Carlos Ibanez - Publications

Affiliations: 
Karolinska Institute, Stockholm, Sweden 
Area:
Neurotrophins
Website:
http://zephyr.neuro.ki.se/

128 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Lin Z, Tann JY, Goh ET, Kelly C, Lim KB, Gao JF, Ibanez CF. Structural basis of death domain signaling in the p75 neurotrophin receptor. Elife. 4. PMID 26646181 DOI: 10.7554/eLife.11692  0.8
2015 Vicario A, Kisiswa L, Tann JY, Kelly CE, Ibáñez CF. Neuron-type-specific signaling by the p75NTR death receptor is regulated by differential proteolytic cleavage. Journal of Cell Science. 128: 1507-17. PMID 25720379 DOI: 10.1242/jcs.161745  0.8
2014 Zechel S, Zajac P, Lönnerberg P, Ibáñez CF, Linnarsson S. Topographical transcriptome mapping of the mouse medial ganglionic eminence by spatially resolved RNA-seq. Genome Biology. 15: 486. PMID 25344199 DOI: 10.1186/s13059-014-0486-z  0.8
2014 Wu H, Mezghenna K, Marmol P, Guo T, Moliner A, Yang SN, Berggren PO, Ibáñez CF. Differential regulation of mouse pancreatic islet insulin secretion and Smad proteins by activin ligands. Diabetologia. 57: 148-56. PMID 24132781 DOI: 10.1007/s00125-013-3079-6  0.76
2013 Ibáñez CF. Structure and physiology of the RET receptor tyrosine kinase. Cold Spring Harbor Perspectives in Biology. 5. PMID 23378586 DOI: 10.1101/cshperspect.a009134  0.76
2012 Charalampopoulos I, Vicario A, Pediaditakis I, Gravanis A, Simi A, Ibáñez CF. Genetic dissection of neurotrophin signaling through the p75 neurotrophin receptor. Cell Reports. 2: 1563-70. PMID 23260665 DOI: 10.1016/j.celrep.2012.11.009  0.76
2012 Marks C, Belluscio L, Ibáñez CF. Critical role of GFRα1 in the development and function of the main olfactory system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 17306-20. PMID 23197722 DOI: 10.1523/JNEUROSCI.1522-12.2012  0.8
2012 Sandoval-Guzmán T, Göngrich C, Moliner A, Guo T, Wu H, Broberger C, Ibáñez CF. Neuroendocrine control of female reproductive function by the activin receptor ALK7. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 4966-76. PMID 22954591 DOI: 10.1096/fj.11-199059  0.8
2012 Ibáñez CF, Simi A. p75 neurotrophin receptor signaling in nervous system injury and degeneration: paradox and opportunity. Trends in Neurosciences. 35: 431-40. PMID 22503537 DOI: 10.1016/j.tins.2012.03.007  0.76
2010 Perrinjaquet M, Vilar M, Ibáñez CF. Protein-tyrosine phosphatase SHP2 contributes to GDNF neurotrophic activity through direct binding to phospho-Tyr687 in the RET receptor tyrosine kinase. The Journal of Biological Chemistry. 285: 31867-75. PMID 20682772 DOI: 10.1074/jbc.M110.144923  0.76
2010 Ibáñez CF. Beyond the cell surface: new mechanisms of receptor function. Biochemical and Biophysical Research Communications. 396: 24-7. PMID 20494105 DOI: 10.1016/j.bbrc.2010.01.136  0.76
2010 Simi A, Ibáñez CF. Assembly and activation of neurotrophic factor receptor complexes. Developmental Neurobiology. 70: 323-31. PMID 20186713 DOI: 10.1002/dneu.20773  0.76
2009 Canty AJ, Dietze J, Harvey M, Enomoto H, Milbrandt J, Ibáñez CF. Regionalized loss of parvalbumin interneurons in the cerebral cortex of mice with deficits in GFRalpha1 signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 10695-705. PMID 19710321 DOI: 10.1523/JNEUROSCI.2658-09.2009  0.36
2009 Vilar M, Charalampopoulos I, Kenchappa RS, Reversi A, Klos-Applequist JM, Karaca E, Simi A, Spuch C, Choi S, Friedman WJ, Ericson J, Schiavo G, Carter BD, Ibáñez CF. Ligand-independent signaling by disulfide-crosslinked dimers of the p75 neurotrophin receptor. Journal of Cell Science. 122: 3351-7. PMID 19706676 DOI: 10.1242/jcs.055061  0.36
2009 Vilar M, Charalampopoulos I, Kenchappa RS, Simi A, Karaca E, Reversi A, Choi S, Bothwell M, Mingarro I, Friedman WJ, Schiavo G, Bastiaens PI, Verveer PJ, Carter BD, Ibáñez CF. Activation of the p75 neurotrophin receptor through conformational rearrangement of disulphide-linked receptor dimers. Neuron. 62: 72-83. PMID 19376068 DOI: 10.1016/j.neuron.2009.02.020  0.36
