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Hyuk W. Ko, Ph.D. - Publications

Affiliations: 
2004 Rutgers University, New Brunswick, New Brunswick, NJ, United States 
Area:
Neuroscience Biology, Genetics, Molecular Biology
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24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Lee H, Ko HW. Cell cycle-related kinase is a crucial regulator for ciliogenesis and Hedgehog signaling in embryonic mouse lung development. Journal of Biochemistry and Molecular Biology. 53: 367-372. DOI: 10.5483/Bmbrep.2020.53.7.295  0.337
2019 Shin JO, Song J, Choi HS, Lee J, Lee K, Ko HW, Bok J. Activation of sonic hedgehog signaling by a Smoothened agonist restores congenital defects in mouse models of endocrine-cerebro-osteodysplasia syndrome. Ebiomedicine. PMID 31662288 DOI: 10.1016/J.Ebiom.2019.10.016  0.357
2019 Kunova Bosakova M, Nita A, Gregor T, Varecha M, Gudernova I, Fafilek B, Barta T, Basheer N, Abraham SP, Balek L, Tomanova M, Fialova Kucerova J, Bosak J, Potesil D, Zieba J, ... ... Ko HW, et al. Fibroblast growth factor receptor influences primary cilium length through an interaction with intestinal cell kinase. Proceedings of the National Academy of Sciences of the United States of America. PMID 30782830 DOI: 10.1073/Pnas.1800338116  0.388
2017 Snouffer A, Brown D, Lee H, Walsh J, Lupu F, Norman R, Lechtreck K, Ko HW, Eggenschwiler J. Cell Cycle-Related Kinase (CCRK) regulates ciliogenesis and Hedgehog signaling in mice. Plos Genetics. 13: e1006912. PMID 28817564 DOI: 10.1371/Journal.Pgen.1006912  0.397
2017 You BH, Chae HS, Song J, Ko HW, Chin YW, Choi YH. α-Mangostin ameliorates dextran sulfate sodium-induced colitis through inhibition of NF-κB and MAPK pathways. International Immunopharmacology. 49: 212-221. PMID 28601023 DOI: 10.1016/J.Intimp.2017.05.040  0.31
2017 Park N, Song JE, Jeong S, Thi Tran T, Ko HW, Kim EY. Vaccinia-related kinase 3 (VRK3) sets the circadian period and amplitude by affecting the subcellular localization of clock proteins in mammalian cells. Biochemical and Biophysical Research Communications. PMID 28412365 DOI: 10.1016/J.Bbrc.2017.04.057  0.431
2016 Lee H, Ko HW. Ciliary smoothened-mediated noncanonical hedgehog signaling promotes tubulin acetylation. Biochemical and Biophysical Research Communications. PMID 27793670 DOI: 10.1016/J.Bbrc.2016.10.093  0.316
2016 Taylor SP, Bosakova MK, Varecha M, Balek L, Barta T, Trantirek L, Jelinkova I, Duran I, Vesela I, Forlenza KN, Martin JH, Hampl A, Bamshad M, Nickerson D, ... ... Ko HW, et al. An inactivating mutation in intestinal cell kinase, ICK, impairs hedgehog signaling and causes short rib-polydactyly syndrome. Human Molecular Genetics. PMID 27466187 DOI: 10.1093/Hmg/Ddw240  0.348
2015 Kang SW, Lee E, Cho E, Seo JH, Ko HW, Kim EY. Drosophila peptidyl-prolyl isomerase Pin1 modulates circadian rhythms via regulating levels of PERIOD. Biochemical and Biophysical Research Communications. 463: 235-40. PMID 25998391 DOI: 10.1016/J.Bbrc.2015.05.033  0.472
2014 Moon H, Song J, Shin JO, Lee H, Kim HK, Eggenschwiller JT, Bok J, Ko HW. Intestinal cell kinase, a protein associated with endocrine-cerebro-osteodysplasia syndrome, is a key regulator of cilia length and Hedgehog signaling. Proceedings of the National Academy of Sciences of the United States of America. 111: 8541-6. PMID 24853502 DOI: 10.1073/Pnas.1323161111  0.4
