793. DOI: 10.1002/dvg.20368  0.44
2006 Salmon P, Trono D. Production and titration of lentiviral vectors. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 4.21. PMID 18428637 DOI: 10.1002/0471142301.ns0421s37  0.44
2006 Nguyen TH, Birraux J, Wildhaber B, Myara A, Trivin F, Le Coultre C, Trono D, Chardot C. Ex vivo lentivirus transduction and immediate transplantation of uncultured hepatocytes for treating hyperbilirubinemic Gunn rat. Transplantation. 82: 794-803. PMID 17006327 DOI: 10.1097/01.tp.0000234675.56598.35  0.44
2006 Wiznerowicz M, Szulc J, Trono D. Tuning silence: conditional systems for RNA interference. Nature Methods. 3: 682-8. PMID 16929312 DOI: 10.1038/nmeth914  0.44
2006 Ariumi Y, Serhan F, Turelli P, Telenti A, Trono D. The integrase interactor 1 (INI1) proteins facilitate Tat-mediated human immunodeficiency virus type 1 transcription. Retrovirology. 3: 47. PMID 16889668 DOI: 10.1186/1742-4690-3-47  0.44
2006 Eberhardt M, Salmon P, von Mach MA, Hengstler JG, Brulport M, Linscheid P, Seboek D, Oberholzer J, Barbero A, Martin I, Müller B, Trono D, Zulewski H. Multipotential nestin and Isl-1 positive mesenchymal stem cells isolated from human pancreatic islets. Biochemical and Biophysical Research Communications. 345: 1167-76. PMID 16713999 DOI: 10.1016/j.bbrc.2006.05.016  0.44
2006 Nadra K, Anghel SI, Joye E, Tan NS, Basu-Modak S, Trono D, Wahli W, Desvergne B. Differentiation of trophoblast giant cells and their metabolic functions are dependent on peroxisome proliferator-activated receptor beta/delta. Molecular and Cellular Biology. 26: 3266-81. PMID 16581799 DOI: 10.1128/MCB.26.8.3266-3281.2006  0.44
2006 Ariumi Y, Trono D. Ataxia-telangiectasia-mutated (ATM) protein can enhance human immunodeficiency virus type 1 replication by stimulating Rev function. Journal of Virology. 80: 2445-52. PMID 16474151 DOI: 10.1128/JVI.80.5.2445-2452.2006  0.44
2006 Szulc J, Wiznerowicz M, Sauvain MO, Trono D, Aebischer P. A versatile tool for conditional gene expression and knockdown. Nature Methods. 3: 109-16. PMID 16432520 DOI: 10.1038/nmeth846  0.44
2006 Salmon P, Trono D. Design and Production of Human Immunodeficiency Virus-Derived Vectors Cell Biology, Four-Volume Set. 1: 425-434. DOI: 10.1016/B978-012164730-8/50053-8  0.44
2005 Nguyen TH, Khakhoulina T, Simmons A, Morel P, Trono D. A simple and highly effective method for the stable transduction of uncultured porcine hepatocytes using lentiviral vector. Cell Transplantation. 14: 489-96. PMID 16285257  0.44
2005 Mai G, Nguyen TH, Huy NT, Morel P, Mei J, Andres A, Bosco D, Baertschiger R, Toso C, Berney T, Majno P, Mentha G, Trono D, Buhler LH. Treatment of fulminant liver failure by transplantation of microencapsulated primary or immortalized xenogeneic hepatocytes. Xenotransplantation. 12: 457-64. PMID 16202069 DOI: 10.1111/j.1399-3089.2005.00248.x  0.44
2005 Nguyen TH, Mai G, Villiger P, Oberholzer J, Salmon P, Morel P, Bühler L, Trono D. Treatment of acetaminophen-induced acute liver failure in the mouse with conditionally immortalized human hepatocytes. Journal of Hepatology. 43: 1031-7. PMID 16169114 DOI: 10.1016/j.jhep.2005.05.036  0.44
2005 Nguyen TH, Bellodi-Privato M, Aubert D, Pichard V, Myara A, Trono D, Ferry N. Therapeutic lentivirus-mediated neonatal in vivo gene therapy in hyperbilirubinemic Gunn rats. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 852-9. PMID 16140582 DOI: 10.1016/j.ymthe.2005.06.482  0.44