2008 Ibanez CF, Häusser M. Signalling mechanisms. Current Opinion in Neurobiology. 18: 229-31. PMID 19180740 DOI: 10.1016/j.conb.2008.09.011  0.36
2008 Ibáñez CF. Catecholaminergic neuron survival: getting hooked on GDNF. Nature Neuroscience. 11: 735-6. PMID 18575468 DOI: 10.1038/nn0708-735  0.76
2008 Andäng M, Moliner A, Doege CA, Ibañez CF, Ernfors P. Optimized mouse ES cell culture system by suspension growth in a fully defined medium. Nature Protocols. 3: 1013-7. PMID 18536648 DOI: 10.1038/nprot.2008.65  0.8
2008 Andersson O, Korach-Andre M, Reissmann E, Ibáñez CF, Bertolino P. Growth/differentiation factor 3 signals through ALK7 and regulates accumulation of adipose tissue and diet-induced obesity. Proceedings of the National Academy of Sciences of the United States of America. 105: 7252-6. PMID 18480259 DOI: 10.1073/pnas.0800272105  0.76
2008 Bertolino P, Holmberg R, Reissmann E, Andersson O, Berggren PO, Ibáñez CF. Activin B receptor ALK7 is a negative regulator of pancreatic beta-cell function. Proceedings of the National Academy of Sciences of the United States of America. 105: 7246-51. PMID 18480258 DOI: 10.1073/pnas.0801285105  0.76
2008 Moliner A, Enfors P, Ibáñez CF, Andäng M. Mouse embryonic stem cell-derived spheres with distinct neurogenic potentials. Stem Cells and Development. 17: 233-43. PMID 18447639 DOI: 10.1089/scd.2007.0211  0.76
2008 Sjöstrand D, Ibáñez CF. Insights into GFRalpha1 regulation of neural cell adhesion molecule (NCAM) function from structure-function analysis of the NCAM/GFRalpha1 receptor complex. The Journal of Biological Chemistry. 283: 13792-8. PMID 18353777 DOI: 10.1074/jbc.M800283200  0.76
2008 Andäng M, Hjerling-Leffler J, Moliner A, Lundgren TK, Castelo-Branco G, Nanou E, Pozas E, Bryja V, Halliez S, Nishimaru H, Wilbertz J, Arenas E, Koltzenburg M, Charnay P, El Manira A, et al. Histone H2AX-dependent GABA(A) receptor regulation of stem cell proliferation. Nature. 451: 460-4. PMID 18185516 DOI: 10.1038/nature06488  0.8
2007 Ibáñez CF. Message in a bottle: long-range retrograde signaling in the nervous system. Trends in Cell Biology. 17: 519-28. PMID 18029183 DOI: 10.1016/j.tcb.2007.09.003  0.76
2007 Andersson O, Bertolino P, Ibáñez CF. Distinct and cooperative roles of mammalian Vg1 homologs GDF1 and GDF3 during early embryonic development. Developmental Biology. 311: 500-11. PMID 17936261 DOI: 10.1016/j.ydbio.2007.08.060  0.76
2007 Ibáñez CF, Ernfors P. Hierarchical control of sensory neuron development by neurotrophic factors. Neuron. 54: 673-5. PMID 17553418 DOI: 10.1016/j.neuron.2007.05.023  0.8
2007 Sjöstrand D, Carlsson J, Paratcha G, Persson B, Ibáñez CF. Disruption of the GDNF binding site in NCAM dissociates ligand binding and homophilic cell adhesion. The Journal of Biological Chemistry. 282: 12734-40. PMID 17322291 DOI: 10.1074/jbc.M701588200  0.8
2007 Ledda F, Paratcha G, Sandoval-Guzmán T, Ibáñez CF. GDNF and GFRalpha1 promote formation of neuronal synapses by ligand-induced cell adhesion. Nature Neuroscience. 10: 293-300. PMID 17310246 DOI: 10.1038/nn1855  0.76
2006 Knowles PP, Murray-Rust J, Kjaer S, Scott RP, Hanrahan S, Santoro M, Ibáñez CF, McDonald NQ. Structure and chemical inhibition of the RET tyrosine kinase domain. The Journal of Biological Chemistry. 281: 33577-87. PMID 16928683 DOI: 10.1074/jbc.M605604200  0.8
2006 Andersson O, Reissmann E, Ibáñez CF. Growth differentiation factor 11 signals through the transforming growth factor-beta receptor ALK5 to regionalize the anterior-posterior axis. Embo Reports. 7: 831-7. PMID 16845371 DOI: 10.1038/sj.embor.7400752  0.76
2006 Kjaer S, Kurokawa K, Perrinjaquet M, Abrescia C, Ibáñez CF. Self-association of the transmembrane domain of RET underlies oncogenic activation by MEN2A mutations. Oncogene. 25: 7086-95. PMID 16732321 DOI: 10.1038/sj.onc.1209698  0.76
2006 Andersson O, Reissmann E, Jörnvall H, Ibáñez CF. Synergistic interaction between Gdf1 and Nodal during anterior axis development. Developmental Biology. 293: 370-81. PMID 16564040 DOI: 10.1016/j.ydbio.2006.02.002  0.76
