Lester I. Binder - Publications

Affiliations: 
Neuroscience Institute Graduate Program Northwestern University, Evanston, IL 
Area:
Neuroscience Biology, Cell Biology, Molecular Biology

117 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Tiernan CT, Ginsberg SD, Guillozet-Bongaarts AL, Ward SM, He B, Kanaan NM, Mufson EJ, Binder LI, Counts SE. Protein homeostasis gene dysregulation in pretangle-bearing nucleus basalis neurons during the progression of Alzheimer's disease. Neurobiology of Aging. 42: 80-90. PMID 27143424 DOI: 10.1016/J.Neurobiolaging.2016.02.031  0.833
2015 Violet M, Chauderlier A, Delattre L, Tardivel M, Chouala MS, Sultan A, Marciniak E, Humez S, Binder L, Kayed R, Lefebvre B, Bonnefoy E, Buée L, Galas MC. Prefibrillar Tau oligomers alter the nucleic acid protective function of Tau in hippocampal neurons in vivo. Neurobiology of Disease. 82: 540-51. PMID 26385829 DOI: 10.1016/J.Nbd.2015.09.003  0.508
2015 Mufson EJ, Mahady L, Waters D, Counts SE, Perez SE, DeKosky ST, Ginsberg SD, Ikonomovic MD, Scheff SW, Binder LI. Hippocampal plasticity during the progression of Alzheimer's disease. Neuroscience. PMID 25772787 DOI: 10.1016/J.Neuroscience.2015.03.006  0.378
2014 Ward SM, Himmelstein DS, Ren Y, Fu Y, Yu XW, Roberts K, Binder LI, Sahara N. TOC1: a valuable tool in assessing disease progression in the rTg4510 mouse model of tauopathy. Neurobiology of Disease. 67: 37-48. PMID 24631720 DOI: 10.1016/J.Nbd.2014.03.002  0.653
2014 Sahara N, Ren Y, Ward S, Binder LI, Suhara T, Higuchi M. Tau oligomers as potential targets for early diagnosis of tauopathy. Journal of Alzheimer's Disease : Jad. 40: S91-6. PMID 24595194 DOI: 10.3233/JAD-132429  0.542
2014 Mufson EJ, Ward S, Binder L. Prefibrillar tau oligomers in mild cognitive impairment and Alzheimer's disease. Neuro-Degenerative Diseases. 13: 151-3. PMID 24029627 DOI: 10.1159/000353687  0.443
2014 Kanaan NM, Himmelstein DS, Ward SM, Combs B, Binder LI. Tau Protein: Biology and Pathobiology Movement Disorders: Genetics and Models: Second Edition. 857-874. DOI: 10.1016/B978-0-12-405195-9.00056-1  0.778
2013 Jarero-Basulto JJ, Luna-Muñoz J, Mena R, Kristofikova Z, Ripova D, Perry G, Binder LI, Garcia-Sierra F. Proteolytic cleavage of polymeric tau protein by caspase-3: implications for Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 72: 1145-61. PMID 24226268 DOI: 10.1097/Nen.0000000000000013  0.847
2013 Ward SM, Himmelstein DS, Lancia JK, Fu Y, Patterson KR, Binder LI. TOC1: characterization of a selective oligomeric tau antibody. Journal of Alzheimer's Disease : Jad. 37: 593-602. PMID 23979027 DOI: 10.3233/Jad-131235  0.55
2013 Monroy-Ramírez HC, Basurto-Islas G, Mena R, Cisneros B, Binder LI, Avila J, Garcia-Sierra F. Alterations in the nuclear architecture produced by the overexpression of tau protein in neuroblastoma cells. Journal of Alzheimer's Disease : Jad. 36: 503-20. PMID 23635409 DOI: 10.3233/Jad-122401  0.817
2013 Kanaan NM, Pigino GF, Brady ST, Lazarov O, Binder LI, Morfini GA. Axonal degeneration in Alzheimer's disease: when signaling abnormalities meet the axonal transport system. Experimental Neurology. 246: 44-53. PMID 22721767 DOI: 10.1016/J.Expneurol.2012.06.003  0.713
2012 Ward SM, Himmelstein DS, Lancia JK, Binder LI. Tau oligomers and tau toxicity in neurodegenerative disease. Biochemical Society Transactions. 40: 667-71. PMID 22817713 DOI: 10.1042/Bst20120134  0.63
2012 Himmelstein DS, Ward SM, Lancia JK, Patterson KR, Binder LI. Tau as a therapeutic target in neurodegenerative disease. Pharmacology & Therapeutics. 136: 8-22. PMID 22790092 DOI: 10.1016/J.Pharmthera.2012.07.001  0.598
2012 Nakamura K, Greenwood A, Binder L, Bigio EH, Denial S, Nicholson L, Zhou XZ, Lu KP. Proline isomer-specific antibodies reveal the early pathogenic tau conformation in Alzheimer's disease. Cell. 149: 232-44. PMID 22464332 DOI: 10.1016/J.Cell.2012.02.016  0.552
