Richard J. Samulski - Publications

Neurobiology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Neuroscience Biology, Virology Biology

250 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Tan YZ, Aiyer S, Mietzsch M, Hull JA, McKenna R, Grieger J, Samulski RJ, Baker TS, Agbandje-McKenna M, Lyumkis D. Sub-2 Å Ewald curvature corrected structure of an AAV2 capsid variant. Nature Communications. 9: 3628. PMID 30194371 DOI: 10.1038/S41467-018-06076-6  0.56
2018 Xiao W, Gao G, Ling C, Herzog RW, Xiao X, Samulski RJ. Impact of neutralizing antibodies against AAV is a key consideration in gene transfer to nonhuman primates. Nature Medicine. PMID 29867233 DOI: 10.1038/S41591-018-0062-2  0.36
2018 Bennett AD, Wong K, Lewis J, Tseng YS, Smith JK, Chipman P, McKenna R, Samulski RJ, Kleinschmidt J, Agbandje-McKenna M. AAV6 K531 serves a dual function in selective receptor and antibody ADK6 recognition. Virology. 518: 369-376. PMID 29604478 DOI: 10.1016/J.Virol.2018.03.007  0.56
2016 Nicolson SC, Li C, Hirsch ML, Setola V, Samulski RJ. Identification and validation of small molecules that enhance recombinant Adeno-associated virus transduction following high throughput screen. Journal of Virology. PMID 27147738 DOI: 10.1128/Jvi.02953-15  1
2016 Summerford C, Samulski RJ. AAVR: A Multi-Serotype Receptor for AAV. Molecular Therapy : the Journal of the American Society of Gene Therapy. 24: 663-6. PMID 27081719 DOI: 10.1038/mt.2016.49  1
2016 Xiao PJ, Mitchell AM, Huang L, Li C, Samulski RJ. Disruption of Microtubules post Virus Entry Enhances Adeno-Associated Virus Vector Transduction. Human Gene Therapy. PMID 26942476 DOI: 10.1089/Hum.2016.008  1
2016 Wang G, Evans CH, Benson JM, Hutt JA, Seagrave J, Wilder JA, Grieger JC, Samulski RJ, Terse PS. Safety and biodistribution assessment of sc-rAAV2.5IL-1Ra administered via intra-articular injection in a mono-iodoacetate-induced osteoarthritis rat model. Molecular Therapy. Methods & Clinical Development. 3: 15052. PMID 26817025 DOI: 10.1038/Mtm.2015.52  1
2016 Hemphill DD, McIlwraith CW, Slayden RA, Samulski RJ, Goodrich LR. Adeno-associated virus gene therapy vector scAAVIGF-I for transduction of equine articular chondrocytes and RNA-seq analysis Osteoarthritis and Cartilage. 24: 902-911. DOI: 10.1016/J.Joca.2015.12.001  1
2015 Ling C, Wang Y, Lu Y, Wang L, Jayandharan GR, Aslanidi GV, Li B, Cheng B, Ma W, Lentz T, Ling C, Xiao X, Samulski RJ, Muzyczka N, Srivastava A. The Adeno-Associated Virus Genome Packaging Puzzle. Journal of Molecular and Genetic Medicine : An International Journal of Biomedical Research. 9. PMID 26949410 DOI: 10.4172/1747-0862.1000175  1
2015 Grieger JC, Soltys SM, Samulski RJ. Production of Recombinant Adeno-associated Virus Vectors Using Suspension HEK293 Cells and Continuous Harvest of Vector From the Culture Media for GMP FIX and FLT1 Clinical Vector. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 26437810 DOI: 10.1038/Mt.2015.187  1
2015 Ye L, Yu H, Li C, Hirsch ML, Zhang L, Samulski RJ, Li W, Liu Z. Adeno-Associated Virus Vector Mediated Delivery of the HBV Genome Induces Chronic Hepatitis B Virus Infection and Liver Fibrosis in Mice. Plos One. 10: e0130052. PMID 26075890 DOI: 10.1371/journal.pone.0130052  1
2015 Goodrich LR, Grieger JC, Phillips JN, Khan N, Gray SJ, McIlwraith CW, Samulski RJ. scAAVIL-1ra dosing trial in a large animal model and validation of long-term expression with repeat administration for osteoarthritis therapy. Gene Therapy. 22: 536-45. PMID 25902762 DOI: 10.1038/Gt.2015.21  1
2015 Hastie E, Samulski RJ. Adeno-associated virus at 50: a golden anniversary of discovery, research, and gene therapy success--a personal perspective. Human Gene Therapy. 26: 257-65. PMID 25807962 DOI: 10.1089/Hum.2015.025  1
2015 Monahan PE, Sun J, Gui T, Hu G, Hannah WB, Wichlan DG, Wu Z, Grieger JC, Li C, Suwanmanee T, Stafford DW, Booth CJ, Samulski JJ, Kafri T, McPhee SW, ... Samulski RJ, et al. Employing a gain-of-function factor IX variant R338L to advance the efficacy and safety of hemophilia B human gene therapy: preclinical evaluation supporting an ongoing adeno-associated virus clinical trial. Human Gene Therapy. 26: 69-81. PMID 25419787 DOI: 10.1089/Hum.2014.106  1
2015 Johnson-Kerner BL, Ahmad FS, Diaz AG, Greene JP, Gray SJ, Samulski RJ, Chung WK, Van Coster R, Maertens P, Noggle SA, Henderson CE, Wichterle H. Intermediate filament protein accumulation in motor neurons derived from giant axonal neuropathy iPSCs rescued by restoration of gigaxonin. Human Molecular Genetics. 24: 1420-31. PMID 25398950 DOI: 10.1093/Hmg/Ddu556  1
2015 Lentz TB, Samulski RJ. Insight into the mechanism of inhibition of adeno-associated virus by the Mre11/Rad50/Nbs1 complex. Journal of Virology. 89: 181-94. PMID 25320294 DOI: 10.1128/Jvi.01990-14  1
2015 Li C, Wu S, Albright B, Hirsch M, Li W, Tseng YS, Agbandje-McKenna M, McPhee S, Asokan A, Samulski RJ. Development of Patient-specific AAV Vectors After Neutralizing Antibody Selection for Enhanced Muscle Gene Transfer Molecular Therapy. DOI: 10.1038/mt.2015.134  1
2014 Samulski RJ, Muzyczka N. AAV-Mediated Gene Therapy for Research and Therapeutic Purposes. Annual Review of Virology. 1: 427-51. PMID 26958729 DOI: 10.1146/Annurev-Virology-031413-085355  1
2014 Murlidharan G, Samulski RJ, Asokan A. Biology of adeno-associated viral vectors in the central nervous system. Frontiers in Molecular Neuroscience. 7: 76. PMID 25285067 DOI: 10.3389/Fnmol.2014.00076  1
2014 Weinberg MS, Nicolson S, Bhatt AP, McLendon M, Li C, Samulski RJ. Recombinant adeno-associated virus utilizes cell-specific infectious entry mechanisms. Journal of Virology. 88: 12472-84. PMID 25142580 DOI: 10.1128/Jvi.01971-14  1
2014 Hemphill DD, McIlwraith CW, Samulski RJ, Goodrich LR. Adeno-associated viral vectors show serotype specific transduction of equine joint tissue explants and cultured monolayers. Scientific Reports. 4: 5861. PMID 25069854 DOI: 10.1038/srep05861  1
2014 Ishikawa K, Fish KM, Tilemann L, Rapti K, Aguero J, Santos-Gallego CG, Lee A, Karakikes I, Xie C, Akar FG, Shimada YJ, Gwathmey JK, Asokan A, McPhee S, Samulski J, ... Samulski RJ, et al. Cardiac I-1c overexpression with reengineered AAV improves cardiac function in swine ischemic heart failure. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 2038-45. PMID 25023328 DOI: 10.1038/Mt.2014.127  1
2014 Hirsch ML, Samulski RJ. AAV-mediated gene editing via double-strand break repair. Methods in Molecular Biology (Clifton, N.J.). 1114: 291-307. PMID 24557911 DOI: 10.1007/978-1-62703-761-7_19  1
2014 Nicolson SC, Samulski RJ. Recombinant adeno-associated virus utilizes host cell nuclear import machinery to enter the nucleus. Journal of Virology. 88: 4132-44. PMID 24478436 DOI: 10.1128/JVI.02660-13  1
2014 Bartus RT, Weinberg MS, Samulski RJ. Parkinson's disease gene therapy: success by design meets failure by efficacy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 487-97. PMID 24356252 DOI: 10.1038/Mt.2013.281  1
2014 Qiao C, Li C, Zhao C, Li J, Bian T, Grieger J, Li J, Samulski RJ, Xiao X. K137R mutation on adeno-associated viral capsids had minimal effect on enhancing gene delivery in vivo. Human Gene Therapy Methods. 25: 33-9. PMID 24116972 DOI: 10.1089/Hgtb.2013.176  1
2013 Dismuke DJ, Tenenbaum L, Samulski RJ. Biosafety of recombinant adeno-associated virus vectors. Current Gene Therapy. 13: 434-52. PMID 24195602 DOI: 10.2174/15665232113136660007  1
2013 Asokan A, Samulski RJ. An emerging adeno-associated viral vector pipeline for cardiac gene therapy. Human Gene Therapy. 24: 906-13. PMID 24164238 DOI: 10.1089/Hum.2013.2515  1
2013 Mitchell AM, Samulski RJ. Mechanistic insights into the enhancement of adeno-associated virus transduction by proteasome inhibitors. Journal of Virology. 87: 13035-41. PMID 24027330 DOI: 10.1128/Jvi.01826-13  1
2013 Shen S, Horowitz ED, Troupes AN, Brown SM, Pulicherla N, Samulski RJ, Agbandje-McKenna M, Asokan A. Engraftment of a galactose receptor footprint onto adeno-associated viral capsids improves transduction efficiency. The Journal of Biological Chemistry. 288: 28814-23. PMID 23940044 DOI: 10.1074/Jbc.M113.482380  1
