Erik Falck-Pedersen - Publications

Affiliations: 
Weill Cornell Medical College, New York, NY, United States 
Area:
Immunology, Microbiology Biology

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Weskamp G, Tüshaus J, Li D, Feederle R, Maretzky T, Swendeman S, Falck-Pedersen E, McIlwain DR, Mak TW, Salmon JE, Lichtenthaler SF, Blobel CP. ADAM17 stabilizes its interacting partner inactive Rhomboid 2 (iRhom2) but not inactive Rhomboid 1 (iRhom1). The Journal of Biological Chemistry. PMID 32060096 DOI: 10.1074/Jbc.Ra119.011136  0.324
2017 Janovitz T, Wong S, Young NS, Oliveira T, Falck-Pedersen E. Parvovirus B19 integration into human CD36+ erythroid progenitor cells. Virology. 511: 40-48. PMID 28806616 DOI: 10.1016/J.Virol.2017.08.011  0.375
2017 Huffman JB, Daniel GR, Falck-Pedersen E, Huet A, Smith GA, Conway JF, Homa FL. The C-terminus of the herpes simplex virus pUL25 protein is required for release of viral genomes from capsids bound to nuclear pores. Journal of Virology. PMID 28490590 DOI: 10.1128/Jvi.00641-17  0.366
2016 Anghelina D, Lam E, Falck-Pedersen E. Diminished antiviral innate response to Adenovirus vectors in cGAS/STING deficient mice minimally impacts adaptive immunity. Journal of Virology. PMID 27076643 DOI: 10.1128/Jvi.00500-16  0.476
2014 Lam E, Falck-Pedersen E. Unabated adenovirus replication following activation of the cGAS/STING-dependent antiviral response in human cells. Journal of Virology. 88: 14426-39. PMID 25297994 DOI: 10.1128/Jvi.02608-14  0.484
2014 Janovitz T, Sadelain M, Falck-Pedersen E. Adeno-associated virus type 2 preferentially integrates single genome copies with defined breakpoints. Virology Journal. 11: 15. PMID 24468291 DOI: 10.1186/1743-422X-11-15  0.3
2014 Janovitz T, Oliveira T, Sadelain M, Falck-Pedersen E. Highly divergent integration profile of adeno-associated virus serotype 5 revealed by high-throughput sequencing. Journal of Virology. 88: 2481-8. PMID 24335317 DOI: 10.1128/Jvi.03419-13  0.354
2014 Lam E, Stein S, Falck-Pedersen E. Adenovirus detection by the cGAS/STING/TBK1 DNA sensing cascade. Journal of Virology. 88: 974-81. PMID 24198409 DOI: 10.1128/Jvi.02702-13  0.374
2013 Janovitz T, Klein IA, Oliveira T, Mukherjee P, Nussenzweig MC, Sadelain M, Falck-Pedersen E. High-throughput sequencing reveals principles of adeno-associated virus serotype 2 integration. Journal of Virology. 87: 8559-68. PMID 23720718 DOI: 10.1128/Jvi.01135-13  0.356
2012 Stein SC, Lam E, Falck-Pedersen E. Cell-specific regulation of nucleic acid sensor cascades: a controlling interest in the antiviral response. Journal of Virology. 86: 13303-12. PMID 23015711 DOI: 10.1128/Jvi.02296-12  0.371
2012 Stein SC, Falck-Pedersen E. Sensing adenovirus infection: activation of interferon regulatory factor 3 in RAW 264.7 cells. Journal of Virology. 86: 4527-37. PMID 22345436 DOI: 10.1128/Jvi.07071-11  0.423
2009 Schoggins JW, Falck-Pedersen E. Serotype 5 Adenovirus fiber (F7F41S) chimeric vectors incur packaging deficiencies when targeting peptides are inserted into Ad41 short fiber. Virology. 395: 10-20. PMID 19782383 DOI: 10.1016/J.Virol.2009.08.041  0.663
2009 Diaz F, Gravotta D, Deora A, Schreiner R, Schoggins J, Falck-Pedersen E, Rodriguez-Boulan E. Clathrin adaptor AP1B controls adenovirus infectivity of epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 11143-8. PMID 19549835 DOI: 10.1073/Pnas.0811227106  0.618
