Year |
Citation |
Score |
2010 |
Nestler EJ, Hyman SE. Animal models of neuropsychiatric disorders. Nature Neuroscience. 13: 1161-9. PMID 20877280 DOI: 10.1038/Nn.2647 |
0.428 |
|
2008 |
Hyman SE. How might cocaine interfere with brain development? Plos Medicine. 5: e130. PMID 18547140 DOI: 10.1371/Journal.Pmed.0050130 |
0.326 |
|
2008 |
Paletzki RF, Myakishev MV, Polesskaya O, Orosz A, Hyman SE, Vinson C. Inhibiting activator protein-1 activity alters cocaine-induced gene expression and potentiates sensitization. Neuroscience. 152: 1040-53. PMID 18355967 DOI: 10.1016/J.Neuroscience.2008.01.045 |
0.391 |
|
2006 |
Hyman SE, Malenka RC, Nestler EJ. Neural mechanisms of addiction: the role of reward-related learning and memory. Annual Review of Neuroscience. 29: 565-98. PMID 16776597 DOI: 10.1146/Annurev.Neuro.29.051605.113009 |
0.47 |
|
2006 |
Hyman SE. Even chromatin gets the blues. Nature Neuroscience. 9: 465-6. PMID 16568101 DOI: 10.1038/Nn0406-465 |
0.302 |
|
2006 |
Sgambato-Faure V, Xiong Y, Berke JD, Hyman SE, Strehler EE. The Homer-1 protein Ania-3 interacts with the plasma membrane calcium pump. Biochemical and Biophysical Research Communications. 343: 630-7. PMID 16554037 DOI: 10.1016/J.Bbrc.2006.03.020 |
0.565 |
|
2005 |
Voulalas PJ, Holtzclaw L, Wolstenholme J, Russell JT, Hyman SE. Metabotropic glutamate receptors and dopamine receptors cooperate to enhance extracellular signal-regulated kinase phosphorylation in striatal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 3763-73. PMID 15829628 DOI: 10.1523/Jneurosci.4574-04.2005 |
0.325 |
|
2004 |
Montague PR, Hyman SE, Cohen JD. Computational roles for dopamine in behavioural control. Nature. 431: 760-7. PMID 15483596 DOI: 10.1038/Nature03015 |
0.301 |
|
2003 |
Sgambato V, Minassian R, Nairn AC, Hyman SE. Regulation of ania-6 splice variants by distinct signaling pathways in striatal neurons. Journal of Neurochemistry. 86: 153-64. PMID 12807435 DOI: 10.1046/J.1471-4159.2003.01816.X |
0.395 |
|
2001 |
Berke JD, Sgambato V, Zhu PP, Lavoie B, Vincent M, Krause M, Hyman SE. Dopamine and glutamate induce distinct striatal splice forms of Ania-6, an RNA polymerase II-associated cyclin. Neuron. 32: 277-87. PMID 11683997 DOI: 10.1016/S0896-6273(01)00465-2 |
0.61 |
|
2001 |
Kosofsky BE, Hyman SE. No time for complacency: the fetal brain on drugs. The Journal of Comparative Neurology. 435: 259-62. PMID 11406809 DOI: 10.1002/Cne.1027 |
0.557 |
|
2000 |
Hyman SE. Genes, gene expression, and behavior. Neurobiology of Disease. 7: 528-32. PMID 11042069 DOI: 10.1006/Nbdi.2000.0347 |
0.306 |
|
2000 |
Hyman SE. The genetics of mental illness: implications for practice. Bulletin of the World Health Organization. 78: 455-63. PMID 10885164 DOI: 10.1590/S0042-96862000000400007 |
0.322 |
|
2000 |
Berke JD, Hyman SE. Addiction, dopamine, and the molecular mechanisms of memory. Neuron. 25: 515-32. PMID 10774721 DOI: 10.1016/S0896-6273(00)81056-9 |
0.553 |
|
1999 |
Hyman SE. Selective gene expression increases behavioral sensitivity to cocaine. Nature Neuroscience. 2: 855-6. PMID 10491599 DOI: 10.1038/13147 |
0.342 |
|
1999 |
Kobierski LA, Wong AE, Srivastava S, Borsook D, Hyman SE. Cyclic AMP-dependent activation of the proenkephalin gene requires phosphorylation of CREB at serine-133 and a Src-related kinase. Journal of Neurochemistry. 73: 129-38. PMID 10386963 DOI: 10.1046/J.1471-4159.1999.0730129.X |