2012 Youmans KL, Tai LM, Kanekiyo T, Stine WB, Michon SC, Nwabuisi-Heath E, Manelli AM, Fu Y, Riordan S, Eimer WA, Binder L, Bu G, Yu C, Hartley DM, LaDu MJ. Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody. Molecular Neurodegeneration. 7: 8. PMID 22423893 DOI: 10.1186/1750-1326-7-8  0.44
2012 Voss K, Combs B, Patterson KR, Binder LI, Gamblin TC. Hsp70 alters tau function and aggregation in an isoform specific manner. Biochemistry. 51: 888-98. PMID 22236337 DOI: 10.1021/Bi2018078  0.842
2012 Mufson EJ, Binder L, Counts SE, DeKosky ST, de Toledo-Morrell L, Ginsberg SD, Ikonomovic MD, Perez SE, Scheff SW. Mild cognitive impairment: pathology and mechanisms. Acta Neuropathologica. 123: 13-30. PMID 22101321 DOI: 10.1007/S00401-011-0884-1  0.375
2012 Reyes JF, Geula C, Vana L, Binder LI. Selective tau tyrosine nitration in non-AD tauopathies. Acta Neuropathologica. 123: 119-32. PMID 22057784 DOI: 10.1007/S00401-011-0898-8  0.826
2012 García-Sierra F, Jarero-Basulto JJ, Kristofikova Z, Majer E, Binder LI, Ripova D. Ubiquitin is associated with early truncation of tau protein at aspartic acid(421) during the maturation of neurofibrillary tangles in Alzheimer's disease. Brain Pathology (Zurich, Switzerland). 22: 240-50. PMID 21919991 DOI: 10.1111/J.1750-3639.2011.00525.X  0.602
2012 Kanaan NM, Morfini G, Pigino G, LaPointe NE, Andreadis A, Song Y, Leitman E, Binder LI, Brady ST. Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport. Neurobiology of Aging. 33: 826.e15-30. PMID 21794954 DOI: 10.1016/J.Neurobiolaging.2011.06.006  0.865
2011 Patterson KR, Ward SM, Combs B, Voss K, Kanaan NM, Morfini G, Brady ST, Gamblin TC, Binder LI. Heat shock protein 70 prevents both tau aggregation and the inhibitory effects of preexisting tau aggregates on fast axonal transport. Biochemistry. 50: 10300-10. PMID 22039833 DOI: 10.1021/Bi2009147  0.854
2011 Vana L, Kanaan NM, Ugwu IC, Wuu J, Mufson EJ, Binder LI. Progression of tau pathology in cholinergic Basal forebrain neurons in mild cognitive impairment and Alzheimer's disease. The American Journal of Pathology. 179: 2533-50. PMID 21945902 DOI: 10.1016/J.Ajpath.2011.07.044  0.756
2011 Yamada K, Cirrito JR, Stewart FR, Jiang H, Finn MB, Holmes BB, Binder LI, Mandelkow EM, Diamond MI, Lee VM, Holtzman DM. In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 13110-7. PMID 21917794 DOI: 10.1523/Jneurosci.2569-11.2011  0.628
2011 Landahl EC, Antipova O, Bongaarts A, Barrea R, Berry R, Binder LI, Irving T, Orgel J, Vana L, Rice SE. X-ray diffraction from intact tau aggregates in human brain tissue. Nuclear Instruments & Methods in Physics Research. Section a, Accelerators, Spectrometers, Detectors and Associated Equipment. 649: 184-187. PMID 21876609 DOI: 10.1016/J.Nima.2011.01.059  0.384
2011 Kanaan NM, Morfini GA, LaPointe NE, Pigino GF, Patterson KR, Song Y, Andreadis A, Fu Y, Brady ST, Binder LI. Pathogenic forms of tau inhibit kinesin-dependent axonal transport through a mechanism involving activation of axonal phosphotransferases. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 9858-68. PMID 21734277 DOI: 10.1523/Jneurosci.0560-11.2011  0.844
2011 Patterson KR, Remmers C, Fu Y, Brooker S, Kanaan NM, Vana L, Ward S, Reyes JF, Philibert K, Glucksman MJ, Binder LI. Characterization of prefibrillar Tau oligomers in vitro and in Alzheimer disease. The Journal of Biological Chemistry. 286: 23063-76. PMID 21550980 DOI: 10.1074/Jbc.M111.237974  0.865
2011 Reyes JF, Fu Y, Vana L, Kanaan NM, Binder LI. Tyrosine nitration within the proline-rich region of Tau in Alzheimer's disease. The American Journal of Pathology. 178: 2275-85. PMID 21514440 DOI: 10.1016/J.Ajpath.2011.01.030  0.865