2006 Vilar M, Murillo-Carretero M, Mira H, Magnusson K, Besset V, Ibáñez CF. Bex1, a novel interactor of the p75 neurotrophin receptor, links neurotrophin signaling to the cell cycle. The Embo Journal. 25: 1219-30. PMID 16498402 DOI: 10.1038/sj.emboj.7601017  0.76
2006 Paratcha G, Ibáñez CF, Ledda F. GDNF is a chemoattractant factor for neuronal precursor cells in the rostral migratory stream. Molecular and Cellular Neurosciences. 31: 505-14. PMID 16380265 DOI: 10.1016/j.mcn.2005.11.007  0.8
2006 Alcántara S, Pozas E, Ibañez CF, Soriano E. BDNF-modulated spatial organization of Cajal-Retzius and GABAergic neurons in the marginal zone plays a role in the development of cortical organization. Cerebral Cortex (New York, N.Y. : 1991). 16: 487-99. PMID 16000651 DOI: 10.1093/cercor/bhi128  0.8
2005 Martínez A, Otal R, Sieber BA, Ibáñez C, Soriano E. Disruption of ephrin-A/EphA binding alters synaptogenesis and neural connectivity in the hippocampus. Neuroscience. 135: 451-61. PMID 16112477 DOI: 10.1016/j.neuroscience.2005.06.052  0.8
2005 Abrescia C, Sjöstrand D, Kjaer S, Ibáñez CF. Drosophila RET contains an active tyrosine kinase and elicits neurotrophic activities in mammalian cells. Febs Letters. 579: 3789-96. PMID 15978587 DOI: 10.1016/j.febslet.2005.05.075  0.76
2005 Pozas E, Ibáñez CF. GDNF and GFRalpha1 promote differentiation and tangential migration of cortical GABAergic neurons. Neuron. 45: 701-13. PMID 15748846 DOI: 10.1016/j.neuron.2005.01.043  0.76
2005 Scott RP, Eketjäll S, Aineskog H, Ibáñez CF. Distinct turnover of alternatively spliced isoforms of the RET kinase receptor mediated by differential recruitment of the Cbl ubiquitin ligase. The Journal of Biological Chemistry. 280: 13442-9. PMID 15677445 DOI: 10.1074/jbc.M500507200  0.76
2004 Jörnvall H, Reissmann E, Andersson O, Mehrkash M, Ibáñez CF. ALK7, a receptor for nodal, is dispensable for embryogenesis and left-right patterning in the mouse. Molecular and Cellular Biology. 24: 9383-9. PMID 15485907 DOI: 10.1128/MCB.24.21.9383-9389.2004  0.76
2004 Coulpier M, Ibáñez CF. Retrograde propagation of GDNF-mediated signals in sympathetic neurons. Molecular and Cellular Neurosciences. 27: 132-9. PMID 15485769 DOI: 10.1016/j.mcn.2004.06.001  0.76
2004 Sieber BA, Kuzmin A, Canals JM, Danielsson A, Paratcha G, Arenas E, Alberch J, Ogren SO, Ibáñez CF. Disruption of EphA/ephrin-a signaling in the nigrostriatal system reduces dopaminergic innervation and dissociates behavioral responses to amphetamine and cocaine. Molecular and Cellular Neurosciences. 26: 418-28. PMID 15234346 DOI: 10.1016/j.mcn.2004.03.009  0.8
2004 Ibáñez CF. Lipid rafts as organizing platforms for cell chemotaxis and axon guidance. Neuron. 42: 3-5. PMID 15066259  0.76
2004 Eketjäll S, Jörnvall H, Lönnerberg P, Kobayashi S, Ibáñez CF. Recent evolutionary origin within the primate lineage of two pseudogenes with similarity to members of the transforming growth factor-beta superfamily. Cellular and Molecular Life Sciences : Cmls. 61: 488-96. PMID 14999407 DOI: 10.1007/s00018-003-3383-2  0.76
2004 Ibanez CF. Framework reveals lack of basic-research funds. Nature. 427: 485. PMID 14765168 DOI: 10.1038/427485b  0.8
2003 Blokzijl A, Dahlqvist C, Reissmann E, Falk A, Moliner A, Lendahl U, Ibáñez CF. Cross-talk between the Notch and TGF-beta signaling pathways mediated by interaction of the Notch intracellular domain with Smad3. The Journal of Cell Biology. 163: 723-8. PMID 14638857 DOI: 10.1083/jcb.200305112  0.76
2003 Dahlqvist C, Blokzijl A, Chapman G, Falk A, Dannaeus K, Ibâñez CF, Lendahl U. Functional Notch signaling is required for BMP4-induced inhibition of myogenic differentiation. Development (Cambridge, England). 130: 6089-99. PMID 14597575 DOI: 10.1242/dev.00834  0.52
2003 Kjaer S, Ibáñez CF. Identification of a surface for binding to the GDNF-GFR alpha 1 complex in the first cadherin-like domain of RET. The Journal of Biological Chemistry. 278: 47898-904. PMID 14514671 DOI: 10.1074/jbc.M309772200  0.76