0.339 |
|
1999 |
Schwarzschild MA, Cole RL, Meyers MA, Hyman SE. Contrasting calcium dependencies of SAPK and ERK activations by glutamate in cultured striatal neurons. Journal of Neurochemistry. 72: 2248-55. PMID 10349832 DOI: 10.1046/J.1471-4159.1999.0722248.X |
0.309 |
|
1999 |
Van Koughnet K, Smirnova O, Hyman SE, Borsook D. Proenkephalin transgene regulation in the paraventricular nucleus of the hypothalamus by lipopolysaccharide and interleukin-1beta. The Journal of Comparative Neurology. 405: 199-215. PMID 10023810 DOI: 10.1002/(Sici)1096-9861(19990308)405:2<199::Aid-Cne5>3.0.Co;2-W |
0.306 |
|
1998 |
Genova LM, Hyman SE. 5-HT3 receptor activation is required for induction of striatal c-Fos and phosphorylation of ATF-1 by amphetamine. Synapse (New York, N.Y.). 30: 71-8. PMID 9704883 DOI: 10.1002/(Sici)1098-2396(199809)30:1<71::Aid-Syn9>3.0.Co;2-H |
0.345 |
|
1998 |
Fienberg AA, Hiroi N, Mermelstein PG, Song W, Snyder GL, Nishi A, Cheramy A, O'Callaghan JP, Miller DB, Cole DG, Corbett R, Haile CN, Cooper DC, Onn SP, Grace AA, ... ... Hyman SE, et al. DARPP-32: regulator of the efficacy of dopaminergic neurotransmission. Science (New York, N.Y.). 281: 838-42. PMID 9694658 DOI: 10.1126/Science.281.5378.838 |
0.506 |
|
1998 |
Berke JD, Paletzki RF, Aronson GJ, Hyman SE, Gerfen CR. A complex program of striatal gene expression induced by dopaminergic stimulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 5301-10. PMID 9651213 DOI: 10.1523/Jneurosci.18-14-05301.1998 |
0.639 |
|
1998 |
Berke JD, Paletzki RF, Aronson GJ, Hyman SE, Gerfen CR. A Complex Program of Striatal Gene Expression Induced by Dopaminergic Stimulation The Journal of Neuroscience. 18: 5301-5310. DOI: 10.1523/JNEUROSCI.18-14-05301.1998 |
0.548 |
|
1997 |
Genova L, Berke J, Hyman SE. Molecular adaptations to psychostimulants in striatal neurons: toward a pathophysiology of addiction. Neurobiology of Disease. 4: 239-46. PMID 9361300 DOI: 10.1006/Nbdi.1997.0154 |
0.572 |
|
1997 |
Breiter HC, Gollub RL, Weisskoff RM, Kennedy DN, Makris N, Berke JD, Goodman JM, Kantor HL, Gastfriend DR, Riorden JP, Mathew RT, Rosen BR, Hyman SE. Acute effects of cocaine on human brain activity and emotion. Neuron. 19: 591-611. PMID 9331351 DOI: 10.1016/S0896-6273(00)80374-8 |
0.576 |
|
1997 |
Schwarzschild MA, Cole RL, Hyman SE. Glutamate, but not dopamine, stimulates stress-activated protein kinase and AP-1-mediated transcription in striatal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 3455-66. PMID 9133371 DOI: 10.1523/Jneurosci.17-10-03455.1997 |
0.379 |
|
1997 |
Hyman S, Schwarzschild M, Cole R. Glutamate, but not dopamine stimulates AP-1 mediated transcription in striatal neurons Biological Psychiatry. 42: 149S-150S. DOI: 10.1016/S0006-3223(97)87503-8 |
0.332 |
|
1996 |
Berhow MT, Hiroi N, Kobierski LA, Hyman SE, Nestler EJ. Influence of cocaine on the JAK-STAT pathway in the mesolimbic dopamine system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 8019-26. PMID 8987828 DOI: 10.1523/Jneurosci.16-24-08019.1996 |
0.514 |
|
1996 |
Konradi C, Leveque JC, Hyman SE. Amphetamine and dopamine-induced immediate early gene expression in striatal neurons depends on postsynaptic NMDA receptors and calcium. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 4231-9. PMID 8753884 DOI: 10.1523/Jneurosci.16-13-04231.1996 |