2005 Themis M, Waddington SN, Schmidt M, von Kalle C, Wang Y, Al-Allaf F, Gregory LG, Nivsarkar M, Themis M, Holder MV, Buckley SM, Dighe N, Ruthe AT, Mistry A, Bigger B, ... ... Trono D, et al. Oncogenesis following delivery of a nonprimate lentiviral gene therapy vector to fetal and neonatal mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 763-71. PMID 16084128 DOI: 10.1016/j.ymthe.2005.07.358  0.44
2005 Verhoeyen E, Wiznerowicz M, Olivier D, Izac B, Trono D, Dubart-Kupperschmitt A, Cosset FL. Novel lentiviral vectors displaying "early-acting cytokines" selectively promote survival and transduction of NOD/SCID repopulating human hematopoietic stem cells. Blood. 106: 3386-95. PMID 16076865 DOI: 10.1182/blood-2004-12-4736  0.44
2005 Mangeat B, Trono D. Lentiviral vectors and antiretroviral intrinsic immunity. Human Gene Therapy. 16: 913-20. PMID 16076249 DOI: 10.1089/hum.2005.16.913  0.44
2005 Kvell K, Nguyen TH, Salmon P, Glauser F, Werner-Favre C, Barnet M, Schneider P, Trono D, Zubler RH. Transduction of CpG DNA-stimulated primary human B cells with bicistronic lentivectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 892-9. PMID 16005685 DOI: 10.1016/j.ymthe.2005.05.010  0.44
2005 Arnaud C, Burger F, Steffens S, Veillard NR, Nguyen TH, Trono D, Mach F. Statins reduce interleukin-6-induced C-reactive protein in human hepatocytes: new evidence for direct antiinflammatory effects of statins. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 1231-6. PMID 15790934 DOI: 10.1161/01.ATV.0000163840.63685.0c  0.44
2005 Miyake K, Flygare J, Kiefer T, Utsugisawa T, Richter J, Ma Z, Wiznerowicz M, Trono D, Karlsson S. Development of cellular models for ribosomal protein S19 (RPS19)-deficient diamond-blackfan anemia using inducible expression of siRNA against RPS19. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 627-37. PMID 15771965 DOI: 10.1016/j.ymthe.2004.12.001  0.44
2005 Turelli P, Trono D. Editing at the crossroad of innate and adaptive immunity. Science (New York, N.Y.). 307: 1061-5. PMID 15718460 DOI: 10.1126/science.1105964  0.44
2005 Ariumi Y, Turelli P, Masutani M, Trono D. DNA damage sensors ATM, ATR, DNA-PKcs, and PARP-1 are dispensable for human immunodeficiency virus type 1 integration. Journal of Virology. 79: 2973-8. PMID 15709017 DOI: 10.1128/JVI.79.5.2973-2978.2005  0.44
2005 Wiznerowicz M, Trono D. Harnessing HIV for therapy, basic research and biotechnology. Trends in Biotechnology. 23: 42-7. PMID 15629857 DOI: 10.1016/j.tibtech.2004.11.001  0.44
2005 Flygare J, Kiefer T, Miyake K, Utsugisawa T, Hamaguchi I, Da Costa L, Richter J, Davey EJ, Matsson H, Dahl N, Wiznerowicz M, Trono D, Karlsson S. Deficiency of ribosomal protein S19 in CD34+ cells generated by siRNA blocks erythroid development and mimics defects seen in Diamond-Blackfan anemia. Blood. 105: 4627-34. PMID 15626736 DOI: 10.1182/blood-2004-08-3115  0.44
2004 Pham HM, Argañaraz ER, Groschel B, Trono D, Lama J. Lentiviral vectors interfering with virus-induced CD4 down-modulation potently block human immunodeficiency virus type 1 replication in primary lymphocytes. Journal of Virology. 78: 13072-81. PMID 15542659 DOI: 10.1128/JVI.78.23.13072-13081.2004  0.44
2004 An P, Bleiber G, Duggal P, Nelson G, May M, Mangeat B, Alobwede I, Trono D, Vlahov D, Donfield S, Goedert JJ, Phair J, Buchbinder S, O'Brien SJ, Telenti A, et al. APOBEC3G genetic variants and their influence on the progression to AIDS. Journal of Virology. 78: 11070-6. PMID 15452227 DOI: 10.1128/JVI.78.20.11070-11076.2004  0.44