2011 Vana L, Kanaan NM, Hakala K, Weintraub ST, Binder LI. Peroxynitrite-induced nitrative and oxidative modifications alter tau filament formation. Biochemistry. 50: 1203-12. PMID 21210655 DOI: 10.1021/Bi101735M  0.773
2010 Oh KJ, Perez SE, Lagalwar S, Vana L, Binder L, Mufson EJ. Staging of Alzheimer's pathology in triple transgenic mice: a light and electron microscopic analysis. International Journal of Alzheimer's Disease. 2010. PMID 20798886 DOI: 10.4061/2010/780102  0.785
2009 Lapointe NE, Horowitz PM, Guillozet-Bongaarts AL, Silva A, Andreadis A, Binder LI. Tau 6D and 6P isoforms inhibit polymerization of full-length tau in vitro. Biochemistry. 48: 12290-7. PMID 19919107 DOI: 10.1021/Bi901304U  0.84
2009 Morfini GA, Burns M, Binder LI, Kanaan NM, LaPointe N, Bosco DA, Brown RH, Brown H, Tiwari A, Hayward L, Edgar J, Nave KA, Garberrn J, Atagi Y, Song Y, et al. Axonal transport defects in neurodegenerative diseases. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 12776-86. PMID 19828789 DOI: 10.1523/Jneurosci.3463-09.2009  0.782
2009 Dickey C, Kraft C, Jinwal U, Koren J, Johnson A, Anderson L, Lebson L, Lee D, Dickson D, de Silva R, Binder LI, Morgan D, Lewis J. Aging analysis reveals slowed tau turnover and enhanced stress response in a mouse model of tauopathy. The American Journal of Pathology. 174: 228-38. PMID 19074615 DOI: 10.2353/Ajpath.2009.080764  0.621
2009 LaPointe NE, Morfini G, Pigino G, Gaisina IN, Kozikowski AP, Binder LI, Brady ST. The amino terminus of tau inhibits kinesin-dependent axonal transport: implications for filament toxicity. Journal of Neuroscience Research. 87: 440-51. PMID 18798283 DOI: 10.1002/Jnr.21850  0.833
2009 Mondragón-Rodríguez S, Basurto-Islas G, Binder LI, García-Sierra F. Conformational changes and cleavage; are these responsible for the tau aggregation in Alzheimer's disease? Future Neurology. 4: 39-53. DOI: 10.2217/14796708.4.1.39  0.826
2009 Basurto-Islas G, Mondragón-Rodríguez S, Binder LI, García-Sierra F. Pathology of the cleaved tau protein in the context of toxicity and the formation of neurofibrillary tangles European Neurological Review. 4: 20-23. DOI: 10.17925/Enr.2009.04.02.20  0.861
2008 Reyes JF, Reynolds MR, Horowitz PM, Fu Y, Guillozet-Bongaarts AL, Berry R, Binder LI. A possible link between astrocyte activation and tau nitration in Alzheimer's disease. Neurobiology of Disease. 31: 198-208. PMID 18562203 DOI: 10.1016/J.Nbd.2008.04.005  0.865
2008 Sahara N, Murayama M, Lee B, Park JM, Lagalwar S, Binder LI, Takashima A. Active c-jun N-terminal kinase induces caspase cleavage of tau and additional phosphorylation by GSK-3beta is required for tau aggregation. The European Journal of Neuroscience. 27: 2897-906. PMID 18540881 DOI: 10.1111/J.1460-9568.2008.06258.X  0.824
2008 Basurto-Islas G, Luna-Muñoz J, Guillozet-Bongaarts AL, Binder LI, Mena R, García-Sierra F. Accumulation of aspartic acid421- and glutamic acid391-cleaved tau in neurofibrillary tangles correlates with progression in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 67: 470-83. PMID 18431250 DOI: 10.1097/Nen.0B013E31817275C7  0.607
2008 Mondragón-Rodríguez S, Basurto-Islas G, Santa-Maria I, Mena R, Binder LI, Avila J, Smith MA, Perry G, García-Sierra F. Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer's disease. International Journal of Experimental Pathology. 89: 81-90. PMID 18336525 DOI: 10.1111/J.1365-2613.2007.00568.X  0.611
2008 Mondragón-Rodríguez S, Mena R, Binder LI, Smith MA, Perry G, García-Sierra F. Conformational changes and cleavage of tau in Pick bodies parallel the early processing of tau found in Alzheimer pathology. Neuropathology and Applied Neurobiology. 34: 62-75. PMID 17971079 DOI: 10.1111/J.1365-2990.2007.00853.X  0.638