2012 Ko HW. The primary cilium as a multiple cellular signaling scaffold in development and disease Bmb Reports. 45: 427-432. PMID 22917026 DOI: 10.5483/Bmbrep.2012.45.8.167  0.33
2011 Chiu JC, Ko HW, Edery I. NEMO/NLK phosphorylates PERIOD to initiate a time-delay phosphorylation circuit that sets circadian clock speed. Cell. 145: 357-70. PMID 21514639 DOI: 10.1016/J.Cell.2011.04.002  0.737
2011 Qin J, Lin Y, Norman RX, Ko HW, Eggenschwiler JT. Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components. Proceedings of the National Academy of Sciences of the United States of America. 108: 1456-61. PMID 21209331 DOI: 10.1073/Pnas.1011410108  0.327
2011 Chiu JC, Ko HW, Edery I. Erratum: NEMO/NLK phosphorylates PERIOD to initiate a time-delay phosphorylation circuit that sets circadian clock speed (Cell (2011) 145 (357-370)) Cell. 145. DOI: 10.1016/J.Cell.2011.04.023  0.723
2010 Sun WC, Jeong EH, Jeong HJ, Ko HW, Edery I, Kim EY. Two distinct modes of PERIOD recruitment onto dCLOCK reveal a novel role for TIMELESS in circadian transcription. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 14458-69. PMID 20980603 DOI: 10.1523/Jneurosci.2366-10.2010  0.647
2010 Ko HW, Kim EY, Chiu J, Vanselow JT, Kramer A, Edery I. A hierarchical phosphorylation cascade that regulates the timing of PERIOD nuclear entry reveals novel roles for proline-directed kinases and GSK-3beta/SGG in circadian clocks. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 12664-75. PMID 20861372 DOI: 10.1523/Jneurosci.1586-10.2010  0.744
2010 Ko HW, Norman RX, Tran J, Fuller KP, Fukuda M, Eggenschwiler JT. Broad-minded links cell cycle-related kinase to cilia assembly and hedgehog signal transduction. Developmental Cell. 18: 237-47. PMID 20159594 DOI: 10.1016/J.Devcel.2009.12.014  0.387
2009 Norman RX, Ko HW, Huang V, Eun CM, Abler LL, Zhang Z, Sun X, Eggenschwiler JT. Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling. Human Molecular Genetics. 18: 1740-54. PMID 19286674 DOI: 10.1093/Hmg/Ddp113  0.352
2008 Low KH, Lim C, Ko HW, Edery I. Natural variation in the splice site strength of a clock gene and species-specific thermal adaptation. Neuron. 60: 1054-67. PMID 19109911 DOI: 10.1016/J.Neuron.2008.10.048  0.655
2008 Cho A, Ko HW, Eggenschwiler JT. FKBP8 cell-autonomously controls neural tube patterning through a Gli2- and Kif3a-dependent mechanism. Developmental Biology. 321: 27-39. PMID 18590716 DOI: 10.1016/J.Ydbio.2008.05.558  0.343
2007 Ko HW, DiMassa S, Kim EY, Bae K, Edery I. Cis-combination of the classic per(S) and per(L) mutations results in arrhythmic Drosophila with ectopic accumulation of hyperphosphorylated PERIOD protein. Journal of Biological Rhythms. 22: 488-501. PMID 18057324 DOI: 10.1177/0748730407306929  0.679
2007 Kim EY, Ko HW, Yu W, Hardin PE, Edery I. A DOUBLETIME kinase binding domain on the Drosophila PERIOD protein is essential for its hyperphosphorylation, transcriptional repression, and circadian clock function. Molecular and Cellular Biology. 27: 5014-28. PMID 17452449 DOI: 10.1128/Mcb.02339-06  0.665
2005 Ko HW, Edery I. Analyzing the degradation of PERIOD protein by the ubiquitin-proteasome pathway in cultured Drosophila cells. Methods in Enzymology. 393: 394-408. PMID 15817301 DOI: 10.1016/S0076-6879(05)93018-8  0.651
2002 Ko HW, Jiang J, Edery I. Role for Slimb in the degradation of Drosophila Period protein phosphorylated by Doubletime. Nature. 420: 673-8. PMID 12442174 DOI: 10.1038/Nature01272  0.698
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