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Kavitha Venkatesan, Ph.D. - Publications

Affiliations: 
2005 Boston University, Boston, MA, United States 
Area:
Biomedical Engineering, Molecular Biology, Biostatistics Biology
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33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Ghandi M, Huang FW, Jané-Valbuena J, Kryukov GV, Lo CC, McDonald ER, Barretina J, Gelfand ET, Bielski CM, Li H, Hu K, Andreev-Drakhlin AY, Kim J, Hess JM, Haas BJ, ... ... Venkatesan K, et al. Next-generation characterization of the Cancer Cell Line Encyclopedia. Nature. PMID 31068700 DOI: 10.1038/S41586-019-1186-3  0.428
2018 Barretina J, Caponigro G, Stransky N, Venkatesan K, Margolin AA, Kim S, Wilson CJ, Lehár J, Kryukov GV, Sonkin D, Reddy A, Liu M, Murray L, Berger MF, Monahan JE, et al. Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity. Nature. PMID 30559381 DOI: 10.1038/S41586-018-0722-X  0.367
2017 McDonald ER, de Weck A, Schlabach MR, Billy E, Mavrakis KJ, Hoffman GR, Belur D, Castelletti D, Frias E, Gampa K, Golji J, Kao I, Li L, Megel P, Perkins TA, ... ... Venkatesan K, et al. Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening. Cell. 170: 577-592.e10. PMID 28753431 DOI: 10.1016/J.Cell.2017.07.005  0.426
2017 Acker MG, Chen YP, LaMarche MJ, Chan HM, Fekkes P, Garcia-Fortanet J, LaRochelle JR, Antonakos B, Chen CH, Chen Z, Cooke VG, Dobson JR, Deng Z, Feng F, Firestone B, ... ... Venkatesan K, et al. Abstract 2084: Conformational activation and allosteric inhibition of SHP2 in RTK-driven cancers Cancer Research. 77: 2084-2084. DOI: 10.1158/1538-7445.Am2017-2084  0.368
2016 Chen YP, LaMarche MJ, Chan HM, Fekkes P, Garcia-Fortanet J, Acker MG, Antonakos B, Chen CH, Chen Z, Cooke VG, Dobson JR, Deng Z, Fei F, Firestone B, Fodor M, ... ... Venkatesan K, et al. Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases. Nature. PMID 27362227 DOI: 10.1038/Nature18621  0.354
2016 Mavrakis KJ, McDonald ER, Schlabach MR, Billy E, Hoffman GR, deWeck A, Ruddy DA, Venkatesan K, Yu J, McAllister G, Stump M, deBeaumont R, Ho S, Yue Y, Liu Y, et al. Disordered methionine metabolism in MTAP/CDKN2A deleted cancers leads to dependence on PRMT5. Science (New York, N.Y.). PMID 26912361 DOI: 10.1126/Science.Aad5944  0.41
2016 Mavrakis K, McDonald ER, Schlabach MR, Billy E, Hoffman GR, deWeck A, Ruddy DA, Venkatesan K, McAllister G, deBeaumont R, Ho S, Liu Y, Yan-Neale Y, Yang G, Lin F, et al. Abstract LB-017: Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to marked dependence on PRMT5 Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-017  0.4
2015 Stransky N, Ghandi M, Kryukov GV, Garraway LA, Lehár J, Liu M, Sonkin D, Kauffmann A, Venkatesan K, Edelman EJ, Riester M, Barretina J, Caponigro G, Schlegel R, Sellers WR, et al. Pharmacogenomic agreement between two cancer cell line data sets Nature. 528: 84-87. PMID 26570998 DOI: 10.1038/Nature15736  0.395
2015 Gao H, Korn JM, Ferretti S, Monahan JE, Wang Y, Singh M, Zhang C, Schnell C, Yang G, Zhang Y, Balbin OA, Barbe S, Cai H, Casey F, Chatterjee S, ... Venkatesan K, et al. High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response. Nature Medicine. PMID 26479923 DOI: 10.1038/Nm.3954  0.322
2015 Rothman DM, Gao X, George E, Rasmusson T, Bhatia D, Alimov I, Wang L, Kamel A, Hatsis P, Feng Y, Tutter A, Michaud G, McDonald E, Venkatesan K, Farley D, et al. Metabolic Enzyme Sulfotransferase 1A1 Is the Trigger for N-Benzyl Indole Carbinol Tumor Growth Suppression. Chemistry & Biology. 22: 1228-37. PMID 26364931 DOI: 10.1016/J.Chembiol.2015.06.025  0.306