2008 Binder LI. PL-02-01: Tau modifications, aggregation and toxicity Alzheimer's & Dementia. 4: T122-T122. DOI: 10.1016/J.Jalz.2008.05.265  0.548
2007 Reynolds MR, Berry RW, Binder LI. Nitration in neurodegeneration: deciphering the "Hows" "nYs". Biochemistry. 46: 7325-36. PMID 17542619 DOI: 10.1021/Bi700430Y  0.426
2007 Zhao J, Fu Y, Yasvoina M, Shao P, Hitt B, O'Connor T, Logan S, Maus E, Citron M, Berry R, Binder L, Vassar R. Beta-site amyloid precursor protein cleaving enzyme 1 levels become elevated in neurons around amyloid plaques: implications for Alzheimer's disease pathogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 3639-49. PMID 17409228 DOI: 10.1523/Jneurosci.4396-06.2007  0.507
2007 Guillozet-Bongaarts AL, Glajch KE, Libson EG, Cahill ME, Bigio E, Berry RW, Binder LI. Phosphorylation and cleavage of tau in non-AD tauopathies. Acta Neuropathologica. 113: 513-20. PMID 17357802 DOI: 10.1007/S00401-007-0209-6  0.62
2007 Lagalwar S, Berry RW, Binder LI. Relation of hippocampal phospho-SAPK/JNK granules in Alzheimer's disease and tauopathies to granulovacuolar degeneration bodies. Acta Neuropathologica. 113: 63-73. PMID 17089132 DOI: 10.1007/S00401-006-0159-4  0.812
2006 Sengupta S, Horowitz PM, Karsten SL, Jackson GR, Geschwind DH, Fu Y, Berry RW, Binder LI. Degradation of tau protein by puromycin-sensitive aminopeptidase in vitro. Biochemistry. 45: 15111-9. PMID 17154549 DOI: 10.1021/Bi061830D  0.775
2006 Reynolds MR, Reyes JF, Fu Y, Bigio EH, Guillozet-Bongaarts AL, Berry RW, Binder LI. Tau nitration occurs at tyrosine 29 in the fibrillar lesions of Alzheimer's disease and other tauopathies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 10636-45. PMID 17050703 DOI: 10.1523/Jneurosci.2143-06.2006  0.838
2006 Horowitz PM, LaPointe N, Guillozet-Bongaarts AL, Berry RW, Binder LI. N-terminal fragments of tau inhibit full-length tau polymerization in vitro. Biochemistry. 45: 12859-66. PMID 17042504 DOI: 10.1021/Bi061325G  0.85
2006 Karsten SL, Sang TK, Gehman LT, Chatterjee S, Liu J, Lawless GM, Sengupta S, Berry RW, Pomakian J, Oh HS, Schulz C, Hui KS, Wiedau-Pazos M, Vinters HV, Binder LI, et al. A genomic screen for modifiers of tauopathy identifies puromycin-sensitive aminopeptidase as an inhibitor of tau-induced neurodegeneration. Neuron. 51: 549-60. PMID 16950154 DOI: 10.1016/J.Neuron.2006.07.019  0.562
2006 Lagalwar S, Guillozet-Bongaarts AL, Berry RW, Binder LI. Formation of phospho-SAPK/JNK granules in the hippocampus is an early event in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 65: 455-64. PMID 16772869 DOI: 10.1097/01.Jnen.0000229236.98124.D8  0.821
2006 Guillozet-Bongaarts AL, Cahill ME, Cryns VL, Reynolds MR, Berry RW, Binder LI. Pseudophosphorylation of tau at serine 422 inhibits caspase cleavage: in vitro evidence and implications for tangle formation in vivo. Journal of Neurochemistry. 97: 1005-14. PMID 16606369 DOI: 10.1111/J.1471-4159.2006.03784.X  0.592
2006 Reynolds MR, Lukas TJ, Berry RW, Binder LI. Peroxynitrite-mediated tau modifications stabilize preformed filaments and destabilize microtubules through distinct mechanisms. Biochemistry. 45: 4314-26. PMID 16566606 DOI: 10.1021/Bi052142H  0.626
2006 Binder L. S3-03-02: Tau cleavage Alzheimer's & Dementia. 2: S48-S48. DOI: 10.1016/j.jalz.2006.05.175  0.462
2005 Reynolds MR, Berry RW, Binder LI. Site-specific nitration differentially influences tau assembly in vitro. Biochemistry. 44: 13997-4009. PMID 16229489 DOI: 10.1021/Bi051028W  0.617
2005 Mufson EJ, Counts SE, Perez SE, Binder L. Galanin plasticity in the cholinergic basal forebrain in Alzheimer's disease and transgenic mice. Neuropeptides. 39: 233-7. PMID 15893372 DOI: 10.1016/J.Npep.2004.12.005  0.503
