Anjali Rajadhyaksha - Publications

Affiliations: 
Weill Cornell Medical College, New York, NY, United States 
Area:
Ca2+, dopamine, drug abuse
Website:
http://www.med.cornell.edu/research/arajadhyaksha/

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Bavley CC, Rice RC, Fischer DK, Fakira AK, Byrne M, Kosovsky M, Rizzo BK, Del Prete D, Alaedini A, Morón JA, Higgins JJ, D'Adamio L, Rajadhyaksha AM. Rescue of learning and memory deficits in the human non-syndromic intellectual disability cereblon knockout mouse model by targeting the AMPK-mTORC1 translational pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29459374 DOI: 10.1523/JNEUROSCI.0599-17.2018  0.52
2018 Na ES, De Jesús-Cortés H, Martinez-Rivera A, Kabir ZD, Wang J, Ramesh V, Onder Y, Rajadhyaksha AM, Monteggia LM, Pieper AA. Correction: D-cycloserine improves synaptic transmission in an animal mode of Rett syndrome. Plos One. 13: e0192057. PMID 29370281 DOI: 10.1371/journal.pone.0192057  1
2017 Burgdorf CE, Schierberl KC, Lee AS, Fischer DK, Van Kempen TA, Mudragel V, Huganir RL, Milner TA, Glass MJ, Rajadhyaksha AM. Extinction of contextual cocaine memories requires Cav1.2 within D1R-expressing cells and recruits hippocampal Cav1.2-dependent signaling mechanisms. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29089442 DOI: 10.1523/JNEUROSCI.2397-17.2017  1
2017 Na ES, De Jesús-Cortés H, Martinez-Rivera A, Kabir ZD, Wang J, Ramesh V, Onder Y, Rajadhyaksha AM, Monteggia LM, Pieper AA. D-cycloserine improves synaptic transmission in an animal mode of Rett syndrome. Plos One. 12: e0183026. PMID 28813484 DOI: 10.1371/journal.pone.0183026  1
2017 Fischer DK, Rice RC, Martinez-Rivera A, Donohoe M, Rajadhyaksha AM. Altered reward sensitivity in female offspring of cocaine-exposed fathers. Behavioural Brain Research. PMID 28552600 DOI: 10.1016/j.bbr.2017.05.054  0.4
2017 Kabir ZD, Martínez-Rivera A, Rajadhyaksha AM. From Gene to Behavior: L-Type Calcium Channel Mechanisms Underlying Neuropsychiatric Symptoms. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 28497380 DOI: 10.1007/s13311-017-0532-0  1
2017 Xu J, Lu Z, Narayan A, Le Rouzic VP, Xu M, Hunkele A, Brown TG, Hoefer WF, Rossi GC, Rice RC, Martínez-Rivera A, Rajadhyaksha AM, Cartegni L, Bassoni DL, Pasternak GW, et al. Alternatively spliced mu opioid receptor C termini impact the diverse actions of morphine. The Journal of Clinical Investigation. PMID 28319053 DOI: 10.1172/JCI88760  0.44
2017 Bavley CC, Fischer DK, Rizzo BK, Rajadhyaksha AM. Cav1.2 channels mediate persistent chronic stress-induced behavioral deficits that are associated with prefrontal cortex activation of the p25/Cdk5-glucocorticoid receptor pathway. Neurobiology of Stress. 7: 27-37. PMID 28289693 DOI: 10.1016/j.ynstr.2017.02.004  0.4
2016 Kabir ZD, Lee AS, Burgdorf CE, Fischer D, Rajadhyaksha AM, Mok E, Rizzo B, Rice RC, Singh K, Ota KT, Gerhard DM, Schierberl KC, Glass M, Duman RS, Rajadhyaksha AM. Cacna1c in the Prefrontal Cortex Regulates Depression-Related Behaviors via REDD1. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27922594 DOI: 10.1038/npp.2016.271  1
2016 Del Prete D, Rice RC, Rajadhyaksha AM, D'Adamio L. APP may act as a substrate and a recognition unit for CRL4CRBN and Stub1 E3 ligases facilitating ubiquitination of proteins involved in presynaptic functions and neurodegeneration. The Journal of Biological Chemistry. PMID 27325702 DOI: 10.1074/jbc.M116.733626  1
2016 Mende M, Fletcher EV, Belluardo JL, Pierce JP, Bommareddy PK, Weinrich JA, Kabir ZD, Schierberl KC, Pagiazitis JG, Mendelsohn AI, Francesconi A, Edwards RH, Milner TA, Rajadhyaksha AM, van Roessel PJ, et al. Sensory-Derived Glutamate Regulates Presynaptic Inhibitory Terminals in Mouse Spinal Cord. Neuron. PMID 27263971 DOI: 10.1016/j.neuron.2016.05.008  1