2014 Chan HM, Jaffe JD, Wang Y, Zhang J, Huether R, Kryukov GV, Bhang HC, Taylor JE, Hu M, Englund NP, Yan F, Wang Z, McDonald ER, Wei L, Ma J, ... ... Venkatesan K, et al. Abstract 2930: Global chromatin profiling reveals NSD2 mutation in pediatric ALL Cancer Research. 74: 2930-2930. DOI: 10.1158/1538-7445.Am2014-2930  0.409
2014 Jeay S, Gaulis S, Ferretti S, Albrecht G, Barys L, Guthy D, Halilovic E, Ito M, Murakami M, Pornon A, Ruetz S, Venkatesan K, Yu J, Jensen M, Wiesmann M, et al. Abstract 2909: A gene signature composed of 13 p53 target genes predicts for response to NVP-CGM097, a novel p53-Mdm2 inhibitor, in cell lines and in human primary tumor xenograft models Cancer Research. 74: 2909-2909. DOI: 10.1158/1538-7445.Am2014-2909  0.375
2013 Jaffe JD, Wang Y, Chan HM, Zhang J, Huether R, Kryukov GV, Bhang HE, Taylor JE, Hu M, Englund NP, Yan F, Wang Z, Robert McDonald E, Wei L, Ma J, ... ... Venkatesan K, et al. Global chromatin profiling reveals NSD2 mutations in pediatric acute lymphoblastic leukemia. Nature Genetics. 45: 1386-91. PMID 24076604 DOI: 10.1038/Ng.2777  0.396
2012 Guagnano V, Kauffmann A, Wöhrle S, Stamm C, Ito M, Barys L, Pornon A, Yao Y, Li F, Zhang Y, Chen Z, Wilson CJ, Bordas V, Le Douget M, Gaither LA, ... Venkatesan K, et al. FGFR genetic alterations predict for sensitivity to NVP-BGJ398, a selective pan-FGFR inhibitor. Cancer Discovery. 2: 1118-33. PMID 23002168 DOI: 10.1158/2159-8290.Cd-12-0210  0.422
2012 Barretina J, Caponigro G, Stransky N, Venkatesan K, Margolin AA, Kim S, Wilson CJ, Lehár J, Kryukov GV, Sonkin D, Reddy A, Liu M, Murray L, Berger MF, Monahan JE, et al. The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity. Nature. 483: 603-7. PMID 22460905 DOI: 10.1038/Nature11003  0.435
2012 Porta DG, Guagnano V, Stamm C, Woehrle S, Kauffmann A, Yao Y, Brümmendorf T, Bordas V, Douget ML, Zhang Y, Chen Z, Ito M, Li F, Monahan J, Gaither A, ... ... Venkatesan K, et al. Abstract 854: Patient stratification strategies for NVP-BGJ398, a selective pan-FGFR inhibitor in phase I clinical trials Cancer Research. 72: 854-854. DOI: 10.1158/1538-7445.Am2012-854  0.42
2012 Stransky N, Kryukov GV, Caponigro G, Barretina J, Venkatesan K, Margolin AA, Wilson CJ, Lehar J, Jones MD, Palescandolo E, Sougnez C, Onofrio RC, MacConaill L, Ardlie K, Golub TR, et al. Abstract 5114: Integrative analysis of the Cancer Cell Line Encyclopedia reveals genetic and transcriptional predictors of compound sensitivity Cancer Research. 72: 5114-5114. DOI: 10.1158/1538-7445.Am2012-5114  0.453
2011 Vazquez A, Rual JF, Venkatesan K. Quality control methodology for high-throughput protein-protein interaction screening. Methods in Molecular Biology (Clifton, N.J.). 781: 279-94. PMID 21877286 DOI: 10.1007/978-1-61779-276-2_13  0.367
2011 Porta DG, Guagnano V, Yao Y, Kauffmann A, Stamm C, Chen Z, Zhang Y, Bordas V, Douget ML, Ito M, Li F, Monahan J, Gaither A, Borawski J, Wilson CJ, ... Venkatesan K, et al. Abstract C193: FGFR genetic alterations predict for sensitivity to NVP-BGJ398, a novel orally bioavailable, selective, and potent FGFR inhibitor. Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-C193  0.397
2010 Yan H, Venkatesan K, Beaver JE, Klitgord N, Yildirim MA, Hao T, Hill DE, Cusick ME, Perrimon N, Roth FP, Vidal M. A genome-wide gene function prediction resource for Drosophila melanogaster. Plos One. 5: e12139. PMID 20711346 DOI: 10.1371/Journal.Pone.0012139  0.315
2010 Venkatesan K, Stransky N, Margolin A, Reddy A, Raman P, Sonkin D, Jones M, Wilson C, Kim S, Warmuth M, Sellers W, Lehar J, Barretina J, Caponigro G, Garraway L, et al. Prediction of drug response using genomic signatures from the Cancer Cell Line Encyclopedia Clinical Cancer Research. 16. DOI: 10.1158/Diag-10-Pr2  0.409