2005 Guillozet-Bongaarts AL, Garcia-Sierra F, Reynolds MR, Horowitz PM, Fu Y, Wang T, Cahill ME, Bigio EH, Berry RW, Binder LI. Tau truncation during neurofibrillary tangle evolution in Alzheimer's disease. Neurobiology of Aging. 26: 1015-22. PMID 15748781 DOI: 10.1016/J.Neurobiolaging.2004.09.019  0.866
2005 Reynolds MR, Berry RW, Binder LI. Site-specific nitration and oxidative dityrosine bridging of the tau protein by peroxynitrite: implications for Alzheimer's disease. Biochemistry. 44: 1690-700. PMID 15683253 DOI: 10.1021/Bi047982V  0.659
2005 Binder LI, Guillozet-Bongaarts AL, Garcia-Sierra F, Berry RW. Tau, tangles, and Alzheimer's disease. Biochimica Et Biophysica Acta. 1739: 216-23. PMID 15615640 DOI: 10.1016/J.Bbadis.2004.08.014  0.843
2004 Berry RW, Sweet AP, Clark FA, Lagalwar S, Lapin BR, Wang T, Topgi S, Guillozet-Bongaarts AL, Cochran EJ, Bigio EH, Binder LI. Tau epitope display in progressive supranuclear palsy and corticobasal degeneration. Journal of Neurocytology. 33: 287-95. PMID 15475684 DOI: 10.1023/B:Neur.0000044190.96426.B9  0.854
2004 Horowitz PM, Patterson KR, Guillozet-Bongaarts AL, Reynolds MR, Carroll CA, Weintraub ST, Bennett DA, Cryns VL, Berry RW, Binder LI. Early N-terminal changes and caspase-6 cleavage of tau in Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7895-902. PMID 15356202 DOI: 10.1523/Jneurosci.1988-04.2004  0.763
2004 Binder LI, Guillozet-Bongaarts A, Garcia-Sierra F, Berry RW. Use of antibodies and microscopy to ascertain the structure of tau in the neurofibrillary tangles of Alzheimer's disease Microscopy and Microanalysis. 10: 1548-1549. DOI: 10.1017/S1431927604887646  0.812
2003 Gamblin TC, Berry RW, Binder LI. Modeling tau polymerization in vitro: a review and synthesis. Biochemistry. 42: 15009-17. PMID 14690409 DOI: 10.1021/Bi035722S  0.596
2003 Gamblin TC, Chen F, Zambrano A, Abraha A, Lagalwar S, Guillozet AL, Lu M, Fu Y, Garcia-Sierra F, LaPointe N, Miller R, Berry RW, Binder LI, Cryns VL. Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 100: 10032-7. PMID 12888622 DOI: 10.1073/Pnas.1630428100  0.855
2003 Hogg M, Grujic ZM, Baker M, Demirci S, Guillozet AL, Sweet AP, Herzog LL, Weintraub S, Mesulam MM, LaPointe NE, Gamblin TC, Berry RW, Binder LI, de Silva R, Lees A, et al. The L266V tau mutation is associated with frontotemporal dementia and Pick-like 3R and 4R tauopathy. Acta Neuropathologica. 106: 323-36. PMID 12883828 DOI: 10.1007/S00401-003-0734-X  0.779
2003 Berry RW, Abraha A, Lagalwar S, LaPointe N, Gamblin TC, Cryns VL, Binder LI. Inhibition of tau polymerization by its carboxy-terminal caspase cleavage fragment. Biochemistry. 42: 8325-31. PMID 12846581 DOI: 10.1021/Bi027348M  0.856
2003 García-Sierra F, Ghoshal N, Quinn B, Berry RW, Binder LI. Conformational changes and truncation of tau protein during tangle evolution in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 5: 65-77. PMID 12719624 DOI: 10.3233/Jad-2003-5201  0.72
2003 Gamblin TC, Berry RW, Binder LI. Tau polymerization: role of the amino terminus. Biochemistry. 42: 2252-7. PMID 12590615 DOI: 10.1021/Bi0272510  0.598
2002 Ghoshal N, García-Sierra F, Wuu J, Leurgans S, Bennett DA, Berry RW, Binder LI. Tau conformational changes correspond to impairments of episodic memory in mild cognitive impairment and Alzheimer's disease. Experimental Neurology. 177: 475-93. PMID 12429193 DOI: 10.1006/Exnr.2002.8014  0.683
2002 Rapoport M, Dawson HN, Binder LI, Vitek MP, Ferreira A. Tau is essential to beta -amyloid-induced neurotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 99: 6364-9. PMID 11959919 DOI: 10.1073/Pnas.092136199  0.605
2001 Berry RW, Quinn B, Johnson N, Cochran EJ, Ghoshal N, Binder LI. Pathological glial tau accumulations in neurodegenerative disease: review and case report. Neurochemistry International. 39: 469-79. PMID 11578782 DOI: 10.1016/S0197-0186(01)00054-7  0.727