2016 Lee AS, De Jesús-Cortés H, Kabir ZD, Knobbe W, Orr M, Burgdorf C, Huntington P, McDaniel L, Britt JK, Hoffmann F, Brat DJ, Rajadhyaksha AM, Pieper AA. The Neuropsychiatric Disease-Associated Gene cacna1c Mediates Survival of Young Hippocampal Neurons. Eneuro. 3. PMID 27066530 DOI: 10.1523/ENEURO.0006-16.2016  1
2016 Kabir ZD, Lee AS, Rajadhyaksha AM. L-type Ca(2+) channels in mood, cognition and addiction: Integrating human and rodent studies with a focus on behavioural endophenotypes. The Journal of Physiology. PMID 26913808 DOI: 10.1113/JP270673  1
2014 Liu Y, Harding M, Pittman A, Dore J, Striessnig J, Rajadhyaksha A, Chen X. Cav1.2 and Cav1.3 L-type calcium channels regulate dopaminergic firing activity in the mouse ventral tegmental area. Journal of Neurophysiology. 112: 1119-30. PMID 24848473 DOI: 10.1152/jn.00757.2013  1
2013 Moeller S, Lau NM, Green PH, Hellberg D, Higgins JJ, Rajadhyaksha AM, Alaedini A. Lack of association between autism and anti-GM1 ganglioside antibody. Neurology. 81: 1640-1. PMID 24068789 DOI: 10.1212/WNL.0b013e3182a9f3dd  1
2013 Ajamian M, Rajadhyaksha AM, Alaedini A. Autism and Lyme disease--reply. Jama. 310: 857. PMID 23982381 DOI: 10.1001/jama.2013.194768  1
2013 Schierberl KC, Rajadhyaksha AM. Stereotaxic microinjection of viral vectors expressing Cre recombinase to study the role of target genes in cocaine conditioned place preference. Journal of Visualized Experiments : Jove. PMID 23929203 DOI: 10.3791/50600  1
2013 Lau NM, Green PH, Taylor AK, Hellberg D, Ajamian M, Tan CZ, Kosofsky BE, Higgins JJ, Rajadhyaksha AM, Alaedini A. Markers of Celiac Disease and Gluten Sensitivity in Children with Autism. Plos One. 8: e66155. PMID 23823064 DOI: 10.1371/journal.pone.0066155  1
2013 Ajamian M, Kosofsky BE, Wormser GP, Rajadhyaksha AM, Alaedini A. Serologic markers of Lyme disease in children with autism. Jama. 309: 1771-3. PMID 23632714 DOI: 10.1001/jama.2013.618  1
2012 Lee AS, Gonzales KL, Lee A, Moosmang S, Hofmann F, Pieper AA, Rajadhyaksha AM. Selective genetic deletion of cacna1c in the mouse prefrontal cortex. Molecular Psychiatry. 17: 1051. PMID 23096954 DOI: 10.1038/mp.2012.149  1
2012 Lee AS, Ra S, Rajadhyaksha AM, Britt JK, De Jesus-Cortes H, Gonzales KL, Lee A, Moosmang S, Hofmann F, Pieper AA, Rajadhyaksha AM. Forebrain elimination of cacna1c mediates anxiety-like behavior in mice. Molecular Psychiatry. 17: 1054-5. PMID 22665262 DOI: 10.1038/mp.2012.71  1
2012 Kabir ZD, Lourenco F, Byrne ME, Katzman A, Lee F, Rajadhyaksha AM, Kosofsky BE. Brain-derived neurotrophic factor genotype impacts the prenatal cocaine-induced mouse phenotype. Developmental Neuroscience. 34: 184-97. PMID 22572518 DOI: 10.1159/000337712  1
2012 Schierberl K, Giordano T, Satpute S, Hao J, Kaur G, Hofmann F, Moosmang S, Striessnig J, Rajadhyaksha A. Cav 1.3 L-type Ca ( 2+) channels mediate long-term adaptation in dopamine D2L-mediated GluA1 trafficking in the dorsal striatum following cocaine exposure. Channels (Austin, Tex.). 6: 11-7. PMID 22419037 DOI: 10.4161/chan.19324  1
2012 Rajadhyaksha AM, Ra S, Kishinevsky S, Lee AS, Romanienko P, DuBoff M, Yang C, Zupan B, Byrne M, Daruwalla ZR, Mark W, Kosofsky BE, Toth M, Higgins JJ. Behavioral characterization of cereblon forebrain-specific conditional null mice: a model for human non-syndromic intellectual disability. Behavioural Brain Research. 226: 428-34. PMID 21995942 DOI: 10.1016/j.bbr.2011.09.039  1