2004 Arrighi JF, Pion M, Wiznerowicz M, Geijtenbeek TB, Garcia E, Abraham S, Leuba F, Dutoit V, Ducrey-Rundquist O, van Kooyk Y, Trono D, Piguet V. Lentivirus-mediated RNA interference of DC-SIGN expression inhibits human immunodeficiency virus transmission from dendritic cells to T cells. Journal of Virology. 78: 10848-55. PMID 15452205 DOI: 10.1128/JVI.78.20.10848-10855.2004  0.44
2004 Ciuffi A, Bleiber G, Muñoz M, Martinez R, Loeuillet C, Rehr M, Fischer M, Günthard HF, Oxenius A, Meylan P, Bonhoeffer S, Trono D, Telenti A. Entry and transcription as key determinants of differences in CD4 T-cell permissiveness to human immunodeficiency virus type 1 infection. Journal of Virology. 78: 10747-54. PMID 15367641 DOI: 10.1128/JVI.78.19.10747-10754.2004  0.44
2004 Turelli P, Vianin S, Trono D. The innate antiretroviral factor APOBEC3G does not affect human LINE-1 retrotransposition in a cell culture assay. The Journal of Biological Chemistry. 279: 43371-3. PMID 15322092 DOI: 10.1074/jbc.C400334200  0.44
2004 Trono D. Retroviruses under editing crossfire: a second member of the human APOBEC3 family is a Vif-blockable innate antiretroviral factor. Embo Reports. 5: 679-80. PMID 15229643 DOI: 10.1038/sj.embor.7400192  0.44
2004 Fauré J, Stalder R, Borel C, Sobo K, Piguet V, Demaurex N, Gruenberg J, Trono D. ARF1 regulates Nef-induced CD4 degradation. Current Biology : Cb. 14: 1056-64. PMID 15202998 DOI: 10.1016/j.cub.2004.06.021  0.44
2004 Bobardt MD, Salmon P, Wang L, Esko JD, Gabuzda D, Fiala M, Trono D, Van der Schueren B, David G, Gallay PA. Contribution of proteoglycans to human immunodeficiency virus type 1 brain invasion. Journal of Virology. 78: 6567-84. PMID 15163749 DOI: 10.1128/JVI.78.12.6567-6584.2004  0.44
2004 Turelli P, Mangeat B, Jost S, Vianin S, Trono D. Inhibition of hepatitis B virus replication by APOBEC3G. Science (New York, N.Y.). 303: 1829. PMID 15031497 DOI: 10.1126/science.1092066  0.44
2004 Mangeat B, Turelli P, Liao S, Trono D. A single amino acid determinant governs the species-specific sensitivity of APOBEC3G to Vif action. The Journal of Biological Chemistry. 279: 14481-3. PMID 14966139 DOI: 10.1074/jbc.C400060200  0.44
2003 Cudré-Mauroux C, Occhiodoro T, König S, Salmon P, Bernheim L, Trono D. Lentivector-mediated transfer of Bmi-1 and telomerase in muscle satellite cells yields a duchenne myoblast cell line with long-term genotypic and phenotypic stability. Human Gene Therapy. 14: 1525-33. PMID 14577914 DOI: 10.1089/104303403322495034  0.44
2003 Wiznerowicz M, Trono D. Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference. Journal of Virology. 77: 8957-61. PMID 12885912 DOI: 10.1128/JVI.77.16.8957-8951.2003  0.44
2003 Mangeat B, Turelli P, Caron G, Friedli M, Perrin L, Trono D. Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts Nature. 424: 99-103. PMID 12808466 DOI: 10.1038/nature01709  0.44
2003 Trono D. Picking the right spot Science. 300: 1670-1671. PMID 12805525 DOI: 10.1126/science.1086238  0.44
2003 Ritz-Laser B, Gauthier BR, Estreicher A, Mamin A, Brun T, Ris F, Salmon P, Halban PA, Trono D, Philippe J. Ectopic expression of the beta-cell specific transcription factor Pdx1 inhibits glucagon gene transcription Diabetologia. 46: 810-821. PMID 12783165 DOI: 10.1007/s00125-003-1115-7  0.44