2001 Ghoshal N, García-Sierra F, Fu Y, Beckett LA, Mufson EJ, Kuret J, Berry RW, Binder LI. Tau-66: evidence for a novel tau conformation in Alzheimer's disease. Journal of Neurochemistry. 77: 1372-85. PMID 11389188 DOI: 10.1046/J.1471-4159.2001.00346.X  0.784
2001 King ME, Ghoshal N, Wall JS, Binder LI, Ksiezak-Reding H. Structural analysis of Pick's disease-derived and in vitro-assembled tau filaments. The American Journal of Pathology. 158: 1481-90. PMID 11290566 DOI: 10.1016/S0002-9440(10)64099-0  0.84
2001 Dawson HN, Ferreira A, Eyster MV, Ghoshal N, Binder LI, Vitek MP. Inhibition of neuronal maturation in primary hippocampal neurons from tau deficient mice. Journal of Cell Science. 114: 1179-87. PMID 11228161  0.661
2000 Gamblin TC, King ME, Kuret J, Berry RW, Binder LI. Oxidative regulation of fatty acid-induced tau polymerization Biochemistry. 39: 14203-14210. PMID 11087369 DOI: 10.1021/Bi001876L  0.74
2000 Abraha A, Ghoshal N, Gamblin TC, Cryns V, Berry RW, Kuret J, Binder LI. C-terminal inhibition of tau assembly in vitro and in Alzheimer's disease. Journal of Cell Science. 113: 3737-45. PMID 11034902  0.745
2000 Schwab C, DeMaggio AJ, Ghoshal N, Binder LI, Kuret J, McGeer PL. Casein kinase 1 delta is associated with pathological accumulation of tau in several neurodegenerative diseases. Neurobiology of Aging. 21: 503-10. PMID 10924763 DOI: 10.1016/S0197-4580(00)00110-X  0.709
2000 Gamblin TC, King ME, Dawson H, Vitek MP, Kuret J, Berry RW, Binder LI. In vitro polymerization of tau protein monitored by laser light scattering: Method and application to the study of FTDP-17 mutants Biochemistry. 39: 6136-6144. PMID 10821687 DOI: 10.1021/Bi000201F  0.753
2000 King ME, Gamblin TC, Kuret J, Binder LI. Differential assembly of human tau isoforms in the presence of arachidonic acid Journal of Neurochemistry. 74: 1749-1757. PMID 10737634 DOI: 10.1046/j.1471-4159.2000.0741749.x  0.754
2000 Kuret J, Abraha A, Gamblin TC, Grau L, King ME, Binder LI. The structural basis of tau filament formation Neurobiology of Aging. 21: 132-133. DOI: 10.1016/S0197-4580(00)82395-7  0.771
2000 Kuret J, Binder LI, Hoekstra MF, Demaggio AJ. A new molecular link between granulovacuolar and neurofibrillary lesions of Alzheimer's disease Neurobiology of Aging. 21: 191. DOI: 10.1016/S0197-4580(00)82202-2  0.4
1999 King ME, Ahuja V, Binder LI, Kuret J. Ligand-dependent tau filament formation: Implications for Alzheimer's disease progression Biochemistry. 38: 14851-14859. PMID 10555967 DOI: 10.1021/Bi9911839  0.805
1999 Ghoshal N, Smiley JF, DeMaggio AJ, Hoekstra MF, Cochran EJ, Binder LI, Kuret J. A new molecular link between the fibrillar and granulovacuolar lesions of Alzheimer's disease. The American Journal of Pathology. 155: 1163-72. PMID 10514399 DOI: 10.1016/S0002-9440(10)65219-4  0.719
1997 Thurston VC, Pena P, Pestell R, Binder LI. Nucleolar localization of the microtubule-associated protein tau in neuroblastomas using sense and anti-sense transfection strategies Cell Motility and the Cytoskeleton. 38: 100-110. PMID 9295144 DOI: 10.1002/(Sici)1097-0169(1997)38:1<100::Aid-Cm9>3.0.Co;2-C  0.579
1997 Wilson DM, Binder LI. Free fatty acids stimulate the polymerization of tau and amyloid β peptides: In vitro evidence for a common effector of pathogenesis in Alzheimer's disease American Journal of Pathology. 150: 2181-2195. PMID 9176408  0.496
1996 Carmel G, Mager EM, Binder LI, Kuret J. The structural basis of monoclonal antibody Alz50's selectivity for Alzheimer's disease pathology Journal of Biological Chemistry. 271: 32789-32795. PMID 8955115 DOI: 10.1074/Jbc.271.51.32789  0.501
1996 Thurston VC, Zinkowski RP, Binder LI. Tau as a nucleolar protein in human nonneural cells in vitro and in vivo Chromosoma. 105: 20-30. PMID 8662255 DOI: 10.1007/Bf02510035  0.53