2003 Kjaer S, Ibáñez CF. Intrinsic susceptibility to misfolding of a hot-spot for Hirschsprung disease mutations in the ectodomain of RET. Human Molecular Genetics. 12: 2133-44. PMID 12915470 DOI: 10.1093/hmg/ddg227  0.76
2003 Paratcha G, Ledda F, Ibáñez CF. The neural cell adhesion molecule NCAM is an alternative signaling receptor for GDNF family ligands. Cell. 113: 867-79. PMID 12837245 DOI: 10.1016/S0092-8674(03)00435-5  0.8
2003 Aguado F, Carmona MA, Pozas E, Aguiló A, Martínez-Guijarro FJ, Alcantara S, Borrell V, Yuste R, Ibañez CF, Soriano E. BDNF regulates spontaneous correlated activity at early developmental stages by increasing synaptogenesis and expression of the K+/Cl- co-transporter KCC2. Development (Cambridge, England). 130: 1267-80. PMID 12588844 DOI: 10.1242/dev.00351  0.8
2002 Ledda F, Paratcha G, Ibáñez CF. Target-derived GFRalpha1 as an attractive guidance signal for developing sensory and sympathetic axons via activation of Cdk5. Neuron. 36: 387-401. PMID 12408843 DOI: 10.1016/S0896-6273(02)01002-4  0.8
2002 Paratcha G, Ibáñez CF. Lipid rafts and the control of neurotrophic factor signaling in the nervous system: variations on a theme. Current Opinion in Neurobiology. 12: 542-9. PMID 12367633 DOI: 10.1016/S0959-4388(02)00363-X  0.76
2002 Ibáñez CF. Jekyll-Hyde neurotrophins: the story of proNGF. Trends in Neurosciences. 25: 284-6. PMID 12086739  0.76
2002 Eketjäll S, Ibáñez CF. Functional characterization of mutations in the GDNF gene of patients with Hirschsprung disease. Human Molecular Genetics. 11: 325-9. PMID 11823451  0.76
2002 Blokzijl A, ten Dijke P, Ibáñez CF. Physical and functional interaction between GATA-3 and Smad3 allows TGF-beta regulation of GATA target genes. Current Biology : Cb. 12: 35-45. PMID 11790301  0.76
2002 Coulpier M, Anders J, Ibáñez CF. Coordinated activation of autophosphorylation sites in the RET receptor tyrosine kinase: importance of tyrosine 1062 for GDNF mediated neuronal differentiation and survival. The Journal of Biological Chemistry. 277: 1991-9. PMID 11713247 DOI: 10.1074/jbc.M107992200  0.76
2001 Reissmann E, Jörnvall H, Blokzijl A, Andersson O, Chang C, Minchiotti G, Persico MG, Ibáñez CF, Brivanlou AH. The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development. Genes & Development. 15: 2010-22. PMID 11485994 DOI: 10.1101/gad.201801  0.8
2001 Belluardo N, Westerblad H, Mudó G, Casabona A, Bruton J, Caniglia G, Pastoris O, Grassi F, Ibáñez CF. Neuromuscular junction disassembly and muscle fatigue in mice lacking neurotrophin-4. Molecular and Cellular Neurosciences. 18: 56-67. PMID 11461153 DOI: 10.1006/mcne.2001.1001  0.8
2001 Anders J, Kjar S, Ibáñez CF. Molecular modeling of the extracellular domain of the RET receptor tyrosine kinase reveals multiple cadherin-like domains and a calcium-binding site. The Journal of Biological Chemistry. 276: 35808-17. PMID 11445581 DOI: 10.1074/jbc.M104968200  0.76
2001 De Wilde G, Murray-Rust J, Boone E, Olerenshaw D, McDonald NQ, Ibanez C, Haegeman G, Wollmer A, Federwisch M. Structure-activity relationship of the p55 TNF receptor death domain and its lymphoproliferation mutants. European Journal of Biochemistry / Febs. 268: 1382-91. PMID 11231290 DOI: 10.1046/j.1432-1327.2001.02004.x  0.8
2001 Paratcha G, Ledda F, Baars L, Coulpier M, Besset V, Anders J, Scott R, Ibáñez CF. Released GFRalpha1 potentiates downstream signaling, neuronal survival, and differentiation via a novel mechanism of recruitment of c-Ret to lipid rafts. Neuron. 29: 171-84. PMID 11182089 DOI: 10.1016/S0896-6273(01)00188-X  0.8
2001 Jörnvall H, Blokzijl A, ten Dijke P, Ibáñez CF. The orphan receptor serine/threonine kinase ALK7 signals arrest of proliferation and morphological differentiation in a neuronal cell line. The Journal of Biological Chemistry. 276: 5140-6. PMID 11084022 DOI: 10.1074/jbc.M005200200  0.76
2000 Donovan MJ, Lin MI, Wiegn P, Ringstedt T, Kraemer R, Hahn R, Wang S, Ibañez CF, Rafii S, Hempstead BL. Brain derived neurotrophic factor is an endothelial cell survival factor required for intramyocardial vessel stabilization. Development (Cambridge, England). 127: 4531-40. PMID 11023857  0.8
