☰

Irving C. Allen, Ph.D. - Publications

Affiliations: 
2006 University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Genetics, Animal Physiology Biology, Molecular Biology, Neuroscience Biology, Pathology
Tree Info Grants Similar researchers PubMed Report error

67 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Callahan V, Hawks S, Crawford MA, Lehman CW, Morrison HA, Ivester HM, Akhrymuk I, Boghdeh N, Flor R, Finkielstein CV, Allen IC, Weger-Lucarelli J, Duggal N, Hughes MA, Kehn-Hall K. The Pro-Inflammatory Chemokines CXCL9, CXCL10 and CXCL11 Are Upregulated Following SARS-CoV-2 Infection in an AKT-Dependent Manner. Viruses. 13. PMID 34205098 DOI: 10.3390/v13061062  0.329
2020 Tupik JD, Coutermarsh-Ott SL, Benton AH, King KA, Kiryluk HD, Caswell CC, Allen IC. ASC-Mediated Inflammation and Pyroptosis Attenuates Pathogenesis Following the Recognition of gDNA. Pathogens (Basel, Switzerland). 9. PMID 33266295 DOI: 10.3390/pathogens9121008  0.337
2020 Brock RM, Beitel-White N, Davalos RV, Allen IC. Starting a Fire Without Flame: The Induction of Cell Death and Inflammation in Electroporation-Based Tumor Ablation Strategies. Frontiers in Oncology. 10: 1235. PMID 32850371 DOI: 10.3389/Fonc.2020.01235  0.306
2020 Tupik JD, Nagai-Singer MA, Allen IC. To protect or adversely affect? The dichotomous role of the NLRP1 inflammasome in human disease. Molecular Aspects of Medicine. 100858. PMID 32359693 DOI: 10.1016/J.Mam.2020.100858  0.408
2019 McDaniel DK, Ringel-Scaia VM, Morrison HA, Coutermarsh-Ott S, Council-Troche M, Angle JW, Perry JB, Davis G, Leng W, Minarchick V, Yang Y, Chen B, Reece SW, Brown DA, Cecere TE, ... ... Allen IC, et al. Pulmonary Exposure to Magnéli Phase Titanium Suboxides Results in Significant Macrophage Abnormalities and Decreased Lung Function. Frontiers in Immunology. 10: 2714. PMID 31849940 DOI: 10.3389/Fimmu.2019.02714  0.383
2019 Beitel-White N, Martin RCG, Li Y, Brock RM, Allen IC, Davalos RV. Real-time prediction of patient immune cell modulation during irreversible electroporation therapy. Scientific Reports. 9: 17739. PMID 31780711 DOI: 10.1038/S41598-019-53974-W  0.303
2019 Nagai-Singer MA, Morrison HA, Allen IC. NLRX1 Is a Multifaceted and Enigmatic Regulator of Immune System Function. Frontiers in Immunology. 10: 2419. PMID 31681307 DOI: 10.3389/Fimmu.2019.02419  0.424
2019 Hazy A, Bochicchio L, Oliver A, Xie E, Geng S, Brickler T, Xie H, Li L, Allen IC, Theus MH. Divergent age-dependent peripheral immune transcriptomic profile following traumatic brain injury. Scientific Reports. 9: 8564. PMID 31189983 DOI: 10.1038/S41598-019-45089-Z  0.354
2019 McDaniel DK, Allen IC. Using Klebsiella pneumoniae to Model Acute Lung Inflammation in Mice. Methods in Molecular Biology (Clifton, N.J.). 1960: 169-180. PMID 30798531 DOI: 10.1007/978-1-4939-9167-9_15  0.444
2019 Ringel-Scaia VM, Powell MD, Read KA, Allen IC, Oestreich KJ. Systemic Listeria monocytogenes Infection as a Model to Study T Helper Cell Immune Responses. Methods in Molecular Biology (Clifton, N.J.). 1960: 149-160. PMID 30798529 DOI: 10.1007/978-1-4939-9167-9_13  0.33