2003 Kostic C, Chiodini F, Salmon P, Wiznerowicz M, Deglon N, Hornfeld D, Trono D, Aebischer P, Schorderet DF, Munier FL, Arsenijevic Y. Activity analysis of housekeeping promoters using self-inactivating lentiviral vector delivery into the mouse retina. Gene Therapy. 10: 818-21. PMID 12704422 DOI: 10.1038/sj.gt.3301948  0.44
2003 Caton D, Calabrese A, Mas C, Serre-Beinier V, Charollais A, Caille D, Zufferey R, Trono D, Meda P. Lentivirus-mediated transduction of connexin cDNAs shows level- and isoform-specific alterations in insulin secretion of primary pancreatic beta-cells. Journal of Cell Science. 116: 2285-94. PMID 12697840 DOI: 10.1242/jcs.00442  0.44
2003 Peterlin BM, Trono D. Hide, shield and strike back: How HIV-infected cells avoid immune eradication Nature Reviews Immunology. 3: 97-107. PMID 12563294 DOI: 10.1038/nri998  0.44
2003 Verhoeyen E, Dardalhon V, Ducrey-Rundquist O, Trono D, Taylor N, Cosset FL. IL-7 surface-engineered lentiviral vectors promote survival and efficient gene transfer in resting primary T lymphocytes Blood. 101: 2167-2174. PMID 12446448 DOI: 10.1182/blood-2002-07-2224  0.44
2003 Bovia F, Salmon P, Matthes T, Kvell K, Nguyen TH, Werner-Favre C, Barnet M, Nagy M, Leuba F, Arrighi JF, Piguet V, Trono D, Zubler RH. Efficient transduction of primary human B lymphocytes and nondividing myeloma B cells with HIV-1-derived lentiviral vectors. Blood. 101: 1727-33. PMID 12406892 DOI: 10.1182/blood-2001-12-0249  0.44
2003 Woods NB, Muessig A, Schmidt M, Flygare J, Olsson K, Salmon P, Trono D, von Kalle C, Karlsson S. Lentiviral vector transduction of NOD/SCID repopulating cells results in multiple vector integrations per transduced cell: risk of insertional mutagenesis. Blood. 101: 1284-9. PMID 12393514 DOI: 10.1182/blood-2002-07-2238  0.44
2002 Guyader M, Kiyokawa E, Abrami L, Turelli P, Trono D. Role for human immunodeficiency virus type 1 membrane cholesterol in viral internalization Journal of Virology. 76: 10356-10364. PMID 12239312 DOI: 10.1128/JVI.76.20.10356-10364.2002  0.44
2002 Vilhardt F, Plastre O, Sawada M, Suzuki K, Wiznerowicz M, Kiyokawa E, Trono D, Krause KH. The HIV-1 Nef protein and phagocyte NADPH oxidase activation Journal of Biological Chemistry. 277: 42136-42143. PMID 12207012 DOI: 10.1074/jbc.M200862200  0.44
2002 Ducrey-Rundquist O, Guyader M, Trono D. Modalities of interleukin-7-induced human immunodeficiency virus permissiveness in quiescent T lymphocytes Journal of Virology. 76: 9103-9111. PMID 12186894 DOI: 10.1128/JVI.76.18.9103-9111.2002  0.44
2002 Nguyen TH, Oberholzer J, Birraux J, Majno P, Morel P, Trono D. Highly efficient lentiviral vector-mediated transduction of nondividing, fully reimplantable primary hepatocytes Molecular Therapy. 6: 199-209. PMID 12161186 DOI: 10.1006/mthe.2002.0653  0.44
2002 Sandrin V, Boson B, Salmon P, Gay W, Nègre D, Le Grand R, Trono D, Cosset FL. Lentiviral vectors pseudotyped with a modified RD114 envelope glycoprotein show increased stability in sera and augmented transduction of primary lymphocytes and CD34+ cells derived from human and nonhuman primates. Blood. 100: 823-32. PMID 12130492 DOI: 10.1182/blood-2001-11-0042  0.44
2002 Fotopoulos G, Harari A, Michetti P, Trono D, Pantaleo G, Kraehenbuhl JP. Transepithelial transport of HIV-1 by M cells is receptor-mediated Proceedings of the National Academy of Sciences of the United States of America. 99: 9410-9414. PMID 12093918 DOI: 10.1073/pnas.142586899  0.44
2002 Lundberg C, Englund U, Trono D, Björklund A, Wictorin K. Differentiation of the RN33B cell line into forebrain projection neurons after transplantation into the neonatal rat brain. Experimental Neurology. 175: 370-87. PMID 12061867 DOI: 10.1006/exnr.2002.7888  0.44