2000 Besset V, Scott RP, Ibáñez CF. Signaling complexes and protein-protein interactions involved in the activation of the Ras and phosphatidylinositol 3-kinase pathways by the c-Ret receptor tyrosine kinase. The Journal of Biological Chemistry. 275: 39159-66. PMID 10995764 DOI: 10.1074/jbc.M006908200  0.76
2000 Masure S, Cik M, Hoefnagel E, Nosrat CA, Van der Linden I, Scott R, Van Gompel P, Lesage AS, Verhasselt P, Ibáñez CF, Gordon RD. Mammalian GFRalpha -4, a divergent member of the GFRalpha family of coreceptors for glial cell line-derived neurotrophic factor family ligands, is a receptor for the neurotrophic factor persephin. The Journal of Biological Chemistry. 275: 39427-34. PMID 10958791 DOI: 10.1074/jbc.M003867200  0.8
2000 Ibáñez CF. Neurotrophic factors: versatile signals for cell-cell communication in the nervous system. Results and Problems in Cell Differentiation. 30: 163-88. PMID 10857189  0.76
1999 Eketjäll S, Fainzilber M, Murray-Rust J, Ibáñez CF. Distinct structural elements in GDNF mediate binding to GFRalpha1 and activation of the GFRalpha1-c-Ret receptor complex. The Embo Journal. 18: 5901-10. PMID 10545102 DOI: 10.1093/emboj/18.21.5901  0.8
1999 Trupp M, Scott R, Whittemore SR, Ibáñez CF. Ret-dependent and -independent mechanisms of glial cell line-derived neurotrophic factor signaling in neuronal cells. The Journal of Biological Chemistry. 274: 20885-94. PMID 10409632 DOI: 10.1074/jbc.274.30.20885  0.8
1999 Shafqat J, Höög JO, Hjelmqvist L, Oppermann UC, Ibáñez C, Jörnvall H. An ethanol-inducible MDR ethanol dehydrogenase/acetaldehyde reductase in Escherichia coli: structural and enzymatic relationships to the eukaryotic protein forms. European Journal of Biochemistry / Febs. 263: 305-11. PMID 10406936  0.32
1999 Lönnerberg P, Ibáñez CF. Novel, testis-specific mRNA transcripts encoding N-terminally truncated choline acetyltransferase. Molecular Reproduction and Development. 53: 274-81. PMID 10369388 DOI: 10.1002/(SICI)1098-2795(199907)53:3<274::AID-MRD3>3.0.CO;2-8  0.76
1999 Shafqat J, Höög JO, Hjelmqvist L, Oppermann U, Ibanez C, Jörnvall H. Studies on variants of alcohol dehydrogenases and its domains. Advances in Experimental Medicine and Biology. 463: 285-93. PMID 10352697  0.8
1999 Ringstedt T, Ibáñez CF, Nosrat CA. Role of brain-derived neurotrophic factor in target invasion in the gustatory system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 3507-18. PMID 10212310  0.76
1999 Ibáñez CF. Researchers face 'Catch-22' grants trap. Nature. 398: 280. PMID 10192324 DOI: 10.1038/18536  0.76
1998 Ibáñez CF. Emerging themes in structural biology of neurotrophic factors. Trends in Neurosciences. 21: 438-44. PMID 9786342  0.76
1998 Ringstedt T, Linnarsson S, Wagner J, Lendahl U, Kokaia Z, Arenas E, Ernfors P, Ibáñez CF. BDNF regulates reelin expression and Cajal-Retzius cell development in the cerebral cortex. Neuron. 21: 305-15. PMID 9728912  0.8
1998 Trupp M, Raynoschek C, Belluardo N, Ibáñez CF. Multiple GPI-anchored receptors control GDNF-dependent and independent activation of the c-Ret receptor tyrosine kinase. Molecular and Cellular Neurosciences. 11: 47-63. PMID 9608533 DOI: 10.1006/mcne.1998.0667  0.76
1998 Nilsson AS, Fainzilber M, Falck P, Ibáñez CF. Neurotrophin-7: a novel member of the neurotrophin family from the zebrafish. Febs Letters. 424: 285-90. PMID 9580190 DOI: 10.1016/S0014-5793(98)00192-6  0.8
1998 van Kesteren RE, Fainzilber M, Hauser G, van Minnen J, Vreugdenhil E, Smit AB, Ibáñez CF, Geraerts WP, Bulloch AG. Early evolutionary origin of the neurotrophin receptor family. The Embo Journal. 17: 2534-42. PMID 9564036 DOI: 10.1093/emboj/17.9.2534  0.76
1998 Funakoshi H, Risling M, Carlstedt T, Lendahl U, Timmusk T, Metsis M, Yamamoto Y, Ibáñez CF. Targeted expression of a multifunctional chimeric neurotrophin in the lesioned sciatic nerve accelerates regeneration of sensory and motor axons. Proceedings of the National Academy of Sciences of the United States of America. 95: 5269-74. PMID 9560265  0.76