2013 Hirsch ML, Li C, Bellon I, Yin C, Chavala S, Pryadkina M, Richard I, Samulski RJ. Oversized AAV transductifon is mediated via a DNA-PKcs-independent, Rad51C-dependent repair pathway. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 2205-16. PMID 23939025 DOI: 10.1038/Mt.2013.184  1
2013 Redmond DE, McEntire CR, Kingsbery JP, Leranth C, Elsworth JD, Bjugstad KB, Roth RH, Samulski RJ, Sladek JR. Comparison of fetal mesencephalic grafts, AAV-delivered GDNF, and both combined in an MPTP-induced nonhuman primate Parkinson's model. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 2160-8. PMID 23913185 DOI: 10.1038/Mt.2013.180  1
2013 Johnson MC, Garland AL, Nicolson SC, Li C, Samulski RJ, Wang B, Tisch R. β-cell-specific IL-2 therapy increases islet Foxp3+Treg and suppresses type 1 diabetes in NOD mice. Diabetes. 62: 3775-84. PMID 23884888 DOI: 10.2337/Db13-0669  1
2013 Dismuke D, Samulski RJ. Hepatic gene therapy using lentiviral vectors: has safety been established? Hepatology (Baltimore, Md.). 58: 13-4. PMID 23695955 DOI: 10.1002/hep.26460  1
2013 Lompré AM, Hadri L, Merlet E, Keuylian Z, Mougenot N, Karakikes I, Chen J, Atassi F, Marchand A, Blaise R, Limon I, McPhee SW, Samulski RJ, Hajjar RJ, Lipskaia L. Efficient transduction of vascular smooth muscle cells with a translational AAV2.5 vector: a new perspective for in-stent restenosis gene therapy. Gene Therapy. 20: 901-12. PMID 23535897 DOI: 10.1038/Gt.2013.13  1
2013 He Y, Weinberg MS, Hirsch M, Johnson MC, Tisch R, Samulski RJ, Li C. Kinetics of adeno-associated virus serotype 2 (AAV2) and AAV8 capsid antigen presentation in vivo are identical. Human Gene Therapy. 24: 545-53. PMID 23534873 DOI: 10.1089/Hum.2013.065  1
2013 O'Reilly M, Kohn DB, Bartlett J, Benson J, Brooks PJ, Byrne BJ, Camozzi C, Cornetta K, Crystal RG, Fong Y, Gargiulo L, Gopal-Srivastava R, High KA, Jacobson SG, Jambou RC, ... ... Samulski RJ, et al. Gene therapy for rare diseases: summary of a National Institutes of Health workshop, September 13, 2012. Human Gene Therapy. 24: 355-62. PMID 23517518 DOI: 10.1089/Hum.2013.064  1
2013 Sinici I, Yonekawa S, Tkachyova I, Gray SJ, Samulski RJ, Wakarchuk W, Mark BL, Mahuran DJ. In cellulo examination of a beta-alpha hybrid construct of beta-hexosaminidase A subunits, reported to interact with the GM2 activator protein and hydrolyze GM2 ganglioside. Plos One. 8: e57908. PMID 23483939 DOI: 10.1371/Journal.Pone.0057908  1
2013 Li C, He Y, Nicolson S, Hirsch M, Weinberg MS, Zhang P, Kafri T, Samulski RJ. Adeno-associated virus capsid antigen presentation is dependent on endosomal escape. The Journal of Clinical Investigation. 123: 1390-401. PMID 23454772 DOI: 10.1172/Jci66611  1
2013 Venkatakrishnan B, Yarbrough J, Domsic J, Bennett A, Bothner B, Kozyreva OG, Samulski RJ, Muzyczka N, McKenna R, Agbandje-McKenna M. Structure and dynamics of adeno-associated virus serotype 1 VP1-unique N-terminal domain and its role in capsid trafficking. Journal of Virology. 87: 4974-84. PMID 23427155 DOI: 10.1128/Jvi.02524-12  1
2013 Goodrich LR, Phillips JN, McIlwraith CW, Foti SB, Grieger JC, Gray SJ, Samulski RJ. Optimization of scAAVIL-1ra In Vitro and In Vivo to Deliver High Levels of Therapeutic Protein for Treatment of Osteoarthritis. Molecular Therapy. Nucleic Acids. 2: e70. PMID 23385523 DOI: 10.1038/Mtna.2012.61  1
2013 Mussche S, Devreese B, Nagabhushan Kalburgi S, Bachaboina L, Fox JC, Shih HJ, Van Coster R, Samulski RJ, Gray SJ. Restoration of cytoskeleton homeostasis after gigaxonin gene transfer for giant axonal neuropathy. Human Gene Therapy. 24: 209-19. PMID 23316953 DOI: 10.1089/Hum.2012.107  1
2013 Fish KM, Ladage D, Kawase Y, Karakikes I, Jeong D, Ly H, Ishikawa K, Hadri L, Tilemann L, Muller-Ehmsen J, Samulski RJ, Kranias EG, Hajjar RJ. AAV9.I-1c delivered via direct coronary infusion in a porcine model of heart failure improves contractility and mitigates adverse remodeling. Circulation. Heart Failure. 6: 310-7. PMID 23271792 DOI: 10.1161/Circheartfailure.112.971325  1
2013 Gadalla KK, Bailey ME, Spike RC, Ross PD, Woodard KT, Kalburgi SN, Bachaboina L, Deng JV, West AE, Samulski RJ, Gray SJ, Cobb SR. Improved survival and reduced phenotypic severity following AAV9/MECP2 gene transfer to neonatal and juvenile male Mecp2 knockout mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 18-30. PMID 23011033 DOI: 10.1038/Mt.2012.200  1
2013 Weinberg MS, Samulski RJ, McCown TJ. Adeno-associated virus (AAV) gene therapy for neurological disease. Neuropharmacology. 69: 82-8. PMID 22465202 DOI: 10.1016/j.neuropharm.2012.03.004  1
2013 Ferreira JR, Hirsch ML, Zhang L, Park Y, Samulski RJ, Hu WS, Ko CC. Three-dimensional multipotent progenitor cell aggregates for expansion, osteogenic differentiation and 'in vivo' tracing with AAV vector serotype 6. Gene Therapy. 20: 158-68. PMID 22402320 DOI: 10.1038/Gt.2012.16  1
2013 Ellis BL, Hirsch ML, Porter SN, Samulski RJ, Porteus MH. Zinc-finger nuclease-mediated gene correction using single AAV vector transduction and enhancement by Food and Drug Administration-approved drugs. Gene Therapy. 20: 35-42. PMID 22257934 DOI: 10.1038/Gt.2011.211  1
2012 Leone P, Shera D, McPhee SW, Francis JS, Kolodny EH, Bilaniuk LT, Wang DJ, Assadi M, Goldfarb O, Goldman HW, Freese A, Young D, During MJ, Samulski RJ, Janson CG. Long-term follow-up after gene therapy for canavan disease. Science Translational Medicine. 4: 165ra163. PMID 23253610 DOI: 10.1126/Scitranslmed.3003454  1
2012 Xiao PJ, Lentz TB, Samulski RJ. Recombinant adeno-associated virus: clinical application and development as a gene-therapy vector. Therapeutic Delivery. 3: 835-56. PMID 22900466 DOI: 10.4155/Tde.12.63  1
2012 Xiao PJ, Samulski RJ. Cytoplasmic trafficking, endosomal escape, and perinuclear accumulation of adeno-associated virus type 2 particles are facilitated by microtubule network. Journal of Virology. 86: 10462-73. PMID 22811523 DOI: 10.1128/Jvi.00935-12  1
2012 Li C, Diprimio N, Bowles DE, Hirsch ML, Monahan PE, Asokan A, Rabinowitz J, Agbandje-McKenna M, Samulski RJ. Single amino acid modification of adeno-associated virus capsid changes transduction and humoral immune profiles. Journal of Virology. 86: 7752-9. PMID 22593151 DOI: 10.1128/Jvi.00675-12  1
2012 Grieger JC, Samulski RJ. Adeno-associated virus vectorology, manufacturing, and clinical applications. Methods in Enzymology. 507: 229-54. PMID 22365777 DOI: 10.1016/B978-0-12-386509-0.00012-0  1
2012 Asokan A, Schaffer DV, Samulski RJ. The AAV vector toolkit: poised at the clinical crossroads. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 699-708. PMID 22273577 DOI: 10.1038/Mt.2011.287  1
2012 Xiao PJ, Li C, Neumann A, Samulski RJ. Quantitative 3D tracing of gene-delivery viral vectors in human cells and animal tissues. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 317-28. PMID 22108857 DOI: 10.1038/mt.2011.250  1
2012 Bowles DE, McPhee SW, Li C, Gray SJ, Samulski JJ, Camp AS, Li J, Wang B, Monahan PE, Rabinowitz JE, Grieger JC, Govindasamy L, Agbandje-McKenna M, Xiao X, Samulski RJ. Phase 1 gene therapy for Duchenne muscular dystrophy using a translational optimized AAV vector. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 443-55. PMID 22068425 DOI: 10.1038/Mt.2011.237  1
2012 Lentz TB, Gray SJ, Samulski RJ. Viral vectors for gene delivery to the central nervous system. Neurobiology of Disease. 48: 179-88. PMID 22001604 DOI: 10.1016/J.Nbd.2011.09.014  1
2012 Federici T, Taub JS, Baum GR, Gray SJ, Grieger JC, Matthews KA, Handy CR, Passini MA, Samulski RJ, Boulis NM. Robust spinal motor neuron transduction following intrathecal delivery of AAV9 in pigs. Gene Therapy. 19: 852-9. PMID 21918551 DOI: 10.1038/Gt.2011.130  1
2012 Li C, Narkbunnam N, Samulski RJ, Asokan A, Hu G, Jacobson LJ, Manco-Johnson MJ, Monahan PE. Neutralizing antibodies against adeno-associated virus examined prospectively in pediatric patients with hemophilia. Gene Therapy. 19: 288-94. PMID 21697954 DOI: 10.1038/Gt.2011.90  1