2019 Ringel-Scaia VM, Qin Y, Thomas CA, Huie KE, McDaniel DK, Eden K, Wade PA, Allen IC. Maternal Influence and Murine Housing Confound Impact of NLRP1 Inflammasome on Microbiome Composition. Journal of Innate Immunity. 1-16. PMID 30759441 DOI: 10.1159/000495850  0.324
2018 Lebovitz Y, Ringel-Scaia VM, Allen IC, Theus MH. Emerging Developments in Microbiome and Microglia Research: Implications for Neurodevelopmental Disorders. Frontiers in Immunology. 9: 1993. PMID 30233586 DOI: 10.3389/Fimmu.2018.01993  0.304
2018 Rothschild DE, McDaniel DK, Ringel-Scaia VM, Allen IC. Modulating inflammation through the negative regulation of NF-κB signaling. Journal of Leukocyte Biology. PMID 29389019 DOI: 10.1002/Jlb.3Mir0817-346Rrr  0.381
2017 Eden K, Rothschild DE, McDaniel DK, Heid B, Allen IC. Noncanonical NF-κB signaling and the essential kinase NIK modulate crucial features associated with eosinophilic esophagitis pathogenesis. Disease Models & Mechanisms. 10: 1517-1527. PMID 29259025 DOI: 10.1242/Dmm.030767  0.408
2017 Mu Q, Tavella VJ, Kirby JL, Cecere TE, Chung M, Lee J, Li S, Ahmed SA, Eden K, Allen IC, Reilly CM, Luo XM. Antibiotics ameliorate lupus-like symptoms in mice. Scientific Reports. 7: 13675. PMID 29057975 DOI: 10.1038/S41598-017-14223-0  0.384
2017 Theus MH, Brickler T, Meza AL, Coutermarsh-Ott S, Hazy A, Gris D, Allen IC. Loss of NLRX1 Exacerbates Neural Tissue Damage and NF-κB Signaling following Brain Injury. Journal of Immunology (Baltimore, Md. : 1950). PMID 28993512 DOI: 10.4049/Jimmunol.1700251  0.323
2017 Read KA, Powell MD, Baker CE, Sreekumar BK, Ringel-Scaia VM, Bachus H, Martin RE, Cooley ID, Allen IC, Ballesteros-Tato A, Oestreich KJ. Integrated STAT3 and Ikaros Zinc Finger Transcription Factor Activities Regulate Bcl-6 Expression in CD4(+) Th Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 28848064 DOI: 10.4049/Jimmunol.1700106  0.328
2017 Leber A, Hontecillas R, Tubau-Juni N, Zoccoli-Rodriguez V, Hulver M, McMillan R, Eden K, Allen IC, Bassaganya-Riera J. NLRX1 Regulates Effector and Metabolic Functions of CD4+ T Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 28159898 DOI: 10.4049/Jimmunol.1601547  0.385
2016 Ringel-Scaia VM, McDaniel DK, Allen IC. The Goldilocks Conundrum: NLR Inflammasome Modulation of Gastrointestinal Inflammation during Inflammatory Bowel Disease. Critical Reviews in Immunology. 36: 283-314. PMID 28322135 DOI: 10.1615/Critrevimmunol.2017019158  0.449
2016 Rothschild DE, Zhang Y, Diao N, Lee CK, Chen K, Caswell CC, Slade DJ, Helm RF, LeRoith T, Li L, Allen IC. Enhanced Mucosal Defense and Reduced Tumor Burden in Mice with the Compromised Negative Regulator IRAK-M. Ebiomedicine. PMID 27939424 DOI: 10.1016/J.Ebiom.2016.11.039  0.375
2016 Goswami I, Coutermarsh-Ott S, Morrison RG, Allen IC, Davalos RV, Verbridge SS, Bickford LR. Irreversible electroporation inhibits pro-cancer inflammatory signaling in triple negative breast cancer cells. Bioelectrochemistry (Amsterdam, Netherlands). 113: 42-50. PMID 27693939 DOI: 10.1016/J.Bioelechem.2016.09.003  0.352