1997 Svensson T, Rydén M, Schilling FH, Dominici C, Sehgal R, Ibáñez CF, Kogner P. Coexpression of mRNA for the full-length neurotrophin receptor trk-C and trk-A in favourable neuroblastoma. European Journal of Cancer (Oxford, England : 1990). 33: 2058-63. PMID 9580079  0.76
1997 Rydén M, Ibáñez CF. A second determinant of binding to the p75 neurotrophin receptor revealed by alanine-scanning mutagenesis of a conserved loop in nerve growth factor. The Journal of Biological Chemistry. 272: 33085-91. PMID 9407092  0.76
1997 Liepinsh E, Ilag LL, Otting G, Ibáñez CF. NMR structure of the death domain of the p75 neurotrophin receptor. The Embo Journal. 16: 4999-5005. PMID 9305641 DOI: 10.1093/emboj/16.16.4999  0.76
1997 Ringstedt T, Kucera J, Lendahl U, Ernfors P, Ibáñez CF. Limb proprioceptive deficits without neuronal loss in transgenic mice overexpressing neurotrophin-3 in the developing nervous system. Development (Cambridge, England). 124: 2603-13. PMID 9217002  0.8
1997 Rydén M, Hempstead B, Ibáñez CF. Differential modulation of neuron survival during development by nerve growth factor binding to the p75 neurotrophin receptor. The Journal of Biological Chemistry. 272: 16322-8. PMID 9195937  0.76
1997 Trupp M, Belluardo N, Funakoshi H, Ibáñez CF. Complementary and overlapping expression of glial cell line-derived neurotrophic factor (GDNF), c-ret proto-oncogene, and GDNF receptor-alpha indicates multiple mechanisms of trophic actions in the adult rat CNS. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 3554-67. PMID 9133379  0.76
1997 Kontny E, Ciruela F, Svenningsson P, Ibáñez CF, Fredholm BB. On the role of the low-affinity neurotrophin receptor p75LNTR in nerve growth factor induction of differentiation and AP 1 binding activity in PC12 cells. Journal of Molecular Neuroscience : Mn. 8: 29-44. PMID 9061613 DOI: 10.1007/BF02736861  0.8
1996 Lönnerberg P, Schoenherr CJ, Anderson DJ, Ibáñez CF. Cell type-specific regulation of choline acetyltransferase gene expression. Role of the neuron-restrictive silencer element and cholinergic-specific enhancer sequences. The Journal of Biological Chemistry. 271: 33358-65. PMID 8969196 DOI: 10.1074/jbc.271.52.33358  0.8
1996 Bürgi B, Otten UH, Ochensberger B, Rihs S, Heese K, Ehrhard PB, Ibanez CF, Dahinden CA. Basophil priming by neurotrophic factors. Activation through the trk receptor. Journal of Immunology (Baltimore, Md. : 1950). 157: 5582-8. PMID 8955210  0.8
1996 Rydén M, Imamura T, Jörnvall H, Belluardo N, Neveu I, Trupp M, Okadome T, ten Dijke P, Ibáñez CF. A novel type I receptor serine-threonine kinase predominantly expressed in the adult central nervous system. The Journal of Biological Chemistry. 271: 30603-9. PMID 8940033  0.76
1996 Fainzilber M, Smit AB, Syed NI, Wildering WC, Hermann, van der Schors RC, Jiménez C, Li KW, van Minnen J, Bulloch AG, Ibáñez CF, Geraerts WP. CRNF, a molluscan neurotrophic factor that interacts with the p75 neurotrophin receptor. Science (New York, N.Y.). 274: 1540-3. PMID 8929417 DOI: 10.1126/science.274.5292.1540  0.8
1996 Ibáñez CF. Neurotrophin-4: the odd one out in the neurotrophin family. Neurochemical Research. 21: 787-93. PMID 8873083  0.76
1996 Rydén M, Sehgal R, Dominici C, Schilling FH, Ibáñez CF, Kogner P. Expression of mRNA for the neurotrophin receptor trkC in neuroblastomas with favourable tumour stage and good prognosis. British Journal of Cancer. 74: 773-9. PMID 8795581  0.76
1996 Trupp M, Arenas E, Fainzilber M, Nilsson AS, Sieber BA, Grigoriou M, Kilkenny C, Salazar-Grueso E, Pachnis V, Arumäe U. Functional receptor for GDNF encoded by the c-ret proto-oncogene. Nature. 381: 785-9. PMID 8657281 DOI: 10.1038/381785a0  0.8
1996 Rydén M, Ibáñez CF. Binding of neurotrophin-3 to p75LNGFR, TrkA, and TrkB mediated by a single functional epitope distinct from that recognized by trkC. The Journal of Biological Chemistry. 271: 5623-7. PMID 8621424  0.76
1995 Arenas E, Trupp M, Akerud P, Ibáñez CF. GDNF prevents degeneration and promotes the phenotype of brain noradrenergic neurons in vivo. Neuron. 15: 1465-73. PMID 8845169 DOI: 10.1016/0896-6273(95)90024-1  0.36