0.645 |
|
1996 |
Hyman SE. Shaking out the cause of addiction. Science (New York, N.Y.). 273: 611-2. PMID 8701316 DOI: 10.1126/Science.273.5275.611 |
0.314 |
|
1996 |
Hyman SE. Addiction to cocaine and amphetamine. Neuron. 16: 901-4. PMID 8630246 DOI: 10.1016/S0896-6273(00)80111-7 |
0.393 |
|
1996 |
Hyman SE, Nestler EJ. Initiation and adaptation: a paradigm for understanding psychotropic drug action. The American Journal of Psychiatry. 153: 151-62. PMID 8561194 DOI: 10.1176/Ajp.153.2.151 |
0.478 |
|
1996 |
Breiter H, Berke J, Kennedy W, Rosen B, Hyman S. Activation of striatum and amygdala during reward conditioning: An FMRI study Neuroimage. 3: S220. DOI: 10.1016/S1053-8119(96)80222-9 |
0.55 |
|
1995 |
Kosofsky BE, Genova LM, Hyman SE. Postnatal age defines specificity of immediate early gene induction by cocaine in developing rat brain. The Journal of Comparative Neurology. 351: 27-40. PMID 7896938 DOI: 10.1002/Cne.903510104 |
0.644 |
|
1995 |
Cole RL, Konradi C, Douglass J, Hyman SE. Neuronal adaptation to amphetamine and dopamine: molecular mechanisms of prodynorphin gene regulation in rat striatum. Neuron. 14: 813-23. PMID 7718243 DOI: 10.1016/0896-6273(95)90225-2 |
0.664 |
|
1995 |
Konradi C, Cole RL, Green D, Senatus P, Leveque JC, Pollack AE, Grossbard SJ, Hyman SE. Analysis of the proenkephalin second messenger-inducible enhancer in rat striatal cultures. Journal of Neurochemistry. 65: 1007-15. PMID 7643080 DOI: 10.1046/J.1471-4159.1995.65031007.X |
0.629 |
|
1995 |
Hyman SE, Cole RL, Konradi C, Kosofsky BE. Dopamine regulation of transcription factor-target interactions in rat striatum. Chemical Senses. 20: 257-60. PMID 7583020 DOI: 10.1093/Chemse/20.2.257 |
0.747 |
|
1995 |
Borsook D, Hyman SE. Proenkephalin gene regulation in the neuroendocrine hypothalamus: a model of gene regulation in the CNS. The American Journal of Physiology. 269: E393-408. PMID 7573416 DOI: 10.1152/Ajpendo.1995.269.3.E393 |
0.356 |
|
1995 |
Kosofsky BE, Genova LM, Hyman SE. Substance P phenotype defines specificity of c-fos induction by cocaine in developing rat striatum. The Journal of Comparative Neurology. 351: 41-50. PMID 7534774 DOI: 10.1002/Cne.903510105 |
0.637 |
|
1994 |
Borsook D, Konradi C, Falkowski O, Comb M, Hyman SE. Molecular mechanisms of stress-induced proenkephalin gene regulation: CREB interacts with the proenkephalin gene in the mouse hypothalamus and is phosphorylated in response to hyperosmolar stress. Molecular Endocrinology (Baltimore, Md.). 8: 240-8. PMID 8170480 DOI: 10.1210/Mend.8.2.8170480 |
0.636 |
|
1994 |
Borsook D, Falkowski O, Burstein R, Strassman A, Konradi C, Dauber A, Comb M, Hyman SE. Stress-induced regulation of a human proenkephalin-beta-galactosidase fusion gene in the hypothalamus of transgenic mice. Molecular Endocrinology (Baltimore, Md.). 8: 116-25. PMID 8152426 DOI: 10.1210/Mend.8.1.8152426 |
0.605 |
|
1994 |
Konradi C, Cole RL, Heckers S, Hyman SE. Amphetamine regulates gene expression in rat striatum via transcription factor CREB. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 5623-34. PMID 8083758 DOI: 10.1523/Jneurosci.14-09-05623.1994 |
0.676 |
|
1994 |