2002 Maurice M, Verhoeyen E, Salmon P, Trono D, Russell SJ, Cosset FL. Efficient gene transfer into human primary blood lymphocytes by surface-engineered lentiviral vectors that display a T cell-activating polypeptide Blood. 99: 2342-2350. PMID 11895766 DOI: 10.1182/blood.V99.7.2342  0.44
2002 Salmon P, Trono D. Lentiviral vectors for the gene therapy of lympho-hematological disorders Current Topics in Microbiology and Immunology. 261: 211-227. PMID 11892249  0.44
2001 Peng KW, Pham L, Ye H, Zufferey R, Trono D, Cosset FL, Russell SJ. Organ distribution of gene expression after intravenous infusion of targeted and untargeted lentiviral vectors. Gene Therapy. 8: 1456-63. PMID 11593358 DOI: 10.1038/sj.gt.3301552  0.44
2001 Berton M, Turelli P, Trono D, Stein CA, Allémann E, Gurny R. Inhibition of HIV-1 in cell culture by oligonucleotide-loaded nanoparticles. Pharmaceutical Research. 18: 1096-101. PMID 11587479 DOI: 10.1023/A:1010962507273  0.32
2001 Salmon P, Arrighi JF, Piguet V, Chapuis B, Zubler RH, Trono D, Kindler V. Transduction of CD34+ cells with lentiviral vectors enables the production of large quantities of transgene-expressing immature and mature dendritic cells Journal of Gene Medicine. 3: 311-320. PMID 11529660 DOI: 10.1002/1521-2254(200107/08)3:4<311::AID-JGM198>3.0.CO;2-B  0.44
2001 Turelli P, Doucas V, Craig E, Mangeat B, Klages N, Evans R, Kalpana G, Trono D. Cytoplasmic recruitment of INI1 and PML on incoming HIV preintegration complexes: Interference with early steps of viral replication Molecular Cell. 7: 1245-1254. PMID 11430827 DOI: 10.1016/S1097-2765(01)00255-6  0.44
2001 Woods NB, Mikkola H, Nilsson E, Olsson K, Trono D, Karlsson S. Lentiviral-mediated gene transfer into haematopoietic stem cells. Journal of Internal Medicine. 249: 339-43. PMID 11298854 DOI: 10.1046/j.1365-2796.2001.00806.x  0.44
2001 Piguet V, Trono D. Living in oblivion: HIV immune evasion Seminars in Immunology. 13: 51-57. PMID 11289799 DOI: 10.1006/smim.2000.0295  0.44
2000 Englund U, Ericson C, Rosenblad C, Mandel RJ, Trono D, Wictorin K, Lundberg C. The use of a recombinant lentiviral vector for ex vivo gene transfer into the rat CNS. Neuroreport. 11: 3973-7. PMID 11192612  0.44
2000 Mikkola H, Woods NB, Sjögren M, Helgadottir H, Hamaguchi I, Jacobsen SE, Trono D, Karlsson S. Lentivirus gene transfer in murine hematopoietic progenitor cells is compromised by a delay in proviral integration and results in transduction mosaicism and heterogeneous gene expression in progeny cells. Journal of Virology. 74: 11911-8. PMID 11090191 DOI: 10.1128/JVI.74.24.11911-11918.2000  0.44
2000 Woods NB, Fahlman C, Mikkola H, Hamaguchi I, Olsson K, Zufferey R, Jacobsen SE, Trono D, Karlsson S. Lentiviral gene transfer into primary and secondary NOD/SCID repopulating cells. Blood. 96: 3725-33. PMID 11090053  0.44
2000 Diaz RM, Bateman A, Emiliusen L, Fielding A, Trono D, Russell SJ, Vile RG. A lentiviral vector expressing a fusogenic glycoprotein for cancer gene therapy. Gene Therapy. 7: 1656-63. PMID 11083474 DOI: 10.1038/sj.gt.3301277  0.44
2000 Salmon P, Kindler V, Ducrey O, Chapuis B, Zubler RH, Trono D. High-level transgene expression in human hematopoietic progenitors and differentiated blood lineages after transduction with improved lentiviral vectors Blood. 96: 3392-3398. PMID 11071633  0.44