2011 Hirsch ML, Fagan BM, Dumitru R, Bower JJ, Yadav S, Porteus MH, Pevny LH, Samulski RJ. Viral single-strand DNA induces p53-dependent apoptosis in human embryonic stem cells. Plos One. 6: e27520. PMID 22114676 DOI: 10.1371/Journal.Pone.0027520  1
2011 Gray SJ, Choi VW, Asokan A, Haberman RA, McCown TJ, Samulski RJ. Production of recombinant adeno-associated viral vectors and use in in vitro and in vivo administration. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 4.17. PMID 21971848 DOI: 10.1002/0471142301.Ns0417S57  1
2011 Li C, Xiao P, Gray SJ, Weinberg MS, Samulski RJ. Combination therapy utilizing shRNA knockdown and an optimized resistant transgene for rescue of diseases caused by misfolded proteins. Proceedings of the National Academy of Sciences of the United States of America. 108: 14258-63. PMID 21844342 DOI: 10.1073/Pnas.1109522108  1
2011 Li W, Zhang L, Wu Z, Pickles RJ, Samulski RJ. AAV-6 mediated efficient transduction of mouse lower airways. Virology. 417: 327-33. PMID 21752418 DOI: 10.1016/J.Virol.2011.06.009  1
2011 Usui S, Oveson BC, Iwase T, Lu L, Lee SY, Jo YJ, Wu Z, Choi EY, Samulski RJ, Campochiaro PA. Overexpression of SOD in retina: need for increase in H2O2-detoxifying enzyme in same cellular compartment. Free Radical Biology & Medicine. 51: 1347-54. PMID 21736939 DOI: 10.1016/J.Freeradbiomed.2011.06.010  1
2011 Johnson JS, Gentzsch M, Zhang L, Ribeiro CM, Kantor B, Kafri T, Pickles RJ, Samulski RJ. AAV exploits subcellular stress associated with inflammation, endoplasmic reticulum expansion, and misfolded proteins in models of cystic fibrosis. Plos Pathogens. 7: e1002053. PMID 21625534 DOI: 10.1371/Journal.Ppat.1002053  1
2011 Weinberg MS, Blake BL, Samulski RJ, McCown TJ. The influence of epileptic neuropathology and prior peripheral immunity on CNS transduction by rAAV2 and rAAV5. Gene Therapy. 18: 961-8. PMID 21490684 DOI: 10.1038/Gt.2011.49  1
2011 Gray SJ, Matagne V, Bachaboina L, Yadav S, Ojeda SR, Samulski RJ. Preclinical differences of intravascular AAV9 delivery to neurons and glia: a comparative study of adult mice and nonhuman primates. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1058-69. PMID 21487395 DOI: 10.1038/Mt.2011.72  1
2011 Gray SJ, Foti SB, Schwartz JW, Bachaboina L, Taylor-Blake B, Coleman J, Ehlers MD, Zylka MJ, McCown TJ, Samulski RJ. Optimizing promoters for recombinant adeno-associated virus-mediated gene expression in the peripheral and central nervous system using self-complementary vectors. Human Gene Therapy. 22: 1143-53. PMID 21476867 DOI: 10.1089/Hum.2010.245  1
2011 Goudy KS, Johnson MC, Garland A, Li C, Samulski RJ, Wang B, Tisch R. Reduced IL-2 expression in NOD mice leads to a temporal increase in CD62Llo FoxP3+ CD4+ T cells with limited suppressor activity. European Journal of Immunology. 41: 1480-90. PMID 21469091 DOI: 10.1002/Eji.201040890  1
2011 Snyder BR, Gray SJ, Quach ET, Huang JW, Leung CH, Samulski RJ, Boulis NM, Federici T. Comparison of adeno-associated viral vector serotypes for spinal cord and motor neuron gene delivery. Human Gene Therapy. 22: 1129-35. PMID 21443428 DOI: 10.1089/Hum.2011.008  1
2011 Goudy KS, Johnson MC, Garland A, Li C, Samulski RJ, Wang B, Tisch R. Inducible adeno-associated virus-mediated IL-2 gene therapy prevents autoimmune diabetes. Journal of Immunology (Baltimore, Md. : 1950). 186: 3779-86. PMID 21317396 DOI: 10.4049/Jimmunol.1001422  1
2011 Yazici C, Takahata M, Reynolds DG, Xie C, Samulski RJ, Samulski J, Beecham EJ, Gertzman AA, Spilker M, Zhang X, O'Keefe RJ, Awad HA, Schwarz EM. Self-complementary AAV2.5-BMP2-coated femoral allografts mediated superior bone healing versus live autografts in mice with equivalent biomechanics to unfractured femur. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1416-25. PMID 21206485 DOI: 10.1038/Mt.2010.294  1
2011 Phillips JL, Hegge J, Wolff JA, Samulski RJ, Asokan A. Systemic gene transfer to skeletal muscle using reengineered AAV vectors. Methods in Molecular Biology (Clifton, N.J.). 709: 141-51. PMID 21194026 DOI: 10.1007/978-1-61737-982-6_9  1
2010 Gray SJ, Woodard KT, Samulski RJ. Viral vectors and delivery strategies for CNS gene therapy. Therapeutic Delivery. 1: 517-34. PMID 22833965 DOI: 10.4155/Tde.10.50  1
2010 Mendell JR, Campbell K, Rodino-Klapac L, Sahenk Z, Shilling C, Lewis S, Bowles D, Gray S, Li C, Galloway G, Malik V, Coley B, Clark KR, Li J, Xiao X, ... ... Samulski RJ, et al. Dystrophin immunity in Duchenne's muscular dystrophy. The New England Journal of Medicine. 363: 1429-37. PMID 20925545 DOI: 10.1056/Nejmoa1000228  1
2010 DiPrimio N, McPhee SW, Samulski RJ. Adeno-associated virus for the treatment of muscle diseases: toward clinical trials. Current Opinion in Molecular Therapeutics. 12: 553-60. PMID 20886387  1
2010 Ng R, Govindasamy L, Gurda BL, McKenna R, Kozyreva OG, Samulski RJ, Parent KN, Baker TS, Agbandje-McKenna M. Structural characterization of the dual glycan binding adeno-associated virus serotype 6. Journal of Virology. 84: 12945-57. PMID 20861247 DOI: 10.1128/Jvi.01235-10  1
2010 Mitchell AM, Nicolson SC, Warischalk JK, Samulski RJ. AAV's anatomy: roadmap for optimizing vectors for translational success. Current Gene Therapy. 10: 319-40. PMID 20712583 DOI: 10.2174/156652310793180706  1
2010 Monahan PE, Lothrop CD, Sun J, Hirsch ML, Kafri T, Kantor B, Sarkar R, Tillson DM, Elia JR, Samulski RJ. Proteasome inhibitors enhance gene delivery by AAV virus vectors expressing large genomes in hemophilia mouse and dog models: a strategy for broad clinical application. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1907-16. PMID 20700109 DOI: 10.1038/Mt.2010.170  1
2010 Johnson JS, Li C, DiPrimio N, Weinberg MS, McCown TJ, Samulski RJ. Mutagenesis of adeno-associated virus type 2 capsid protein VP1 uncovers new roles for basic amino acids in trafficking and cell-specific transduction. Journal of Virology. 84: 8888-902. PMID 20573820 DOI: 10.1128/Jvi.00687-10  1
2010 Hollis ER, Jamshidi P, Lorenzana AO, Lee JK, Gray SJ, Samulski RJ, Zheng B, Tuszynski MH. Transient demyelination increases the efficiency of retrograde AAV transduction. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1496-500. PMID 20502445 DOI: 10.1038/Mt.2010.97  1
2010 Lock M, McGorray S, Auricchio A, Ayuso E, Beecham EJ, Blouin-Tavel V, Bosch F, Bose M, Byrne BJ, Caton T, Chiorini JA, Chtarto A, Clark KR, Conlon T, Darmon C, ... ... Samulski RJ, et al. Characterization of a recombinant adeno-associated virus type 2 Reference Standard Material. Human Gene Therapy. 21: 1273-85. PMID 20486768 DOI: 10.1089/Hum.2009.223  1
2010 Hirsch ML, Green L, Porteus MH, Samulski RJ. Self-complementary AAV mediates gene targeting and enhances endonuclease delivery for double-strand break repair. Gene Therapy. 17: 1175-80. PMID 20463753 DOI: 10.1038/Gt.2010.65  1
2010 Hewitt FC, Samulski RJ. Creating a novel origin of replication through modulating DNA-protein interfaces. Plos One. 5: e8850. PMID 20107513 DOI: 10.1371/journal.pone.0008850  0.56
2010 Hirsch ML, Agbandje-McKenna M, Samulski RJ. Little vector, big gene transduction: fragmented genome reassembly of adeno-associated virus. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 6-8. PMID 20048740 DOI: 10.1038/Mt.2009.280  1
2010 Gray SJ, Blake BL, Criswell HE, Nicolson SC, Samulski RJ, McCown TJ, Li W. Directed evolution of a novel adeno-associated virus (AAV) vector that crosses the seizure-compromised blood-brain barrier (BBB). Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 570-8. PMID 20040913 DOI: 10.1038/Mt.2009.292  1
2010 Asokan A, Conway JC, Phillips JL, Li C, Hegge J, Sinnott R, Yadav S, DiPrimio N, Nam HJ, Agbandje-McKenna M, McPhee S, Wolff J, Samulski RJ. Reengineering a receptor footprint of adeno-associated virus enables selective and systemic gene transfer to muscle. Nature Biotechnology. 28: 79-82. PMID 20037580 DOI: 10.1038/Nbt.1599  1
2010 Markakis EA, Vives KP, Bober J, Leichtle S, Leranth C, Beecham J, Elsworth JD, Roth RH, Samulski RJ, Redmond DE. Comparative transduction efficiency of AAV vector serotypes 1-6 in the substantia nigra and striatum of the primate brain. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 588-93. PMID 20010918 DOI: 10.1038/Mt.2009.286  1