2016 Holl EK, Allen IC, Martinez J. Holding the Inflammatory System in Check: TLRs and NLRs. Mediators of Inflammation. 2016: 8156816. PMID 27642239 DOI: 10.1155/2016/8156816  0.389
2016 McDaniel DK, Eden K, Ringel VM, Allen IC. Emerging Roles for Noncanonical NF-κB Signaling in the Modulation of Inflammatory Bowel Disease Pathobiology. Inflammatory Bowel Diseases. PMID 27508514 DOI: 10.1097/Mib.0000000000000858  0.362
2016 Coutermarsh-Ott SL, Doran JT, Campbell C, Williams TM, Lindsay DS, Allen IC. Caspase-11 Modulates Inflammation and Attenuates Toxoplasma gondii Pathogenesis. Mediators of Inflammation. 2016: 9848263. PMID 27378827 DOI: 10.1155/2016/9848263  0.388
2016 Wang H, Gao K, Wen K, Allen IC, Li G, Zhang W, Kocher J, Yang X, Giri-Rachman E, Li GH, Clark-Deener S, Yuan L. Lactobacillus rhamnosus GG modulates innate signaling pathway and cytokine responses to rotavirus vaccine in intestinal mononuclear cells of gnotobiotic pigs transplanted with human gut microbiota. Bmc Microbiology. 16: 109. PMID 27301272 DOI: 10.1186/S12866-016-0727-2  0.307
2016 Rothschild DE, Srinivasan T, Aponte-Santiago LA, Shen X, Allen IC. The Ex Vivo Culture and Pattern Recognition Receptor Stimulation of Mouse Intestinal Organoids. Journal of Visualized Experiments : Jove. PMID 27285214 DOI: 10.3791/54033  0.327
2016 Brickler T, Gresham K, Meza A, Coutermarsh-Ott S, Williams TM, Rothschild DE, Allen IC, Theus MH. Nonessential Role for the NLRP1 Inflammasome Complex in a Murine Model of Traumatic Brain Injury. Mediators of Inflammation. 2016: 6373506. PMID 27199506 DOI: 10.1155/2016/6373506  0.318
2016 Coutermarsh-Ott S, Simmons A, Capria V, LeRoith T, Wilson JE, Heid B, Philipson CW, Qin Q, Hontecillas-Magarzo R, Bassaganya-Riera J, Ting JP, Dervisis N, Allen IC. NLRX1 suppresses tumorigenesis and attenuates histiocytic sarcoma through the negative regulation of NF-κB signaling. Oncotarget. PMID 27105514 DOI: 10.18632/Oncotarget.8861  0.367
2016 Coutermarsh-Ott S, Eden K, Allen IC. Beyond the inflammasome: regulatory NOD-like receptor modulation of the host immune response following virus exposure. The Journal of General Virology. 97: 825-38. PMID 26763980 DOI: 10.1099/Jgv.0.000401  0.403
2015 Williams TM, Leeth RA, Rothschild DE, Coutermarsh-Ott SL, McDaniel DK, Simmons AE, Heid B, Cecere TE, Allen IC. The NLRP1 inflammasome attenuates colitis and colitis-associated tumorigenesis. Journal of Immunology (Baltimore, Md. : 1950). 194: 3369-80. PMID 25725098 DOI: 10.4049/Jimmunol.1402098  0.438
2015 Williams TM, Leeth RA, Rothschild DE, McDaniel DK, Coutermarsh-Ott SL, Simmons AE, Kable KH, Heid B, Allen IC. Caspase-11 attenuates gastrointestinal inflammation and experimental colitis pathogenesis. American Journal of Physiology. Gastrointestinal and Liver Physiology. 308: G139-50. PMID 25414099 DOI: 10.1152/Ajpgi.00234.2014  0.416
2014 Davis BK, Philipson C, Hontecillas R, Eden K, Bassaganya-Riera J, Allen IC. Emerging significance of NLRs in inflammatory bowel disease. Inflammatory Bowel Diseases. 20: 2412-32. PMID 25153506 DOI: 10.1097/Mib.0000000000000151  0.435
2014 Allen IC. Non-Inflammasome Forming NLRs in Inflammation and Tumorigenesis. Frontiers in Immunology. 5: 169. PMID 24795716 DOI: 10.3389/fimmu.2014.00169  0.309