Borsook D, Falkowski O, Rosen H, Comb M, Hyman SE. Opioids modulate stress-induced proenkephalin gene expression in the hypothalamus of transgenic mice: a model of endogenous opioid gene regulation by exogenous opioids. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 7261-71. PMID 7996174 DOI: 10.1016/0167-0115(94)90373-5 |
0.333 |
|
1994 |
Cole DG, Kobierski LA, Konradi C, Hyman SE. 6-Hydroxydopamine lesions of rat substantia nigra up-regulate dopamine-induced phosphorylation of the cAMP-response element-binding protein in striatal neurons. Proceedings of the National Academy of Sciences of the United States of America. 91: 9631-5. PMID 7937819 DOI: 10.1073/Pnas.91.20.9631 |
0.631 |
|
1994 |
Hyman SE, Konradi C, Kobierski L, Cole R, Senatus P, Green D. Pharmacologic regulation of striatal proenkephalin gene expression via transcription factor CREB. Progress in Clinical and Biological Research. 390: 155-71. PMID 7724644 |
0.602 |
|
1994 |
Symes A, Lewis S, Corpus L, Rajan P, Hyman SE, Fink JS. STAT proteins participate in the regulation of the vasoactive intestinal peptide gene by the ciliary neurotrophic factor family of cytokines. Molecular Endocrinology (Baltimore, Md.). 8: 1750-63. PMID 7708062 DOI: 10.1210/Mend.8.12.7708062 |
0.584 |
|
1994 |
Schwarzschild MA, Dauer WT, Lewis SE, Hamill LK, Fink JS, Hyman SE. Leukemia inhibitory factor and ciliary neurotrophic factor increase activated Ras in a neuroblastoma cell line and in sympathetic neuron cultures. Journal of Neurochemistry. 63: 1246-54. PMID 7523587 DOI: 10.1046/J.1471-4159.1994.63041246.X |
0.548 |
|
1994 |
Lewis SE, Rao MS, Symes AJ, Dauer WT, Fink JS, Landis SC, Hyman SE. Coordinate regulation of choline acetyltransferase, tyrosine hydroxylase, and neuropeptide mRNAs by ciliary neurotrophic factor and leukemia inhibitory factor in cultured sympathetic neurons. Journal of Neurochemistry. 63: 429-38. PMID 7518494 DOI: 10.1046/J.1471-4159.1994.63020429.X |
0.561 |
|
1994 |
Hyman SE, Konradi C, Cole RL. Regulation of striatal proenkephalin and prodynorphin gene expression by transcription factor CREB Regulatory Peptides. 54: 127-128. DOI: 10.1016/0167-0115(94)90422-7 |
0.633 |
|
1993 |
Hyman SE. New insights into how antipsychotic drugs might work. Harvard Review of Psychiatry. 1: 68-9. PMID 9384831 DOI: 10.3109/10673229309017060 |
0.305 |
|
1993 |
Konradi C, Kobierski LA, Nguyen TV, Heckers S, Hyman SE. The cAMP-response-element-binding protein interacts, but Fos protein does not interact, with the proenkephalin enhancer in rat striatum. Proceedings of the National Academy of Sciences of the United States of America. 90: 7005-9. PMID 8346209 DOI: 10.1073/Pnas.90.15.7005 |
0.635 |
|
1993 |
Hyman SE, Kosofsky BE, Nguyen TV, Cohen BM, Comb MJ. Everything activates c-fos--how can it matter? Nida Research Monograph. 125: 25-38. PMID 8341366 |
0.597 |
|
1993 |
Kosofsky BE, Hyman SE. The ontogeny of immediate early gene response to cocaine: a molecular analysis of the effects of cocaine on developing rat brain. Nida Research Monograph. 125: 161-71. PMID 8341363 |
0.567 |
|
1993 |
Symes AJ, Rao MS, Lewis SE, Landis SC, Hyman SE, Fink JS. Ciliary neurotrophic factor coordinately activates transcription of neuropeptide genes in a neuroblastoma cell line. Proceedings of the National Academy of Sciences of the United States of America. 90: 572-6. PMID 8093644 DOI: 10.1073/Pnas.90.2.572 |
0.587 |
|
1992 |