2010 Buie LK, Rasmussen CA, Porterfield EC, Ramgolam VS, Choi VW, Markovic-Plese S, Samulski RJ, Kaufman PL, Borrás T. Self-complementary AAV virus (scAAV) safe and long-term gene transfer in the trabecular meshwork of living rats and monkeys. Investigative Ophthalmology & Visual Science. 51: 236-48. PMID 19684004 DOI: 10.1167/Iovs.09-3847  1
2010 Choi VW, Samulski RJ. Gene therapy Vogel and Motulsky's Human Genetics: Problems and Approaches (Fourth Edition). 867-874. DOI: 10.1007/978-3-540-37654-5_40  1
2010 Li C, Hirsch ML, Samulski RJ. Development of AAV vectors for the therapy of autoimmune and inflammatory diseases Milestones in Drug Therapy. 161-180.  1
2009 Hirsch ML, Storici F, Li C, Choi VW, Samulski RJ. AAV recombineering with single strand oligonucleotides. Plos One. 4: e7705. PMID 19888330 DOI: 10.1371/Journal.Pone.0007705  1
2009 Foti SB, Samulski RJ, McCown TJ. Delivering multiple gene products in the brain from a single adeno-associated virus vector. Gene Therapy. 16: 1314-9. PMID 19727140 DOI: 10.1038/Gt.2009.106  1
2009 Goodrich LR, Choi VW, Carbone BA, McIlwraith CW, Samulski RJ. Ex vivo serotype-specific transduction of equine joint tissue by self-complementary adeno-associated viral vectors. Human Gene Therapy. 20: 1697-702. PMID 19642864 DOI: 10.1089/Hum.2009.030  1
2009 Li W, Zhang L, Johnson JS, Zhijian W, Grieger JC, Ping-Jie X, Drouin LM, Agbandje-McKenna M, Pickles RJ, Samulski RJ. Generation of novel AAV variants by directed evolution for improved CFTR delivery to human ciliated airway epithelium. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 2067-77. PMID 19603002 DOI: 10.1038/Mt.2009.155  1
2009 Frank KM, Hogarth DK, Miller JL, Mandal S, Mease PJ, Samulski RJ, Weisgerber GA, Hart J. Investigation of the cause of death in a gene-therapy trial. The New England Journal of Medicine. 361: 161-9. PMID 19587341 DOI: 10.1056/Nejmoa0801066  1
2009 Li C, Goudy K, Hirsch M, Asokan A, Fan Y, Alexander J, Sun J, Monahan P, Seiber D, Sidney J, Sette A, Tisch R, Frelinger J, Samulski RJ. Cellular immune response to cryptic epitopes during therapeutic gene transfer. Proceedings of the National Academy of Sciences of the United States of America. 106: 10770-4. PMID 19541644 DOI: 10.1073/Pnas.0902269106  1
2009 McPhee SWJ, Samulski RJ. Gene therapy for cardiomyocytes, a heart beat away Gene Therapy. 16: 707-708. PMID 19404321 DOI: 10.1038/Gt.2009.40  1
2009 Redmond DE, Elsworth JD, Roth RH, Leranth C, Collier TJ, Blanchard B, Bjugstad KB, Samulski RJ, Aebischer P, Sladek JR. Embryonic substantia nigra grafts in the mesencephalon send neurites to the host striatum in non-human primate after overexpression of GDNF. The Journal of Comparative Neurology. 515: 31-40. PMID 19399891 DOI: 10.1002/Cne.22028  1
2009 Li C, Hirsch M, DiPrimio N, Asokan A, Goudy K, Tisch R, Samulski RJ. Cytotoxic-T-lymphocyte-mediated elimination of target cells transduced with engineered adeno-associated virus type 2 vector in vivo. Journal of Virology. 83: 6817-24. PMID 19369348 DOI: 10.1128/Jvi.00278-09  0.64
2009 Hewitt FC, Li C, Gray SJ, Cockrell S, Washburn M, Samulski RJ. Reducing the risk of adeno-associated virus (AAV) vector mobilization with AAV type 5 vectors. Journal of Virology. 83: 3919-29. PMID 19211760 DOI: 10.1128/Jvi.02466-08  1
2009 Johnson JS, Samulski RJ. Enhancement of adeno-associated virus infection by mobilizing capsids into and out of the nucleolus. Journal of Virology. 83: 2632-44. PMID 19109385 DOI: 10.1128/Jvi.02309-08  1
2009 Li C, Hirsch M, Carter P, Asokan A, Zhou X, Wu Z, Samulski RJ. A small regulatory element from chromosome 19 enhances liver-specific gene expression. Gene Therapy. 16: 43-51. PMID 18701910 DOI: 10.1038/Gt.2008.134  1
2008 Li W, Asokan A, Wu Z, Van Dyke T, DiPrimio N, Johnson JS, Govindaswamy L, Agbandje-McKenna M, Leichtle S, Eugene Redmond D, McCown TJ, Petermann KB, Sharpless NE, Samulski RJ. Engineering and Selection of Shuffled AAV Genomes: A New Strategy for Producing Targeted Biological Nanoparticles. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1252-1260. PMID 28178482 DOI: 10.1038/Mt.2008.100  0.8
2008 Sun J, Hakobyan N, Valentino LA, Feldman BL, Samulski RJ, Monahan PE. Intraarticular factor IX protein or gene replacement protects against development of hemophilic synovitis in the absence of circulating factor IX. Blood. 112: 4532-41. PMID 18716130 DOI: 10.1182/blood-2008-01-131417  1
2008 Asokan A, Johnson JS, Li C, Samulski RJ. Bioluminescent virion shells: new tools for quantitation of AAV vector dynamics in cells and live animals. Gene Therapy. 15: 1618-22. PMID 18668144 DOI: 10.1038/Gt.2008.127  1
2008 Yazici C, Yanoso L, Xie C, Reynolds DG, Samulski RJ, Samulski J, Yannariello-Brown J, Gertzman AA, Zhang X, Awad HA, Schwarz EM. The effect of surface demineralization of cortical bone allograft on the properties of recombinant adeno-associated virus coatings. Biomaterials. 29: 3882-7. PMID 18590929 DOI: 10.1016/J.Biomaterials.2008.06.007  1
2008 Gray SJ, Samulski RJ. Optimizing gene delivery vectors for the treatment of heart disease. Expert Opinion On Biological Therapy. 8: 911-22. PMID 18549322 DOI: 10.1517/14712598.8.7.911  1
2008 Li W, Asokan A, Wu Z, Van Dyke T, DiPrimio N, Johnson JS, Govindaswamy L, Agbandje-McKenna M, Leichtle S, Redmond DE, McCown TJ, Petermann KB, Sharpless NE, Samulski RJ. Engineering and selection of shuffled AAV genomes: a new strategy for producing targeted biological nanoparticles. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1252-60. PMID 18500254 DOI: 10.1038/mt.2008.100  1
2008 DiPrimio N, Asokan A, Govindasamy L, Agbandje-McKenna M, Samulski RJ. Surface loop dynamics in adeno-associated virus capsid assembly. Journal of Virology. 82: 5178-89. PMID 18367523 DOI: 10.1128/Jvi.02721-07  1
2008 Elsworth JD, Redmond DE, Leranth C, Bjugstad KB, Sladek JR, Collier TJ, Foti SB, Samulski RJ, Vives KP, Roth RH. AAV2-mediated gene transfer of GDNF to the striatum of MPTP monkeys enhances the survival and outgrowth of co-implanted fetal dopamine neurons. Experimental Neurology. 211: 252-8. PMID 18346734 DOI: 10.1016/J.Expneurol.2008.01.026  1
2008 Hollis ER, Kadoya K, Hirsch M, Samulski RJ, Tuszynski MH. Efficient retrograde neuronal transduction utilizing self-complementary AAV1. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 296-301. PMID 18223548 DOI: 10.1038/  1
2008 Zhou X, Zeng X, Fan Z, Li C, McCown T, Samulski RJ, Xiao X. Adeno-associated virus of a single-polarity DNA genome is capable of transduction in vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 494-9. PMID 18180769 DOI: 10.1038/Sj.Mt.6300397  1
2008 Zhong L, Zhou X, Li Y, Qing K, Xiao X, Samulski RJ, Srivastava A. Single-polarity recombinant adeno-associated virus 2 vector-mediated transgene expression in vitro and in vivo: mechanism of transduction. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 290-5. PMID 18087261 DOI: 10.1038/Sj.Mt.6300376  1
2008 Lyon AR, Sato M, Hajjar RJ, Samulski RJ, Harding SE. Gene therapy: Targeting the myocardium Heart. 94: 89-99. PMID 18083952 DOI: 10.1136/Hrt.2007.116483  1
2008 Wu Z, Sun J, Zhang T, Yin C, Yin F, Van Dyke T, Samulski RJ, Monahan PE. Optimization of self-complementary AAV vectors for liver-directed expression results in sustained correction of hemophilia B at low vector dose. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 280-9. PMID 18059373 DOI: 10.1038/Sj.Mt.6300355  1
2007 Choi VW, Asokan A, Haberman RA, Samulski RJ. Production of recombinant adeno-associated viral vectors. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. Unit 12.9. PMID 18428408 DOI: 10.1002/0471142905.Hg1209S53  1
2007 Choi VW, Asokan A, Haberman RA, Samulski RJ. Production of recombinant adeno-associated viral vectors for in vitro and in vivo use. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit 16.25. PMID 18265393 DOI: 10.1002/0471142727.Mb1625S78  1