2014 Allen IC. The utilization of oropharyngeal intratracheal PAMP administration and bronchoalveolar lavage to evaluate the host immune response in mice. Journal of Visualized Experiments : Jove. PMID 24747836 DOI: 10.3791/51391  0.386
2014 Allen IC. Non-inflammasome forming NLRs in inflammation and tumorigenesis Frontiers in Immunology. 5. DOI: 10.3389/Fimmu.2014.00169  0.418
2013 Abdul-Sater AA, Tattoli I, Jin L, Grajkowski A, Levi A, Koller BH, Allen IC, Beaucage SL, Fitzgerald KA, Ting JP, Cambier JC, Girardin SE, Schindler C. Cyclic-di-GMP and cyclic-di-AMP activate the NLRP3 inflammasome. Embo Reports. 14: 900-6. PMID 24008845 DOI: 10.1038/Embor.2013.132  0.51
2013 Allen IC. Induction of allergic airway disease using house dust mite allergen. Methods in Molecular Biology (Clifton, N.J.). 1032: 159-72. PMID 23943452 DOI: 10.1007/978-1-62703-496-8_13  0.462
2013 Allen IC. Contact hypersensitivity models in mice. Methods in Molecular Biology (Clifton, N.J.). 1032: 139-44. PMID 23943450 DOI: 10.1007/978-1-62703-496-8_11  0.333
2013 Allen IC. Bacteria-mediated acute lung inflammation. Methods in Molecular Biology (Clifton, N.J.). 1031: 163-75. PMID 23824899 DOI: 10.1007/978-1-62703-481-4_19  0.444
2013 Allen IC. Delayed-type hypersensitivity models in mice. Methods in Molecular Biology (Clifton, N.J.). 1031: 101-7. PMID 23824893 DOI: 10.1007/978-1-62703-481-4_13  0.332
2013 Moore CB, Allen IC. Primary ear fibroblast derivation from mice. Methods in Molecular Biology (Clifton, N.J.). 1031: 65-70. PMID 23824888 DOI: 10.1007/978-1-62703-481-4_8  0.343
2013 Roberts RA, Shen T, Allen IC, Hasan W, DeSimone JM, Ting JP. Analysis of the murine immune response to pulmonary delivery of precisely fabricated nano- and microscale particles. Plos One. 8: e62115. PMID 23593509 DOI: 10.1371/Journal.Pone.0062115  0.347
2013 Allen IC, McElvania-TeKippe E, Wilson JE, Lich JD, Arthur JC, Sullivan JT, Braunstein M, Ting JP. Characterization of NLRP12 during the in vivo host immune response to Klebsiella pneumoniae and Mycobacterium tuberculosis. Plos One. 8: e60842. PMID 23577168 DOI: 10.1371/Journal.Pone.0060842  0.42
2012 Holl EK, Roney KE, Allen IC, Steinbach E, Arthur JC, Buntzman A, Plevy S, Frelinger J, Ting JP. Plexin-B2 and Plexin-D1 in dendritic cells: expression and IL-12/IL-23p40 production. Plos One. 7: e43333. PMID 22916243 DOI: 10.1371/Journal.Pone.0043333  0.325
2012 Schneider M, Zimmermann AG, Roberts RA, Zhang L, Swanson KV, Wen H, Davis BK, Allen IC, Holl EK, Ye Z, Rahman AH, Conti BJ, Eitas TK, Koller BH, Ting JP. The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB. Nature Immunology. 13: 823-31. PMID 22863753 DOI: 10.1038/Ni.2378  0.552
2012 Allen IC, Wilson JE, Schneider M, Lich JD, Roberts RA, Arthur JC, Woodford RM, Davis BK, Uronis JM, Herfarth HH, Jobin C, Rogers AB, Ting JP. NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling. Immunity. 36: 742-54. PMID 22503542 DOI: 10.1016/J.Immuni.2012.03.012  0.367