2012 Schierberl K, Giordano T, Satpute S, Hao J, Kaur G, Hofmann F, Moosmang S, Striessnig J, Rajadhyaksha A. Cav1.3 L-type Ca2+ channels mediate long-term adaptation in dopamine D2L-mediated GluA1 trafficking in the dorsal striatum following cocaine exposure Channels. 6. DOI: 10.4161/chan.6.1.19324  1
2011 Tropea TF, Kabir ZD, Kaur G, Rajadhyaksha AM, Kosofsky BE. Enhanced dopamine D1 and BDNF signaling in the adult dorsal striatum but not nucleus accumbens of prenatal cocaine treated mice. Frontiers in Psychiatry. 2: 67. PMID 22162970 DOI: 10.3389/fpsyt.2011.00067  1
2011 Schierberl K, Hao J, Tropea TF, Ra S, Giordano TP, Xu Q, Garraway SM, Hofmann F, Moosmang S, Striessnig J, Inturrisi CE, Rajadhyaksha AM. Cav1.2 L-type Ca²⁺ channels mediate cocaine-induced GluA1 trafficking in the nucleus accumbens, a long-term adaptation dependent on ventral tegmental area Ca(v)1.3 channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 13562-75. PMID 21940447 DOI: 10.1523/JNEUROSCI.2315-11.2011  1
2011 Ren JQ, Jiang Y, Wang Z, McCarthy D, Rajadhyaksha AM, Tropea TF, Kosofsky BE, Bhide PG. Prenatal L-DOPA exposure produces lasting changes in brain dopamine content, cocaine-induced dopamine release and cocaine conditioned place preference. Neuropharmacology. 60: 295-302. PMID 20854831 DOI: 10.1016/j.neuropharm.2010.09.012  1
2010 Giordano TP, Tropea TF, Satpute SS, Sinnegger-Brauns MJ, Striessnig J, Kosofsky BE, Rajadhyaksha AM. Molecular switch from L-type Ca v 1.3 to Ca v 1.2 Ca2+ channel signaling underlies long-term psychostimulant-induced behavioral and molecular plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 17051-62. PMID 21159975 DOI: 10.1523/JNEUROSCI.2255-10.2010  1
2010 Rajadhyaksha AM, Elemento O, Puffenberger EG, Schierberl KC, Xiang JZ, Putorti ML, Berciano J, Poulin C, Brais B, Michaelides M, Weleber RG, Higgins JJ. Mutations in FLVCR1 cause posterior column ataxia and retinitis pigmentosa. American Journal of Human Genetics. 87: 643-54. PMID 21070897 DOI: 10.1016/j.ajhg.2010.10.013  1
2010 Gregus AM, Inra CN, Giordano TP, Costa AC, Rajadhyaksha AM, Inturrisi CE. Spinal mediators that may contribute selectively to antinociceptive tolerance but not other effects of morphine as revealed by deletion of GluR5. Neuroscience. 169: 475-87. PMID 20359526 DOI: 10.1016/j.neuroscience.2010.03.051  1
2010 Higgins JJ, Tal AL, Sun X, Hauck SC, Hao J, Kosofosky BE, Rajadhyaksha AM. Temporal and spatial mouse brain expression of cereblon, an ionic channel regulator involved in human intelligence. Journal of Neurogenetics. 24: 18-26. PMID 20131966 DOI: 10.3109/01677060903567849  1
2010 Gregus AM, Tropea TF, Wang Y, Hauck SC, Costa AC, Rajadhyaksha AM, Inturrisi CE. Deletion of the GluR5 subunit of kainate receptors affects cocaine sensitivity and preference. Neuroscience Letters. 468: 186-9. PMID 19878705 DOI: 10.1016/j.neulet.2009.10.071  1
2009 Bogulavsky JJ, Gregus AM, Kim PT, Costa AC, Rajadhyaksha AM, Inturrisi CE. Deletion of the glutamate receptor 5 subunit of kainate receptors affects the development of morphine tolerance. The Journal of Pharmacology and Experimental Therapeutics. 328: 579-87. PMID 18957577 DOI: 10.1124/jpet.108.144121  1
2008 Tropea TF, Kosofsky BE, Rajadhyaksha AM. Enhanced CREB and DARPP-32 phosphorylation in the nucleus accumbens and CREB, ERK, and GluR1 phosphorylation in the dorsal hippocampus is associated with cocaine-conditioned place preference behavior. Journal of Neurochemistry. 106: 1780-90. PMID 18554320 DOI: 10.1111/j.1471-4159.2008.05518.x  1