1995 Trupp M, Rydén M, Jörnvall H, Funakoshi H, Timmusk T, Arenas E, Ibáñez CF. Peripheral expression and biological activities of GDNF, a new neurotrophic factor for avian and mammalian peripheral neurons. The Journal of Cell Biology. 130: 137-48. PMID 7790368  0.76
1995 Ibáñez CF, Rydén M. [Nerve growth factors in future therapies. Protein mutation broadens the range of therapeutic possibilities]. LäKartidningen. 92: 2191-4. PMID 7776754  0.76
1995 Funakoshi H, Belluardo N, Arenas E, Yamamoto Y, Casabona A, Persson H, Ibáñez CF. Muscle-derived neurotrophin-4 as an activity-dependent trophic signal for adult motor neurons. Science (New York, N.Y.). 268: 1495-9. PMID 7770776  0.8
1995 Rydén M, Murray-Rust J, Glass D, Ilag LL, Trupp M, Yancopoulos GD, McDonald NQ, Ibáñez CF. Functional analysis of mutant neurotrophins deficient in low-affinity binding reveals a role for p75LNGFR in NT-4 signalling. The Embo Journal. 14: 1979-90. PMID 7744005  0.76
1995 Lönnerberg P, Lendahl U, Funakoshi H, Arhlund-Richter L, Persson H, Ibáñez CF. Regulatory region in choline acetyltransferase gene directs developmental and tissue-specific expression in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 92: 4046-50. PMID 7732028  0.8
1995 Friedman WJ, Black IB, Persson H, Ibáñez CF. Synergistic trophic actions on rat basal forebrain neurons revealed by a synthetic NGF/BDNF chimaeric molecule. The European Journal of Neuroscience. 7: 656-62. PMID 7620616  0.8
1995 Ibáñez CF. Neurotrophic factors: from structure-function studies to designing effective therapeutics. Trends in Biotechnology. 13: 217-27. PMID 7598845 DOI: 10.1016/S0167-7799(00)88949-0  0.76
1994 Ilag LL, Lönnerberg P, Persson H, Ibáñez CF. Role of variable beta-hairpin loop in determining biological specificities in neurotrophin family. The Journal of Biological Chemistry. 269: 19941-6. PMID 8051078  0.8
1994 Ibáñez CF. Structure-function relationships in the neurotrophin family. Journal of Neurobiology. 25: 1349-61. PMID 7852990 DOI: 10.1002/neu.480251104  0.8
1994 Bradshaw RA, Murray-Rust J, Ibáñez CF, McDonald NQ, Lapatto R, Blundell TL. Nerve growth factor: structure/function relationships. Protein Science : a Publication of the Protein Society. 3: 1901-13. PMID 7703837 DOI: 10.1002/pro.5560031102  0.8
1994 Verdi JM, Birren SJ, Ibáñez CF, Persson H, Kaplan DR, Benedetti M, Chao MV, Anderson DJ. p75LNGFR regulates Trk signal transduction and NGF-induced neuronal differentiation in MAH cells. Neuron. 12: 733-45. PMID 7512816 DOI: 10.1016/0896-6273(94)90327-1  0.8
1993 Ibáñez CF, Persson H. The nerve growth factor family of neurotrophic factors. Restorative Neurology and Neuroscience. 5: 30-1. PMID 21551686 DOI: 10.3233/RNN-1993-5107  0.8
1993 Ibáñez CF, Ilag LL, Murray-Rust J, Persson H. An extended surface of binding to Trk tyrosine kinase receptors in NGF and BDNF allows the engineering of a multifunctional pan-neurotrophin. The Embo Journal. 12: 2281-93. PMID 8508763  0.8
1993 Friedman WJ, Ibáñez CF, Hallböök F, Persson H, Cain LD, Dreyfus CF, Black IB. Differential actions of neurotrophins in the locus coeruleus and basal forebrain. Experimental Neurology. 119: 72-8. PMID 8432352 DOI: 10.1006/exnr.1993.1007  0.8
1993 Persson H, Ibáñez CF. Role and expression of neurotrophins and the trk family of tyrosine kinase receptors in neural growth and rescue after injury. Current Opinion in Neurology and Neurosurgery. 6: 11-8. PMID 8428057  0.8
1993 Ibáñez CF, Ernfors P, Timmusk T, Ip NY, Arenas E, Yancopoulos GD, Persson H. Neurotrophin-4 is a target-derived neurotrophic factor for neurons of the trigeminal ganglion. Development (Cambridge, England). 117: 1345-53. PMID 8404536  0.8
1993 Hallböök F, Ibáñez CF, Ebendal T, Persson H. Cellular localization of brain-derived neurotrophic factor and neurotrophin-3 mRNA expression in the early chicken embryo. The European Journal of Neuroscience. 5: 1-14. PMID 8074744  0.8