2007 Foti S, Haberman RP, Samulski RJ, McCown TJ. Adeno-associated virus-mediated expression and constitutive secretion of NPY or NPY13-36 suppresses seizure activity in vivo. Gene Therapy. 14: 1534-6. PMID 17713567 DOI: 10.1038/Sj.Gt.3303013  1
2007 Wang J, Xie J, Lu H, Chen L, Hauck B, Samulski RJ, Xiao W. Existence of transient functional double-stranded DNA intermediates during recombinant AAV transduction. Proceedings of the National Academy of Sciences of the United States of America. 104: 13104-9. PMID 17664425 DOI: 10.1073/Pnas.0702778104  1
2007 Yokoi K, Kachi S, Zhang HS, Gregory PD, Spratt SK, Samulski RJ, Campochiaro PA. Ocular gene transfer with self-complementary AAV vectors. Investigative Ophthalmology & Visual Science. 48: 3324-8. PMID 17591905 DOI: 10.1167/iovs.06-1306  1
2007 Grieger JC, Johnson JS, Gurda-Whitaker B, Agbandje-McKenna M, Samulski RJ. Surface-exposed adeno-associated virus Vp1-NLS capsid fusion protein rescues infectivity of noninfectious wild-type Vp2/Vp3 and Vp3-only capsids but not that of fivefold pore mutant virions. Journal of Virology. 81: 7833-43. PMID 17507473 DOI: 10.1128/Jvi.00580-07  1
2007 Li C, Hirsch M, Asokan A, Zeithaml B, Ma H, Kafri T, Samulski RJ. Adeno-associated virus type 2 (AAV2) capsid-specific cytotoxic T lymphocytes eliminate only vector-transduced cells coexpressing the AAV2 capsid in vivo. Journal of Virology. 81: 7540-7. PMID 17475652 DOI: 10.1128/Jvi.00529-07  1
2007 Maynor BW, LaRue I, Hu Z, Rolland JP, Pandya A, Fu Q, Liu J, Spontak RJ, Sheiko SS, Samulski RJ, Samulski ET, DeSimone JM. Supramolecular nanomimetics: replication of micelles, viruses, and other naturally occurring nanoscale objects. Small (Weinheim An Der Bergstrasse, Germany). 3: 845-9. PMID 17393549 DOI: 10.1002/Smll.200600507  1
2006 Choi VW, Asokan A, Haberman RA, McCown TJ, Samulski RJ. Production of recombinant adeno-associated viral vectors and use for in vitro and in vivo administration. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 4.17. PMID 18428636 DOI: 10.1002/0471142301.ns0417s35  1
2006 Grieger JC, Choi VW, Samulski RJ. Production and characterization of adeno-associated viral vectors. Nature Protocols. 1: 1412-28. PMID 17406430 DOI: 10.1038/Nprot.2006.207  1
2006 Hajjar RJ, Samulski RJ. Heart failure: A silver bullet to treat heart failure Gene Therapy. 13: 997. PMID 17262904 DOI: 10.1038/Sj.Gt.3302747  1
2006 Choi VW, McCarty DM, Samulski RJ. Host cell DNA repair pathways in adeno-associated viral genome processing. Journal of Virology. 80: 10346-56. PMID 17041215 DOI: 10.1128/Jvi.00841-06  1
2006 Wu Z, Asokan A, Grieger JC, Govindasamy L, Agbandje-McKenna M, Samulski RJ. Single amino acid changes can influence titer, heparin binding, and tissue tropism in different adeno-associated virus serotypes. Journal of Virology. 80: 11393-7. PMID 16943302 DOI: 10.1128/Jvi.01288-06  1
2006 Wu Z, Miller E, Agbandje-McKenna M, Samulski RJ. Alpha2,3 and alpha2,6 N-linked sialic acids facilitate efficient binding and transduction by adeno-associated virus types 1 and 6. Journal of Virology. 80: 9093-103. PMID 16940521 DOI: 10.1128/Jvi.00895-06  1
2006 Asokan A, Hamra JB, Govindasamy L, Agbandje-McKenna M, Samulski RJ. Adeno-associated virus type 2 contains an integrin alpha5beta1 binding domain essential for viral cell entry. Journal of Virology. 80: 8961-9. PMID 16940508 DOI: 10.1128/Jvi.00843-06  1
2006 Wu Z, Asokan A, Samulski RJ. Adeno-associated virus serotypes: vector toolkit for human gene therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 316-27. PMID 16824801 DOI: 10.1016/J.Ymthe.2006.05.009  1
2006 Grieger JC, Snowdy S, Samulski RJ. Separate basic region motifs within the adeno-associated virus capsid proteins are essential for infectivity and assembly. Journal of Virology. 80: 5199-210. PMID 16699000 DOI: 10.1128/Jvi.02723-05  1
2006 Lehmann TG, Luedde T, Schwabe RF, Bunzendahl H, Samulski RJ, Lemasters JJ, Brenner DA. Minimizing oxidative stress by gene delivery of superoxide dismutase accelerates regeneration after transplantation of reduced-size livers in the rat. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. 12: 550-9. PMID 16555330 DOI: 10.1002/Lt.20632  1
2006 Borrás T, Xue W, Choi VW, Bartlett JS, Li G, Samulski RJ, Chisolm SS. Mechanisms of AAV transduction in glaucoma-associated human trabecular meshwork cells. The Journal of Gene Medicine. 8: 589-602. PMID 16506246 DOI: 10.1002/Jgm.886  1
2006 Asokan A, Samulski RJ. AAV does the shuffle. Nature Biotechnology. 24: 158-60. PMID 16465157 DOI: 10.1038/Nbt0206-158  1
2006 Camp AS, McPhee SW, Samulski RJ. Novel Approaches for Production of Recombinant Adeno-Associated Virus Cell Biology, Four-Volume Set. 1: 457-461. DOI: 10.1016/B978-012164730-8/50056-3  1
2005 Grieger JC, Samulski RJ. Adeno-associated virus as a gene therapy vector: vector development, production and clinical applications. Advances in Biochemical Engineering/Biotechnology. 99: 119-45. PMID 16568890 DOI: 10.1007/10_005  1
2005 Grieger JC, Samulski RJ. Packaging capacity of adeno-associated virus serotypes: impact of larger genomes on infectivity and postentry steps. Journal of Virology. 79: 9933-44. PMID 16014954 DOI: 10.1128/Jvi.79.15.9933-9944.2005  1
2005 Choi VW, McCarty DM, Samulski RJ. AAV hybrid serotypes: improved vectors for gene delivery. Current Gene Therapy. 5: 299-310. PMID 15975007 DOI: 10.2174/1566523054064968  1
2005 Li C, Bowles DE, Van Dyke T, Samulski RJ. Adeno-associated virus vectors: Potential applications for cancer gene therapy Cancer Gene Therapy. 12: 913-925. PMID 15962012 DOI: 10.1038/Sj.Cgt.7700876  1
2005 Hacker UT, Wingenfeld L, Kofler DM, Schuhmann NK, Lutz S, Herold T, King SB, Gerner FM, Perabo L, Rabinowitz J, McCarty DM, Samulski RJ, Hallek M, Büning H. Adeno-associated virus serotypes 1 to 5 mediated tumor cell directed gene transfer and improvement of transduction efficiency. The Journal of Gene Medicine. 7: 1429-38. PMID 15945124 DOI: 10.1002/Jgm.782  1
2005 Asokan A, Samulski RJ. From crystal structure to clinic: highlights of the Tenth International Parvovirus Workshop. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 656-60. PMID 15892211 DOI: 10.1016/J.Ymthe.2005.03.014  1
2005 Choi VW, Samulski RJ, McCarty DM. Effects of adeno-associated virus DNA hairpin structure on recombination. Journal of Virology. 79: 6801-7. PMID 15890919 DOI: 10.1128/Jvi.79.11.6801-6807.2005  1
2005 Li C, Samulski RJ. Serotype-specific replicating AAV helper constructs increase recombinant AAV type 2 vector production. Virology. 335: 10-21. PMID 15823602 DOI: 10.1016/j.virol.2005.02.008  1
2005 Xu D, McCarty D, Fernandes A, Fisher M, Samulski RJ, Juliano RL. Delivery of MDR1 small interfering RNA by self-complementary recombinant adeno-associated virus vector Molecular Therapy. 11: 523-530. PMID 15771955 DOI: 10.1016/J.Ymthe.2004.12.019  1
2005 Chen S, Kapturczak M, Loiler SA, Zolotukhin S, Glushakova OY, Madsen KM, Samulski RJ, Hauswirth WW, Campbell-Thompson M, Berns KI, Flotte TR, Atkinson MA, Tisher CC, Agarwal A. Efficient transduction of vascular endothelial cells with recombinant adeno-associated virus serotype 1 and 5 vectors. Human Gene Therapy. 16: 235-47. PMID 15761263 DOI: 10.1089/Hum.2005.16.235  1
2005 Flierl A, Chen Y, Coskun PE, Samulski RJ, Wallace DC. Adeno-associated virus-mediated gene transfer of the heart/muscle adenine nucleotide translocator (ANT) in mouse Gene Therapy. 12: 570-578. PMID 15647764 DOI: 10.1038/Sj.Gt.3302443  1
2005 Suwanmanee T, Choi VW, Samulski RJ, Kafri T, Kole R. 343. Repair of Thalassemic |[beta]|-Globin pre-mRNA by Antisense AAV and Lentiviral Vectors in Cell Culture Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.346  0.6
2005 Choi VW, McCarty DM, Samulski RJ. 18. Facilitation of AAV Genome Circularization by Host Cell Factors Involved in DNA Replication and Double-Strand Break Repair Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.021  0.6
2004 McCarty DM, Young SM, Samulski RJ. Integration of adeno-associated virus (AAV) and recombinant AAV vectors. Annual Review of Genetics. 38: 819-45. PMID 15568995 DOI: 10.1146/annurev.genet.37.110801.143717  1