2000 Doms RW, Trono D. The plasma membrane as a combat zone in the HIV battlefield Genes and Development. 14: 2677-2688. PMID 11069884 DOI: 10.1101/gad.833300  0.44
2000 Kordower JH, Emborg ME, Bloch J, Ma SY, Chu Y, Leventhal L, McBride J, Chen EY, Palfi S, Roitberg BZ, Brown WD, Holden JE, Pyzalski R, Taylor MD, Carvey P, ... ... Trono D, et al. Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease. Science (New York, N.Y.). 290: 767-73. PMID 11052933 DOI: 10.1126/science.290.5492.767  0.44
2000 Saulnier SO, Steinhoff D, Dinauer MC, Zufferey R, Trono D, Seger RA, Hossle JP. Lentivirus-mediated gene transfer of gp91phox corrects chronic granulomatous disease (CGD) phenotype in human X-CGD cells. The Journal of Gene Medicine. 2: 317-25. PMID 11045425 DOI: 10.1002/1521-2254(200009/10)2:5<317::AID-JGM127>3.0.CO;2-P  0.44
2000 Hamaguchi I, Woods NB, Panagopoulos I, Andersson E, Mikkola H, Fahlman C, Zufferey R, Carlsson L, Trono D, Karlsson S. Lentivirus vector gene expression during ES cell-derived hematopoietic development in vitro. Journal of Virology. 74: 10778-84. PMID 11044122 DOI: 10.1128/JVI.74.22.10778-10784.2000  0.44
2000 Salmon P, Oberholzer J, Occhiodoro T, Morel P, Lou J, Trono D. Reversible immortalization of human primary cells by lentivector-mediated transfer of specific genes Molecular Therapy. 2: 404-414. PMID 11020357 DOI: 10.1006/mthe.2000.0141  0.44
2000 Klages N, Zufferey R, Trono D. A stable system for the high-titer production of multiply attenuated lentiviral vectors Molecular Therapy. 2: 170-176. PMID 10947945 DOI: 10.1006/mthe.2000.0103  0.44
2000 Bosch A, Perret E, Desmaris N, Trono D, Heard JM. Reversal of pathology in the entire brain of mucopolysaccharidosis type VII mice after lentivirus-mediated gene transfer. Human Gene Therapy. 11: 1139-50. PMID 10834616 DOI: 10.1089/10430340050015194  0.44
2000 Piguet V, Wan L, Borel C, Mangasarian A, Demaurex N, Thomas G, Trono D. HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes Nature Cell Biology. 2: 163-167. PMID 10707087 DOI: 10.1038/35004038  0.44
2000 Rosenblad C, Grønborg M, Hansen C, Blom N, Meyer M, Johansen J, Dagø L, Kirik D, Patel UA, Lundberg C, Trono D, Björklund A, Johansen TE. In vivo protection of nigral dopamine neurons by lentiviral gene transfer of the novel GDNF-family member neublastin/artemin. Molecular and Cellular Neurosciences. 15: 199-214. PMID 10673327 DOI: 10.1006/mcne.1999.0817  0.44
2000 Déglon N, Tseng JL, Bensadoun JC, Zurn AD, Arsenijevic Y, De Almeida LP, Zufferey R, Trono D, Aebischer P. Self-inactivating lentiviral vectors with enhanced transgene expression as potential gene transfer system in Parkinson's disease Human Gene Therapy. 11: 179-190. PMID 10646649 DOI: 10.1089/10430340050016256  0.44
2000 Wang JK, Kiyokawa E, Verdin E, Trono D. The Nef protein of HIV-1 associates with rafts and primes T cells for activation Proceedings of the National Academy of Sciences of the United States of America. 97: 394-399. PMID 10618429 DOI: 10.1073/pnas.97.1.394  0.44
2000 Woods NB, Mikkola H, Hamaguchi I, Olsson K, Zufferey R, Jacobsen SE, Trono D, Karlsson S. Lentiviral gene transfer into nod/scid repopulating cells results in monoclonal hematopoiesis with transduced myeloid and lymphoid progeny Blood. 96: 218a.  0.44
1999 Dupraz P, Rinsch C, Pralong WF, Rolland E, Zufferey R, Trono D, Thorens B. Lentivirus-mediated Bcl-2 expression in βTC-tet cells improves resistance to hypoxia and cytokine-induced apoptosis while preserving in vitro and in vivo control of insulin secretion Gene Therapy. 6: 1160-1169. PMID 10455420 DOI: 10.1038/sj.gt.3300922  0.44