1992 Ibáñez CF, Hallböök F, Godeau F, Persson H. Expression of neurotrophin-4 mRNA during oogenesis in Xenopus laevis. The International Journal of Developmental Biology. 36: 239-45. PMID 1525011  0.8
1992 Ibáñez CF, Ebendal T, Barbany G, Murray-Rust J, Blundell TL, Persson H. Disruption of the low affinity receptor-binding site in NGF allows neuronal survival and differentiation by binding to the trk gene product. Cell. 69: 329-41. PMID 1314703 DOI: 10.1016/0092-8674(92)90413-7  0.8
1992 Ip NY, Ibáñez CF, Nye SH, McClain J, Jones PF, Gies DR, Belluscio L, Le Beau MM, Espinosa R, Squinto SP. Mammalian neurotrophin-4: structure, chromosomal localization, tissue distribution, and receptor specificity. Proceedings of the National Academy of Sciences of the United States of America. 89: 3060-4. PMID 1313578  0.8
1991 Ibáñez CF, Persson H. Localization of Sequences Determining Cell Type Specificity and NGF Responsiveness in the Promoter Region of the Rat Choline Acetyltransferase Gene. The European Journal of Neuroscience. 3: 1309-1315. PMID 12106228  0.8
1991 Ibáñez CF, Ebendal T, Persson H. Chimeric molecules with multiple neurotrophic activities reveal structural elements determining the specificities of NGF and BDNF. The Embo Journal. 10: 2105-10. PMID 2065656  0.8
1991 Hallböök F, Ibáñez CF, Persson H. Evolutionary studies of the nerve growth factor family reveal a novel member abundantly expressed in Xenopus ovary. Neuron. 6: 845-58. PMID 2025430  0.76
1991 Ibáñez CF, Pelto-Huikko M, Söder O, Ritzèn EM, Hersh LB, Hökfelt T, Persson H. Expression of choline acetyltransferase mRNA in spermatogenic cells results in an accumulation of the enzyme in the postacrosomal region of mature spermatozoa. Proceedings of the National Academy of Sciences of the United States of America. 88: 3676-80. PMID 2023918  0.8
1991 Ibáñez CF, Ernfors P, Persson H. Developmental and regional expression of choline acetyltransferase mRNA in the rat central nervous system. Journal of Neuroscience Research. 29: 163-71. PMID 1890697 DOI: 10.1002/jnr.490290205  0.8
1991 Ibáñez CF, Hallböök F, Söderström S, Ebendal T, Persson H. Biological and immunological properties of recombinant human, rat, and chicken nerve growth factors: a comparative study. Journal of Neurochemistry. 57: 1033-41. PMID 1861142  0.8
1991 Ebendal T, Söderström S, Hallböök F, Ernfors P, Ibáñez CF, Persson H, Wetmore C, Strömberg I, Olson L. Human nerve growth factor: biological and immunological activities, and clinical possibilities in neurodegenerative disease. Advances in Experimental Medicine and Biology. 296: 207-25. PMID 1781327  0.8
1990 Ibáñez CF, Hallböök F, Ebendal T, Persson H. Structure-function studies of nerve growth factor: functional importance of highly conserved amino acid residues. The Embo Journal. 9: 1477-83. PMID 2328722  0.76
1990 Ernfors P, Ibáñez CF, Ebendal T, Olson L, Persson H. Molecular cloning and neurotrophic activities of a protein with structural similarities to nerve growth factor: developmental and topographical expression in the brain. Proceedings of the National Academy of Sciences of the United States of America. 87: 5454-8. PMID 2164684  0.8
1990 Söderström S, Hallböök F, Ibáñez CF, Persson H, Ebendal T. Recombinant human beta-nerve growth factor (NGF): biological activity and properties in an enzyme immunoassay. Journal of Neuroscience Research. 27: 665-77. PMID 2079723 DOI: 10.1002/jnr.490270427  0.76
1989 Affranchino JL, Ibañez CF, Luquetti AO, Rassi A, Reyes MB, Macina RA, Aslund L, Pettersson U, Frasch AC. Identification of a Trypanosoma cruzi antigen that is shed during the acute phase of Chagas' disease. Molecular and Biochemical Parasitology. 34: 221-8. PMID 2499788 DOI: 10.1016/0166-6851(89)90050-9  0.36
1988 Ibañez CF, Affranchino JL, Macina RA, Reyes MB, Leguizamon S, Camargo ME, Aslund L, Pettersson U, Frasch AC. Multiple Trypanosoma cruzi antigens containing tandemly repeated amino acid sequence motifs. Molecular and Biochemical Parasitology. 30: 27-33. PMID 3135494 DOI: 10.1016/0166-6851(88)90129-6  0.36
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