Hope B, Kosofsky B, Hyman SE, Nestler EJ. Regulation of immediate early gene expression and AP-1 binding in the rat nucleus accumbens by chronic cocaine. Proceedings of the National Academy of Sciences of the United States of America. 89: 5764-8. PMID 1631058 DOI: 10.1073/Pnas.89.13.5764 |
0.735 |
|
1992 |
Comb MJ, Kobierski L, Chu HM, Tan Y, Borsook D, Herrup K, Hyman SE. Regulation of opioid gene expression: a model to understand neural plasticity. Nida Research Monograph. 126: 98-112. PMID 1491720 |
0.302 |
|
1992 |
Borsook D, Rosen H, Collard M, Dressler H, Herrup K, Comb MJ, Hyman SE. Expression and regulation of a proenkephalin beta-galactosidase fusion gene in the reproductive system of transgenic mice. Molecular Endocrinology (Baltimore, Md.). 6: 1502-12. PMID 1435791 DOI: 10.1210/Mend.6.9.1435791 |
0.31 |
|
1992 |
Nguyen TV, Kosofsky BE, Birnbaum R, Cohen BM, Hyman SE. Differential expression of c-fos and zif268 in rat striatum after haloperidol, clozapine, and amphetamine. Proceedings of the National Academy of Sciences of the United States of America. 89: 4270-4. PMID 1374894 DOI: 10.1073/Pnas.89.10.4270 |
0.645 |
|
1990 |
Ross ME, Evinger MJ, Hyman SE, Carroll JM, Mucke L, Comb M, Reis DJ, Joh TH, Goodman HM. Identification of a functional glucocorticoid response element in the phenylethanolamine N-methyltransferase promoter using fusion genes introduced into chromaffin cells in primary culture. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 520-30. PMID 2303857 DOI: 10.1523/Jneurosci.10-02-00520.1990 |
0.525 |
|
1990 |
Van Nguyen T, Kobierski L, Comb M, Hyman SE. The effect of depolarization on expression of the human proenkephalin gene is synergistic with cAMP and dependent upon a cAMP-inducible enhancer. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 2825-33. PMID 2167356 DOI: 10.1523/Jneurosci.10-08-02825.1990 |
0.355 |
|
1989 |
Hyman SE, Comb M, Pearlberg J, Goodman HM. An AP-2 element acts synergistically with the cyclic AMP- and phorbol ester-inducible enhancer of the human proenkephalin gene. Molecular and Cellular Biology. 9: 321-4. PMID 2538722 DOI: 10.1128/Mcb.9.1.321 |
0.508 |
|
1988 |
Hyman SE, Comb M, Lin YS, Pearlberg J, Green MR, Goodman HM. A common trans-acting factor is involved in transcriptional regulation of neurotransmitter genes by cyclic AMP. Molecular and Cellular Biology. 8: 4225-33. PMID 2903436 DOI: 10.1128/Mcb.8.10.4225 |
0.548 |
|
1988 |
Comb M, Mermod N, Hyman SE, Pearlberg J, Ross ME, Goodman HM. Proteins bound at adjacent DNA elements act synergistically to regulate human proenkephalin cAMP inducible transcription. The Embo Journal. 7: 3793-805. PMID 2850173 DOI: 10.1002/J.1460-2075.1988.Tb03264.X |
0.518 |
|
1988 |
Hyman SE. Recent developments in neurobiology: Part I. Synaptic transmission. Psychosomatics. 29: 157-65. PMID 2453072 DOI: 10.1016/S0033-3182(88)72392-0 |
0.317 |
|
1987 |
Schalling M, Dagerlind A, Brene S, Petterson R, Kvist S, Brownstein M, Hyman SE, Mucke L, Goodman HM, Joh TH. Localization of mRNA for phenylethanolamine N-methyltransferase (PNMT) using in situ hybridization. Acta Physiologica Scandinavica. 131: 631-2. PMID 3442246 DOI: 10.1111/J.1748-1716.1987.Tb08288.X |
0.428 |
|
1987 |
Comb M, Hyman SE, Goodman HM. Mechanisms of trans-synaptic regulation of gene expression Trends in Neurosciences. 10: 473-478. DOI: 10.1016/0166-2236(87)90103-2 |
0.546 |
|
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