2009 Nociari M, Ocheretina O, Murphy M, Falck-Pedersen E. Adenovirus induction of IRF3 occurs through a binary trigger targeting Jun N-terminal kinase and TBK1 kinase cascades and type I interferon autocrine signaling. Journal of Virology. 83: 4081-91. PMID 19211767 DOI: 10.1128/Jvi.02591-08  0.35
2007 Gall J, Schoggins J, Falck-Pedersen E. Adenovirus capsid chimeras: fiber terminal exon insertions/gene replacements in the major late transcription unit. Methods in Molecular Medicine. 130: 107-23. PMID 17401167 DOI: 10.1385/1-59745-166-5:107  0.666
2007 Murphy M, Gomos-Klein J, Stankic M, Falck-Pedersen E. Adeno-associated virus type 2 p5 promoter: a rep-regulated DNA switch element functioning in transcription, replication, and site-specific integration. Journal of Virology. 81: 3721-30. PMID 17267512 DOI: 10.1128/Jvi.02693-06  0.348
2007 Nociari M, Ocheretina O, Schoggins JW, Falck-Pedersen E. Sensing infection by adenovirus: Toll-like receptor-independent viral DNA recognition signals activation of the interferon regulatory factor 3 master regulator. Journal of Virology. 81: 4145-57. PMID 17251283 DOI: 10.1128/Jvi.02685-06  0.658
2006 Schoggins JW, Falck-Pedersen E. Fiber and penton base capsid modifications yield diminished adenovirus type 5 transduction and proinflammatory gene expression with retention of antigen-specific humoral immunity. Journal of Virology. 80: 10634-44. PMID 16943295 DOI: 10.1128/Jvi.01359-06  0.692
2005 Schoggins JW, Nociari M, Philpott N, Falck-Pedersen E. Influence of fiber detargeting on adenovirus-mediated innate and adaptive immune activation. Journal of Virology. 79: 11627-37. PMID 16140740 DOI: 10.1128/Jvi.79.18.11627-11637.2005  0.702
2004 Hamilton H, Gomos J, Berns KI, Falck-Pedersen E. Adeno-associated virus site-specific integration and AAVS1 disruption. Journal of Virology. 78: 7874-82. PMID 15254160 DOI: 10.1128/Jvi.78.15.7874-7882.2004  0.394
2004 Philpott NJ, Nociari M, Elkon KB, Falck-Pedersen E. Adenovirus-induced maturation of dendritic cells through a PI3 kinase-mediated TNF-alpha induction pathway. Proceedings of the National Academy of Sciences of the United States of America. 101: 6200-5. PMID 15071185 DOI: 10.1073/Pnas.0308368101  0.455
2004 Philpott NJ, Gomos J, Falck-Pedersen E. Transgene expression after rep-mediated site-specific integration into chromosome 19. Human Gene Therapy. 15: 47-61. PMID 14965377 DOI: 10.1089/10430340460732454  0.38
2003 Schoggins JW, Gall JG, Falck-Pedersen E. Subgroup B and F fiber chimeras eliminate normal adenovirus type 5 vector transduction in vitro and in vivo. Journal of Virology. 77: 1039-48. PMID 12502819 DOI: 10.1128/Jvi.77.2.1039-1048.2003  0.651
2002 Hu X, Herrero C, Li WP, Antoniv TT, Falck-Pedersen E, Koch AE, Woods JM, Haines GK, Ivashkiv LB. Sensitization of IFN-gamma Jak-STAT signaling during macrophage activation. Nature Immunology. 3: 859-66. PMID 12172544 DOI: 10.1038/Ni828  0.303
2002 Philpott NJ, Giraud-Wali C, Dupuis C, Gomos J, Hamilton H, Berns KI, Falck-Pedersen E. Efficient integration of recombinant adeno-associated virus DNA vectors requires a p5-rep sequence in cis. Journal of Virology. 76: 5411-21. PMID 11991970 DOI: 10.1128/Jvi.76.11.5411-5421.2002  0.442