2012 Allen IC, Jania CM, Wilson JE, Tekeppe EM, Hua X, Brickey WJ, Kwan M, Koller BH, Tilley SL, Ting JP. Analysis of NLRP3 in the development of allergic airway disease in mice. Journal of Immunology (Baltimore, Md. : 1950). 188: 2884-93. PMID 22323538 DOI: 10.4049/Jimmunol.1102488  0.607
2012 Segovia J, Sabbah A, Mgbemena V, Tsai SY, Chang TH, Berton MT, Morris IR, Allen IC, Ting JP, Bose S. TLR2/MyD88/NF-κB pathway, reactive oxygen species, potassium efflux activates NLRP3/ASC inflammasome during respiratory syncytial virus infection. Plos One. 7: e29695. PMID 22295065 DOI: 10.1371/Journal.Pone.0029695  0.347
2012 Allen IC, Lich JD, Arthur JC, Jania CM, Roberts RA, Callaway JB, Tilley SL, Ting JP. Characterization of NLRP12 during the development of allergic airway disease in mice. Plos One. 7: e30612. PMID 22291998 DOI: 10.1371/Journal.Pone.0030612  0.517
2012 Kebaier C, Chamberland RR, Allen IC, Gao X, Broglie PM, Hall JD, Jania C, Doerschuk CM, Tilley SL, Duncan JA. Staphylococcus aureus α-hemolysin mediates virulence in a murine model of severe pneumonia through activation of the NLRP3 inflammasome. The Journal of Infectious Diseases. 205: 807-17. PMID 22279123 DOI: 10.1093/Infdis/Jir846  0.336
2012 Cyphert JM, Allen IC, Church RJ, Latour AM, Snouwaert JN, Coffman TM, Koller BH. Allergic inflammation induces a persistent mechanistic switch in thromboxane-mediated airway constriction in the mouse. American Journal of Physiology. Lung Cellular and Molecular Physiology. 302: L140-51. PMID 21984570 DOI: 10.1152/Ajplung.00152.2011  0.766
2011 Allen IC. A NOD to zebrafish models of inflammatory bowel disease pathogenesis. Disease Models & Mechanisms. 4: 711-2. PMID 22065838 DOI: 10.1242/Dmm.008805  0.316
2011 Allen IC, Moore CB, Schneider M, Lei Y, Davis BK, Scull MA, Gris D, Roney KE, Zimmermann AG, Bowzard JB, Ranjan P, Monroe KM, Pickles RJ, Sambhara S, Ting JP. NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-κB signaling pathways. Immunity. 34: 854-65. PMID 21703540 DOI: 10.1016/J.Immuni.2011.03.026  0.383
2011 Taxman DJ, Holley-Guthrie EA, Huang MT, Moore CB, Bergstralh DT, Allen IC, Lei Y, Gris D, Ting JP. The NLR adaptor ASC/PYCARD regulates DUSP10, mitogen-activated protein kinase (MAPK), and chemokine induction independent of the inflammasome. The Journal of Biological Chemistry. 286: 19605-16. PMID 21487011 DOI: 10.1074/Jbc.M111.221077  0.359
2010 van Deventer HW, Burgents JE, Wu QP, Woodford RM, Brickey WJ, Allen IC, McElvania-Tekippe E, Serody JS, Ting JP. The inflammasome component NLRP3 impairs antitumor vaccine by enhancing the accumulation of tumor-associated myeloid-derived suppressor cells. Cancer Research. 70: 10161-9. PMID 21159638 DOI: 10.1158/0008-5472.Can-10-1921  0.384
2010 Huang MT, Mortensen BL, Taxman DJ, Craven RR, Taft-Benz S, Kijek TM, Fuller JR, Davis BK, Allen IC, Brickey WJ, Gris D, Wen H, Kawula TH, Ting JP. Deletion of ripA alleviates suppression of the inflammasome and MAPK by Francisella tularensis. Journal of Immunology (Baltimore, Md. : 1950). 185: 5476-85. PMID 20921527 DOI: 10.4049/Jimmunol.1002154  0.349