2004 Du L, Kido M, Lee DV, Rabinowitz JE, Samulski RJ, Jamieson SW, Weitzman MD, Thistlethwaite PA. Differential myocardial gene delivery by recombinant serotype-specific adeno-associated viral vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 10: 604-8. PMID 15336660 DOI: 10.1016/j.ymthe.2004.06.110  1
2004 Negishi A, Chen J, McCarty DM, Samulski RJ, Liu J, Superfine R. Analysis of the interaction between adeno-associated virus and heparan sulfate using atomic force microscopy. Glycobiology. 14: 969-77. PMID 15215232 DOI: 10.1093/Glycob/Cwh118  1
2004 Rabinowitz JE, Bowles DE, Faust SM, Ledford JG, Cunningham SE, Samulski RJ. Cross-dressing the virion: the transcapsidation of adeno-associated virus serotypes functionally defines subgroups. Journal of Virology. 78: 4421-32. PMID 15078923 DOI: 10.1128/Jvi.78.9.4421-4432.2004  1
2004 Chenuaud P, Larcher T, Rabinowitz JE, Provost N, Joussemet B, Bujard H, Samulski RJ, Favre D, Moullier P. Optimal design of a single recombinant adeno-associated virus derived from serotypes 1 and 2 to achieve more tightly regulated transgene expression from nonhuman primate muscle. Molecular Therapy : the Journal of the American Society of Gene Therapy. 9: 410-8. PMID 15006608 DOI: 10.1016/J.Ymthe.2003.12.015  0.4
2004 Stilwell JL, Samulski RJ. Role of viral vectors and virion shells in cellular gene expression. Molecular Therapy : the Journal of the American Society of Gene Therapy. 9: 337-46. PMID 15006600 DOI: 10.1016/J.Ymthe.2003.11.007  1
2004 Chenuaud P, Larcher T, Rabinowitz JE, Provost N, Cherel Y, Casadevall N, Samulski RJ, Moullier P. Autoimmune anemia in macaques following erythropoietin gene therapy. Blood. 103: 3303-4. PMID 14739218 DOI: 10.1182/Blood-2003-11-3845  1
2004 Allen NA, Samulski RJ. The pros and cons of using the mechanism of AAV site-specific recombination in gene delivery Gene Therapy and Regulation. 2: 121-138. DOI: 10.1163/156855803322664619  1
2004 Grieger JC, Rabinowitz JE, Bowles DE, Samulski RJ. 17. Role of Vp2 in AAV Packaging Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.05.098  1
2003 Fu H, Muenzer J, Samulski RJ, Breese G, Sifford J, Zeng X, McCarty DM. Self-complementary adeno-associated virus serotype 2 vector: global distribution and broad dispersion of AAV-mediated transgene expression in mouse brain. Molecular Therapy : the Journal of the American Society of Gene Therapy. 8: 911-7. PMID 14664793 DOI: 10.1016/J.Ymthe.2003.08.021  1
2003 McCarty DM, Fu H, Monahan PE, Toulson CE, Naik P, Samulski RJ. Adeno-associated virus terminal repeat (TR) mutant generates self-complementary vectors to overcome the rate-limiting step to transduction in vivo. Gene Therapy. 10: 2112-8. PMID 14625565 DOI: 10.1038/Sj.Gt.3302134  1
2003 Stilwell JL, McCarty DM, Negishi A, Superfine R, Samulski RJ. Development and characterization of novel empty adenovirus capsids and their impact on cellular gene expression. Journal of Virology. 77: 12881-5. PMID 14610209 DOI: 10.1128/Jvi.77.23.12881-12885.2003  1
2003 Haberman RP, Samulski RJ, McCown TJ. Attenuation of seizures and neuronal death by adeno-associated virus vector galanin expression and secretion. Nature Medicine. 9: 1076-80. PMID 12858168 DOI: 10.1038/nm901  1
2003 Stilwell JL, Samulski RJ. Adeno-associated virus vectors for therapeutic gene transfer. Biotechniques. 34: 148-50, 152, 154 pas. PMID 12545552 DOI: 10.2144/03341Dd01  1
2003 Weitzman MD, Young SM, Cathomen T, Samulski RJ. Targeted integration by adeno-associated virus. Methods in Molecular Medicine. 76: 201-19. PMID 12526165 DOI: 10.1385/1-59259-304-6:201  1
2003 Amiss TJ, McCarty DM, Skulimowski A, Samulski RJ. Identification and characterization of an adeno-associated virus integration site in CV-1 cells from the African green monkey. Journal of Virology. 77: 1904-15. PMID 12525625 DOI: 10.1128/Jvi.77.3.1904-1915.2003  1
2003 Bowles DE, Rabinowitz JE, Samulski RJ. Marker rescue of adeno-associated virus (AAV) capsid mutants: A novel approach for chimeric AAV production Journal of Virology. 77: 423-432. PMID 12477847 DOI: 10.1128/JVI.77.1.423-432.2003  1
2002 McAllister K, Sazani P, Adam M, Cho MJ, Rubinstein M, Samulski RJ, DeSimone JM. Polymeric nanogels produced via inverse microemulsion polymerization as potential gene and antisense delivery agents. Journal of the American Chemical Society. 124: 15198-207. PMID 12487595 DOI: 10.1021/Ja027759Q  1
2002 Rabinowitz JE, Samulski RJ. Crystal-clear view Gene Therapy. 9: 1413-1414. PMID 12378402 DOI: 10.1038/  1
2002 Haberman R, Criswell H, Snowdy S, Ming Z, Breese G, Samulski R, McCown T. Therapeutic liabilities of in vivo viral vector tropism: adeno-associated virus vectors, NMDAR1 antisense, and focal seizure sensitivity. Molecular Therapy : the Journal of the American Society of Gene Therapy. 6: 495-500. PMID 12377191 DOI: 10.1006/Mthe.2002.0701  1
2002 Rabinowitz JE, Samulski RJ. The adeno-associated virus crystal: Impact inversely proportional to size Molecular Therapy. 6: 443-445. PMID 12377184 DOI: 10.1006/mthe.2002.0704  1
2002 Fu H, Samulski RJ, McCown TJ, Picornell YJ, Fletcher D, Muenzer J. Neurological correction of lysosomal storage in a mucopolysaccharidosis IIIB mouse model by adeno-associated virus-mediated gene delivery. Molecular Therapy : the Journal of the American Society of Gene Therapy. 5: 42-9. PMID 11786044 DOI: 10.1006/Mthe.2001.0514  1
2002 Rabinowitz JE, Rolling F, Li C, Conrath H, Xiao W, Xiao X, Samulski RJ. Cross-packaging of a single adeno-associated virus (AAV) type 2 vector genome into multiple AAV serotypes enables transduction with broad specificity. Journal of Virology. 76: 791-801. PMID 11752169 DOI: 10.1128/Jvi.76.2.791-801.2002  1
2001 Wheeler MD, Katuna M, Smutney OM, Froh M, Dikalova A, Mason RP, Samulski RJ, Thurman RG. Comparison of the effect of adenoviral delivery of three superoxide dismutase genes against hepatic ischemia-reperfusion injury. Human Gene Therapy. 12: 2167-77. PMID 11779401 DOI: 10.1089/10430340152710513  1
2001 Wheeler MD, Kono H, Yin M, Nakagami M, Uesugi T, Arteel GE, Gäbele E, Rusyn I, Yamashina S, Froh M, Adachi Y, Iimuro Y, Bradford BU, Smutney OM, Connor HD, ... ... Samulski RJ, et al. The role of Kupffer cell oxidant production in early ethanol-induced liver disease. Free Radical Biology & Medicine. 31: 1544-9. PMID 11744328 DOI: 10.1016/S0891-5849(01)00748-1  1
2001 Young SM, Samulski RJ. Adeno-associated virus (AAV) site-specific recombination does not require a Rep-dependent origin of replication within the AAV terminal repeat. Proceedings of the National Academy of Sciences of the United States of America. 98: 13525-30. PMID 11707592 DOI: 10.1073/Pnas.241508998  1
2001 Chao H, Monahan PE, Liu Y, Samulski RJ, Walsh CE. Sustained and complete phenotype correction of hemophilia B mice following intramuscular injection of AAV1 serotype vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 4: 217-22. PMID 11545612 DOI: 10.1006/mthe.2001.0449  1
2001 McCarty DM, Monahan PE, Samulski RJ. Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis. Gene Therapy. 8: 1248-54. PMID 11509958 DOI: 10.1038/Sj.Gt.3301514  1
2001 Amiss TJ, Samulski RJ. Methods for adeno-associated virus-mediated gene transfer into muscle. Methods in Molecular Biology (Clifton, N.J.). 175: 455-69. PMID 11462851 DOI: 10.1385/1-59259-235-X:455  1
2001 Wheeler MD, Kono H, Yin M, Rusyn I, Froh M, Connor HD, Mason RP, Samulski RJ, Thurman RG. Delivery of the Cu/Zn-superoxide dismutase gene with adenovirus reduces early alcohol-induced liver injury in rats. Gastroenterology. 120: 1241-50. PMID 11266387 DOI: 10.1053/Gast.2001.23253  1
2000 Chao H, Liu Y, Rabinowitz J, Li C, Samulski RJ, Walsh CE. Several log increase in therapeutic transgene delivery by distinct adeno-associated viral serotype vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 2: 619-23. PMID 11124063 DOI: 10.1006/Mthe.2000.0219  1
2000 Rabinowitz JE, Samulski RJ. Building a better vector: The manipulation of AAV virions Virology. 278: 301-308. PMID 11118354 DOI: 10.1006/Viro.2000.0707  1