2001 Trevejo JM, Marino MW, Philpott N, Josien R, Richards EC, Elkon KB, Falck-Pedersen E. TNF-alpha -dependent maturation of local dendritic cells is critical for activating the adaptive immune response to virus infection. Proceedings of the National Academy of Sciences of the United States of America. 98: 12162-7. PMID 11593031 DOI: 10.1073/Pnas.211423598  0.718
2001 Peng Y, Falck-Pedersen E, Elkon KB. Variation in adenovirus transgene expression between BALB/c and C57BL/6 mice is associated with differences in interleukin-12 and gamma interferon production and NK cell activation Journal of Virology. 75: 4540-4550. PMID 11312324 DOI: 10.1128/Jvi.75.10.4540-4550.2001  0.417
2000 Peng Y, Falck-Pedersen E, Elkon KB. Soluble CD8 attenuates cytotoxic T cell responses against replication- defective adenovirus affording transprotection of transgenes in vivo Journal of Immunology. 165: 1470-1478. PMID 10903752 DOI: 10.4049/Jimmunol.165.3.1470  0.325
2000 Nicolás AL, Munz PL, Falck-Pedersen E, Young CS. Creation and repair of specific DNA double-strand breaks in vivo following infection with adenovirus vectors expressing Saccharomyces cerevisiae HO endonuclease. Virology. 266: 211-24. PMID 10612676 DOI: 10.1006/Viro.1999.0062  0.352
1999 Miyazawa N, Leopold PL, Hackett NR, Ferris B, Worgall S, Falck-Pedersen E, Crystal RG. Fiber swap between adenovirus subgroups B and C alters intracellular trafficking of adenovirus gene transfer vectors. Journal of Virology. 73: 6056-65. PMID 10364358 DOI: 10.1128/Jvi.73.7.6056-6065.1999  0.43
1999 Peng Y, Trevejo J, Zhou J, Marino MW, Crystal RG, Falck-Pedersen E, Elkon KB. Inhibition of tumor necrosis factor alpha by an adenovirus-encoded soluble fusion protein extends transgene expression in the liver and lung Journal of Virology. 73: 5098-5109. PMID 10233973 DOI: 10.1128/Jvi.73.6.5098-5109.1999  0.72
1999 Kaner RJ, Worgall S, Leopold PL, Stolze E, Milano E, Hidaka C, Ramalingam R, Hackett NR, Singh R, Bergelson J, Finberg R, Falck-Pedersen E, Crystal RG. Modification of the genetic program of human alveolar macrophages by adenovirus vectors in vitro is feasible but inefficient, limited in part by the low level of expression of the coxsackie/adenovirus receptor. American Journal of Respiratory Cell and Molecular Biology. 20: 361-70. PMID 10030833 DOI: 10.1165/Ajrcmb.20.3.3398  0.464
1998 Gall JG, Crystal RG, Falck-Pedersen E. Construction and characterization of hexon-chimeric adenoviruses: specification of adenovirus serotype. Journal of Virology. 72: 10260-4. PMID 9811772 DOI: 10.1128/Jvi.72.12.10260-10264.1998  0.437
1997 Abrahamsen K, Kong HL, Mastrangeli A, Brough D, Lizonova A, Crystal RG, Falck-Pedersen E. Construction of an adenovirus type 7a E1A- vector Journal of Virology. 71: 8946-8951. PMID 9343264 DOI: 10.1128/Jvi.71.11.8946-8951.1997  0.44
1997 Elkon KB, Liu CC, Gall JG, Trevejo J, Marino MW, Abrahamsen KA, Song X, Zhou JL, Old LJ, Crystal RG, Falck-Pedersen E. Tumor necrosis factor alpha plays a central role in immune-mediated clearance of adenoviral vectors. Proceedings of the National Academy of Sciences of the United States of America. 94: 9814-9. PMID 9275208 DOI: 10.1073/Pnas.94.18.9814  0.729
1997 Prescott JC, Liu L, Falck-Pedersen E. Sequence-mediated regulation of adenovirus gene expression by repression of mRNA accumulation Molecular and Cellular Biology. 17: 2207-2216. PMID 9121471 DOI: 10.1128/Mcb.17.4.2207  0.323