2010 Stransky N, Venkatesan K, Barretina J, Caponigro G, Margolin A, Morrissey M, Raman P, Getz G, Berger M, Johannessen C, Callahan A, Morais P, Mahan S, Gupta S, Onofrio R, et al. Abstract PR4: Integrative analysis of genomic and pharmacologic data from the Cancer Cell Line Encyclopedia Clinical Cancer Research. 16. DOI: 10.1158/1078-0432.Tcmusa10-Pr4  0.432
2009 Zhong Q, Simonis N, Li QR, Charloteaux B, Heuze F, Klitgord N, Tam S, Yu H, Venkatesan K, Mou D, Swearingen V, Yildirim MA, Yan H, Dricot A, Szeto D, et al. Edgetic perturbation models of human inherited disorders. Molecular Systems Biology. 5: 321. PMID 19888216 DOI: 10.1038/Msb.2009.80  0.309
2009 Simonis N, Rual JF, Carvunis AR, Tasan M, Lemmens I, Hirozane-Kishikawa T, Hao T, Sahalie JM, Venkatesan K, Gebreab F, Cevik S, Klitgord N, Fan C, Braun P, Li N, et al. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Nature Methods. 6: 47-54. PMID 19123269 DOI: 10.1038/Nmeth.1279  0.362
2009 Cusick ME, Yu H, Smolyar A, Venkatesan K, Carvunis AR, Simonis N, Rual JF, Borick H, Braun P, Dreze M, Vandenhaute J, Galli M, Yazaki J, Hill DE, Ecker JR, et al. Literature-curated protein interaction datasets. Nature Methods. 6: 39-46. PMID 19116613 DOI: 10.1038/Nmeth.1284  0.315
2009 Venkatesan K, Rual JF, Vazquez A, Stelzl U, Lemmens I, Hirozane-Kishikawa T, Hao T, Zenkner M, Xin X, Goh KI, Yildirim MA, Simonis N, Heinzmann K, Gebreab F, Sahalie JM, et al. An empirical framework for binary interactome mapping. Nature Methods. 6: 83-90. PMID 19060904 DOI: 10.1038/Nmeth.1280  0.319
2009 Braun P, Tasan M, Dreze M, Barrios-Rodiles M, Lemmens I, Yu H, Sahalie JM, Murray RR, Roncari L, de Smet AS, Venkatesan K, Rual JF, Vandenhaute J, Cusick ME, Pawson T, et al. An experimentally derived confidence score for binary protein-protein interactions. Nature Methods. 6: 91-7. PMID 19060903 DOI: 10.1038/Nmeth.1281  0.335
2008 Yu H, Braun P, Yildirim MA, Lemmens I, Venkatesan K, Sahalie J, Hirozane-Kishikawa T, Gebreab F, Li N, Simonis N, Hao T, Rual JF, Dricot A, Vazquez A, Murray RR, et al. High-quality binary protein interaction map of the yeast interactome network. Science (New York, N.Y.). 322: 104-10. PMID 18719252 DOI: 10.1126/Science.1158684  0.325
2007 Pujana MA, Han JD, Starita LM, Stevens KN, Tewari M, Ahn JS, Rennert G, Moreno V, Kirchhoff T, Gold B, Assmann V, Elshamy WM, Rual JF, Levine D, Rozek LS, ... ... Venkatesan K, et al. Network modeling links breast cancer susceptibility and centrosome dysfunction. Nature Genetics. 39: 1338-49. PMID 17922014 DOI: 10.1038/Ng.2007.2  0.365
2007 Dupuy D, Bertin N, Hidalgo CA, Venkatesan K, Tu D, Lee D, Rosenberg J, Svrzikapa N, Blanc A, Carnec A, Carvunis AR, Pulak R, Shingles J, Reece-Hoyes J, Hunt-Newbury R, et al. Genome-scale analysis of in vivo spatiotemporal promoter activity in Caenorhabditis elegans. Nature Biotechnology. 25: 663-8. PMID 17486083 DOI: 10.1038/Nbt1305  0.35
2007 Calderwood MA, Venkatesan K, Xing L, Chase MR, Vazquez A, Holthaus AM, Ewence AE, Li N, Hirozane-Kishikawa T, Hill DE, Vidal M, Kieff E, Johannsen E. Epstein-Barr virus and virus human protein interaction maps. Proceedings of the National Academy of Sciences of the United States of America. 104: 7606-11. PMID 17446270 DOI: 10.1073/Pnas.0702332104  0.345
2005 Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, et al. Towards a proteome-scale map of the human protein-protein interaction network. Nature. 437: 1173-8. PMID 16189514 DOI: 10.1038/Nature04209  0.349
2003 Venkatesan K, McManus HR, Mello CC, Smith TF, Hansen U. Functional conservation between members of an ancient duplicated transcription factor family, LSF/Grainyhead. Nucleic Acids Research. 31: 4304-16. PMID 12888489 DOI: 10.1093/Nar/Gkg644  0.461
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