2008 Higgins JJ, Hao J, Kosofsky BE, Rajadhyaksha AM. Dysregulation of large-conductance Ca2+-activated K+ channel expression in nonsyndromal mental retardation due to a cereblon p.R419X mutation. Neurogenetics. 9: 219-23. PMID 18414909 DOI: 10.1007/s10048-008-0128-2  1
2008 Covington HE, Tropea TF, Rajadhyaksha AM, Kosofsky BE, Miczek KA. NMDA receptors in the rat VTA: a critical site for social stress to intensify cocaine taking. Psychopharmacology. 197: 203-16. PMID 18097654 DOI: 10.1007/s00213-007-1024-4  1
2006 Giordano TP, Satpute SS, Striessnig J, Kosofsky BE, Rajadhyaksha AM. Up-regulation of dopamine D(2)L mRNA levels in the ventral tegmental area and dorsal striatum of amphetamine-sensitized C57BL/6 mice: role of Ca(v)1.3 L-type Ca(2+) channels. Journal of Neurochemistry. 99: 1197-206. PMID 17026527 DOI: 10.1111/j.1471-4159.2006.04186.x  1
2005 Rajadhyaksha AM, Kosofsky BE. Psychostimulants, Protein phosphorylation and Gene expression: a growing role of L-type calcium channels. Cellscience. 2: 127-144. PMID 16724157 DOI: 10.1901/jaba.2005.2-127  1
2005 Rajadhyaksha AM, Kosofsky BE. Psychostimulants, L-type calcium channels, kinases, and phosphatases. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 11: 494-502. PMID 16151049 DOI: 10.1177/1073858405278236  1
2005 Guerriero RM, Rajadhyaksha A, Crozatier C, Giros B, Nosten-Bertrand M, Kosofsky BE. Augmented constitutive CREB expression in the nucleus accumbens and striatum may contribute to the altered behavioral response to cocaine of adult mice exposed to cocaine in utero. Developmental Neuroscience. 27: 235-48. PMID 16046859 DOI: 10.1159/000085997  1
2004 Eaton ME, Macías W, Youngs RM, Rajadhyaksha A, Dudman JT, Konradi C. L-type Ca2+ channel blockers promote Ca2+ accumulation when dopamine receptors are activated in striatal neurons. Brain Research. Molecular Brain Research. 131: 65-72. PMID 15530653 DOI: 10.1016/j.molbrainres.2004.08.007  1
2004 Rajadhyaksha A, Husson I, Satpute SS, Küppenbender KD, Ren JQ, Guerriero RM, Standaert DG, Kosofsky BE. L-type Ca2+ channels mediate adaptation of extracellular signal-regulated kinase 1/2 phosphorylation in the ventral tegmental area after chronic amphetamine treatment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7464-76. PMID 15329393 DOI: 10.1523/JNEUROSCI.0612-04.2004  1
2003 Dudman JT, Eaton ME, Rajadhyaksha A, Macías W, Taher M, Barczak A, Kameyama K, Huganir R, Konradi C. Dopamine D1 receptors mediate CREB phosphorylation via phosphorylation of the NMDA receptor at Ser897-NR1. Journal of Neurochemistry. 87: 922-34. PMID 14622123 DOI: 10.1046/j.1471-4159.2003.02067.x  1
2001 Macías W, Carlson R, Rajadhyaksha A, Barczak A, Konradi C. Potassium chloride depolarization mediates CREB phosphorylation in striatal neurons in an NMDA receptor-dependent manner. Brain Research. 890: 222-32. PMID 11164788 DOI: 10.1016/S0006-8993(00)03163-2  1
2000 Leveque JC, Macías W, Rajadhyaksha A, Carlson RR, Barczak A, Kang S, Li XM, Coyle JT, Huganir RL, Heckers S, Konradi C. Intracellular modulation of NMDA receptor function by antipsychotic drugs. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 4011-20. PMID 10818136  1
1999 Rajadhyaksha A, Barczak A, Macías W, Leveque JC, Lewis SE, Konradi C. L-Type Ca(2+) channels are essential for glutamate-mediated CREB phosphorylation and c-fos gene expression in striatal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 6348-59. PMID 10414964  1
1998 Rajadhyaksha A, Leveque J, Macías W, Barczak A, Konradi C. Molecular components of striatal plasticity: the various routes of cyclic AMP pathways. Developmental Neuroscience. 20: 204-15. PMID 9691194 DOI: 10.1159/000017314  1
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