1997 Mack CA, Song WR, Carpenter H, Wickham TJ, Kovesdi I, Harvey BG, Magovern CJ, Isom OW, Rosengart T, Falck-Pedersen E, Hackett NR, Crystal RG, Mastrangeli A. Circumvention of anti-adenovirus neutralizing immunity by administration of an adenoviral vector of an alternate serotype Human Gene Therapy. 8: 99-109. PMID 8989999 DOI: 10.1089/Hum.1997.8.1-99  0.325
1997 Worgall S, Wolff G, Falck-Pedersen E, Crystal RG. Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration. Human Gene Therapy. 8: 37-44. PMID 8989993 DOI: 10.1089/Hum.1997.8.1-37  0.431
1996 Yoon SO, Lois C, Alvirez M, Alvarez-Buylla A, Falck-Pedersen E, Chao MV. Adenovirus-mediated gene delivery into neuronal precursors of the adult mouse brain. Proceedings of the National Academy of Sciences of the United States of America. 93: 11974-9. PMID 8876247 DOI: 10.1073/Pnas.93.21.11974  0.335
1996 Kass-Eisler A, Leinwand L, Gall J, Bloom B, Falck-Pedersen E. Circumventing the immune response to adenovirus-mediated gene therapy Gene Therapy. 3: 154-162. PMID 8867863  0.325
1996 Mastrangeli A, Harvey BG, Yao J, Wolff G, Kovesdi I, Crystal RG, Falck-Pedersen E. "Sero-switch" adenovirus-mediated in vivo gene transfer: Circumvention of anti-Adenovirus humoral immune defenses against repeat adenovirus vector administration by changing the adenovirus serotype Human Gene Therapy. 7: 79-87. PMID 8825871 DOI: 10.1089/Hum.1996.7.1-79  0.432
1996 Gall J, Kass-Eisler A, Leinwand L, Falck-Pedersen E. Adenovirus type 5 and 7 capsid chimera: Fiber replacement alters receptor tropism without affecting primary immune neutralization epitopes Journal of Virology. 70: 2116-2123. PMID 8642632 DOI: 10.1128/Jvi.70.4.2116-2123.1996  0.484
1996 Yeaman C, Heinflink M, Falck-Pedersen E, Rodriguez-Boulan E, Gershengorn MC. Polarity of TRH receptors in transfected MDCK cells is independent of endocytosis signals and G protein coupling. The American Journal of Physiology. 270: C753-62. PMID 8638654 DOI: 10.1152/Ajpcell.1996.270.3.C753  0.309
1993 Kass-Eisler A, Falck-Pedersen E, Alvira M, Rivera J, Buttrick PM, Wittenberg BA, Cipriani L, Leinwand LA. Quantitative determination of adenovirus-mediated gene delivery to rat cardiac myocytes in vitro and in vivo Proceedings of the National Academy of Sciences of the United States of America. 90: 11498-11502. PMID 8265580 DOI: 10.1073/Pnas.90.24.11498  0.396
1993 Edwalds-Gilbert G, Prescott J, Falck-Pedersen E. 3' RNA processing efficiency plays a primary role in generating termination-competent RNA polymerase II elongation complexes Molecular and Cellular Biology. 13: 3472-3480. PMID 7684499 DOI: 10.1128/Mcb.13.6.3472  0.31
1991 DeZazzo JD, Falck-Pedersen E, Imperiale MJ. Sequences Regulating Temporal Poly(A) Site Switching in the Adenovirus Major Late Transcription Unit Molecular and Cellular Biology. 11: 5977-5984. PMID 1944273 DOI: 10.1128/Mcb.11.12.5977  0.314
1989 Falck-Pedersen E, Logan J. Regulation of poly(A) site selection in adenovirus. Journal of Virology. 63: 532-541. PMID 2562992 DOI: 10.1128/Jvi.63.2.532-541.1989  0.307
1985 Falck-Pedersen E, Logan J, Shenk T, Darnell JE. Transcription termination within the E1A gene of adenovirus induced by insertion of the mouse beta-major globin terminator element. Cell. 40: 897-905. PMID 2580640 DOI: 10.1016/0092-8674(85)90349-6  0.348
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