2000 Monahan PE, Samulski RJ. Adeno-associated virus vectors for gene therapy: more pros than cons? Molecular Medicine Today. 6: 433-40. PMID 11074369 DOI: 10.1016/S1357-4310(00)01810-4  1
2000 Haberman RP, McCown TJ, Samulski RJ. Novel transcriptional regulatory signals in the adeno-associated virus terminal repeat A/D junction element. Journal of Virology. 74: 8732-9. PMID 10954575 DOI: 10.1128/Jvi.74.18.8732-8739.2000  1
2000 Carter PJ, Samulski RJ. Adeno-associated viral vectors as gene delivery vehicles. International Journal of Molecular Medicine. 6: 17-27. PMID 10851261 DOI: 10.3892/ijmm.6.1.17  1
2000 Samulski RJ. Expanding the AAV package Nature Biotechnology. 18: 497-498. PMID 10802614 DOI: 10.1038/75352  1
2000 Lehmann TG, Wheeler MD, Schoonhoven R, Bunzendahl H, Samulski RJ, Thurman RG. Delivery of Cu/Zn-superoxide dismutase genes with a viral vector minimizes liver injury and improves survival after liver transplantation in the rat Transplantation. 69: 1051-1057. PMID 10762207 DOI: 10.1097/00007890-200003270-00007  1
2000 Young SM, McCarty DM, Degtyareva N, Samulski RJ. Roles of adeno-associated virus Rep protein and human chromosome 19 in site-specific recombination. Journal of Virology. 74: 3953-66. PMID 10756007 DOI: 10.1128/Jvi.74.9.3953-3966.2000  1
2000 Malik AK, Monahan PE, Allen DL, Chen BG, Samulski RJ, Kurachi K. Kinetics of recombinant adeno-associated virus-mediated gene transfer. Journal of Virology. 74: 3555-65. PMID 10729130 DOI: 10.1128/JVI.74.8.3555-3565.2000  1
2000 Pruchnic R, Cao B, Peterson ZQ, Xiao X, Li J, Samulski RJ, Epperly M, Huard J. The use of adeno-associated virus to circumvent the maturation-dependent viral transduction of muscle fibers Human Gene Therapy. 11: 521-536. PMID 10724031 DOI: 10.1089/10430340050015716  1
2000 Bartlett JS, Wilcher R, Samulski RJ. Infectious entry pathway of adeno-associated virus and adeno-associated virus vectors Journal of Virology. 74: 2777-2785. PMID 10684294 DOI: 10.1128/JVI.74.6.2777-2785.2000  1
2000 Monahan PE, Samulski RJ. AAV vectors: is clinical success on the horizon? Gene Therapy. 7: 24-30. PMID 10680012 DOI: 10.1038/Sj.Gt.3301109  1
2000 Young SM, Xiao W, Samulski RJ. Site-specific targeting of DNA plasmids to chromosome 19 using AAV cis and trans sequences. Methods in Molecular Biology (Clifton, N.J.). 133: 111-26. PMID 10561835 DOI: 10.1385/1-59259-215-5:111  1
1999 Rabinowitz JE, Xiao W, Samulski RJ. Insertional mutagenesis of AAV2 capsid and the production of recombinant virus Virology. 265: 274-285. PMID 10600599 DOI: 10.1006/Viro.1999.0045  1
1999 Chao H, Samulski R, Bellinger D, Monahan P, Nichols T, Walsh C. Persistent expression of canine factor IX in hemophilia B canines. Gene Therapy. 6: 1695-704. PMID 10516718 DOI: 10.1038/Sj.Gt.3301024  1
1999 Gavin DK, Young SM, Xiao W, Temple B, Abernathy CR, Pereira DJ, Muzyczka N, Samulski RJ. Charge-to-alanine mutagenesis of the adeno-associated virus type 2 Rep78/68 proteins yields temperature-sensitive and magnesium-dependent variants. Journal of Virology. 73: 9433-45. PMID 10516052  1
1999 Grimm D, Kern A, Pawlita M, Ferrari F, Samulski R, Kleinschmidt J. Titration of AAV-2 particles via a novel capsid ELISA: packaging of genomes can limit production of recombinant AAV-2. Gene Therapy. 6: 1322-30. PMID 10455443 DOI: 10.1038/Sj.Gt.3300946  1
1999 Zolotukhin S, Byrne BJ, Mason E, Zolotukhin I, Potter M, Chesnut K, Summerford C, Samulski RJ, Muzyczka N. Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield. Gene Therapy. 6: 973-85. PMID 10455399 DOI: 10.1038/Sj.Gt.3300938  1
1999 Summerford C, Samulski RJ. Viral receptors and vector purification: New approaches for generating clinical-grade reagents Nature Medicine. 5: 587-558. PMID 10229239 DOI: 10.1038/8470  1
1999 Qiu J, Mizukami H, Brown KE, Qing K, Hansen J, Srivastava A, Samulski RJ, Bartlett JS, Summerford C. Adeno-associated virus 2 co-receptors? [2] (multiple letters) Nature Medicine. 5: 467-468. PMID 10229209 DOI: 10.1038/8328  1
1999 Bartlett JS, Kleinschmidt J, Boucher RC, Samulski RJ. Targeted adeno-associated virus vector transduction of nonpermissive cells mediated by a bispecific F(ab'gamma)2 antibody. Nature Biotechnology. 17: 181-6. PMID 10052356 DOI: 10.1038/6185  1
1999 Summerford C, Bartlett JS, Samulski RJ. αVβ5 integrin: A co-receptor for adeno-associated virus type 2 infection Nature Medicine. 5: 78-82. PMID 9883843 DOI: 10.1038/4768  1
1999 Samulski RJ, Sally M, Muzyczka N. 7 Adeno-associated Viral Vectors Cold Spring Harbor Monograph Archive. 36: 131-172. DOI: 10.1101/087969528.36.131  1
1998 Haberman RP, McCown TJ, Samulski RJ. Inducible long-term gene expression in brain with adeno-associated virus gene transfer. Gene Therapy. 5: 1604-11. PMID 10023439 DOI: 10.1038/Sj.Gt.3300782  1
1998 Teramoto S, Bartlett JS, Mccarty D, Xiao X, Samulski RJ, Boucher RC. Factors influencing adeno-associated virus-mediated gene transfer to human cystic fibrosis airway epithelial cells: Comparison with adenovirus vectors Journal of Virology. 72: 8904-8912. PMID 9765435 DOI: 10.1128/Jvi.72.11.8904-8912.1998  1
1998 During MJ, Samulski RJ, Elsworth JD, Kaplitt MG, Leone P, Xiao X, Li J, Freese A, Taylor JR, Roth RH, Sladek JR, O'Malley KL, Redmond DE. In vivo expression of therapeutic human genes for dopamine production in the caudates of MPTP-treated monkeys using an AAV vector. Gene Therapy. 5: 820-7. PMID 9747462 DOI: 10.1038/Sj.Gt.3300650  1
1998 Bartlett JS, Samulski RJ, McCown TJ. Selective and rapid uptake of adeno-associated virus type 2 in brain. Human Gene Therapy. 9: 1181-6. PMID 9625257 DOI: 10.1089/hum.1998.9.8-1181  1
1998 Bartlett JS, Samulski RJ. Fluorescent viral vectors: A new technique for the pharmacological analysis of gene therapy Nature Medicine. 4: 635-637. PMID 9585242 DOI: 10.1038/Nm0598-635  1
1998 Monahan PE, Samulski RJ, Tazelaar J, Xiao X, Nichols TC, Bellinger DA, Read MS, Walsh CE. Direct intramuscular injection with recombinant AAV vectors results in sustained expression in a dog model of hemophilia. Gene Therapy. 5: 40-9. PMID 9536263 DOI: 10.1038/Sj.Gt.3300548  1
1998 Xiao X, Juan LI, Samulski RJ. Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus Journal of Virology. 72: 2224-2232. PMID 9499080 DOI: 10.1128/Jvi.72.3.2224-2232.1998  1
1998 Summerford C, Samulski RJ. Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions Journal of Virology. 72: 1438-1445. PMID 9445046 DOI: 10.1128/Jvi.72.2.1438-1445.1998  1
1998 Summerford C, Samulski RJ. Adeno-associated viral vectors for gene therapy Biogenic Amines. 14: 451-475.  1
1997 Keir SD, Miller J, Yu G, Hamilton R, Samulski RJ, Xiao X, Tornatore C. Efficient gene transfer into primary and immortalized human fetal glial cells using adeno-associated virus vectors: Establishment of a glial cell line with a functional CD4 receptor Journal of Neurovirology. 3: 322-330. PMID 9372453 DOI: 10.3109/13550289709030746  1
1997 Ferrari FK, Xiao X, McCarty D, Samulski RJ. New developments in the generation of Ad-free, high-titer rAAV gene therapy vectors Nature Medicine. 3: 1295-1297. PMID 9359708 DOI: 10.1038/Nm1197-1295  1
1997 Li J, Samulski RJ, Xiao X. Role for highly regulated rep gene expression in adeno-associated virus vector production Journal of Virology. 71: 5236-5243. PMID 9188591 DOI: 10.1128/Jvi.71.7.5236-5243.1997  1
1997 Xiao X, McCown TJ, Li J, Breese GR, Morrow AL, Samulski RJ. Adeno-associated virus (AAV) vector antisense gene transfer in vivo decreases GABA(A) alpha1 containing receptors and increases inferior collicular seizure sensitivity. Brain Research. 756: 76-83. PMID 9187316 DOI: 10.1016/S0006-8993(97)00120-0  1
1997 Xiao X, Li J, McCown TJ, Samulski RJ. Gene transfer by adeno-associated virus vectors into the central nervous system. Experimental Neurology. 144: 113-24. PMID 9126160 DOI: 10.1006/Exnr.1996.6396  1
1997 Xiao X, Xiao W, Li J, Samulski RJ. A novel 165-base-pair terminal repeat sequence is the sole cis requirement for the adeno-associated virus life cycle Journal of Virology. 71: 941-948. PMID 8995611 DOI: 10.1128/Jvi.71.2.941-948.1997  1