1995 Wilson DM, Binder LI. Polymerization of microtubule-associated protein tau under near-physiological conditions Journal of Biological Chemistry. 270: 24306-24314. PMID 7592641  0.563
1995 Rady RM, Zinkowski RP, Binder LI. Presence of tau in isolated nuclei from human brain Neurobiology of Aging. 16: 479-486. PMID 7566354 DOI: 10.1016/0197-4580(95)00023-8  0.642
1995 LoPresti P, Szuchet S, Papasozomenos SC, Zinkowski RP, Binder LI. Functional implications for the microtubule-associated protein tau: localization in oligodendrocytes. Proceedings of the National Academy of Sciences of the United States of America. 92: 10369-73. PMID 7479786 DOI: 10.1073/Pnas.92.22.10369  0.565
1994 Riederer BM, Binder LI. Differential distribution of tau proteins in developing cat cerebellum Brain Research Bulletin. 33: 155-161. PMID 8275333 DOI: 10.1016/0361-9230(94)90245-3  0.514
1994 Binder LI, Ghanbari HA. Alzheimer's disease: a route to drug discovery. Neurobiology of Aging. 15: S35-6. PMID 7700456 DOI: 10.1016/0197-4580(94)90164-3  0.382
1993 Wang Y, Loomis PA, Zinkowski RP, Binder LI. A novel tau transcript in cultured human neuroblastoma cells expressing nuclear tau Journal of Cell Biology. 121: 257-267. PMID 8468346  0.417
1992 Greenberg SG, Davies P, Schein JD, Binder LI. Hydrofluoric acid-treated tau PHF proteins display the same biochemical properties as normal tau. The Journal of Biological Chemistry. 267: 564-9. PMID 1370450  0.566
1990 Loomis PA, Howard TH, Castleberry RP, Binder LI. Identification of nuclear T isoforms in human neuroblastoma cells Proceedings of the National Academy of Sciences of the United States of America. 87: 8422-8426. PMID 1700432  0.323
1990 Ksiezak-Reding H, Binder LI, Yen SH. Alzheimer disease proteins (A68) share epitopes with tau but show distinct biochemical properties Journal of Neuroscience Research. 25: 420-430. PMID 1691309  0.427
1990 Mori S, Sternberger NH, Herman MM, Rubinstein LJ, Binder LI, Sternberger LA. CONFORMATIONAL DEGENERATION OF NEUROFILAMENTS (Nf) IN ALZHEIMER DISEASE Journal of Neuropathology and Experimental Neurology. 49: 335. DOI: 10.1097/00005072-199005000-00228  0.326
1989 Zhang H, Sternberger NH, Rubinstein LJ, Herman MM, Binder LI, Sternberger LA. Abnormal processing of multiple proteins in Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 86: 8045-9. PMID 2813376  0.554
1989 Sternberger LA, Zhang H, Rubinstein LJ, Herman MM, Binder LI, Sternberger NH. Multiple proteins are abnormally processed in Alzheimer disease. Progress in Clinical and Biological Research. 317: 763-8. PMID 2690120  0.342
1989 Johnson GVW, Jope RS, Binder LI. Proteolysis of tau by calpain Biochemical and Biophysical Research Communications. 163: 1505-1511. PMID 2551295 DOI: 10.1016/0006-291X(89)91150-9  0.426
1988 Viereck C, Tucker RP, Binder LI, Matus A. Phylogenetic conservation of brain microtubule-associated proteins MAP2 and tau. Neuroscience. 26: 893-904. PMID 3143928 DOI: 10.1016/0306-4522(88)90107-8  0.338
1988 Ksiezak-Reding H, Binder LI, Yen SH. Immunochemical and biochemical characterization of τ proteins in normal and Alzheimer's disease brains with Alz 50 and Tau-1 Journal of Biological Chemistry. 263: 7948-7953. PMID 3131334  0.39
1987 Dotti CG, Banker GA, Binder LI. The expression and distribution of the microtubule-associated proteins tau and microtubule-associated protein 2 in hippocampal neurons in the rat in situ and in cell culture. Neuroscience. 23: 121-30. PMID 3120034 DOI: 10.1016/0306-4522(87)90276-4  0.428
1987 Papasozomenos SC, Binder LI. Phosphorylation determines two distinct species of Tau in the central nervous system. Cell Motility and the Cytoskeleton. 8: 210-26. PMID 2446784 DOI: 10.1002/cm.970080303  0.503