1999 Han JJ, Mhatre AN, Wareing M, Pettis R, Gao WQ, Zufferey RN, Trono D, Lalwani AK. Transgene expression in the guinea pig cochlea mediated by a lentivirus-derived gene transfer vector. Human Gene Therapy. 10: 1867-73. PMID 10446926 DOI: 10.1089/10430349950017545  0.44
1997 Zufferey R, Nagy D, Mandel RJ, Naldini L, Trono D. Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo. Nature Biotechnology. 15: 871-5. PMID 9306402 DOI: 10.1038/nbt0997-871  0.44
1997 Blömer U, Naldini L, Kafri T, Trono D, Verma IM, Gage FH. Highly efficient and sustained gene transfer in adult neurons with a lentivirus vector. Journal of Virology. 71: 6641-9. PMID 9261386  0.44
1997 Foti M, Carpentier JL, Aiken C, Trono D, Lew DP, Krause KH. Second-messenger regulation of receptor association with clathrin- coated pits: A novel and selective mechanism in the control of CD4 endocytosis Molecular Biology of the Cell. 8: 1377-1389. PMID 9243514 DOI: 10.1091/mbc.8.7.1377  0.44
1997 Gulizia RJ, Collman RG, Levy JA, Trono D, Mosier DE. Deletion of nef slows but does not prevent CD4-positive T-cell depletion in human immunodeficiency virus type 1-infected human-PBL-SCID mice. Journal of Virology. 71: 4161-4. PMID 9094701  0.32
1997 Mangasarian A, Foti M, Aiken C, Chin D, Carpentier JL, Trono D. The HIV-1 net protein acts as a connector with sorting pathways in the Golgi and at the plasma membrane Immunity. 6: 67-77. PMID 9052838 DOI: 10.1016/S1074-7613(00)80243-5  0.44
1996 Naldini L, Blömer U, Gage FH, Trono D, Verma IM. Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector. Proceedings of the National Academy of Sciences of the United States of America. 93: 11382-8. PMID 8876144 DOI: 10.1073/pnas.93.21.11382  0.44
1996 Blömer U, Naldini L, Verma IM, Trono D, Gage FH. Applications of gene therapy to the CNS. Human Molecular Genetics. 5: 1397-404. PMID 8875243  0.44
1996 Naldini L, Blömer U, Gallay P, Ory D, Mulligan R, Gage FH, Verma IM, Trono D. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science (New York, N.Y.). 272: 263-7. PMID 8602510  0.44
1996 Aiken C, Krause L, Chen YL, Trono D. Mutational analysis of HIV-1 Nef: Identification of two mutants that are temperature-sensitive for CD4 downregulation Virology. 217: 293-300. PMID 8599214 DOI: 10.1006/viro.1996.0116  0.44
1995 Gallay P, Swingler S, Aiken C, Trono D. HIV-1 infection of nondividing cells: C-terminal tyrosine phosphorylation of the viral matrix protein is a key regulator Cell. 80: 379-388. PMID 7859280 DOI: 10.1016/0092-8674(95)90488-3  0.44
1994 Aiken C, Konner J, Landau NR, Lenburg ME, Trono D. Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain. Cell. 76: 853-64. PMID 8124721 DOI: 10.1016/0092-8674(94)90360-3  0.44
1993 Winslow BJ, Pomerantz RJ, Bagasra O, Trono D. HIV-1 latency due to the site of proviral integration. Virology. 196: 849-54. PMID 8372452 DOI: 10.1006/viro.1993.1545  0.44
1990 Andino R, Rieckhof GE, Trono D, Baltimore D. Substitutions in the protease (3Cpro) gene of poliovirus can suppress a mutation in the 5' noncoding region. Journal of Virology. 64: 607-12. PMID 2153227  0.44
1988 Trono D, Andino R, Baltimore D. An RNA sequence of hundreds of nucleotides at the 5' end of poliovirus RNA is involved in allowing viral protein synthesis Journal of Virology. 62: 2291-2299. PMID 2836612  0.44
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