1997 Samulski RJ, During MJ, Kaplitt MG, Xiao X, Redman G, McCown T. Adeno-associated virus vectors yield long-term expression and delivery of potentially therapeutic genes into non-dividing neuronal cells Journal of Neurovirology. 3: S72.  1
1996 Kaplitt MG, Xiao X, Samulski RJ, Li J, Ojamaa K, Klein IL, Makimura H, Kaplitt MJ, Strumpf RK, Diethrich EB. Long-term gene transfer in porcine myocardium after coronary infusion of an adeno-associated virus vector. The Annals of Thoracic Surgery. 62: 1669-76. PMID 8957370 DOI: 10.1016/S0003-4975(96)00946-0  1
1996 Xiao X, Li J, Samulski RJ. Efficient long-term gene transfer into muscle tissue of immunocompetent mice by adeno-associated virus vector Journal of Virology. 70: 8098-8108. PMID 8892935 DOI: 10.1128/Jvi.70.11.8098-8108.1996  1
1996 McKeon C, Samulski RJ. NIDDK Workshop on AAV Vectors: Gene transfer into quiescent cells Human Gene Therapy. 7: 1615-1619. PMID 8864762 DOI: 10.1089/Hum.1996.7.13-1615  1
1996 Bartlett JS, Sethna M, Ramamurthy L, Gowen SA, Samulski RJ, Marzluff WF. Efficient expression of protein coding genes from the murine U1 small nuclear RNA promoters. Proceedings of the National Academy of Sciences of the United States of America. 93: 8852-7. PMID 8799116 DOI: 10.1073/pnas.93.17.8852  1
1996 McCarty DM, Samulski RJ. Adeno-associated virus vectors for gene transfer into erythroid cells Current Topics in Microbiology and Immunology. 218: 75-91. PMID 8794247 DOI: 10.1007/978-3-642-80207-2_6  1
1996 McCown TJ, Xiao X, Li J, Breese GR, Samulski RJ. Differential and persistent expression patterns of CNS gene transfer by an adeno-associated virus (AAV) vector. Brain Research. 713: 99-107. PMID 8724980 DOI: 10.1016/0006-8993(95)01488-8  1
1996 Ferrari FK, Samulski T, Shenk T, Samulski RJ. Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors Journal of Virology. 70: 3227-3234. PMID 8627803 DOI: 10.1128/Jvi.70.5.3227-3234.1996  1
1995 Rolling F, Samulski RJ. AAV as a viral vector for human gene therapy - Generation of recombinant virus Molecular Biotechnology. 3: 9-15. PMID 7606507 DOI: 10.1007/Bf02821330  1
1995 Skulimowski AW, Samulski RJ. [1] Adeno-associated virus: Integrating vectors for human gene therapy Methods in Molecular Genetics. 7: 3-12. DOI: 10.1016/S1067-2389(06)80033-6  1
1994 Goodman S, Xiao X, Donahue RE, Moulton A, Miller J, Walsh C, Young NS, Samulski RJ, Nienhuis AW. Recombinant adeno-associated virus-mediated gene transfer into hematopoietic progenitor cells. Blood. 84: 1492-500. PMID 8068942  1
1994 Walsh CE, Nienhuis AW, Samulski RJ, Brown MG, Miller JL, Young NS, Liu JM. Phenotypic correction of Fanconi anemia in human hematopoietic cells with a recombinant adeno-associated virus vector. The Journal of Clinical Investigation. 94: 1440-8. PMID 7929819 DOI: 10.1172/Jci117481  1
1994 Kaplitt MG, Leone P, Samulski RJ, Xiao X, Pfaff DW, O'Malley KL, During MJ. Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain. Nature Genetics. 8: 148-54. PMID 7842013 DOI: 10.1038/Ng1094-148  1
1994 Miller JL, Donahue RE, Sellers SE, Samulski RJ, Young NS, Nienhuis AW. Recombinant adeno-associated virus (rAAV)-mediated expression of a human gamma-globin gene in human progenitor-derived erythroid cells. Proceedings of the National Academy of Sciences of the United States of America. 91: 10183-7. PMID 7524085 DOI: 10.1073/Pnas.91.21.10183  1
1993 Miller JL, Walsh CE, Ney PA, Samulski RJ, Nienhuis AW. Single-copy transduction and expression of human gamma-globin in K562 erythroleukemia cells using recombinant adeno-associated virus vectors: the effect of mutations in NF-E2 and GATA-1 binding motifs within the hypersensitivity site 2 enhancer. Blood. 82: 1900-6. PMID 8400240  1
1993 Snyder RO, Im DS, Ni T, Xiao X, Samulski RJ, Muzyczka N. Features of the adeno-associated virus origin involved in substrate recognition by the viral rep protein Journal of Virology. 67: 6096-6104. PMID 8396670 DOI: 10.1128/Jvi.67.10.6096-6104.1993  1
1993 Samulski RJ. Adeno-associated virus: integration at a specific chromosomal locus Current Opinion in Genetics and Development. 3: 74-80. PMID 8384035 DOI: 10.1016/S0959-437X(05)80344-2  1
1993 Walsh CE, Liu JM, Miller JL, Nienhuis AW, Samulski RJ. Gene therapy for human hemoglobinopathies. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 204: 289-300. PMID 8234372 DOI: 10.3181/00379727-204-43665  1
1992 Hunter LA, Samulski RJ. Colocalization of adeno-associated virus rep and capsid proteins in the nuclei of infected cells Journal of Virology. 66: 317-324. PMID 1370086 DOI: 10.1128/Jvi.66.1.317-324.1992  1
1992 Walsh CE, Liu JM, Xiao X, Young NS, Nienhuis AW, Samulski RJ. Regulated high level expression of a human gamma-globin gene introduced into erythroid cells by an adeno-associated virus vector. Proceedings of the National Academy of Sciences of the United States of America. 89: 7257-61. PMID 1323131 DOI: 10.1073/Pnas.89.15.7257  1
1992 Muro-Cacho CA, Samulski RJ, Kaplan D. Gene transfer in human lymphocytes using a vector based on adeno-associated virus Journal of Immunotherapy. 11: 231-237. PMID 1318074 DOI: 10.1097/00002371-199205000-00001  1
1992 Samulski RJ, Zhu X, Xiao X, Brook JD, Housman DE, Epstein N, Hunter LA. Corrigendum: Targeted integration of adeno-associated virus (AAV) into human chromosome 19 (The EMBO Journal (1991) 10 (3941-3950)) Embo Journal. 11: 1228.  1
1991 Samulski RJ, Zhu X, Xiao X, Brook JD, Housman DE, Epstein N, Hunter LA. Targeted integration of adeno-associated virus (AAV) into human chromosome 19. The Embo Journal. 10: 3941-50. PMID 1657596  1
1990 Snyder RO, Samulski RJ, Muzyczka N. In vitro resolution of covalently joined AAV chromosome ends Cell. 60: 105-113. PMID 2153052 DOI: 10.1016/0092-8674(90)90720-Y  1
1989 Srivastava CH, Samulski RJ, Lu L, Larsen SH, Srivastava A. Construction of a recombinant human parvovirus B19: adeno-associated virus 2 (AAV) DNA inverted terminal repeats are functional in an AAV-B19 hybrid virus. Proceedings of the National Academy of Sciences of the United States of America. 86: 8078-82. PMID 2554300 DOI: 10.1073/Pnas.86.20.8078  1
1989 Samulski RJ, Chang LS, Shenk T. Helper-free stocks of recombinant adeno-associated viruses: Normal integration does not require viral gene expression Journal of Virology. 63: 3822-3828. PMID 2547998 DOI: 10.1128/Jvi.63.9.3822-3828.1989  1
1988 Samulski RJ, Shenk T. Adenovirus E1B 55-M(r) polypeptide facilitates timely cytoplasmic accumulation of adeno-associated virus mRNAs Journal of Virology. 62: 206-210. PMID 2824848 DOI: 10.1128/Jvi.62.1.206-210.1988  1
1987 Hearing P, Samulski RJ, Wishart WL, Shenk T. Identification of a repeated sequence element required for efficient encapsidation of the adenovirus type 5 chromosome Journal of Virology. 61: 2555-2558. PMID 3599182 DOI: 10.1128/Jvi.61.8.2555-2558.1987  1
1987 Samulski RJ, Chang LS, Shenk T. A recombinant plasmid from which an infectious adeno-associated virus genome can be excised in vitro and its use to study viral replication Journal of Virology. 61: 3096-3101. PMID 3041032  1
1984 Muzyczka N, Samulski RJ, Hermonat P, Srivastava A, Berns KI. The genetics of adeno-associated virus. Advances in Experimental Medicine and Biology. 179: 151-61. PMID 6098150 DOI: 10.1007/978-1-4684-8730-5_15  1
1983 Samulski RJ, Srivastava A, Berns KI, Muzyczka N. Rescue of adeno-associated virus from recombinant plasmids: gene correction within the terminal repeats of AAV. Cell. 33: 135-43. PMID 6088052 DOI: 10.1016/0092-8674(83)90342-2  1
1982 Samulski RJ, Berns KI, Tan M, Muzyczka N. Cloning of adeno-associated virus into pBR322: rescue of intact virus from the recombinant plasmid in human cells. Proceedings of the National Academy of Sciences of the United States of America. 79: 2077-81. PMID 6281795 DOI: 10.1073/Pnas.79.6.2077  1
1980 McMaster GK, Samulski RJ, Stein JL, Stein GS. Rapid purification of covalently closed circular DNAs of bacterial plasmids and animal tumor viruses Analytical Biochemistry. 109: 47-54. PMID 6258457 DOI: 10.1016/0003-2697(80)90008-1  1
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