1987 Merz PA, Wrzolek M, Kascsak RJ, Grundke-Iqbal I, Iqbal K, Binder L, Kosik K, Wisniewski HM. IMMUNE ELECTRON MICROSCOPY OF PAIRED HELICAL FILAMENTS (PHF) WITH TAU ANTIBODIES Journal of Neuropathology and Experimental Neurology. 46: 376. DOI: 10.1097/00005072-198705000-00139  0.432
1987 Papasozomenos SC, Binder LI. PHOSPHORYLATED TAU PROTEIN IS PRESENT IN NEURONAL CELL BODIES AND DENDRITES OF CONTROL AND β,βʼ-IMINODIPROPIONITRILE (IDPN)-TREATED RATS. IMPLICATIONS FOR THE PATHOGENESIS OF ALZHEIMERʼS DISEASE (AD) Journal of Neuropathology and Experimental Neurology. 46: 349. DOI: 10.1097/00005072-198705000-00060  0.502
1987 Grundke-Iqbal I, Iqbal K, Tung Y, Quinlan M, Wisniewski H, Binder L. Abnormal phosphorylation of the microtubule-associated protein? (tau) in Alzheimer cytoskeletal pathology Alzheimer Disease & Associated Disorders. 1: 202. DOI: 10.1097/00002093-198701030-00020  0.631
1986 Grundke-Iqbal I, Iqbal K, Tung YC, Quinlan M, Wisniewski HM, Binder LI. Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology. Proceedings of the National Academy of Sciences of the United States of America. 83: 4913-7. PMID 3088567 DOI: 10.1073/Pnas.83.13.4913  0.589
1986 Wood JG, Mirra SS, Pollock NJ, Binder LI. Neurofibrillary tangles of Alzheimer disease share antigenic determinants with the axonal microtubule-associated protein tau (tau) Proceedings of the National Academy of Sciences of the United States of America. 83: 4040-3. PMID 2424015 DOI: 10.1073/Pnas.83.11.4040  0.648
1985 Binder LI, Frankfurter A, Rebhun LI. The distribution of tau in the mammalian central nervous system Journal of Cell Biology. 101: 1371-1378. PMID 3930508 DOI: 10.1083/Jcb.101.4.1371  0.566
1984 Caceres A, Binder LI, Payne MR, Bender P, Rebhun L, Steward O. Differential subcellular localization of tubulin and the microtubule-associated protein MAP2 in brain tissue as revealed by immunocytochemistry with monoclonal hybridoma antibodies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 4: 394-410. PMID 6699682 DOI: 10.1523/Jneurosci.04-02-00394.1984  0.381
1984 Binder LI, Frankfurter A, Kim H, Caceres A, Payne MR, Rebhun LI. Heterogeneity of microtubule-associated protein 2 during rat brain development. Proceedings of the National Academy of Sciences of the United States of America. 81: 5613-7. PMID 6591209 DOI: 10.1073/Pnas.81.17.5613  0.315
1983 Caceres A, Payne MR, Binder LI, Steward O. Immunocytochemical localization of actin and microtubule-associated protein MAP2 in dendritic spines. Proceedings of the National Academy of Sciences of the United States of America. 80: 1738-42. PMID 6572937 DOI: 10.1073/Pnas.80.6.1738  0.383
1979 Kim H, Binder LI, Rosenbaum JL. The periodic association of MAP2 with brain microtubules in vitro. The Journal of Cell Biology. 80: 266-76. PMID 457745 DOI: 10.1083/Jcb.80.2.266  0.58
1978 Binder LI, Rosenbaum JL. The in vitro assembly of flagellar outer doublet tubulin. The Journal of Cell Biology. 79: 500-15. PMID 569158  0.603
1975 Rosenbaum JL, Binder LI, Granett S, Dentler WL, Snell W, Sloboda R, Haimo L. Directionality and rate of assembly of chick brain tubulin onto pieces of neurotubules, flagellar axonemes, and basal bodies. Annals of the New York Academy of Sciences. 253: 147-77. PMID 1056739 DOI: 10.1111/J.1749-6632.1975.Tb19198.X  0.763
1975 Binder LI, Dentler WL, Rosenbaum JL. Assembly of chick brain tubulin onto flagellar microtubules from Chlamydomonas and sea urchin sperm. Proceedings of the National Academy of Sciences of the United States of America. 72: 1122-6. PMID 1055370 DOI: 10.1073/Pnas.72.3.1122  0.615
1974 Snell WJ, Dentler WL, Haimo LT, Binder LI, Rosenbaum JL. Assembly of chick brain tubulin onto isolated basal bodies of Chlamydomonas reinhardi. Science (New York, N.Y.). 185: 357-60. PMID 4834365 DOI: 10.1126/Science.185.4148.357  0.792
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