2010 Arthur JC, Lich JD, Ye Z, Allen IC, Gris D, Wilson JE, Schneider M, Roney KE, O'Connor BP, Moore CB, Morrison A, Sutterwala FS, Bertin J, Koller BH, Liu Z, et al. Cutting edge: NLRP12 controls dendritic and myeloid cell migration to affect contact hypersensitivity. Journal of Immunology (Baltimore, Md. : 1950). 185: 4515-9. PMID 20861349 DOI: 10.4049/Jimmunol.1002227  0.58
2010 McElvania Tekippe E, Allen IC, Hulseberg PD, Sullivan JT, McCann JR, Sandor M, Braunstein M, Ting JP. Granuloma formation and host defense in chronic Mycobacterium tuberculosis infection requires PYCARD/ASC but not NLRP3 or caspase-1. Plos One. 5: e12320. PMID 20808838 DOI: 10.1371/Journal.Pone.0012320  0.324
2010 Allen IC, TeKippe EM, Woodford RM, Uronis JM, Holl EK, Rogers AB, Herfarth HH, Jobin C, Ting JP. The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer. The Journal of Experimental Medicine. 207: 1045-56. PMID 20385749 DOI: 10.1084/Jem.20100050  0.412
2010 Kwan M, Allen I, Brickey W, Hernandez M, Peden D, Ting J. The Nlrp3 Inflammasome Affects Airway Inflammation, IgE/IL-13 Production And Mast Cell Function In A Subchronic Model Of Asthma Journal of Allergy and Clinical Immunology. 125: AB237. DOI: 10.1016/J.Jaci.2009.12.927  0.404
2009 Allen IC. Searching for an improved mouse model of allergic airway disease using dual allergen exposures. Disease Models & Mechanisms. 2: 519-20. PMID 19892879 DOI: 10.1242/Dmm.004333  0.364
2009 Craven RR, Gao X, Allen IC, Gris D, Bubeck Wardenburg J, McElvania-Tekippe E, Ting JP, Duncan JA. Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells. Plos One. 4: e7446. PMID 19826485 DOI: 10.1371/Journal.Pone.0007446  0.368
2009 Willingham SB, Allen IC, Bergstralh DT, Brickey WJ, Huang MT, Taxman DJ, Duncan JA, Ting JP. NLRP3 (NALP3, Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasome-dependent and -independent pathways. Journal of Immunology (Baltimore, Md. : 1950). 183: 2008-15. PMID 19587006 DOI: 10.4049/Jimmunol.0900138  0.382
2009 Cyphert JM, Kovarova M, Allen IC, Hartney JM, Murphy DL, Wess J, Koller BH. Cooperation between mast cells and neurons is essential for antigen-mediated bronchoconstriction. Journal of Immunology (Baltimore, Md. : 1950). 182: 7430-9. PMID 19494266 DOI: 10.4049/Jimmunol.0900039  0.693
2009 Allen IC, Scull MA, Moore CB, Holl EK, McElvania-TeKippe E, Taxman DJ, Guthrie EH, Pickles RJ, Ting JP. The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. Immunity. 30: 556-65. PMID 19362020 DOI: 10.1016/J.Immuni.2009.02.005  0.303
2006 Allen IC, Pace AJ, Jania LA, Ledford JG, Latour AM, Snouwaert JN, Bernier V, Stocco R, Therien AG, Koller BH. Expression and function of NPSR1/GPRA in the lung before and after induction of asthma-like disease. American Journal of Physiology. Lung Cellular and Molecular Physiology. 291: L1005-17. PMID 16829631 DOI: 10.1152/Ajplung.00174.2006  0.76
2006 Allen IC, Hartney JM, Coffman TM, Penn RB, Wess J, Koller BH. Thromboxane A2 induces airway constriction through an M3 muscarinic acetylcholine receptor-dependent mechanism. American Journal of Physiology. Lung Cellular and Molecular Physiology. 290: L526-33. PMID 16243899 DOI: 10.1152/Ajplung.00340.2005  0.767
Show low-probability matches.